Carcinogens CAS DOT SHHC Sources Number Chemical Name

Total Page:16

File Type:pdf, Size:1020Kb

Carcinogens CAS DOT SHHC Sources Number Chemical Name 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 3140 # ACEPHATE 30560-19-1 2783 CA 3 6 8 17 18 PHOSPHORAMIDOTHIOIC ACID, ACETYL-, O,S-DIMETHYL ESTER 0001 # ACETALDEHYDE 75-07-0 1089 CA MU TE F4 1 2 3 4 5 6 7 8 R2 15 17 18 20 21 ACETALDEHYDE 22 2890 # ACETAMIDE 60-35-5 3077 CA 3 6 7 17 18 20 ACETAMIDE 0010 # 2-ACETYLAMINOFLUORENE 53-96-3 CA MU 1 4 5 6 18 20 21 ACETAMIDE, N-9H-FLUOREN-2-YL- 0022 # ACRYLAMIDE 79-06-1 2074 CA R2 1 2 3 4 5 6 7 8 15 17 18 19 20 2-PROPENAMIDE 21 0024 # ACRYLONITRILE 107-13-1 1093 CA TE F3 R2 1 2 3 4 5 6 7 8 14 15 17 18 19 2-PROPENENITRILE 20 21 22 3142 # AF- 2 3688-53-7 CA 7 2-FURANACETAMIDE, .alpha.-[(5-NITRO-2-FURANYL)METHYLENE]- 0029 # AFLATOXINS 1402-68-2 CA MU TE 5 7 AFLATOXINS 0033 # ALDRIN 309-00-2 2761 CA TE 1 2 3 4 6 7 8 14 17 18 19 20 21 1,4:5,8-DIMETHANONAPHTHALENE, 1,2,3,4,10,10-HEXACHLORO-1,4,4a,5,8,8aHEXAHYDRO(1R,4S,4aS,5S,8R,8aR)-rel- Page 1 of 55 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 0039 # ALLYL CHLORIDE 107-05-1 1100 CA F3 1 2 3 4 6 7 8 15 17 18 20 1-PROPENE, 3-CHLORO- 0069 # 2-AMINOANTHRAQUINONE 117-79-3 CA MU 5 6 7 18 9,10-ANTHRACENEDIONE, 2-AMINO- 4012 # 1-AMINO-2,4-DIBROMOANTHRAQUINONE 81-49-2 CA 5 9,10-ANTHRACENEDIONE, 1-AMINO-2,4-DIBROMO- 0072 # 4-AMINODIPHENYL 92-67-1 CA MU 1 2 4 5 6 7 18 20 [1,1'-BIPHENYL]-4-AMINE 0076 # 1-AMINO-2-METHYLANTHRAQUINONE 82-28-0 CA 5 6 7 18 9,10-ANTHRACENEDIONE, 1-AMINO-2-METHYL- 3154 # 2-AMINO-5-(5-NITRO-2-FURYL)-1,3,4-THIADIAZOLE 712-68-5 CA 7 1,3,4-THIADIAZOL-2-AMINE, 5-(5-NITRO-2-FURANYL)- 0083 # AMITROLE 61-82-5 2588 CA 2 3 4 5 6 7 8 14 17 18 20 21 1H-1,2,4-TRIAZOL-3-AMINE 0086 # AMMONIUM ARSENATE 7784-44-3 1546 CA 1 2 3 4 5 6 8 17 18 20 ARSENIC ACID (H3AsO4), DIAMMONIUM SALT 0095 # AMMONIUM CHROMATE 7788-98-9 3077 CA 1 2 3 4 5 6 7 8 17 18 20 CHROMIC ACID (H2CrO4), DIAMMONIUM SALT Page 2 of 55 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 0097 # AMMONIUM DICHROMATE 7789-09-5 1439 CA MU 1 2 3 4 5 6 7 8 15 17 18 20 CHROMIC ACID (H2Cr2O7), DIAMMONIUM SALT 0135 # ANILINE 62-53-3 1547 CA 1 2 3 4 6 7 8 15 17 18 19 20 21 BENZENAMINE 1421 # o-ANISIDINE 90-04-0 2431 CA 1 2 3 4 6 7 8 15 17 18 20 BENZENAMINE, 2-METHOXY- 1422 # o-ANISIDINE HYDROCHLORIDE 134-29-2 CA 5 6 7 18 BENZENAMINE, 2-METHOXY-, HYDROCHLORIDE 0149 # ANTIMONY TRIOXIDE 1309-64-4 3077 CA 1 2 3 4 6 7 8 17 18 20 ANTIMONY OXIDE (Sb2O3) 3167 # APOLLO 74115-24-5 CA 8 1,2,4,5-TETRAZINE, 3,6-BIS(2-CHLOROPHENYL)- 0150 # ARAMITE 140-57-8 CA 7 8 SULFUROUS ACID, 2-CHLOROETHYL 2- [4-(1,1-DIMETHYLETHYL)PHENOXY] -1-METHYLETHYL ESTER 4109 # ARSANILIC ACID 98-50-0 3082 CA 1 2 3 4 5 6 7 8 17 18 20 ARSONIC ACID, (4-AMINOPHENYL)- 0152 # ARSENIC 7440-38-2 1558 CA TE 1 2 3 4 5 6 7 8 17 18 20 ARSENIC Page 3 of 55 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 0153 # ARSENIC ACID 7778-39-4 1554 CA 1 2 3 4 5 6 8 17 18 20 21 ARSENIC ACID (H3AsO4) 0154 # ARSENIC BROMIDE 7784-33-0 1555 CA 1 2 3 4 5 6 8 17 18 20 ARSENOUS TRIBROMIDE 0156 # ARSENIC DISULFIDE 56320-22-0 1557 CA TE 1 2 3 4 5 6 7 8 14 17 18 20 ARSENIC SULFIDE 0157 # ARSENIC IODIDE 7784-45-4 1557 CA 1 2 3 4 5 6 8 17 18 20 ARSENOUS TRIIODIDE 4171 # ARSENIC PENTAFLUORIDE 7784-36-3 1556 CA 1 2 3 4 6 8 15 17 18 20 ARSORANE, PENTAFLUORO- 0158 # ARSENIC PENTOXIDE 1303-28-2 1559 CA 1 2 3 4 5 6 7 8 14 15 17 18 19 ARSENIC OXIDE (As2O5) 20 21 0159 # ARSENIC TRICHLORIDE 7784-34-1 1560 CA 1 2 3 4 5 6 8 14 15 17 18 19 20 ARSENOUS TRICHLORIDE 22 0161 # ARSENIC TRIOXIDE 1327-53-3 1561 CA 1 2 3 4 5 6 7 8 14 15 17 18 19 ARSENIC OXIDE (As2O3) 20 21 0162 # ARSENIC TRISULFIDE 1303-33-9 1557 CA 1 2 3 4 5 6 7 8 14 15 17 18 20 ARSENIC SULFIDE (As2S3) Page 4 of 55 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 0163 # ARSINE 7784-42-1 2188 CA F4 R2 1 2 3 4 5 6 7 8 15 17 19 22 ARSINE 0164 # ASBESTOS 1332-21-4 2212 CA 1 2 3 4 5 6 7 8 17 18 20 ASBESTOS 3170 # ASBESTOS, ACTINOLITE see Fact Sheet # 0164 on ASBESTOS 77536-66-4 2212 CA 1 2 3 4 5 6 7 17 ASBESTOS, ACTINOLITE 0165 # ASBESTOS, AMOSITE see Fact Sheet # 0164 on ASBESTOS 12172-73-5 2212 CA 1 2 3 4 5 6 7 8 17 ASBESTOS, GRUNERITE 0166 # ASBESTOS, ANTHOPHYLLITE see Fact Sheet # 0164 on ASBESTOS 77536-67-5 2212 CA 1 2 3 4 5 6 7 8 17 ASBESTOS, ANTHOPHYLLITE 0167 # ASBESTOS, CHRYSOTILE see Fact Sheet # 0164 on ASBESTOS 12001-29-5 2212 CA 1 2 3 4 5 6 7 17 ASBESTOS, CHRYSOTILE 0168 # ASBESTOS, CROCIDOLITE see Fact Sheet # 0164 on ASBESTOS 12001-28-4 2212 CA 1 2 3 4 5 6 7 17 ASBESTOS, CROCIDOLITE 3283 # ASBESTOS, TREMOLITE see Fact Sheet # 0164 on ASBESTOS 77536-68-6 2212 CA 1 2 3 4 5 7 17 ASBESTOS, TREMOLITE 3197 # ASPHALT, OXIDIZED 64742-93-4 1999 CA 2 3 4 7 15 17 ASPHALT, OXIDIZED Page 5 of 55 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 2894 # AURAMINE 492-80-8 1602 CA 3 6 7 17 18 20 21 BENZENAMINE, 4,4'-(CARBONIMIDOYLBIS[N,N-DIMETHYL- 0173 # AZASERINE 115-02-6 3077 CA 3 7 17 20 21 L-SERINE, DIAZOACETATE (ESTER) 3176 # AZOBENZENE 103-33-3 CA 7 8 DIAZENE, DIPHENYL- 3074 # BARIUM CHROMATE 10294-40-3 1564 CA 1 2 3 4 5 6 7 8 17 18 20 CHROMIC ACID (H2CrO4), BARIUM SALT (1:1) 4082 # BASIC LEAD CHROMATE, ORANGE 1344-38-3 3077 CA 1 2 3 4 5 6 7 8 17 18 20 C.I. PIGMENT ORANGE 21 0195 # BENZAL CHLORIDE 98-87-3 1886 CA 3 6 7 17 18 19 20 21 BENZENE, (DICHLOROMETHYL)- 0193 # BENZ(a)ANTHRACENE 56-55-3 3077 CA MU 1 2 3 4 5 6 7 8 17 18 20 21 BENZ[a]ANTHRACENE 0194 # BENZ(a)ANTHRACENE, 7,12-DIMETHYL- 57-97-6 3077 CA MU TE 3 6 17 18 20 21 BENZ[a]ANTHRACENE, 7,12-DIMETHYL- 0197 # BENZENE 71-43-2 1114 CA MU F3 1 2 3 4 5 6 7 8 15 17 18 20 21 BENZENE Page 6 of 55 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 0204 # BENZIDINE 92-87-5 1885 CA MU 1 2 3 4 5 6 7 8 17 18 20 21 [1,1'-BIPHENYL]-4,4'-DIAMINE 4195 # BENZIDINE DIHYDROCHLORIDE 531-85-1 CA 7 [1,1'-BIPHENYL]-4,4' -DIAMINE, DIHYDROCHLORIDE 4196 # BENZIDINE HYDROCHLORIDE 14414-68-7 CA 7 [1,1'-BIPHENYL]-4,4' -DIAMINE, HYDROCHLORIDE 4197 # BENZIDINE SULFATE 531-86-2 CA 7 [1,1'-BIPHENYL]-4,4' -DIAMINE, SULFATE 0208 # BENZO(b)FLUORANTHENE 205-99-2 3077 CA 2 3 5 6 7 8 17 18 20 BENZ[e]ACEPHENANTHRYLENE 0210 # BENZO(j)FLUORANTHENE 205-82-3 3077 CA 3 5 6 7 17 18 BENZO[j]FLUORANTHENE 2969 # BENZO(k)FLUORANTHENE 207-08-9 3082 CA 3 5 6 7 8 17 18 20 BENZO[k]FLUORANTHENE 0207 # BENZO(a)PYRENE 50-32-8 3077 CA MU 1 2 3 4 5 6 7 8 17 18 20 21 BENZO[a]PYRENE 0212 # BENZOTRICHLORIDE 98-07-7 2226 CA CO 2 3 5 6 7 8 15 17 18 19 20 21 BENZENE, (TRICHLOROMETHYL)- Page 7 of 55 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 0214 # BENZOYL CHLORIDE 98-88-4 1736 CA CO R2 2 3 6 7 15 17 18 20 BENZOYL CHLORIDE 0217 # BENZYL CHLORIDE 100-44-7 1738 CA CO MU 1 2 3 4 6 7 8 15 17 18 19 20 21 BENZENE, (CHLOROMETHYL)- 3190 # BENZYL VIOLET 4B 1694-09-3 CA 7 BENZENEMETHANAMINIUM, N-[4-[[4-DIMETHYLAMINO)PHENYL][4-[ETHYL[(3- SULFOPHENYL)METHYL]AMINO]PHENYL]METHYLENE]-2,5-CYCLOHEXADIEN-1-YLIDENE]-N-ETHYL-3-SULFO-, INNER SALT, SODIUM SALT 3080 # BERYL 1302-52-9 1566 CA 1 2 3 4 5 6 7 8 17 18 20 BERYL (Al2Be3(SiO3)6) 0222 # BERYLLIUM 7440-41-7 1567 CA 1 2 3 4 5 6 7 8 15 17 18 20 21 BERYLLIUM 3088 # BERYLLIUM CARBONATE 66104-24-3 1566 CA 1 2 3 4 5 6 7 8 17 18 20 BERYLLIUM CARBONATE HYDROXIDE (Be3(CO3)2(OH)2) 0223 # BERYLLIUM CHLORIDE 7787-47-5 1566 CA 1 2 3 4 5 6 7 8 17 18 20 BERYLLIUM CHLORIDE (BeCl2) 2163 # BERYLLIUM COMPOUNDS 1566 CA 1 2 3 4 5 6 7 8 17 18 20 0224 # BERYLLIUM FLUORIDE 7787-49-7 1566 CA 1 2 3 4 5 6 7 8 17 18 20 BERYLLIUM FLUORIDE (BeF2) Page 8 of 55 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 3083 # BERYLLIUM HYDROXIDE 13327-32-7 1566 CA 1 2 3 4 5 6 7 8 17 18 20 BERYLLIUM HYDROXIDE (Be(OH)2) 0225 # BERYLLIUM NITRATE 13597-99-4 2464 CA 1 2 3 4 5 6 7 8 17 18 20 NITRIC ACID, BERYLLIUM SALT 4097 # BERYLLIUM NITRATE TETRAHYDRATE 13510-48-0 1566 CA 1 2 3 4 5 6 7 8 17 18 20 NITRIC ACID, BERYLLIUM SALT, TETRAHYDRATE 4101 # BERYLLIUM NITRATE TRIHYDRATE 7787-55-5 1566 CA 1 2 3 4 5 6 7 8 17 18 20 NITRIC ACID, BERYLLIUM SALT, TRIHYDRATE 0226 # BERYLLIUM OXIDE 1304-56-9 1566 CA 1 2 3 4 5 6 7 8 17 18 20 BERYLLIUM OXIDE (BeO) 3191 # BERYLLIUM PHOSPHATE 13598-15-7 1566 CA 1 2 3 4 5 6 7 8 17 18 20 PHOSPHORIC ACID, BERYLLIUM SALT (1:1) 4091 # BERYLLIUM SILICATE 13598-00-0 1566 CA 1 2 3 4 5 6 7 8 17 18 20 PHENAKITE 3084 # BERYLLIUM SULFATE 13510-49-1 1566 CA 1 2 3 4 5 6 7 8 17 18 20 SULFURIC ACID, BERYLLIUM SALT (1:1) 3091 # BERYLLIUM SULFATE TETRAHYDRATE 7787-56-6 1566 CA 1 2 3 4 5 6 7 8 17 18 20 SULFURIC ACID, BERYLLIUM SALT (1:1), TETRAHYDRATE Page 9 of 55 2010 Right to Know Special Health Hazardous Substance List Substance Common Name Carcinogens CAS DOT SHHC Sources Number Chemical Name 4099 # 2,2-BIS(BROMOMETHYL)-1,3-PROPANEDIOL 3296-90-0 CA 5 7 1,3-PROPANEDIOL, 2,2-BIS(BROMOMETHYL)- 0232 # BIS (2-CHLOROETHYL) ETHER 111-44-4 1916 CA 1 2 3 4 6 7 8 15 17 18 19 20 21 ETHANE, 1,1'-OXYBIS[2-CHLORO- 0234 # BIS(CHLOROMETHYL)ETHER 542-88-1 2249 CA F3 1 2 3 4 5 6 7 8 15 17 18 19 20 METHANE, OXYBIS[CHLORO- 21 22 0237 # BIS(2-ETHYLHEXYL)ADIPATE 103-23-1
Recommended publications
  • COMBINED LIST of Particularly Hazardous Substances
    COMBINED LIST of Particularly Hazardous Substances revised 2/4/2021 IARC list 1 are Carcinogenic to humans list compiled by Hector Acuna, UCSB IARC list Group 2A Probably carcinogenic to humans IARC list Group 2B Possibly carcinogenic to humans If any of the chemicals listed below are used in your research then complete a Standard Operating Procedure (SOP) for the product as described in the Chemical Hygiene Plan. Prop 65 known to cause cancer or reproductive toxicity Material(s) not on the list does not preclude one from completing an SOP. Other extremely toxic chemicals KNOWN Carcinogens from National Toxicology Program (NTP) or other high hazards will require the development of an SOP. Red= added in 2020 or status change Reasonably Anticipated NTP EPA Haz list COMBINED LIST of Particularly Hazardous Substances CAS Source from where the material is listed. 6,9-Methano-2,4,3-benzodioxathiepin, 6,7,8,9,10,10- hexachloro-1,5,5a,6,9,9a-hexahydro-, 3-oxide Acutely Toxic Methanimidamide, N,N-dimethyl-N'-[2-methyl-4-[[(methylamino)carbonyl]oxy]phenyl]- Acutely Toxic 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl-CCNU) Prop 65 KNOWN Carcinogens NTP 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) IARC list Group 2A Reasonably Anticipated NTP 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) (Lomustine) Prop 65 1-(o-Chlorophenyl)thiourea Acutely Toxic 1,1,1,2-Tetrachloroethane IARC list Group 2B 1,1,2,2-Tetrachloroethane Prop 65 IARC list Group 2B 1,1-Dichloro-2,2-bis(p -chloropheny)ethylene (DDE) Prop 65 1,1-Dichloroethane
    [Show full text]
  • Indene CH Activation, Indole Π Vs. Nitrogen Lone-Pair Coordinati
    HHS Public Access Author manuscript Author ManuscriptAuthor Manuscript Author Organometallics Manuscript Author . Author Manuscript Author manuscript; available in PMC 2016 April 15. Published in final edited form as: Organometallics. 2007 ; 26(2): 281–287. doi:10.1021/om0606643. Reactions of Indene and Indoles with Platinum Methyl Cations: Indene C-H Activation, Indole π vs. Nitrogen Lone-Pair Coordination Travis J. Williams, Jay A. Labinger, and John E. Bercaw Arnold and Mabel Beckman Laboratories of Chemical Synthesis, California Institute of Technology, Pasadena, CA 91125 (U. S. A.) Abstract Reactions of indene and various substituted indoles with [(diimine)PtII(Me)(TFE)]+ cations have been studied (diimine = ArN = C(Me) − C(Me) = NAr; TFE = 2,2,2-trifluoroethanol). Indene displaces the TFE ligand from platinum to form a stable π coordination complex that, upon heating, undergoes C-H activation with first order kinetics, ΔH‡ = 29 kcal/mol, ΔS‡ = 10 eu, and a kinetic isotope effect of 1.1 at 60 °C. Indoles also initially form coordination complexes through the C2=C3 olefin, but these undergo rearrangement to the corresponding N-bound complexes. The relative rates of initial coordination and rearrangement are affected by excess acid or methyl substitution on indole. Introduction Selective C-H bond activation is a potentially valuable approach to synthetic problems in areas ranging from fuels and bulk chemicals to fine chemicals and pharmaceutical synthesis. 1 Studies of C-H activation in our laboratory have focused on models of the Shilov system,2 particularly [(diimine)PtII(Me)(solv)]+ (2, diimine = ArN = C(Me) − C(Me) = NAr; solv = 2,2,2-trifluoroethanol (TFE), H2O).3 These cations are capable of activating a variety of II carbon-hydrogen bonds.4 Cations 2 can be generated by protonolysis of (diimine)Pt Me2 species 1 in TFE with aqueous HBF43, 4ab or BX3 (X = C6F5,4cd F5), the latter producing H+ by boron coordination to TFE.4c In deuterated solvent 2 is formed as a mixture of two isotopologs.
    [Show full text]
  • Chemical Hygiene Plan Manual
    CHEMICAL HYGIENE PLAN AND HAZARDOUS MATERIALS SAFETY MANUAL FOR LABORATORIES This is the Chemical Hygiene Plan specific to the following areas: Laboratory name or room number(s): ___________________________________ Building: __________________________________________________________ Supervisor: _______________________________________________________ Department: _______________________________________________________ Telephone numbers 911 for Emergency and urgent consultation 48221 Police business line 46919 Fire Dept business line 46371 Radiological and Environmental Management Revisied on: Enter a revision date here. All laboratory chemical use areas must maintain a work-area specific Chemical Hygiene Plan which conforms to the requirements of the OSHA Laboraotry Standard 29 CFR 19190.1450. Purdue University laboratories may use this document as a starting point for creating their work area specific CHP. Minimally this cover page is to be edited for work area specificity (non-West Lafayette laboratories are to place their own emergency, fire, and police telephone numbers in the space above) AND appendix K must be completed. This instruction and information box should remain. This model CHP is version 2010A; updates are to be found at www.purdue.edu/rem This page intentionally blank. PURDUE CHEMICAL HYGIENE PLAN AWARENESS CERTIFICATION For CHP of: ______________________________ Professor, building, rooms The Occupational Safety and Health Administration (OSHA) requires that laboratory employees be made aware of the Chemical Hygiene Plan at their place of employment (29 CFR 1910.1450). The Purdue University Chemical Hygiene Plan and Hazardous Materials Safety Manual serves as the written Chemical Hygiene Plan (CHP) for laboratories using chemicals at Purdue University. The CHP is a regular, continuing effort, not a standby or short term activity. Departments, divisions, sections, or other work units engaged in laboratory work whose hazards are not sufficiently covered in this written manual must customize it by adding their own sections as appropriate (e.g.
    [Show full text]
  • Biochemical and Pathological Effects of Methylazoxymethanol Acetate, a Potent Carcinogen1
    [CANCER RESEARCH 30, 801-812, March 1970] Biochemical and Pathological Effects of Methylazoxymethanol Acetate, a Potent Carcinogen1 Morris S. Zedeck, Stephen S. Sternberg, Richard W. Poynter, and Jane McGowan Divisions of Pharmacology and Cytology, Sloan-Kettering Institute for Cancer Research, New York, New York 10021 SUMMARY vealed that the agent is cleaved by the intestinal flora which possess a 0-o-glucosidase, and that the free agly Methylazoxymethanol acetate is known to induce tu cone methylazoxymethanol is the active carcinogen (13- mors in rodents. Effects produced by a single nonlethal 15, 34). Matsumoto et al. (19) synthesized MAM acetate3 dose on nucleic acid and protein synthesis have been in (Chart 1), which is stable and not dependent upon vestigated in rat and mouse liver, small intestine, and ,0-glucosidase cleavage for activity. Single or only a few kidney, the 3 organs most susceptible to carcinogenesis. doses of cycasin, or of the aglycone methylazoxymetha The agent induced early inhibition of thymidine incor nol, are required to induce tumors in rats which are pri poration into DNA of rat tissues. Rat liver was most sen marily of the kidney, intestinal tract, and liver (11, 15). sitive to this effect and was the only organ to show marked Aqueous extracts of cycad nut have also been shown to inhibition of RNA and protein synthesis. In mice, liver induce tumors of liver and kidneys in mice (21). The was more sensitive than small intestine or kidney and ex present investigation was undertaken to study the acute hibited an inhibition of RNA and protein synthesis; there pathological and biochemical effects produced by MAM were no changes observed in small intestine or kidney.
    [Show full text]
  • Carbon Tetrachloride
    CARBON TETRACHLORIDE Data were last reviewed in IARC (1979) and the compound was classified in IARC Monographs Supplement 7 (1987a). 1. Exposure Data 1.1 Chemical and physical data 1.1.1 Nomenclature Chem. Abstr. Serv. Reg. No.: 56-23-5 Chem. Abstr. Name: Tetrachloromethane IUPAC Systematic Name: Carbon tetrachloride Synonyms: Benzinoform; carbona 1.1.2 Structural and molecular formulae and relative molecular mass Cl Cl CCl Cl CCl4 Relative molecular mass: 153.82 1.1.3 Chemical and physical properties of the pure substance (a) Description: Colourless, clear, nonflammable, liquid with a characteristic odour (Budavari, 1996) (b) Boiling-point: 76.8°C (Lide, 1997) (c) Melting-point: –23°C (Lide, 1997) (d) Solubility: Very slightly soluble in water (0.05% by volume); miscible with benzene, chloroform, diethyl ether, carbon disulfide and ethanol (Budavari, 1996) (e) Vapour pressure: 12 kPa at 20°C; relative vapour density (air = 1), 5.3 at the boiling-point (American Conference of Governmental Industrial Hygienists, 1991) (f) Conversion factor: mg/m3 = 6.3 × ppm 1.2 Production and use Production in the United States in 1991 was reported to be approximately 143 thousand tonnes (United States International Trade Commission, 1993). Information –401– 402 IARC MONOGRAPHS VOLUME 71 available in 1995 indicated that carbon tetrachloride was produced in 24 countries (Che- mical Information Services, 1995). Carbon tetrachloride is used in the synthesis of chlorinated organic compounds, including chlorofluorocarbon refrigerants. It is also used as an agricultural fumigant and as a solvent in the production of semiconductors, in the processing of fats, oils and rubber and in laboratory applications (Lewis, 1993; Kauppinen et al., 1998).
    [Show full text]
  • Customer Information Regarding Material Resistance in Compressed Air Preparation
    Customer information regarding material resistance in compressed air preparation Polycarbonate reservoirs for filter regulators, filters, and lubricators Everywhere the presence of these media cannot be avoided, such as in paint booths, gluing machines, Polycarbonate is the longest known and most vulcanization plants, etc., the use of metal reservoirs processed material in the world for reservoirs of is required. compressed air maintenance units. The high Problematic is the use of solvents not only in pressure and temperature resistances, as well as immediate contact with the reservoir, but also in its good compatibility with the normally used media immediate vicinity. For example, trichlorethylene such as water, oils and greases are some of its vapors from the compressor’s intake air can cause advantages. crack formation in the polycarbonate reservoir. Only The only “weakness” of this plastic is its clean the reservoirs using a slightly damp cloth. Only susceptibility to media that can be referred to use water to do this and, if necessary, a mild collectively using the term “solvents”. From this detergent without chemical additives. range, the materials relevant to the use of If a lubricator is used, please only use suitable compressed air preparation units are summarized pneumatic oils, e.g. AVENTICS pneumatic oil, order here: no. 8982000010 – 1L. Detergents : Trichloroethylene, (usually from outside) perchloroethylene, In most cases, the use of (pneumatic) oils with benzene, additives, for example antifreeze, results in damage super/regular gasoline to or destruction of the reservoirs and must thus be avoided. Alternatively, we recommend the use of Solvents : Acetone, metal reservoirs. (from outside/inside) paint thinners, alcohols, esters Polycarbonate can react to permanent UV-light irradiation and weathering.
    [Show full text]
  • 1/2 Toxic Compound Data Sheet Name: Indene CAS Number: 00095
    1/2 Toxic Compound Data Sheet Name: Indene CAS Number: 00095-13-6 Justification: This compound is listed in Ohio Administrative Code 3745 - 114 - 01 because it fulfills one or more of the following criteria: substances that are known to be, or may reasonably be anticipated to be, carcinogenic, mutagenic, teratogenic, or neurotoxic, causes reproductive dysfunction, is acutely or chronically toxic, or causes the threat of adverse environmental effects through ambient concentrations, bioaccumulation, or atmospheric deposition. lndene is acutely toxic with effects on the upper respiratory system (mucous membranes), pulmonary irritation, liver and kidney effects. Molecular Weight (g/mol): 116.15 Synonyms: Indonaphthene U.S. EPA Carcinogenic Classification (IRIS): Not listed on IRIS. PBT: Not listed as persistent, bioaccumulative and toxic. NTP: Not listed by the National Toxicology Program. HAP: Not listed as a hazardous air pollutant (HAP) by U.S. EPA. 112r: Not listed under Section 112(r) of the Clean Air Act. ACGIH: TLV: 10 ppm or 47,505 µg/m3. Critical effects include upper respiratory irritation or damage, pulmonary irritation, and liver and kidney effects. HSDB: Listed in the Hazardous Substances Data Bank. Inhalation of indene vapors is expected to cause irritation of mucous membranes. International IARC: Not listed by International Agency for Research on Cancer (IARC). ATSDR (MRL): Not listed by ATSDR. DataSheet Indene.wpd 2/2 Reference Material 1. American Conference of Governmental Industrial Hygienists (ACGIH) 2006. TLVs and BEIs:
    [Show full text]
  • Using SMILES Strings for the Description of Chemical Connectivity in the Crystallography Open Database
    Quirós et al. J Cheminform (2018) 10:23 https://doi.org/10.1186/s13321-018-0279-6 RESEARCH ARTICLE Open Access Using SMILES strings for the description of chemical connectivity in the Crystallography Open Database Miguel Quirós1* , Saulius Gražulis2,3 , Saulė Girdzijauskaitė3, Andrius Merkys2 and Antanas Vaitkus2 Abstract Computer descriptions of chemical molecular connectivity are necessary for searching chemical databases and for predicting chemical properties from molecular structure. In this article, the ongoing work to describe the chemical connectivity of entries contained in the Crystallography Open Database (COD) in SMILES format is reported. This col- lection of SMILES is publicly available for chemical (substructure) search or for any other purpose on an open-access basis, as is the COD itself. The conventions that have been followed for the representation of compounds that do not ft into the valence bond theory are outlined for the most frequently found cases. The procedure for getting the SMILES out of the CIF fles starts with checking whether the atoms in the asymmetric unit are a chemically accept- able image of the compound. When they are not (molecule in a symmetry element, disorder, polymeric species,etc.), the previously published cif_molecule program is used to get such image in many cases. The program package Open Babel is then applied to get SMILES strings from the CIF fles (either those directly taken from the COD or those produced by cif_molecule when applicable). The results are then checked and/or fxed by a human editor, in a computer-aided task that at present still consumes a great deal of human time.
    [Show full text]
  • The Chiba System 千葉方式 : a Non Toxic Alternative to the Dichromate
    The Chiba System 千葉方式 A Non Toxic Alternative to the Dichromate Processes January 2007 Halvor Bjoerngaard Graduate School of Science and Technology CHIBA UNIVERSITY (千葉大学学位申請論文) The Chiba System 千葉方式 : A Non Toxic Alternative to the Dichromate Processes or The Production of Photographic Prints in Permanent Pigments by Utilising the Sensitivity of the Ferric Salt to the Spectre and Employing the Polymerization of Colloids. 2007年1月 千葉大学大学院自然科学研究科 情報科学専攻画像科学 Halvor Bjørngård Abstract This study has the main purpose of presenting a non-toxic, or an alternative, printing system for the dichromate based pigment processes. The two methods presented in depth are modelled on first Carbon printing then Gum Printing. Achieving non-toxicity for these systems means replacing the dichromate sensitizer and secondly to avoid the practise of hardening the substrate. An alternative sensitizer is presented and hardening is avoided by using modified working methods. The chemistry utilised for this purpose is iron based, red-ox induced, free radical polymerization. The sensitizer is ammonium ferric citrate, using either hydrogen peroxide or ammonium persulphate as developer. For Carbon Printing a solution to both the need for hardeners and the problem of oxygen inhibition, which is usual for this kind of polymerisation, is achieved. This is done by using a covering layer of agar-agar that blocks oxygen and changes the transfer system, obsolescing the use of hardeners. For Gum Printing two methods are presented. One is based on gelatine, which allows the use of a hydrogen peroxide bath for development. The second method is with gum arabicum, which necessitates inclusion of ammonium persulphate in the coating as a developing agent.
    [Show full text]
  • Prohibited and Restricted Chemical List
    School Emergency Response Plan and Management Guide Prohibited and Restricted Chemical List PROHIBITED AND RESTRICTED CHEMICAL LIST Introduction After incidents of laboratory chemical contamination at several schools, DCPS, The American Association for the Advancement of Science (AAAS) and DC Fire and Emergency Management Services developed an aggressive program for chemical control to eliminate student and staff exposure to potential hazardous chemicals. Based upon this program, all principals are required to conduct a complete yearly inventory of all chemicals located at each school building to identify for the removal and disposal of any prohibited/banned chemicals. Prohibited chemicals are those that pose an inherent, immediate, and potentially life- threatening risk, injury, or impairment due to toxicity or other chemical properties to students, staff, or other occupants of the school. These chemicals are prohibited from use and/or storage at the school, and the school is prohibited from purchasing or accepting donations of such chemicals. Restricted chemicals are chemicals that are restricted by use and/or quantities. If restricted chemicals are present at the school, each storage location must be addressed in the school's written emergency plan. Also, plan maps must clearly denote the storage locations of these chemicals. Restricted chemicals—demonstration use only are a subclass in the Restricted chemicals list that are limited to instructor demonstration. Students may not participate in handling or preparation of restricted chemicals as part of a demonstration. If Restricted chemicals—demonstration use only are present at the school, each storage location must be addressed in the school's written emergency plan. Section 7: Appendices – October 2009 37 School Emergency Response Plan and Management Guide Prohibited and Restricted Chemical List Following is a table of chemicals that are Prohibited—banned, Restricted—academic curriculum use, and Restricted—demonstration use only.
    [Show full text]
  • Table 2. Chemical Names and Alternatives, Abbreviations, and Chemical Abstracts Service Registry Numbers
    Table 2. Chemical names and alternatives, abbreviations, and Chemical Abstracts Service registry numbers. [Final list compiled according to the National Institute of Standards and Technology (NIST) Web site (http://webbook.nist.gov/chemistry/); NIST Standard Reference Database No. 69, June 2005 release, last accessed May 9, 2008. CAS, Chemical Abstracts Service. This report contains CAS Registry Numbers®, which is a Registered Trademark of the American Chemical Society. CAS recommends the verification of the CASRNs through CAS Client ServicesSM] Aliphatic hydrocarbons CAS registry number Some alternative names n-decane 124-18-5 n-undecane 1120-21-4 n-dodecane 112-40-3 n-tridecane 629-50-5 n-tetradecane 629-59-4 n-pentadecane 629-62-9 n-hexadecane 544-76-3 n-heptadecane 629-78-7 pristane 1921-70-6 n-octadecane 593-45-3 phytane 638-36-8 n-nonadecane 629-92-5 n-eicosane 112-95-8 n-Icosane n-heneicosane 629-94-7 n-Henicosane n-docosane 629-97-0 n-tricosane 638-67-5 n-tetracosane 643-31-1 n-pentacosane 629-99-2 n-hexacosane 630-01-3 n-heptacosane 593-49-7 n-octacosane 630-02-4 n-nonacosane 630-03-5 n-triacontane 638-68-6 n-hentriacontane 630-04-6 n-dotriacontane 544-85-4 n-tritriacontane 630-05-7 n-tetratriacontane 14167-59-0 Table 2. Chemical names and alternatives, abbreviations, and Chemical Abstracts Service registry numbers.—Continued [Final list compiled according to the National Institute of Standards and Technology (NIST) Web site (http://webbook.nist.gov/chemistry/); NIST Standard Reference Database No.
    [Show full text]
  • 2019 Minnesota Chemicals of High Concern List
    Minnesota Department of Health, Chemicals of High Concern List, 2019 Persistent, Bioaccumulative, Toxic (PBT) or very Persistent, very High Production CAS Bioaccumulative Use Example(s) and/or Volume (HPV) Number Chemical Name Health Endpoint(s) (vPvB) Source(s) Chemical Class Chemical1 Maine (CA Prop 65; IARC; IRIS; NTP Wood and textiles finishes, Cancer, Respiratory 11th ROC); WA Appen1; WA CHCC; disinfection, tissue 50-00-0 Formaldehyde x system, Eye irritant Minnesota HRV; Minnesota RAA preservative Gastrointestinal Minnesota HRL Contaminant 50-00-0 Formaldehyde (in water) system EU Category 1 Endocrine disruptor pesticide 50-29-3 DDT, technical, p,p'DDT Endocrine system Maine (CA Prop 65; IARC; IRIS; NTP PAH (chem-class) 11th ROC; OSPAR Chemicals of Concern; EuC Endocrine Disruptor Cancer, Endocrine Priority List; EPA Final PBT Rule for 50-32-8 Benzo(a)pyrene x x system TRI; EPA Priority PBT); Oregon P3 List; WA Appen1; Minnesota HRV WA Appen1; Minnesota HRL Dyes and diaminophenol mfg, wood preservation, 51-28-5 2,4-Dinitrophenol Eyes pesticide, pharmaceutical Maine (CA Prop 65; IARC; NTP 11th Preparation of amino resins, 51-79-6 Urethane (Ethyl carbamate) Cancer, Development ROC); WA Appen1 solubilizer, chemical intermediate Maine (CA Prop 65; IARC; IRIS; NTP Research; PAH (chem-class) 11th ROC; EPA Final PBT Rule for 53-70-3 Dibenzo(a,h)anthracene Cancer x TRI; WA PBT List; OSPAR Chemicals of Concern); WA Appen1; Oregon P3 List Maine (CA Prop 65; NTP 11th ROC); Research 53-96-3 2-Acetylaminofluorene Cancer WA Appen1 Maine (CA Prop 65; IARC; IRIS; NTP Lubricant, antioxidant, 55-18-5 N-Nitrosodiethylamine Cancer 11th ROC); WA Appen1 plastics stabilizer Maine (CA Prop 65; IRIS; NTP 11th Pesticide (EPA reg.
    [Show full text]