Anti-SRA1 Monoclonal Antibody, Clone FQS22887 (DCABH-7728) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-SRA1 monoclonal antibody, clone FQS22887 (DCABH-7728) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to SRA1

Antigen Description Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.

Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SRA1 aa 1-100. The exact sequence is proprietary.Database link: Q9HD15

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human

Clone FQS22887

Purity Protein A purified

Conjugate Unconjugated

Applications ICC/IF, Flow Cyt, IHC-P, WB

Positive Control Human fetal liver and kidney lysates; Human ovarian carcinoma tissue; 293 and MCF7 cells.

Format Liquid

Size 100 μl

Buffer pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol, 0.05% BSA

Preservative 0.01% Sodium Azide

Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name SRA1 steroid receptor RNA activator 1 [ Homo sapiens ]

Official Symbol SRA1

Synonyms SRA1; steroid receptor RNA activator 1; steriod receptor RNA activator 1; SRA; STRAA1; steroid receptor coactivator; steroid receptor RNA activator protein; steroid receptor RNA activator 1 (complexes with NCOA1); SRAP; pp7684; MGC87674;

Entrez Gene ID 10011

Protein Refseq NP_001030312

UniProt ID Q9HD15

Chromosome Location 5q31

Function DNA binding; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; receptor activity; thyroid hormone receptor activator activity; transcription coactivator activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]