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Amsterdamprogram2019 022019.Pdf 3D Cell Culture and Analysis Explore new dimensions in 3D cell modeling As we look to the future of innovation, creating more physiologically relevant models through the study of organoids and spheroids is becoming increasingly important. These three-dimensional (3D) models not only mimic cell functions, they also allow for more robust testing of compounds and a more representative analysis. That’s why we’ve compiled a collection of tested products, protocols, and seminal publications to help you accelerate the development of more realistic cellular models. Find out more about culturing and analyzing organoids and spheroids at thermofi sher.com/organoid For Research Use Only. Not for use in diagnostic procedures. © 2018 Thermo Fisher Scientifi c Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientifi c and its subsidiaries unless otherwise specifi ed. COL23163 1218 PG1965-PJT4432-COL23163-3D-CellModeling-SSCR-PrintAd-Global.indd 1 12/20/18 2:25 PM Stem Cells & Organoids in Development & Disease AMSTERDAM NETHERLANDS Welcome Dear Colleagues, On behalf of the International Society for Stem Cell Research (ISSCR), we warmly welcome you to beautiful Amsterdam for the International Symposia, “Stem Cells & Organoids in Development & Disease.” A leader in life science and health technologies, Amsterdam was recently ranked as one of the top academic and biomedical communities in Europe. Amsterdam’s culture of education and innovation makes it the perfect setting for this timely and important meeting. Research using organoids is rapidly advancing the field of stem cell science. Recent work has demonstrated that stem cells retain self-organizing properties in culture, recapitulating in vivo processes and forming organ- like tissues. This remarkable ability of stem cells and organ progenitors to form organoids has the potential to revolutionize regenerative medicine. Organoids can help illuminate organ development, degeneration, and cancer progression, and patient-derived stem cells can be used to model specific disease variances and to test drug responses. Additionally, this technology could potentially be used in the future for cell replacement therapy, which would bypass the issue of immune rejection. We have created a diverse, engaging program that will explore this cutting-edge technology that is pushing the boundaries of stem cell science. During this symposium you will hear from scientists using organoids to model a wide variety of systems, to uncover novel therapeutics, and to repair organs in vivo. The symposium will be bookended by a forum on the policy and ethics of this regenerative medicine and a panel discussion by leaders of the field on the challenges, limitations, and promise of organoids. In addition, the latest tools and technologies will be on display by innovative companies at the Exhibit Hall, a vibrant hub of meeting activities. This International Symposium presents many opportunities to learn about new areas of research and new approaches to stem cell science, expand your network of colleagues and friends, and build new collabora- tions that can help your research progress. We hope this meeting will inspire you with new ideas and foster a broader appreciation of the field and its exciting potential. Thank you for your continued support of the ISSCR, and your important work that is increasing our understanding of development and disease and advancing the field of regenerative medicine. Sincerely, The Amsterdam Organizing Committee Paola Arlotta, Harvard University, USA Eduard Batlle, Institute for Research in Biomedicine, Spain Nissim Benvenisty, The Hebrew University of Jerusalem, Israel Meritxell Huch, University of Cambridge, UK 1 Stem Cells & Organoids in Development & Disease AMSTERDAM NETHERLANDS Meeting Sponors PLATINUM SPONSOR GOLD SPONSOR ABOUT THE ISSCR Mission Statement government regulators on the basic principles of stem cell science and the realistic potential for new medical The mission of the International Society for Stem Cell treatments and cures. Research (ISSCR) is to promote excellence in stem cell science and applications to human health. The leadership of the ISSCR is acutely aware of the responsibility the Society bears to promote the highest scientific and ethical standards, and is dedicated History & Philosophy to integrity in the rigor and quality of the research With about 4,100 members from over 60 countries, the community’s scientific work, the public policy stands it ISSCR is the preeminent transnational, cross-disciplinary takes on stem cell related issues, and the organization’s science-based organization dedicated to stem cell relations with its key constituents and the public. Only research. such an abiding commitment to integrity can ensure Formed in 2002, the Society promotes global collabora- that as the ISSCR grows, it will continue to serve a fair tion among talented and committed stem cell scientists and trusted advocate by both its internal and external and physicians, and plays a catalyzing role in the develop- stakeholders. ment of effective new medical treatments. Contact Us The Society brings together investigators who are en- gaged in both fundamental and applied research. Their The International Society for Stem Cell Resarch investigations include the use of pluripotent stem cells 5215 Old Orchard Road, Suite 270 and stem cells within adult organs and tissues to create Skokie, Illinois 60077, USA applications in specific therapeutic settings. +1-224-592-5700 www.isscr.org The ISSCR represents academia and industry on a broad www.acloserlookatstemcells.org range of issues that affect the well-being of patients www.facebook.com/isscr and their families, and strives to educate the public and www.twitter.com/isscr 2 AMSTERDAM NETHERLANDS Table of Contents GENERAL INFORMATION ................................4-5 Venue Information .......................................... 4 Registration Information ..................................... 4 Internet Access ............................................. 4 Special Events .............................................. 4 Exhibits Information ......................................... 5 Poster Set-Up and Take-Down ................................ 5 Recording Policy ............................................ 5 ISSCR Policies. 5 BOARD OF DIRECTORS, ORGANIZERS, AND REVIEWERS. 6-7 PROGRAM SCHEDULE . .8-14 Wednesday, 20 February ...................................8-10 Thursday, 21 February ....................................11-12 Friday, 22 February .......................................13-14 SPONSORS AND EXHIBITORS .....................17-19 SPEAKER ABSTRACTS ..............................20-30 Wednesday, 20 February ..................................20-23 Thursday, 21 February ....................................23-28 Friday, 22 February .......................................28-30 POSTER ABSTRACTS .............................31-106 AUTHOR INDEX ....................................107-108 3 Stem Cells & Organoids in Development & Disease AMSTERDAM NETHERLANDS General Information VENUE SPECIAL EVENTS Stem Cells & Organoids in Development & Disease, an Poster Presentations ISSCR 2019 International Symposium, takes place at the Poster presenters will be at their posters for discussion at K.I.T. Royal Tropical Institute, Mauritskade 64, 1092 AD these times: Amsterdam, Netherlands. Odd numbered posters presented Thursday, 21 February Program sessions will take place in the Queen Máxima Hall from 13:00 to 14:00 (Auditorium) of the K.I.T. Royal Tropical Institiute. Even numbered posters presented Friday, 22 February from Registration and coat check can be found by the entrance 13:00 to 14:00 of the K.I.T. Royal Tropical Institute. Refreshment breaks, lunches, poster sessions, reception, and the Exhibit Hall Refreshment Breaks are located in the foyer spaces of the venue. Refreshment breaks will be available in the Marble Hall (Auditorium Foyer) of the venue. Complimentary coffee and tea will be served during the following days and times REGISTRATION AND (times are subject to change): BADGE PICKUP Wednesday, 20 February 15:30 – 16:00 Thursday, 21 February 08:30 – 09:00 Pick up your attendee name badge at the ISSCR Registration 10:30 – 11:00 Desk found by the entrance of the K.I.T. Royal Tropical 15:30 – 16:00 Institute. Friday, 22 February 08:30 – 09:00 Name badges are required for admission to all sessions, 10:30 – 11:00 poster presentations, and social events. Since the meeting Lunch Hours badge serves as proof of participation, all attendees, speakers, and exhibitors are required to wear their badges Thursday, 21 February 12:00 – 14:00 at all times. Access to events may be refused if the meeting Friday, 22 February 12:30 – 14:00 badge is not displayed. Welcome Reception Registration Desk and Badge Pickup Hours Sponsored by Thermo Fisher Scientific Wednesday, 20 February 11:30 – 17:00 The Welcome Reception will take place at Pompstation, Zeeburgerdijk 52, 1094 AE, Thursday, 21 February 08:30 – 17:00 Amsterdam, Netherlands. Friday, 22 February 08:30 – 16:00 Wednesday, 20 February 17:30 – 20:00 Networking Reception INTERNET ACCESS A networking reception will take place at the K.I.T. Royal Complimentary access to the internet is available within the Tropical Institute, in the Marble Hall (Auditorium Foyer). K.I.T. Royal Tropical Institute during the International Thursday, 21 February 17:00 – 18:30 Symposium. Network name: Conference & Events Password: welcometokit As a courtesy to speakers, please be sure
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