J Food Sci Nutr Res 2019; 2 (4): 316-326 DOI: 10.26502/jfsnr.2642-11000030 Research Article The Feed of Local Beef Bone Marrow Substitution during Pregnancy affects the Increase in Growth Hormone Offsprings Production of Thirty and Sixty Days Old Mice I Made Tangkas1,4*, Ahmad Sulaeman1, Faisal Anwar1, Agik Suprayogi2, Sri Estuningsih3 1Department of Community Nutrition, Faculty of Human Ecology, Bogor Agriculture University, Bogor, Indonesia 2Department of Anatomy, Physiology and Pharmacology, Faculty of Veterinary Medicine Bogor Agriculture University, Bogor, Indonesia 3Pathology Reproductive Clinic Department, Faculty of Veterinary Medicine Bogor Agriculture University, Bogor, Indonesia 4Department of Chemistry Education, Faculty of Teacher Training and Education Tadulako University of Palu, Palu, Indonesia *Corresponding Author: I Made Tangkas, Department of Community Nutrition, Faculty of Human Ecology, Bogor Agriculture University, Bogor 16680, Indonesia, E-mail:
[email protected] Received: 04 October 2019; Accepted: 17 October 2019; Published: 21 October 2019 Citation: I Made Tangkas, Ahmad Sulaeman, Faisal Anwar, Agik Suprayogi, Sri Estuningsih. The Feed of Local Beef Bone Marrow Substitution during Pregnancy affects the Increase in Growth Hormone Offsprings Production of Thirty and Sixty Days Old Mice. Journal of Food Science and Nutrition Research 2 (2019): 316-326. Abstract Growth hormone (GH) deficiency during the growth pituitary cell proliferation seen from the potential of the phase will cause the disruption, especially in phases of mice gland that produces the GH. The design of the infant, childhood, and puberty. Local beef bone marrow research uses a complete randomized design (RAL) in Central Sulawesi of Indonesia contains fatty and with a single factor. Fifty female rats and twenty male amino acids, which needed for supporting the rats were adapted for two weeks after the estrus was proliferation of somatotroph cells of fetal pituitary.