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Reforming Eugenics
Working Papers on the Nature of Evidence: How Well Do “Facts” Travel? No. 12/06 Confronting the Stigma of Perfection: Genetic Demography, Diversity and the Quest for a Democratic Eugenics in the Post-war United States Edmund Ramsden © Edmund Ramsden Department of Economic History London School of Economics August 2006 how ‘facts’ “The Nature of Evidence: How Well Do ‘Facts’ Travel?” is funded by The Leverhulme Trust and the E.S.R.C. at the Department of Economic History, London School of Economics. For further details about this project and additional copies of this, and other papers in the series, go to: http://www.lse.ac.uk/collection/economichistory/ Series Editor: Dr. Jon Adams Department of Economic History London School of Economics Houghton Street London WC2A 2AE Email: [email protected] Tel: +44 (0) 20 7955 6727 Fax: +44 (0) 20 7955 7730 Confronting the Stigma of Perfection: Genetic Demography, Diversity and the Quest for a Democratic Eugenics in the Post- war United States1 Edmund Ramsden Abstract Eugenics has played an important role in the relations between social and biological scientists of population through time. Having served as a site for the sharing of data and methods between disciplines in the early twentieth century, scientists and historians have tended to view its legacy in terms of reduction and division - contributing distrust, even antipathy, between communities in the social and the biological sciences. Following the work of Erving Goffman, this paper will explore how eugenics has, as the epitome of “bad” or “abnormal” science, served as a “stigma symbol” in the politics of boundary work. -
Vernon M. Ingram the WILLIAM ALLAN MEMORIAL AWARD Presented at the Annual Meeting of the American Society of Human Genetics Toronto December 1, 1967
Vernon M. Ingram THE WILLIAM ALLAN MEMORIAL AWARD Presented at the annual meeting of the American Society of Human Genetics Toronto December 1, 1967 CITATION The contributions for which we honor Vernon Ingram represent a landmark in the history of molecular biology. Using an ingenious technique, he showed in 1956 that the difference between normal and sickle hemoglobin was caused by a single amino acid substitution. This work, followed by his demonstration of a similar mechanism for hemoglobin C and hemo- globin E, established clearly the nature of mutations in structural proteins and laid the groundwork for our concepts of gene action on the molecular level. 287 288 THE WILLIAM ALLAN MEMORIAL AWARD Vernon Ingram's investigations played a key role in the full integration of human genetics into the mainstream of modern genetic research. For the first time in the history of genetics, a phenomenon of fundamental significance for all forms of life was first demonstrated in man. Human genetics had come of age and became respectable to our more basically inclined colleagues. Vernon Ingram, as a scientist, represents a model for our students. Some investigators are analytical, while others are synthesizers and paint a broad sweep. Some are lone workers, others perform better in a team. Most biologists work in one field-within the framework of Ingram's interests, either as biochemists, as hematologists, as geneticists, or as evolutionists. Vernon Ingram has performed with versatility and distinction in all of these roles. As an analytical chemist, he developed the "fingerprinting" method of peptide separation, which he used to test theories of mutations. -
SOHASKY-DISSERTATION-2017.Pdf (2.074Mb)
DIFFERENTIAL MINDS: MASS INTELLIGENCE TESTING AND RACE SCIENCE IN THE TWENTIETH CENTURY by Kate E. Sohasky A dissertation submitted to the Johns Hopkins University in conformity with the requirements for the degree of Doctor of Philosophy. Baltimore, Maryland May 9, 2017 © Kate E. Sohasky All Rights Reserved ABSTRACT Historians have argued that race science and eugenics retreated following their discrediting in the wake of the Second World War. Yet if race science and eugenics disappeared, how does one explain their sudden and unexpected reemergence in the form of the neohereditarian work of Arthur Jensen, Richard Herrnstein, and Charles Murray? This dissertation argues that race science and eugenics did not retreat following their discrediting. Rather, race science and eugenics adapted to changing political and social climes, at times entering into states of latency, throughout the twentieth century. The transnational history of mass intelligence testing in the twentieth century demonstrates the longevity of race science and eugenics long after their discrediting. Indeed, the tropes of race science and eugenics persist today in the modern I.Q. controversy, as the dissertation shows. By examining the history of mass intelligence testing in multiple nations, this dissertation presents narrative of the continuity of race science and eugenics throughout the twentieth century. Dissertation Committee: Advisors: Angus Burgin and Ronald G. Walters Readers: Louis Galambos, Nathaniel Comfort, and Adam Sheingate Alternates: François Furstenberg -
Sequencing As a Way of Work
Edinburgh Research Explorer A new insight into Sanger’s development of sequencing Citation for published version: Garcia-Sancho, M 2010, 'A new insight into Sanger’s development of sequencing: From proteins to DNA, 1943-77', Journal of the History of Biology, vol. 43, no. 2, pp. 265-323. https://doi.org/10.1007/s10739-009- 9184-1 Digital Object Identifier (DOI): 10.1007/s10739-009-9184-1 Link: Link to publication record in Edinburgh Research Explorer Document Version: Peer reviewed version Published In: Journal of the History of Biology Publisher Rights Statement: © Garcia-Sancho, M. (2010). A new insight into Sanger’s development of sequencing: From proteins to DNA, 1943-77. Journal of the History of Biology, 43(2), 265-323. 10.1007/s10739-009-9184-1 General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights. Take down policy The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer content complies with UK legislation. If you believe that the public display of this file breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. Download date: 28. Sep. 2021 THIS IS AN ADVANCED DRAFT OF A PUBLISHED PAPER. REFERENCES AND QUOTATIONS SHOULD ALWAYS BE MADE TO THE PUBLISHED VERION, WHICH CAN BE FOUND AT: García-Sancho M. -
FA Family News 3/01
FAMILY NEWSLETTER #29 A Semi-annual Newsletter on Fanconi Anemia for Families, Physicians, and Research Scientists Spring 2001 Researchers, treating physicians, and FA parents attended the FA Scientific Symposium in October. HIGHLIGHTS Fanconi Anemia Plan to Attend August Scientific Symposium Family Meeting! Discoveries Reported...................2 One hundred fifty-six researchers, Our 10th annual FA Family Meet- Gene Therapy Trial to Begin.......2 treating physicians, and fifteen FA par- ing is seven months away, but now is ents from fourteen countries met in the time to start planning. This year, Bone Marrow Transplant Conference Planned .................2 Amsterdam for the Twelfth Annual we will offer a limited number of schol- International FA Scientific Sympo- arships to help families defray travel Comparison Between sium, October 26-29, 2000. Coun- and lodging expenses (see article, p. 11). Complementation Group and Mutations, and Clinical tries represented were Tunisia, France, From August 10-14, 2001, FA fam- Outcomes...................................3 England, Canada, Spain, Italy, Ger- ilies, treating physicians, and research- many, Argentina, Israel, Japan, South ers will meet at the picturesque lake- Fludarabine-Based Regimen for Alternate Donor Hemato- Africa, Russia, The Netherlands and front setting of Aurora University’s poietic Cell Transplantation....4 the United States. Fifty-one scientists George Williams Lake Geneva cam- and treating physicians gave formal pus in Williams Bay, Wisconsin. We New Promising Vectors for presentations. Evaluations from atten- will learn from our experts, meet and Gene Therapy ............................4 dees confirmed, once again, that our share experiences with other FA fam- Preimplantation Genetic annual scientific meeting is an out- ilies, and relax. -
International Journal of Pediatrics and Neonatal Health, 2 (1)
Twenty-seven years of controversy: The perils of PGD Item Type Article Authors Cherkassky, Lisa Citation Cherkassky, L. (2018) 'Twenty-seven years of controversy: The perils of PGD', International Journal of Pediatrics and Neonatal Health, 2 (1). Publisher BioCore Journal International Journal of Pediatrics and Neonatal Health Download date 25/09/2021 21:30:55 Link to Item http://hdl.handle.net/10545/622151 Lisa Cherkassky (2017). Twenty-Seven Years of Controversy: The Perils of PGD. Int J Ped & Neo Heal. 1:6, International Journal of Pediatrics and Neonatal Health ISSN 2572-4355 Review Article Open Access Twenty-Seven Years of Controversy: The Perils of PGD Lisa Cherkassky Senior Lecturer in Law, Derby Law School , University of Derby, UK *Corresponding Author: Lisa Cherkassky, Senior Lecturer in Law, Derby Law School , University of Derby, UK, Tel: 01332 591806, E-Mail: [email protected] Citation: Lisa Cherkassky (2017). Twenty-Seven Years of Controversy: The Perils of PGD. Int J Ped & Neo Heal. 1:6, Copyright: © 2017 Lisa Cherkassky. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Received November 28, 2017 ; Accepted December 08, 2017 ; Published XXXX, 2017. Abstract It has been 27 years since the Human Fertilisation and Embryology Act 1990 was passed in the United Kingdom in response to advances in fertility treatment. Preimplantation genetic diagnosis - the screening of embryos for genetic diseases - has led to lengthy ethical de- bates on sex selection, eugenics, disabilities, saviour siblings, surplus embryos and most recently, adult-onset diseases (the BRCA cancer gene). -
Perutz Letters
04_PerutzLet_1950_223-272.qxd:Layout 1 1/12/09 12:26 PM Page 261 Copyright 2009 Cold Spring Harbor Laboratory Press. Not for distribution. Do not copy without written permission from Cold Spring Harbor Laboratory Press. Selected Letters: 1950s 261 To Harold Himsworth, August 24, 1956 I am writing to tell you of exciting developments in the work of our unit. The first news is the discovery by Dr. Vernon Ingram of a definite chemi- cal difference between the globins of sickle cell anaemia and normal haemo- globin. Ingram has devised a new and rapid method of characterising proteins in considerable detail. This consists in first digesting the protein with trypsin and then spreading out the peptides of the digest on a two-dimensional chro- matogram, using electrophoresis in one direction and chromatography in the other. By applying this method to the two haemoglobins Ingram finds that all the 30 odd peptides in the digest are alike except for a single one. This peptide is uncharged in normal haemoglobin and carries a positive charge in haemo- globin S. The size of the peptide is probably of the order of 10 amino-acid residues. Ingram is now going to set about to determine the composition and sequence of the residues in the two peptides. This discovery is particularly interesting, Vernon Ingram in the because the change in structure from normal to early 1950s sickle cell haemoglobin is thought to be due to the action of one single gene, and the action of genes is thought to consist in determining the sequence of residues in a polypeptide chain. -
The Rhesus Factor and Disease Prevention
THE RHESUS FACTOR AND DISEASE PREVENTION The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 3 June 2003 Edited by D T Zallen, D A Christie and E M Tansey Volume 22 2004 ©The Trustee of the Wellcome Trust, London, 2004 First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2004 The Wellcome Trust Centre for the History of Medicine at University College London is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 0 85484 099 1 Histmed logo images courtesy Wellcome Library, London. Design and production: Julie Wood at Shift Key Design 020 7241 3704 All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/ Please cite as : Zallen D T, Christie D A, Tansey E M. (eds) (2004) The Rhesus Factor and Disease Prevention. Wellcome Witnesses to Twentieth Century Medicine, vol. 22. London: Wellcome Trust Centre for the History of Medicine at UCL. CONTENTS Illustrations and credits v Witness Seminars: Meetings and publications;Acknowledgements vii E M Tansey and D A Christie Introduction Doris T Zallen xix Transcript Edited by D T Zallen, D A Christie and E M Tansey 1 References 61 Biographical notes 75 Glossary 85 Index 89 Key to cover photographs ILLUSTRATIONS AND CREDITS Figure 1 John Walker-Smith performs an exchange transfusion on a newborn with haemolytic disease. Photograph provided by Professor John Walker-Smith. Reproduced with permission of Memoir Club. 13 Figure 2 Radiograph taken on day after amniocentesis for bilirubin assessment and followed by contrast (1975). -
Clinical Genetics in Britain: Origins and Development
CLINICAL GENETICS IN BRITAIN: ORIGINS AND DEVELOPMENT The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 23 September 2008 Edited by P S Harper, L A Reynolds and E M Tansey Volume 39 2010 ©The Trustee of the Wellcome Trust, London, 2010 First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2010 The Wellcome Trust Centre for the History of Medicine at UCL is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 085484 127 1 All volumes are freely available online following the links to Publications/Wellcome Witnesses at www.ucl.ac.uk/histmed CONTENTS Illustrations and credits v Abbreviations vii Witness Seminars: Meetings and publications; Acknowledgements E M Tansey and L A Reynolds ix Introduction Sir John Bell xix Transcript Edited by P S Harper, L A Reynolds and E M Tansey 1 Appendix 1 Initiatives supporting clinical genetics, 1983–99 by Professor Rodney Harris 83 Appendix 2 The Association of Genetic Nurses and Counsellors (AGNC) by Professor Heather Skirton 87 References 89 Biographical notes 113 Glossary 133 Index 137 ILLUSTRATIONS AND CREDITS Figure 1 Professor Lionel Penrose, c. 1960. Provided by and reproduced with permission of Professor Shirley Hodgson. 8 Figure 2 Dr Mary Lucas, clinical geneticist at the Galton Laboratory, explains a poster to the University of London’s Chancellor, Princess Anne, October 1981. Provided by and reproduced with permission of Professor Joy Delhanty. 9 Figure 3 (a) The karyotype of a phenotypically normal woman and (b) family pedigree, showing three generations with inherited translocation. -
The Ukrainian Weekly 1991
їкЬей by the Ukrainian National Association Inc., a fraternal non-profit association! rainian WeeklУ Vol. LIX Ш THE UKRAINIAN WEEKLY SUNDAY, APRIL 21,1991 50 cents No. 16 Scientist says Chornobyl Miners, workers protest in Kiev claimed 10,000 lives Republican strike leader is arrested JERSEY CITY, N.J. - Vladimir explosion and that, "Three months ago by Marta Koiomayets arrived from all coal-producing regions Chernousenko, the scientific director in one of the people who participated in Kiev Press Bureau in Ukraine - from Volyn to Luhanske charge of the 20-mile exclusion zone limiting the damage of the accident died — on April 15 and 16 to demand that surrounding the Chornobyl nuclear in Kiev." KIEV - Dmytro Poyizd, the legal their government guarantee them and consultant for the newly formed the citizens of their republic a better power plant, said that the Chornobyl He further stated that "Some of the disaster claimed between 7,000 and Republican Strike Committee, was future — a future that includes free people involved in limiting the damage arrested early in the morning on Thurs dom for Ukraine. 10,000 lives, far more than the Soviet to Chornobyl received (radiation) doses government's official figures, reported day, April 18, just hours after he Angered upon learning the fate of one above the maximum...in fact 145 people organized a miners' and workers' sit-in of their leaders, the miners began the April 14 edition of the British came down with acute radiation newspaper Independent on Sunday. along the Khreshchatyk boulevard, planning anew strategy on Thursday sickness." Other scientists contacted at reported Bohdan Ternopilsky, vice- morning. -
Orme) Wilberforce (Albert) Raymond Blackburn (Alexander Bell
Copyrights sought (Albert) Basil (Orme) Wilberforce (Albert) Raymond Blackburn (Alexander Bell) Filson Young (Alexander) Forbes Hendry (Alexander) Frederick Whyte (Alfred Hubert) Roy Fedden (Alfred) Alistair Cooke (Alfred) Guy Garrod (Alfred) James Hawkey (Archibald) Berkeley Milne (Archibald) David Stirling (Archibald) Havergal Downes-Shaw (Arthur) Berriedale Keith (Arthur) Beverley Baxter (Arthur) Cecil Tyrrell Beck (Arthur) Clive Morrison-Bell (Arthur) Hugh (Elsdale) Molson (Arthur) Mervyn Stockwood (Arthur) Paul Boissier, Harrow Heraldry Committee & Harrow School (Arthur) Trevor Dawson (Arwyn) Lynn Ungoed-Thomas (Basil Arthur) John Peto (Basil) Kingsley Martin (Basil) Kingsley Martin (Basil) Kingsley Martin & New Statesman (Borlasse Elward) Wyndham Childs (Cecil Frederick) Nevil Macready (Cecil George) Graham Hayman (Charles Edward) Howard Vincent (Charles Henry) Collins Baker (Charles) Alexander Harris (Charles) Cyril Clarke (Charles) Edgar Wood (Charles) Edward Troup (Charles) Frederick (Howard) Gough (Charles) Michael Duff (Charles) Philip Fothergill (Charles) Philip Fothergill, Liberal National Organisation, N-E Warwickshire Liberal Association & Rt Hon Charles Albert McCurdy (Charles) Vernon (Oldfield) Bartlett (Charles) Vernon (Oldfield) Bartlett & World Review of Reviews (Claude) Nigel (Byam) Davies (Claude) Nigel (Byam) Davies (Colin) Mark Patrick (Crwfurd) Wilfrid Griffin Eady (Cyril) Berkeley Ormerod (Cyril) Desmond Keeling (Cyril) George Toogood (Cyril) Kenneth Bird (David) Euan Wallace (Davies) Evan Bedford (Denis Duncan) -
Max Perutz (1914–2002)
PERSONAL NEWS NEWS Max Perutz (1914–2002) Max Perutz died on 6 February 2002. He Nobel Prize for Chemistry in 1962 with structure is more relevant now than ever won the Nobel Prize for Chemistry in his colleague and his first student John as we turn attention to the smallest 1962 after determining the molecular Kendrew for their work on the structure building blocks of life to make sense of structure of haemoglobin, the red protein of haemoglobin (Perutz) and myoglobin the human genome and mechanisms of in blood that carries oxygen from the (Kendrew). He was one of the greatest disease.’ lungs to the body tissues. Perutz attemp- ambassadors of science, scientific method Perutz described his work thus: ted to understand the riddle of life in the and philosophy. Apart from being a great ‘Between September 1936 and May 1937 structure of proteins and peptides. He scientist, he was a very kindly and Zwicky took 300 or more photographs in founded one of Britain’s most successful tolerant person who loved young people which he scanned between 5000 and research institutes, the Medical Research and was passionately committed towards 10,000 nebular images for new stars. Council Laboratory of Molecular Bio- societal problems, social justice and This led him to the discovery of one logy (LMB) in Cambridge. intellectual honesty. His passion was to supernova, revealing the final dramatic Max Perutz was born in Vienna in communicate science to the public and moment in the death of a star. Zwicky 1914. He came from a family of textile he continuously lectured to scientists could say, like Ferdinand in The Tempest manufacturers and went to the Theresium both young and old, in schools, colleges, when he had to hew wood: School, named after Empress Maria universities and research institutes.