Somerset CCG Quick Reference Formulary – First and Second Line Formulary Options Green is the CCG formulary preferred brand Blue is suitable for self care and available to buy OTC May 2021 Chapter 1 Gastro-intestinal system NICE guideline on chronic heart failure 2.8.2 Anticoagulants • Umeclidinium – Incruse Adrenaline NICE Guideline for reflux and 2.2 Diuretic NICE guideline on DVT Ellipta® • Emerade® dyspepsia • Indapamide • Enoxaparin LAMA/LABA Combination Inhalers 3.7 Mucolytics 1.1 Dyspepsia and Reflux disease • Furosemide • Warfarin • Anoro Ellipta® or Duaklir • Carbocisteine Antacids • Spironolactone • DOACs – Dabigatran, Genuair® or Ultibro • Acetylcysteine as NACSYS® • Mucogel® • Eplerenone rivaroxaban, apixaban, Breezhale® or Spiolto Alginate 2.3 Aniti-arrhythmic edoxaban Respimat® Chapter 4 Central Nervous System • Peptac® • Amiodarone 2.9 Antiplatelets Theophylline – prescribe by brand 4.1 Hypnotic and Anxiolytics • Acidex Advance® 2.4 Betablocker • Aspirin as Danamep®, • Theophylline MR – NHS Sleep and Tiredness guide 1.2 Antispasmodic • Bisoprolol clopidogrel, dipyridamole Uniphyllin Continus®, CCG hypnotics and anxiolytics • Mebeverine tabs • Atenolol MR, prasugrel, ticagrelor Nuelin SA® Hypnotics 1.3.5 PPI • Metoprolol 2.12 Lipid Regulating Drugs • Zoplidem, zopiclone, CCG PPI deprescribing algorithm 2.5.5 ACE-inhibitors Statins 3.2 Corticosteroids (prescribe by diazepam • Lansoprazole, omeprazole, NICE guideline on hypertension • Atorvastatin, rosuvastatin, brand) NICE guideline on Anxiolytics pantoprazole, • Lisinopril Other lipid lowering corticosteroids in asthma • Diazepam esomeprazole • Ramipril caps • Ezetimibe • Beclometasone– MDI as 4.2 Antipsychotics 1.4 Acute diarrhoea ARBs Fibrates Sopradec® or Kelhale®, DPI • Risperidone, olanzapine, NICE guideline for diarrhoea in under • Losartan • Fenofibrate micronized as Easyhaler® aripiprazole, quetiapine 5s • Candesartan • Budesonide - Easyhaler® • Quetiapine XL – Sondate • Dioralyte®, Loperamide Centrally acting antihypertensive Chapter 3 Respiratory System Combination Inhalers ICS/LABA XL®, Zaluron XL® 1.5 Chronic Bowel Disorders • Methyldopa NICE guideline on COPD • Fluticasone/ salmeterol 4.2.3 Antimanic drugs NICE guideline for colitis • Moxonidine CCG respiratory home page MDI as Combisal® or • Lithium – must be Prescribe mesalazine by brand Alpha-blocker CCG Inhaler Venn Diagram AirFluSal®, DPI as prescribed by brand • Mesalazine 400mg as • Doxazosin - Doxadura® 3.1 Bronchodilators Fusacomb Easyhaler® or 4.3 Antidepressants Zintasa EC®, 500mg as 2.6 Nitrates SABA Stalpex® SSRIs and Tricyclic Pentasa SR®, sachets as • GTN spray • Salbutamol CFC MDI • Budesonide/ formoterol • Fluoxetine, sertraline, Salofalk® • Isosorbide mononitrate • DPI - Salbutamol DPI as Fobumix® citalopram 1.6 Laxatives • Isosorbide mononitrate SR Easyhaler® Triple Combination LABA/LAMA/ICS • Lofepramine, amitriptyline NICE guideline for constipation – Tardisc XL®, Monomil LABA • Vilanterol/fluticasone • Mirtazapine, venlafaxine Stimulants XL®, Chemydur XL® • Formoterol DPI – furoate/umeclidinium – • Venlafaxine MR – Vensir • Bisacodyl or senna or CCB - Dihydropyridines Easyhaler® DPI as Trelegy Ellipta® XL®, Venlalic XL®, Vencarm docusate, glycerol • Amlodipine • Formoterol MDI - Atimos® • Beclometasone/formoterol XL® suppositories • Lacidipine • Salmeterol – Soltel® or /glycopyrronium – MDI as 4.5.1 Obesity Osmotic • Lercanidipine Serevent Accuhaler® Trimbow® • Orlistat – P med can be • Macrogol - Laxido® or CCB – Rate limiting prescribe by brand • Indacaterol – Onbrez • Mometasone/indacaterol/ bought Cosmocol® • Diltiazem MR – Zemtard Breezhaler® glycopyrronium DPI as 4.7 Analgesics Bulk forming Paracetamol prescribing guidelines XL®, Slozem® • Olodaterol – Striverdi Enerzair Breezhaler® • Ispaghula husk – Fybogel • Paracetamol • Verapamil Respimat® Spacer Devices • Lactulose Weak Opioids • Verapamil MR – Half- LAMA • EasyChamber® or 1.7 Anal and rectal disorders Securon SR® or Securon AeroChamber Plus® • Codeine Haemorrhoids & Anal Fissures • Ipratropium MDI SR® 3.3.2 Leukotriene Receptor • Co-codamol 30/500 – • Anusol or Scheriproct® • Aclidinium bromide – Eklira 2.6.3 Potassium Channel Activator Antagonists Zapain® • GTN ointment -Rectogesic® Genuair® • Nicorandil • Montelukast • Tramadol – MR as Marol® • Glycopyrronium bromide - Sinus Node Regulator 3.4.1 Antihistimes bd or Tradorec XL® od Chapter 2 Cardiovascular System Seebri Breezhaler® • Ivabradine • Non sedating – loratadine, Strong Opioids NICE guideline on strokes • Tiotropium -Braltus Zonda® 2.6.4 Vasodilators cetirizine • Morphine – Zomorph®, NICE guideline on atrial fibrillation or Spiriva Respimat® • Naftidrofuryl • Sedating - chlorphenamine Morphgesic SR® Somerset CCG Quick Reference Formulary – First and Second Line Formulary Options Green is the CCG formulary preferred brand Blue is suitable for self care and available to buy OTC May 2021 • Fentanyl – Matrifen®, Chapter 6 Endocrine System Thiazolidinediones 5-ARIs • Ethinylestradiol / Fencino®, Mezolar® NHS diabetes guide • Pioglitazone • Finasteride levonorgestrel – Levest®, • Buprenorphine – Bunov®, CCG diabetes page 6.5.2 Posterior pituitary hormones Maexeni®, Rigevidon® Reletrans®, Butec® 6.1.1 Insulins and Disposables DPP-4 inhibitors and antagonists • Ethinylestradiol/ Insulin must be prescribed by brand • Alogliptin • Desmopressin - Noqdirna® norgestimate – Lizinna®, 4.7.3 Neuropathic Pain • Linagliptin, saxagliptin, Cilique® • Amitriptyline, duloxetine, Short acting sitagliptin, vildagliptin Chapter 6.6 – Drugs affecting Bone • Ethinylestradiol/gestodene gabapentin, pregabalin • Aspart – Novorapid Rapid acting insulin secretagogue Metabolism – Millinette® 30/75 4.7.4 Antimigraine • Lispro – Insulin Lispro • Repaglinide NICE advice on bisphosphonates • Ethinylestradiol/desogestr Acute Analgesia Sanofi® SGLT-2 inhibitor Patient guide to bisphosphonates el – Cimizt® 30/150, • Ibuprofen, paracetamol • Soluble – Human Actrapid, • Ertugliflozin, empagliflozin, Prevention of osteoporosis Munalea® 30/150, Anti-emetic Insuman Rapid, Humulin S dapagliflozin, canagliflozin • Alendronic acid, Gedarel® 30/150 • Domperidone - MHRA, Intermediate acting GLP-1 mimetic risedronate, ibandronate • Ethinylestradiol/drospireno metoclopramide - MHRA, • Biphasic isophane – • Lixisenatide Calcium with vitamin D – only if ne – Yacella® prochlorperazine Insuman Combe 15,25 & • Exenatide, liraglutide, bisphosphonate prescribed • Mestranol/norethisterone Triptans 50, Humulin M3 dulaglutide, semaglutide • Theical®, Accrete®, Adcal - Norinyl-1® • Sumatriptan, frovatriptan, • Biphasic insulin aspart – 6.2 Thyroid and Anti-thyroid drugs D3®, Evacal D3®, Calci-D® • Ethinylestradiol/ naratriptan, naratriptan NovoMix 30 Thyroid hormones Chapter 7 Obstetrics, Gynaecology norethisterone (tri phasic) - Prophylaxis • Biphasic Insulin lispro – • Levothyroxine and Urinary-tract Disorders Synphase® • Propranol, topiramate Humalog Mix 25 & 50 Anti-thyroid hormones 7.2 Treatment of Vaginal and Vulval • Ethinylestradiol / 4.10 Substance Dependence • Isophane insulin – Insuman • Carbimazole, Conditions levonorgestrel (tri phasic) – NHS Smokefree website Basal, Human Insulatard, propylthiouracil Atrophy TriRegol®, Logynon®, NICE guideline on stopping smoking in Humulin I 6.3 Corticosteroids • Estradiol – Ovestin®, Logynon® ED pregnancy Long acting • Prednisolone, Vagirux® 7.3.2Progesteron only contraceptives • NRT – patches, gum, • Insulin glargine – hydrocortisone Fungal infections (POP) lozenge, spray Semglee®, Abasaglar, 6.4.1 Hormone Replacement Therapy • Fluconazole, clotrimazole • Desogestrel • Bupropion, varenicline Lantus Prescribe by brand 7.3 Contraceptives • Norethisterone – Noriday® Opioid Dependence • Insulin detemir – Levemir Unopposed oestrogen Methods of contraception • Levonorgestrel – • Methadone – Physeptone® • Insulin degludec – Tresiba • Elleste Solo®, Bedol®, Contraceptive pill suitable for patients Norgeston® • Buprenorphine sublingual Pen Needles and Lancets Evorel® taking hepatic enzyme-inducing drugs 7.3.2.3 Intra uterine POP tabs Compatibility chart Cyclical combined guideline • Mirena®, Jaydess®, 4.11 Drugs for Dementia • Microdot Max®, GlucoRx • Elleste Duet®, Clinorette®, FSRH guide to Drug Interactions with Levosert® Initiated by specialist only Carepoint®, GlucoRx Cyclo-progynova®, Evorel Hormonal Contraception Long acting reversible contraception AChE Inhibitors Carepoint Ultra® Sequi® 7.3.1 Combined hormonal • Medroxy-progesterone – • Donepezil • Microdot Plus®, Fastclix®, Continuous combined contraceptives Depo-Provera®, Sayana • Galantamine – MR as GlucoRx® • Kliofem®, Kliovance®, Low strength Press® Gatalin XL® or Gazylan XL® 6.1.2 Drugs used in Diabetes Premique Low Dose®, • Ethinylestradiol/gestodene • Etonogestrel – Nexplanon® • Rivastigmine – patches as NICE guideline on adults with type 2 Evorel Conti® – Millinette 20/75® 7.3.5 Emergency Hormonal Alzest® diabetes Progestogens • Ethinylestradiol/ Contraception NMDA-receptor Antagonist DVLA guidance on driving with • Norethisterone, desogestrel – Bimizza • Levonorgestrel – • Memantine diabetes medroxyprogesterone 20/150®, Munalea Upostelle® Biguanides • Levonorgestrel - Mirena® 20/150®, Gedarel 20/150® • Ulipristal – EllaOne® • Metformin – MR as 6.4.2 Male Sex Hormones and • Ethinylestradiol / Uterine Fibroids Chapter 5 Infections Sukkarto SR®, Yaltormin Antagonists drospirenone - Eloine® • Ulipristal - Esmya® Refer to separate infection quick PR®, Glucorex® Testosterone Standard strength 7.4.1 Drugs