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Somerset CCG Quick Reference Formulary – First and Second Line Formulary Options Green is the CCG formulary preferred brand Blue is suitable for self care and available to buy OTC May 2021

Chapter 1 Gastro-intestinal system NICE guideline on chronic heart failure 2.8.2 Anticoagulants • Umeclidinium – Incruse NICE Guideline for reflux and 2.2 Diuretic NICE guideline on DVT Ellipta® • Emerade® dyspepsia • Indapamide • Enoxaparin LAMA/LABA Combination 3.7 Mucolytics 1.1 Dyspepsia and Reflux disease • Furosemide • Warfarin • Anoro Ellipta® or Duaklir • Carbocisteine Antacids • • DOACs – Dabigatran, Genuair® or Ultibro • Acetylcysteine as NACSYS® • Mucogel® • rivaroxaban, apixaban, Breezhale® or Spiolto Alginate 2.3 Aniti-arrhythmic edoxaban Respimat® Chapter 4 Central Nervous System • Peptac® • Amiodarone 2.9 Antiplatelets – prescribe by brand 4.1 Hypnotic and Anxiolytics • Acidex Advance® 2.4 Betablocker • Aspirin as Danamep®, • Theophylline MR – NHS Sleep and Tiredness guide 1.2 Antispasmodic • Bisoprolol clopidogrel, dipyridamole Uniphyllin Continus®, CCG hypnotics and anxiolytics • tabs • Atenolol MR, prasugrel, ticagrelor Nuelin SA® Hypnotics 1.3.5 PPI • Metoprolol 2.12 Lipid Regulating Drugs • Zoplidem, zopiclone, CCG PPI deprescribing algorithm 2.5.5 ACE-inhibitors Statins 3.2 (prescribe by diazepam • Lansoprazole, omeprazole, NICE guideline on hypertension • Atorvastatin, rosuvastatin, brand) NICE guideline on Anxiolytics pantoprazole, • Lisinopril Other lipid lowering corticosteroids in • Diazepam esomeprazole • Ramipril caps • • – MDI as 4.2 Antipsychotics 1.4 Acute diarrhoea ARBs Fibrates Sopradec® or Kelhale®, DPI • Risperidone, , NICE guideline for diarrhoea in under • Losartan • Fenofibrate micronized as Easyhaler® aripiprazole, 5s • Candesartan • - Easyhaler® • Quetiapine XL – Sondate • Dioralyte®, Loperamide Centrally acting antihypertensive Chapter 3 Respiratory System Combination Inhalers ICS/LABA XL®, Zaluron XL® 1.5 Chronic Bowel Disorders • Methyldopa NICE guideline on COPD • / 4.2.3 Antimanic drugs NICE guideline for colitis • Moxonidine CCG respiratory home page MDI as Combisal® or • Lithium – must be Prescribe mesalazine by brand Alpha-blocker CCG Venn Diagram AirFluSal®, DPI as prescribed by brand • Mesalazine 400mg as • Doxazosin - Doxadura® 3.1 Fusacomb Easyhaler® or 4.3 Antidepressants Zintasa EC®, 500mg as 2.6 Nitrates SABA Stalpex® SSRIs and Tricyclic Pentasa SR®, sachets as • GTN spray • CFC MDI • Budesonide/ • Fluoxetine, sertraline, Salofalk® • Isosorbide mononitrate • DPI - Salbutamol DPI as Fobumix® citalopram

1.6 Laxatives • Isosorbide mononitrate SR Easyhaler® Triple Combination LABA/LAMA/ICS • , NICE guideline for constipation – Tardisc XL®, Monomil LABA • /fluticasone • , venlafaxine Stimulants XL®, Chemydur XL® • Formoterol DPI – furoate/umeclidinium – • Venlafaxine MR – Vensir • Bisacodyl or senna or CCB - Dihydropyridines Easyhaler® DPI as Trelegy Ellipta® XL®, Venlalic XL®, Vencarm docusate, glycerol • • Formoterol MDI - Atimos® • Beclometasone/formoterol XL® suppositories • Lacidipine • Salmeterol – Soltel® or /glycopyrronium – MDI as 4.5.1 Obesity Osmotic • Lercanidipine Serevent Accuhaler® Trimbow® • Orlistat – P med can be • Macrogol - Laxido® or CCB – Rate limiting prescribe by brand • – Onbrez • /indacaterol/ bought Cosmocol® • Diltiazem MR – Zemtard Breezhaler® glycopyrronium DPI as 4.7 Analgesics Bulk forming Paracetamol prescribing guidelines XL®, Slozem® • – Striverdi Enerzair Breezhaler® • Ispaghula husk – Fybogel • Paracetamol • Verapamil Respimat® Spacer Devices • Lactulose Weak Opioids • Verapamil MR – Half- LAMA • EasyChamber® or 1.7 Anal and rectal disorders Securon SR® or Securon AeroChamber Plus® • Codeine Haemorrhoids & Anal Fissures • Ipratropium MDI SR® 3.3.2 Receptor • Co-codamol 30/500 – • Anusol or Scheriproct® • – Eklira 2.6.3 Potassium Channel Activator Antagonists Zapain® • GTN ointment -Rectogesic® Genuair® • Nicorandil • • – MR as Marol® • - Sinus Node Regulator 3.4.1 Antihistimes bd or Tradorec XL® od Chapter 2 Cardiovascular System Seebri Breezhaler® • Ivabradine • Non sedating – , Strong Opioids NICE guideline on strokes • Tiotropium -Braltus Zonda® 2.6.4 Vasodilators cetirizine • Morphine – Zomorph®, NICE guideline on atrial fibrillation or Spiriva Respimat® • Naftidrofuryl • Sedating - Morphgesic SR® Somerset CCG Quick Reference Formulary – First and Second Line Formulary Options Green is the CCG formulary preferred brand Blue is suitable for self care and available to buy OTC May 2021

• Fentanyl – Matrifen®, Chapter 6 Endocrine System Thiazolidinediones 5-ARIs • Ethinylestradiol / Fencino®, Mezolar® NHS diabetes guide • Pioglitazone • Finasteride – Levest®, • Buprenorphine – Bunov®, CCG diabetes page 6.5.2 Posterior pituitary hormones Maexeni®, Rigevidon® Reletrans®, Butec® 6.1.1 Insulins and Disposables DPP-4 inhibitors and antagonists • Ethinylestradiol/ Insulin must be prescribed by brand • Alogliptin • Desmopressin - Noqdirna® – Lizinna®, 4.7.3 Neuropathic Pain • Linagliptin, saxagliptin, Cilique® • Amitriptyline, duloxetine, Short acting sitagliptin, vildagliptin Chapter 6.6 – Drugs affecting Bone • Ethinylestradiol/ gabapentin, pregabalin • Aspart – Novorapid Rapid acting insulin secretagogue – Millinette® 30/75 4.7.4 Antimigraine • Lispro – Insulin Lispro • Repaglinide NICE advice on bisphosphonates • Ethinylestradiol/desogestr Acute Analgesia Sanofi® SGLT-2 inhibitor Patient guide to bisphosphonates el – Cimizt® 30/150, • Ibuprofen, paracetamol • Soluble – Human Actrapid, • Ertugliflozin, empagliflozin, Prevention of Munalea® 30/150, Anti-emetic Insuman Rapid, Humulin S dapagliflozin, canagliflozin • Alendronic acid, Gedarel® 30/150 • Domperidone - MHRA, Intermediate acting GLP-1 mimetic risedronate, ibandronate • Ethinylestradiol/drospireno metoclopramide - MHRA, • Biphasic isophane – • Lixisenatide Calcium with vitamin D – only if ne – Yacella® prochlorperazine Insuman Combe 15,25 & • Exenatide, liraglutide, bisphosphonate prescribed • Mestranol/ Triptans 50, Humulin M3 dulaglutide, semaglutide • Theical®, Accrete®, Adcal - Norinyl-1® • Sumatriptan, frovatriptan, • Biphasic insulin aspart – 6.2 Thyroid and Anti-thyroid drugs D3®, Evacal D3®, Calci-D® • Ethinylestradiol/ naratriptan, naratriptan NovoMix 30 Thyroid hormones Chapter 7 Obstetrics, Gynaecology norethisterone (tri phasic) - Prophylaxis • Biphasic Insulin lispro – • Levothyroxine and Urinary-tract Disorders Synphase® • Propranol, topiramate Humalog Mix 25 & 50 Anti-thyroid hormones 7.2 Treatment of Vaginal and Vulval • Ethinylestradiol / 4.10 Substance Dependence • Isophane insulin – Insuman • Carbimazole, Conditions levonorgestrel (tri phasic) – NHS Smokefree website Basal, Human Insulatard, propylthiouracil Atrophy TriRegol®, Logynon®, NICE guideline on stopping smoking in Humulin I 6.3 Corticosteroids • Estradiol – Ovestin®, Logynon® ED pregnancy Long acting • , Vagirux® 7.3.2Progesteron only contraceptives • NRT – patches, gum, • Insulin glargine – Fungal infections (POP) lozenge, spray Semglee®, Abasaglar, 6.4.1 Hormone Replacement Therapy • Fluconazole, • • Bupropion, varenicline Lantus Prescribe by brand 7.3 Contraceptives • Norethisterone – Noriday® Opioid Dependence • Insulin detemir – Levemir Unopposed oestrogen Methods of contraception • Levonorgestrel – • Methadone – Physeptone® • Insulin degludec – Tresiba • Elleste Solo®, Bedol®, Contraceptive pill suitable for patients Norgeston® • Buprenorphine sublingual Pen Needles and Lancets Evorel® taking hepatic enzyme-inducing drugs 7.3.2.3 Intra uterine POP tabs Compatibility chart Cyclical combined guideline • Mirena®, Jaydess®, 4.11 Drugs for Dementia • Microdot Max®, GlucoRx • Elleste Duet®, Clinorette®, FSRH guide to Drug Interactions with Levosert® Initiated by specialist only Carepoint®, GlucoRx Cyclo-progynova®, Evorel Hormonal Contraception Long acting reversible contraception AChE Inhibitors Carepoint Ultra® Sequi® 7.3.1 Combined hormonal • Medroxy- – • Donepezil • Microdot Plus®, Fastclix®, Continuous combined contraceptives Depo-Provera®, Sayana • Galantamine – MR as GlucoRx® • Kliofem®, Kliovance®, Low strength Press® Gatalin XL® or Gazylan XL® 6.1.2 Drugs used in Diabetes Premique Low Dose®, • Ethinylestradiol/gestodene • – Nexplanon® • Rivastigmine – patches as NICE guideline on adults with type 2 Evorel Conti® – Millinette 20/75® 7.3.5 Emergency Hormonal Alzest® diabetes • Ethinylestradiol/ Contraception NMDA- DVLA guidance on driving with • Norethisterone, desogestrel – Bimizza • Levonorgestrel – • Memantine diabetes 20/150®, Munalea Upostelle® Biguanides • Levonorgestrel - Mirena® 20/150®, Gedarel 20/150® • Ulipristal – EllaOne® • Metformin – MR as 6.4.2 Male Sex Hormones and • Ethinylestradiol / Uterine Fibroids Chapter 5 Infections Sukkarto SR®, Yaltormin Antagonists - Eloine® • Ulipristal - Esmya® Refer to separate infection quick PR®, Glucorex® Testosterone Standard strength 7.4.1 Drugs for reference guide Sulphonylureas • Sustanon 250®, Testerone • Doxazosin instant release, • Gliclazide Enate® • Tamsulosin MR Somerset CCG Quick Reference Formulary – First and Second Line Formulary Options Green is the CCG formulary preferred brand Blue is suitable for self care and available to buy OTC May 2021

7.4.2 Drugs for Urinary Frequency, Chapter 10 Musculoskeletal and Joint 12.2 Nose Mild • Azelaic – Finacea® Enuresis and Incontinence Diseases Nasal • Mildison® Lipocream • Ivermectin – Soolantra® • , NICE Guideline on Osteoarthritis • Mometasone, • hydrocortisone 1% 13.10 Anti-infective skin preparations • Tolterodine MR – Neditol NICE Guideline on Spondyloarthritis beclomethasone, Antibacterials XL®, Mariosea XL® 10.1 Rheumatic disease and gout budesonide, fluticasone Mild with antimicrobials CCG Managing Infections Guidance • Trospium MR – Regurin NSAIDs - PPI recommended furoate • Hydrocortisone/ Antifungals XL® • Ibuprofen, naproxen clotrimazole as Canesten • Clotrimazole, , • COX-2 selective NSAIDs • Ipratropium HC®, hydrocortisone/ 7.4.5 Drugs for Erectile Dysfunction • Meloxicam MRSA miconazole Daktacort® Anivirals • Sildenafil (does not need Rubefacients and topical NSAIDs • , Naseptin® Moderate • Aciclovir SLS), vardenafil, avanafil • Algesal, Transvasin, Fenbid, 12.3 Oropharynx: • 0.025% as Piroxicam, Capsaicin Ulceration and Audavate RD® or Chapter 15 Anaesthesia 7.4.6 Drugs for Premature Ejaculation Gout • , Betnovate RD®, 15.1.7 Antagonists for Central and • Dapoxetine • Acute – naproxen, hydrocortisone pellets, as Clobavate® Respiratory Depressions colchicine Bonjela® or Eumovate® Emergency treatment of poisoning Chapter 8 Malignant Disease and • Long term – allopurinol Moderate with antimicrobials Immunosuppression • Febuxostat MHRA trial Antifungal • / 8.3 Sex hormones and hormone Rheumatoid arthritis • Miconazole, Nystan® oxytetracycline/ nystatin as Appendix 2 Borderline Substances antagonists in malignant disease • Methotrexate 2.5mg Mouthwash Trimovate® Sip Feeds Comparison Chart Hormone antagonist • chlorhexidine Potent MUST Nutritional Screening • Anastrozole, letrozole Chapter 11 Eye • Betamethasone 0.1% as CMPA Guidelines for breast fed Breast cancer 11.3 Anti-infective Dry Mouth Audavate®, Betnovate® or infants • Tamoxifen, raloxifene • Antibacterial – • BioXtra®, Salivix® – Betacap® CMPA Guidelines for formula fed Prostate cancer chloramphenicol prescribe by brand 13.5.2 infants • Triptorelin – Decapeptyl • Antiviral – ganciclovir Toothpaste Vitamin D analogues SR® 11.4 Mast cell stabiliser • Self care or dentist to • Ointments, gels, lotions – • Leuprorelin – Prostap® • Sodium cromoglicate prescribe calcitriol, calcipotriol, Other Useful Information 11.6 Glaucoma tacalcitol BNF for Children Chapter 9 Nutrition and Blood • Latanoprost - PF as Chapter 13 Skin Coal Tar BNF Drug Interactions 9.1 Anaemias and blood disorders Monoprost® 13.2.1 Emollients • Psoriderm® Emulsion, coal Self care leaflet Iron deficiency • Bimatoprost – PF as • Creams – Epimax®, tar extract shampoo Self Care Quick Guide • Ferrous fumarate – liquid Eyreida® ExCetra®, Aquamax®, Combination preparations Shared Care Guides as Galfer® • Timolol – PF as Eysano® Oilatum®, Zerobase® • Capasal®, Psoriderm®, Somerset palliative care drug list and participating pharmacies Megaloblastic anaemia • Dorzolomide – PF as • Gels – Isomol Gel®, Sebco®, Cocois®, Minor Injury Units in Somerset • Folic acid, Eydelto® Myribase Gel® Diprosalic® NHS 111 service hydroxocobalamin 11.8 Dry eyes • Lotions – e45®, QV® 13.6.1 Topical preparations for NHS Think Kidneys campaign 9.2 Fluids and Electrolytes • Hypromellose • Ointments – Emulsifying • Mild – Epiduo®, Duac Once Traffic Light System • Potassium salts – Sando ointment, Epimax®, WSP, Daily® Medicines used in children, lactation K®, Kay Cee L® Chapter 12 Ear, Nose and Oropharynx Zeroderm® • Moderate – Acnecide®, and pregnancy • Electrolade® 12.1 Ear Zineryt®

9.5 Minerals Otis Externa 13.2.1.1 Bath and shower 13.6.2 Oral preparations for acne Calcium – alone self care • EarCalm®, Betnesol-N® Non-formulary based on current • Antibacterials – • Adcal® Wax removal evidence doxycycline, lymecycline Magnesium • Olive oil, docusate sodium • Hormonal – co-cyprindiol • Neomag® 13.4 Topical corticosteroids 13.6.3 Rosacea 9.6 Vitamins NICE Guideline for application of • Metronidazole – Rozex®, Vitamins should be self care corticosteroids Acea®