Anti-SRA1 monoclonal antibody, clone FQS22887 (DCABH-7728) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Rabbit monoclonal to SRA1 Antigen Description Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis. Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SRA1 aa 1-100. The exact sequence is proprietary.Database link: Q9HD15 Isotype IgG Source/Host Rabbit Species Reactivity Mouse, Rat, Human Clone FQS22887 Purity Protein A purified Conjugate Unconjugated Applications ICC/IF, Flow Cyt, IHC-P, WB Positive Control Human fetal liver and kidney lysates; Human ovarian carcinoma tissue; 293 and MCF7 cells. Format Liquid Size 100 μl Buffer pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol, 0.05% BSA Preservative 0.01% Sodium Azide Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Ship Shipped at 4°C. 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved GENE INFORMATION Gene Name SRA1 steroid receptor RNA activator 1 [ Homo sapiens ] Official Symbol SRA1 Synonyms SRA1; steroid receptor RNA activator 1; steriod receptor RNA activator 1; SRA; STRAA1; steroid receptor coactivator; steroid receptor RNA activator protein; steroid receptor RNA activator 1 (complexes with NCOA1); SRAP; pp7684; MGC87674; Entrez Gene ID 10011 Protein Refseq NP_001030312 UniProt ID Q9HD15 Chromosome Location 5q31 Function DNA binding; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; receptor activity; thyroid hormone receptor activator activity; transcription coactivator activity; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.