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Localized Whirlpool Folliculitis in a Football Player Justin J Localized Whirlpool Folliculitis in a Football Player Justin J. Green, MD, Camden, New Jersey Pseudomonas aeruginosa folliculitis occurs in pa- lege football player, sustained a left ankle inversion tients exposed to contaminated water. Most out- sprain 2 days previously. Examination revealed mul- breaks are associated with whirlpools. The infec- tiple, 2- to 6-mm erythematous papules and pustules. tion is characterized by follicular, erythematous The pustules had a distinct light green hue with a cir- papules and pustules located on immersed body cumferential border of intense erythema (Figure 1). surfaces. Most reported cases are the result of Many of the papules and pustules were folliculo- recreational water use, occur in a diffuse pattern, centric. The eruption was clustered in two areas, and are devoid of green pustular pigment changes. separated by a few centimeters, on the medial aspect The case described occurred in a football player of the left leg. The area was tender, but without after whirlpool treatment for an ankle strain. Green edema, and the base of surrounding skin was non- pustules and a localized affected area are unusual erythematous. There was no associated lym- aspects of this case. phadenopathy. Further questioning revealed that the patient received a 20-minute hot whirlpool seudomonas aeruginosa is an aerobic, motile, treatment exclusively to the left leg (distal to the gram-negative rod that inhabits areas of mois- knee), approximately 24 hours prior to the eruption. P ture. The organism can live in sinks, jet fuel, Treatment with 250 mg ciprofloxacin orally twice antiseptic solutions, soil, sewage, flowers, vegetables, daily for 7 days was initiated, but follow-up revealed insects, and warm- and cold-blooded animals.1,2 It can that the patient took just one dose. The lesions re- be present in the normal flora of the external ear, ax- solved without sequela 5 days later. illae, anogenital region, and intestines. The cuta- neous manifestations of P. aeruginosa are as varied as Discussion its habitat and include otitis externa, malignant oti- The first outbreak of whirlpool folliculitis was de- tis externa, green nail syndrome, toe web infections, scribed by McCausland and Cox4 in 1975. Since superinfections in antibiotic-treated acne vulgaris, su- then, there have been numerous reports of this en- perinfections in traumatized skin (burns, decubitus ul- tity associated with whirlpools and hot tubs, with cers), “whirlpool” or “hot-tub” folliculitis, blastomy- fewer reports associated with waterslides, physiother- cosis-like pyoderma, ecthyma gangrenosum, and apy pools, swimming pools, and saunas. More recent necrotizing fasciitis.3 variants of this entity include diving suit dermatitis5 and folliculitis attributed to use of synthetic bathing Case Report sponges,6,7 loofah sponges,8 and wax depilation.9 A 20-year-old college student with no significant The predilection of P. aeruginosa for these locales past medical history presented with an acute erup- and its users are based upon many factors. It is known tion on his left leg. The patient stated that the area that P. aeruginosa infects superhydrated stratum was “sensitive to touch” prior to noticing the erup- corneum.10 In addition, the organism can withstand tion. He denied fevers, chills, arthralagias, dysuria, temperatures up to 41.4°C,11 and these high temper- cough, malaise, headache, sore throat, rhinorrhea, atures may, in turn, dilate follicular openings and af- otalgia, and ocular complaints. The patient, a col- ford easier accessibility.12 The turbulence in whirlpools creates skin desquamation and provides or- Dr. Green is a Dermatology Resident, Division of Dermatology, ganic carbon debris for bacterial overgrowth. High Department of Medicine, University of Medicine and Dentistry of temperatures and ammonia excreted by bathers de- New Jersey-Robert Wood Johnson Medical School at Camden, Cooper Hospital, Camden, New Jersey. crease the effectiveness of chlorine. Chloramines, the REPRINT REQUESTS to 19 Charles Lane, Cherry Hill, New Jersey product of chlorine and ammonia, are inferior an- 08003. tibacterials.1 Bathing suit or diving suit occlusion can VOLUME 65, JUNE 2000 359 LOCALIZED WHIRLPOOL FOLLICULITIS FIGURE 1. Follicular, erythema- tous papules and green pus- tules on the leg. facilitate P. aeruginosa infection,5,10,13 although several ear symptoms in 70%, of 117 persons affected by case reports reveal no garments being worn during ex- “Pseudomonas dermatitis” associated with a swimming posure. Trauma promotes further bacterial penetra- pool. These symptoms do not imply systemic inva- tion as evidenced by reports of infection after shav- sion. Rarely, pneumonia, otitis media, and urinary ing and intense sponge use.6,8 Most outbreaks are tract infections have been related to Pseudomonas in associated with closed-cycle water units, which cir- whirlpools.20-22 culate a fixed amount of water. The eruption typically resolves in 7 to 14 P. aeruginosa involved in the first outbreak of days1,3,18,19 with occasional postinflammatory hyper- whirlpool follicultis were serotypes O:4 and O:11.4 pigmentation. Recurrent folliculitis after recurrent Serotype O:11 represents the most commonly iden- exposure has been documented,19 as well as a recur- tified group in Pseudomonas folliculitis. Other less rence seen 3 months after initial exposure.2 In one commonly identified serotypes are O:9, O:4, and O:1. outbreak, 23% of affected persons had a recurrence “Non-O:11” serotypes have been associated with after initial clearance, with one-half of these indi- “non-whirlpool” P. aeruginosa folliculitis. Specifically, viduals receiving topical antibiotics.14 O:3 and O:16 have been isolated in synthetic The clinical differential diagnosis of this eruption sponges,6 while O:10 was found in a loofah sponge.8 may include Staphylococcus aureus folliculitis, Majoc- The incubation period of P. aeruginosa folliculitis chi’s granuloma, eosinophilic pustular folliculitis, mil- is usually between 8 and 48 hours. Previous reviews iaria, secondary syphilis, insect bites, papular ur- describe the lesions as erythematous papular and pus- ticaria, scabies, and acne vulgaris. tular eruptions, many with follicular pustules,14-17 and Histopathologic examination displays an acute less commonly with macules, vesicles, and nodules. suppurative folliculitis: mild acanthosis and spongio- Frequently the areas are pruritic,2,3,6,18 and urticarial sis of the epidermis, a distended and disrupted in- and papulourticarial lesions have been described.2,16,19 fundibulum with dense neutrophilic infiltrate and The eruption is limited to exposed areas, with the hair fragments found within the canal, neutrophils face and neck commonly spared in whirlpool-associ- within the outer root sheath, and dense superficial ated cases (the areas usually not immersed). The and deep perivascular inflammatory cell infiltrate eruption may be distributed more predominantly un- consisting of mononuclear cells and neu- der the bathing suit. trophils.2,15,18,19,23 Small, deep dermal abscesses have Associated symptoms include painful eyes, ear- been identified.15,19 Gram’s stain may reveal slender, ache, sore throat, headache, fever, painful swollen pink rods, and cultures of skin and suspected water breasts (in males and females), malaise, rhinorrhea, can confirm the diagnosis. nausea, vomiting, and abdominal cramps.1,14-16,18 The case presented is unique in several aspects. Thomas et al14 reported ocular symptoms in 75%, and First, the eruption was seen in a remarkably localized 360 CUTIS® LOCALIZED WHIRLPOOL FOLLICULITIS area. The green hue visualized in many of this pa- in widespread eruptions, recurrences,5 or in those pa- tient’s pustules is a characteristic of P. aeruginosa, and tients with associated systemic findings. In im- is well-described in green nail syndrome, toe web in- munocompromised patients, systemic therapy with fections, and superinfections of burns and ulcers. P. aminoglycosides or anti-Pseudomonas cephalosporins aeruginosa folliculitis, however, is not generally re- (ceftazidime or cefepime) may be warranted, since garded to display such characteristic pigment changes spread from folliculitis to ecthyma gangrenosum has as was seen in this case. been documented.26 The exposure time of 20 minutes and the small amount of body surface area treated seemed unlikely REFERENCES factors to yield an infection. However, it should be 1. Berger RS, Seifert MR: Whirlpool folliculitis: a review of noted that the football player’s legs had noticeable its cause, treatment, and prevention. Cutis 45: 97-98, 1990. abrasions and scratches that may have contributed 2. Sausker WF, Aeling JL, Fitzpatrick JE, Judson FN: to entry into follicular orifices. This may explain the Pseudomonas folliculitis acquired from a health spa two discrete areas of clustering on the left leg. It is whirlpool. JAMA 239: 2362-2365, 1978. known that P. aeruginosa has a predilection for dam- 3. Greene SL, Su WP, Muller SA: Pseudomonas aeruginosa in- aged epithelium,6,8,9,17 and an analogous situation oc- fections of the skin. Am Fam Physician 29: 193-200, 1984. curs with ocular Pseudomonas infections after abra- 4. McCausland WJ, Cox PJ: Pseudomonas infection traced to sions to the cornea by contact lenses.24 Additionally, a motel whirlpool. J Environ Health 37: 455-459, 1975. therapeutic whirlpools are smaller than those used 5. LaCour JP, Baze PE, Castanet J, Dubois D, Poundenx M, for recreational purposes, and therefore have less
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