Bleeding in the Brain: Haemorrhagic Stroke
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What to Expect After Having a Subarachnoid Hemorrhage (SAH) Information for Patients and Families Table of Contents
What to expect after having a subarachnoid hemorrhage (SAH) Information for patients and families Table of contents What is a subarachnoid hemorrhage (SAH)? .......................................... 3 What are the signs that I may have had an SAH? .................................. 4 How did I get this aneurysm? ..................................................................... 4 Why do aneurysms need to be treated?.................................................... 4 What is an angiogram? .................................................................................. 5 How are aneurysms repaired? ..................................................................... 6 What are common complications after having an SAH? ..................... 8 What is vasospasm? ...................................................................................... 8 What is hydrocephalus? ............................................................................... 10 What is hyponatremia? ................................................................................ 12 What happens as I begin to get better? .................................................... 13 What can I expect after I leave the hospital? .......................................... 13 How will the SAH change my health? ........................................................ 14 Will the SAH cause any long-term effects? ............................................. 14 How will my emotions be affected? .......................................................... 15 When should -
What%Is%Epilepsy?%
What%is%Epilepsy?% Epilepsy(is(a(brain(disorder(in(which(a(person(has(repeated(seizures((convulsions)(over(time.(Seizures(are( episodes(of(disturbed(brain(activity(that(cause(changes(in(attention(or(behavior.( Causes( Epilepsy(occurs(when(permanent(changes(in(brain(tissue(cause(the(brain(to(be(too(excitable(or(jumpy.( The(brain(sends(out(abnormal(signals.(This(results(in(repeated,(unpredictable(seizures.((A(single(seizure( that(does(not(happen(again(is(not(epilepsy.)( Epilepsy(may(be(due(to(a(medical(condition(or(injury(that(affects(the(brain,(or(the(cause(may(be( unknown((idiopathic).( Common(causes(of(epilepsy(include:( •Stroke(or(transient(ischemic(attack((TIA)( •Dementia,(such(as(Alzheimer's(disease( •Traumatic(brain(injury( •Infections,(including(brain(abscess,(meningitis,(encephalitis,(and(AIDS( •Brain(problems(that(are(present(at(birth((congenital(brain(defect)( •Brain(injury(that(occurs(during(or(near(birth( •Metabolism(disorders(present(at(birth((such(as(phenylketonuria)( •Brain(tumor( •Abnormal(blood(vessels(in(the(brain( •Other(illness(that(damage(or(destroy(brain(tissue( •Use(of(certain(medications,(including(antidepressants,(tramadol,(cocaine,(and(amphetamines( Epilepsy(seizures(usually(begin(between(ages(5(and(20,(but(they(can(happen(at(any(age.(There(may(be(a( family(history(of(seizures(or(epilepsy.( Symptoms( Symptoms(vary(from(person(to(person.(Some(people(may(have(simple(staring(spells,(while(others(have( violent(shaking(and(loss(of(alertness.(The(type(of(seizure(depends(on(the(part(of(the(brain(affected(and( cause(of(epilepsy.( -
Brain Injury and Opioid Overdose
Brain Injury and Opioid Overdose: Acquired Brain Injury is damage to the brain 2.8 million brain injury related occurring after birth and is not related to congenital or degenerative disease. This includes anoxia and hospital stays/deaths in 2013 hypoxia, impairment (lack of oxygen), a condition consistent with drug overdose. 70-80% of hospitalized patients are discharged with an opioid Rx Opioid Use Disorder, as defined in DSM 5, is a problematic pattern of opioid use leading to clinically significant impairment, manifested by meaningful risk 63,000+ drug overdose-related factors occurring within a 12-month period. deaths in 2016 Overdose is injury to the body (poisoning) that happens when a drug is taken in excessive amounts “As the number of drug overdoses continues to rise, and can be fatal. Opioid overdose induces respiratory doctors are struggling to cope with the increasing number depression that can lead to anoxic or hypoxic brain of patients facing irreversible brain damage and other long injury. term health issues.” Substance Use and Misuse is: The frontal lobe is • Often a contributing factor to brain injury. History of highly susceptible abuse/misuse is common among individuals who to brain oxygen have sustained a brain injury. loss, and damage • Likely to increase for individuals who have misused leads to potential substances prior to and post-injury. loss of executive Acute or chronic pain is a common result after brain function. injury due to: • Headaches, back or neck pain and other musculo- Sources: Stojanovic et al 2016; Melton, C. Nov. 15,2017; Devi E. skeletal conditions commonly reported by veterans Nampiaparampil, M.D., 2008; Seal K.H., Bertenthal D., Barnes D.E., et al 2017; with a history of brain injury. -
Traumatic Brain Injury and Domestic Violence
TRAUMATIC BRAIN INJURY AND DOMESTIC VIOLENCE Women who are abused often suffer injury to their head, neck, and face. The high potential for women who are abused to have mild to severe Traumatic Brain Injury (TBI) is a growing concern, since the effects can cause irreversible psychological and physical harm. Women who are abused are more likely to have repeated injuries to the head. As injuries accumulate, likelihood of recovery dramatically decreases. In addition, sustaining another head trauma prior to the complete healing of the initial injury may be fatal. Severe, obvious trauma does not have to occur for brain injury to exist. A woman can sustain a blow to the head without any loss of consciousness or apparent reason to seek medical assistance, yet display symptoms of TBI. (NOTE: While loss of consciousness can be significant in helping to determine the extent of the injury, people with minor TBI often do not lose consciousness, yet still have difficulties as a result of their injury). Many women suffer from a TBI unknowingly and misdiagnosis is common since symptoms may not be immediately apparent and may mirror those of mental health diagnoses. In addition, subtle injuries that are not identifiable through MRIs or CT scans may still lead to cognitive symptoms. What is Traumatic Brain Injury? Traumatic brain injury (TBI) is defined as an injury to the brain that is caused by external physical force and is not present at birth or degenerative. TBI can be caused by: • A blow to the head, o e.g., being hit on the head forcefully with object or fist, having one’s head smashed against object/wall, falling and hitting head, gunshot to head. -
Traumatic Brain Injury (TBI)
Traumatic Brain Injury (TBI) Carol A. Waldmann, MD raumatic brain injury (TBI), caused either by blunt force or acceleration/ deceleration forces, is common in the general population. Homeless persons Tare at particularly high risk of head trauma and adverse outcomes to TBI. Even mild traumatic brain injury can lead to persistent symptoms including cognitive, physical, and behavioral problems. It is important to understand brain injury in the homeless population so that appropriate referrals to specialists and supportive services can be made. Understanding the symptoms and syndromes caused by brain injury sheds light on some of the difficult behavior observed in some homeless persons. This understanding can help clinicians facilitate and guide the care of these individuals. Prevalence and Distribution recover fully, but up to 15% of patients diagnosed TBI and Mood Every year in the USA, approximately 1.5 with MTBI by a physician experience persistent Swings. million people sustain traumatic brain injury disabling problems. Up to 75% of brain injuries This man suffered (TBI), 230,000 people are hospitalized due to TBI are classified as MTBI. These injuries cost the US a gunshot wound and survive, over 50,000 people die from TBI, and almost $17 billion per year. The groups most at risk to the head and many subsequent more than 1 million people are treated in emergency for TBI are those aged 15-24 years and those aged traumatic brain rooms for TBI. In persons under the age of 45 years, 65 years and older. Men are twice as likely to sustain injuries while TBI is the leading cause of death. -
Rapidly Progressive Tetraplegia and Cognitive Deterioration During Rehabilitation: a Case of Neurodegenerative Disease
J Surg Med. 2019;3(1):100-102. Case report DOI: 10.28982/josam.454181 Olgu sunumu Rapidly progressive tetraplegia and cognitive deterioration during rehabilitation: A case of neurodegenerative disease Rehabilitasyon sırasında hızlı ilerleyen tetrapleji ve bilişsel bozulma: Bir nörodejeneratif hastalık olgusu Sevgi İkbali Afşar 1, Oya Ümit Yemişçi 1 1 Department of Physical Medicine and Abstract Rehabilitation, Baskent University, Human prion diseases are fatal, progressive neurodegenerative disorders caused by neurolytic pathogen proteins, called Faculty of Medicine, Ankara, Turkey prions. The most common human prion disease is sporadic Creutzfeldt-Jakob disease, with an approximate annual prevalence of 0.5-1 per million. The symptoms and signs include rapidly progressive dementia, ataxia, myoclonic ORCID ID of the authors SİA: 0000-0002-4003-3646 seizures, akinetic mutism and other neurological and neurobehavioral disorders. The clinical spectrum of Creutzfeldt- OÜY: 0000-0002-0501-5127 Jakob disease is highly variable; therefore it can be difficult to diagnose premortem. This article describes a 78-year- old woman who initially presented with difficulty walking and balance disorder. As a result of the evaluation, the patient was transferred to rehabilitation clinic, with a diagnosis of cervical spinal stenosis. During hospitalization, she showed progressive decline in gait and balance and deteriorated rapidly. The patient was considered to be probable sporadic Creutzfeldt-Jakob disease after further investigations. Keywords: Neurodegenerative disease, Creutzfeldt-Jakob disease, Rehabilitation Öz Corresponding author / Sorumlu yazar: İnsan prion hastalıkları, prionlar olarak adlandırılan nörolitik patojen proteinlerin neden olduğu ilerleyici Sevgi İkbali Afşar Address / Adres: Fevzi Cakmak Cad. 5. Sokak nörodejeneratif hastalıklardır. En yaygın insan prion hastalığı sporadik Creutzfeldt-Jakob hastalığı olup, yıllık No: 48, 06490, Ankara, Türkiye prevalansı yaklaşık milyonda 0.5-1'dir. -
Guidelines for the Management of Severe Traumatic Brain Injury 4Th Edition
Guidelines for the Management of Severe Traumatic Brain Injury 4th Edition Nancy Carney, PhD Oregon Health & Science University, Portland, OR Annette M. Totten, PhD Oregon Health & Science University, Portland, OR Cindy O'Reilly, BS Oregon Health & Science University, Portland, OR Jamie S. Ullman, MD Hofstra North Shore-LIJ School of Medicine, Hempstead, NY Gregory W. J. Hawryluk, MD, PhD University of Utah, Salt Lake City, UT Michael J. Bell, MD University of Pittsburgh, Pittsburgh, PA Susan L. Bratton, MD University of Utah, Salt Lake City, UT Randall Chesnut, MD University of Washington, Seattle, WA Odette A. Harris, MD, MPH Stanford University, Stanford, CA Niranjan Kissoon, MD University of British Columbia, Vancouver, BC Andres M. Rubiano, MD El Bosque University, Bogota, Colombia; MEDITECH Foundation, Neiva, Colombia Lori Shutter, MD University of Pittsburgh, Pittsburgh, PA Robert C. Tasker, MBBS, MD Harvard Medical School & Boston Children’s Hospital, Boston, MA Monica S. Vavilala, MD University of Washington, Seattle, WA Jack Wilberger, MD Drexel University, Pittsburgh, PA David W. Wright, MD Emory University, Atlanta, GA Jamshid Ghajar, MD, PhD Stanford University, Stanford, CA Reviewed for evidence-based integrity and endorsed by the American Association of Neurological Surgeons and the Congress of Neurological Surgeons. September 2016 TABLE OF CONTENTS PREFACE ...................................................................................................................................... 5 ACKNOWLEDGEMENTS ............................................................................................................................................. -
Influence of Mild Hypothermia on Hypoxic- Ischemic Brain Damage in the Immature Rat
003 I-399X/s 113404-0525$03.00/0 PEDIATRIC RESEARCH Vol. 34. No. 4. 1993 Copyright fc 1993 lnternat~onalPedlatnc Research Foundat~on.Inc. Prrt~rc~drn Lr.S..4. Influence of Mild Hypothermia on Hypoxic- Ischemic Brain Damage in the Immature Rat J. YAGER. J. TOWFIGHI. AND R. C. VANNUCCl Di,puritno~ic~l'Pi~cliciirii~.s /J. Y/. Roj.ul L'nivcrsii! IIo.spiiul. L'ni~~c,r.sii!*c~f'Su.sX.uic~lrc~~~~ut~, Su.skuioot~. Su.sku~chc~c~ut~,C'ut~udu. S7N 0x0: and D(~purrtnenrc~f'Purhol~~s.!~ (Nnrroputllok~g~ /J. T.1 und Pc~diuiricA'~,r~ro/ox~~ /R.('. I,./. 7%i, .l/iliot~S. Ilcr.sl~c,!~hI(~dicu1 ('cwrc~r. Tlli. Pi~t~n.s~-l~~unicrSiurc Crni~~c,r.vit!~. IIi~r.s/rc~~~.Pc~t~t~.s~~/vut~iu 17033 ABSTRACT. Recent studies in adult animals have shown mia also is protective (8. 9). Conversely. hyperthermia either that even small decreases in brain or core temperature during or after an hypoxic-ischemic insult worsens ultimate brain ameliorate the damage resulting from hypoxic-ischemic damage (lo, l I). insults. To determine the effect of minor reductions in In contrast to the adult. the human term infant. under physi- ambient temperature either during or after an hypoxic- ologic circumstances can maintain thermal neutrality only over ischemic insult on the brain of the immature rat, 7-d- a severely restricted range of environmental temperatures ( 12- postnatal rat pups underwent unilateral common carotid 15). Infants, who are frequently exposed to a variety of "stresses" artery ligation followed by exposure to hypoxia in 8% (birth asphyxia. -
Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives
International Journal of Molecular Sciences Review Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives Diji Kuriakose and Zhicheng Xiao * Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne, VIC 3800, Australia; [email protected] * Correspondence: [email protected] Received: 29 September 2020; Accepted: 13 October 2020; Published: 15 October 2020 Abstract: Stroke is the second leading cause of death and a major contributor to disability worldwide. The prevalence of stroke is highest in developing countries, with ischemic stroke being the most common type. Considerable progress has been made in our understanding of the pathophysiology of stroke and the underlying mechanisms leading to ischemic insult. Stroke therapy primarily focuses on restoring blood flow to the brain and treating stroke-induced neurological damage. Lack of success in recent clinical trials has led to significant refinement of animal models, focus-driven study design and use of new technologies in stroke research. Simultaneously, despite progress in stroke management, post-stroke care exerts a substantial impact on families, the healthcare system and the economy. Improvements in pre-clinical and clinical care are likely to underpin successful stroke treatment, recovery, rehabilitation and prevention. In this review, we focus on the pathophysiology of stroke, major advances in the identification of therapeutic targets and recent trends in stroke research. Keywords: stroke; pathophysiology; treatment; neurological deficit; recovery; rehabilitation 1. Introduction Stroke is a neurological disorder characterized by blockage of blood vessels. Clots form in the brain and interrupt blood flow, clogging arteries and causing blood vessels to break, leading to bleeding. -
Understanding Seizures and Epilepsy
Understanding Sei zures & Epilepsy Selim R. Benbadis, MD Leanne Heriaud, RN Comprehensive Epilepsy Program Table of Contents * What is a seizure and what is epilepsy?....................................... 3 * Who is affected by epilepsy? ......................................................... 3 * Types of seizures ............................................................................. 3 * Types of epilepsy ............................................................................. 6 * How is epilepsy diagnosed? .......................................................... 9 * How is epilepsy treated? .............................................................. 10 Drug therapy ......................................................................... 10 How medication is prescribed ............................................ 12 Will treatment work?............................................................ 12 How long will treatment last?............................................. 12 Other treatment options....................................................... 13 * First aid for a person having a seizure ....................................... 13 * Safety and epilepsy ....................................................................... 14 * Epilepsy and driving..................................................................... 15 * Epilepsy and pregnancy ............................................................... 15 * More Information .......................................................................... 16 Comprehensive -
Part Ii – Neurological Disorders
Part ii – Neurological Disorders CHAPTER 19 HEAD AND SPINAL INJURY Dr William P. Howlett 2012 Kilimanjaro Christian Medical Centre, Moshi, Kilimanjaro, Tanzania BRIC 2012 University of Bergen PO Box 7800 NO-5020 Bergen Norway NEUROLOGY IN AFRICA William Howlett Illustrations: Ellinor Moldeklev Hoff, Department of Photos and Drawings, UiB Cover: Tor Vegard Tobiassen Layout: Christian Bakke, Division of Communication, University of Bergen E JØM RKE IL T M 2 Printed by Bodoni, Bergen, Norway 4 9 1 9 6 Trykksak Copyright © 2012 William Howlett NEUROLOGY IN AFRICA is freely available to download at Bergen Open Research Archive (https://bora.uib.no) www.uib.no/cih/en/resources/neurology-in-africa ISBN 978-82-7453-085-0 Notice/Disclaimer This publication is intended to give accurate information with regard to the subject matter covered. However medical knowledge is constantly changing and information may alter. It is the responsibility of the practitioner to determine the best treatment for the patient and readers are therefore obliged to check and verify information contained within the book. This recommendation is most important with regard to drugs used, their dose, route and duration of administration, indications and contraindications and side effects. The author and the publisher waive any and all liability for damages, injury or death to persons or property incurred, directly or indirectly by this publication. CONTENTS HEAD AND SPINAL INJURY 413 EPIDEMIOLOGY � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � -
Head Injury for Neurologists *
J Neurol Neurosurg Psychiatry: first published as 10.1136/jnnp.73.suppl_1.i8 on 1 September 2002. Downloaded from HEAD INJURY FOR NEUROLOGISTS Richard Greenwood i8* J Neurol Neurosurg Psychiatry 2002;73(Suppl I):i8–i16 rauma is the leading cause of death and long term disablement in young persons. Head injury accounts for about 30% of traumatic deaths and a higher proportion of long term disablement. THistorically the emphasis of reviews on head injury has concentrated on the acute phase of treatment and has thus adopted a neurosurgical perspective. As a result, much of the content is peripheral to neurological practice, and the consequences of traumatic brain injury (TBI) remain the business of somebody, and as a result nobody, else. An underlying assumption is presumably that anyone can diagnose injury to the head, which is usually true, but determining whether, and to what extent, coexisting injury to the brain contributes to a clinical problem may not be so sim- ple. A night in an accident and emergency department, neurological consultations on the intensive therapy unit or general or psychiatric wards, or involvement in a personal injury case will soon make this evident. Neurological contact with patients with TBI is likely to increase with developing interest in neuro- protection and restorative neurology, drug treatments of specific impairments, increasing evidence of effectiveness of rehabilitation programmes after TBI,1 and improved methods of imaging dem- onstrating evolving and residual brain damage. This paper aims to describe the sequelae of TBI that impact on current and future neurological practice. A detailed discussion of its rehabilitation is omitted.