Computation of Delayed Fission Product Gamma Ray Dose Rates from NCSU PULSTAR Reactor Using a Monte Carlo Number Albedo Approach
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Radiation and Risk: Expert Perspectives Radiation and Risk: Expert Perspectives SP001-1
Radiation and Risk: Expert Perspectives Radiation and Risk: Expert Perspectives SP001-1 Published by Health Physics Society 1313 Dolley Madison Blvd. Suite 402 McLean, VA 22101 Disclaimer Statements and opinions expressed in publications of the Health Physics Society or in presentations given during its regular meetings are those of the author(s) and do not necessarily reflect the official position of the Health Physics Society, the editors, or the organizations with which the authors are affiliated. The editor(s), publisher, and Society disclaim any responsibility or liability for such material and do not guarantee, warrant, or endorse any product or service mentioned. Official positions of the Society are established only by its Board of Directors. Copyright © 2017 by the Health Physics Society All rights reserved. No part of this publication may be reproduced or distributed in any form, in an electronic retrieval system or otherwise, without prior written permission of the publisher. Printed in the United States of America SP001-1, revised 2017 Radiation and Risk: Expert Perspectives Table of Contents Foreword……………………………………………………………………………………………………………... 2 A Primer on Ionizing Radiation……………………………………………………………………………... 6 Growing Importance of Nuclear Technology in Medicine……………………………………….. 16 Distinguishing Risk: Use and Overuse of Radiation in Medicine………………………………. 22 Nuclear Energy: The Environmental Context…………………………………………………………. 27 Nuclear Power in the United States: Safety, Emergency Response Planning, and Continuous Learning…………………………………………………………………………………………….. 33 Radiation Risk: Used Nuclear Fuel and Radioactive Waste Disposal………………………... 42 Radiation Risk: Communicating to the Public………………………………………………………… 45 After Fukushima: Implications for Public Policy and Communications……………………. 51 Appendix 1: Radiation Units and Measurements……………………………………………………. 57 Appendix 2: Half-Life of Some Radionuclides…………………………………………………………. 58 Bernard L. -
Nuclear Fusion Enhances Cancer Cell Killing Efficacy in a Protontherapy Model
Nuclear fusion enhances cancer cell killing efficacy in a protontherapy model GAP Cirrone*, L Manti, D Margarone, L Giuffrida, A. Picciotto, G. Cuttone, G. Korn, V. Marchese, G. Milluzzo, G. Petringa, F. Perozziello, F. Romano, V. Scuderi * Corresponding author Abstract Protontherapy is hadrontherapy’s fastest-growing modality and a pillar in the battle against cancer. Hadrontherapy’s superiority lies in its inverted depth-dose profile, hence tumour-confined irradiation. Protons, however, lack distinct radiobiological advantages over photons or electrons. Higher LET (Linear Energy Transfer) 12C-ions can overcome cancer radioresistance: DNA lesion complexity increases with LET, resulting in efficient cell killing, i.e. higher Relative Biological Effectiveness (RBE). However, economic and radiobiological issues hamper 12C-ion clinical amenability. Thus, enhancing proton RBE is desirable. To this end, we exploited the p + 11Bà3a reaction to generate high-LET alpha particles with a clinical proton beam. To maximize the reaction rate, we used sodium borocaptate (BSH) with natural boron content. Boron-Neutron Capture Therapy (BNCT) uses 10B-enriched BSH for neutron irradiation-triggered alpha-particles. We recorded significantly increased cellular lethality and chromosome aberration complexity. A strategy combining protontherapy’s ballistic precision with the higher RBE promised by BNCT and 12C-ion therapy is thus demonstrated. 1 The urgent need for radical radiotherapy research to achieve improved tumour control in the context of reducing the risk of normal tissue toxicity and late-occurring sequelae, has driven the fast- growing development of cancer treatment by accelerated beams of charged particles (hadrontherapy) in recent decades (1). This appears to be particularly true for protontherapy, which has emerged as the most-rapidly expanding hadrontherapy approach, totalling over 100,000 patients treated thus far worldwide (2). -
Radiation and Your Patient: a Guide for Medical Practitioners
RADIATION AND YOUR PATIENT: A GUIDE FOR MEDICAL PRACTITIONERS A web module produced by Committee 3 of the International Commission on Radiological Protection (ICRP) What is the purpose of this document ? In the past 100 years, diagnostic radiology, nuclear medicine and radiation therapy have evolved from the original crude practices to advanced techniques that form an essential tool for all branches and specialties of medicine. The inherent properties of ionising radiation provide many benefits but also may cause potential harm. In the practice of medicine, there must be a judgement made concerning the benefit/risk ratio. This requires not only knowledge of medicine but also of the radiation risks. This document is designed to provide basic information on radiation mechanisms, the dose from various medical radiation sources, the magnitude and type of risk, as well as answers to commonly asked questions (e.g radiation and pregnancy). As a matter of ease in reading, the text is in a question and answer format. Interventional cardiologists, radiologists, orthopaedic and vascular surgeons and others, who actually operate medical x-ray equipment or use radiation sources, should possess more information on proper technique and dose management than is contained here. However, this text may provide a useful starting point. The most common ionising radiations used in medicine are X, gamma, beta rays and electrons. Ionising radiation is only one part of the electromagnetic spectrum. There are numerous other radiations (e.g. visible light, infrared waves, high frequency and radiofrequency electromagnetic waves) that do not posses the ability to ionize atoms of the absorbing matter. -
Literature Survey on Decorporation of Radionuclides from the Human Body
Literature Survey on Decorporation of Radionuclides from the Human Body E.A. Waller, R.Z. Stodilka, K. Leach and L. Prud’homme-Lalonde Defence R&D Canada - Ottawa TECHNICAL MEMORANDUM DRDC Ottawa TM 2002-042 April 2002 Literature Survey on Decorporation of Radionuclides from the Human Body E.A. Waller SAIC Canada, Inc R.Z. Stodilka, K. Leach and L. Prud’homme-Lalonde Space Systems and Technology Defence R&D Canada - Ottawa Technical Memorandum DRDC Ottawa TM 2002-042 April 2002 © Her Majesty the Queen as represented by the Minister of National Defence, 2002 © Sa majesté la reine, représentée par le ministre de la Défense nationale, 2002 Abstract The broad use of radionuclides by many industries has greatly increased the probability of events that could lead to internalized contamination. Examples include accidents and/or intentional damage to nuclear power plants or radiation therapy units in hospitals, the use of radiological dispersal weapons, and lost or stolen radionuclide sources. Developing effective countermeasures requires knowledge of the physical and chemical composition of the radionuclides, their metabolic activities within the body, and methods to expedite their elimination from the body. This report presents a summary of information pertaining to intake and decorporation of radionuclides from humans. This information would be the first step in establishing a field protocol to guide physicians in military missions. Developing such a guide requires an understanding of the dangers associated with internal radioisotope contamination, decision levels for administering therapy (risk vs. benefit) and protocols for administering therapy. As presented, this study could be used to decide what decorporation pharmaceuticals should be maintained in quantity by the military, and how to best train officers with medical responsibilities. -
And Stereotactic Body Radiation Therapy (SBRT)
Geisinger Health Plan Policies and Procedure Manual Policy: MP084 Section: Medical Benefit Policy Subject: Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy I. Policy: Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiation Therapy (SBRT) II. Purpose/Objective: To provide a policy of coverage regarding Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiation Therapy (SBRT) III. Responsibility: A. Medical Directors B. Medical Management IV. Required Definitions 1. Attachment – a supporting document that is developed and maintained by the policy writer or department requiring/authoring the policy. 2. Exhibit – a supporting document developed and maintained in a department other than the department requiring/authoring the policy. 3. Devised – the date the policy was implemented. 4. Revised – the date of every revision to the policy, including typographical and grammatical changes. 5. Reviewed – the date documenting the annual review if the policy has no revisions necessary. V. Additional Definitions Medical Necessity or Medically Necessary means Covered Services rendered by a Health Care Provider that the Plan determines are: a. appropriate for the symptoms and diagnosis or treatment of the Member's condition, illness, disease or injury; b. provided for the diagnosis, and the direct care and treatment of the Member's condition, illness disease or injury; c. in accordance with current standards of good medical treatment practiced by the general medical community. d. not primarily for the convenience of the Member, or the Member's Health Care Provider; and e. the most appropriate source or level of service that can safely be provided to the Member. When applied to hospitalization, this further means that the Member requires acute care as an inpatient due to the nature of the services rendered or the Member's condition, and the Member cannot receive safe or adequate care as an outpatient. -
New Discoveries in Radiation Science
cancers Editorial New Discoveries in Radiation Science Géza Sáfrány 1,*, Katalin Lumniczky 1 and Lorenzo Manti 2 1 Department Radiobiology and Radiohygiene, National Public Health Center, 1221 Budapest, Hungary; [email protected] 2 Department of Physics, University of Naples Federico II, 80126 Naples, Italy; [email protected] * Correspondence: [email protected]; Tel.: +36-309199218 This series of 16 articles (8 original articles and 8 reviews) was written by internation- ally recognized scientists attending the 44th Congress of the European Radiation Research Society (Pécs, Hungary). Ionizing radiation is an interesting agent because it is used to cure cancers and can also induce cancer. The effects of ionizing radiation at the organism level depend on the response of the cells. When radiation hits a cell, it might damage any cellular organelles and macromolecules. Unrepairable damage leads to cell death, while misrepaired alterations leave mutations in surviving cells. If the repair is errorless, normal cells will survive. However, in a small percentage of the seemingly healthy cells the number of spontaneous mutations will increase, which is a sign of radiation-induced genomic instability. Radiation-induced cell death is behind the development of acute radiation syndromes and the killing of tumorous and normal cells during radiation therapy. Radiation-induced mutations in surviving cells might lead to the induction of tumors. According to the central paradigm of radiation biology, the genetic material, that is the DNA, is the main cellular target of ionizing radiation. Many different types of damage are induced by radiation in the DNA, but the most deleterious effects arise from double strand breaks (DSBs). -
Radiation Therapy
Radiation Therapy What is radiation therapy? Radiation therapy is the use of high-energy x-rays or other particles to destroy cancer cells. A doctor who uses radiation therapy to treat cancer is called a radiation oncologist. The goal of radiation therapy is to destroy the cancer cells without harming nearby healthy tissue. It may be used along with other cancer treatments or as the main treatment. Sometimes radiation therapy is used to relieve symptoms, called palliative radiation therapy. More than half of all people with cancer receive some type of radiation therapy. What are the different types of radiation therapy? The most common type is called external-beam radiation therapy, which is radiation given from a machine located outside the body. Types of external-beam radiation therapy include proton therapy, 3-dimensional conformal radiation therapy (3D-CRT), intensity-modulated radiation therapy (IMRT), and stereotactic radiation therapy. Sometimes radiation therapy involves bringing a radioactive source close to a tumor. This is called internal radiation therapy or brachytherapy. The type you receive depends on many factors. Learn more about radiation treatment at www.cancer.net/radiationtherapy. What should I expect during radiation therapy? Before treatment begins, you will meet with the radiation oncologist to review your medical history and discuss the potential risks and benefits. If you choose to receive radiation therapy, you may undergo tests to plan the treatment and evaluate the results. Before radiation therapy begins, it must be planned carefully. This planning stage is often called a “simulation.” During this visit, the medical team will figure out the best position for you to be in during treatment. -
A Framework for Quality Radiation Oncology Care
Safety is No Accident A FRAMEWORK FOR QUALITY RADIATION ONCOLOGY CARE DEVELOPED AND SPONSORED BY Safety is No Accident A FRAMEWORK FOR QUALITY RADIATION ONCOLOGY CARE DEVELOPED AND SPONSORED BY: American Society for Radiation Oncology (ASTRO) ENDORSED BY: American Association of Medical Dosimetrists (AAMD) American Association of Physicists in Medicine (AAPM) American Board of Radiology (ABR) American Brachytherapy Society (ABS) American College of Radiology (ACR) American Radium Society (ARS) American Society of Radiologic Technologists (ASRT) Society of Chairmen of Academic Radiation Oncology Programs (SCAROP) Society for Radiation Oncology Administrators (SROA) T A R G E T I N G CAN CER CAR E The content in this publication is current as of the publication date. The information and opinions provided in the book are based on current and accessible evidence and consensus in the radiation oncology community. However, no such guide can be all-inclusive, and, especially given the evolving environment in which we practice, the recommendations and information provided in the book are subject to change and are intended to be updated over time. This book is made available to ASTRO and endorsing organization members and to the public for educational and informational purposes only. Any commercial use of this book or any content in this book without the prior written consent of ASTRO is strictly prohibited. The information in the book presents scientific, health and safety information and may, to some extent, reflect ASTRO’s and the endorsing organizations’ understanding of the consensus scientific or medical opinion. ASTRO and the endorsing organizations regard any consideration of the information in the book to be voluntary. -
Internal and External Exposure Exposure Routes 2.1
Exposure Routes Internal and External Exposure Exposure Routes 2.1 External exposure Internal exposure Body surface From outer space contamination and the sun Inhalation Suspended matters Food and drink consumption From a radiation Lungs generator Radio‐ pharmaceuticals Wound Buildings Ground Radiation coming from outside the body Radiation emitted within the body Radioactive The body is equally exposed to radiation in both cases. materials "Radiation exposure" refers to the situation where the body is in the presence of radiation. There are two types of radiation exposure, "internal exposure" and "external exposure." External exposure means to receive radiation that comes from radioactive materials existing on the ground, suspended in the air, or attached to clothes or the surface of the body (p.25 of Vol. 1, "External Exposure and Skin"). Conversely, internal exposure is caused (i) when a person has a meal and takes in radioactive materials in the food or drink (ingestion); (ii) when a person breathes in radioactive materials in the air (inhalation); (iii) when radioactive materials are absorbed through the skin (percutaneous absorption); (iv) when radioactive materials enter the body from a wound (wound contamination); and (v) when radiopharmaceuticals containing radioactive materials are administered for the purpose of medical treatment. Once radioactive materials enter the body, the body will continue to be exposed to radiation until the radioactive materials are excreted in the urine or feces (biological half-life) or as the radioactivity weakens over time (p.26 of Vol. 1, "Internal Exposure"). The difference between internal exposure and external exposure lies in whether the source that emits radiation is inside or outside the body. -
Chapter 5 TREATMENT MACHINES for EXTERNAL BEAM
Chapter 5 TREATMENT MACHINES FOR EXTERNAL BEAM RADIOTHERAPY E.B. PODGORSAK Department of Medical Physics, McGill University Health Centre, Montreal, Quebec, Canada 5.1. INTRODUCTION Since the inception of radiotherapy soon after the discovery of X rays by Roentgen in 1895, the technology of X ray production has first been aimed towards ever higher photon and electron beam energies and intensities, and more recently towards computerization and intensity modulated beam delivery. During the first 50 years of radiotherapy the technological progress was relatively slow and mainly based on X ray tubes, van de Graaff generators and betatrons. The invention of the 60Co teletherapy unit by H.E. Johns in Canada in the early 1950s provided a tremendous boost in the quest for higher photon energies and placed the cobalt unit at the forefront of radiotherapy for a number of years. The concurrently developed medical linacs, however, soon eclipsed cobalt units, moved through five increasingly sophisticated generations and became the most widely used radiation source in modern radiotherapy. With its compact and efficient design, the linac offers excellent versatility for use in radiotherapy through isocentric mounting and provides either electron or megavoltage X ray therapy with a wide range of energies. In addition to linacs, electron and X ray radiotherapy is also carried out with other types of accelerator, such as betatrons and microtrons. More exotic particles, such as protons, neutrons, heavy ions and negative p mesons, all produced by special accelerators, are also sometimes used for radiotherapy; however, most contemporary radiotherapy is carried out with linacs or teletherapy cobalt units. -
This File Was Downloaded From
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Queensland University of Technology ePrints Archive This is the author’s version of a work that was submitted/accepted for pub- lication in the following source: Poole, Christopher, Trapp, Jamie, Kenny, John, Kairn, Tanya, Williams, Kerry, Taylor, Michael, Franich, Rick, & Langton, Christian M. (2011) A hybrid radiation detector for simultaneous spatial and temporal dosimetry. Australasian Physical and Engineering Sciences in Medicine, 34(3), pp. 327-332. This file was downloaded from: http://eprints.qut.edu.au/42062/ c Copyright 2011 Australasian College of Physical Scientists and Engineers in Medicine Notice: Changes introduced as a result of publishing processes such as copy-editing and formatting may not be reflected in this document. For a definitive version of this work, please refer to the published source: http://dx.doi.org/10.1007/s13246-011-0081-5 A hybrid radiation detector for simultaneous spatial and temporal dosimetry C. Poole1 , J.V. Trapp1*, J. Kenny2 ,T. Kairn2 , K. Williams3, M. Taylor3, R. Franich3, C.M. Langton1 1. Physics, Faculty of Science and Technology, Queensland University of Technology, GPO Box 2434, Brisbane Qld 4001, Australia 2. Premion, The Wesley Medical Centre, Suite 1 40 Chasely Street, Auchenflower Queensland 4066, Australia 3. School of Applied Sciences, RMIT University, GPO Box 2476, Melbourne 3001, Australia *Corresponding Author: Email: [email protected], Phone +61 7 31381386, Fax +61 7 1389079 Keywords: Radiotherapy, Dosimetry, Gel Dosimetry, Radiation Measurement, 4D dosimetry 1 Abstract In this feasibility study an organic plastic scintillator is calibrated against ionisation chamber measurements and then embedded in a polymer gel dosimeter to obtain a quasi-4D experimental measurement of a radiation field. -
Medical Sources of Radiation
Medical Sources of Radiation Professional Training Programs Oak Ridge Associated Universities Objectives To review the most common uses of radiation in medicine. To discuss new uses for radiation in medicine. To review pertinent regulatory issues. 2 Introduction Medical exposure to an average American is about 3 mSv/yrmSv/yr (300 mrem/yr),mrem/yr), or about 48% of the total average exposure of 620 mremmrem.. Medical exposure to radiation is the largest contributor to our annual average exposure from manman--mademade sources. 3 NCRP Report 160 4 Introduction People are intentionally and purposefully irradiated during medical radiological procedures, which is something that is usually avoided in all other applications using radiation. 5 Introduction The goal in medicine is to minimize risk (keep doses low), without compromising the benefit of the procedure (diagnosis or treatment). 6 Introduction Radiation dose to patients is not regulated. Radiation doses per procedure are decreasing (with a few exceptions), but more procedures are being performed. 7 Introduction There are traditionally three branches of medicine that use ionizing radiation. – Diagnostic Imaging – Nuclear medicine – Radiation therapy 8 Diagnostic Imaging Diagnostic X-X-RayRay Fluoroscopy Mammography Bone Densitometry Computed Tomography Special Procedures Cardiac Cath Lab 9 Diagnostic Imaging MRI and ultrasound procedures do not use ionizing radiation, so will not be discussed. 10 Diagnostic Imaging People who have had xx--rayray procedures or CT scans have been exposed to ionizing radiation, but are not radioactive. 11 Diagnostic Imaging The states regulate the users of x-x-rayray equipment, the FDA regulates the manufacture of x-x-rayray equipment. 12 Diagnostic Imaging 13 Diagnostic Imaging 14 Diagnostic Imaging 15 Diagnostic Imaging 16 Nuclear Medicine The patient is purposefully administered radioactive material, and becomes the source of radiation.