Weissella Cibaria, Lactobacillus Plantarum)
JOURNAL OF CANCER PREVENTION http://dx.doi.org/10.15430/JCP.2014.19.4.253 Vol. 19, No. 4, December, 2014 pISSN 2288-3649ㆍeISSN 2288-3657 Cancer Preventive Potential of Kimchi Lactic Acid Review Bacteria (Weissella cibaria, Lactobacillus plantarum) Shin-Hye Kwak1, Young-Mi Cho1, Geon-Min Noh2, Ae-Son Om1 1Laboratory of Food Safety and Toxicology, Department of Food Science and Nutrition, College of Human Ecology, Hanyang University, Seoul, Korea, 2Functional Food and Nutrition Division, Department of Agrofood Resources, National Academy of Agricultural Science, Wanju, Korea The number of death due to cancer has been increasing in Korea. Chemotherapy is known to cause side effects because it damages not only cancerous cells but healthy cells. Recently, attention has focused on food-derived chemopreventive and anti-tumor agents or formulations with fewer side effects. Kimchi, most popular and widely consumed in Korea, contains high levels of lactic acid bacteria and has been shown to possess chemopreventive effects. This review focuses on Weissella cibaria and Lactobacillus plantarum, the representatives of kimchi lactic acid bacteria, in terms of their abilities to prevent cancer. Further studies are needed to understand the mechanisms by which lactic acid bacteria in kimchi prevent carcinogenic processes and improve immune functions. (J Cancer Prev 2014;19:253-258) Key Words: Kimchi, Weissella cibaria, Lactobacillus plantarum, Anticancer, Lactic acid bacteria INTRODUCTION selectively destroy specific cancer cells. However, because of problems, such as tolerance manifestation, partly critical toxicity, According to the Korean national statistical office, the main decrease in sensitivity, and restriction in subjects, new drugs take cause of death in Korea was cancer in 2012.
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