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Shaffer CV 010419.Pdf CURRICULUM VITAE Name: Thomas H. Shaffer, MS.E., Ph.D. Office Address: Temple University School of Medicine Department of Physiology 3420 North Broad Street Philadelphia, PA 19140 Office Address: Nemours Research Lung Center Department of Biomedical Research Alfred I. duPont Hospital for Children 1600 Rockland Road, A/R 302 Wilmington, DE 19803 Present Academic and Hospital Appointments: 2004 – Present Director, Nemours Center for Pediatric Research Nemours Biomedical Research Alfred I duPont Hospital for Children 1600 Rockland Road Wilmington, DE 19803 2001 - Present Associate Director , Nemours Biomedical Research Nemours Children’s Clinic – Wilmington of The Nemours Foundation Alfred I. duPont Hospital for Children, Wilmington, DE 19803 Director, Nemours Pediatric Lung Center Nemours Children's Clinic - Wilmington of The Nemours Foundation Alfred I. duPont Hospital for Children, Wilmington, DE Director, Office of Technology Transfer Nemours Children's Clinic - Wilmington of The Nemours Foundation Alfred I. duPont Hospital for Children, Wilmington, DE Professor, Pediatrics, Department of Pediatrics Thomas Jefferson University, College of Medicine, Philadelphia, PA 2001-Present Professor Emeritus, Physiology and Pediatrics, Departments of Physiology and Pediatrics Temple University School of Medicine, Philadelphia, PA 1 Training, Awards, Societies, and Membership: Education: 1963-1968 B.S. Mechanical Engineering, Drexel University, Philadelphia, PA 1968 Mathematics, Pennsylvania State University, State College, PA 1969-1970 MSE. Applied Mechanics, Drexel University, Philadelphia, PA 1970-1972 Ph.D., Applied Mechanics, Drexel University, Philadelphia, PA Advisor: Dr. Gordon D. Moskowitz Postgraduate Training: 1972-1974 Postdoctoral Fellow, Department of Physiology, School of Medicine University of Pennsylvania, Philadelphia, PA Advisor: Dr. Arthur B. Dubois Awards, Honors and Membership in Honorary Societies: 1964-1968 Dean's List, Drexel University; Pi Tau Sigma; Olin Matheson Fellowship; Awarded Ford Foundation Fellowship; Tau Beta Pi 1969 Inventors Fulcrum of Progress Award 1974 Scholar of the Pennsylvania Plan; Sigma Xi 2005 Temple University Million Dollar Research Award Club 2010 Who’s Who in America 2010 Nomination for the 2010 National Medal of Technology and Innovation Award Membership in Professional and Scientific Societies: American Association Advancement of Science American Thoracic Society American Physiology Society American Pediatric Society New York Academy of Sciences Laennec Society Philadelphia Neonatal Society Philadelphia Physiology Society Society of Critical Care Medicine Editorial Board: Emeritus Pediatric Pulmonology Emeritus Pulmonary Researcher Emeritus Biology of the Neonate US and European Journal of Paediatrics Journal of Orthopedic Surgery and Techniques Journal Reviewer: Acta Paediatrica American Review of Respiratory Disease American Journal of Respiratory and Critical Care Medicine American Journal of Physiology Anesthesiology Annals of Biomedical Engineering Archives of Pediatrics and Adolescent Medicine 2 Biology of the Neonate Critical Care Medicine Journal Reviewer: American Journal of Physiology European Respiratory Journal Journal of Applied Physiology Journal of Pediatrics Journal of Developmental Physiology Journal of Orthopedic Surgery and Techniques IEEE Transaction for Biomedical Engineering Intensive Care Medicine Obstetrics and Gynecology Pediatric Research Pediatric Pulmonology Pediatric Critical Care Medicine Pediatrics Radiation Research Respiratory and Critical Care Medicine 3 Academic Appointments and Experience: Previous Academic Appointments: 1968 Instructor of Mechanical Engineering, Pennsylvania State University, State College, PA 1972-1974 Postdoctoral Fellow in Physiology, Department of Physiology, School of Medicine, University of Pennsylvania, Philadelphia, PA 1974-1975 Research Associate in Physiology, Department of Physiology, School of Medicine, University of Pennsylvania, Philadelphia, PA 1975-1976 Associate in Physiology & Medicine, Departments of Physiology and Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA 1976-1977 Assistant Professor of Physiology, Department of Physiology, School of Medicine, University of Pennsylvania, Philadelphia, PA 1977-1987 Director, Respiratory Physiology Section. Associate Professor of Physiology, Departments of Physiology and Pediatrics, Temple University School of Medicine, Philadelphia, PA 1987-2001 Director, Respiratory Physiology Section. Professor of Physiology, Departments of Physiology and Pediatrics, Temple University School of Medicine, Philadelphia, PA Industrial Experience: 1968-1970 Systems Engineer, Navigation and Control Systems Laboratory, General Electric Co., Valley Forge, PA Consulting Positions: 1970–1972 Systems Consultant, Navigation and Control Systems Laboratory, General Electric Co., Valley Forge, PA 1972–1974 Systems Consultant, AVCO Everett Research Laboratory, Everett, MA. 1975-2000 Pulmonary Consultant, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 1979–1982 Ad Hoc Consultant, National Heart, Lung and Blood Institute, Cardiovascular & Pulmonary Study Section, Bethesda, MD 1980–1985 Pulmonary Consultant, Veterans Administration Medical Center, Philadelphia, PA 1980–1995 Pulmonary Consultant, St. Christopher's Hospital for Children, Temple University, Philadelphia, PA 1981–1989 Pulmonary Consultant, Pennsylvania Hospital, Newborn Pediatrics, Philadelphia, PA 1985–1989 Pulmonary Consultant, Medical Associated Services, Hatfield, PA 1989–1991 Pulmonary Consultant, Biopulmonics, Inc., Redmond, WA 1991–2001 Pulmonary Consultant, Alliance Pharmaceutical Corp., San Diego, CA 1998–2001 Pulmonary Consultant, Mallinckrodt Medical, St Louis, MO 1994–2004 Pulmonary Consultant, Ross Products Division, Columbus, Ohio 1999–2004 Pulmonary Consultant, Hill-Rom, Hatboro, PA 1999–present Intertek Testing, Inc., Chicago, IL 2000–2004 Physiology Consultant, CryoFluor Therapeutics, L.L.C.,Tucson, AZ 2001–2010 Benechill, Inc., San Diego, CA 2002–2004 Research Consultant, BattellePharma, Inc., Columbus, OH 2003–2005 Arizeke Pharmaceuticals, Inc., San Diego, CA 4 Grant Support: Previous Support: “Feasibility Investigation of Laminar Jet Techniques”, Naval Air Systems Command, NOD-19-69-C-0104, 1968-70, Co-Principal Investigator. “Liquid Ventilation in Newborn Lambs with RDS”, NHLBI, HL17154, 1974-76, Principal Investigator. “Pulmonary Physiology in Liquid Ventilation”, NHLBI, HL19402, 1976-78, Principal Investigator. “Pulmonary Physiology in Liquid Ventilation”, BRSG 501-977-699, 1977-78, Principal Investigator. “Pulmonary Physiology in Liquid Ventilation”, NHLBI, HL33843, 1978-83, Principal Investigator. “Pulmonary Training Grant: Experimental Pulmonary Emphysema”, NHLBI, 1978-83, Faculty Member, Preceptor. “Biochemical and morphological changes in fetal and newborn lungs after liquid ventilation”, NIH BRSG- 501-978-78, 1984-85, Principal Investigator. “Pulmonary Training Grant: Experimental Obstructive Lung Diseases”, NHLBI, 1984-89, Faculty Member, Preceptor. “Physiologic Responses to Oxygenation in Early Development”, NHLBI, HL30525, 1984-88, Principal Investigator. “Functional Characteristics of Immature Airways”, NHLBI, HL32031, 1985-88, Principal Investigator. “Small Instrumentation Grant”, NIH BRSG 1515CA46242-01, 1986-87, Principal Investigator. “The Effect of Blood Glucose Levels on CNS Function During Early Development”, American Diabetes Association, 1988-89, Co-Principal Investigator. “Lung Cancer Hyperthermia Via Ultrasound and PFC Liquids”, NIH NCI CA48611, 1988-89, Co-Principal Investigator. “Feasibility Investigation of Multifluor Inert Fluid APF-140 as a Ventilation Medium”. Air Products, 1990-91, Principal Investigator. “Feasibility Investigation of Perfluorooctylbromide fluid as a ventilation medium”. Alliance Pharmaceutical Corp., 1991-92, Principal Investigator. “Comparison of Surfactant-Treated Gas Ventilation and Surfactant-Treated Liquid Ventilated Preterm Lambs”, Chiesi, S.P.A., Parma, Italy, 1991-92, Principal Investigator. “Combined Liquid Ventilation-ECMO Therapy for Respiratory Distress”, Psicor Corp., 1992-93, Principal Investigator. “Lung Cancer Hyperthermia Via Ultrasound and PFC Liquids”, NIH NCI CA48611-(Phase II), 1990-93, Principal Investigator. “Pulmonary Administration of Histamine with Liquid Ventilation: Evaluating Distribution and Pulmonary vs. Systemic Vascular Responses in Newborn Lambs”, Wyeth Pediatrics, 1994-95, Co-Investigator. Grant Support: Previous Support: “Adenosine Receptor Studies in Pulmonary Airways and Vessels in the Developing Lamb”, Merck Laboratories, 1993-95, Principal Investigator. “Enhanced Pulmonary Distribution of Exogenous Surfactant with the use of Liquid Ventilation in Experimental RDS”, Ross Laboratories, 1992-97, Principal Investigator. “Measurement of nitric oxide formation during inhalational nitric oxide therapy”, AHERF- Singer Foundation, 1995-97, Co-Investigator. “A quantitative method for in-vivo assessment of airway compliance”, AHERF- Singer Foundation, 1995-97, Co-Investigator. “Effect of liquid ventilation in the treatment of hydrocarbon pneumonitis”, AHERF- Singer Foundation, 1995-97, Co-Investigator. “Partial Liquid Ventilation with AFO141: A Pilot Safety Efficacy Study in Premature Newborns with Severe Respiratory Distress Syndrome who have failed Conventional Therapy with Exogenous Surfactant”, Alliance Pharm. Corp, 1994-98, Co-Investigator. “Partial Liquid Ventilation (PLV)
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