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7. Clear Cell Acanthoma

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7. Clear Cell Acanthoma Listy do Redakcji / Letters to the Editor CLEAR CELL ACANTHOMA – OPIS PRZYPADKU CASE REPORT OF CLEAR CELL ACANTHOMA Brzezi ński Piotr 6 Wojskowy Oddział Gospodarczy, Ustka, Polska 6th Military Support Unit, Ustka, Poland, [email protected] N Dermatol Online. 2010; 1(2): 29-30 Acanthoma clarocellulare (ACC) wyst ępuje Clear cell acanthoma (CCA) is characterized by jako pojedynczy, ró żowo-br ązowy guzek i zwykle pink-brown nodules and usually occurs on the legs of zlokalizowany jest na ko ńczynie dolnej u osób starszych. elderly people. ACC został po raz pierwszy opisany przez Degosa jako CCA was first described by Degos as a benign tumor of łagodny nowotwór pochodzenia nabłonkowego. ACC epidermal origin. Clear cell acanthoma are also known as wyst ępuje równie ż pod innymi nazwami: Degos Degos acanthoma, tumor Degos or acanthome à cellules acanthoma, guz Degosa czy acanthome à cellules claires. Some authors have also suggested that it is a claires. localized form of inflammatory psoriasiform dermatoses. Niektórzy autorzy sugeruj ą, że jest to forma The diagnosis is rarely made before skin biopsy. When zlokalizowanego łuszczycopodobnego zapalenia skóry. examined under the microscope, clear cell acanthoma Diagnoza jest rzadko stawiana przed otrzymaniem show a characteristic accumulation of clear glycogen- wyniku biopsji skóry. W badaniu pod mikroskopem, containing cells in the epidermis. The common wida ć jasne komórki, które wykazuj ą cechy kumulacji i dermatoscopic feature of all these articles is the presence zawieraj ą glikogen. Charakterystyczn ą cech ą w obrazie of pinpoint-like/dotted vessels, which are described as dermoskopowym jest obecno ść tzw. pinpoint-like/dotted having a homogenous/bunch-like, reticular, pearl vesseles, które s ą opisane jako homogenne, podobne do lessions. So far, only a few cases presented the pęków, siatkowate, perłowe zmiany. Jak dot ąd tylko dermoscopy analysis of ACC. kilka przypadków ACC zostało poddanych analizie A 45 year-old woman presented with a 4-year dermatoskopowej. history of a lesion on the posterior aspect of his leg (fig. Do Ambulatorium zgłosiła si ę 45-letna kobieta 1). Dermatological examination revealed a red-brown, ze zmian ą na ko ńczynie dolnej lewej, która pojawiła si ę vascularized lession and central squaming with a cztery lata wcze śniej na zgi ęciowej stronie ko ńczyny diameter of 1,5 x 2 cm. Dermatoscopy disclosed multiple dolnej (ryc.1). dotted vessels arranged partly in a linear and partly in a reticular appearance (fig. 2). Characteristics include of CCA: asymptomatic course, slow growth, single, pink- brown nodules or small plaques often located in the lower extremities of elderly patients and the dermoscopy image. Characteristic features of CCA also occurred in the analyzed patient.Irritated seborrheic keratose, basal- cell carcinoma, Bowen's disease, squamous-cell carcinoma, keratoacanthoma and amelanotic melanoma or nodular melanoma should be considered in the differential diagnosis of CCA. Figure. 1 Nodule on the leg © N Derma tol Online 2.2010 29 Badanie dermatologiczne wykazało, czerwono-br ązow ą, unaczynion ą zmian ę z centralnie poło żon ą łusk ą o średnicy 1,5 x 2 cm. Dermatoskopia ujawniła wiele czerwonych kropek umieszczonych cz ęś ciowo w sposób liniowy, a cz ęś ciowo skupionych, o siatkowatym charakterze (ryc. 2). Do charakterystycznych cech ACC mo żna zaliczy ć: bezobjawowy przebieg, powolny wzrost, pojedynczy ró żowo-br ązowy guzek lub małe ognisko o twardej konsystencji, zwykle znajduj ący si ę na ko ńczynach dolnych u pacjentów w podeszłym wieku oraz obraz dermoskopowy. Charakterystyczne cechy ACC wyst ępowały równie ż w analizowanym przypadku. Zmian ę skórn ą nale ży jednak ró żnicowa ć z brodawk ą łojotokow ą, rakiem podstawnokomórkowym, chorob ą Figure. 2 Clear cell acanthoma in dermoscopy Bowena, rakiem płaskonabłonkowym rogowaciej ącym, rogowiakiem kolczystokomórkowym, amelanotycznym czerniakiem lub czerniakiem guzkowym. 30 © N Dermatol Online 2.2010 .
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