Indian Council of Medical Research New Delhi © 2005 Indian Council of Medical Research
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Annual Report 2003-2004 Indian Council of Medical Research New Delhi © 2005 Indian Council of Medical Research Prof. N.K. Ganguly: Director-General Dr. K. Satyanarayana: Chief (Publication & Information) Complied and Edited by Dr. Sudha Chauhan, DDG (SG) Published by the Division of Publication, Information and Communication on behalf of the Director-General, Indian Council of Medical Research New Delhi 110029 Layout Design & Production Control by ICMR Press Unit Printed at: S. Narayan & Sons, B-88, Okhla Indl. Area, Phase-II, New Delhi Tel: 26385873 he Indian Council of Medical Research has made significant strides in its mandate of ‘Research for TBetter Health’. The Council has lived up to country’s expectations on all major fronts of its activity: research and development of vaccines and drugs for infectious diseases like tuberculosis, malaria, filariasis, HIV/AIDS, research in the areas of modern biology like molecular biology, genomics, bioinformatics, fertility regulation, cancer and other non-communicable diseases, consultancy and human resource development, national and international collaborations and biomedical informatics and communication. During the period under report, the Memorandum for the Expenditure Finance Committee (EFC) of ICMR has been approved by the Government of India and Rs.870 Crores have been allocated for the 10th Plan. The research activities will now be pursued with greater vigour as more funding would be available. To optimize resource utilization, the Council is using the Combined Approach Matrix being used by Global Health Forum for Health Research for setting research priorities in various disciplines. The Council continued to play an important role in detecting new and emerging infections in India like the Chandipura virus encephalitis in Andhra Pradesh and Gujarat and outbreak of mysterious fever in Siliguri. The investigations carried out in collaboration with CDC, Atlanta on biological specimens collected from Siliguri in 2001 revealed that the outbreak was due to Nipah virus. An Inter-Agency collaboration has been started on herbal drugs between the Department of ISM/AYUSH, CSIR and the ICMR, popularly known as the “Golden Triangle’. A National Centre for Primate Breeding and Research is being established at Sasunavgher, Maharashtra. The Centre would function as a base for research, biological testing and breeding of primates. In order to improve access to scientific journals by various institutes of the ICMR, a J-Gate Custom Content for Consortia-ICMR @ JCCC has been set up. It will provide online access to more than 2000 biomedical journals and 12000 journals covered under J-Gate and will enhance sharing of journals available in ICMR Institutes. The publication output of ICMR continues to be outstanding. The scientists of the Council’s Institutes published a total of 434 research papers during 2003 as compared to 330 in 2002. The average impact factor per paper of ICMR improved to 2.180 from 2.030 in 2002. During the financial year 2003-04, over 1000 research projects were funded. Around 900 scientific, technical and supporting staff were trained during the period. Eight patents including one US patent were filed during the year. The quality of publications of ICMR such as the Indian Journal of Medical Research and Annual Report has improved. A biennial award scheme has been initiated for popular medical books published in Hindi. I am happy to present the Annual Report of the ICMR for the financial year 2003-04 giving highlights of activities during this period. Nirmal Kumar Ganguly Director-General OVERVIEW .......................................................................................................... 1 COMMUNICABLE DISEASES ................................................................................... 5 REPRODUCTIVE HEALTH ....................................................................................... 68 NUTRITION ......................................................................................................... 87 ENVIRONMENTAL AND OCCUPATIONAL HEALTH ....................................................... 93 NON-COMMUNICABLE DISEASES ............................................................................ 98 BASIC MEDICAL SCIENCES ................................................................................... 106 SUPPORTING FACILITIES ....................................................................................... 123 PUBLICATION, INFORMATION AND COMMUNICATION ................................................. 127 ICMR AWARDS AND PRIZES ................................................................................. 130 APPENDICES : I. ICMR Permanent Institutes/Centres ........................................................ 133 II. Regional Medical Research Centres .......................................................... 135 III. ICMR Centres for Advanced Research ...................................................... 136 IV. Training Programmes Conducted by ICMR Institutes during 2003-04 .. 137 V. Seminars/Symposia/Workshops/Conferences ............................................ 140 VI. List of Research Schemes Funded during 2003-2004............................... 148 VII. List of Fellowships Funded during 2003-2004.......................................... 207 VIII. List of Publications of ICMR Institutes ..................................................... 225 Better health through research The Indian Council of Medical Research (ICMR) shift some of the expenditure being made under has entered 93rd year in the service of nation. “Plan” to “Non-Plan” due to the static Non-Plan The Council continues to direct its resources in outlay. With the improvement in infrastructure conducting research towards finding feasible for conducting research in the Institutes, it has solutions to problems being encountered in been possible for them to attract larger number addressing India’s health problems. of Ph.D. students as compared to earlier years. The Council continues to support human The Memorandum for the Expenditure resources development through its training Finance Committee for utilizing the funds courses (regular as well as short term) in received from Departments of Health and that various institutes. of Family Welfare have been approved. The research activities outlined in the 10th plan Playing its stewardship role as a health document could now be pursued with greater research organization, the Council has used the vigour. This was not possible up to now as the Global Forum for Health Research (GFHR) ICMR’s annual allocations in the first two years Combined Approach Matrix for setting research of the 10th plan were almost equal to the last priorities in various disciplines. The estimation year of 9th Plan. It is expected that in the of disease burden using Murray and Lopez remaining part of the 10th plan this shortfall method for some infectious and non-infectious would be compensated with an adequate increase diseases was pursued. Due to variation in the in the allocations. completeness and quality of data available on disease incidence and prevalence coupled with The Council has stepped-up its funding for statistics obtained from the programme and the extramural research programme for which research studies with the problems associated close to 25% of the budget is being earmarked. in assigning disability and age weights, As part of its Extramural Research Programme, alternative strategies to estimate disease burden the Council supported over 1000 projects during are being thought of. Application of methods the year 2003-04. Laboratory studies constituted developed by Centre for Economic Policy about 40%, clinical studies 30%, epidemiological Research for tracking financial flows for health and operational studies 20%. Of Rs. 34 crores research in India indicated that the existing being spent in this programme, laboratory, system of keeping accounts did not permit clinical, epidemiological and operational studies disaggregation of expenditure on health constituted about 30% each. A large share of research. Thus differentiation of the spend on funding (46%) went to research institutions, service sector from research at tertiary level about 30% to medical colleges and 13% to health care facilities can not be done. universities. As part of this programme, large number of scientific (350), technical (500) and supporting staff (60) were trained. NEW AND EMERGING INFECTIONS Having improved the infrastructure in the The ICMR is playing an important role to Institutes/Centres in previous years, the focus detect new and emerging infections in India like this year has been on a larger allocation for the Chandipura virus encephalitis in Andhra supplies and consumables so that the Pradesh and parts of Gujarat. Investigations equipments could be put to optimal use. The carried out with the help of CDC, Atlanta, USA Council is spending a quarter of its budget on have indicated a strong possibility of the Siliguri pay and allowances. It has not been possible to Outbreak of mysterious fever of 2002 to be due Annual Report 2003-2004 1 ICMR Better health through research ICMR INSTITUTIONAL NETWORK ICMR 2 Annual Report 2003-2004 Better health through research to Nipah virus. In its attempt to step-up quality standards of Indian medicinal plants as research on these pathogens, the Microbial well as the first three volumes on Indian Containment Complex, Pune has been completed Medicinal Plants. and is now ready for commissioning. It is a state