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Following Abstracts Were Not Provided I Onda Ih Impressum PUBLISHER: ISABS – International Society for Applied Biological Sciences CIRCULATION: 500 copies Zagreb, June 2011 Copyright 2011 Video and/or audio-taping of any session is not permitted without prior approval from the speakers and from the scientific committee of the 7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine 7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine 1 June 20-24, 2011, Bol, Island of Braþ, Croatia Conference floor layout Braè Executive bar Press center WC Hvar Šolta Korèula WC Entrance Bar Ela Vis Souvenir shop Reception Restaurant Wellness Bowling Tavern “Vallum” Night club 7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine 2 June 20-24, 2011, Bol, Island of Braþ, Croatia Table of Contents Table of Contents Welcome note …………………………………………………. 4 Conference Organizer ……………………………………….. 5 ISABS Committees …………………………………………… 7 The Young Investigator Awards…….. ……………………... 10 Scientific Program Information …………………………….. 11 General Information ………………………………………….. 13 Speakers ……………………………………………………….. 15 Scientific Program ……………………………………………. 20 Abstracts – Oral Presentations ……………………………. 30 Invited Lectures ………………………………………………… 31 Technial Workshop………………………………………………87 Selected Lectures ……………………………………………… 91 YIA ……………………………………………………………….. 96 Abstracts – Poster Presentations …………………………. 101 Forensic Genetics ……………………………………………… 102 Anthropologic Genetics .……………………………………….. 142 Medical Genetics ……………….………………………………. 167 About Invited Speakers . …………………………………….. 219 HDHG Scientific Program …………………………………… 236 Abstracts – Oral Presentations…...………………………… 242 Abstracts – Poster Presentations…...…...………………… 280 Sponsor’s Information ……………………………………….. 305 Author index …………………………………………………… 318 Keyword index ………………………………………………… 328 7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine 3 June 20-24, 2011, Bol, Island of Braþ, Croatia Welcome note Welcome note Dear Colleagues, Welcome to the 7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine. The conference is next in the series of biennial events organized by the International Society for Applied Biological Sciences, a society dedicated to the promotion of applied molecular biology (www.isabs.hr). Since the initiation of the series in 1997, we have strived both to focus and broaden the scope of the conferences. The focus has been on the application of cutting- edge analytical methodology in forensic science. However, since 2007 we have broadened the area of interest by the introduction of molecular anthropology that, in large part, shares the methodology with forensic genetics. In 2009, we introduced selected topics from individualized medicine, another applied discipline based on the advances in mapping of the human genome. In 2011 we decided to include the newest and most interesting topics related to the molecular medicine. As before, the conference is structured to allow close interaction of the international faculty and attendees. Together with formal presentations, there will be meet-the- professor sessions, a day trip and other social occasions that are meant to enhance opportunities for scientific intercourse, but also to introduce the participants to the town of Bol, one of the best known tourist destinations in Croatia due to its unspoiled nature, beautiful beaches, cultural and historical attractions and well developed tourist and sport offers. Enjoy! Moses Schanfield Dragan Primorac Stanimir Vuk-Pavloviü Program/Conference Directors 7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine 4 June 20-24, 2011, Bol, Island of Braþ, Croatia Conference Organizer CONFERENCE ORGANIZER Organizer: International Society for Applied Biological Sciences e-mail: [email protected] http://www.isabs.hr Conference is organized under the auspices of the Croatian Academy of Science and Arts Program/Conference Directors: Moses Schanfield, George Washington University, Washington, DC, USA Dragan Primorac, University of Split and University of Osijek, Croatia; The Pennsylvania State University and University of New Haven, USA Stanimir Vuk-Pavloviü, Mayo Clinic College of Medicine, Rochester, MN, USA Program Committee: Gordan Lauc (Genos, Ltd, DNA Laboratory, Zagreb, Croatia) Damir Marjanoviü (Institute for Genetic Engineering and Biotechnology (INGEB), Sarajevo, Bosnia and Herzegovina and Genos and Forensic DNA Laboratory, Zagreb, Croatia) Pavao Rudan (University of Zagreb, Zagreb, Croatia) Stanimir Vuk-Pavloviü (Mayo Clinic College of Medicine, Rochester, MN, USA) Scientific Committee: Forensic Genetics: Antonio Alonso (National Institute of Toxicology and Forensic Sciences, Madrid, Spain) Zoran Budimlija (Office of Chief Medical Examiner, New York, NY, USA) Cecelia Crouse (Palm Beach Sheriff's Office, West Palm Beach, FL, USA) Jürgen Henke (Institut für Blutgruppenforschung, Köln, Germany) Mitchell Holland (The Pennsylvania State University, USA) Henry Lee (University of New Haven, West Haven and Connecticut Forensic Science Laboratory, Meriden, CT, USA) José Antonio Lorente (Pfizer - University of Granada & Andalusian Government Centre for Genomics & Oncology, Granada, Spain) Marilyn Menotti-Raymond (National Cancer Institute, Frederick, MD, USA) Antti Sajantila (Department of Forensic Medicine, University of Helsinki, Helsinki, Finland) Molecular and Cellular Medicine: Henry Erlich (Roche Molecular Systems, Inc., Alameda, CA, USA) 7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine 5 June 20-24, 2011, Bol, Island of Braþ, Croatia Conference Organizer Francis Glorieux (Genetics Unit, Shriners Hospital for Children and McGill University, Montreal, QC, Canada) Robert Huber - Nobel Laureate 1988 (Max Planck Institute for Biochemistry, Martinsried, Germany) Doron Lancet (Weizmann Institute of Science, Rehovot, Israel) Gordan Lauc (Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia) Pier Franco Pignatti (Institute of Biology and Genetics and Faculty of Medicine and Surgery, University of Verona, Italy) Richard J. Roberts - Nobel Prize 1993 (New England Biolabs, Ipswich, MA, USA) Igor Rudan (University of Edinburgh Medical School, Scotland, UK) David I. Smith (Mayo Clinic College of Medicine, Rochester, MN, USA) Molecular Anthropology: Pavao Rudan (Institute for Anthropological Research, Zagreb, Croatia) Peter Underhill (Stanford University Medical Center, Stanford, CA, USA) Local Organizing Committee: Šimun Anÿelinoviü Damir Marjanoviü Ivana Erceg Ivkošiü, Chair Petar Projiü Ante Ivkošiü Duje Rako - webmaster Dalibor Marijanoviü Ivana Šamija Projiü Inga Marijanoviü Vedrana Škaro Assistance to the Local Organizing Committee: Šime Brkiü Ivan Mateljak Katarina Caput Mihaliü Igor Matiü Mateja Hajdinjak Marija Mazor Martina Kralj Zrinka Romiü Ivana Kutle Jerko Štambuk Josip Maduniü Ante Vuliü Mija Marinkoviü Official service agency of the conference: VenEvent Gunduliüeva 3, 10000 Zagreb, Croatia www.venevent.com tel ++385 (1) 55 083 04 fax ++385 (1)48 200 49 [email protected] www.venevent.com ID Code: HR-A-01-080443208 7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine 6 June 20-24, 2011, Bol, Island of Braþ, Croatia ISABS Committees ISABS Committees ISABS registration number: 21003655 Date of registration: August 27, 2004 President: Ivana Erceg-Ivkošiü (Clinical Hospital "Sveti Duh", Zagreb, Croatia) Vice President: Inga Marijanoviü (University of Zagreb, Faculty of Science, Zagreb, Croatia) General Secretary: Vedrana Škaro (Genos, Forensic DNA Laboratory, Zagreb, Croatia) ISABS Conferences Founding Members: Dragan Primorac (University of Split and University of Osijek, Croatia; The Pennsylvania State University and University of New Haven, USA) Moses Schanfield (George Washington University, Washington, DC, USA) Stanimir Vuk-Pavloviü (Mayo Clinic College of Medicine, Rochester, MN, USA) Scientific Committee: Forensic Genetics: Antonio Alonso (National Institute of Toxicology and Forensic Sciences, Madrid, Spain) Chris Asplen (Gordon Thomas Honeywell Governmental Affairs, Washington, DC and DNA 4 Africa, Chalfont, Pennsylvania, USA) Zoran Budimlija (Office of Chief Medical Examiner, New York, NY, USA) Cecelia Crouse (Palm Beach Sheriff's Office, West Palm Beach, FL, USA) Jürgen Henke (Institut für Blutgruppenforschung, Köln, Germany) Mitchell Holland (The Pennsylvania State University, USA) Henry Lee (University of New Haven, West Haven and Connecticut Forensic Science Laboratory, Meriden, CT, USA) José Antonio Lorente (Pfizer - University of Granada & Andalusian Government Centre for Genomics & Oncology, Granada, Spain) Marilyn Menotti-Raymond (National Cancer Institute, Frederick, MD, USA) Antti Sajantila (Department of Forensic Medicine, University of Helsinki, Helsinki, Finland) Molecular and Cellular Medicine: Henry Erlich (Roche Molecular Systems, Inc., Alameda, CA, USA) Francis Glorieux (Genetics Unit, Shriners Hospital for Children and McGill University, Montreal, QC, Canada) Robert Huber - Nobel Laureate 1988 (Max Planck Institute for Biochemistry, Martinsried, Germany) Doron Lancet (Weizmann Institute of Science, Rehovot,
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