JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2018 NO.4）
Vas-CogVas-Cog JournalJournal
No.4 Apr 001.1. 2018
Official Journal of Vas-Cog Japan Society
1 ISSN : 24239372 JAPANESE SOCIETY OF VASCULAR COGNITIVE IMPAIRMENT（2018 NO.4）
Greetings from Vas-Cog Japan, the Japanese Society for Vascular Cognitive Impairment
Ryuichi Morishita, MD, PhD President: The Japanese Society for Vascular Cognitive Impairment
I am Dr. Ryuichi Morishita from Osaka University, program at a great venue organized by the chairmen. and I took over as President of the Japanese Society The 9th annual meeting is to be held at Beppu for Vascular Cognitive Impairment from Dr. Koji Abe. International Convention Center August 4-5, 2018, I would like to further develop this society - which with Dr. Katsuya Urakami and Dr. Etsuro Matsubara was first developed by Dr. Nagata, the first President, as chairmen, so we are expecting many of you to and Dr. Abe, the second President - to the best of my attend. ability, with the cooperation of all the members in Our affiliate Vas-Cog Asia has been revitalizing our society, so your kind support would be greatly year by year. The 6th meeting held in Nanjing City appreciated. on October 26, 2017, was a huge success with Vas- Vas-Cog Japan, which is in its eighth year from its Cog Asia Director, Dr. Koji Abe and Dr. Shinichiro time as a study group, has developed quite Uchiyama serving as lecturers and moderators. The considerably. As our society has already met the 7th annual meeting will be held in Jakarta on requirements to be registered as an academic September 6, 2018. Vas-Cog World will also be held organization in the Science Council of Japan with in Hong Kong November 24-27, 2018. regard to the number of members, membership With regard to the major dementias such as Lewy management and publication of journals, the body dementia, Parkinsonʼs Disease-related dementia Chairman for the Promotion of Becoming a Society, and frontotemporal dementia, as well as the rapidly Dr. Katsuya Urakami, has been working on our increasing Alzheimerʼs Disease (AD) and vascular application for the registration. dementia, Vas-Cog Japan has been established to Also, our newsletter, which was first published in elucidate the relationship between blood vessels and 2016 in Japanese and English, has been distributed dementia that are attracting attention in our rapidly to related academic societies in various countries aging society with the aim of advancing clinical and and is well received thanks to the hard work by fundamental research from a new broader viewpoint former President Dr. Abe. Fortunately, thanks to the beyond the concept that it is merely a vascular efforts of the Chief Editor of the academic magazine, dementia as classified conventionally. Dr. Mikio Shoji, it has developed into Vas-Cog As the government has set the era of a lifetime at Journal, a joint publication with Vas-Cog Asia. one hundred years, prevention and treatment of In addition, the number of members also increased dementia is becoming a top priority task, such as the steadily due to the efforts of the Chairman for development of health care strategy for a one-year Increasing Membership and Public Relations, Dr. extension of life expectancy by 2020. In addition, Haruo Hanyu. As of August 2017, we have 143 Japan is bidding to host the World Exposition in active members, including 26 directors and 54 Osaka in 2025 councilors and the membership is expected to In response to such new academic and social increase in the future. Furthermore, the financial demands, our society will continue to elucidate the structure has been going very well. I sincerely thank deep linkage between functional and organic the members, councilors, and directors who have obstacles in blood vessels and the onset of dementia, supported this society for all these achievements. and will develop new diagnostic and therapeutic I would like to continue to strengthen the financial methods. By doing so, we aim to contribute to the structure under the guidance of Dr. Yoshio Ikeda, maintenance and development of a healthily aging who is the newly appointed Chairman of Financial society of all human beings, including Japanese. Affairs. Regarding conflicts of interest, we plan to set Our society has developed steadily under the up a COI committee and prepare provisions under leadership of former Presidents Dr. Nagata and Dr. the direction of the Chairman, Dr. Masahiko Suzuki. Abe. It is a unique academic society that covers a The 8th Annual Meeting of Vas-Cog Japan was wide variety of interdisciplinary fields such as held with great success on August 5, 2017, at cardiology, neurology, and brain surgery through the Toranomon Hills, with Dr. Shinichiro Uchiyama and active participation of everyone, so we are looking Dr. Issei Komuro as chairmen. I believe that many forward to the participation of many of you. participants were satisfied with the very attractive April 1, 2018
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Reports of the Vas-Cog Japan 2017
Shinichiro Uchiyama, MD, PhD International University of Health and Walfare / Sanno Hospital and Sanno Medical Center
The 8th annual meeting of Vas-Cog Japan was CARASIL, molecular pathophysiology, and held on August 5, 2017 in Toranomon Hills Forum, development of new treatments, and there were Tokyo. Stroke and dementia are the first and high levels of enthusiastic discussions. We invited second leading causes of dependency, which Prof. Vladimir Hachinski as a guest speaker for the should be overcome with the top priority in order Special Lecture from Canada. He gave a very to prolong health life. Stroke and dementia share fascinating talk on cerebral white matter disease, the same risk factors, and thereby they can be and deep impression to audiences fulfilled in the prevented simultaneously by controlling these room (Figure 1). There were lectures on imaging vascular risk factors. Based on these viewpoints, tests and cognitive tests in the Teaching Course, the topic of this annual meeting was determined to which were very useful for clinical practice. A be “Cognitive Impairment Thought from Organ variety of oral abstracts from bench to bedside Linkage”. Reflecting increased and expanded were presented and much discussed. I was concern to dementia, not only specialists of impressed with many participants before the Japanese Society of Neurology and Japan Stroke presentations of poster abstracts and enthusiastic Society but also many non-specialists and general discussion. Presenters awarded YIA were all physicians attended, and the total number of excellent and talented, who were hopes for future participants was recorded to be the largest in of our society (Figure 2). I would be very happy if annual meetings. In Symposium 1 entitled “Heart our message that dementia is preventable along Diseases and Dementia”, many latest knowledges with stroke by managements of vascular risk were presented, which was reputed timely to meet factors was useful for participants’ clinical practice the topic of this meeting. In Symposium 2 entitled in patients with stroke and/or dementia as well as “Cerebral Small Vessel Disease”, frontline those with huge number of pre-stroke and/or pre- researches and latest reviews were presented dementia. regarding amyloid angiopathy, CADASIL and
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Vas-Cog Japan 2017
Issei Komuro, MD, PhD Department of Cardiovascular Medicine, The University of Tokyo Graduate School of Medicine
On August 5th, we had Vas-Cog Japan 2017 at decreased whereas aortic stenosis and mitral valve Toranomon Hills. There were total 206 regurgitation have been increased. Valvular participants, which is the largest number of Vas- diseases also finally resulted in heart failure and a Cog Japan. There were one special lecture, two decrease of blood flow in the brain induces symposia (1. Cardiac diseases and dementia, 2 dementia. The number of patients of atrial Cutting-edge research of brain microvascular fibrillation has also been increased and diseases and dementia), YIA, three oral cardiogenic cerebral infarction has been increased, presentations, two educational seminars, four leading to dementia. Therefore, there is intimate cosponsored seminars and five posters. Prof. relationship among cardiovascular diseases, stroke Vladimir Hachinski (The University of Western and dementia, and it is becoming more and more Ontario) gave us a wonderful special lecture important to promote prevention and treatment for entitled “Cognition, White Matter and Red Flags” cardiovascular diseases and stroke to prevent and greatly attracted all audience. This was the dementia together with many related societies. The first time for me to attend the Vas-Cog Japan and I Japanese Circulation Society has made five-year have learned many things. In particular, I chaired strategy for stroke and cardiovascular diseases symposium 1 and have recognized again that there with many related societies at last year. In this is intimate relation between cardiac diseases and sense too, Vas-Cog Japan2017 was very important dementia. There has been a big change in cardiac and had a big meaning for me. I would like to diseases in Japan by becoming super aging express sincere thanks to president Uchiyama, vice societies. Twenty years ago, number one cause of president Kitagawa, and all people who helped us cardiovascular death was myocardial infarction, to hold Vas-Cog Japan2017 as well as to all but now treatment for myocardial infarction has participants. improved and death rate has been decreased. Instead, mobility and mortality of heart failure have been increased. Valvular diseases are also changed. Rheumatic valvular diseases have been
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Meeting report of Vas-Cog Asia 6 from Nanjing
Koji Abe, MD, PhD Vas-Cog Asia President
I would like to celebrate the great success of many active members, which is dedicated to Vas-Cog Asia 6, which was held in Nanjing on elucidate the mechanism of vascular factors in October 26 afternoon (2017) always jointing with Alzheimer’s disease and related dementia, and to Asia-Pacific Stroke Conference (APSC) based on the contribute potential therapy for dementia people great supports by Professor Ying-Dong Zhang in Asia. Many vascular risk factors (VRFs) are (APSC2017 chair) and Professor Jie Yang related to cognitive decline and affective- (Nanjing). We had 27 participants from Japan, emotional changes in dementia patients especially Taiwan, Korea, China, Hong Kong, Malaysia, in elder or eldering countries in Asia. Next Vas-Cog Indonesia and India. There were variety of Asia is going to be held in Jakarta (Indonesia) on important presentations in the present conference. September 6, 2018 as Vas-Cog Asia 7, and Vas-Cog Many basic science, translational research, clinical World is going to be held in Hong Kong on trials and evidence were discussed especially on November 14-17 organized by our director the aspects of Alzheimer’s disease (AD), vascular Vincent Mok. All of you are welcome to actively dementia (VD), behavioral and psychiatric join these forthcoming Vas-Cog meetings to symptoms of dementia (BPSD), and their important present and discuss on vascular factors of all type vascular involvement. In the Young Flash Talks dementia. session, young Asian researchers from Japan, October 26, 2017 Taiwan, and Hong Kong presented pretty nice talks, which were successfully congratulated. Vas-Cog Asia society is an independent society with 24 directors from most Asian countries and
Malaysia China Japan Taiwan Indonesia Malaysia (Tan) (Chui) Japan (Tiang) China (Ong) (Poi) (Chi) (Omote) (Wang)
Hong Kong China Japan Taiwan Taiwan (Lam) (Yang) Japan Hong Kong India (Uchiyama) (Abe) (Mok) (Lee) (Hu) China India (Sylajofm) (Zhang) Philippines (Mehndiratta) (Marasigan) Indonesia (Asnelia)
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Welcome to Vas-Cog Japan 2018
Section of Environment and Health Science, Oita University Faculty of Medicine Department of Biological Regulation, Department of Neurology Faculty of Medicine, Tottori University Etsuro Matsubara Katsuya Urakami
We are pleased to welcome you to the Vas-Cog fight against dementia. In the Vas-Cog Japan Japan 2018 to be held at the Beppu International 2018, we have decided “Elucidation of the Convention Center (B-con Plaza), August 4-5, significance of vascular lesions in dementia-aiming 2018. to nurture young physicians and researchers-” as a theme. Japan faces a super-aging society in which the number of patients suffering from dementia has Vas-Cog Japan 2018 will be the first time that soared. Nobody doubt that this is the urgent we have a two-day meeting, which allows you to problem that should be settled from a socio- participate and visit for a great deal of information economic standpoint. Recently, it becomes clear regarding vascular cognitive impairments. As you that life-style related disease as well as the know, Beppu is a hot spring town representing vascular lesions occurring afterwards are heavily “Onsen-ken Oita”. After a moderate stimulation to involved in the onset and exacerbation of dementia the brain at the meeting, we are sure that you will such as Alzheimerʼs disease. We would like to be able to refresh both mind and body with the focus on the relationship between the vascular delicious sake and seasonal food as well as a hot pathophysiology and the onset of dementia. Our spring. We are looking forward to seeing you in society also needs to nurture and recruit young Beppu. physicians and researchers having great energy to
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Reports of Vas-Cog Japan Council Meeting
Ryuichi Morishita, MD, PhD Osaka University
The 9th board member meeting and council meeting ・ Approximately ten members from the committee will for Japan Vas-Cog were held together on the 5th of be selected for peer-review committee members and August, 2017 in Toranomon Hills Forum 4th floor, with editorial committee members 19 board members, 2 auditors and 11 councilors in *The COI Chairperson, Director Suzuki attendance. About COI of academic journals and academic congress The President and members reported on and Advance creation of provisions concerning presenters approved the topics below: and authors at the same time as posting regulations [Membership] 155 regular members (20th July 2017) ※ Refer to the same academic conference as above. [Constitutional revision] The fiscal year and personnel *The chairperson of financial affairs, Dr. Ryuichi will be from April to March, and personnel changes Morishita, reported: decided at the general meeting in August will take Both auditors, Dr. Shimamura and Dr. Matsumura effect from April of the following year. reported that accounting was properly conducted in the audit report. [Report from each chairman] *The chairperson for the promotion of becoming a [Plans for future meetings] society, Dr. Katsuya Urakami, discussed the 1. The 11th ICVD (22nd and 23rd of February 2018 / application for registration of academic groups. One will be held in Paris) hundred members have been cleared, which is one of 2. The 9th Meeting (4th Sat. and 5th Sun. of August, 2018) the certification requirements. However, as the B-ConPlaza, Beppu International Convention Center following conditions have not been satisfied, it will be in Oita necessary to wait for certification for several years. Organizers: Dr. Katsuya Urakami and Dr. Etsuro
[Name list]
● Executive Advisor Hiroshi Mori (Osaka City University/ Tamiya Hospital)
● President ● Executive Directors (General Affairs) Ryuichi Morishita (Osaka University) Yoshio Ikeda (Gunma University)
● Executive Directors Masahiro Akishita (The University of Tokyo) Koji Abe (Okayama University) Shinichiro Uchiyama Katuya Urakami (Tottori University) (International University of Health and Welfare) Nobuya Kawabata (Yachiyo Hospital) Kazuo Kitagawa (Tokyo Womenʼs Medical University) Koichi Kozaki (Kyorin University) Issei Komuro (The University of Tokyo) Masataka Sata (Tokushima University) Mikio Shoji (Hirosaki University) Masahiko Suzuki Syunya Takizawa (Tokai University) (The Jikei University School of Medicine) Yasuo Terayama (Iwate Medical University) Hidekazu Tomimoto (Mie University) Ken Nagata Haruo Hanyu (Tokyo Medical University) (Research Institute for Brain and Blood Vessels) Toshiya Fukui (Kawasaki Memorial Hospital) Masatsugu Horiuchi (Ehime University) Etsuro Matsubara (Oita University) Toshiki Mizuno (Kyoto Prefectural University of Medicine) Shokei Mitsuyama (Kumamoto University) Masaru Mimura (Keio University) Shuhei Yamaguchi (Shimane University) Masahito Yamada (Kanazawa University)
● Auditors Munehisa Shimamura (Osaka University) Miyuki Matsumura (Institute of Geriatrics Tokyo Womenʼs Medical University)
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● Councilors Hitoshi Aizawa (Tokyo Medical University) Yasuhiro Aso (Oita University Hospital) Satoshi Abe (Shimane University Hospital) Masaki Ikeda (Gunma University Hospital) Nobuyoshi Ishii (Oita University) Hiroo Ichikawa (Showa University Fujigaoka Hospital) Masafumi Ihara Jun Iwanami (Ehime University) (National Cerebral and Cardiovascular Center) Yumiko Uchiyama Takahiko Umahara (Tokyo Medical University) ※ (Tokyo Womenʼs Medical University) Takao Urabe (Juntendo University Urayasu Hospital) Yasuyuki Ohta (Okayama University) Sumito Ogawa (The University of Tokyo) Hiroaki Oguro (Shimane University Hospital) Kenjiro Ono (Showa University) Haruhisa Kato (Tokyo Medical University) Tatsushi Kamiya (Kamiya Clinic) Yumi Kameyama (The University of Tokyo Hospital) Noriyuki Kimura (Oita University) Hitomi Kurinami (Osaka University) Minoru Kouzuki (Tottori University) Taro Kojima (The University of Tokyo) Hisatomo Kowa (Kobe University) Masaki Kondo (Kyoto Prefectural University of Medicine) Kenji Sakai (Kanazawa University Hospital) Hirofumi Sakurai (Tokyo Medical University) Naoyuki Sato Masayuki Satoh (Mie University) (Center for Development of Advanced Medicine for Dementia) Yoshiki Takao (Kurashiki Heisei Hospital) Daiki Takano (Yokohama General Hospital) Ayumi Takamura (Tottori University) Shuko Takeda (Osaka University) ※ Yasushi Takeya (Osaka University) Kentarou Deguchi (Okayama University) Hiroo Terashi (Tokyo Medical University) Takashi Tokashiki (Okinawa National Hospital) Takahiko Tokuda Kazuaki Nagashima (Gunma University) (Kyoto Prefectural University of Medicine) Masao Nagayama (IUHW Atami Hospital) Yu Hasegawa (Kumamoto University) Yasuto Higashi (Himeji Central Hospital) Yukihito Higashi ※ (Research Institute for Radiation Biology and Medicine) Nozomi Hishikawa (Okayama University) Yukio Fujita (Gunma University) Kouki Makioka (Gunma University Hospital) Yasuhiro Manabe (National Hospital Organization Okayama Medical Center) Toru Minamino (Niigata University) ※ Takafumi Miyachi (Yanai Medical Center) ※ Min Rijuan (Ehime University) Kazuhiro Muramatsu (Tokyo Dental College Ichikawa General Hospital) Kenichi Meguro (Tohoku University) Masaki Mogi (Ehime University) Hideki Mochizuki (Osaka University) Takashi Yamazaki (Research Institute for Brain and Blood Vessels-Akita) Toru Yamashita (Okayama University Hospital) Hiroshi Yoshizawa (Tokyo Womenʼs Medical University) Kouji Wakayama (The University of Tokyo) Yosuke Wakutani (Kurashiki Heisei Hospital)
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Editor’s Note
Mikio Shoji MD, PhD Hirosaki University
The 1st meeting of Japanese research group of direction of research for vascular cognitive vascular dementia had started in 2010. Since then, impairment. Respective symposiums, lectures, 38 we held 8th annual meeting as Vas-Cog Japan 2017 in poster presentations and lively discussion were all Tokyo. Japanese Society of Vascular Cognitive higher level and impressive than those of previous Impairment Vas-Cog japan are now developing with meetings. More than 206 doctors and researches more than 150 association members. The 4th issue of including many young investigators joined the Vas-Cog Journal reports the outline of the 8th annual meeting at Toranomon Hils. I deeply realized the meeting, VAS-COG Japan 2017, hosted by Professor developing of our society. Vas-Cog Japan 2018 will Shinichirou Uchiyama and Professor Issei Komuro at be convened at Beppu, Ooita prefecture. We are Toranomon Hils in August 5, 2017. Invitation lecture looking forward to manuscript publication in the next delivered by Professor Vladimir Hatchinski from issue, Vol 5. I hope Japanese society and Journal University of Western Ontario, a famous authority in could contribute further in this world-wide field. this field, was deeply impressive and suggested future
The past and future annual meeting of Vas-Cog Japan
The 1 st Meeting : August, 2010 (Tokyo) Chairman : Ken Nagata and Toshiya Fukui The 2nd Meeting : August, 2011 (Tokyo) Chairman : Koji Abe and Shokei Mitsuyama The 3rd Meeting : August, 2012 (Tokyo) Chairman : Ryuichi Morishita, Yasuo Terayama, and Koji Abe The 4th Meeting : August, 2013 (Tokyo) Chairman : Mikio Shoji and Haruo Hanyu The 5th Meeting : August, 2014 (Kyoto) Chairman : Toshiki Mizuno and Hidekazu Tomimoto The 6th Meeting : August, 2015 (Tokyo) Chairman : Shinya Kawabata and Shuhei Yamaguchi The 7th Meeting : August, 2016 (Kanazawa) Chairman : Masatsugu Horiuchi and Masahito Yamada The 8th Meeting : August, 2017 (Tokyo) Chairman :Shinichiro Uchiyama and Issei Komuro The 9th Meeting : August, 2018 (Beppu) Chairman : Katsuya Urakami and Etsuro Matsubara The 10th Meeting : August, 2019 (Tokyo) Chairman : Masahiro Akishita and Yoshio Ikeda The 11th Meeting : September, 2020 (Tokushima) Chairman : Shunya Takizawa and Masataka Sata The 12th Meeting : August, 2021 (planned) Chairman : Kazuo Kitagawa and Koichi Kozaki The 13th Meeting : August, 2022 (planned) Chairman : Masahiko Suzuki - to be continued -
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