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JAPANESESOCIETYOFVASCULARCOGNITIVEIMPAIRMENT(2018NO.4) Vas-CogVas-Cog JournalJournal No.4 Apr 001.1. 2018 Official Journal of Vas-Cog Japan Society 1 ISSN:24239372 JAPANESESOCIETYOFVASCULARCOGNITIVEIMPAIRMENT(2018NO.4) Greetings from Vas-Cog Japan, the Japanese Society for Vascular Cognitive Impairment Ryuichi Morishita, MD, PhD President:TheJapaneseSocietyforVascularCognitiveImpairment IamDr.RyuichiMorishitafromOsakaUniversity, programatagreatvenueorganizedbythechairmen. andItookoverasPresidentoftheJapaneseSociety The9thannualmeetingistobeheldatBeppu forVascularCognitiveImpairmentfromDr.KojiAbe. InternationalConventionCenterAugust4-5,2018, Iwouldliketofurtherdevelopthissociety-which withDr.KatsuyaUrakamiandDr.EtsuroMatsubara wasfirstdevelopedbyDr.Nagata,thefirstPresident, aschairmen,soweareexpectingmanyofyouto andDr.Abe,thesecondPresident-tothebestofmy attend. ability,withthecooperationofallthemembersin OuraffiliateVas-CogAsiahasbeenrevitalizing oursociety,soyourkindsupportwouldbegreatly yearbyyear.The6thmeetingheldinNanjingCity appreciated. onOctober26,2017,wasahugesuccesswithVas- Vas-CogJapan,whichisinitseighthyearfromits CogAsiaDirector,Dr.KojiAbeandDr.Shinichiro timeasastudygroup,hasdevelopedquite Uchiyamaservingaslecturersandmoderators. The considerably. Asoursocietyhasalreadymetthe 7thannualmeetingwillbeheldinJakartaon requirementstoberegisteredasanacademic September6,2018.Vas-CogWorldwillalsobeheld organizationintheScienceCouncilofJapanwith inHongKongNovember24-27,2018. regardtothenumberofmembers,membership WithregardtothemajordementiassuchasLewy managementandpublicationofjournals,the bodydementia,ParkinsonʼsDisease-relateddementia ChairmanforthePromotionofBecomingaSociety, andfrontotemporaldementia,aswellastherapidly Dr.KatsuyaUrakami,hasbeenworkingonour increasingAlzheimerʼsDisease(AD)andvascular applicationfortheregistration. dementia,Vas-CogJapanhasbeenestablishedto Also,ournewsletter,whichwasfirstpublishedin elucidatetherelationshipbetweenbloodvesselsand 2016inJapaneseandEnglish,hasbeendistributed dementiathatareattractingattentioninourrapidly torelatedacademicsocietiesinvariouscountries agingsocietywiththeaimofadvancingclinicaland andiswellreceivedthankstothehardworkby fundamentalresearchfromanewbroaderviewpoint formerPresidentDr.Abe.Fortunately,thankstothe beyondtheconceptthatitismerelyavascular effortsoftheChiefEditoroftheacademicmagazine, dementiaasclassifiedconventionally. Dr.MikioShoji,ithasdevelopedintoVas-Cog Asthegovernmenthassettheeraofalifetimeat Journal,ajointpublicationwithVas-CogAsia. onehundredyears,preventionandtreatmentof Inaddition,thenumberofmembersalsoincreased dementiaisbecomingatopprioritytask,suchasthe steadilyduetotheeffortsoftheChairmanfor developmentofhealthcarestrategyforaone-year IncreasingMembershipandPublicRelations,Dr. extensionoflifeexpectancyby2020. Inaddition, HaruoHanyu. AsofAugust2017,wehave143 JapanisbiddingtohosttheWorldExpositionin activemembers,including26directorsand54 Osakain2025 councilorsandthemembershipisexpectedto Inresponsetosuchnewacademicandsocial increaseinthefuture. Furthermore,thefinancial demands,oursocietywillcontinuetoelucidatethe structurehasbeengoingverywell. Isincerelythank deeplinkagebetweenfunctionalandorganic themembers,councilors,anddirectorswhohave obstaclesinbloodvesselsandtheonsetofdementia, supportedthissocietyforalltheseachievements. andwilldevelopnewdiagnosticandtherapeutic Iwouldliketocontinuetostrengthenthefinancial methods.Bydoingso,weaimtocontributetothe structureundertheguidanceofDr.YoshioIkeda, maintenanceanddevelopmentofahealthilyaging whoisthenewlyappointedChairmanofFinancial societyofallhumanbeings,includingJapanese. Affairs.Regardingconflictsofinterest,weplantoset Oursocietyhasdevelopedsteadilyunderthe upaCOIcommitteeandprepareprovisionsunder leadershipofformerPresidentsDr.NagataandDr. thedirectionoftheChairman,Dr.MasahikoSuzuki. Abe. Itisauniqueacademicsocietythatcoversa The8thAnnualMeetingofVas-CogJapanwas widevarietyofinterdisciplinaryfieldssuchas heldwithgreatsuccessonAugust5,2017,at cardiology,neurology,andbrainsurgerythroughthe ToranomonHills,withDr.ShinichiroUchiyamaand activeparticipationofeveryone,sowearelooking Dr.IsseiKomuroaschairmen.Ibelievethatmany forwardtotheparticipationofmanyofyou. participantsweresatisfiedwiththeveryattractive April1,2018 2 JAPANESESOCIETYOFVASCULARCOGNITIVEIMPAIRMENT(2018NO.4) Reports of the Vas-Cog Japan 2017 Shinichiro Uchiyama, MD, PhD InternationalUniversityofHealthandWalfare/ SannoHospitalandSannoMedicalCenter The8thannualmeetingofVas-CogJapanwas CARASIL,molecularpathophysiology,and heldonAugust5,2017inToranomonHillsForum, developmentofnewtreatments,andtherewere Tokyo.Strokeanddementiaarethefirstand highlevelsofenthusiasticdiscussions.Weinvited secondleadingcausesofdependency,which Prof.VladimirHachinskiasaguestspeakerforthe shouldbeovercomewiththetoppriorityinorder SpecialLecturefromCanada.Hegaveavery toprolonghealthlife.Strokeanddementiashare fascinatingtalkoncerebralwhitematterdisease, thesameriskfactors,andtherebytheycanbe anddeepimpressiontoaudiencesfulfilledinthe preventedsimultaneouslybycontrollingthese room(Figure1).Therewerelecturesonimaging vascularriskfactors.Basedontheseviewpoints, testsandcognitivetestsintheTeachingCourse, thetopicofthisannualmeetingwasdeterminedto whichwereveryusefulforclinicalpractice.A be“CognitiveImpairmentThoughtfromOrgan varietyoforalabstractsfrombenchtobedside Linkage”.Reflectingincreasedandexpanded werepresentedandmuchdiscussed.Iwas concerntodementia,notonlyspecialistsof impressedwithmanyparticipantsbeforethe JapaneseSocietyofNeurologyandJapanStroke presentationsofposterabstractsandenthusiastic Societybutalsomanynon-specialistsandgeneral discussion.PresentersawardedYIAwereall physiciansattended,andthetotalnumberof excellentandtalented,whowerehopesforfuture participantswasrecordedtobethelargestin ofoursociety(Figure2).Iwouldbeveryhappyif annualmeetings.InSymposium1entitled“Heart ourmessagethatdementiaispreventablealong DiseasesandDementia”,manylatestknowledges withstrokebymanagementsofvascularrisk werepresented,whichwasreputedtimelytomeet factorswasusefulforparticipantsʼclinicalpractice thetopicofthismeeting.InSymposium2entitled inpatientswithstrokeand/ordementiaaswellas “CerebralSmallVesselDisease”,frontline thosewithhugenumberofpre-strokeand/orpre- researchesandlatestreviewswerepresented dementia. regardingamyloidangiopathy,CADASILand 図1 図2 3 JAPANESESOCIETYOFVASCULARCOGNITIVEIMPAIRMENT(2018NO.4) Vas-Cog Japan 2017 Issei Komuro, MD, PhD DepartmentofCardiovascularMedicine, TheUniversityofTokyoGraduateSchoolofMedicine OnAugust5th,wehadVas-CogJapan2017at decreasedwhereasaorticstenosisandmitralvalve ToranomonHills.Thereweretotal206 regurgitationhavebeenincreased.Valvular participants,whichisthelargestnumberofVas- diseasesalsofinallyresultedinheartfailureanda CogJapan.Therewereonespeciallecture,two decreaseofbloodflowinthebraininduces symposia(1.Cardiacdiseasesanddementia,2 dementia.Thenumberofpatientsofatrial Cutting-edgeresearchofbrainmicrovascular fibrillationhasalsobeenincreasedand diseasesanddementia),YIA,threeoral cardiogeniccerebralinfarctionhasbeenincreased, presentations,twoeducationalseminars,four leadingtodementia.Therefore,thereisintimate cosponsoredseminarsandfiveposters.Prof. relationshipamongcardiovasculardiseases,stroke VladimirHachinski(TheUniversityofWestern anddementia,anditisbecomingmoreandmore Ontario)gaveusawonderfulspeciallecture importanttopromotepreventionandtreatmentfor entitled“Cognition,WhiteMatterandRedFlags” cardiovasculardiseasesandstroketoprevent andgreatlyattractedallaudience.Thiswasthe dementiatogetherwithmanyrelatedsocieties.The firsttimeformetoattendtheVas-CogJapanandI JapaneseCirculationSocietyhasmadefive-year havelearnedmanythings.Inparticular,Ichaired strategyforstrokeandcardiovasculardiseases symposium1andhaverecognizedagainthatthere withmanyrelatedsocietiesatlastyear.Inthis isintimaterelationbetweencardiacdiseasesand sensetoo,Vas-CogJapan2017wasveryimportant dementia.Therehasbeenabigchangeincardiac andhadabigmeaningforme.Iwouldliketo diseasesinJapanbybecomingsuperaging expresssincerethankstopresidentUchiyama,vice societies.Twentyyearsago,numberonecauseof presidentKitagawa,andallpeoplewhohelpedus cardiovasculardeathwasmyocardialinfarction, toholdVas-CogJapan2017aswellastoall butnowtreatmentformyocardialinfarctionhas participants. improvedanddeathratehasbeendecreased. Instead,mobilityandmortalityofheartfailure havebeenincreased.Valvulardiseasesarealso changed.Rheumaticvalvulardiseaseshavebeen 図1 図2 4 JAPANESESOCIETYOFVASCULARCOGNITIVEIMPAIRMENT(2018NO.4) Meeting report of Vas-Cog Asia 6 from Nanjing Koji Abe, MD, PhD Vas-CogAsiaPresident Iwouldliketocelebratethegreatsuccessof manyactivemembers,whichisdedicatedto Vas-CogAsia6,whichwasheldinNanjingon elucidatethemechanismofvascularfactorsin October26afternoon(2017)alwaysjointingwith Alzheimerʼsdiseaseandrelateddementia,andto Asia-PacificStrokeConference(APSC)basedonthe contributepotentialtherapyfordementiapeople greatsupportsbyProfessorYing-DongZhang inAsia.Manyvascularriskfactors(VRFs)are (APSC2017chair)andProfessorJieYang relatedtocognitivedeclineandaffective- (Nanjing).Wehad27participantsfromJapan, emotionalchangesindementiapatientsespecially Taiwan,Korea,China,HongKong,Malaysia, inelderorelderingcountriesinAsia.NextVas-Cog IndonesiaandIndia.Therewerevarietyof AsiaisgoingtobeheldinJakarta(Indonesia)on importantpresentationsinthepresentconference. September6,2018asVas-CogAsia7,andVas-Cog Manybasicscience,translationalresearch,clinical WorldisgoingtobeheldinHongKongon