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INNOVATIVE BIOPROCESS EQUIPMENT 2 SOLIDABIOTECH.Com 3 SOLIDABIOTECH.coM INNOVATIVE BIOPROCESS EQUIPMENT 2 SOLIDABIOTECH.coM 3 Solida Biotech is the ideal bioprocess partner to find the solution that suits your specific needs SOLIDA BIOTECH We are a dynamic company that specialises in engineering, developing, and manufacturing in- novative bioprocess equipment. The company was founded by a management team with over 20 years’ experience in the fields of fermentation, cell culture, sterile processing, software and automation technologies, with the aim of meeting the challenges of producing and supplying leading industrial and institutional customers with a new generation of bioreactors and fermenters for research and production, as well as scientific instruments. THE IDEAL BIOPROCESS partner Thanks to the abilities of our skilled team, we can offer flexible and custom made solutions to deal with multiple requirements in the world of green, red and white biotechnologies. Solida offers a wide range of compact and modular bioreactors and fermenters from 50ml to 50 cubic metre pilot and industrial plants and integrated turn-key solutions. All our equipment meets the standards for worldwide distribution. bioprocess solutions We manufacture a wide range of bioreactors, fermenters, at-line analysers, CIP/SIP systems and process vessels for research, development, and production, suitable for fermentation, cell culture, stem cells, re- newable technologies, algae, biomass, biofuel, hydrolysis and more. coMpact bioreactors LaboratorY SIP Bioreactors A compact laboratory bioreactor solution Modular Laboratory SIP stainless steel in characterised by great performance and ease of situ sterilisable bioreactors, from 1 litre up to 50 use, the perfect way to get started. litre w/v as well as custom fit solutions. Versatile bioconsole for autoclavable Bioreactors from 50mL to 30 litres working volume and Pilot & Industrial SIP Disposable from 250mL to 75 litres w/v. bioreactors SIP stainless steel in situ sterilisable and CIPable MODULAR bioreactors bioreactors, from 20 litres up to 50 cubic metres, LABORATORY Latest generation Modular Bioreactors, developed custom fit and turn-key integrated solutions. with industrial automation to provide greater speed, power and expandability for laboratory, CIP SYsteMS AND Process TANKS BIOREACTORS pilot, and industrial scale up processes. Versatile Cleaning in place systems, sterilization units, modular system for autoclavable Bioreactors sanitary vessels and process vessels. from 50mL to 30 Litres w/v, Disposable from 250mL to 75 liters w/v and in Stainless Steel from 1L to 100 Litres w/v. Disposable SYsteMS Single-use Bioprocess Bags, Bioreactors, Contai- parallel bioreactors ners and Mixing Systems 50 mL to 3,000 L volume. Parallel bioreactor systems for advanced bioprocess control and highly efficient process development. AUTOMATION & SOFTWARE Configurable solutions for microbial, phototrophic, Industrial automation platforms and software mammalian and human cells, stem cell applications, solutions for basic and advanced R&D applicati- and biofuel and biopolymer processes. ons and production. Parallel operation of up to 36 re-usable and single-use bioreactors from 50ml to 75 litre w/v. QualitY & Certifications Photo bioreactors We provide a full set of documentation comply- ing to international standards for GLP and cGMP Laboratory, pilot and open field large scale equipment, DQ, IQ, OQ and PQ protocols. photo-bioreactors. Customisable PBR systems are available in three different configurations: round type, air lift and flat panel. Service & Support We provide worldwide service & support. 6 SOLIDABIOTECH.coM 7 The only utility connections you need to operate the Compact Bioreactor COMpact Bioreactor ALL-IN are electricity and gas supply. FOR CELL CULTURE AND FERMENTATION The Compact Bioreactor supports standard 4 fixed and/or variable peristals pumps, Compact Bioreactors is a line of latest generation 4 flowmeters and/or Massflow controllers, bioreactors that can be used for basic sensors for PH, PO2, Temperature, Level, Foam, educational applications, but also for advanced Biomass, Gas Analyser, Glucose Analyser and more. bioprocessing and development. Powerful mechanical and/or magnetic Applications include cell culture, stem cells, mixing system with variable range from 0 fermentation of bacteria, fungus, yeasts, to 2000 rpm for liquid, semi-solid and solid ™ photo-sensitive organisms such as plants and BIOFLEX bioprocesses. algae and more. SOFTWARE VOLUMES Space Restriction The entire bioreactor system is driven by Autoclavable vessels: 300 mL, 500 mL, 1-2-3- Compact is one of the most compact BIOFLEX™ software, with an intelligent Water jacketed bioreactors 5-7-10-15-20-30 Litres bioreactors on the market, occupying interface that is easily accessible, even from 100ml to 30 litres a truly reduced space of 280x400mm for beginners. Thanks to the intuitive user w/v SUB Disposable vessels: 250 mL, 500 mL, 1-3- WxD to meet the needs of any lab. interface, Bioflex is simple to operate, with 5-7-10-15-20-30-50-75 Litres reduced operator errors and reduced training needs. Bioflex software can be RICH CONNECTIVITY installed on a laptop PC, tablet or smartphone, Another winning element of the Compact stronG points and enables you to monitor and control unit is its industrial connectivity with • Its small dimensions, which take up small your bioreactor at any time: in the laboratory, footprint in the lab PCs and external networks, in addition to modern portable devices such as IPads in the office or even at home. • A Control Unit with the latest generation, and mobile phones via real-time Ethernet powerful and reliable PLC - ’Programmable and USB data communication ports. Logic Controller’ • An HMI-PC digital control interface that AdvantaGES Single wall bioreactors supports the functions of a normal PC with heating blanket and • Simplicity of installation, programming Touch control with a 15.6” wide screen cold finger from 50ml to and maintenance 30 litres w/v • Bioflex TM Software included in the • Accuracy and reliability standard management, supervision, and • Certified for GLP and GMP classified data acquisition package. No additional environments external data recording and data • Integrated temperature compensation processing devices are required • Compact design • HMI-PC with Integrated Data Management FLEXIBILITY and Data Acquisition Software The Compact line allows you to alternate over • IP66 protection class 30 types of autoclavable vessels from 50mL up • SensorFlash® - full-feature functionality to 30L volumes in single and / or double wall with removable memory (Micro SD Card) versions and also Disposable Bioreactors from • Saving of operative data on non-volatile 250ml to 75 w/v. memory Disposable jacketed and single wall bioreactors from 250ml to 75 Litres w/v 8 SOLIDABIOTECH.coM 9 The modular Controller’s key aspects are: Expandability of Advanced MODULAR VOLUMES individual modules for Autoclavable vessels: 300 mL, 500 mL, 1-2-3- managing from 1 to 36 Bioreactor bioreactors in parallel, 5-7-10-15-20-30 Litres Interchangeability of Our advanced modular bioreactor series represents modules, easy testing the latest advancements in automation, software SUB Disposable vessels: 250 mL, 500 mL, 1-3- of modules, simplified and mechanical engineering applied to 5-7-10-15-20-30-50-75 Litres interfaces through the bioprocess industry. Industrial standard which the modules technologies, high-flexibility, modularity, easy communicate with each DECISIVE advantaGES other, minimum waiting upgrades and replacements, guaranteed long- The powerful modular controller allows you to times for replacement term spare part availability and after-sales service interchange different types of autoclavable vessels and/or maintenance. distinguish our modular bioreactors from the from 50 mL to 30 litres, Disposable from 250 mL to competition. 75 litres w/v, and SIP stainless steel from 1 litre to 100 litres w/v. SMART DESIGN The modularity and flexibility of our control unit Each module (controller, gas mixing, pumps, offer you the unique advantage of being able thermo loop) can be upgraded, exchanged and to start with 1 bioreactor that can then be replaced at any time without the need for an upgraded to 2-4-6-12-24 and up to 36 bioreactors expert technician. working online with the same or different vessel size and typology. The communication between the various modules via fieldbus. This industrial measuring technique FEATURES allows the measured values to be provided quickly • BioController module with industry leading PLC and securely to the central controller that automates hardware, ModBus and Ethernet communication the machine. protocols to simplify and accelerate single and parallel bioreactor operations The system also offers great benefits in terms of the reliability of the machine and fast installation. • Enhanched sensors capability integrating Online Biomass and Gas Analyzers, Automated samplers, A modern operating concept with Bioflex HPLC, Mass Spec and others Advanced SCADA Software. • Gas mixing module supports 4-8 or more integrated Each Advanced system features an innovative web massflow controllers per vessel, automated gas server, which not only allows the system status and control strategy for cell culture or fermentation measurement data to be displayed, but the command applications and configuration at the same time as well. • Peristaltic pump module with 4-8 or more fix and The user can also rely on another big advantage: variable programmable
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