Phase III: Cellular Membranes and less accessible matrix detox Objectives y Detox strategies for Phase III y Detox (oral) chelators y Discussion y At home strategies using the various chelators y Handouts: y E-Book y Phase III y Dosing for chlorella and cilantro Phase III: Cellular Membranes and less accessible matrix detox

y Detox deposits in extra cellular connective tissues that are more tightly bound to proteins and binding sites on the cells y Detox heavy metal deposits in extra cellular connective tissues that are fibroses, mineralized (plaques in blood vessels) and inaccessible due to hyper-coagulation; y Cellular membranes: this phase starts the intracellular detox, because as the mercury is stripped away from the outside of the cell the intracellular detox mechanisms can transport more mercury to the outside of the cells Phase III: Cellular Membranes and less accessible matrix detox

y Keep cellular barriers closed, start to open the brain barrier, but do not aggressively detox the brain yet. y Continue drainage and organ/structure rehabilitation (outlined in Phase II) through detoxification, normalizing blood flow and regulation signaling. y Support the therapeutics of chronic infections that may occur y This is the phase to start adding cilantro to your at home strategies. y Start to rebuild the intracellular stores of glutathione

At home: Detox chelators y Chlorella These products are highly considered in Phase III because they penetrate deeper. y Clatherating agents – nano peptides of chlorella and other agents y OSR y Phospho lipids with EDTA y Zeolites Detox chelators Clatherating agents are the nano peptides or the effective binding proteins in chlorella, therefore processed: can be started in phase II y Clatherating agents can be used if chlorella cannot be tolerated y Because clatherating agents are nano particles they are absorbed and more deeply penetrate into the connective tissues. Examples are: y Metal Matrix ,NDF, PCA, Metal Free Dosage: use when taking chlorella or cilantro, 1-2 times a day; Metal Matrix/ Metal Free - 3-10 sprays per dose; others a ¼ to 2 dropper full per dose Detox chelators OSR – oxidative stress relief; usually started in phase III y This very effective oral chelating agent is both fat and water soluble, which gives it enhanced advantage to penetrate into lesser accessible areas of the connective tissues, fatty areas of the body - membranes, nerves and the brain. We often use this agent in Phase III and IV. y OSR is a potent antioxidant and maintains reduced glutathione y One of the most promising agents in our arsenal

Dosages: 50-100 mg 1-2 times a day; one scoop is 50 mg; can be dissolved in Phospho-lipid Exchange for enhanced absorption; use on mobilization and chelation cycles, off on post chelation and rest cycles; chelation cycle – double the dose Detox chelators Essential Phospholipids (EPL) enhanced with EDTA y Phospholipid Exchange: (Biopure) – 1/3 of bottle mixed thoroughly with 6 ox. Of juice, water or milk. 3 times a week; or 1-3 teaspoon/day at bed time during Phase III- IV brain and cellular detox phase. Synergize well with OSR and others y An energized product of combination of microsphere encapsulated Disodium EDTA, essential phospholipids, Alpha Lipoic acid, and Magnesium. Taken orally this product enhances the transport of these detoxification remedies through the intestinal wall barrier, blood/ cell and blood/ brain barrier. This is the only product that reliably crosses the blood brain barrier y This product successfully eliminates the possibility of diarrhea symptoms. There is a slow release of EDTA systemically over 48 hours, greatly decreasing the possibility of kidney overload with heavy metals. Phospholipid Exchange produces ‘true’ plasma soluble ion exchange properties, thereby minimizing beneficial mineral excretion. y Healing benefits: lowers total serum cholesterol, decreases LDL (bad cholesterol, increases HDO (good cholesterol), increases peripheral and brain circulation, decreases reactive platelet aggregation by 60% in patients with angina pectoris, increases fluidity of RBC cell membranes, decreases angina and helps eliminate chest pains attacks, increases exercise tolerance with angina prone patients. It will enhance acetylcholine in the brain. y Detox Max, Lipoflow - identical products y Detox chelators

Rectal suppository chelators: these are excellent for long term at home therapeutic strategies y Detoxamin – calcium disodium EDTA in time-released suppository form y Taken at night, uptake in lower rectum, which by-passes the liver and enters the blood stream throughout the night with slow absorption, providing slow-acting gentle detoxification during sleep y Can be taken with any IV or oral therapy, therefore it works well in combination with other chelators: i.e. Chlorella, cilantro, DMPS, DMSA, Essential Phospholipids- EDTA, glutathione IV, IM, Trans dermal DMPS, and IV EDTA chelation y Detoxamine is a mesodermal chelator, entering the blood stream and primarily acting on the vascular tree and connective tissues. It can be used in the mobilization and /or the chelation phases with chlorella. y EDTA is a potent antioxidant, anti-aging and removes chemical and metal toxins; it supports cardiovascular and bone health, brain and neurological function. y EDTA removes from the kidney, so kidney support is helpful y Detoxamin’s half life is over 8 hours with good penetration into the connective tissue; a slow and gentile chelator that is safe and effective. Big advantage over IV EDTA including higher concentrations into the prostate and uterus and ovary. y The use of Detoxamin and tetracycline (500mg) with enzymes (Lumbokinase, Rechts-Regulat) will treat the biofilms or calcification deposits in the blood vessel, prostate, beasts and joints. y Dosages and strategies: supplied in 375mg (child’s dose), 750mg (original dose), 1000mg and 1500mg;1 suppository every other night for 1-6 months; use multivitamin and minerals during therapy – especially on the off day. More aggressive treatment for some can include the suppository 7 nights a week for 1 and up to 3 months. Maintenance dose is 1 suppository each week – 2 times per month Detox chelators There are other rectal suppositories that can be prescribed with EDTA, DMPS, glutathione, alpha Lipoic acid and DMSA from special compounding pharmacies. y These give the advantage of a gentile chelation at night, with lower controlled dosages of stronger mercury chelators y It is not advised to use any rectal suppository chelator until the bowel program has been in place for at least two months. If the concentration of mercury and other toxins are greater in the bowel that in the blood vessels, the suppositories will diffuse the heavy metals into the body instead of grabbing the toxic metals and delivering them through the liver – bile – feces. y DMSA: 250-500mg suppository y DMPS: 125-250 mg y Glutathione: y Alpha Lipoic acid Detox chelators y Oral DMSA: y There can be very effective combination therapies at home using a combination of the above suppositories with oral DMSA 500mg daily. All chelating agents should be taken together on the chelating day and mineralize the day off, or separate the chelating agents and mineralizing by at least 12 hours. Detox chelators

Drug Oral Chelators: DMSA y Some use DMSA as primary chelator y less aggressive chelator than DMPS with less side-effects y Approved for the chelation of lead y We do not like to use oral DMSA until the bowel has been detoxed for a while (1-2 months). y The 4th principle states that “systemic detoxification is a process of diffusion and dilution while maintaining bodily barriers.” DMSA can easily mobilize mercury and other heavy metals from the bowel, where it in greater concentration to the body where it would be in lesser concentration. y For these reasons, we prefer to use DMSA, which is an important chelator in the arsenal, later in the detox phases, after the bowel has been detoxed. y DMSA can be used for an urine challenge y Strategies for dosing: y Recommended by the Manufacturer: 10mg/kg per day, taken in three divided doses with meals. y Strategies for DMSA are 3 days on and 11 days off in the early phases before the body has been re- mineralization y Later in detox phases (and after the body has been properly mineralized), DMSA is can be used for longer cycles. When using DMSA for more extended periods of times (i.e. 1-4 months), strategies are to take DMSA in AM of PM, once a day and mineralize opposite (Phase III-IV). y Note: do not supplement with minerals and sulfur prior to using any drug chelator. y DMPS is not effective orally and should not be taken in our view. Detox chelators y The Alpha Lipoic Acid (ALA), including the chelating protocol: y ALA is a naturally occurring food substance that is a potent antioxidant and a weak natural chelator. ALA builds and regenerates glutathione levels in cells; a potent free radical scavenger that regenerates other anti oxidants, such as Vitamins C and E, and coenzyme Q10; it is protective for cells against neurotoxicity and hepato- toxicity of other agents; ALA is protective against mycotoxins (mold and fungi); it is a weak chelator and can mobilize mercury but requires other chelators to re-bind the mercury so it does not relocate the mercury in other tissues. Detox chelators: Alpha Lipoic Acid y Low dose: extra cellular anti- oxidant: 25-50mg/d y Middle dose: intracellular anti-oxidant: 50-150mg/d y Chelating dose: maintain blood levels for at least 3 days y ALA max (time released) 2 tabs= 800 mg for 8-12 hours: 1-2 caps 2 times a day Detox chelators: cilantro y Cilantro- use topical and oral in Phase III, IV and maintenance. Cilantro is a very important herb in mobilizing mercury, cadmium, lead and aluminum in both bones and the central nervous system. It is probably the only effective agent in mobilizing mercury stored in the intracellular space, including the nucleus, the cell wall and cell receptors. Because cilantro may mobilizes more toxins than it is able to carry out, cilantro needs a chelating agent – the favorite is chlorella but others are - clatherating agents, OSR, DMPS, DMSA, Zeolites, EDTA to be effective to remove or chelate the toxins out. Cilantro mobilizes heavy metals through the kidney, liver, and excretes mercury from lungs. Cilantro is good mobilizer but if a GI binding agent is not used (like chlorella), the neurotoxins may be reabsorbed in the small intestine. Cilantro causes the gallbladder to dump bile – containing the excreted neurotoxins into the small intestine. y Cilantro improves the effectiveness of anti-viral and antibiotics in patients with mercury and lead toxicity that co-exist with Chlamydia, herpes and CMV Detox chelators: cilantro y Cilantro tinctures are best prepared in hot water, which will evaporate a mild toxin in the tincture and create a more active product. Dosage: y Start with 2-3 drops 1-2 times a day in hot water and build up to full dose of 1-2 dropper full; 30 - 60 minutes after chlorella. y Topical: rub on skin anywhere there are symptoms Support agents for Phase III penetrate the connective tissues that have been fibrosed or hyper coagulation and detox the cellular membranes y Rechts- Regulat y Systemic Enzyme therapy y Carnosine y Oral, Sub-Q, patches - Heparin Support agents: Rechts- Regulat This product is very beneficial and inexpensive. It is much more effective than the enzyme products listed below, as well as heparin. It can have a positive effect on all bodily functionsOral Dosages: y 1-2 times a day on an empty stomach (AM and PM); 1 tablespoon (10ml) taken straight of diluted in water y Topical: make a 1:1 dilution (must be in a glass container) and apply topically to skin or scalp in any affected area

Regulation therapy y Regulation therapy: as outlined in Phase II y Allergy elimination therapeutics, drug up-take, drainage organ support, treating the ANS – acupuncture, neural therapy, energetic modalities (energetic foot baths), Micro-current (KMT), Laser Enhanced Detox (LED), Erchonia laser… The new remedies to consider in this phase to facilitate cellular detox and repair, helping the cells regain normal function are: y Schwef- Heel: Sulfur metabolism, This remedy will increase the yield of mercury and other heavy metals, because is gives normal regulation information to all sulf-hydral (-SH) enzymes; y Thuja forte: Universal vaccine antidote y Thalamus Compositum: Organ extracts of all glands in brain; Cyclic-AMP Regulation therapy Co Enzyme Compositum (also Citrokehl) y Enzymes of the citric acid cycle – increase ATP and aerobic metabolism y Removes the cellular biochemical blocks of the cells after toxins y Increases the activity and amount of peroxisomes – which detox the intracellular spaces. y 2 times / week for the first month, then 1 / week for the entire treatment (2 years) y This can be taken in multiple modes of treatment: y IM, sub-q, intra-cutaneous, intra nasal and or IV y Ubichinon compositum: for metabolic stimulation and cellular chemical detox y Cerebromax – homeopathic dilution principles to balance the brain’s key information drivers, the neurotransmitters, while employing suis brain tissue to focus the effect of those ingredients specific to the brain functions y Spinomax – is designed to focus on all functions and physiology that is the responsibility of the spine to, perform especially the movement and flow of information. y Matrix support – helps with symptoms related to congestion of in interstitial matrix, enabling the proper absorption of key minerals needed for hormone production and passage of key nutrients and byproducts across the matrix into and out of cell membranes Phase III: check list

At this time you should have: y Removed all mercury from mouth, be knowledgeable and reduce exposure to all heavy metals and toxic chemicals in foods, cosmetics, personal care products, home and environment y Been made aware and remediate your home for noxious energies, mold, create a bedroom sanctuary. y Been working on your bowel rehabilitation for many months. Your bowel chronic inflammation is gone or under control, the dys-biosis is under control, the immune system not so hyper-reactive. y You are eating mostly organic foods, drinking pure fortified water with electrolytes y You have had your allergies to heavy metals, foods, supplements, yourself and the environment identified and in the process of being treated y You have been on chlorella and other bowel binders for at least 2-3 months, and other Phase II chelators. Phase III: check list

y You have identified your mineral shortage and been supplementing for at least 2-3 months with a general mineral and the specific minerals (to include selenium) that you need per your RBC Mineral analysis. y You have been eating quality proteins, using digestive enzymes if needed, supplementing with MAP and using SAMe for many months y You have been supplementing with fish oils for many months and your membrane rehabilitation program is well under way. y Have your sulfur metabolism corrected and have been building up your sulfur stores y Have been eating foods high in anti-oxidants and supplementing anti- oxidants y Have had at least one chelation - DMPS with Neural Therapy, where your scars were injected y You have been applying drug-up-take enhancement techniques to direct the detox agents and nutrients to the areas of most need for detox and rehabilitation. You know and practice your tapping points. Phase III: the basics

Antioxidant protection y Foods: y Supplements: Garlic, vitamin C complex, Vitamin E complex, Alpha Lipoic Acid, Co Q- 10 y Super foods and herbs; Ecklonia cava, Resveratrol, Juice Plus, Wild Blueberry, golgi, Mona vie (acai), green tea, plant phenols Minerals/ electrolytes: y Foods: organic, whole, raw, blending, juicing y Supplements: general; specific – selenium, magnesium, potassium, others y Drinking water with electrolytes Sulfur: y Foods: cruciferous vegetables, garlic, chlorella, eggs y Supplements: MSM, NAC, Oncoplex Phase III: the basics Proteins: y Foods: quality proteins, organic if possible, eggs y Supplements: MAP, SAMe Essential fatty acids (membrane rehabilitation) y Foods: fish, butter, good fats and oils, chlorella y Supplements: fish oils, lecithin, phospho-lipid, Ca Butyrate GI support: y Replace – digestive enzymes y Remove – allergic foods, inflammation from heavy metals (chlorella, IMD, green clay…), dys-biotic bugs (garlic, other programs) y Restore – healthy flora y Repair – IgG2000, Zn Carnosine, GlutAloeMine, MAP, Vitamin D Methylation: B-12, folate, SAMe, Betaine HCl Organ drainage: lymph, liver, kidney Detox strategies for Phase III:

Deeper into the connective tissues, break up the coagulopathy, fibrosis; detox the cell membranes; start to open the brain, start to rehab the cellular detox and function. At Home Chelators: y Chlorella and cilantro y Nano-chlorella (Metal matrix, NDF, Metal Free) y OSR y Phospo-Lipid exchange (DetoxMax) y Zeolite y Suppository: Detoxamin (EDTA), DMSA, DMPS y Oral chelator: DMSA y Alpha Lipoic Acid y Rebuild intracellular glutathione: whey protein, Alpha lipoic acid, freeze dried garlic, NAC, Max GSL y Detox strategies for Phase III:

Support, matrix penetration: y Rechts-Regulat y Systemic enzyme therapy y Heparin: oral, patch, subQ y Carnosine Detox strategies for Phase III:

Support Other y Organ drainage y Hormonal, metabolic y Psycho-emotional, belief systems, stress y Exercise program y Stress program y Chronic infections Regulation support y Schwef-Heel, Co-enzyme Compositum, Ubichinon, Thuja forte, Thalamus Compositum, Cerebromax, Spinalmax, Matrix support