DOCSLIB.ORG

The Ukrainian Weekly 1991

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
The Ukrainian Weekly 1991 їкЬей by the Ukrainian National Association Inc., a fraternal non-profit association! rainian WeeklУ Vol. LIX Ш THE UKRAINIAN WEEKLY SUNDAY, APRIL 21,1991 50 cents No. 16 Scientist says Chornobyl Miners, workers protest in Kiev claimed 10,000 lives Republican strike leader is arrested JERSEY CITY, N.J. - Vladimir explosion and that, "Three months ago by Marta Koiomayets arrived from all coal-producing regions Chernousenko, the scientific director in one of the people who participated in Kiev Press Bureau in Ukraine - from Volyn to Luhanske charge of the 20-mile exclusion zone limiting the damage of the accident died — on April 15 and 16 to demand that surrounding the Chornobyl nuclear in Kiev." KIEV - Dmytro Poyizd, the legal their government guarantee them and consultant for the newly formed the citizens of their republic a better power plant, said that the Chornobyl He further stated that "Some of the disaster claimed between 7,000 and Republican Strike Committee, was future — a future that includes free­ people involved in limiting the damage arrested early in the morning on Thurs­ dom for Ukraine. 10,000 lives, far more than the Soviet to Chornobyl received (radiation) doses government's official figures, reported day, April 18, just hours after he Angered upon learning the fate of one above the maximum...in fact 145 people organized a miners' and workers' sit-in of their leaders, the miners began the April 14 edition of the British came down with acute radiation newspaper Independent on Sunday. along the Khreshchatyk boulevard, planning anew strategy on Thursday sickness." Other scientists contacted at reported Bohdan Ternopilsky, vice- morning. Wearing their bright orange The Independent quoted Mr. Cher­ the conference were also skeptical of nousenko as saying that the fatalities chairman of the Political Council of hardhats, many of which identify the Mr. Chernousenko's claim of thou­ Rukh. region and mine they work in, the included miners and military men sands of deaths, reported Reuters. exposed to radiation during the clean­ Mr. Poyizd has been instrumental in miners began chanting "Shame to the up and that he had come forward, in (Continued on page 13) organizing the hundreds of miners who (Continued on page 10) part, because he himself was given two to four years to live because of his exposure to radiation. Ukrainian deputies study American democracy On April 16, at an international conference on the lessons of Chornobyl by Chrystyna N. Lapychak held in Paris, Leonid Ilyin, director of the Soviet Institute of Biophysics, WASHINGTON - "The history of refuted Mr. Chernousenko's claim and r your democracy in the United States is stated, "That does not correspond to truly a history. We are only creating our facts," reported Reuters news service. history as a democracy and we would like to make full use of all the best that Mr. Ilyin said that only 28 people was created by different Parliaments in died of high radiation doses or radia­ different countries," declared 01ek- tion burns in the two months after the sander Moroz, leader of the Communist majority in Ukraine's Parliament, last week in Washington. Stepan Khmara Mr. Moroz was one of a delegation of 13 deputies of the Ukrainian SSR Supreme Soviet who participated in an is rearrested unprecedented nine-day "Conference on the American System of Governance in Donetske for Ukrainian Legislators" that brought them to Indiana and Washington, D.C. by Marta Koiomayets on April 4-13. The seminar, as well as Kiev Press Bureau meetings with national, state and local officials was arranged by Indiana KIEV - Outspoken Ukrainian University and NKM Associates of People's Deputy Stepan Khmara was Washington, under the auspices of the rearrested as he arrived in Donetske to United States Information Agency. meet; with striking miners in this south­ "This conference has provided new eastern coal-producing region on Fri­ reasons for us to work more dynami­ day morning, April і 2. He was taken to cally and more rapidly to break Ukraine prison in the city of Sumy, northern out of its isolation and to enhance the Ukraine, and immediately declared a image of our state and of Ukrainians hunger strike on Saturday, April 13. outside its borders," said Ivan Zayets, a It was unclear why Dr. Khmara was deputy from the democratic opposition rearrested just one week after the in the Ukrainian Parliament, during a Supreme Court of the Ukrainian SSR break from one of the many panels. released him on Friday, April 5, until Most of the participating deputies, 12 his court appearance, which had been men and one woman, represented the scheduled for April 29. That date has democratic opposition organized into now been postponed until May 14. the Narodna Rada with 125 members. However, Dr. Khmara's defense Only Mr. Moroz represented the Com­ team, Rukh lawyers Yuny Aivasian and munist majority, known as the "Group Viktor Nikazakov, issued a statement of 239," while Ivan Pliushch, vice- on April 16 which discloses that Dr. chairman of the Supreme Soviet, repre­ Khmara was rearrested based on evi­ sented the "center." Six participants dence provided by Gen. Volodymyr were members of the Ukrainian Parlia­ Nedryhailo from the Ministry of the ment's Presidium, including Messrs. Interior, who chronicled every move Pliushch and Moroz, Pavio Movchan, Natalie Sluzar made by Dr. Khmara from the moment Volodymyr Pylypchuk, Oleksander Ukrainian Parliamentary delegation visits Taras Shevchenko monument in of his release on April 5. Yemets and Dmytro Pavlychko, who Washington during USIA-sponsored conference on the American system of (Continued on page 2) (Continued on page 8) governance. 2 THE UKRAINIAN WEEKLY SUNDAY, APRIL 21, 1991 . No. 16 ment for the fact that he expressed his Stepcm Khmara... opinions. (Continued from page 1) Another question that remains un­ According to the lawyers, Di\ Kh- answered by the Supreme Court is why Newsbriefs from mara and the deputies under whose Dr. Khmara was taken to Sumy instead recognizance he was released guaran­ of being returned to Kiev's Lukianivka Ukraine, USSR teed only that Dr. Khmara would Prison, where he spent his first five appear in court on April 29; thus Dr. months awaiting trial on charges Khmara did not disobey any orders. stemming from a November 7, 1990, scuffle with a plainclothes officer. ^ NEW YORK - Ukrainian State ecological association) and the Kiev City People's Deputy Khmara has been Television and Radio will conduct a Council; Chornobyl hearings, April 22- accused by the Supreme Court, which Demoratic leaders, as well as citizens tele-radio-thon on April 26 called "Bells 25, sponsored by Zelenyi Svit and the issued the warrant for his rearrest, of Ukraine and striking miners who of Chornobyl" to commemorate the Chornobyl Union; and a seminar on of "espressing opinions aimed at have included Dr. Khmara's release as fifth anniversary of the Chornobyl "The Humanitarian Aspects of the creating a negative impression among one of their demands, view this case as a nuclear disaster and raise funds for its Chornobyl Catastrophe" to be held the public of the judicial system, which political set-up to silence this radical victims. concurrently with the hearings by will create obstacles to the normal opposition leader in today's Ukrainian Citizens of Ukraine, various organi­ Zelenyi Svit and the Ukrainian Peace disposition of his case." Supreme Soviet. zations in the republic and individuals Committee. As The Weekly was going to press, from throughout the world are invited Also during Chornobyl Week in Thus, the lawyers add, this rearrest of no news was available on the state to participate in the action by contri­ Ukraine, there will be what is billed as a Dr. Khmara can be viewed as a punish­ of Dr. Khmara's health. buting to a special fund set up at the "Rock Requiem," organized by the Kiev branch of the Foreign Economic Kiev City Council and Zelenyi Svit; a Bank of the USSR (Account No. conference on alternative energy sources 000700620 MFO 805119). For informa­ whose main sponsoV is Zelenyi Svit; and Khmara, at press conference, tion, interested persons may call 228-25- a conference on "The Chornobyl Ques­ 34 in Kiev; or contact the tele-radio- tion: A Global View," sponsored by the thon organizers via fax, 228-28-89, or Chornobyl Union and the Ukrainian demonstrates fighting spirit telex, 131359 Radio, also in Kiev. Academy of Sciences. (Permanent Mission of the Ukrainian April 26 has been designated a day of by Marta Kolomayets nid Berezansky and Oleh Batovkin, SSR to the United Nations) national mourning. Church services will Kiev Press Bureau who were arrested with him and be held throughout Ukraine, as will remain imprisoned at Lukianivske. demonstrations and vigils. Citizens of KIEV - "The striking miners arfe People's Deputy Khmara also ф KIEV - The 29-year-old son of Ukrainian SSR Supreme Soviet Vice- Ukraine are being asked to place can­ on the front line in the struggle to stated: dles in the windows of their homes in build an independent state," said ^ Those who had participated in Chairman Ivan Pliushch was found murdered in his Kiev apartment on commemoration of the Chornobyl Deputy Stepan Khmara, five days the Supreme Court's decision were tragedy. (ECOLOS) after his release from the Lukianivka motivated not by the law or justice, April 13. According to unofficial re­ Prison. but acted in keeping with traditional ports, Valeriy Pliushch was found dead ^ MUNICH - As of January 1, During a press conference or­ totalitarian practice. of multiple stab wounds. There were no there were nearly 10,000 registered reli­ ganized by Rttkh and the National ь The so-called criminal case signs of burglary.
Load more

Recommended publications
  • FA Family News 3/01
    FAMILY NEWSLETTER #29 A Semi-annual Newsletter on Fanconi Anemia for Families, Physicians, and Research Scientists Spring 2001 Researchers, treating physicians, and FA parents attended the FA Scientific Symposium in October. HIGHLIGHTS Fanconi Anemia Plan to Attend August Scientific Symposium Family Meeting! Discoveries Reported...................2 One hundred fifty-six researchers, Our 10th annual FA Family Meet- Gene Therapy Trial to Begin.......2 treating physicians, and fifteen FA par- ing is seven months away, but now is ents from fourteen countries met in the time to start planning. This year, Bone Marrow Transplant Conference Planned .................2 Amsterdam for the Twelfth Annual we will offer a limited number of schol- International FA Scientific Sympo- arships to help families defray travel Comparison Between sium, October 26-29, 2000. Coun- and lodging expenses (see article, p. 11). Complementation Group and Mutations, and Clinical tries represented were Tunisia, France, From August 10-14, 2001, FA fam- Outcomes...................................3 England, Canada, Spain, Italy, Ger- ilies, treating physicians, and research- many, Argentina, Israel, Japan, South ers will meet at the picturesque lake- Fludarabine-Based Regimen for Alternate Donor Hemato- Africa, Russia, The Netherlands and front setting of Aurora University’s poietic Cell Transplantation....4 the United States. Fifty-one scientists George Williams Lake Geneva cam- and treating physicians gave formal pus in Williams Bay, Wisconsin. We New Promising Vectors for presentations. Evaluations from atten- will learn from our experts, meet and Gene Therapy ............................4 dees confirmed, once again, that our share experiences with other FA fam- Preimplantation Genetic annual scientific meeting is an out- ilies, and relax.
    [Show full text]
  • International Journal of Pediatrics and Neonatal Health, 2 (1)
    Twenty-seven years of controversy: The perils of PGD Item Type Article Authors Cherkassky, Lisa Citation Cherkassky, L. (2018) 'Twenty-seven years of controversy: The perils of PGD', International Journal of Pediatrics and Neonatal Health, 2 (1). Publisher BioCore Journal International Journal of Pediatrics and Neonatal Health Download date 25/09/2021 21:30:55 Link to Item http://hdl.handle.net/10545/622151 Lisa Cherkassky (2017). Twenty-Seven Years of Controversy: The Perils of PGD. Int J Ped & Neo Heal. 1:6, International Journal of Pediatrics and Neonatal Health ISSN 2572-4355 Review Article Open Access Twenty-Seven Years of Controversy: The Perils of PGD Lisa Cherkassky Senior Lecturer in Law, Derby Law School , University of Derby, UK *Corresponding Author: Lisa Cherkassky, Senior Lecturer in Law, Derby Law School , University of Derby, UK, Tel: 01332 591806, E-Mail: [email protected] Citation: Lisa Cherkassky (2017). Twenty-Seven Years of Controversy: The Perils of PGD. Int J Ped & Neo Heal. 1:6, Copyright: © 2017 Lisa Cherkassky. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Received November 28, 2017 ; Accepted December 08, 2017 ; Published XXXX, 2017. Abstract It has been 27 years since the Human Fertilisation and Embryology Act 1990 was passed in the United Kingdom in response to advances in fertility treatment. Preimplantation genetic diagnosis - the screening of embryos for genetic diseases - has led to lengthy ethical de- bates on sex selection, eugenics, disabilities, saviour siblings, surplus embryos and most recently, adult-onset diseases (the BRCA cancer gene).
    [Show full text]
  • Genetic Testing
    GENETIC TESTING The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 13 July 2001 Edited by D A Christie and E M Tansey Volume 17 2003 CONTENTS Illustrations v Introduction Professor Peter Harper vii Acknowledgements ix Witness Seminars: Meetings and publications xi E M Tansey and D A Christie Transcript Edited by D A Christie and E M Tansey 1 References 73 Biographical notes 91 Glossary 105 Index 115 ILLUSTRATIONS Figure 1 Triploid cells in a human embryo, 1961. 20 Figure 2 The use of FISH with DNA probes from the X and Y chromosomes to sex human embryos. 62 v vi INTRODUCTION Genetic testing is now such a widespread and important part of medicine that it is hard to realize that it has almost all emerged during the past 30 years, with most of the key workers responsible for the discoveries and development of the field still living and active. This alone makes it a suitable subject for a Witness Seminar but there are others that increase its value, notably the fact that a high proportion of the critical advances took place in the UK; not just the basic scientific research, but also the initial applications in clinical practice, particularly those involving inherited disorders. To see these topics discussed by the people who were actually involved in their creation makes fascinating reading; for myself it is tinged with regret at having been unable to attend and contribute to the seminar, but with some compensation from being able to look at the contributions more objectively than can a participant.
    [Show full text]
  • Over a Decade of Experience with Preimplantation Genetic Diagnosis a Multicenter Report
    FERTILITY AND STERILITY௡ VOL. 82, NO. 2, AUGUST 2004 CONTROVERSY: PREIMPLANTATION Copyright ©2004 American Society for Reproductive Medicine Published by Elsevier Inc. GENETIC DIAGNOSIS Printed on acid-free paper in U.S.A. Over a decade of experience with preimplantation genetic diagnosis: a multicenter report Yury Verlinsky, Ph.D.,a Jacques Cohen, Ph.D.,b Santiago Munne, Ph.D.,b Luca Gianaroli, M.D.,c Joe Leigh Simpson, M.D.,d Anna Pia Ferraretti, M.D.,c and Anver Kuliev, M.D., Ph.D.a Reproductive Genetics Institute, Chicago, Illinois; Saint Barnabas Medical Center, West Orange, New Jersey; and Societa Italiana Stukli di MEdicina della Reproduzione (SISMER), Bologna, Italy Objective: To review a 12-year experience of the world’s three largest preimplantation genetic diagnosis (PGD) centers. Design: Multicenter analysis of the clinical outcome of PGD. Setting: In vitro fertilization programs at the Reproductive Genetics Institute, Chicago, Illinois; Saint Barnabas Medical Center, West Orange, New Jersey; and SISMER, Bologna, Italy. Patient(s): Poor-prognosis IVF patients, patients carrying balanced chromosomal translocations, and couples at risk for producing children with Mendelian disorders. Intervention(s): In vitro fertilization, intracytoplasmic sperm injection, polar body removal, blastomere biopsy, and ET. Main Outcome Measure(s): DNA or chromosomal analysis of biopsied polar bodies or blastomeres, implantation and clinical pregnancy rates, and live-born pregnancy outcome. Result(s): A total of 754 babies have been born as a result of 4,748 PGD attempts, which shows the expanded application and the practical relevance of PGD for single-gene disorders, chromosomal aneuploidies and translocations, late-onset diseases with genetic predisposition, and nondisease testing in couples at need for human leukocyte antigens-matched offspring for treatment of affected siblings.
    [Show full text]
  • Preimplantation Diagnosis: a Realistic Option for Assisted Reproduction and Genetic Practice Anver Kuliev and Yury Verlinsky
    Preimplantation diagnosis: a realistic option for assisted reproduction and genetic practice Anver Kuliev and Yury Verlinsky Purpose of review Introduction Preimplantation genetic diagnosis (PGD) allows genetically Introduced 14 years ago, preimplantation genetic diag- disadvantaged couples to reproduce, while avoiding the nosis (PGD) permits genetic testing before the transfer of birth of children with targeted genetic disorders. By embryos to the mother, which has distinct advantages in ensuring unaffected pregnancies, PGD circumvents the establishing pregnancies unaffected by tested disorders possible need and therefore risks of pregnancy termination. and without the potential need for pregnancy termina- This review will describe the current progress of PGD for tion. Approximately 7000 PGD cases have been per- Mendelian and chromosomal disorders and its impact on formed worldwide, which have resulted in the birth of reproductive medicine. more than 1000 healthy children [1]. PGD can be used Recent findings for the diagnosis of late-onset diseases with genetic Indications for PGD have expanded beyond those used in predisposition, preimplantation HLA typing, and other prenatal diagnosis, which has also resulted in improved non-traditional prenatal testing; thus, PGD complements access to HLA-compatible stem-cell transplantation for other methods used in prenatal diagnosis [2]. By permit- siblings through preimplantation HLA typing. More than ting selection of euploid embryos for transfer, PGD 1000 apparently healthy, unaffected children have been improves reproductive outcome, which has resulted in born after PGD, suggesting its accuracy, reliability and its extensive use in assisted reproduction practices [1, safety. PGD is currently the only hope for carriers of 2–5]. This review will describe the current progress of balanced translocations.
    [Show full text]
  • Genetic Testing (V19) 3/11/03 8:46 Pm Page I
    Genetic Testing (v19) 3/11/03 8:46 pm Page i GENETIC TESTING The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 13 July 2001 Edited by D A Christie and E M Tansey Volume 17 2003 ©The Trustee of the Wellcome Trust, London, 2003 First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2003 The Wellcome Trust Centre for the History of Medicine at UCL is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 085484 094 6 All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/ Please cite as: Christie D A, Tansey E M. (eds) (2003) Genetic Testing. Wellcome Witnesses to Twentieth Century Medicine, vol. 17. London: Wellcome Trust Centre for the History of Medicine at UCL. Key Front cover photographs, top to bottom: Professor Marcus Pembrey Dr Patricia Tippett Professor Doris Zallen Professor Sir David Weatherall, Professor Charles Rodeck Inside front cover photographs, top to bottom: Professor John Woodrow Professor Rodney Harris Professor John Edwards (1928–2007) Professor Sue Povey Back cover photographs, top to bottom: Professor Ursula Mittwoch Professor Malcolm Ferguson-Smith Professor Matteo Adinolfi Professor Paul Polani (1914–2006) Inside back cover photographs, top to bottom: Professor Matteo Adinolfi, Professor Paul Polani (1914–2006) Professor Paul Polani (1914–2006), Professor Rodney Harris Professor Bernadette Modell Mrs Cathy Holding, Professor Alan Handyside Genetic Testing (v19) 3/11/03 8:46 pm Page iii CONTENTS Illustrations v Introduction Professor Peter Harper vii Acknowledgements ix Witness Seminars: Meetings and publications xi E M Tansey and D A Christie Transcript Edited by D A Christie and E M Tansey 1 References 73 Biographical notes 91 Glossary 105 Index 115 Genetic Testing (v19) 3/11/03 8:46 pm Page iv Genetic Testing (v19) 3/11/03 8:46 pm Page v ILLUSTRATIONS Figure 1 Triploid cells in a human embryo, 1961.
    [Show full text]
  • Preimplantation HLA Testing
    ORIGINAL CONTRIBUTION Preimplantation HLA Testing Yury Verlinsky, PhD Context Preimplantation genetic diagnosis (PGD) has become an option for couples Svetlana Rechitsky, PhD for whom termination of an affected pregnancy identified by traditional prenatal di- agnosis is unacceptable and is applicable to indications beyond those of prenatal di- Tatyana Sharapova, MS agnosis, such as HLA matching to affected siblings to provide stem cell transplanta- Randy Morris, MD tion. Mohammed Taranissi, MD Objective To describe preimplantation HLA typing, not involving identification of a causative gene, for couples who had children with bone marrow disorders at need for Anver Kuliev, MD, PhD HLA-matched stem cell transplantation. REIMPLANTATION GENETIC DIAG- Design, Setting, and Participants HLA matching procedures conducted at a single nosis (PGD) has become avail- site during 2002-2003 in an in vitro fertilization program for 9 couples with children able as an alternative to prena- affected by acute lymphoid leukemia, acute myeloid leukemia, or Diamond-Blackfan anemia requiring HLA-matched stem cell transplantation. In 13 clinical cycles, DNA in tal diagnosis in order to avoid single blastomeres removed from 8-cell embryos following in vitro fertilization was Pthe risk for pregnancy termination, be- analyzed for HLA genes simultaneously with analysis for short tandem repeats in the cause PGD allows selection of unaf- HLA region to select and transfer only those embryos that were HLA matched to fected embryos before a pregnancy is es- affected siblings. tablished. Despite the need for ovarian Main Outcome Measures Results of HLA matching and pregnancy outcome. stimulation and in vitro fertilization (IVF) to be part of the procedure, PGD Results As a result of testing a total of 199 embryos, 45 (23%) HLA-matched em- bryos were selected, of which 28 were transferred in 12 clinical cycles, resulting in 5 has become an acceptable method for singleton pregnancies and birth of 5 HLA-matched healthy children.
    [Show full text]
  • PREIMPLANTATION GENETIC DIAGNOSIS and PARENTAL PREFERENCES: BEYOND DEADLY DISEASE Susannah Baruch, J.D.*
    BARUCH 2-14.DOC 2/17/2009 5:28 PM 8 HOUS. J. HEALTH L. & POL’Y 245-270 245 Copyright © 2008 Susannah Baruch, Houston Journal of Health Law & Policy. ISSN 1534-7907 PREIMPLANTATION GENETIC DIAGNOSIS AND PARENTAL PREFERENCES: BEYOND DEADLY DISEASE Susannah Baruch, J.D.* I. Introduction .................................................................................................. 245 II. What is Preimplantation Genetic Diagnosis? .............................................. 247 III. Beyond Deadly Disease: Four Additional Ways Prospective Parents use PGD. .......................................................................................................... 251 A. HLA Matching to Save an Older Child ............................................ 253 B. Adult Onset Diseases........................................................................ 253 C. Non-Medical Sex Selection .............................................................. 253 D. Selection for a Disability.................................................................. 254 IV. PGD and Ethics.......................................................................................... 256 V. PGD Oversight............................................................................................ 261 VI. A Proposal for PGD Oversight in the United States. ................................. 267 VII. Conclusion................................................................................................ 270 I. INTRODUCTION Preimplantation genetic diagnosis (PGD) is the genetic
    [Show full text]
  • The Ukrainian Weekly 1991, No.16
    www.ukrweekly.com їкЬей by the Ukrainian National Association Inc., a fraternal non-profit association! rainian WeeklУ Vol. LIX Ш THE UKRAINIAN WEEKLY SUNDAY, APRIL 21,1991 50 cents No. 16 Scientist says Chornobyl Miners, workers protest in Kiev claimed 10,000 lives Republican strike leader is arrested JERSEY CITY, N.J. - Vladimir explosion and that, "Three months ago by Marta Koiomayets arrived from all coal-producing regions Chernousenko, the scientific director in one of the people who participated in Kiev Press Bureau in Ukraine - from Volyn to Luhanske charge of the 20-mile exclusion zone limiting the damage of the accident died — on April 15 and 16 to demand that surrounding the Chornobyl nuclear in Kiev." KIEV - Dmytro Poyizd, the legal their government guarantee them and consultant for the newly formed the citizens of their republic a better power plant, said that the Chornobyl He further stated that "Some of the disaster claimed between 7,000 and Republican Strike Committee, was future — a future that includes free­ people involved in limiting the damage arrested early in the morning on Thurs­ dom for Ukraine. 10,000 lives, far more than the Soviet to Chornobyl received (radiation) doses government's official figures, reported day, April 18, just hours after he Angered upon learning the fate of one above the maximum...in fact 145 people organized a miners' and workers' sit-in of their leaders, the miners began the April 14 edition of the British came down with acute radiation newspaper Independent on Sunday. along the Khreshchatyk boulevard, planning anew strategy on Thursday sickness." Other scientists contacted at reported Bohdan Ternopilsky, vice- morning.
    [Show full text]
  • Extracellular Matrix Stiffness and Geometry: the Impact on Static and Dynamic Cellular Systems in Vitro and the Treatment of Tissue Ischemia
    EXTRACELLULAR MATRIX STIFFNESS AND GEOMETRY: THE IMPACT ON STATIC AND DYNAMIC CELLULAR SYSTEMS IN VITRO AND THE TREATMENT OF TISSUE ISCHEMIA BY ARTEM A. SHKUMATOV DISSERTATION Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in VMS-Veterinary Pathobiology in the Graduate College of the University of Illinois at Urbana-Champaign, 2014 Urbana, Illinois Doctoral Committee: Assistant Professor Hyunjoon Kong, Chair Professor Marie-Claude Hofmann Professor Mark S. Kuhlenschmidt Professor Matthew Wallig Abstract Biologically relevant cell culture assays that can be adapted for high-throughput screening are very important for biopharmaceutical industry. Cellular material for such applications can represent static cultures that do not change over time, or dynamic (i.e. transformational) cultures based on pulripotent cells undergoing “cellular metamorphosis” and differentiating into a multitude of various descendant cell types – the process accompanied by formation of histologically complex tissues. Hydrogels being hydrophilic polymer-based adhesion matrices promote tissue-like microenvironments through tunable mechanical qualities and presentation of bioactive molecules. Moreover, hydrogel-based implants with controlled geometry can also be used for stem cell delivery and other therapeutic applications. This thesis investigates how main cell functions can be controlled by the matrix mechanical properties, with a goal to emulate physiological processes in vitro and potentiate stem cell treatments with appropriate bio-matrix design. First, I describe a method to promote advanced cardiomyogenic and endothelial differentiation within embryoid bodies through the control of three-dimensionality on collagen-polyacrylamide gels with tunable stiffness (Chapter 2). Next, the function of airway smooth muscle cells is investigated on substrates with physiological and pathological stiffnesses as it pertains to the cell adhesion, proliferation, calcium signaling and secretory function (Chapter 3).
    [Show full text]
  • Materials Submitted to NIH from Reproductive Genetics Institute (RGI) Submissions #2009-ACD-006 & 2009-ACD-007
    Materials Submitted to NIH From Reproductive Genetics Institute (RGI) Submissions #2009-ACD-006 & 2009-ACD-007 (Both submissions have the same supporting documentation) I. Submission Cover Page (2009-ACD-006) p.l II. Submission Cover Page (2009-ACD-007) p. 11 III. Letter from RGI President p. 19 IV. Description of Supporting Information p. 20 V. Investigational Review Board Approval p. 25 VI. Research Consent p. 26 VII. Assurance Documents p. 31 VIII. Publications p. 38 IX. IIB Assurance p. 56 X. Additional Information: • Other Details via Email Correspondence p. 58 • IVF Clinical Consent (Couple A) p. 60 • Cryopreservation Consent (Couple A) p. 64 • Research Consent with Dates for Couple A; p. 69 (Document text is identical to Item VI, p. 26) • IVF Clinical Consent (Couple B) p. 74 • Research Consent with Dates for Couple B; p. 78 (Document text is identical to Item VI, p. 26) • Other Details via Email Correspondence p. 83 • Other Details via Email Correspondence p. 86 NOTE: Duplicative information in the submission is not included. Table of Clinical IVF and Research Consent Dates not included to protect patient privacy. List Page -hESC Registry Application Database Page 1 of 10 hESC Registry Application Database Detailed Listing for Request #: 2009-ACD-006 April 21, 2010 hESC Registry Application Search Results Request #: 2009-ACD-006 Organization: Reproductive Genetics Institute Status: Pending Org Address: 2825 North Halsted St., Chicago, IL 60657 USA DUNS: 790373369 Grant Number(s): n/a Review: ACD Signing Official (SO): Verlinsky
    [Show full text]
  • Implications of Genetic Testing for Health Policy
    Yale Journal of Health Policy, Law, and Ethics Volume 10 Issue 1 Yale Journal of Health Policy, Law, and Article 2 Ethics 2010 Implications of Genetic Testing for Health Policy Gregory Katz Stuart O. Schweitzer Follow this and additional works at: https://digitalcommons.law.yale.edu/yjhple Part of the Health Law and Policy Commons, and the Legal Ethics and Professional Responsibility Commons Recommended Citation Gregory Katz & Stuart O. Schweitzer, Implications of Genetic Testing for Health Policy, 10 YALE J. HEALTH POL'Y L. & ETHICS (2010). Available at: https://digitalcommons.law.yale.edu/yjhple/vol10/iss1/2 This Article is brought to you for free and open access by Yale Law School Legal Scholarship Repository. It has been accepted for inclusion in Yale Journal of Health Policy, Law, and Ethics by an authorized editor of Yale Law School Legal Scholarship Repository. For more information, please contact [email protected]. Katz and Schweitzer: Implications of Genetic Testing for Health Policy Implications of Genetic Testing for Health Policy Gregory Katz* and Stuart 0. Schweitzert INTRODUCTION ............................................................................................... 92 I. THE DIFFUSION OF GENETIC TESTING AND ITS IMPACT ON MEDICAL PRACTICES ...................................................................................................... 93 A. MEDICAL PRACTICES AND NATIONAL DISPARITIES ................................ 94 B . ONLINE D ISTRIBUTION ...........................................................................
    [Show full text]