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Ilk Sayfalar 7/6/04 14:13 Page 1 ANDROLOJ‹ BÜLTEN‹ ilk sayfalar 7/6/04 14:13 Page 1 ANDROLOJ‹ BÜLTEN‹ TÜRK ANDROLOJ‹ DERNE⁄‹ YAYIN ORGANIDIR Türk Androloji Derne¤i Cemil Aslan Güder Sok. ‹dil Ap. B Blok D.1 80280 Gayrettepe, ‹stanbul Tel: 0212 288 50 99 Faks: 0212 288 50 98 E-posta: [email protected] Web: www.androloji.org.tr TÜRK ANDROLOJ‹ DERNE⁄‹ ADINA SAH‹B‹ Prof. Dr. Atefl Kad›o¤lu GENEL YAYIN YÖNETMEN‹ Uz. Dr. Memduh Ayd›n REDAKTÖR Uz. Dr. Ertan Sakall› YÖNET‹M KURULU Atefl Kad›o¤lu (Baflkan) Bülent Semerci (Genel Yazman) ‹rfan Orhan (Sayman) Ramazan Aflç› (Üye) M. Önder Yaman (Üye) Selahittin Çayan (Üye) Mustafa F. Usta (Üye) Nisan 2004 Say› 17 2 Ayda Bir Yay›nlan›r ilk sayfalar 7/6/04 14:14 Page 2 GENEL YAYIN YÖNETMENİ REDAKTÖR Uz. Dr. Memduh Aydın Uz. Dr. Ertan Sakallı BİLİMSEL KURUL ERKEK CİNSEL SAĞLIĞI Yaşlılık ve Cinsellik Ejakülasyo PrekoksRekonstrüktif Cerrahi ED ve Farmakoterapisi Doç. Dr. Ali Atan Prof. Dr. Ahmet Metin Prof. Dr. Erdal Apaydın Uz. Dr. Ertan Sakallı Uz. Dr. Melih Beysel Temel Araştırma Psikolojik ED Doç. Dr. Emin Özbek Yrd. Doç. Dr. Hakan Kılıçarslan Yrd. Doç. Dr. Mustafa Faruk Usta Doç. Dr. Doğan Şahin INFERTİLİTE Varikosel Endokrinoloji Doç. Dr. Selahittin Çayan Uz. Dr. Necati Gürbüz Doç. Dr. Turhan Çaşkurlu Doç. Dr. İsa Özbey Yardımla Üreme Teknikleri Genetik Prof. Dr. Kaan Aydos Doç. Dr. Barış Altay Uz. Dr. Lütfi Tunç Uz. Dr. A. Arman Özdemir Yrd. Doç. Dr. Murat Şamlı Obstrüktif İnfertilite Kadın İnfertilitesi Doç. Dr. Hamdi Özkara Doç. Dr. İrfan Orhan Prof. Dr. Cihat Ünlü Doç. Dr. Erkut Attar Pediatrik Androloji Androloji Laboratuarı Doç. Dr. Tarkan Soygur Yrd. Doç. Dr. Kenan Karademir Yrd. Doç. Dr. Engin Kandıralı Kim. Gülşen Aktan II ilk sayfalar 7/6/04 14:14 Page 3 KADIN CİNSEL SAĞLIĞI Yrd. Doç. Dr. Sezgin Güvel Yrd. Doç. Dr. Ercan Yeni Doç. Dr. Bülent Alıcı Kadın - Erkek Cinsel Sağlığı ve Erkek İnfertilitesi Hemşire Çalışma Grubu Cerrahi Hastalıklar Kardiyolojik Hastalıklar Psikiyatri MSc. Dilek Aygin MSc. Hicran Yıldız Doç. Dr. Sevim Buzlu MSc. Leyla Küçük Kadın Hastalıkları ve Doğum Diyabet Prof. Dr. Hediye Aslan Doç. Dr. Nezihe Kızılkaya Beji Doç. Dr. Rukiye Pınar Yrd. Doç. Dr. Şeyda Özcan Nöroloji Onkolojik Hastalıklar Ergen Cinselliği ve Cinsel Eğitim MSc. Zeynep Kurtuluş Dr. Gülbeyaz Can MSc. Birsen Küçük Dikencik MSc. Tülay Yılmaz TÜRKİYE’DEKİ ANDROLOJİ YAYINLARI VE KONGRE TAKVİMİ BİR PORTRE Doç. Dr. Murad Başar Uz. Dr. Memduh Aydın Yay›nc› S›racevizler Cad. 43/3 Tel. : (0212) 219 49 00 Küre ‹letiflim Grubu A.fi. fiiflli 34381 ‹stanbul Faks: (0212) 230 50 09 www.kure.com.tr ∞ Bu yayında ISO 9706: 1994 (Requirements for Permanence) uluslararası standartlarına uygun olarak asitsiz kağıt kullanılmıştır. This publication is printed on acid-free paper that meets the international standart ISO 9706: 1994 (Requirements for Permanence). III ilk sayfalar 7/6/04 14:14 Page 4 YAZIM KURALLARI 1. Androloji Bülteni, Türk Androloji Derne¤i'nin resmi yay›n organ› olup, iki ayda bir yay›nlan›r. 2. Bültenin amac›, erkek ve kad›n cinsel sa¤l›¤›, erkek infertiltesinde sürekli bilgi ak›fl›n› sa¤lamakt›r. Bültende kongre ve konferans bildiri özetleri, literatür özetleri ve derlemeler yay›nlan›r. Derlemeler 4 sayfay›, literatür özetleri 1 say- fay› aflmayacak flekilde haz›rlanmal›d›r. 3. Yay›n için yaz› gönderen yazarlar, yaz›lar›n çeviri içeri¤inden sorumludurlar. 4. Bültene gönderilen yaz›lar, anlam ve yaz›m kurallar› yönünden incelenecektir. Yay›n kurulu yaz›larda düzenlemeler yapabilecektir. 5. Bültene gönderilecek güncel makale özetlerinin ak›c› bir çeviri ile Türk Dil Kurumu Türkçe sözlü¤ü ve Yaz›m Kuralla- r›na uygun olarak yaz›lmas› gereklidir. Yaz›larda bilimsel içeri¤i bozmayacak flekilde k›saltmalar ve düzeltmeler yap- ma hakk› yay›n kuruluna aittir. 6. Yaz›da kullan›lan tablolar numaraland›r›lmal›, bafll›k içermeli, tablo alt›nda gerekli aç›klama yap›lmal›, yaz› içindeki yerleri belirtilmelidir. 7. Sadece standart k›saltmalar kullan›lmal›d›r. Bafll›kta k›saltma kullan›lmamal›d›r. K›saltma standart bir ölçüm birimine ait de¤ilse, metinde ilk kullan›ld›¤› yerin önünde k›saltman›n ait oldu¤u tam terim bulunmal›d›r. 8. Derlemelerde kaynaklar, metinde geçifl s›ras›na göre numaraland›r›lmal›d›r ve NLM nin ‘Index Medicus’ta kulland›- ¤› format esas al›narak haz›rlanm›fl afla¤›daki örnek stiller kullan›lmal›d›r. 1. Dergiler: 1) Yazar›n soyad› ve isimlerinin bafl harfleri (nokta); 2) Yaz›n›n bafll›¤› (ilk harf d›fl›nda tamamen küçük harfle) (nokta); 3) Derginin ad› veya Index Medicusa'a göre k›salt›lm›fl flekli; 4) Yay›nland›¤› y›l (noktal› virgül); Cilt numaras› (arabik) (iki nokta üst üste ve boflluk); ‹lk sayfa (tire) son sayfa (nokta). Örnek: Levine LA, Estrada CR, Storm DW, Matkov TG. Peyronie disease in younger men: characteristics and treatment results.; J Androl. 2003 Jan- Feb;24(1):27-32. 2. Kitaplar: 1) Yazar›n ad› (nokta); 2) Kitab›n ad› (nokta); 3) (Varsa) kaç›nc› bask› oldu¤u (nokta); 4) Yay›nland›¤› fle- hir (Birkaç taneyse yaln›zca ilki) (virgül); 5) Yay›nevi (virgül); 6) Yay›nland›¤› y›l (noktal› virgül ve boflluk); 7) ‹lk say- fa (tire) son sayfa (nokta). Örnek: Culley Carson, Roger Kirby, Irwin Goldstein.; Textbook of Erectile Dysfunction Ox- fort, Isis Medical Media, 1999; 133-140. 3. Kongre bildileri: 1) Yazar›n soyad› ve isimlerinin bafl harfleri (nokta); 2) Yaz›n›n bafll›¤› (ilk harf d›fl›nda tamamen küçük harfle) (nokta); (3) Yay›nland›¤› bilimsel konferans; 4) Yay›nland›¤› y›l (noktal› virgül); Cilt numaras› (iki nokta üst üste ve boflluk); ‹lk sayfa (tire) son sayfa (nokta). Örnek: Culley Carson. American contributions to the treatment of erectile dysfunction. ISSIR 2002 / Montreal 26th September 2002;145 9. Güncel makale özetlerinde makale bafll›¤›n›n alt›na orijinal literatürün yazar›, yay›nland›¤› dergi y›l› ve dergideki say- fa numaras›; makale sonuna ise özetleyenin ad› - soyad›, çal›flt›¤› kurum belirtilmelidir. Orjinal literatürün kaynak for- mat›, Medline ile birebir olmal›d›r. 10. Editöre mektuplar, kaynaklarla birlikte 1 sayfay› aflmayacak flekilde yaz›lmal›d›r. 11. Yaz›lar Word for Windows format›nda, e-mail olarak [email protected] adresine gönderilmelidir. IV ilk sayfalar 8/6/04 11:55 Page 5 BAŞKANDAN MESAJ De¤erli Meslektafllar›m, Androloji Bülteni, ISSN (1304-6861) numaras›n› almas›n› takiben bu say› ile hakemli dergiler aras›nda yerini alm›flt›r. Dergiye gönderilen yaz›lar, bilimsel kurulda yer alan iki hakem taraf›ndan de¤erlendirilmekte ve nihai onay› takiben dergide yay›nlanmaktad›r. Bu üretilen veya derlenen bilginin bültende yay›nlanmas› belli oranda yazar›n akademik dosyas›na katk›da bulunacakt›r. Dernek, e¤itim politikas› çerçevesindeki etkinlikleriyle Haziran ay›nda en yo¤un dönemini yaflayacakt›r. Androlojide (Kad›n-Erkek Cinsel Sa¤l›¤› ve Erkek ‹nfertilitesi) Yenilikler ve Karmafl›k Vakalar›n Çözümü Sempozyumu ve kurslar sayesinde Androloji ile ilgilenen yüzlerce ürologla ulusal ve uluslararas› uzmanlar bilgi paylafl›m›nda bulunacakt›r. Temmuz ve A¤ustos aylar›nda dernek, 2004-2005 e¤itim bilim ve teknoloji politikas›n› belirleyerek sizlere ulaflt›racakt›r. Her say›da oldu¤u gibi bülten için çal›flmak isteyenlerin kat›l›m›n›n bizleri onurland›raca¤›n› yeniden vurgulamak isterim. Prof. Dr. Ateş Kadıoğlu V ilk sayfalar 8/6/04 11:55 Page 6 İÇİNDEKİLER Bölüm Editörleri . .II Yazım Kuralları . .IV Başkandan Mesaj . .V ERKEK CİNSEL SAĞLIĞI Derleme Peyronie hastalığının medikal tedavisindeki yenilikler Yrd. Doç. Dr. Abdullah Armağan, Yrd. Doç. Dr. Sedat Soyupek, Dr. M. Burak Hoşcan . .93 Korpus kavernozum elektromyografisinde tartışmalı noktalar ve yeni ufuklar Doç. Dr. Önder Kayıgil, Prof. Dr. Ahmet Metin . .99 Erektil disfonksiyon tedavisinde PDE5 inhibitörleri ve alternatif moleküller Op. Dr. Ertan Sakallı, Op. Dr. Memduh Aydın, Dr. Tuncer Şenkul . .101 Alt üriner sistem semptomları olan erkeklerde cinsel aktivitenin değerlendirilmesi Dr. Altuğ Tuncel, Doç. Dr. Ali Atan . .106 Güncel Makale Özeti Peyronie hastalığının cerrahi tedavisinde yeni bir yöntem: İntrakavernöz plak eksizyonu Çeviri: Prof. Dr. Ahmet Metin, Doç. Dr. Önder Kayıgil . .109 İatrojenik penil yaralanmalar ile ilgili 20 yıllık deneyim Çeviri: Dr. Zafer Tokatlı, Doç. Dr. Tarkan Soygür . .110 Enfekte penil implantlar için tedavi alternatifleri Çeviri: Doç. Dr. Bedrettin Seçkin . .111 Önceki sildenafil tedavisi başarısız olmuş hastalarda tedavinin tekrar denenmesi Çeviri: Op. Dr. Ergin Yücebaş . .113 Sildenafil sitrat QT intervallerini ve QT dispersiyonunu etkilememektedir: İlaç güvenliği açısından önemli bir gözlem Çeviri: Dr. Mete Alpaslan, Dr. Ersel Onrat, Dr. Çetin Dinçel, Yrd. Doç. Dr. Murat Şamlı . .114 Vardenafil’in proerektil etkisi: Tavşanlardaki in vitro çalışmalar ve sıçanlarda sildenafil ile in vivo karşılaştırılması Çeviri: Dr. Ahmet Özgür Güçtaş, Op. Dr. Memduh Aydın . .115 Tadalafil ve sildenafil arasında hasta tercihini değerlendirmek üzerine, çok merkezli, çapraz, çift kör bir çalışma Çeviri: Dr. Tuncer Şenkul, Op. Dr. Ertan Sakallı . .116 Erektil disfonksiyon tedavisinde tadalafil’in güvenilirlik ve toleransı Çeviri: Prof. Dr. Ahmet Metin, Doç. Dr. Önder Kayıgil . .117 Streptozotosin ile indüklenmiş diabetik ratlarda aminoguanidin’in erektil fonksiyon üzerindeki koruyucu etkisi Çeviri: Yrd. Doç. Dr. Çetin Yeşilli . .118 İskemik korpora dokusunda reperfüzyon: İskemik priapizmli hayvan modelinde fizyolojik ve biyokimyasal degişiklikler Çeviri: Dr. Rahmi Onur . .119 Kedilerde alprostadil ve SEPA (Topiglan) kombinasyonunun glans penise yüzeyel uygulanması ile penil ereksiyon oluşturulması Çeviri: Uz. Dr. Önder Cangüven, Doç. Dr. Selami Albayrak . .120 İNFERTİLİTE Derleme ICSI güvenilir bir uygulama mı? Dr. Murat Tezer, Dr. İlham Ahmedov, Prof. Dr. Ateş Kadıoğlu, Yrd. Doç. Dr. Engin Kandıralı . .121 Spermatogonial kök hücre nakli Androloji’nin yeni bir uğraş alanı Prof. Dr. Kaan Aydos . .126 Erkek inferilitesinde spermatogenezi etkileyen genetik faktörler Tıbbi Biyolog Bilge Özsait . .130 Yardımcı üreme tekniklerinin başarısında mitokondriyal ve nükleer sperm DNA incelemesinin önemi Doç. Dr. Barış Altay, Dr. Kaan Özdedeli . .134 TÜRKİYE’DEKİ ANDROLOJİ YAYINLARI . .138 KONGRE TAKVİMİ . .139 VI ilk sayfalar 8/6/04 14:06 Page 7 İÇİNDEKİLER İNFERTİLİTE’NİN DEVAMI Ovulasyon indüksiyonunda güncel yaklaşımlar Prof.
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