Anti-CYP4A11 (aa 229-443) polyclonal antibody (DPABH-03690) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward A1 and E1. Oxidizes to 20-hydroxyeicosatetraenoic acid (20-HETE).

Immunogen Recombinant fragment, corresponding to a region within amino acids 229-443 of Human 4A11/22 (Uniprot ID: Q02928).

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB, IHC-P, ICC/IF

Format Liquid

Size 100 μl

Buffer pH: 7.00; Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol

Preservative None

Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

GENE INFORMATION

Gene Name CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 12 [ Homo sapiens ]

Official Symbol CYP4A11

Synonyms CYP4A11; cytochrome P450, family 4, subfamily A, polypeptide 11; CP4Y; CYP4A2; CYP4AII; cytochrome P450 4A11; CYPIVA11; P450HL-omega; 20-HETE synthase; alkane-1

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved monooxygenase; cytochrome P450HL-omega; cytochrome P-450HK-omega; fatty acid omega- hydroxylase; lauric acid omega-hydroxylase; 20-hydroxyeicosatetraenoic acid synthase; cytochrome P450, subfamily IVA, polypeptide 11;

Entrez Gene ID 1579

Protein Refseq NP_000769.2

UniProt ID Q02928

Pathway Arachidonic acid metabolism; Arachidonic acid metabolism; Cytochrome P450 - arranged by substrate type; Fatty Acid Omega Oxidation

Function alkane 1-monooxygenase activity; arachidonic acid epoxygenase activity; arachidonic acid omega-hydroxylase activity; heme binding

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved