31st Biennial Cornea Conference
Friday, September 20, 2019
8:00 – 8:30am Breakfast and Registration
8:30 – 8:45am Welcome and Introduction Reza Dana, MD, MPH, MSc and Ula Jurkunas, MD
8:45 – 10:50am Session 1: Ocular Surface
Moderated By: Ilene K. Gipson, PhD
8:45 – 9:05am Role of Glycosylation in Epithelial Barrier Function Pablo Argüeso, PhD Associate Professor of Ophthalmology, Harvard Medical School Senior Scientist, Schepens Eye Research Institute of Mass. Eye and Ear
9:05 – 9:25am Protection of the Ocular Surface M. Elizabeth Fini, PhD Professor of Ophthalmology Tufts University School of Medicine at Tufts Medical Center
9:25 – 9:45am The Role of the Nervous System in Oral and Ocular Organ Regeneration Sarah Knox, PhD Assistant Professor, Department of Cell & Tissue Biology University of California, San Francisco
9:45 – 10:05am A Transgenic Biosensor Mouse Model for Studying Corneal Homeostasis, Wound-Healing and Limbal Stem Cell Deficiency Nick Di Girolamo, BSc, PhD Director, Ocular Diseases Research Head, Mechanisms of Disease and Translational Research Department of Pathology, School of Medical Sciences University of New South Wales, Australia
10:05 – 10:25am Challenges in the Management of Neurotrophic Keratopathy Natalie Afshari, MD, FACS Professor of Ophthalmology Stuart I. Brown, MD, Chair in Ophthalmology in Memory of Donald P. Shiley Chief, Division of Cornea and Refractive Surgery Vice Chair of Education, Shiley Eye Institute at UC San Diego Health
10:25 – 10:50am Discussion
10:50 – 11:35am Break, Poster Viewing
11:35am – 1:15pm Session 2: Immunology and Microbiology
Moderated By: Mihaela Gadjeva, PhD, MSc Updated 8/12/19
31st Biennial Cornea Conference
11:35– 11:55am Advancing Diagnostics and Treatment of Infectious Keratitis through Innovation Paulo Bispo, PhD Assistant Scientist, Department of Ophthalmology, Harvard Medical School, Mass. Eye and Ear
11:55am – 12:15pm Contribution of Immune Responses to the Etiology of Meibomian Gland Dysfunction Daniel Saban, PhD Associate Professor of Ophthalmology and Immunology Duke University School of Medicine
12:15 – 12:35pm Lipid Mediators Unexpected Places and Functions in Ocular Health and Disease Karsten Gronert, MS, PhD Professor School of Optometry, Vision Science Program Infectious Diseases and Immunity Program University of California, Berkeley
12:35 – 12:55pm New Insights into the Host Response to Bacterial and Fungal Infections in the Cornea Eric Pearlman, PhD Professor, Departments of Ophthalmology, and Physiology and Biophysics Director, Institute for Immunology University of California, Irvine
12:55 – 1:15pm Discussion
1:15 – 2:45pm Lunch, Poster Viewing
2:45 – 3:15pm Panel 1-Areas of Greatest Unmet Need in Cornea Moderator: Albert Jun, MD, PhD Eduardo Alfonso, MD James Chodosh, MD, MPH Ilene Gipson, PhD Farhad Hafezi, MD, PhD Shigeto Shimmura, MD Vickery E. Trinkaus-Randall, PhD
3:15 – 4:30pm Session 3: Stroma
Moderated By: Sunil K. Chauhan, PhD
3:15 – 3:35pm The Perfect Storm: A New Biomarker For Keratoconus Dimitris Karamichos, PhD Associate Professor of Ophthalmology and Cell Biology W. Stanley Muenzler Professor in Corneal Disease Updated 8/12/19
31st Biennial Cornea Conference Dean McGee Eye Institute, Department of Ophthalmology, University of Oklahoma Health Sciences Center
3:35 – 3:55pm Exosomes and Corneal Cell-Cell Communication James Zieske, PhD Associate Professor of Ophthalmology, Harvard Medical School Senior Scientist, Schepens Eye Research Institute of Mass. Eye and Ear
3:55 – 4:15pm Modulating the Stromal Response to Infection: PACK-Cross-Linking Farhad Hafezi, MD, PhD Professor of Ophthalmology, University of Geneva, Switzerland Clinical Professor of Ophthalmology, Keck School of Medicine of USC Visiting Professor, University of Wenzhou, China
4:15 – 4:30pm Discussion
4:30 – 4:50pm Break
4:50 – 5:50pm J. Wayne Streilein Lecture
4:50 – 5:00pm Introduction to J. Wayne Streilein Lecture Darlene A. Dartt, PhD Professor of Ophthalmology, Harvard Medical School Senior Scientist, Schepens Eye Research Institute of Mass. Eye and Ear
5:00 – 5:50pm J. Wayne Streilein Lecture
Pseudomonas Aeruginosa Keratitis: The Long View Linda Hazlett, PhD Vice Dean for Research & Graduate Programs The Robert S. Jampel, M.D., Ph.D. Endowed Chair in Ophthalmology Distinguished Professor and Vice Chair Department of Ophthalmology, Visual and Anatomical Sciences Wayne State University School of Medicine
5:50 – 6:45pm Reception, Poster Viewing
7:00 – 9:30pm Dinner at Liberty Hotel
Updated 8/12/19
31st Biennial Cornea Conference
Saturday, September 21, 2019
8:00 – 8:30am Breakfast and Registration
8:30 – 8:35am Welcome Reza Dana, MD, MPH, MSc Claes H. Dohlman Professor of Ophthalmology Director, Cornea and Refractive Surgery Service, Mass. Eye and Ear Senior Scientist, Schepens Eye Research Institute of Mass. Eye and Ear
8:35 – 10:15am Session 4: Endothelial Biology
Moderated By: Ula Jurkunas, MD
8:35 – 8:55am Ultrastructural Characterization of Corneal Endothelium Reveals a Putative Progenitor-Enriched Niche Jodhbir Mehta, MD, PhD, FRCS (Ed) Head Corneal and External Eye Disease Service Singapore National Eye Centre Deputy Executive Director, Head Tissue Engineering & Stem Cells Group Singapore Eye Research Institute
8:55 – 9:15am Repeat RNA in Molecular Pathogenesis of Fuchs Endothelial Corneal Dystrophy V. Vinod Mootha, MD Professor of Ophthalmology Eugene McDermott Center for Human Growth and Development Paul T. Stoffel / Centex Professorship in Clinical Care University of Texas Southwestern Medical Center
9:15 – 9:35am Pluripotent Stem Cells in Disease Models and Cell Therapy Shigeto Shimmura, MD Associate Professor, Department of Ophthalmology Keio University School of Medicine, Japan
9:35 – 9:55am Progress for CRISPR-Cas9 Gene Editing as Therapy for Fuchs Corneal Dystrophy Albert Jun, MD, PhD Chief, Division of Cornea, Cataract and External Eye Diseases Walter Stark, MD, Professor of Ophthalmology Wilmer Eye Institute, Johns Hopkins School of Medicine
9:55 – 10:15am Discussion
10:15 – 10:30am Break
10:30 – 11:00am Panel 2- Controversies in Corneal Pathobiology Moderator: Reza Dana, MD, MPH, MSc
Updated 8/12/19
31st Biennial Cornea Conference Pablo Argüeso, PhD Nick Di Girolamo, BSc, PhD Pedram Hamrah, MD Noorjahan Panjwani, PhD Eric Pearlman, PhD Daniel Saban, PhD
11:00am – 12:40pm Session 5: Innovation
Moderated By: Jia Yin, MD, PhD
11:00– 11:20am Tear Cathepsin S: Biomarker and Therapeutic Target in Sjogren's Syndrome Sarah Hamm-Alvarez, PhD Professor and Vice Chair, Basic Research, Department of Ophthalmology Associate Dean, Basic and Translational Research Keck School of Medicine of USC
11:20 – 11:40am A Naturally Derived Bioadhesive Hydrogel for Corneal Sealing and Regeneration Nasim Annabi, PhD Assistant Professor Department of Chemical and Biomolecular Engineering University of California, Los Angeles
11:40am – 12:00pm What Can Tissue Engineering Tell Us About the Biology Of The Cornea? Che Connon, PhD Professor of Tissue Engineering Newcastle University, United Kingdom
12:00 – 12:20pm An Update On Dry Eye Drug Pipeline and Contact Lens Drug Delivery Joseph B. Ciolino, MD Associate Professor of Ophthalmology, Harvard Medical School; Henry Freeman Allen Cornea Scholar, Investigator, Mass. Eye and Ear
12:20 – 12:40pm Discussion
12:40 – 1:45pm Lunch, Poster Viewing
1:45 – 2:45pm Claes H. Dohlman Lecture
1:45 – 1:55pm Introduction to Claes H. Dohlman Lecture Reza Dana, MD, MPH, MSc Claes H. Dohlman Professor of Ophthalmology Director, Cornea and Refractive Surgery Service, Mass. Eye and Ear Senior Scientist, Schepens Eye Research Institute of Mass. Eye and Ear
1:55 – 2:45pm Claes H. Dohlman Lecture
Updated 8/12/19
31st Biennial Cornea Conference Multiplex Polymerase Chain Reaction Assay for Screening of Mycotoxin Genes from Ocular Isolates of Fusarium species Eduardo C. Alfonso, MD Director, Bascom Palmer Eye Institute Kathleen and Stanley J. Glaser Endowed Professor in Ophthalmology Chairman of Ophthalmology University of Miami Miller School of Medicine
2:45 – 3:00pm Closing Activities
2:45 – 2:55pm Closing Remarks: Poster Winner and Travel Award Announcement
2:55 – 3:00pm Group Photo
Updated 8/12/19