CBX3 Monoclonal Antibody, Clone ACGB-3

CBX3 monoclonal antibody, clone Entrez GeneID: 11335

ACGB-3 Gene Symbol: CBX3

Catalog Number: MAB22120 Gene Alias: HECH, HP1-GAMMA, HP1Hs-gamma

Regulatory Status: For research use only (RUO) Gene Summary: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner Product Description: Rabbit monoclonal antibody nuclear membrane. The protein encoded by this gene raised against synthetic peptide of human CBX3. binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral Clone Name: ACGB-3 membrane protein found in the inner nuclear membrane. Immunogen: A synthetic peptide corresponding to The dual binding functions of the encoded protein may human CBX3. explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the Host: Rabbit same protein but differing in the 5' UTR, have been found for this gene. [provided by RefSeq] Reactivity: Human,Mouse

Applications: Flow Cyt, IHC, IP, WB-Ce (See our web site product page for detailed applications information)

Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols

Specificity: The antibody reacts with human, mouse CBX3, in native form and recombinant. Superfamily members of CBX3 are not reactive to this antibody.

Form: Liquid

Purification: Affinity purification

Isotype: IgG

Recommend Usage: Flow Cytometry (1:100) Immunohistochemistry (1:50-1:200) Immunoprecipitation (1:50) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.

Storage Buffer: In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).

Storage Instruction: Store at 4°C for short term storage. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.

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