CURRICULUM VITAE

Dr. Ibrahim Hamza Kankia, MRSB BSc (UDUS), MSc (UK), PhD (UK)

Emails: Mobile : [email protected] +447447181221 [email protected] +447466347529 [email protected] +2348066225056 [email protected]

Permanent Home Address: Unguwar Kanawa Kankia, State. Correspondence Address: Department of Biochemistry, Umaru Musa Yar’adua University, 2218, – .

Qualification: PhD Molecular and Cellular Pharmacology

Area of Specialization: Molecular, Biotechnological and Pharmacological approaches to improving breast and ovarian cancer therapy

Experience: Academic (Teaching/Research) & Non-academic (Academic Planning)

Applications and techniques used in my research: 1. Bioinformatics 2. DNA/RNA Isolation, 3. PCR, and RTPCR 4. Molecular Cloning and Gene delivery, 5. Expression and Trafficking Analysis; 6. Gene Promoter Constructs and Reporter Assays; 7. Biochemical Techniques involving Protein Expression and Characterisation (Extraction, Quantification and Purification) 8. ELISA based assays; 9. Fluorescence and Luminescence based assays; 10. Immuno-detection techniques including Western blotting, Immunocytochemistry 11. Cell culture Techniques (2D & 3D) and Stable cell lines; 12. Cell Viability/Cytotoxicity Assays such as MTT and MTS assays and 13. Drug Internalisation and Metabolism Assays, etc

Research Interest My research interest involves the use of monoclonal antibodies and small molecule inhibitors for the treatment of cancer. Drug resistance is a major challenge in cancer research, since it limits the efficacy of most current cancer therapy. The resistance to a drug may be intrinsic or acquired during administration and may account for more than 90% of treatment failure in patients with metastatic cancer. There is need to

discover and develop new molecules or strategies with anticancer efficacy. In the past novel anticancer principles like single or combined drug treatments have been used. My research will follow such tract to explore, and develop anticancer principles by reprograming some genes and inhibiting some signaling pathways. Then use recombinant DNA technology, tissue culture, microscopy, immunohistochemistry and enzymes assay techniques to study cancer cells dynamics/survivorship and to inform treatment design and efficacy of these anticancer principles from reprograming of genes and inhibition of certain signaling pathways like that of EGFR and NRF2.

Objective To offer first class solutions that will boost the accomplishments of

my institution’s goal and develops my skills for thorough success.

Personal Profile Date of Birth 10th October, 1982 Age 35 Marital Status Married Number of Children 2 Local Govt. Kankia State of Origin. Katsina Nationality Nigeria

Summary of 2014-2017 University of Abertay, Dundee, Scotland, UK institutions PhD Molecular and Cellular Pharmacology attended with dates, and 2012-2013 University of Chester, United Kingdom qualifications M Sc. Biomedical Science

2002-2005 Usmanu Danfodiyo University Sokoto B sc. Biochemistry

1995-2000 Govt. Sci. Sec. Sch. Dutsin-ma Katsina State Senior Secondary School Certificate

1988-1994 Nuhu Model Pri. Sch. Kankia Katsina State First School Leaving Certificate

2007-2008 Ubong Etuk Computer Center Akwa Ibom Diploma in Computer Application

Professional 2007 Nigerian Institute of Management Qualifications Certificate

Assistant Lecturer, Present Position Department of Biochemistry, Umaru Musa Yar’adua University, Katsina, Nigeria

List of Researches/on- 1. Ibrahim H. Kankia, Hilal S. Khalil, Simon P. Langdon, going and yet to Peter R. Moult, David J. Harrison James L. Bown, and be published Yusuf Y. Deeni 'NRF2 Regulates HER4 Signalling Pathway in Ovarian Cancer Cells (In preparation for

submission).

2. Ibrahim H. Kankia, Hilal S. Khalil, Simon P. Langdon, Peter R. Moult, David J. Harrison James L. Bown, and Yusuf Y. Deeni 'Targetting HER4 Signalling Pathway to Modulate the Sensitivity of Ovarian Cancer Cells to RTK Chemotherapy (In preparation for submission).

3. Phytochemical screening and effect of Datura metel aqueous seed extract on some kidney function indices in albino rats (June, 2011- Sept., 2011)

4. Phytochemical screening and anticancer effects of some certain medicinal plants (Sept., 2010-August, 2014).

5. Beneficial effects of aloe vera and honey on trichlorfon

induced some biochemical modifications in experimental rats

6. Effect of Honey (Apis Melifera) on Serum glucose level of diabetic and non-diabetic induced rats.

7. Influence of Blood Group on Fertility “A case study of Middle aged women attending Kankia General Hospital”

8. Hypoglycemic Effect of Aloe Vera Extract on streptozocin induced diabetic Experimental rats.

Selected Publications 1. Ibrahim H. Kankia, Hilal S. Khalil, Simon P. Langdon, Peter R. Moult, David J. Harrison James L. Bown, and Yusuf Y. Deeni 'NRF2 Regulates HER1 Signalling Pathway to Modulate the Sensitivity of Ovarian Cancer Cells to Lapatinib and Erlotinib', Oxidative Medicine and Cellular Longevity, Oxidative Medicine and Cellular Longevity (ACCEPTED, IN

PRESS).

2. Hilal S. Khalil, Simon P. Langdon, Ibrahim H. Kankia, James Bown, and Yusuf Y. Deeni (2016) 'NRF2 Regulates HER2 and HER3 Signalling Pathway to Modulate Sensitivity to Targeted Immunotherapies', Oxidative Medicine and Cellular

Longevity, pp. 22. http://dx.doi.org/10.1155/2016/4148791

3. Isah Musa Fakai1, Lukman Ango, Abubakar Abdulhamid, Ibrahim Sani, Ibrahim Hamza Kankia (2016). Alterations in Marker Enzymes and Kidney Function Indices Following Administration of Datura metel Aqueous Seed Extract in Albino Rats. International Journal of Biomedical and Clinical Sciences. Vol. 1, No. 1, 2016, pp. 7-13. http://www.aiscience.org/journal/ijbcs

4. Kankia, I. H (2015). Immunomodulatory effects of carbohydrates and advanced glycation end products. Academic Journals, Biotechnology and Molecular Biology

Reviews. Vol. 10(1), pp. 1-11, January 2015 DOI: 10.5897/BMBR2014-0237 ISSN 1538-2273 http://www.academicjournals.org/BMBR

5. Kankia, H. I., Zainab, S. A (2015). Phytochemical Analysis and Antimicrobial Activity of Methanolic and Ethanolic Leaves, Barks and Roots Crude Extracts of Khaya Senegalensis. International Journal of Scientific and Research Publications (IJSRP), Volume 5, Issue 1, January 2015 Edition [ISSN 2250-3153], http://www.ijsrp.org/research-paper- 0115.php?rp=P373591

6. Kankia, I. H. (2015) Determination of the effects of Complex Carbohydrates on Cytokine status of Monocytes. International Journal of Current Research, Vol. 7, Issue, 01, pp.11858-11865, January, 2015

7. Kankia, I. H. (2014). Phytochemical Screening and Antibacterial Activities of Leaf Extracts of Terminalia catappa (Umbrella Tree). International Journal of Science and Research (IJSR), ISSN (Online): 2319-7064. Volume 3 Issue 12, December 2014.

8. Kankia, I. H., Safiyya Y. S (2014). Pregnancy Complications and Mental Health Related Problems Associated With Type 2 Diabetic Patients Attending General Hospital Katsina,

Nigeria. International Journal of Science and Research (IJSR), ISSN (Online): 2319-7064. Volume 3 Issue 12, December 2014.

9. Suleiman, M., Kankia, I. H and Sani, Z. (2014) Efficacy of Euphorbia balsamifera L. and Jotropha curcas L. leaf powders against Callosbrucus maculatus F. [Coleoptera: bruchidae. European Journal of Zoological Research, 2014, 3 (3):15-20 10. Kankia I. H., Zainab S. A. and Fakai I. M. (2014) Effects of complex carbohydrates on Human monocytes. Proceedings of International Conference on Science and Sustainable Development, Vol. 6. Number 1, University Auditorium, University of Lome, Lome, Togo (July 14-17, 2014) 11. Kankia, I. H. (2014). Phytochemical analysis and antimicrobial activity of crude extract of Datura metel

leaves. Scholarly Research Library. Archives of Applied Science Research, 2014, 6 (6):138-143

Selected 1. 22nd World Congress on Advances in Oncology and 20th Conferences / International Symposium on Molecular Medicine is organized Seminars/ by Spandidos Publications and would be held during Oct 05 - Workshops 07, 2017 at Metropolitan Hotel, Athens, Attica, Greece. attended 2. Beatson International Cancer Conference, FEEDING THE BEAST - The Metabolic Landscape of the Tumour and its Host, 2-5 July 2017, Glasgow, Scotland 3. Postgraduate Research Student Conference held on 20 -21 July, 2017, Abertay University Dundee, UK

4. Cell Symposia: Cancer, Inflammation, and Immunity, June 11- 13, 2017-San Diego, CA, USA 5. Abertay University Postgraduate Research Seminar held on 16th February, 2017, Abertay University, UK

6. Abertay University Postgraduate Research Seminar held on 25th November, 2016, Abertay University, UK

7. University of Dundee School of Medicine Research Symposium

held on 10th November, 2016, University of Dundee, UK 8. Postgraduate Research Student Conference Wednesday 9 and Thursday 20 October, 2016, Abertay University Dundee nd 9. 2 Congress of Polish Biochemistry, Cell biology, Biotechnology and Bioinformatics “Bio2016, September, 2016 At Wroclaw, Poland 10. 2nd International conference on CLINICAL SCIENCES AND DRUG DISCOVERY held on 27-29 July, 2016 in Dundee, United Kingdom.

11. Postgraduate Research Student Conference held on 29 -30 June,

2016, Abertay University Dundee, UK

12. 17th International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants, Redox World Congress, At Paris, Volume: Journal of ISANH Volume 3: Special Issue for Paris Redox 2016 (2016)

13. Abertay University Postgraduate Research Seminar held on

17th March, 2016, Abertay University, UK

14. Abertay University Postgraduate Research Seminar held on 19th November, 2015, Abertay University, UK

15. Abertay University Postgraduate Research Seminar held on 11th February, 2015, Abertay University, UK 16. Nigerian Society for Microbiology, 37th Annual Conference and General Meeting, Zaria (2-5th September, 2014)

17. Parasitology and Public Health Society of Nigeria, thirty eight annual conference, University of Nigeria, Nsukka (Sept,. 16-19, 2014)

18. 11th International Conference on sustainable Development, University Auditorium, University of Lome, Lome, Togo (July 14-17, 2014) 19. Nigerian Society of Biochemistry and molecular biology, 31st annual conference University of Nsukka 2011. 20. 2010 Workshop and Annual Meeting of Committee OF Directors of Academic Planning of Nigerian Universities (CODAPNU)

UG Projects 1. Assessment of heavy metals in benthic invertebrates found at Supervised Ajiwa Dam, Katsina State (2013). 2. Co-infection of malaria and typhoid fevers among pregnant women attending General Hospital (2013). 3. Prevalence on urinary schistomiasis in model school in Ajiya, Batagarawa, Katsina State (2013).

4. Pregnancy complications and mental health related problems associated with type 2 diabetic patients attending General Hospital Katsina (2013).

Practical Skills Office packages, Ms Word, Excel, Access, Internet browsing, ability to solve problems concerning laboratory practicals etc

Work experience 2014 TO DATE ASSISTANT LECTURER DEPARTMENT OF BIOCHEMISTRY UMARU MUSA YAR’ADUA UNIVERSITY, KATSINA. NIGERIA.

2012 TO 2013 GRADUATE ASSISTANT DEPARTMENT OF BIOCHEMISTRY UMARU MUSA YAR’ADUA UNIVERSITY, KATSINA. NIGERIA.

2009-2012 ACADEMIC PLANNING OFFICER UMARU MUSA YAR’ADUA UNIVERSITY, KATSINA. NIGERIA. The duties involved include:

1. To plan, guide and monitor the university's activities in accordance with the statutory goals, mission and vision of the university. 2. Enrolment Projection and Assessment needs as basis for resource allocation in the University 3. Using information on University academic materials and facilities for planning 4. Preparation of National Universities Commission (NUC) Annual Estimates for the University 5. Annual updating, analysis and interpretation of data for the planning, preparation of the University budget and subsequent resource allocation within the ambit of the approved budget 6. Searching/Soliciting for Fellowships, Scholarships, Technical Assistance, External Aids etc for staff to enhance teaching, research and development 7. Determination of adequate staff strength and requirement to guide against any possible excess staffing and its attendant results 8. Sourcing for linkages and collaborations with other Universities/Institutions/Organizations in order to exchange collegiality across the globe 9. Preparation of the University Rolling Plans in conjunction with the Physical Planning Unit 10. Preparation of Strategic Plan and ensuring University’s compliance with the provisions of the plan in its implementation 11. Preparation, implementation and general review of Academic Brief, etc

2007-2009 PART-TIME LECTUREE SCHOOL OF HEALTH TECHNOLOGY KANKIA Taught Health Sciences related course

2006/2007 NATIONAL YOUTH SERVICE CORPS Federal Govt. College Ikot Ekpene Akwa Ibom Involved in Chemistry practical session with senior students in volumetric and Qualitative Analysis. Taught junior students Integrated Science on both theoretical and Practical Session. Taught senior students Biology and Chemistry theory.

2005 STUDENT INDUSTRIAL WORK EXPERIENCE SCHEME (SIWES) Medical Laboratory Science Department (F.M.C) Katsina. Trained on how to collect samples e.g. Blood, Fluids etc in reception room. Trained on how to carry out different tests, like Blood grouping, Cross Matching, Packed Cell Volume (PCV), Full Blood Count (FBC), Stool M/C/S, Urine M/C/S, HIV test, Pregnant test, Random Blood Sugar (RBS), Electrolytes, Hormones test among others in their respective units.

Responsibilities Held 1. Member, Departmental research and special projects committee (January, 2014)

2. Secretary, Departmental admission committee (October, 2013 to Sept, 2014) 3. Level coordinator (2013 to 2014) 4. Assistant Examination Officer, Department of Biochemistry (2014) 5. Member, Laboratory Committee, Department of Biochemistry (2013 to 2014)

6. Academic Planning Officer, Directorate of Academic Planning, UMYUK (2009-2012)

Membership/ Service to 1. Member, Royal Society of Biology (MRSB) community/ 2. Member, American Society for Biochemistry and Molecular Volunteer Biology (ASBMB) Experiences 3. Member, Nigerian Society of Biochemistry and Molecular Biology (NSBMB)

4. Chairman Kankia Student Development Association (KASDA) 5. NYSC/UNICEF HIV/AIDS Training Programme

6. Organized evening lectures for the Student of School Health Technology, Kankia, Katsina State.

7. Organized evening classes for the Candidate preferring for WASSCE/NECO November/December External Examinations

8. Member Kankia Football Association (KAFA)

Personal Humility, Diligence, Impeccable Honest Character, Communication skills Initiative and Innovative Qualities

Interests and Reading, Teaching, Research, Writing, Traveling, Meeting People, activities Foot Ball and Volley Ball.

References Dr. Nasiruddeen Umar Head of Department, Biochemistry Umaru Musa Yar’adua University, Katsina P.M.B 2218, Katsina Email: [email protected]

Dr. Yusuf Deeni Director Research Degrees, School of Science, Engineering and Technology, University of Abertay, Dundee, Scotland United Kingdom E-mail: [email protected]

Professor John H. H. Williams Sub-Dean Postgraduate school, University of Chester, United Kingdom E-mail: [email protected]

Professor M.G. Abubakar Dean Faculty of Science, Usmanu Danfodiyo University, Sokoto, Nigeria 08035052912 E-mail: [email protected]