Biotechnology Worldwide

There are several countries that are making special efforts to both develop and capitalise on Biotechnology. Chief amongst them is America, though cutting edge work is also going on in the UK, Ireland, Germany, Korea, Singapore, China and Japan.

• America is the world leader in biotechnology, it has 1,379 biotechnology companies and employs 174,000 people. It spends £9 billion on research into biotechnology. • The European market for goods and services dependent on biotechnology is currently estimated at £30 billion and is forecast to exceed £100 billion by the year 2005 • The UK leads Europe in biotechnology and employs 19,000 people • The UK has 300 dedicated biotechnology companies and a further 250-300 involved in broader bioscience related activities • The industrial sectors which stand to benefit from biotechnology are pharmaceutical, agriculture, food and drink, chemicals and environmental technologies • Germany is the second strongest country in Europe, with 332 companies but fewer products in development than the UK.

UK

The UK biotechnology industry is regarded as second only to the huge effort taking place in the States. UK biotechnology companies generate over a billion pounds in revenue; half of this is pumped back into research and development. The industry has particular strengths, for example:

• Britain was a key player in the world wide project of sequencing the 30,000 genes of the human genome. The announcement of the first working draft of the human genome marks a significant step forward in our understanding of the way in which we understand and develop treatments for incurable genetic conditions. The human genome project has not only enabled the identification of the vital role that genes play in human disease and illness, but to accelerate these discoveries • 75% of the biotechnology drugs in late stage clinical trials in Europe are produced by British companies • The UK Government and The Wellcome Trust have invested £1.4 Billion into the science base to ensure biotechnology research is using the latest technology and methods • The UK has been responsible for key breakthroughs in health research, such as monoclonal antibody production and DNA fingerprinting • Biotechnology derived products represent 25% of new treatments in development, most are aimed at diseases where there are no or unsatisfactory treatments available • UK biotechnology companies are continually developing new products, recent developments include the needle free injection, and leukaemia treatment • Diabetes UK announced the launch of a groundbreaking research programme that will take forward a revolutionary procedure developed in Canada by British surgeon James Shapiro. The procedure involves the transplantation of insulin producing islet cells into people with diabetes who are unable to make their own insulin.

The BioIndustry Association, the trade association for innovative enterprises in the UK's bioscience sector, is the authoritative voice of UK biotechnology. A full list of its members is provided below. For contact and details on each member organisation go to the link http://www.bioindustry.org/cgi-bin/member_list.pl?SITE_ID=84

Full List of the UK BioIndustry Association Members

3i plc 4c Consulting Ltd

A F Engineering Abingworth Management Ltd Acambis plc Adprotech Ltd Advanced Centre for Biochemical Engineering Advent Venture Partners Aeres Biomedical Affymetrix UK Ltd AKOS Healthcare Group Ltd Albachem Ltd Alice Ventures Alizyme Therapeutics Ltd Amedis Pharmaceuticals Ltd Amersham Biosciences Amura Ltd Andersen Caledonia Ltd Andrew Sheard Patent Practice Angel Biotechnology Antisoma plc Apax Partners & Co Ventures Ltd Arakis Ltd Ardana BioScience Limited Ark Therapeutics Arnold & Porter Ashurst Morris Crisp Astex Technology Atlas Ventures Australian Trade Commission Avecia LifeScience Molecules Avidex Avlar BioVentures Limited

Babraham Bioscience Technologies Ltd Baker & McKenzie Barlow Lyde & Gilbert BBSRC BCG Europe BDKT The Consortium for Life Science Technologies Bench International BEOCARTA Bevan Ashford BIA Scotland Biggart Baillie BIO BioAnalab Ltd BioBridge Biocatalysts Ltd BioCity Ltd BioCommerce Data Ltd Biocompatibles International plc BioFocus plc BioIndustry Association BioInvent BioMed Research Consulting Ltd BioPharm Services Limited BioScience Managers BioScience York Biostrategy Associates Biotechnology Southwest Ltd Biotica Technology Limited Bird & Bird Bovis Lend Lease Pharmaceutical Bridgehead Technologies Ltd Bristows British Biotech plc Brunswick Bryan Cave BTG Buchanan Communications Business Link for London Business Link Hertfordshire Business Link Surrey Business Therapies

Cambridge Antibody Technology Group plc Cambridge Biomedical Consultants Cambridge Research Biochemicals Ltd Cambridge University Challenge Fund CAMR (Centre for Applied Microbiology & Research) Cancer Research Techology CEL International Ltd CellFactors plc Centre of Excellence in Life Sciences Ltd Cephalon - Europe Chiron Corporation Ltd Chubb Insurance Company of Europe, SA. Clifford Chance CMS Cameron McKenna CNAP Cobra Bio-Manufacturing Controlled Therapeutics Coulter Partners Covance Consulting Services Covington & Burling Crane Process Flow Technology Ltd CRC Phase I/ll Clinical Trials Committee Formulation Unit Critical I Cyclacel Ltd

D Young & Co David Keltie Associates David Solomon DB Technologies De Novo Pharmaceuticals Deloitte & Touche Delta Biotechnology Ltd Denton Wilde Sapte Diagnostic Potentials Ltd Dr Jeff Robinson Dr Naja Joslin Kjeldsen Dr Palie Smart Dr Paul Drayson DSTL Durlacher Ventures Ltd DxS Limited

E-Scape Recruitment Services Ltd East Midlands Development Agency Eastern Region Biotechnology Eden Biopharm Ltd Egon Zehnder International Elkington and Fife Envirolink Northwest Environmental Industries Commission ERA Consulting (UK) Ltd. Eric Potter Clarkson Ernst & Young Ethicon Ltd Euromedica plc Eversheds Evolution Beeson Gregory Evolution Consultants Ltd Excell Biotech

Financial Dynamics fJ Cleveland Freshfields Bruckhaus Deringer Fulcrum Pharma Developments Ltd

GCI Ltd Gendel Ltd GeneMedix plc Gentronix Ltd Genzyme Pharmaceuticals Ltd Gillies O'Bryan -Tear Grant Thornton GSK

Hale and Dorr Hannah Research Institute Harvey Nash HCC De Facto Group plc Heath Lambert Group Heidrick and Struggles International Herbert Smith Heriot-Watt University Hewitson Becke + Shaw Highland Psychiatric Research Foundation Hilary Newiss Hoodless Brennan & Partners Plc Hunter Fleming Ltd Huntingdon Life Sciences

Iclectus Limited Imperial College Innovations Ltd Inpharmatica Interea International Ltd Intuitive Process Inveresk Research Ltd Invermay Consulting Inverness Medical Ltd Ionix Pharmaceuticals

J. Wynne Williams & Co. J.A. Kemp & Co Jeremy Curnock Cook Johnson & Johnson Development Corp.

Kilburn & Strode Kincannon and Reed Kirkland & Ellis International KLegal Korn/ Ferry International Kryotrans Limited KS Biomedix Holdings Plc

LAB901 Ltd Laxdale Limited LGC Linklaters Lloyds TSB Commercial London School of Hygiene and Tropical Medicine Lonza Biologics plc Lorantis Limited Lovells

Maclay Murray and Spens Malaria Foundation Manches Manchester Innovation Marazzi Romcoli Zotti and Partners Marcus Ridley Associates Marix Drug Development Martineau Johnson Mayer, Brown, Rowe & Maw McDermott Will & Emery McGrigor Donald MDS Pharma Services Medea Consulting Medical Device In Scotland Medical Research Council Technology Mercia Biotech Merlin BioSciences Ltd MerseyBIO Metris Therapeutics Limited Microscience Ltd Mills & Reeve MolecularNature Ltd MPC Executive Search Services Mr James C Taylor MRC Technology (Scotland) MTS Business Communications Murgitroyd & Company Mylnefield Research Services Ltd New Bridge Street Consultants New Business Horizons Ltd

Nomura PLC Noonan/Russo Ltd North West Development Agency - BioNow Northbank Communications NPL Management Limited Nuffield Council of BioEthics

Olswang ONYVAX Ltd Osborne Clarke OSI Pharmaceuticals Oxagen Ltd Oxford BioMedica plc Oxford GlycoSciences Plc Oxford Therapeutics Consulting Ltd Oxxon Pharmaccines Ltd Oxygen Healthcare

PA Consulting Group PanTherix Paradigm Therapeutics Paul Pattinson Penna Consulting plc People in Health Ltd Pharmagene Plc Pharmalicensing Phase Forward Europe Ltd. Physiomics Pinsent Curtis Biddle PIR Group PJ Bio Pleiad Group Limited PPL Therapeutics plc PRI Group PricewaterhouseCoopers Professor Brian J Tighe Profiad Profile Therapeutics ProPharma ProPharma Partners Prophilian Ltd Prospect Management Services Prospero Biotech Ltd Proteom Ltd Proteome Sciences plc Protherics

Q-One Biotech QuA Vodis Ltd Queensland Government Office - Europe Quest Management Quester Capital Management Ltd Quintiles Limited

RBC Consulting Regester Larkin Ltd Renaissance Partners Reneuron Ltd Renovo Ltd Rentschler Biotechnologie GmbH & Co KG Riverside Biosciences Ltd Robin Nott Roche Products Ltd Roslin Institute Rowett Research Services Ltd RSA Search & Selection Russell Reynolds Associates Ruston Poole International plc

Schroder Ventures Life Sciences Advisers (UK) Ltd Science Ventures Ltd Scientific Generics Sciona Ltd Scottish Agricultural College Scottish Colleges Biotechnology Consortium Scottish Crop Research Institute Scottish Enterprise Biotechnology Scottish Health Innovations Serologicals Ltd Serono Pharmaceutical Shire Pharmaceuticals Group plc Simmons & Simmons SJ Berwin Slaughter and May SmartBead Technologies Ltd SNBTS Solutia Pharmaceutical Services Sosei Co. Ltd. SOUTH WEST RDA South Yorkshire Bioscience Enterprise Network (SYBEN) Southampton Institute Southern Bioscience Springman Tipper Campbell Partnership Ltd SR Pharma SRG (Science Recruitment Group) Stedim Stevens Hewlett & Perkins Stratagem Intellectual Property Management Ltd Stringer Saul Suzanne McLean Synaptech Consultants Ltd Synaptica Syngenix Syntil Ltd

Talentmark Targeting Technology Ltd Taylor Vinters Taylor Wessing Tayside Pharmaceuticals Ltd Technical Photo Systems Ltd Technomark Consulting Services Ltd Tepnel Scientific Sevices The Acrobot Company Ltd The Government of Victoria - Australia The Miller Insurance Group The School of Pharmacy, University of London The Wolfson Institute for Biomedical Research TopoTarget UK Ltd Transgenomics Inc Trigen Ltd

UCL Ventures University of Aberdeen University of University of Leicester University of Nottingham University of Southampton University of St Andrews University of Strathclyde University of Sussex

Vaughan, Dr Caroline VeriCore Limited Vernalis Group plc Vertex Pharmaceuticals (Europe) Ltd Viridian EHC Limited

Wates Construction Weil Gotshal & Manges West LB Panmure Ltd Western Arc BioScience Platform Wheb Partnership Willoughby & Partners Withers & Rodgers Wood Mackenzie Ltd Wragge and Co Wright Johnstone & Mackenzie

Xcellsyz Ltd Xenova Group plc XTL Biopharmaceuticals XtruTex Ltd

Yorkshire Forward