Anti-CYP4A11 (aa 229-443) polyclonal antibody (DPABH-03690) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE). Immunogen Recombinant fragment, corresponding to a region within amino acids 229-443 of Human Cytochrome P450 4A11/22 (Uniprot ID: Q02928). Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Immunogen affinity purified Conjugate Unconjugated Applications WB, IHC-P, ICC/IF Format Liquid Size 100 μl Buffer pH: 7.00; Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol Preservative None Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. GENE INFORMATION Gene Name CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 12 [ Homo sapiens ] Official Symbol CYP4A11 Synonyms CYP4A11; cytochrome P450, family 4, subfamily A, polypeptide 11; CP4Y; CYP4A2; CYP4AII; cytochrome P450 4A11; CYPIVA11; P450HL-omega; 20-HETE synthase; alkane-1 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved monooxygenase; cytochrome P450HL-omega; cytochrome P-450HK-omega; fatty acid omega- hydroxylase; lauric acid omega-hydroxylase; 20-hydroxyeicosatetraenoic acid synthase; cytochrome P450, subfamily IVA, polypeptide 11; Entrez Gene ID 1579 Protein Refseq NP_000769.2 UniProt ID Q02928 Pathway Arachidonic acid metabolism; Arachidonic acid metabolism; Cytochrome P450 - arranged by substrate type; Fatty Acid Omega Oxidation Function alkane 1-monooxygenase activity; arachidonic acid epoxygenase activity; arachidonic acid omega-hydroxylase activity; heme binding 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.