ULLA FELDT-RASMUSSEN

Professor, Chief Physician, Department of Medical Endocrinology MD, DMSc (dr.med.)

CURRICULUM VITAE

May, 2020

1

Personal information

Ulla Feldt-Rasmussen, MD, DMSc Professor, Chief Physician, Department of Medical Endocrinology PE 2132 Rigshospitalet, Blegdamsvej 9 2100 Copenhagen Denmark

Born: 24 September 1950 Home address: Baunegårdsvej 21, 2820 Gentofte, Denmark

Phone: +45 35452337/ +45 35451023 Home: +45 39615816 Fax: +45 35452240 Mobile: +45 24600158 E-mail: [email protected] Home: [email protected]

Employment history

• Department of Clinical Chemistry, Odense University Hospital Fellow (1974-1975); Resident (1975-1978); Researcher (1974-1978) • Faculty of Health Sciences, Odense University, Fellow (1978-1979) • Department of Medical Endocrinology, Herlev Hospital, Copenhagen University Resident (1979-1982); Consultant and Senior Lecturer (1987-1990); Senior Scientist (1987- 1990) • Consultant Advisor Europaeiske Travel Insurance and SOS International (1985-Present) • Hvidoere Hospital (diabetes hospital) Consultant and Senior Lecturer (1982-1983) • Department of Medical Endocrinology, Frederiksberg Hospital, Copenhagen University Consultant, Senior Lecturer and Senior Scientist (1983-1986) • Department of Internal Medicine, Gentofte Hospital, Copenhagen University Consultant and Senior Lecturer (1986-1987) • Rigshospitalet, Copenhagen University Hospital Head of Department and Senior Scientist (1990-present) • Faculty of Health Sciences, Copenhagen University Senior Lecturer (1980-1985); Associate Professor (1985-2010), Clinical Professor (2010- Present) • Consultant Advisor for Danish Agency for Patient Complaints (2016-Present)

Qualifications

• DMSc - Doctor of Medical Sciences (dr. med) 1983 Title of dissertation: "Serum Thyroglobulin and Thyroglobulin Autoantibodies in Thyroid Diseases. Pathogenic and Diagnostic Aspects" • Specialist in Endocrinology and Metabolism 1987 • Specialist in Internal Medicine 1987 • Qualified for professorship in Medical Endocrinology and Internal Medicine Copenhagen University 1992

2 • Qualified as Research Professor by Danish National Research Agency 2003 • Qualified for professorship in Medical Endocrinology and Internal Medicine Copenhagen University 2010

Administration

• Head of the Research Laboratory at Lab of Medical Endocrinology, Rigshospitalet 1990- present • Head of Department of Medical Endocrinology PE, Rigshospitalet 1990 – 2010 • Management and leadership (H:S course) 2005 • Administrative Course on 'Service and Management' 1986 • Course in Administrative medicine SOSA (1982)

Administrative and Academic Positions of Trust

• Endocrine Society Clinical Guidelines Task Force (2018- ongoing) • Member of Academic Council subcommittee at Copenhagen University selecting Review Committees for DSc theses (2018-present) • Danish leading participant of EU European Group for Endocrine Rare disease ERN (2016- present) • American Thyroid Association Public Health Committee (2012- present) • Member of Scientific Board of Ydes Foundation (2014 – present) • Chairman of the Research Foundation of Danish Medical Association (2013 -2020) • International Leader of Research Group on internationalization of the thyroid related quality of life questionnaire ThyPRO (2013-present) • Member of Regional Ethics Committee (Region A) (2004 – present) • Member of Scientific Board of Eva Madura's Research Foundation (2008 - present) • Strategic Research Board, Danish Regions. Board Member (2008-2013) • MTV Strategic Council, Danish Health Board. Board Member (2007-2013) • National Danish Health Institute. Board Member (2007-2012) • Member of Scientific Board of Freddy and Kirsten Johansen's Research Foundation for medical research (2006-2020) • Danish Research Council. Member (2005-2013) • Danish Committees on Scientific Dishonesty. Board Member (2004-2015) • Fabry Registry, Advisory Board. Member (2002 - present) • Genetic Board, Rigshospitalet. Member (2000 - present) • Quality Board (Kvalitetsråd), Rigshospitalet. Member (2000-2003) • Board of Physicians, Rigshospitalet. Director (1997-2003) • Health Board for Clinical Biochemistry: Genetic Diagnostics in Clinical Biochemistry. Rigshospitalet. Member (1997-1998) • Research Council, Rigshospitalet. Board Member (1997-present) • Member of Clinical Public Affairs Board; Danish Endocrine Society (1997) • Honorary auditor for the accounts of European Thyroid Association (1997) • Member of National Academy of Clinical Biochemistry guidelines Board on thyroid Hormones and other thyroid related substances (1996) • Pfizer, KIMS Executive Advisory Board Member (1996-2005) • Board of Physicians, Rigshospitalet. Deputy Director (1995-1997) • Diabetes Council, Copenhagen (Diabetesudvalg/H:S) Member (1995-2000) • Copenhagen University Hospital, Rigshospitalet. Senate member (1995) • Pfizer, KIMS International Board. Member (1994 - present) • Community Bureau of Reference (BCR), European Union Member (1987 - 1995); Leader of project concerning preparation and stability of thyroglobulin reference material for use in

3 immunoassays. Resulted in CRM457 used globally for Tg assays and 2 very large detailed reports in ABC 1996. • Member of the Danish pituitary coordination group (1991-1996) • Member of working group, DSIM, recommendations for thyroid diagnosis and treatment (1993) • Medlem af arbejdsgruppe under dansk kirurgisk selskab vedrørende udarbejdelse af forslag om thyreoideakirurgiens strukturering og visitationsforhold i Danmark (1991) • Collaboration Committee, Dep Med, Gentofte University Hospital (1987- 1990) • Community Bureau of Reference, BCR, EU. Director (1986-1994) • Board of Safety and Department leader, Frederiksberg Universitet Hosp. (1983-1986) • Consultant at Autoimmune Laboratory, State Serum Institute on Autoimmune Thyroid Analyses. (1985-1990) • Board of Young Physicians (Reservelægerådsformand), Herlev University Hospital. Director (1981-1982) • Board of Acute Medical Admissions, Herlev University Hospital. Member (1979-1982) • Member of EORTC Thyroid Study Group on EU standardisation and collaboration on thyroid cancer (1980-1993) • Member of Project Group on planning of new Medicine Building, Frederiksberg Hospital (1984-1986) • Consultant and reagent provider for Serum Thyroglobulin assay at Finsen Institute (1984- 1990) • §9 Course on Safety (1984) • Clinical Biochemical collaboration between Departments, Odense University Hospital. Member (1977-1978)

Teaching

Apart from the activities mentioned below, I have during all the years been planning and teaching at numerous pre- and postgraduate courses both nationally and internationally. I have planned and conducted examinations for the medical students at KU 4 times per year. Over the years I have also been tutor for many visiting medical students and young doctors in specialist training from abroad, approx 2-6 per year

• Adjungated Professor, Medical School, Messina University, Italy • Tutor for pregraduate medical student Anneke Stallman from Freiburg Germany (2005) • Copenhagen University. Member of Det Sundhedsvidenskabelige Fakultets eksamensankenævn (2001) • Lecturer at Folkeuniversitetet RUC: Autoimmunity in organs. (1998) • Lecturer at Folkeuniversitetet; “Autoimmuny in organs”. (1997) • Member of Theme for Endocrinology under 7.-10. semester teaching board (1997) • Member of 10. semesterudvalg in Medicine on behalf of Institute for Internal Medicine (1996) • Tutor, 2 weeks laboratory training for Ph.D. student Valérie Éstienne, Marseille, France (1997) • Laboratory of Endocrinology and Molecular Biology, Frederico II University, Naples, Italy (1996-1996) Visiting professor (1996-1996) • Organiser and teacher at Medical Faculty, Bucharest, Romania Senate member (1993) • Tutor, 2 weeks laboratory training for Ph.D. student Martha Channing, Amsterdam, Netherlands (1997) • Committee of Postgraduate medical Education (Lægelige uddannelsesudvalg), Herlev University Hospital (University / College). Member (1989-1990)

4 • Copenhagen University, Faculty of Health Sciences. Clinical Teacher in Internal Medicine (1987-1990) • Postgraduat tutor dept of medicine F, KAS Gentofte (1987) • Member of course organisation in Danish Thyroid Association (1986-1996) • Lecturer at Folkeuniversitet: Goitre and autoimmune diseases (1986) • Copenhagen University. Lecturer in Clinical Medicine (1984-1986) • Exam Scient, Odense University Lecturer in Clinical Medicine (1976-1976) • Odense University Hospital. Teacher at Exam Scient Education (1975-1976)

Scientific Associations Membership

• American Thyroid Association Membership from 1995 – present; Nomination Board member (2007- 2012); Public Health Board from 2012-present • Danish Society for Internal Medicine Membership from 1985 – present • Danish Endocrine Society Membership from 1985 – present; Board member from 1994- 2000 • Danish Thyroid Association Membership from 1985; Co-founder and Secretary-Treasurer (1985-1992); member of Educational Board (1990-1996) • Endocrine Society Membership from 1997 – present. Member of Subcommittee: Clinical Guidelines Task Force Group (2017- present) • EORTC Thyroid Study Group Membership from 1981 to 2002 (group dissolved); Secretary- Treasurer (1986-1992); Board member (1992-2002); President of subgroup committee (1984-1996); • European Neuroendocrine Association Membership from 1993 – present • European Society for Endocrinology Membership from 2005 – present; Nomination Board Member (2009-2014) • European Thyroid Association Membership from 1983 – present; Board member (1989- 1993) and (2002-2008); Secretary (2002-2008); Treasurer (2002-2008); Member of subgroup committees (ETA Educational Board (2002-2008); Public Relation Board (2002- 2008); Public Health Board and Archives Board (2002- present); member of Standardisation Working Group (2002- present) • European Thyroid Association Cancer Network (ETACRN) Membership and Board member (2002 – present); secretary (2004-2008); President (2008-2012) • Growth Hormone Research Society Membership from 1993 – present

Editorial Board Memberships

• Editorial Advisor 'The Medicine group', Oxford Publishers (1986-1990) • Autoimmunity. Section Editor (1989-1999) • Thyroid Research. Member of the Editorial Board (2007-present) • Acta Endocrinologica. Member of the Editorial Board (1983-1989) • Faculty of 1000 Medicine. Member of the Editorial Board (2005-present) • Life Science Advances. Experimental and Clinical Endocrinology: A Journal of The Council of Scientific Research Integration. Member of the Editorial Board (1986-1996) • Ugeskrift For Laeger. Member of the Editorial Board (1995-2005) • European Journal of Internal Medicine. Section Editor (2007-2018) • Hormone Research Member of the Editorial Board (2004-present) • European Journal of Endocrinology Member of the Editorial Board (2002-2007) • Journal of Clinical Endocrinology and Metabolism Member of the Editorial Board (2008- 2013)

5 • Endocrine (2009-2019) • European Thyroid Journal. Member of the Editorial Board (2012-2019) • Editor of ‘Encyclopedia of Endocrine Diseases 2nd Ed, Thyroid section’, Elsevier, Oxford 2017 • Editor of ‘Medicin’ 1st Ed 2013 – FADL’s publisher – main textbook of Medicine for Danish Medical Students • Editor of ‘Medicin’ 2nd Ed 2015 – FADL’s publisher – main textbook of Medicine for Danish Medical Students • Editor of ‘Medicin’ 3rd Ed 2018 – FADL’s publisher – main textbook of Medicine for Danish Medical Students

Medals and Diplomas

• Who is Who professionals - outstanding scientific achievement - diploma 2008, 2009 and 2012. • Awarded by UEMS: Department of Excellence in Medical Endocrinology and Metabolism - distinction 2007 • Member of Index Copernicus Scientists 2007 • Awarded by Dagens Medicin: Best Department in Denmark in Medical Endocrinology and metabolism • European Thyroid Association Excellent organization achievement 2008 • Haines Lecturer’s Award, Mayo Clinic, Rochester, Minnesota, USA • Hagedorn Prize, Danish Society for International Medicine 2011 • The ETA Pinchera Award for Research Achievement 2016 • Nominated by very distinguished American colleagues for the ATA Paul Starr Award 2019 • Minerva Foundation's Bror-Axel Lamberg Prize in Endocrinology, Finnish Endocrine Society 2019

Other activities

Peer reviewed work – grant proposals

• Ethics Committee Applications (Committee A), approx. 100 per year. 2004-present • Application for funding from the Danish Council for Independent Research (FSS) 2014 • Cancer Research UK. Funding Scheme: Science Committee - Biomarker Project Award Application Title: A novel genetic variant predisposing to goitre and progression to papillary thyroid cancer. A potential biomarker? Application Reference:C49718/A17299. 2013 • Grant application for the Rational Pharmacotherapy Program. zonmw, The Hague, Netherlands 2012 • Research fellows, Rigshospitalet. 65 research grant applications. 2009. • Review Board Meeting of the BMBF funding initiative “Rare disease research consortia” (June 27th/28th 2011, Berlin). • National Research Council (FSS) Research applications in clinical and basic medical research: 745 grant applications: 2009. • Research fellows, Rigshospitalet. 51 grant applications. 2009. • National Strategic Research within Clinical Research. Authors: 116 grant proposals. Date: 2009-05-25 • National Research Council (FSS). Authors: Approx 250 grant proposals for post doc positions and other. Date: 2009-05-14 • National Research Council (FSS) Research applications in clinical and basic medical research: 663 grant applications: 2008. • Strategic research programme in Clinical Research: 45 research grant Applications. 2008.

6 • Strategic research Programme on alternatives to animal research: 15 grant applications. 2008. • Strategic research programme on female research leaders. 96 research grant applications. 2008. • National Research Council (FSS): applications in clinical and basic medical research 250 grant applications. 2008. • Research fellows, Rigshospitalet. 43 grant applications. 2008. • GENOPAT programme, Paris, France: IUGR and PPAR-gamma. Blanchon Loic. 2008. • Grant proposal GENOPAT Paris, France: in the development of aTR aprogramme: Role of the Thyroid Hormone Receptor atherosclerosis. Jacques Samarut. 2008. • Grant proposal : GENOPAT s expression and function(s) through epigeneticaprogramme, Paris, France: Discovery of the XL and genetic causes of pseudohypoparathyroidism Authors: Agnes Linglart. Date: 2008-05-29. • Research fellows, Rigshospitalet. 87 research grant applications. 2007. • National Research Council (FSS): applications in clinical and basic medical research. 653 research grant applications. 2007. • National Research Council (FSS): Research applications in clinical and basic medical research. 356 grant applications. 2007. • Research fellows, Rigshospitalet. 79 research grant applications. 2006. • National Research Council (FSS): Research applications in clinical and basic medical research. 674 grant applications. 2006. • National Research Council (FSS): Research applications in clinical and basic medical research. 265 grant applications. 2006. • Research fellows, Rigshospitalet. 94 research grant applications. 2005. • National Research Council (FSS): Research applications in clinical and basic medical research. 663 grant applications. 2005. • National Research Council (FSS): Research applications in clinical and basic medical research. 246 grant applications. 2005. • The Velux Foundation, Grant application for osteoporosis. Kim Brixen. Date: 2005-03-01 • Research fellows, Rigshospitalet. 78 research applications. 2004. • Research Fellows, Rigshospitalet. 89 research grant applications. Date: 2003-12-12 • Research fellows, Rigshospitalet. 84 research grant applications. Date: 2003-12-11 • Research fellows, Rigshospitalet. 96 research applications. 2002. • Research fellows, Rigshospitalet. 93 research grant applications. 2001. • PhD grant proposal, Odense University. 2 grant applications in clinical endocrinology. Date: 2001-01-09 • Research fellows, Rigshospitalet. 87 research grant applications. 2000. • Research fellows, Rigshospitalet. 85 research grant applications. 1999. • Research fellows, Rigshospitalet. 75 research grant applications. 1998. • EU research programme. 47 research grant proposals. 1998. • Research fellows, Rigshospitalet. 65 research grant applications. 1997. • PhD grant proposal, Odense University. 3 grant applications in clinical endocrinology. 1997. • EU research programme. 55 grant applications. 1997. • Research Fellows Rigshospitalet. 56 research applications. 1996. • EU Research Programme. 56 Research grant applications. 1996. • The Wellcome Trust, UK - grant application on thyroid, iodine and breast cancer. Peter Smyth. 1996. • Grant proposals Thyroid Autoimmunity. Several applications. 1996. • Research fellows. Rigshospitalet. 36 grant applications. 1995. • EU Research programme. 25 research grant applications.1995. • EU research programme. 65 grant proposals in Clinical Biochemistry. 1994. • Research fellows. Rigshospitalet. 35 grant proposals. 1994. • Research fellows. Rigshospitalet. 44 grant applications. 1993.

7 • EU research programme. Approx 45 grant proposals. 1993. • EU Brussels research programme. Approx 50 grant applications. 1992. • Research positions as fellows. Rigshospitalet. Approx 50 grant applications. 1991.

Peer reviewed work – dissertations

• DMSc- Long-term consequences of previously treated hyperthyroidism. Essi Ryödi, Tampere Finland (2019) • PhD – “The impact of Levothyroxine Treatment on Cardiovascular Risk and Mortality in Patients with Thyroid Dysfonction” Mette Nygaard Einfeldt (2018) • DMSc – “ Serum and dried blood spot thyroglobulin as a novel biomarker of iodine status in pregnancy” Sara Stinca, ETH Zürich (2016) • DMSc - Type 1 diabetes; immunogenetics and association to thyroid autoimmunity in Children” Berglind Jonsdottir Malmö-Lund University (2016) • DMSc - ”Endocrine and metabolic characteristics in polycystic ovary syndrome” Dorte Glintborg, University of Southern Denmark (2015) • DMSc: ”Hypothyroidism and pregnancy” Michaela Granfors (2015) • PhD: ”Subclinical hypothyrodism and pregnancy. Relation to adverse outcome and mitochondrial dysfunction” Anne-Dorthe Feldthusen, Copenhagen University (2014) • PhD: “Characterisation of human Leydig cells During development and in patients with reproductive disorders” Grete Lottrup (2013) • DMSc: “Epithelial Mesechymal Transition in Somatotroph Pituitary Adenomas” Tove Levka. The Faculty of Medicine University of Oslo. (2013) • DMSc:"Thyroid autoimmunity and thyroid dysfunction in Denmark. On the importance of iodine intake and other risk factors" Inge Bülow (2012) Aarhus University. • PhD: “Environmental Endocrine Disrupters and Adult Testicular Function”: Ulla Nordström Joensen, KU (2012) • PhD: ”Adrenal Function in Danish Children: Importance of Environmental and Genetic Factors”: Annette Moritsen, KU (2012) • PhD: “Aspects of the natural history of acute lymphoblatic leukaemia – the adrenal hypothesis”: Therese Risom Vestergaard, KU (2012) • DMSc: ”The genetic background of gestational diabetes mellitus” Anastasia Papadoulow (2011) Malmö-Lund University • PhD - "H2O2 and NO influence TEC Viability and Differentiated Function" Nadia Lander Landex (2010) • PhD: Substrate and energy metabolism in patients with hypothyroidism – interaction with body composition and insulin sensitivity. Signe Gjedde, Århus Universitet Oktober 2009 • PhD: Metabolic and morphologic abnormalities in HIV infection and growth hormone as a therapeutic option. Birgitte Rønde Hansen, KU. 2009. • DMSc: Aspects of diagnosis and treatment of hypopituitarism in adult life. Helena Filipsson. 2009, Göteborg, Sweden • PhD: Clinical Aspects of ghrelin: Pharmacokinetic and metabolic effects. Esben Thyssen Vestergaard. Date: 2008-04-16. Aarhus • PhD: Testicular dysgenesis syndrome (TDS). Authors: Rikke Raagard Sørensen, KU. Date: 2007-11-30 • DMSc: Physiology and pathophysiology of growth hormone binding protein: methodological and clinical aspects. Authors: Sanne Fisker, Aarhus University. Date: 2007-08-26 • DMSc: Sphingolipid signalling in normal and malignant thyroid cells. Sonja Balthasar, Sweden. 2006. • DMSc: Risk factors for benign thyroid disease. Nils Knudsen. 2005.

8 • DMSc: Short-range intercellular calcium signalling in bone. Niklas Rye Jorgensen. 2005. • PhD: Insulin-like growth factor I (IGF-I), IGF-I binding proteins and collagen synthesis – relation to mechanical loading of tendon. Jens Lykkegaard Olesen: 2005. • PhD: Fuel metabolism and muscle protein kinetics in hyperthyroidism. Authors: Anne Lene Dalkjaer Riis. 2003. • PhD: Regional variations in goitre prevalence in Denmark – and the impact of tobacco smoking. Nils Knudsen. 2001. • PhD: Ultrasound and ultrasound-guided biopsy in the diagnosis of thyroid cancer. Michel Court-Payen: 2000 • DMSc: 131-Iodine treatment of benign thyroid disease. Birte Nygaard: 2000. • DMSc: Observer variation in the diagnosis of thyroid disorders: criteria and impact on diagnostic decision-making Anne Jarløv. 2000. • DMSc: Clinical Pathological Aspects of Hypothyroidism and Lymphocytic Thyroiditis in Dogs. Lars Iversen: Dr. med. Vet, Copenhagen university. 1999. • Master degree: Non-toxic goitre. Mubeena Aziz. 1999. • PhD: Jørgen Hangaard: Betydning af cortisol og endogene opoider for sekretion af adrenocorticotropin, thyrotropin, prolactin og luteiniserende hormone. Jørgen Hangaard: Betydning af cortisol og endogene opoider for sekretion af adrenocorticotropin, thyrotropin, prolactin og luteiniserende hormone. 1999. • DMSc: On polyglandular autoimmune (PGA) syndromes and association to sarcoidosis. Konstantinos I. Papadopoulos, Lund University, Sweden. 1999. • PhD: Gonadal function in patients with testicular germ cell neoplasia. Peter Meidahl Petersen: 1999. • PhD: Growth hormone secretion capacity in adults with pituitary disease and control subjects. Hans Christian Hoeck. 1998. • PhD: Type 2 diabetes. Pernille Vedel. 1998. • PhD: Investigations into the presence and influence of thyroid associated factors in the natural history of breast disease. Mark T. Kilbane, Dublin University, Ireland: 1998. • PhD: Antistofdannelse mod somatostatinanalogen oktreotid efter nasal, subkutan og intramuskulær applikation hos patienter med akromegali og karcinoidt syndrom. Andreas Kaal: Aarhus University. 1997. • Master degree: Sex hormone level in males referred for infertility. Ahmad M Issa. 1997. • PhD: A model for the study of protein expression in transplanted islets of Langerhans during development of diabetes in BB-DP rats. Ulla Bjerre Christensen: 1997. • Master degree: Clinical non-secreting pituitary adenoma - a retrospective and follow-up study: Helle Lund. 1996. • DMSc: Glucose-6-Phosphate dehydrogenase (G6PD) activity as an index of thyroidal stimulation and superoxide metabolism in thyroid cancer. David J. Conway, Dublin, Ireland. 1996. • PhD: Measurement of urinary growth hormone excretion: Methodological aspects and reference values. Katharina Main: 1995. • PhD: Livsstil, sociologiske og fysiologiske forhold hos københavnske kvinder, der ønsker østrogensubstitution efter menopausen, Lars Bjørn Jensen: 1995. • DMSc: Methods for measurement of TRH and clinical application. Johan Iversen 1994.

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Peer reviewer work – other

Since 1996 reviewer of 37 positions as chief physician at different departments (e.g. Endocrine surgery, Gynaecology, Urology, Growth of Reproduction, Medical Endocrinology) at Rigshospitalet, Odense and Hvidovre Hospitals, as well as Steno Diabetes Center.

• ECE abstract reviewer 2020 • ENDO abstract reviewer 2020 • ECE abstract reviewer 2019 • ENDO abstract reviewer 2019 • Presidential Poster Judge – Endo2019 • Chief Position Steno Diabetes Center Copenhagen – Review Committee (2019) • ECE abstract reviewer 2018 • ENDO abstract reviewer 2018 • ECE abstract reviewer 2017 • ENDO abstract reviewer 2017 • Presidential Poster Judge – Endo2017 • Review committee for Speakers competition at Rigshospitalet for young researchers (FYF) (2017) • Search Committee Clinical Professorship, Diabetes, Copenhagen University (2016) • ECE abstract reviewer 2016 • ENDO abstract reviewer 2016 • Programme Chair for Research, Review Committee Århus University (2015) • Poster chair on the PhD Day, Faculty of Health KU 2013 Reviewer Committee for Speaker competition at Rigshospitalet for young researchers (FYF) 2010, 2013, 2015 • ECE abstract reviewer 2015 • Clinical professorchip Institut for Regional Sundhedsforskning, Det Sundhedsvidenskabelige Fakultet, Syddansk Universitet og ved Medicinsk afdeling, Sygehus Lillebælt, Forskningsenheden, Endokrinologisk afsnit, Fredericia og Kolding Sygehuse • ENDO abstract reviewer 2014 • ICE/ENDO abstract reviewer 2014 • Associale professorship with research activity in medical endocrinology at the Institut for Regional Health Research 2013 • ENDO abstract reviewer 2013 • Clinical professorship in Medical Endocrinology, Faculty of Heath, University of Southern Denmark 2012 • Member of committee at Leiden University Medical Center (LUMC) to advise the Board on the establishment of a chair in Clinical Endocrinology and Metabolism (a tenured faculty position as full Professor) at the department of Endocrinology and Metabolism of the LUMC. Candidate is Alberto M. Pereira, MD, PhD, of the department of Endocrinology and Metabolism 2011 • Honorary Professor in Environmental aspects of male reproduction. Professor Jorma Toppari. Faculty of Health, KU 2011 • Professorship Peter Smyth, PhD, Trinity College, University of Dublin, Ireland (2010) • Professorship Corin BADIU MD, PhD. Institute of Endocrinology. "C. Davila" University of Medicine and Pharmacy. Bucharest, Romania (2010)

10 • Associate professorship at LIFE, Copenhagen University (2009) • Professorship: Positions as Professor at Sahlgrenska University, Götheborg, Sweden. 1 Application for Internal medicine and Medical Endocrinology (2009) • Chairman of review committee for Speakers competition at Rigshospitalet for young researchers (FYF) (2009) • European Journal of Endocrinology Prize 2009, Wiebke Arlt; Francesca Carlomagno, Simon Pierce, Manuel Tena-Sempere (2009) • Professorship: Positions as Associate Professor at Copenhagen University. 2 Applications for Internal medicine (2006) • Professorship Candidate for Readership, Queen Mary University of London, UK. Dr. William Drake (2006) • Clinical Associate professorship, Copenhagen University. 2 applications for Internal medicine (2004) • Professorship: Neuroendocrinology: Ulrich Knigge, Philip Just Larsen, Andreas Kjær + 2 more (2002) • Professorship: Thyroid and iodine. Peter Smyth, Dublin, Ireland (2002) • Chairman of review committee for Speakers competition at Rigshospitalet for young researchers (FYF) (1999) • Specialist assessment for the Court of Oslo (Byret) concerning possible malpractice for acromegaly at Rikshospitalet, Oslo, Norge (2000)

Mentor of Scientific Dissertations Postgraduate

• PhD – Optic imaging to identify parathyroid glands and preserving their function during total thyroidectomy “ Eva Lykke (Ongoing) • PhD – “Hypothalamic Function in Energy Metabolism with Emphasis on the Ghrelin System in Primary Human Somatotropic Cell Cultures, in Human Physiological Studies and in a Double-Blind, Randomized, Controlled Trial of the Safety and Efficacy of Tesofensine with Metoprolol in Patients with Hypothalamic Obesity” Sarah Byberg (Ongoing) • PhD - "Udvikling og videnskabelig undersøgelse af multipel momentan måling af helbredsrelateret livskvalitet" Victor Brun Boesen (Ongoing) • PhD – “Forskelle i glukokortikoid-induceret binyrebarkinsufficiens hos patienter med rheumatoid arthritis som følge af polymorfier i glukokortikoid receptor genet med forskellig glukokortikoid sensitivitet” Stina Borresen (2020) • PhD – “Gravide danske kvinders thyroideafunktion efter tilsætning af jod til salt i DK” Sofie Bliddal Mortensen (Ongoing) • PhD – ”Sleep and circadian rhythms in children with brain tumours” Line Pickering (ongoing) • PhD - “Medullary thyroid carcinoma in Denmark 1997-2014: A national study of epidemiology, prognosis and heredity” Jess Sloth Mathiesen (2018) • PhD – “Exposures and possible endocrine disrupting effects of UV filters on human health.” Mariana Krause (2018) • DSc – “Development, validation, abbreviation and appli-cation of an international thyroid- related quality of life patient-reported out-come measure” Torquil Watt (2017) • PhD – “Quality of life in patients with non-toxic goiter or hyperthyroidism. Disease impact, treatment effects and clinical trial preparation” Per Cramon (2017) • PhD – “Visual outcome, pituitary function, cerebrovascular incidents and tumor control after fractionated stereotactic radiation therapy of benign anterior skull base tumors” Arnar Astradsson (2016)

11 • PhD – “On the clinical relevance of selenium supplementation for thyroid function and thyroid-related quality of life in chronic autoimmune thyroiditis” Kristian Hillert Winther Odense University (2016) • PhD – “Acromegaly: epidemiological and experimental aspect” Jakob Dal (2015) • PhD – ”The influence of phthalates on immune cell responses and thyroid cell function” Juliana Frohnert (2015) • DSc – “Traumatic brain injury and hypopituitarism” Marianne Klose (2015) • PhD – “Development, validation and application of an international thyroid-related quality of life patient-reported outcome, ThyPRO” Torquil Watt (2015) • PhD - Thyroid function in pregnant women and in children: Associations with growth and phthalate exposure. Malene Boas, KU (2010) • PhD - "Development of a Danish thyroid-specific quality of life questionnaire". Torquil Watt (2009) • PhD - "hypopituitarism after TBI": Marianne Klose (2007) • DSc - "Endocrinological late effects following radiotherapy and chemotherapy of childhood brain tumours (disputats). København: Lægeforeningens Forlag; 2005:1- 20. ": Marianne Schmiegelow (2005) • PhD - "The influence of iodine and tri-iodo-thyronine on autoimmune thyroiditis and type 1 diabetes mellitus in rats and application of stereological tools to the thyroid gland of rats: Own Publisher; 2005:1-83": Marie-Louise Hartoft-Nielsen (2005) • PhD - "Contrast enhanced Doppler ultrasound: methodological and clinical studies on tumour vascularity": Nanna Bang (2005) • PhD - "Investigation and treatment of obesity in hypopituitary patients with growth hormone deficiency. Own Publisher 2004; 1-76": Henriette Mersebach (2004) • PhD - "Childhood onset growth hormone deficiency in adults - aspects on diagnosis and consequences. Own Publisher; 2004: 1-119.": Martin Lange (2004) • PhD - "Cognitive performance, psychiatric symptoms, and healt related quality of life in patients with Graves' disease. Clinical and MR spectroscopic abnormalities. Own Publisher; 2004: 1-41": Tina Elberling (2004) • PhD - "Microalbuminuria and metabolic control as predictors of complications in pregnancy in women with type I diabetes. København: Own publisher; 2003: 1- 70. ": Pia Ekbom (2003) • DSc - "Pituitary hormone replacement in patients with hypopituitarism" : Erika Hubina (2001) • DSc - "cytokines and thyroid cells": Åse Krogh Rasmussen (1998) • PhD - "Prospective evaluation of patients with Graves' disease. Measurement of TSH receptor autoantibodies, body composition, serum leptin and serum proteins. own Publisher. 1999" : Tina Zimmermann Belsing (1998) • PhD - "Growth hormone treatment in growth hormone deficient adults - an 18 months randomised placebo controlled double blinded study of sweat secreation, bones and heart. own Publisher. 1998": Simone Bjerregaard Sneppen (1998) • PhD - "Growth hormone secretion capacity in adults with pituitary disease and control subjects. Own Publisher 1997": Hans Christian Hoeck (1997) • PhD - "diabetes type 2": Pernille Vedel Jepsen (1996)

Pregraduate

• Master degree and Research Year Student - Double-Blind, Randomized, Controlled Trial of the Safety and Efficacy of Tesofensine with Metoprolol in Patients with Hypothalamic Obesity” Kim Huynh (ongoing)

12 • Bachelor Degree – “Iodine intake and its effect on gl thyroidea and the body” Freja Lähteenmäki (2020) • Bachelor degree – “Development of permanent hypothyroid dysfunction after postpartum thyroiditis” Stine Bybjerg (2020) • Master degree and Research Year Student - The prevalence of adrenal insufficiency in patients with asthma receiving inhaled corticosteroid treatment: A systematic review and a meta-analysis of RCT and observational studies” Louise Skovbjerg (2019) • Master degree and Research Year Student – “impaired hearing during treatment of Fabry disease” Puriya Daniel Yazdanfard (Ongoing) • Master degree and Research Year Student- “Influence of the suspected endocrine disruptor, Triclosan, on Cytokine Production by human Immune Cells” Mai Homburg (2019) • Bachelor degree- ” Hippocampal volume, depression, anxiety and quality of life in patients with Cushing’s syndrome. A systematic review and meta-analysis of observational studies” Emilie Frimodt Møller (2018) • Bachelor degree- ”Clinical characteristics and metabolic profile in four MDPL-patients with the inheritable c.1519C>T variant in POLD1” Sara Sakjah (2018) • Bachelor degree- ”Immunopatogenesen af Graves’ oftalmopati – Et litteraturstudie” Anja Skov (2018) • Bachelor degree- ”Genetik af polyglandulær autoimmun syndrom type 2" Elvira Silajdzija (2018) • Bachelor degree- “The role of B cells in Graves disease” Emil Anton Frandsen (2018) • Bachelor degree- “Antithyriod antibodies and recurrent pregnancy loss; thyroideaantistoffer og gentagne spontane aborter” Elisabeth Waldemar Jacobsen (2018) • Master degree and Research Year Student – “Genotype-phenotype associations in a Danish cohort of 44 patients with SDHX variants” Ailsa Maria Main (2018) • Master degree and Research Year Student- “High prevalence of suppressed adrenal cortical function in kidney transplanted patients during low-dose prednisolone therapy” Amalie Valentin (2018) • Bachelor degree- “Hearing Loss in Fabry Disease. Study of the Danish Nationwide Cohort at baseline before commencement of Enzyme Replacement Therapy” Puriya Daniel Yazdanfard (2018) • Master degree- “Thyroid abscess in a young woman with a nodular Goitre: Case report and review af the literature” Agnes Linge Montelius (2017) • Bachelor degree- “Fæokromocytom – et litteraturstudie af prædiktive værdier af PASS og Ki67 I klinisk malignitetsvurdering af patienter med fæokromocytom” Sarah Forslund Jacobsen (2017) • Bachelor degree- ”Generelle principper i den endokrine behandling til transkønnede” Alex Thomsen (2016) • Master degree- “Adrenal insufficiency in Asthma patients treated with inhalation-steroids” Helin Shebab (2016) • Master degree- “Fractionated stereotactic radiation therapy in the treatment of acromegaly – long term follow-up” Emil Hansen Møller (2016) • Bachelor degree- “Risk of recurrent pregnancy loss in thyroglobulin antibody positive women” Anna Nicoline Wolfhagen Thusholt (2016) • Master degree- ”Effect of growth hormone deficiency and its replacement on the heart” Sissela Elisabet Kristin Skoglund (2015) • Master degree and Research Year Student. ”Modified release compared to conventional hydrokortisone on diurnal fatigue in secondary hypoadrenalism (PlenadrEMA)” Thea Christoffersen (2015) • Bachelor degree- “Cushing’s disease – Behandling og prognose”. Amir Almatlouh (2015)

13 • Master degree- ”Retrospektivt follow-up studium af danske MEN2A-patienter” Ditte Hansen (2015) • Master degree and research year student – “Samspil mellem thyroida autoimmunitet og hormonforstyrrende stoffer” Thit Mynster Kronborg (2015) • Master degree. Stimulated free salivary cortisol correlates with body composition markers of fat mass in healthy non-obese men and women. Flemming Karlsen (2015) • Master degree- ”Pituitary axes and body composition after SAH” Zainab Gassem Nagras (2015) • Master degree- ”Metabolic and Behavioural Effects of Developmental Hypothyroxinemia” Louise Ramhøj DTU, KU (2014) • Bachelor degree- “Ghrelin og thyreoideahormon”. Maria Barington (2014) • Bachelor degree- “Thyroidea autoimmunitet blandt infertile kvinder” Maria Christine van der Klein (2014) • Bachelor degree- “Neuroudviklingsmæssige konsekvenser af maternel hypothyroidisme” Amalie Grue Valentin (2014) • Master degree and research year student. “Why glucocorticoid withdrawal may sometimes be as dangerous as the treatment itself”. Stina Dinsen (2014) • Master degree- ”Effekt af enzymsubstitutionsbehandling på hjertepåvirkning hos patienter med Fabry sygdom”, Christoffer Valdorf Madsen (2014) • Bachelor degree- ”Hypothyroidisme og kapacitet for motion” Tanja Lundholm Rasmussen (2014) • Master degree and research year student. ”Gravide danske kvinders thyroideafunktion efter tilsætning af jod til salt i DK” Sofie Bliddal Mortensen (2013) • Master degree and research year student - ”Prognostic value of pituitary histopathology and plasma hyperprolactinaemia in predicting the risk of glucose metabolic disturbances in patients with acromegaly” Trine Møller Erichsen (2013) • Bachelor degree- “Cushing’s syndrom – med fokus på diagnose og diagnostisk metoder”. Helin Shebab (2013) • Master degree - “Subclinical Hypothyroidism is a common finding in Patients with Cyanotic Congenital Heart Disease” Peter Bak (2013) • Master degree - “A/H1N1 antibodies in type 1 diabetes children diagnosed before, during and after the Swedish Pandemrix® vaccination campaign 2009-2010” Matilda Svensson (2013) • Bachelor degree- ”Thyroglobulin, genfindingstest og anti-Tg måt på BRAHMS kryptor” Grethe Holt Overgaard (2013) • Master degree and research year student - ”Indvirkning af serum og ideel tid på måling af thyroglobulin og AMP ekspression fra humane thyroideaceller dyrket i monolag” Emma Sofie Lindström (2012) • Master degree and research year student. ”Kortlægning af søvnmønster og dets mulige association til ødelæggelse af døgn- og søvnregulerende kerner hos patienter med hypothalamisk skade” Line Pickering Jacobsen (2012) • Bachelor degree- ”Hypopituitarism after fractionated stereotactic radiation therapy of anterior skull base meningiomas is caused by mass effects, not radiation” Emil Hansen Møller (2012)

14 • Master degree- ”Primary hyperparathyroidism associated with multiple endocrine neoplasia 1 (MEN-1): review of literature and a case report” Marie Therese Lassen (2012) • Bachelor degree- "Effect of enzyme replacement therapy on the heart evaluated by ECG variables – with main focus on left ventricular hypertrophy". Christoffer Valdorf Madsen (2012) • Master degree- ”A Danish experience: Retrospective follow-up analysis on kidney function in patients with Fabry disease treated with agalsidase-beta” Henrik Granqvist (2012) • Bachelor degree- ”An elucidation of the genetic predispose for the development of Hashimotos thyroiditis and the genes involved” Therese Adrian (2011) • Masterdegree- ”Prædiktorer for ændringer i knoglemineralindhold hos voksne patienter med væksthormoninsufficiens” Oliver Klefter (2011) • Bachelor degree- “The aetiology of Graves’ disease”. Jannie Frimer Nielsen (2010) • Master degree- “Quality of life in thyroid disease”: Per Cramon (2009) • Master degree - "Is stress a contributing factor to the onset of Autoimmune Thyroid Disease?" : Petra Salomonsson (2008) • Master degree - "growth hormone, muscles and bones" : Oliver Klefter (2007) • Master degree - "Glucose metabolism in patients during long-term treatment of acromegaly" Jakob Bennike (2006) • Master degree - "Hypothyropidism and Treatment" : Dorte Merete Moesby (2006) • Master degree - "thyroid hormone measurements" : Dorte Hansen (2006) • Master degree - "Growth hormone deficiency and body composition" : Søren Rasmussen (2004) • Master degree - "Growth Hormone and the effect of growth Hormone Deficiency on body composition and bones in adults" : Abdul Noor Qadir (2002) • Master degree - "Diagnosing acromegaly. Biochemical assessment and the possible use of sinus petrosus inferior catherisation": Michael Moller (2002) • Master degree - "culturing of thyroid cells": Julie Bay (2001) • Master degree - "Thyroid hormone in non-thyroidal illness": Søs Wollesen (1999) • Master degree - "Assessment of the clinical usefulness of TSH assays in the diagnosis of thyrotoxicosis": Henriette Mersebach (1998) • Master degree - "Thyroid animal models": Marie-Louise Hartoft-Nielsen (1997) • Master degree - "Is there a relationship between hyperinsulinism and cardiovascular disease?": Lars Burchardt (1995) • Master degree - "Thyroid and Acromegaly" Susanne Scherer (1994) • Master degree - "Influence of growth Hormone Deficiency in adults on different organ systems": Abdul Latif Chaudhary and Ali MR Baroon (1993) • Master degree - "Characterisation of FRTL-5 cells": Tina Zimmermann-Belsing (1993) • Master degree - "Thyroglobulin and Thyroid Surgery": Ulrik Andersen (1985) • Master degree - "Thyroglobulin and thyroid surgery": Aase krogh rasmussen (1985)

Journals’ Reviewer

I have been regular reviewer for many international journals of approx 5-10 manuscripts per month. Below some examples

• Frontiers in Endocrinology (2010- ) • Clinical Thyroidology (2016-) • European Thyroid Journal (2011-)

15 • Endocrine (2010-) • Thyroid Research (2010-) • Journal of Andrology (2009- ) • Bentham Science E-Books (2009-) • Journal of Postgraduate Medicine. (2008-) • European Journal of Ultrasound (2008-) • European Journal of Obstetrics and Gynecology. (2008-) • Protein & Peptide Letters (2007-) • Obesity Reviews: An official journal of the international association for the study of obesity (1999-) • Clinical Chemistry (1997-) • Journal of Molecular Endocrinology (1997-) • Thyroid (1996-) • Hormone And Metabolic Research (1996-) • Clinical Endocrinology (1996-) • Pharmacology and Toxicology (1996-) • Apmis (1996-) • Acta Obstetrica Et Gynaecologica Scandinavica (1996-2005) • Clinical Genetics (1995-) • Endocrinology (1994-) • European Journal of Endocrinology (1990-) • Scandinavian Journal of Immunology (1988-) • Journal of Clinical Endocrinology and Metabolism (1987-) • Autoimmunity (1986-) • Scandinavian Journal of Clinical and Laboratory Investigation (1985-) • Ugeskrift for Læger (1984-) • Journal of Endocrinological Investigation (1982-) • Acta Endocrinologica (1982-1990)

Meetings and conferences

I have been giving more than 1000 oral and poster presentations at international meetings, and I have given invited lectures at international scientific meetings, and universities in e.g. Padova, Pisa, Marseille, Brussels, Stockholm, Nice, Miami, Bucharest, Debrecen, Warsaw, Ljublin, Antwerp, Leipzig, Munich, Los Angeles, Kiev, Tbilisi, Kosice, London, Dublin,Moschow, Athens, Buenos Aires, Gramado (Brazil), Hannover, Paris, Messina, Mayo Clinic, Gothenburg, Oslo, Stockholm, Orlando, San Diego, Prague, Budapest, Barcelona, Naples, Sevilla, Lisbon, Hangzou, Berlin, Catania.

I have furthermore since 1986 participated in the planning of numerous international meetings, symposia, workshops, postgraduate courses, and acted as chairperson on many occasions. Finally, I have been member of several abstract selection committees, poster award committes and other similar activities.

Publications

I have published 446 scientific papers (Scopus)(PubMed: 439)), 56 of which are reviews and 365 original articles. In 66 of these I am first and in 120 last author. In addition, I have written 57 book chapters and 53 other publications listed below. In “Web of Science”, I am registered with 449 publications; H-index = 55 (Scopus).

16 Original Articles

1. U Feldt-Rasmussen Purification of human thyroglobulin for radioimmunoassay and testing by ultracentrifugal analysis and immunoelectrophoresis. J Immunol Methods 1978; 21(3-4):295-303 2. U Feldt-Rasmussen, M Hørder, J Date Forsendelse af blodprøvemateriale fra laegepraksis til et sygehuslaboratorium. I. En spørgeskemaundersøgelse blandt praktiserende laeger i Fyns amt. Ugeskr Laeger 1978; 140(14):810-812 3. U Feldt-Rasmussen, P H Petersen, O S Nielsen. Forsendelse af blodprøvemateriale fra laegepraksis til et sygehuslaboratorium. II. Afprøvning af køletransportkasse. Ugeskr Laeger 1978; 140(14):813-816 4. U Feldt-Rasmussen, P H Petersen, H Nielsen, J Date, C M Madsen Thyroglobulin of varying molecular sizes with different disappearance rates in plasma following subtotal thyroidectomy. Clin Endocrinol (Oxf) 1978; 9(3):205-214 5. U Feldt-Rasmussen, A P Lange, J Date, M K Hansen Effect of clomifene on thyroid function in normal men. Acta Endocrinol (Copenh) 1979; 90(1):43-51 6. U Feldt-Rasmussen, P Hyltoft Petersen, J Date Sex and age correlated reference values of serum thyroglobulin measured by a modified radioimmunoassay. Acta Endocrinol (Copenh) 1979; 90(3):440-450 7. U Feldt-Rasmussen, K Bech, J Date Serum thyroglobulin in patients with toxic and non-toxic goitres compared to sex- and age-matched control subjects. Acta Endocrinol (Copenh) 1979; 91(2):264-270 8. H Nielsen, P H Petersen, U Feldt-Rasmussen, V Binder Variations in plasma protein concentrations in individuals with ulcerative colitis: analytical and biological factors. Scand J Clin Lab Invest 1979; 39(6):495-502 9. U Feldt-Rasmussen, K Bech, J Date, S Thyme, J Hannover Larsen, H Nielsen Anticomplementary activity in diffuse and nodular goiters. Acta Pathol Microbiol Scand [C] 1979; 87(6):365-370 10. J Date, U Feldt-Rasmussen, P H Petersen, K Bech An improved co-precipitation assay for determination of thyroglobulin antibodies. Scand J Clin Lab Invest 1980; 40(1):37-44 11. H Kierkegaard, U Feldt-Rasmussen, M Hørder, H J Andersen, P J Jørgensen Falsely negative urinary leucocyte counts due to delayed examination. Scand J Clin Lab Invest 1980; 40(3):259-261 12. U Feldt-Rasmussen, P Hyltoft Petersen, O Blaabjerg, M Hørder Long-term variability in serum thyroglobulin and thyroid related hormones in healthy subjects. Acta Endocrinol (Copenh) 1980; 95(3):328-334 13. U Feldt-Rasmussen, P H Petersen, J Date Serum thyroglobulin (Tg) in the follow-up of differentiated thyroid cancer after thyroid ablation. Clin Endocrinol (Oxf) 1980; 13(3):303-304 14. H Nielsen, P Olholm, U Feldt-Rasmussen, A Godtfredsen, S E Svehag Circulating immune complexes and complement-fixing antibodies in patients with varicella-zoster infection. Relationship to début of the disease. Scand J Infect Dis 1980; 12(1):21-26 15. U Feldt-Rasmussen, P H Petersen, J Date, C M Madsen Sequential changes in serum thyroglobulin (Tg) and its autoantibodies (TgAb) following subtotal thyroidectomy of patients with preoperatively detectable TgAb. Clin Endocrinol (Oxf) 1980; 12(1):29-38 *Impact factor 2.897 16. J Kvetny, P K Frederikesen, J G Jacobsen, V Haas, U Feldt-Rasmussen, J Date Propranolol in the treatment of thyrotoxicosis. A randomized double-blind study. Acta Med Scand 1981; 209(5):389- 392 17. U Feldt-Rasmussen, A Kemp, K Bech, S N Madsen, J Date Serum thyroglobulin, its autoantibody and thyroid stimulating antibodies in the endocrine exophthalmos. Acta Endocrinol (Copenh) 1981; 96(2):192-198

17 18. U Feldt-Rasmussen, S Husby, O Blåbjerg, J Date, H Nielsen In vitro characterization of synthesized thyroglobulin immune complexes (IC). A model for studies of IC containing an autoantigen. Allergy 1981; 36(2):107-113 19. P Hyltoft Petersen, U Feldt-Rasmussen, M Hørder, O Blaabjerg, K Thygesen Variability of plasma proteins according to molecular size. Long-term and short-term intra-individual variation. Scand J Clin Lab Invest 1981; 41(2):143-150 20. K Bech, U Feldt-Rasmussen, S N Madsen Influence of thyroglobulin on basal and stimulated human thyroid adenylate cyclase activity. J Clin Endocrinol Metab 1981; 53(2):264-269 21. K Bech, U Feldt-Rasmussen, H Bliddal, J Date, M Blichert-Toft The acute changes in thyroid stimulating immunoglobulins, thyroglobulin and thyroglobulin antibodies following subtotal thyroidectomy. Clin Endocrinol (Oxf) 1982; 16(3):235-242 22. U Feldt-Rasmussen, K Bech, J Date, P H Petersen, K Johansen A prospective study of the differential changes in serum thyroglobulin and its autoantibodies during propylthiouracil or radioiodine therapy of patients with Graves' disease. Acta Endocrinol (Copenh) 1982; 99(3):379- 385 23. U Feldt-Rasmussen, K Bech, J Date, P Hyltoft Pedersen, K Johansen, S Nistrup Madsen Thyroid stimulating antibodies, thyroglobulin antibodies and serum proteins during treatment of Graves' disease with radioiodine or propylthiouracil. Allergy 1982; 37(3):161-167 24. U Feldt-Rasmussen, P H Petersen, J Date, C M Madsen Serum thyroglobulin in patients undergoing subtotal thyroidectomy for toxic and nontoxic goiter. J Endocrinol Invest 1982; 5(3):161-164 25. U Feldt-Rasmussen, M Blichert-Toft, C Christiansen, J Date Serum thyroglobulin and its autoantibody following subtotal thyroid resection of Graves' disease. Eur J Clin Invest 1982; 12(3):203-208 26. H Bliddal, K Bech, U Feldt-Rasmussen, M Thomsen, L P Ryder, J M Hansen, K Siersbaek- Nielsen, T Friis Thyroid-stimulating immunoglobulins in Hashimoto's thyroiditis measured by radioreceptor assay and adenylate cyclase stimulation and their relationship to HLA-D alleles. J Clin Endocrinol Metab 1982; 55(5):995-998 27. M Thomsen, L P Ryder, K Bech, H Bliddal, U Feldt-Rasmussen, J Mølholm, E Kappelgaard, H Nielsen, A Svejgaard HLA-D in Hashimoto's thyroiditis. Tissue Antigens 1983; 21(2):173-175 28. S Husby, J Steensgaard, U Feldt-Rasmussen, J Date Molecular distribution of preformed thyroglobulin immune complexes. Immunology 1983; 48(2):401-409 29. U Feldt-Rasmussen, H S Hansen, B Rasmusson Serum-tyreoglobulin-bestemmelse ved differentieret thyreoideakarcinom. En oversigt samt 3 sygehistorier. Ugeskr Laeger 1983; 145(15):1132-1136 30. U Feldt-Rasmussen, I Holten, H S Hansen Influence of thyroid substitution therapy and thyroid autoantibodies on the value of serum thyroglobulin in recurring thyroid cancer. Cancer 1983; 51(12):2240-2244 31. E Kappelgaard, H Nielsen, K Bech, H Bliddal, U Feldt-Rasmussen, M Thomsen Circulating immune complexes in Hashimoto's thyroiditis. Correlation to HLA and autoantibodies. Allergy 1983; 38(6):433-439 32. L Hegedüs, J Kastrup, U Feldt-Rasmussen, P H Petersen Serum thyroglobulin in acute and chronic liver disease. Clin Endocrinol (Oxf) 1983; 19(2):231-237 33. U Feldt-Rasmussen, K Bech, H Bliddal, M Høier-Madsen, F Jørgensen, E Kappelgaard, H Nielsen, J Lanng Nielsen, L P Ryder, M Thomsen Autoantibodies, immune complexes and HLA- D in thyrogastric autoimmunity. Tissue Antigens 1983; 22(5):342-347 34. U Feldt-Rasmussen, H Perrild, K Bech, H Bliddal, J Date, M H Madsen, O Nordfang, L P Ryder, M Thomsen, E Kappelgaard, H Nielsen Discrepancy between haemagglutination and

18 radioimmunological techniques for measurement of serum thyroglobulin autoantibodies. Allergy 1983; 38(1):49-56 35. U Feldt-Rasmussen, L Hegedüs, J M Hansen, H Perrild Relationship between thyroid volume and serum thyroglobulin during long-term suppression with triiodothyronine in patients with diffuse non-toxic goitre. Acta Endocrinol (Copenh) 1984; 105(2):184-189 36. H Perrild, U Feldt-Rasmussen, K Bech, P Ahlgren, J M Hansen The differential diagnostic problems in unilateral euthyroid Graves' ophthalmopathy. Acta Endocrinol (Copenh) 1984; 106(4):471-476 37. M Høier-Madsen, U Feldt-Rasmussen, L Hegedüs, H Perrild, H S Hansen Enzyme-linked immunosorbent assay for determination of thyroglobulin autoantibodies. Comparison with RIA and haemagglutination. Acta Pathol Microbiol Immunol Scand [C] 1984; 92(6):377-382 38. L Hegedüs, S Karstrup, D Veiergang, B Jacobsen, L Skovsted, U Feldt-Rasmussen Cigaretrygning--en vaesentlig årsag til atoksisk struma. Ugeskr Laeger 1985; 147(46):3679-3682 39. L Hegedüs, S Karstrup, D Veiergang, B Jacobsen, L Skovsted, U Feldt-Rasmussen High frequency of goitre in cigarette smokers. Clin Endocrinol (Oxf) 1985; 22(3):287-292 40. J Kastrup, U Feldt-Rasmussen, H R Bartram, J Witten, H Sand Hansen An enzyme linked immunosorbent assay (ELISA) for measurement of human serum thyroglobulin. Evaluation of the influence of thyroglobulin auto-antibodies. Scand J Clin Lab Invest 1985; 45(5):471-476 41. L Hegedüs, J M Hansen, K Lühdorf, H Perrild, U Feldt-Rasmussen, J P Kampmann Increased frequency of goitre in epileptic patients on long-term phenytoin or carbamazepine treatment. Clin Endocrinol (Oxf) 1985; 23(4):423-429 42. U Feldt-Rasmussen, M Høier-Madsen, H S Hansen, M Blichert-Toft Comparison between homogeneous phase radioassay and enzyme-linked immunosorbent assay for measurement of antithyroglobulin antibody content in serum. Relation to presence of thyroglobulin. Acta Pathol Microbiol Immunol Scand [C] 1986; 94(1):33-38 43. B C Kirkegaard, K Bech, C Bregengård, J Faber, U Feldt-Rasmussen Thyreoideastimuleren-de hormon (TSH) i serum som første undersøgelse ved tyreotoksikose. Ugeskr Laeger 1986; 148(15):897-899 44. J Petersen, U Feldt-Rasmussen, M Høier-Madsen, F Larsen, S Husby, K Siersbaek-Nielsen Autoreactive lymphocytes in thyroid disorders. II. Comparison of anti-thyroglobulin antibody production by plaque-forming cell, radio-immunological and enzyme-linked immunosorbent assays. Acta Pathol Microbiol Immunol Scand [C] 1986; 94(3):113-117 45. U Feldt-Rasmussen, M Blichert-Toft, J Date, V Haas Serum thyroglobulin concentration in nontoxic goiter and response to surgery with special reference to risk of goiter relapse. World J Surg 1986; 10(4):566-571 46. J Petersen, U Feldt-Rasmussen, F Larsen, K Siersbaek-Nielsen Autoreactive lymphocytes in thyroid disorders. Quantitation of anti-thyroglobulin antibody formation by a specific haemolytic plaque forming cell (PFC) assay. Acta Endocrinol (Copenh) 1986; 113(1):50-55 47. H Perrild, U Feldt-Rasmussen, L Kayser, J Mølholm Hansen Short-term beta-adrenergic blockade decreases serum thyroglobulin in hyper- and euthyroid patients. J Endocrinol Invest 1986; 9(5):413- 415 48. A K Rasmussen, K Bech, U Feldt-Rasmussen, S Poulsen, K Siersbaek-Nielsen, T Friis, K Bendtzen The influence of interleukin-1 on the function of in vitro cultured human thyroid cells in monolayers. Acta Endocrinol Suppl (Copenh) 1987; 281 93-95 49. L Hegedüs, U Feldt-Rasmussen, J R Andersen, L R Poulsen, J M Hansen Serum thyroglobulin in chronic renal failure--effects of haemodialysis. Scand J Clin Lab Invest 1987; 47(1):35-40 50. S M McLachlan, U Feldt-Rasmussen, E T Young, S L Middleton, M Dlichert-Toft, K Siersbaek- Nielsen, J Date, D Carr, F Clark, B Rees Smith IgG subclass distribution of thyroid autoantibodies:

19 a 'fingerprint' of an individual's response to thyroglobulin and thyroid microsomal antigen. Clin Endocrinol (Oxf) 1987; 26(3):335-346 51. B Rasmusson, U Feldt-Rasmussen, L Hegedüs, H Perrild, K Bech, M Høier-Madsen Thyroid function in patients with breast cancer. Eur J Cancer Clin Oncol 1987; 23(5):553-556 52. H Vagn Nielsen, K Hasselström, U Feldt-Rasmussen, J Mehlsen, K Siersbaek-Nielsen, T Friis, S Haunsø, J Trap-Jensen Increased sympathetic tone in forearm subcutaneous tissue in primary hypothyroidism. Clin Physiol 1987; 7(4):297-302 53. C Kirkegaard, K Bech, H Bliddal, B Danneskiold-Samsoe, U Feldt-Rasmussen Thyroid stimulating antibodies in rheumatoid arthritis: an in vitro phenomenon. J Endocrinol Invest 1987; 10(5):495-498 54. J Date, M Blichert-Toft, U Feldt-Rasmussen, V Haas Lacking evidence for release of thyroid hormones from circulating thyroglobulin during subtotal thyroidectomy. Acta Endocrinol (Copenh) 1988; 117(2):219-224 55. U Feldt-Rasmussen, M Schlumberger European interlaboratory comparison of serum thyroglobulin measurement. J Endocrinol Invest 1988; 11(3):175-181 56. A K Rasmussen, K Bech, U Feldt-Rasmussen, S Poulsen, I Holten, M Ryberg, C A Dinarello, K Siersbaek-Nielsen, T Friis, K Bendtzen Interleukin-1 affects the function of cultured human thyroid cells. Allergy 1988; 43(6):435-441 57. J Friis, T Johnsen, U Feldt-Rasmussen, K Bech, T Friis Thyroid function in patients with Pendred's syndrome. J Endocrinol Invest 1988; 11(2):97-101 58. B K Pedersen, H Perrild, U Feldt-Rasmussen, T Christensen, K Klarlund, J M Hansen Suppressed natural killer cell activity in patients with euthyroid Graves' ophthalmopathy. Autoimmunity 1989; 2(4):291-298 59. N G Rasmussen, P J Hornnes, L Hegedüs, U Feldt-Rasmussen Serum thyroglobulin during the menstrual cycle, during pregnancy, and post partum. Acta Endocrinol (Copenh) 1989; 121(2):168- 173 60. B K Pedersen, U Feldt-Rasmussen, K Bech, H Perrild, K Klarlund, M Høier-Madsen Characterization of the natural killer cell activity in Hashimoto's and Graves' diseases. Allergy 1989; 44(7):477-481 61. T Johnsen, M S Sørensen, U Feldt-Rasmussen, J Friis The variable intrafamiliar expressivity in Pendred's syndrome. Clin Otolaryngol Allied Sci 1989; 14(5):395-399 62. U Feldt-Rasmussen, M Høier-Madsen, N G Rasmussen, L Hegedüs, P Hornnes Anti-thyroid peroxidase antibodies during pregnancy and postpartum. Relation to postpartum thyroiditis. Autoimmunity 1990; 6(3):211-214 63. A K Rasmussen, L Kayser, K Bech, U Feldt-Rasmussen, H Perrild, K Bendtzen Differential effects of interleukin 1 alpha and 1 beta on cultured human and rat thyroid epithelial cells. Acta Endocrinol (Copenh) 1990; 122(4):520-526 64. N G Rasmussen, P J Hornnes, M Høier-Madsen, U Feldt-Rasmussen, L Hegedüs Thyroid size and function in healthy pregnant women with thyroid autoantibodies. Relation to development of postpartum thyroiditis. Acta Endocrinol (Copenh) 1990; 123(4):395-401 65. U Feldt-Rasmussen, M Høier-Madsen, J Date, M Blichert-Toft Evidence for acute release of thyroid peroxidase during subtotal thyroidectomy. Acta Endocrinol (Copenh) 1991; 124(6):661-665 66. J M Hansen, U Feldt-Rasmussen, C Kirkegaard, S Madsbad, O Elbrønd, O Greisen, H S Hansen, K Jørgensen, I Hessov, M Blichert-Toft Forslag om thyreoideakirurgiens strukturering og visitationsforhold i Danmark. Ugeskr Laeger 1991; 153(30):2136-2137 67. K Bech, J Hertel, N G Rasmussen, L Hegedüs, P J Hornnes, U Feldt-Rasmussen, M Høier-Madsen Effect of maternal thyroid autoantibodies and post-partum thyroiditis on the fetus and neonate. Acta Endocrinol (Copenh) 1991; 125(2):146-149

20 68. M Hørding, U F Feldt-Rasmussen Akut iridocyclitis med feber og leverpåvirkning ved kinidinbehandling. Ugeskr Laeger 1991; 153(34):2362-2363 69. L Hegedüs, J M Hansen, U Feldt-Rasmussen, B M Hansen, M Høier-Madsen Influence of thyroxine treatment on thyroid size and anti-thyroid peroxidase antibodies in Hashimoto's thyroiditis. Clin Endocrinol (Oxf) 1991; 35(3):235-238 70. L Kayser, H Perrild, U Feldt-Rasmussen, L Hegedüs, L Skovsted, J E Hansen The thyroid function and size in healthy man during 3 weeks treatment with beta-adrenoceptor-antagonists. Hormone and Metabolic Research 1991; 23(1):35-37 71. U Feldt-Rasmussen, M Høier-Madsen, K Bech, M Blichert-Toft, H Bliddal, J Date, B Danneskiold-Samsøe, L Hegedüs, E Hippe, P J Hornnes Anti-thyroid peroxidase antibodies in thyroid disorders and non-thyroid autoimmune diseases. Autoimmunity 1991; 9(3):245-254 72. U Feldt-Rasmussen, L Sestoft, H Berg Thyroid function tests in patients with acquired immune deficiency syndrome and healthy HIV1-positive out-patients. Eur J Clin Invest 1991; 21(1):59-63 73. A K Rasmussen, L Kayser, K Bech, U Feldt-Rasmussen, H Perrild, K Bendtzen Influence of interleukin 6 on the function of secondary cultures of human thyrocytes. Acta Endocrinol (Copenh) 1991; 124(5):577-582 74. A K Rasmussen, L Kayser, U Feldt-Rasmussen, K Bech, K Bendtzen, M Diamant, H Perrild Interleukin-6 is not a second mediator of interleukin-1 induced suppression of thyroid function in cultured human thyrocytes. Exp Clin Endocrinol 1991; 97(2-3):179-181 75. K Bech, M Høier-Madsen, U Feldt-Rasmussen, B M Jensen, L Mølsted-Pedersen, C Kühl Thyroid function and autoimmune manifestations in insulin-dependent diabetes mellitus during and after pregnancy. Acta Endocrinol (Copenh) 1991; 124(5):534-539 76. U Feldt-Rasmussen Postpartum thyroid dysfunction. Thyroid 1992; 2(1):83-84 77. U Feldt-Rasmussen, M Høier-Madsen, K Bech, M Blichert-Toft, J Date, L Hegedüs, P J Hornnes, H J Perrild, N G Rasmussen Måling af anti-thyreoidea-peroxidase-antistoffer som erstatning for mikrosomale og tyreoglobulinantistoffer. Ugeskr Laeger 1992; 154(22):1559-1563 78. M Ottesen, U Feldt-Rasmussen, J Andersen, E Hippe, A Schouboe Anaemia perniciosa. En undersøgelse af sygdommens debutformer, samt den diagnostiske betydning af påvist indre faktor antistof og parietalcelleantistof. Ugeskr Laeger 1992; 154(52):3758-3762 79. T Zimmermann-Belsing, A M Rønn, U Feldt-Rasmussen, J Kirkegaard Invasiv fibrøs thyreoiditis- -Riedel's struma. En gennemgang af litteraturen og diskussion af en sygehistorie. Ugeskr Laeger 1993; 155(15):1121-1125 80. *U Feldt-Rasmussen, H Schleusener, P Carayon Meta-analysis evaluation of the impact of thyrotropin receptor antibodies onlong term remission after medical therapy of Graves' disease. J Clin Endocrinol Metab 1994; 78(1):98-102* Impact factor 5.6 81. U Feldt-Rasmussen, L Hegedüs, M Ferrand, P Carayon Bispecific thyroglobulin and thyroperoxidase autoantibodies in patients withvarious thyroid and autoimmune diseases. J Clin Endocrinol Metab 1994; 79(5):1404-1409 82. A K Rasmussen, R Di Marco, M Diamant, U Feldt-Rasmussen, K Bendtzen Nitric oxide production is not involved in the effects of interleukin-1 beta on cAMP, thyroglobulin and interleukin-6 in TSH-stimulated human thyroid cells. Autoimmunity 1994; 19(4):239-245 83. T Zimmermann-Belsing, U Feldt-Rasmussen: Riedel's thyroiditis: an autoimmune or primary fibrotic disease? J Intern Med 1994; 235(3):271-274 84. A K Rasmussen, L Kayser, U Feldt-Rasmussen, K Bendtzen Influence of tumour necrosis factor- alpha, tumour necrosis factor-beta and interferon-gamma, separately and added together with interleukin-1 beta, on the function of cultured human thyroid cells. J Endocrinol 1994; 143(2):359- 365

21 85. H Perrild, A Grüters-Kieslich, U Feldt-Rasmussen, D Grant, E Martino, L Kayser, F Delange Diagnosis and treatment of thyrotoxicosis in childhood. A European questionnaire study. European Journal of Endocrinology 1994; 131(5):467-473 86. M Ottesen, U Feldt-Rasmussen, J Andersen, E Hippe, A Schouboe Thyroid function and autoimmunity in pernicious anemia before and during cyanocobalamin treatment. J Endocrinol Invest 1995; 18(2):91-97 87. H L Kristensen, U Feldt-Rasmussen, M Blichert-Toft Indikation for tyroxinbehandling efter operation for ikke endemisk atoksisk struma. Ugeskr Læger 1995; 157(17):2423-2426 88. B Schaadt, U Feldt-Rasmussen, B Rasmusson, H Tørring, B Foder, K Jørgensen, H S Hansen. Assessment of the influence of thyroglobulin (Tg) autoantibodies and other interfering factors on the use of serum Tg as tumor marker in differentiated thyroid carcinoma. Thyroid 1995; 5(3):165- 170 89. M Blichert-Toft, U Feldt-Rasmussen Thyreoideakirurgi-hvem skal operere? Ugeskr Læger 1995; 157(43):0-5969 90. *A K Rasmussen, L Kayser, H Perrild, M Brandt, K Bech, U Feldt-Rasmussen: Human thyroid epithelial cells cultured in monolayers. II. Influence of serum on thyroglobulin and cAMP production. Mol Cell Endocrinol 1996; 116(2):173-179 * Impact factor 3.69 91. T Zimmermann-Belsing, C L Mollerup, A Rabøl, B K Schaadt, L H Christensen, M Blichert-Toft, U Feldt-Rasmussen: Praeoperativ scintigrafisk lokalisation af hyperfungerende parathyreoideakirtler. Ugeskr Læger 1996; 158(13):1827-1831 92. A K Rasmussen, L Kayser, H Perrild, M Brandt, K Bech, U Feldt-Rasmussen: Human thyroid epithelial cells cultured in monolayers. I. Decreased thyroglobulin and cAMP response to TSH in 12-week-old secondary and tertiary cultures. Mol Cell Endocrinol 1996; 116(2):165-172 93. J Date, U Feldt-Rasmussen, M Blichert-Toft, L Hegedüs, H P Graversen Long-term observation of serum thyroglobulin after resection of nontoxic goiter and relation to ultrasonographically demonstrated relapse. World J Surg 1996; 20(3):351-6 94. U Feldt-Rasmussen, C Profilis, E Colinet, E Black, H Bornet, P Bourdoux, P Carayon, U B Ericsson, D A Koutras, L Lamas de Leon, P DeNayer, F Pacini, G Palumbo, A Santos, M Schlumberger, C Seidel, A J Van Herle, J J De Vijlder Human thyroglobulin reference material (CRM 457). 1st Part: Assessment of homogeneity, stability and immunoreactivity. Ann Biol Clin (Paris) 1996; 54(10-11):337-342 95. U Feldt-Rasmussen, C Profilis, E Colinet, E Black, H Bornet, P Bourdoux, P Carayon, U B Ericsson, D A Koutras, L Lamas de Leon, P DeNayer, F Pacini, G Palumbo, A Santos, M Schlumberger, C Seidel, A J Van Herle, J J DeVijlder Human thyroglobulin reference material (CRM 457). 2nd Part: Physicochemical characterization and certification. Ann Biol Clin (Paris) 1996; 54(10-11):343-348 96. N Vahl, S B Jensen, M H Rasmussen, S Susgaard, J O Jørgensen, J S Christiansen, U F Rasmussen, J Hilsted Bioavailability of recombinant human growth hormone in different concentrations and formulations. Pharmacol Toxicol 1996; 79(3):144-149 97. P K Nielsen, A K Rasmussen, U Feldt-Rasmussen, M Brandt, L Christensen, K Olgaard Ectopic production of intact parathyroid hormone by a squamous cell lung carcinomain vivo and in vitro. J Clin Endocrinol Metab 1996; 81(10):3793-3796 98. P K Nielsen, U Feldt-Rasmussen, K Olgaard A Direct effect in vitro of phosphate on PTH release from bovine parathyroid tissue slices but not from dispersed parathyroid cells. Nephrol Dial Transplant 1996; 11(9):1762-1768 99. J I Reimers, A K Rasmussen, A E Karlsen, U Bjerre, H Liang, O Morin, H U Andersen, T Mandrup-Poulsen, A G Burger, U Feldt-Rasmussen, J Nerup Interleukin-1 beta inhibits rat thyroid cell function in vivo and in vitro by an NO-independent mechanism and induces

22 hypothyroidism and accelerated thyroiditis in diabetes-prone BB rats. J Endocrinol 1996; 151(1):147-157. 100. P Clausen, B Feldt-Rasmussen, P Jacobsen, K Rossing, H H Parving, P K Nielsen, U Feldt- Rasmussen, K Olgaard Microalbuminuria as an early indicator of osteopenia in male insulin- dependent diabetic patients. Diab. Metab. 1997; 14(12):1038-1043 101. U Feldt-Rasmussen: Autoimmune thyreoideasygdomme ved graviditet og fødsel. Ugeskr Laeger 1997; 159(8):0-1063 102. P K Nielsen, A K Rasmussen, R Butters, U Feldt-Rasmussen, K Bendtzen, R Diaz, E M Brown, K Olgaard Inhibition of PTH secretion by interleukin-1 beta in bovine parathyroid glands in vitro is associated with an up-regulation of the calcium-sensing receptor mRNA. Biochem Biophys Res Commun 1997; 238(3):880-885 103. A K Rasmussen, M Diamant, M Blichert-Toft, K Bendtzen, U Feldt-Rasmussen: The effects of interleukin-1beta (IL-1beta) on human thyrocyte functions are counteracted by the IL-1 receptor antagonist. Endocrinology 1997; 138(5):2043-2048 104. K Bendtzen, U F Feldt-Rasmussen: Kemokiner og HIV-infektion. Ugeskr Laeger 1997; 159(13):1956-1957 105. A K Rasmussen, L Hilsted, H Perrild, E Christiansen, K Siersbaek-Nielsen, U Feldt-Rasmussen: Discrepancies between thyrotropin (TSH) measurement by four sensitive immunometric assays. Clinica Chimica Acta 1997; 259(1-2):117-128 106. A K Rasmussen, U Feldt-Rasmussen, N E Skakkebaek, J O Jørgensen, J S Christiansen, J Müller Autoimmune thyrotoxicosis developed during growth hormone (GH) treatment of an adult with childhood onset GH-deficiency. A causal relationship? Autoimmunity 1998; 27(1):57-61 107. T Zimmermann-Belsing, M Dreyer, J J Holst, U Feldt-Rasmussen: The relationship between the serum leptin concentrations of thyrotoxic patients during treatment and their total fat mass is different from that of normal subjects. Clin Endocrinol (Oxf) 1998; 49(5):589-595 108. T Zimmermann-Belsing, A K Rasmussen, U Feldt-Rasmussen: Lack of thyroglobulin synthesis as an indicator of early random dedifferentiation of the Fischer rat thyroid cell line FRTL-5. Scand J Clin Lab Invest 1998; 58(7):529-535 109. A Juul, N Vahl, J O Jørgensen, J S Christiansen, S B Sneppen, U Feldt-Rasmussen, N E Skakkebaek Consequences of stopping growth hormone (GH) therapy in young GH deficient patients with childhood onset disease. Growth Horm IGF Res 1998; 8 15-19 110. B A Bengtsson, H P Koppeschaar, R Abs, H Bennmarker, E Hernberg-Ståhl, B Westberg, P Wilton, J P Monson, U Feldt-Rasmussen, C Wüster Growth hormone replacement therapy is not associated with any increase in mortality. KIMS Study Group. J Clin Endocrinol Metab 1999; 84(11):4291- 4292 111. M L Hartoft-Nielsen, J Date, U Feldt-Rasmussen, M Blichert-Toft, L Hegedüs Serumtyreoglobulin sammenholdt med UL-påvist strumarecidiv. Ugeskr Laeger 1999; 161(16):2352-2357 112. A K Rasmussen, U Feldt-Rasmussen, M Brandt, M L Hartoft-Nielsen, P Carayon, K Buschard Thyrotropin stimulates specifically the expression of the autoantibody binding domains of the thyroperoxidase molecule. Autoimmunity 1999; 29(4):323-331 113. V Estienne, C Duthoit, V D Costanzo, P J Lejeune, M Rotondi, S Kornfeld, R Finke, J H Lazarus, U Feldt-Rasmussen, W G Franke, P Smyth, M D'Herbomez, B Conte-Devolx, L Persani, C Carella, J R Jourdain, M Izembart, M E Toubert, A Pinchera, A Weetman, R Sapin, P Carayon, J Ruf Multicenter study on TGPO autoantibody prevalence in various thyroid and non-thyroid diseases; relationships with thyroglobulin and thyroperoxidase autoantibody parameters. European Journal of Endocrinology 1999; 141(6):563-569

23 114. L Lavard, A Sehested, B Brock Jacobsen, J Muller, H Perrild, U Feldt-Rasmussen, J Parma, G Vassart Long-term follow-Up of an infant with thyrotoxicosis due to germline mutation of the TSH receptor gene (Met453Thr). Hormone Research 1999; 51(1):43-46 115. T Zimmermann-Belsing, A K Rasmussen, U Feldt-Rasmussen: Lack of thyroglobulin production supports the finding of the FRTL-5 cells with a nondiploid karyotype. Thyroid 1999; 9(5):519-520 116. B A Bengtsson, R Abs, H Bennmarker, J P Monson, U Feldt-Rasmussen, E Hernberg-Stahl, B Westberg, P Wilton, C Wüster The effects of treatment and the individual responsiveness to growth hormone(GH) replacement therapy in 665 GH-deficient adults. KIMS Study Group and the KIMS International Board. J Clin Endocrinol Metab 1999; 84(11):3929-3935 117. H Mersebach, A K Rasmussen, L Kirkegaard, U Feldt-Rasmussen: Intestinal adsorption of levothyroxine by antacids and laxatives: case stories and in vitro experiments. Pharmacol Toxicol 1999; 84(3):107-109 118. A K Rasmussen, U F Feldt-Rasmussen: Radioiodbehandling og thyreoidea-associeret oftalmopati ved Graves' sygdom. Ugeskr Laeger 1999; 161(43):5933-5934 119. K Howlett, H Galbo, J Lorentsen, R Bergeron, T Zimmerman-Belsing, J Bülow, U Feldt- Rasmussen, M Kjaer Effect of adrenaline on glucose kinetics during exercise in adrenalectomised humans. J Physiol 1999; 519 911-921 120. T Zimmermann-Belsing, A M Lund, L Christensen, U Feldt-Rasmussen: Co-existence of osteogenesis imperfecta and hyperparathyroidism. J Endocrinol Invest 1999; 22(7):547-550 121. M Schmiegelow, S Lassen, H S Poulsen, U Feldt-Rasmussen, K Schmiegelow, H Hertz, J Müller Cranial radiotherapy of childhood brain tumours: growth hormone deficiency and its relation to the biological effective dose of irradiation in a large population based study. Clin Endocrinol (Oxf) 2000; 53(2):191-197 122. A K Rasmussen, K Bendtzen, U Feldt-Rasmussen: Thyrocyte-interleukin-1 interactions. Exp Clin Endocrinol Diabetes 2000; 108(2):67-71 123. L Christensen, M Blichert-Toft, M Brandt, M Lange, S B Sneppen, J Ravnsbaek, C L Mollerup, L Strange, F Jensen, J Kirkegaard, H Sand Hansen, S S Sørensen, U Feldt-Rasmussen: Thy- roperoxidase (TPO) immunostaining of the solitary cold thyroid nodule. Clin Endocrinol (Oxf) 2000; 53(2):161-169 124. *G Brabant, R Horn, A von zur Mühlen, B Mayr, U Wurster, F Heidenreich, D Schnabel, A Grüters-Kieslich, T Zimmermann-Belsing, U Feldt-Rasmussen: Free and protein bound leptin are distinct and independently controlled factors in energy regulation. Diabetologia 2000; 43(4):438-442 * Impact factor 7.11 125. J P Monson, B A Bengtsson, R Abs, U Feldt-Rasmussen, C Wüster Can growth hormone therapy cause diabetes? KIMS Strategic Committee. The Lancet 2000; 355(9216):1728-1729 126. M Kjaer, K Howlett, J Langfort, T Zimmerman-Belsing, J Lorentsen, J Bulow, J Ihlemann, U Feldt-Rasmussen, H Galbo: Adrenaline and glycogenolysis in skeletal muscle during exercise: a study in adrenalectomised humans. J Physiol 2000; 528 371-378 127. T Zimmermann-Belsing, L Christensen, H S Hansen, J Kirkegaard, M Blichert-Toft, U Feldt- Rasmussen: A case of sarcoidosis and sarcoid granuloma, papillary carcinoma, and Graves' disease in the thyroid gland. Thyroid 2000; 10(3):275-278 128. P Ekbom, P Damm, K Nøgaard, P Clausen, U Feldt-Rasmussen, B Feldt-Rasmussen, L H Nielsen, L Mølsted-Pedersen, E R Mathiesen Urinary albumin excretion and 24-hour blood pressure as predictors of pre-eclampsia in Type I diabetes. Diabetologia 2000; 43(7):927-931 129. A K Rasmussen, B Nygaard, U Feldt-Rasmussen (131)I and thyroid-associated ophthalmopathy. European Journal of Endocrinology 2000; 143(2):155-160 130. M Lange, U Feldt-Rasmussen, L Christensen, M Blichert-Toft Thyroperoxidase immunostaining in evaluation of thyroid nodules. Clin Endocrinol (Oxf) 2000; 52(6):0-797

24 131. M Schmiegelow, S Lassen, H S Poulsen, U Feldt-Rasmussen, K Schmiegelow, H Hertz, J Müller Growth hormone response to a growth hormone-releasing hormone stimulation test in a population- based study following cranial irradiation of childhood brain tumors. Hormone Research 2000; 54(2):53-59 132. S B Sneppen, K M Main, A Juul, L M Pedersen, L O Kristensen, N E Skakkebaek, U Feldt- Rasmussen: Sweat secretion rates in growth hormone disorders. Clin Endocrinol (Oxf) 2000; 53(5):601-608 133. J P Monson, R Abs, B A Bengtsson, H Bennmarker, U Feldt-Rasmussen, E Hernberg-Stâhl, M Thorén, B Westberg, P Wilton, C Wüster Growth hormone deficiency and replacement in elderly hypopituitary adults. KIMS Study Group. Clin Endocrinol (Oxf) 2000; 53(3):281-289 134. A Lando, K Holm, K Nysom, Rasmussen AK, U Feldt-Rasmussen, J H Petersen, J Müller Thyroid function in survivors of childhood acute lymphoblastic leukaemia: the significance of prophylactic cranial irradiation. Clin Endocrinol (Oxf) 2001; 55(1):21-25 135. U Feldt-Rasmussen: Radiojodbehandling af metastaserende cancere? Ugeskr Laeger 2001; 163(24):0-3367 136. U Feldt-Rasmussen: Iodine and cancer. Thyroid 2001; 11(5):483-486 137. M Lange, M Blichert-Toft, L H Christensen, M Brandt, S B Sneppen, J Ravnsbaek, C L Mollerup, L Strange, F Jensen, J Kirkegaard, H S Hansen, S S Sørensen, U Feldt-Rasmussen: TPO- immunfarvning af den solitaere, kolde thyreoideaknude. Ugeskr Laeger 2001; 163(32):4198-4201 138. M L Hartoft-Nielsen, A K Rasmussen , A Kaas, T Bock, K Buschard, U Feldt-Rasmussen: Linomide does not prevent spontaneous autoimmune thyroiditis in NOD mice. Autoimmunity 2001; 33(2):79-84 139. A K Rasmussen, H Mersebach, L Hasholt, K M Rosenberg, S A Sørensen, U Feldt-Rasmussen Fabrys sygdom--specifik terapi nu mulig. Ugeskr Laeger 2001; 163(39): 5382 140. C Duthoit, V Estienne, A Giraud, J M Durand-Gorde, A K Rasmussen, U Feldt-Rasmussen, P Carayon, J Ruf Hydrogen peroxide-induced production of a 40 kDa immunoreactive thyroglobulin fragment in human thyroid cells: the onset of thyroid autoimmunity? Biochem J 2001; 360 557-562 141. C Wüster, R Abs, B A Bengtsson, H Bennmarker, U Feldt-Rasmussen, E Hernberg-Ståhl, J P Monson, B Westberg, P Wilton The influence of growth hormone deficiency, growth hormone replacement therapy, and other aspects of hypopituitarism on fracture rate and bone mineral density. . J Bone Miner Res 2001; 16(2):398-405 142. S B Sneppen, M Lange, L M Pedersen, L Ø Kristensen L, K M Main, A Juul, N E Skakkebaek, U Feldt-Rasmussen: Total and free insulin-like growth factor I, insulin-like growth factor binding protein 3 and acid-labile subunit reflect clinical activity in acromegaly. Growth Horm IGF Res 2001; 11(6):384-391 143. J Lindholm, S Juul, J O Jørgensen, J Astrup, P Bjerre, U Feldt-Rasmussen, C Hagen, J Jørgensen, M Kosteljanetz, L Kristensen, P Laurberg, K Schmidt, J Weeke Incidence and late prognosis of cushing's syndrome: a population-based study. J Clin Endocrinol Metab 2001; 86(1):117-123 144. M Lange, J Thulesen, U Feldt-Rasmussen, N E Skakkebaek, N Vahl, J O Jørgensen, J S Christiansen, S S Poulsen, S B Sneppen, A Juul Skin morphological changes in growth hormone deficiency and acromegaly. European Journal of Endocrinology 2001; 145(2):147-153 145. P Ekbom, P Damm, B Feldt-Rasmussen, U Feldt-Rasmussen, J Mølvig, E R Mathiesen Pregnancy outcome in type 1 diabetic women with microalbuminuria. Diabetes Care 2001; 24(10):1739-1744 146. T Zimmermann-Belsing, U Feldt-Rasmussen, J J Holst Bestemmelse af frit og bundet leptin i serum: betydning under thyreoideasygdom? Ugeskr Laeger 2001; 163(27):0-3808

25 147. M B Ranke, U Feldt-Rasmussen, P Bang, R C Baxter, C Camacho-Hübner, D R Clemmons, A Juul, H Orskov, C J Strasburger How should insulin-like growth factor I be measured? A consensus statement. Hormone Research 2001; 55 106-109 148. U Feldt-Rasmussen, A K Rasmussen, H Mersebach, K M Rosenberg, L Hasholt, S A Sorensen Fabry disease: a new challenge in endocrinology and metabolism? European Journal of Endocrinology 2002; 146(6):741-742 149. T Zimmermann-Belsing, B Nygaard, A K Rasmussen, U Feldt-Rasmussen: Use of the 2nd generation TRAK human assay did not improve prediction of relapse after antithyroid medical therapy of Graves' disease. European Journal of Endocrinology 2002; 146(2):173-177 150. R Abs, B A Bengtsson, A Luger, E Hernberg-Ståhl, B Westberg, J P Monson, P Wilton, U Feldt- Rasmussen: Healthcare consumption decreases in parallel with improvements in quality oflife during GH replacement in hypopituitary adults with GH deficiency. J Clin Endocrinol Metab 2002; 86(11):5277-5281 151. T Zimmermann-Belsing, U Feldt-Rasmussen G From, H Perrild, T C Bøg-Hansen Long-term pathologic changes of alpha1-acid glycoprotein (orosomucoid) glycoforms in autoimmune thyroid disease. Autoimmunity 2002; 35(7):441-447 152. T Zimmermann-Belsing, U Feldt-Rasmussen, H Fledelius Ultrasound measurement of the horizontal external eye muscles in patients with thyroid disease. Is orbital involvement associated with thyroid autoantibodies? European Journal of Ophthalmology 2002; 12(5):351-358 153. S B Sneppen, H Mersebach, H Ullum, U Feldt-Rasmussen: Immune function during GH treatment in GH-deficient adults: an 18-month randomized, placebo-controlled, double-blinded trial. Clin Endocrinol (Oxf) 2002; 57(6):787-792 154. U Feldt-Rasmussen, R Abs, B-A Bengtsson, H Bennmarker, M Bramnert, E Hernberg-Ståhl, J P Monson, B Westberg, P Wilton, C Wüster Growth hormone deficiency and replacement in hypopituitary patients previously treated for acromegaly or Cushing's disease. European Journal of Endocrinology 2002; 146(1):67-74 155. S B Sneppen, F Steensgaard-Hansen, U Feldt-Rasmussen: Cardiac effects of low-dose growth hormone replacement therapy in growth hormone-deficient adults. An 18-month randomised, placebo-controlled, double-blind study. Hormone Research 2002; 58(1):21-29 156. M Lange, O L Svendsen, N E Skakkebaek, J Müller, A Juul, M Schmiegelow, U Feldt- Rasmussen: An audit of the insulin-tolerance test in 255 patients with pituitary disease. European Journal of Endocrinology 2002; 147(1):41-47 157. H Mersebach, U Feldt-Rasmussen: Lokaliseret lipohypertrophia under behandling med vaeksthormon. Ugeskr Laeger 2002; 164(14):1930-1932 158. U Feldt-Rasmussen, K T Brixen Nye diagnostiske muligheder og ny organisering af behandlingstilbud ved multipel endokrin neoplasi. Ugeskr Laeger 2002; 164(7):0-881 159. S Bjerregård Sneppen, H C Hoeck, G Kollerup, O H Sørensen, P Laurberg, U Feldt-Rasmussen Bone mineral content and bone metabolism during physiological GH treatment in GH-deficient adults--an 18-month randomised, placebo-controlled, double blinded trial. European Journal of Endocrinology 2002; 146(2):187-195 160. T Zimmermann-Belsing, A K Rasmussen, U Feldt-Rasmussen, T C Bøg-Hansen The influence of alpha1-acid glycoprotein (orosomucoid) and its glycoforms on the function of human thyrocytes and CHO cells transfected with the human TSH receptor. Mol Cell Endocrinol 2002; 188(1-2):241- 251 161. P Vestergaard, J Lindholm, J O L Jørgensen, C Hagen, H C Hoeck, P Laurberg, L Rejnmark, K Brixen, L Ø Kristensen, U Feldt-Rasmussen, L Mosekilde Increased risk of osteoporotic fractures in patients with Cushing's syndrome. European Journal of Endocrinology 2002; 146(1):51-56

26 162. H Mersebach, O L Svendsen, J J Holst, A Astrup, U Feldt-Rasmussen: Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals. Clin Endocrinol (Oxf) 2003; 58(1):65-71 163. T Zimmermann-Belsing, G Brabant, J J Holst, U Feldt-Rasmussen: Circulating leptin and thyroid dysfunction. European Journal of Endocrinology 2003; 149(4):257-271 164. H C Fledelius, T Zimmermann-Belsing, U Feldt-Rasmussen: Ultrasonically measured horizontal eye muscle thickness in thyroid associated orbitopathy: cross-sectional and longitudinal aspects in a Danish series. Acta Ophthalmologica Scandinavica 2003; 81(2):143-150 165. *Z Baloch, P Carayon, B Conte-Devolx, L M Demers, U Feldt-Rasmussen J-F Henry, V A LiVosli, P Niccoli-Sire, R John, J Ruf, P P A Smyth, C A Spencer, J R Stockigt Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid disease. Thyroid 2003; 13(1):3-126* Impact factor 7.78 166. T V Elberling, E R Danielsen, A K Rasmussen, U Feldt-Rasmussen G Waldemar, C Thomsen Reduced myo-inositol and total choline measured with cerebral MRS in acute thyrotoxic Graves' disease. Neurology 2003; 60(1):142-145 167. M Schmiegelow, U Feldt-Rasmussen A K Rasmussen, H S Poulsen, J Müller A population-based study of thyroid function after radiotherapy and chemotherapyfor a childhood brain tumor. J Clin Endocrinol Metab 2003; 88(1):136-140 168. M Schmiegelow, U Feldt-Rasmussen A K Rasmussen, M Lange, H S Poulsen, J Müller Assessment of the hypothalamo-pituitary-adrenal axis in patients treated with radiotherapy and chemotherapy for childhood brain tumor. J Clin Endocrinol Metab 2003; 88(7):3149-3154 169. Ph Caron, M Bex, D R Cullen, U Feldt-Rasmussen A M Pico Alfonso, S Pynka, K Racz, J Schopohl, A Tabarin, M J Valimaki One-year follow-up of patients with acromegaly treated with fixed or titrated doses of lanreotide Autogel. Clin Endocrinol (Oxf) 2004; 60(6):734-740 170. T Zimmermann-Belsing, A Juul, J J Holst, U Feldt-Rasmussen: The insulin-like growth axis in patients with autoimmune thyrotoxicosis: effect of antithyroid drug treatment. Growth Horm IGF Res 2004; 14(3):235-244 171. B S Rasmussen, A K Rasmussen, U Feldt-Rasmussen: Thyroideahormonresistens. Ugeskr Laeger 2004; 166(3):166-167 172. A Lando, K Holm, K Nysom, A K Rasmussen, M H Madsen, U Feldt-Rasmussen, J Müller Serum thyroglobulin as a marker of thyroid neoplasms after childhood cancer. Acta Paediatr 2004; 92(11):1284-1290 173. E Hubina, H Mersebach, A K Rasmussen, A Juul, S B Sneppen, M I Góth, U Feldt-Rasmussen: Effect of growth hormone replacement therapy on pituitary hormone secretion and hormone replacement therapies in GHD adults. Hormone Research 2004; 61(5):211-217 174. M-L Hartoft-Nielsen, M Lange, A K Rasmussen, S Scherer, T Zimmermann-Belsing, U Feldt- Rasmussen: Thyrotropin-releasing hormone stimulation test in patients with pituitary pathology. Hormone Research 2004; 61(2):53-57 175. H Mersebach, M Klose, O L Svendsen, A Astrup, U Feldt-Rasmussen: Combined dietary and pharmacological weight management in obese hypopituitary patients. Obes Res 2004; 12(11):1835- 1843 176. M-L Hartoft-Nielsen, A K Rasmussen, E Friis, M Blichert-Toft, T Buhl, B Hesse, U Feldt- Rasmussen: Unsuccessful radioiodine treatment of a non-toxic goiter: a case report. Basic Clin Pharmacol Toxicol 2004; 95(2):72-75 177. M-L Hartoft-Nielsen, A K Rasmussen, A Kaas, U Feldt-Rasmussen, K Buschard Neonatal stimulation of the thyroid gland with iodine or suppression during adolescence with triiodothyronine changes the prevalence of autoimmune thyroiditis in BB rats. European Journal of Endocrinology 2004; 151(3):375-382

27 178. D Hesse, M-L C Hartoft-Nielsen, O Snorgaard, H J Perrild, A K Rasmussen, U Feldt-Rasmussen: Effekt af opløselige kostfibre på den glykaemiske regulering og lipidstatus ved type 2-diabetes. Ugeskr Laeger 2004; 166(20):1899-1902 179. U Feldt-Rasmussen, P Wilton, P Jonsson Aspects of growth hormone deficiency and replacement in elderly hypopituitary adults. Growth Horm IGF Res 2004; 14 S51-58 180. T Zimmermann-Belsing, U Feldt-Rasmussen: Obesity: the new worldwide epidemic threat to general health and our complete lack of effective treatment. Endocrinology 2004; 145(4):1501-1502 181. T V Elberling, A K Rasmussen, U Feldt-Rasmussen, M Hørding, H Perrild, G Waldemar Impaired health-related quality of life in Graves' disease. A prospective study. European Journal of Endocrinology 2004; 151(5):549-555 182. H Mersebach, O L Svendsen, A Astrup, U Feldt-Rasmussen: Abnormal sympathoadrenal activity, but normal energy expenditure in hypopituitarism. J Clin Endocrinol Metab 2004; 88(12):5689- 5695 183. *M Lange, K Qvortrup, O L Svendsen, A Flyvbjerg, J Nowak, M M Petersen, K Ølgaard, U Feldt- Rasmussen: Abnormal bone collagen morphology and decreased bone strength in growth hormone-deficient rats. BONE 2004; 35(1):178-185* Impact factor 4.36 184. M Lange, U Feldt-Rasmussen O L Svendsen, K W Kastrup, A Juul, J Müller High risk of adrenal insufficiency in adults previously treated for idiopathic childhood onset growth hormone deficiency. J Clin Endocrinol Metab 2004; 88(12):5784-5789 185. H Mersebach, U Feldt-Rasmussen: Growth hormone and body composition. Front Horm Res 2005; 33 185-195 186. J J Christiansen, S Fisker, C H Gravholt, P Bennett, B Svenstrup, M Andersen, U Feldt- Rasmussen, J S Christiansen, J O L Jørgensen Discontinuation of estrogen replacement therapy in GH-treated hypopituitary women alters androgen status and IGF-I. European Journal of Endocrinology 2005; 152(5):719-726 187. J O L Jørgensen, U Feldt-Rasmussen, J Frystyk, J-W Chen, L Ø Kristensen, C Hagen, H Ørskov Cotreatment of Acromegaly with a Somatostatin Analogue and a Growth HormoneReceptor Antagonist. J Clin Endocrinol Metab 2005; 90(10):5627-5631. 188. P M Mah, J Webster, P Jönsson, U Feldt-Rasmussen, M Koltowska-Häggström, R J M Ross Oestrogen replacement in hypopituitary women of fertile years. J Clin Endocrinol Metab 2005; 90(11):5964-5969. 189. M Klose, M Lange, M Kosteljanetz, L Poulsgaard, U Feldt-Rasmussen: Adrenocortical insufficiency after pituitary surgery: an audit of the reliability of the conventional short synacthen test. Clin Endocrinol (Oxf) 2005; 63(5):499-505 190. M L Hartoft-Nielsen, A K Rasmussen, U Feldt-Rasmussen, K Buschard, T Bock Estimation of number of follicles, volume of colloid and inner follicular surface area in the thyroid gland of rats. J Anat 2005; 207(2):117-124 191. M Lange, J Müller, O L Svendsen, K W Kastrup, A Juul, U Feldt-Rasmussen: The impact of idiopathic childhood-onset growth hormone deficiency (GHD) on bone mass in subjects without adult GHD. Clin Endocrinol (Oxf) 2005; 62(1):18-23 192. R Abs, A F Mattsson, B-A Bengtsson, U Feldt-Rasmussen, M I Góth, M Koltowska-Häggström, J P Monson, J Verhelst, P Wilton Isolated growth hormone (GH) deficiency in adult patients: baseline clinical characteristics and responses to GH replacement in comparison with hypopituitary patients. A sub-analysis of the KIMS database. Growth Horm IGF Res 2005; 15(5):349-359 193. R Abs, U Feldt-Rasmussen, A F Mattsson, J P Monson, B-A Bengtsson, M I Góth, P Wilton, M Koltowska-Häggström Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults - a KIMS database analysis. European Journal of Endocrinology 2006; 155(1):79-90

28 194. K Stochholm, C H Gravholt, T Laursen, J O Jørgensen, P Laurberg, M Andersen, Lars Ø Kristensen, U Feldt-Rasmussen, J S Christiansen, M Frydenberg, A Green Incidence of GH deficiency - a nationwide study. European Journal of Endocrinology 2006; 155(1):61-71 195. A T Moller, U Feldt-Rasmussen, A K Rasmussen, C Sommer, L Hasholt, F W Bach, S Kølvraa, T S Jensen Small-fibre neuropathy in female Fabry patients: reduced allodynia and skin blood flow after topical capsaicin. J Peripher Nerv Syst 2006; 11(2):119-125 196. A C Jäger, L Friis-Hansen, T V O Hansen, P C Eskildsen, K Sølling, U Knigge, C P Hansen, P H Andersen, K Brixen, U Feldt-Rasmussen, J P Kroustrup, C L Mollerup, J F Rehfeld, M Blichert- Toft, F C Nielsen Characteristics of the Danish families with multiple endocrine neoplasia type 1. Mol Cell Endocrinol 2006; 249(1-2):123-132 197. P Ekbom, P Damm, A-M Andersson, N E Skakkebaek, U Feldt-Rasmussen, E R Mathiesen Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnancies. Acta Obstet Gynecol Scand 2006; 85(2):143-147 198. F Pacini, M Schlumberger, H Dralle, R Elisei, J W A Smit, W Wiersinga, U Feldt-Rasmussen European consensus for the management of patients with differentiated thyroid carcinoma of the follicular epithelium. European Journal of Endocrinology 2006; 154(6):787-803 199. K M Main, A Sehested, U Feldt-Rasmussen: Pegvisomant treatment in a 4-year-old girl with neurofibromatosis type 1. Hormone Research 2006; 65(1):1-5 200. A Vogel, T V Elberling, M Hørding, J Dock, A K Rasmussen, U Feldt-Rasmussen, H Perrild, G Waldemar Affective symptoms and cognitive functions in the acute phase of Graves' thyrotoxicosis. Psychoneuroendocrinology 2007; 32(1):36-43 201. T Watt, L Hegedüs, A K Rasmussen, M Groenvold, S J Bonnema, J B Bjorner, U Feldt- Rasmussen: Which domains of thyroid-related quality of life are most relevant? Patients and clinicians provide complementary perspectives. Thyroid 2007; 17(7):647-654* Impact factor 7.78 202. H Mersebach, J-O Johansson, A K Rasmussen, B-A Bengtsson, K Rosenberg, L Hasholt, S A Sørensen, S S Sørensen, U Feldt-Rasmussen: Osteopenia: a common aspect of Fabry disease. Predictors of bone mineral density. Genet Med 2007; 9(12):812-818 203. M Klose, T Watt, J Brennum, U Feldt-Rasmussen: Posttraumatic hypopituitarism is associated with an unfavorable body composition and lipid profile, and decreased quality of life 12 months after injury. J Clin Endocrinol Metab 2007; 92(10):3861-3868 204. K Stochholm, C Højbjerg Gravholt, T Laursen, P Laurberg, M Andersen, L Ø Kristensen, U Feldt- Rasmussen, J Sandahl Christiansen, M Frydenberg, A Green Mortality and GH deficiency: a nationwide study. European Journal of Endocrinology 2007; 157(1):9-18 205. M Klose, A Juul, J Struck, N G Morgenthaler, M Kosteljanetz, U Feldt-Rasmussen: Acute and long-term pituitary insufficiency in traumatic brain injury: a prospective single-centre study. Clin Endocrinol (Oxf) 2007; 67(4):598-606 206. P Clausen, P Ekbom, P Damm, U Feldt-Rasmussen, B Nielsen, E R Mathiesen, B Feldt- Rasmussen Signs of maternal vascular dysfunction precede preeclampsia in women with type 1 diabetes. J Diabetes Complications 2007; 21(5):288-293 207. M Klose, A Juul, L Poulsgaard, M Kosteljanetz, J Brennum, U Feldt-Rasmussen: Prevalence and predictive factors of post-traumatic hypopituitarism. Clin Endocrinol (Oxf) 2007; 67(2):193-201 208. E I Christensen, Q Zhou, S S Sørensen, A K Rasmussen, C Jacobsen, U Feldt-Rasmussen, R Nielsen Distribution of alpha-galactosidase A in normal human kidney and renal accumulation and distribution of recombinant alpha-galactosidase A in Fabry mice. J Am Soc Nephrol 2007; 18(3):698-706 209. G Brabant, A K Rasmussen, B M K Biller, M Buchfelder, U Feldt-Rasmussen, K Forssmann, B Jonsson, M Koltowska-Haggstrom, D Maiter, B Saller, A Toogood. Clinical implications of

29 residual growth hormone (GH) response to provocative testing in adults with severe GH deficiency. J Clin Endocrinol Metab 2007; 92(7):2604-2609 210. U Yousaf, Lh Christensen, Ak Rasmussen, F Jensen, Emh Kruuse, Cl Mollerup, J Kirkegaard, I Lausen, F Rank, U Feldt-Rasmussen: Immunohistochemical staining for thyroid peroxidase (TPO) of needle core biopsies in the diagnosis of scintigraphically cold thyroid nodules. Clin Endocrinol (Oxf) 2008;68(6):996-1001. 211. M Klose, M Lange, A K Rasmussen, N E Skakkebaek, L Hilsted, E Haug, M Andersen, U Feldt- Rasmussen: Factors influencing the adrenocorticotropin test: role of contemporary cortisol assays, body composition, and oral contraceptive agents. J Clin Endocrinol Metab 2007; 92(4):1326-1333 212. L Agate, S Mariotti, R Elisei, P Mossa, F Pacini, E Molinaro, L Grasso, L Masserini, T Mokhort, T Vorontsova, A Arynchyn, M D Tronko, A Tsyb, U Feldt-Rasmussen, A Juul, A Pinchera Thyroid autoantibodies (ATA) and thyroid function in subjects exposed to Chernobyl fallout during childhood: evidence for a transient radiation-induced elevation of serum thyroid antibodies without an increase in thyroid autoimmune disease. J Clin Endocrinol Metab 2008; 93:2729-36 213. K Stochholm, T Laursen, A Green, P Laurberg, M Andersen, L Ø Kristensen, U Feldt-Rasmussen, J Sandahl Christiansen, M Frydenberg, C Højbjerg Gravholt Morbidity and GH deficiency: a nationwide study. European Journal of Endocrinology 2008; 158(4):447-457 214. P Ekbom, P Damm, B Feldt-Rasmussen, U Feldt-Rasmussen, D M Jensen, E R Mathiesen Elevated third-trimester haemoglobin A(1c) predicts preterm delivery in type 1 diabetes. J Diabetes Complications 2008; 22:297-302 215. M-L Hartoft-Nielsen, A K Rasmussen, T Bock, U Feldt-Rasmussen, A Kaas, K Buschard Iodine and tri-iodo-thyronine reduce the incidence of type 1 diabetes mellitus in the autoimmune prone BB rats. Autoimmunity 2008; 42:131-8. 216. W R Wilcox, J P Oliveira, R J Hopkin, A Ortiz, M Banikazemi, U Feldt-Rasmussen, K Sims, S Waldek, G M Pastores, P Lee, C M Eng, L Marodi, K E Stanford, F Breunig, C Wanner, D G Warnock, R M Lemay, D P Germain Females with Fabry disease frequently have major organ involvement: Lessons from the Fabry Registry. Mol Genet Metab 2008; 93(2):112-128 217. P Clausen, H Mersebach, B Nielsen, B Feldt-Rasmussen, U Feldt-Rasmussen: Hypothyroidism is associated with signs of endothelial dysfunction despite one year replacement therapy with levothyroxine. Clin Endocrinol (Oxf) 2009; 70:932-7 218. P Abrams, H Boquete, H Fideleff, U Feldt-Rasmussen, P Wilton, R Abs, M Koltowska- Haggstrom, P Jonsson Growth hormone replacement in hypopituitarism improves lipid profile and quality of life independently of changes in obesity variables. European Journal of Endocrinology 2008;159:825-32 219. T Watt, A Rasmussen, M Groenvold, J Bjorner, S Watt, S Bonnema, L Hegedüs U Feldt- Rasmussen: Improving a newly developed patient-reported outcome for thyroid patients, using cognitive interviewing. Qual Life Res 2008;17:1009-17 220. E R Danielsen, T V Elberling, A K Rasmussen, J Dock, M Hørding, H Perrild, G Waldemar, U Feldt-Rasmussen, C Thomsen Reduced parieto-occipital white matter glutamine measured by proton magnetic resonance spectroscopy in treated Graves' disease patients. J Clin Endocrinol Metab 2008; 93:3192-8. 221. Torquil Watt, Jakob Bue Bjorner, Mogens Groenvold, Aase Krogh Rasmussen, Steen Joop Bonnema, Laszlo Hegedüs, U Feldt-Rasmussen: Establishing construct validity for the thyroid- specific patient reported outcome measure (ThyPRO): an initial examination. Qual Life Res 2009; 18:483-496 222. Boas M, Hegedüs L, U Feldt-Rasmussen, Skakkebaek NE, Hilsted L, Main KM. Association of thyroid gland volume, serum insulin-like growth factor-I, and anthropometric variables in euthyroid prepubertal children. J Clin Endocrinol Metab. 2009; 94:4031-4035.

30 223. Touraine P, D'Souza GA, Kourides I, Abs R, Barclay P, Xie R, Pico A, Torres-Vela E, Ekman B; U Feldt-Rasmussen:GH Lipoatrophy Study Group. Lipoatrophy in GH deficient patients treated with a long-acting pegylated GH. Eur J Endocrinol. 2009; 161:533-540. 224. Torvin Møller A, Winther Bach F, U Feldt-Rasmussen, Rasmussen A, Hasholt L, Lan H, Sommer C, Kølvraa S, Ballegaard M, Staehelin Jensen T. Functional and structural nerve fiber findings in heterozygote patients with Fabry disease. Pain. 2009; 145:237-245. 225. Knorr U, Vinberg M, Klose M, U Feldt-Rasmussen, Hilsted L, Gade A, Haastrup E, Paulson O, Wetterslev J, Gluud C, Gether U, Kessing L.Rationale and design of the participant, investigator, observer, and data-analyst-blinded randomized AGENDA trial on associations between gene- polymorphisms, endophenotypes for depression and antidepressive intervention: the effect of escitalopram versus placebo on the combined dexamethasone-corticotrophine releasing hormone test and other potential endophenotypes in healthy first-degree relatives of persons with depression. Trials. 2009; 10:66. 226. Klose M, Jonsson B, Abs R, Popovic V, Koltowska-Häggström M, Saller B, U Feldt-Rasmussen, Kourides I. From isolated GH deficiency to multiple pituitary hormone deficiency: an evolving continuum - a KIMS analysis. Eur J Endocrinol. 2009; 161 Suppl 1:S75-83. 227. Boas M, Forman J, Juul A, U Feldt-Rasmussen, Skakkebaek N, Hilsted L, Chellakooty M, Larsen T, Larsen J, Petersen J, Main K. Narrow intra-individual variation of maternal thyroid function in pregnancy based on a longitudinal study of 132 women. Eur J Endocrinol. 2009; 161:903-910. 228. Watt T, Hegedus L, Groenvold M, Bjorner J, Rasmussen A, Bonnema S, U Feldt-Rasmussen: Validity and reliability of the novel thyroid-specific quality of life questionnaire, ThyPRO. Eur J Endocrinol. 2010. 162;161-167. 229. Lendorf ME, Rasmussen AK, Fledelius HC, U Feldt-Rasmussen: Cardiovascular and Cerebrovascular Events in Temporal Relationship to Intravenous Glucocorticoid Pulse Therapy in Patients with Severe Endocrine Ophthalmopathy. Thyroid. 2009; 19:1431-1432. 230. Roug S, Rasmussen AK, Juhler M, Kosteljanetz M, Poulsgaard L, Heebøll H, Roed H, U Feldt- Rasmussen: Fractionated stereotactic radiotherapy in patients with acromegaly: an interim single- centre audit. Eur J Endocrinol. 2010; 162:685-694. 231. Klose M, Brennum J, Poulsgaard L, Kosteljanetz M, Wagner A, U Feldt-Rasmussen: Hypopituitarism is uncommon after aneurysmal subarachnoid haemorrhage. Clin Endocrinol (Oxf). 2010; 73:95-101. 232. Höybye C, Ragnarsson O, Jönsson PJ, Koltowska-Häggström M, Trainer P, U Feldt-Rasmussen, Biller BM. Clinical features of GH deficiency and effects of 3 years of GH replacement in adults with controlled Cushing's disease. Eur J Endocrinol. 2010; 162(4):677-684. 233. Møller AT, Bach FW, U Feldt-Rasmussen, Rasmussen AK, Hasholt L, Sommer C, Kølvraa S, Jensen TS. Autonomic skin responses in females with Fabry disease. J Peripher Nerv Syst. 2009; 14(3):159-164. 234. Havndrup O, Christiansen M, Stoevring B, Jensen M, Hoffman-Bang J, Andersen PS, Hasholt L, Nørremølle A, U Feldt-Rasmussen, Køber L, Bundgaard H. Fabry disease mimicking hypertrophic cardiomyopathy: genetic screening needed for establishing the diagnosis in women. Eur J Heart Fail. 2010; 12:535-540. 235. Bliddal S, Sundberg K, Rasmussen Å.K., Brocks V & U Feldt-Rasmussen:. F. Intrauterine Diagnosis and Management of Fetal Goiter: A Case Report. Journal of Clinical Ultrasound. 2010; 38:503-505. 236. Belsing T. Z, Tofteng C. L., Langdahl, B. L, Charles, P. & U Feldt-Rasmussen: Can bone loss be reversed by antithyroid drug therapy in premenopausal women with Graves’ disease? Nutrition & Metabolism. 2010; 7;72.

31 237. Watt, T, Hegedüs L, Groenvold M, Bjorner J. B, Rasmussen Å. K, Bonnema S J & U Feldt- Rasmussen: Validity and reliability of the novel thyroid-specific quality of life questionnaire, ThyPRO. European Journal of Endocrinology. 2010; 162:161-167. 238. Boas M, Frederiksen H, U Feldt-Rasmussen, Skakkebæk N. E, Hegedüs L, Hilsted L. M, Juul A. & Main K. M. Environmental Health Perspectives. 2010; 118:1458-1464. 239. Watt T, Burlina A. P, Cazzorla C, Schönfeld D, Banikazemi M, Hopkin R. J, Martins A. M, Sims K, Beitner-Johnson D, O'Brien F. & U Feldt-Rasmussen: Agalsidase beta treatment is associated with improved quality of life in patients with Fabry disease: findings from the Fabry Registry. Journal of Endodontics. 2010; 12:703-712. 240. Haak C.S, Jensen P.N, Pedersen A.T, Clausen H.V, U Feldt-Rasmussen, Rasmussen Å. K, Main K. & Haedersdal M. Hair removal in hirsute women with normal testosterone levels: a randomized controlled trial of long-pulsed diode laser vs. intense pulsed light. British Journal of Dermatology. 2010; 163:1007-1013. 241. Doessing S, Holm L, Heinemeier K.M, U Feldt-Rasmussen, Schjerling P, Qvortrup K, Larsen J. O, Nielsen R. H, Flyvbjerg A. & Kjaer M. GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients. European Journal of Endocrinology. 2010; 163:853-862. 242. U Feldt-Rasmussen, Dobrovolny R, Nazarenko I, Ballegaard M, Hasholt L. F, Rasmussen A. K, Christensen E. I, Sorensen S. S, Wibrand F & Desnick R. Diagnostic dilemma: a young woman with Fabry disease symptoms, no family history, and a “sequencing cryptic” a-galactosidase a large deletion. Molecular Genetics and Metabolism. 2011; 104:314-318. 243. Knorr U, Vinberg M., Hansen A, Klose M, U Feldt-Rasmussen, Hilsted L, Hasselstrøm J. B, Gether U, Winkel P, Gluud C, Wetterslev J. & Kessing L. V. P L o S One. 2011; 6:e21224 244. Nielsen E.H, U Feldt-Rasmussen, Poulsgaard L, Kristensen L. O, Astrup J, Jørgensen J. O, Bjerre P. B, Andersen M, Andersen C, Jørgensen J, Lindholm J. & Laurberg P. Incidence of craniopharyngioma in Denmark (n=189) and estimated world incidence of craniopharyngioma in children and adults. Journal of Neuro-Oncology. 2011; 104:755-763. 245. Vindeløv S. D, Hartoft-Nielsen M-L, Rasmussen Å. K, Bendtzen K, Kosteljanetz M, Andersson A- M. & U Feldt-Rasmussen: Interleukin-8 production from human somatotroph adenoma cells is stimulated by interleukin-1β and inhibited by growth hormone releasing hormone and somatostatin. Growth Hormone & IGF Research. 2011; 21:134-139. 246. Prabakaran T, Nielsen R, Larsen J. V, Sørensen S. S, U Feldt-Rasmussen, Saleem M. A, Petersen C. M, Verroust P. J. & Christensen E. I. Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease. PLoS One. 2011; 6:e25065. 247. Bliddal S, Rasmussen Å K, Sundberg K, Brocks V, Skovbo P. & U Feldt-Rasmussen. Graves’ disease in two pregnancies complicated by fetal goitrous hypothyroidism: successful in utero treatment with levothyroxine. Thyroid. 2011; 21:75-81. 248. Søndergaard E, Klose M, Hansen M, Hansen B S, Andersen M, U Feldt-Rasmussen, Laursen T, Rasmussen M H & Christiansen J S. Pegylated Long-Acting Human Growth Hormone Possesses a Promising Once-Weekly Treatment Profile, and Miltiple Dosing Is Well Tolerated in Adult Patients with Growth Hormone Deficiency. The Journal of clinical endocrinology and metabolism. 2011; 96:681-688. 249. Wilcox W R, Linthorst G E, Germain D P, U Feldt-Rasmussen, Waldek S, Richards S M, Beitner- Johnson D, Cizmarik M, Cole J A, Kingma W & Warnock D G. Anti-α-galactosidase A antibody response to agalsidase beta treatment: data from the Fabry Registry. Molecular Genetics and Metabolism. 2012; 105:443-449. 250. Ragnarsson O, Höybye C, Jönsson P J, U Feldt-Rasmussen, Johannsson G, Biller B M K & Koltowska-Häggström M. Comorbidity and cardiovascular risk factors in adult GH deficiency

32 following treatment for Cushing’s disease or non-functioning pituitary adenomas during childhood. European Journal of Endocrinology. 2012; 166:593-600. 251. Marcocci C, Watt T, Altea M A, Rasmussen Å K, U Feldt-Rasmussen, Orgiazzi J, Bartalena L. & European Group of Graves' Orbitopathy. Fatal and non-fatal adverse events of glucocorticoid therapy for Graves’ orbitopathy: a questionnaire survey among members of the European Thyroid Association. European Journal of Endocrinology. 2012; 166:247-253. 252. Watt T, Bjørner J, Grønvold M, Bonnema S J, Rasmussen Å K & U Feldt-Rasmussen: Is Thyroid Autoimmunity per se a Determinant of Quality of Life in Patients with Autoimmune Hypothyroidism. European Thyroid Journal. 2012; 1:186-192. 253. Prabakaran T, Nielsen R S, Satchell S C, Mathieson P W, U Feldt-Rasmussen, Sørensen S S & Christensen E. Mannose 6-phosphate receptor and sortilin mediated andocytosis of α-galactosidase A in kidney endothelial cells. PLoS One. 2012; 7:e39975. 254. Gaillard R C, Mattsson A F, Akerblad A-C, Bengtsson B-Å, Cara J, U Feldt-Rasmussen, Koltowska-Häggström M, Monson J P, Saller B, Wilton P & Abs R. Overall and cause-specific mortality in GH-deficient adults on GH replacement. European Journal of Endocrinology. 2012; 166:1069-1077. 255. Klose M, Rasmussen Å K & U Feldt-Rasmussen: Quality of Life in Adult Hypopituitary Treated for Growth Hormone Deficiency. The Open Endocrinology Journal. 2012; 6:91-102 256. Linthorst G E, Burlina A P, Cecchi F, Cox T M, Fletcher J M, U Feldt-Rasmussen, Giugliani R, Hollak C E M, Houge G, Hughes D, Kantola I, Lachmann R, Lopez M, Ortiz A, Parini R, Rivera A, Rolfs A, Ramaswami U, Svarstad E, Tondel C, Tylki-Szymanska A, Vujkovac B, Waldek S, West M, Weidemann F & Mehta A. Recommendations on reintroduction of agalsidase Beta for pationts with fabry disease in Europe, following a period of shortage. JIMD reports. 2012; 8:51-56. 257. Toogood A, Brabant G, Maiter D, Jonsson B, U Feldt-Rasmussen, Koltowska-Haggstrom M, Rasmussen Å K, Buchfelder M, Saller B & Biller B M K. Similar clinical features among pationts with severe adult growth hormone deficiency diagnosed with insulin tolerance test or arginine or glucagon stimulation tests. Endocrine Practice. 2012: 18:325-334. 258. Filipsson Nyström H, U Feldt-Rasmussen, Kourides I, Popovic V, Koltowska-Häggström M, Jonsson B & Johannsson G. The metabolic consequences of thyrozine replacement in adult hypopituitary patients. Pituitary. 2012; 15: 495-504. 259. Blomberg M, U Feldt-Rasmussen, Andersen K K & Kjaer S K. Thyroid cancer in Denmark 143- 2008, before and after iodine supplementation. International Journal of Cancer. 2012; 131:2360- 2366. 260. Colao A, Petersenn S, Newell-Price J, Findling J W, Gu F, Maldonado M, Schoenherr U, Mills D, Salgado L R, Biller B M K, Pasireotide B2305 Study Group(U Feldt-Rasmussen). A 12-month phase 3 study of pasireotide in Cushing’s disease. New England Journal of Medicine. 2012; 366:914-924. 261. Nielsen E H, Jørgensen J O, Bjerre P B, Andersen M, Andersen C, U Feldt-Rasmussen, Poulsgaard L, Kristensen L O, Astrup J, Jørgensen J & Laurberg P M. Acute presentation of craniopharyngioma in children and adults in a Danish national cohort. Pituitary. 2013; 16: 528-535 262. Borgwardt L G, U Feldt-Rasmussen, Rasmussen A K, Ballegaard M & Lund A M. Fabry disease in children: agalsidase-beta enzyme replacement therapy. Clinical Genetics. 2013; 83:432-438. 263. Watt T, Cramon P, Bjorner J B, Bonnema S J, U Feldt-Rasmussen, Gluud C, Gram J, Hansen J L, Hegedüs L, Knudsen N, Bach-Mortensen P, Nolsöe R, Nygaard B, Pociot F, Skoog M, Winkel P & Rasmussen A K. Selenium supplementation for patients with Graves’ hyperthyroidism (the GRASS trial): study protocol for a randomized controlled trial. Trials. 2013; 14:119.

33 264. U Feldt-Rasmussen & Soderstrom F. Results and summary of voting among the audience during presentation and discussion of Medullary Thyroid Carcinoma clinical guidelines prepared by American Thyroid Association. Thyroid Research. 2013; 6:S1-S12. 265. U Feldt-Rasmussen, Brabant G, Maiter D, Jonsson B, Toogood A, Koltowska-Haggstrom M, Rasmussen Å K, Buchfelder M, Saller B & Biller B M K. Response to GH treatment in adult GH deficiency is predicted by gender, age and IGF1 SDS but not by stimulated GH-peak. European Journal of Endocrinology. 2013; 168:733-743. 266. Klose M, Marina D, Hartoft-Nielsen M-L, Klefter O, Gavan V, Hilsted L, Rasmussen Å K & U Feldt-Rasmussen. Central hypothyroidism and its replacement have a significant influence on cardiovascular risk factors in adult hypopituitary patients. Journal of Clinical Endocrinology and Metabolism. 2013; 98:3802-3810. 267. Ercolano M A, Drnovsek M L, Croome M C, Moos M, Fuentes A M, Viale F, U Feldt-Rasmussen & Gauna A T. Negative correlation between bone mineral density and TSH receptor antibodies in long-term euthyroid postmenopausal women with treated Graves’ disease. Thyroid Research. 2013; 6:e11. 268. Madsen M, Fisker S, U Feldt-Rasmussen, Andreassen M, Kristensen L Ø, Orskov H & Jørgensen J O L. Circulating levels of pegvisomant and endogenous growth hormone during prolonged pegvisomant therapy in patients with acromegaly. Clinical Endocrinology. 2014; 80:92-100. 269. Watt T, Grønvold M, Hegedüs L, Bonnema S J, Rasmussen Å K, U Feldt-Rasmussen & Bjorner J B.Pew items in the thyroid-related quality of life instrument ThyPRO exhibited differential item functioning. Quality of Life Research. 2014; 23:1. 270. Bliddal S, U Feldt-Rasmussen, Boas M, Faber J, Juul A, Larsen T K & Precht D H. Gestational- age-specific reference ranges from different laboratories misclassifies pregnant women’s thyroid status: comparison of two longitudinal prospective cohort studies. European Journal of Endocrinology. 2014; 170:329-339. 271. Delgrange E, Raverot G, Bex M, Burman P, Decoudier B, Devuyst F, U Feldt-Rasmussen, Andersen M & Maiter D. Giant prolactinomas in women. European Journal of Endocrinology. 2014; 170;31-38. 272. Prabakaran T, Birn H, Bibby B M, Regeniter A, Sørensen S S, U Feldt-Rasmussen, Nielsen R S & Christensen E. Long-term enzyme replacement therapy is associated with reduced proteinuria and preserved proximal tubular function in women with Fabry disease. Nephrology, dialysis, transplantation. 2014; 29:619-25. 273. Salomo L H, Laursen A H, Reiter N & U Feldt-Rasmussen: Myxoedema coma: an almost forgotten, yet still existing cause of multiorgan failure. B M J Case Reports. 2014; pii: bcr2013203223 274. Klose M, Stochholm K, Janukonyté J, Lehman Christensen L, Frystyk J, Andersen M, Laurberg P M, Sandahl Christiansen J & U Feldt-Rasmussen. Prevalence of posttraumatic growth hormone deficiency is highly dependent on the diagnostic set-up – results from The Danish National study on posttraumatic hypopituitarism. The Journal of Clinical Endocrinology and Metabolism. 2014; 99:101-110. 275. Cramon P, Rasmussen Å K, Bonnema S J, Bjorner J B, U Feldt-Rasmussen, Groenvold M, Hegedüs L & Watt T. Development and implementation of PROgmatic: A clinical trial management system for pragmatic muliti-centre trials, optimised for electronic data capture and patient-reported outcomes. Clinical Trials (London, England). 2014; 11:344-354. 276. Winther K H, Watt T, Bjørner J B, Cramon P, U Feldt-Rasmussen, Gluud C, Gram J, Groenvold M, Hegedüs L, Knudsen N, Rasmussen Å K & Bonnema S. The chronic autoimmune thyroiditis quality of life selenium trial (CATALYST): study protocol for a randomized controlled trail. Trials. 2014; 15:115.

34 277. Tritos N A, Johannsson G, Korbonits M, Miller K K, U Feldt-Rasmussen, Yuen K C J, King D, Mattsson A F, Jonsson P J, Koltowska-Haggstrom M, Klibanski A & Biller B M K. Effects of long- term growth hormone replacement in adults with growth hormone deficiency folloing cure of acromegaly: a KIMS analysis. The Journal of Clinical Endocrinology and Metabolism. 2014; 99:2018-2029. 278. Pickering L, Jennum P, Gammeltoft S, Poulsgaard L, U Feldt-Rasmussen & Klose M. Sleep-wake and melatonin pattern in craniopharyngioma patient. European Journal of Endocrinology. 2014; 170:873-884. 279. Giovanella L, Clark P M, Chiovato L, Duntas L, Elisei R, U Feldt-Rasmussen, Leenhardt L, Luster M, Schalin-Jäntti C, Schott M, Seregni E, Rimmele H, Smit J & Verburg F A. Thyroglobulin measurement using highly sensitive assays in patients with differentiated thyroid cancer: a clinical position paper. European Journal of Endocrinology. 2014; 171: R33-46. 280. Bové K B, Watt T, Vogel A, Hegedüs L, Bjoerner J B, Groenvold M, Bonnema S J, Rasmussen Å K & U Feldt-Rasmussen. Anxiety and depression are more prevalent in patients with Graves ’ disease than in patients with nodular goitre. European Thyroid Journal. 2014; 3:173-178. 281. Watt T, Barbesino G, Bjorner J B, Bonnema S J, Bukvic B, Drummond R, Groenvold M, Hegedüs L, Kantzer V, Lasch K E, Marcocci C, Mishra A, Netea-Maier R, Ekker M, Paunovic I, Quinn T J, Rasmussen Å K, Russell A, Sabaretnam M, Smit J, Törring O, Zivaljevic V & U Feldt-Rasmussen. Cross-cultural validity of the thyroid-specific quality-of-life patient-reported outcome measure, ThyPRO. Quality of Life Research. 2014; 24(3):769-780. 282. Watt T, Groenvold M, Deng N, Gandek B, U Feldt-Rasmussen, Rasmussen Å K, Hegedüs L, Bonnema S & Bjorner J. Confirmatory factor analysis of the thyroid-related quality of life questionnaire ThyPRO. Health and Quality of Life Outcomes. 2014; 12:126. 283. Watt T, Cramon P, Hegedüs L, Bjorner J B, Bonnema S J, Rasmussen Å K, U Feldt-Rasmussen & Groenvold M. The Thyroid-Related Quality of Life Measure ThyPRO Has Good Responsiveness and Ability to Detect Relevant Treatment Effects. The Journal of Clinical Endocrinology and Metabolism. 2014; 99:3708-3717. 284. Nexø M A, Watt T, Cleal B, Hegedüs L, Bonnema S J, Rasmussen Å K, U Feldt-Rasmussen & Bjorner J B. Exploring the Experiences of People With Hypo- And Hyperthyroidism. Qualitative Health Research. 2015;25(7):945-953 285. Giovanella L, U Feldt-Rasmussen, Verburg F A, Grebe S K, Plebani M & Clark P M. Thyroglobulin measurement by highly sensitive assays: focus on laboratory challenges. Clinical Chemistry and Laboratory Medicine. 2015;53(9):1301-1314 286. Lassen T, Friis-Hansen L, Rasmussen A K, Knigge U & U Feldt-Rasmussen: Primary hyperparathyroidism in young people. When shold we perform genetic testing for multiple endocrine neoplasia 1(MEN-1). The Journal of Clinical Endocrinology and Metabolism. 2014; 99:3983-3987. 287. Nexo M A, Watt, T, Bonnema S J, Hegedüs L, Rasmussen Å K, U Feldt-Rasmussen & Bjorner J B. Thyroid-specific questions on work ability showed known-groups validity among Danes with thyroid diseases. Quality of Life Research. 2015;24:1615-1627 288. Cramon P, Bonnema S J, Bjorner J B, Ekholm O, U Feldt-Rasmussen, Frendl D M, Groenvold M, Hegedüs L, Rasmussen Å K & Watt T. Quality of life in patients with benign non-toxis goiter: impact of disease, treatment response, and comparison with the general population. Thyroid. 2015; 25;284-291. 289. Nexø, M. A., Watt, T., Cleal, B., Hegedüs, L., Bonnema, S. J., Rasmussen, Å. K., U Feldt- Rasmussen, U. & Bjorner, J. B. Exploring the Experiences of People With Hypo- and Hyperthyroidism. Qualitative Health Research. 2015;25(7):945-953.

35 290. Giovanella, L., U Feldt-Rasmussen, Verburg, F. A., Grebe, S. K., Plebani, M. & Clark, P. M. Thyroglobulin measurement by highly sensitive assays: focus on laboratory challenges. Clin Chem Lab Med. 2015;53(9):1301-1314 291. Nexo, M. A., Watt, T., Bonnema, S. J., Hegedüs, L., Rasmussen, Å. K., U Feldt-Rasmussen. & Bjorner, J. B. Thyroid-specific questions on work ability showed known-groups validity among Danes with thyroid diseases. Qual Life Res. 2015;24(7):1615-1627. 292. Klose, M., Stochholm, K., Janukonyté, J., Christensen, L. L., Cohen, A., Wagner, A., Laurberg, P., Christiansen, J. S., Andersen, M. & U Feldt-Rasmussen. Patient reported out-come in posttraumatic pituitary deficiency: results from The Danish National Study on Posttraumatic Hypopituitarism. European Journal of Endocrinology 2015;172(6):753-762. 293. Marina, D., Klose, M., Nordenbo, A., Liebach, A. & U Feldt-Rasmussen. Early endocrine alterations reflect prolonged stress and relate to one-year functional outcome in patients with severe brain injury. Eur J Endocrinol. 2015;172:813-822. 294. Bengtsson, D., Schrøder, H. D., Andersen, M., Maiter, D., Berinder, K., U Feldt-Rasmussen, Rasmussen, Å. K., Johannsson, G., Hoybye, C., van der Lely, A. J., Petersson, M., Ragnarsson, O. & Burman, P. Long-Term Outcome and MGMT as a Predictive Marker in 24 Patients With Atypical Pituitary Adenomas and Pituitary Carcinomas Given Treatment With Temozolomide. The Journal of clinical endocrinology and metabolism. 2015; 100:1689-1698. 295. Andreassen, Mikkel; Toft, Birgitte Grønkær; Feltoft, Claus Larsen; Hitz, Mette Friberg; Rasmussen, Åse Krogh; U Feldt-Rasmussen:Three cases of acth-producing pheochromocytoma- full hormonal workup in patients with an adrenal mass may be crucial for correct management. AACE clinical case reports, 2015; 1: e170-e174. 296. Fledelius, Hans C; Jelveh Sandfeld, Lisbeth; Rasmussen, Åse Krogh; Madsen , Christoffer V; U Feldt-Rasmussen: Ophthalmic experience over 10 years in an observational nationwide Danish cohort of Fabry patients with access to enzyme replacement. Acta Ophthalmologica 2015; 93: 256- 264. 297. Hansen, Juliana Frohnert; Nielsen, Claus Henrik; Brorson, Marianne Møller; Frederiksen, Hanne; Hartoft-Nielsen, Marie-Louise; Rasmussen, Åse Krogh; Bendtzen, Klaus; U Feldt-Rasmussen: Influence of phthalates on in vitro innate and adaptive immune responses. P L o S One 2015; 10, e0131168. 298. Watt, Torquil; Barbesino, Giuseppe; Bjorner, Jakob Bue; Bonnema, Steen Joop; Bukvic, Branka; Drummond, Russell; Groenvold, Mogens; Hegedüs, Laszlo; Kantzer, Valeska; Lasch, Kathryn E; Marcocci, Claudio; Mishra, Anjali; Netea-Maier, Romana; Ekker, Merel; Paunovic, Ivan; Quinn, Terence J; Rasmussen, Åse Krogh; Russell, Audrey; Sabaretnam, Mayilvaganan; Smit, Johannes; Törring, Ove; Zivaljevic, Vladan; U Feldt-Rasmussen:Cross-cultural validity of the thyroid- specific quality-of-life patient-reported outcome measure, ThyPRO. Qual Life Res. 2015;24(3):769- 780 299. Marina, Djordje; Burman, Pia; Klose, Marianne; Casar-Borota, Olivera; Luque, Raúl M; Castaño, Justo P; U Feldt-Rasmussen:Truncated somatostatin receptor 5 may modulate therapy response to somatostatin analogues--Observations in two patients with acromegaly and severe headache. Growth Horm IGF Res. 2015;25(5):262-267 300. Watt, Torquil; Bjorner, Jakob Bue ; Groenvold, Mogens; Cramon, Per; Winther, Kristian Hillert; Hegedüs, Laszlo; Bonnema, Steen Joop; Rasmussen, Åse Krogh; Ware, John E; U Feldt- Rasmussen: Development of a Short Version of the Thyroid-Related Patient-Reported Outcome ThyPRO. Thyroid 2015; 25: 1069-1079. 301. Bliddal, Sofie; Boas, Malene; Hilsted, Linda; Friis-Hansen, Lennart; Tabor, Ann; U Feldt- Rasmussen: Thyroid function and autoimmunity in Danish pregnant women after an iodine

36 fortification program and associations with obstetric outcomes. European Journal of Endocrinology 2015; 173: 709-718. 302. Korsholm, Kirsten; U Feldt-Rasmussen; Granqvist, Henrik; Højgaard, Liselotte; Bollinger, Birgit ; Rasmussen, Aase K; Law, Ian. Positron Emission Tomography and Magnetic Resonance Imaging of the Brain in Fabry Disease : A Nationwide, Long-Time, Prospective Follow-Up.P L o S One 2015; 10: e0143940. 303. Rasmussen MH, Janukonyté J, Klose M, Marina D, Tanvig M, Nielsen LF, Andersen M, U Feldt- Rasmussen, Christiansen JS. Reversible albumin-binding GH possesses a potential once-weekly treatment profile in adult growth hormone deficiency. The Journal of Clinical Endocrinology and Metabolism 2016; 101(3):988-998. 304. Diederichsen SZ, Darkner S, Chen X, Johannesen A, Pehrson S, Hansen J, U Feldt-Rasmussen: Svendsen JH. Short-term amiodarone treatment for atrial fibrillation after catheter ablation induces a transient thyroid dysfunction: Results from the placebo-controlled, randomized AMIO-CAT trial. European journal of internal medicine. 2016; 33:36-41. 305. *Germain DP, Hughes DA, Nicholls K, Bichet DG, Giugliani R, Wilcox WR, Feliciani C, Shankar SP, Ezgu F, Amartino H, Bratkovic D, U Feldt-Rasmussen, Nedd K, Sharaf El Din U, Lourenco CM, Banikazemi M, Charrow J, Dasouki M, Finegold D, Giraldo P, Goker-Alpan O, Longo N, Scott CR, Torra R, Tuffaha A, Jovanovic A, Waldek S, Packman S, Ludington E, Viereck C, Kirk J, Yu J, Benjamin ER, Johnson F, Lockhart DJ, Skuban N, Castelli J, Barth J, Barlow C, Schiffmann R. Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat. The New England Journal of Medicine. 2016;375(6):545-555* Impact factor 79.26. 306. Rasmussen, Michael Højby; Janukonyté, Jurgita; Klose, Marianne; Marina, Djordje; Tanvig, Mette; Nielsen, Lene F; Höybye, Charlotte; Andersen, Marianne; U Feldt-Rasmussen; Christiansen, Jens Sandahl. Reversible albumin-binding GH possesses a potential once-weekly treatment profile in adult growth hormone deficiency. The Journal of Clinical Endocrinology and Metabolism, 04.01.2016, s. jc20151991. 307. Frohnert, Juliana; Boas, Malene; Møller Brorson, Marianne; Frederiksen, Hanne; Hartoft-Nielsen, Marie-Louise; Krogh Rasmussen, Åse; Main, Katharina M; U Feldt-Rasmussen: Migration of phthalates on culture plates - an important challenge to consider for in vitro studies. Scand J Clin Lab Invest. 2016;76(2):165-171 308. Dal J, U Feldt-Rasmussen, Andersen M, Kristensen LØ, Laurberg P, Pedersen L o.a. Acromegaly incidence, prevalence, complications and long-term prognosis: a nationwide cohort study. European Journal of Endocrinology. 2016 sep;175(3):181-90. 309. Winther KH, Cramon P, Watt T, Bjorner JB, Ekholm O, U Feldt-Rasmussen o.a. Disease-Specific as Well as Generic Quality of Life Is Widely Impacted in Autoimmune Hypothyroidism and Improves during the First Six Months of Levothyroxine Therapy. P L o S One. 2016;11(6): e0156925. 310. Mynster Kronborg T, Frohnert Hansen J, Nielsen CH, Ramhøj L, Frederiksen M, Vorkamp K U Feldt-Rasmussen o.a. Effects of the Commercial Flame Retardant Mixture DE-71 on Cytokine Production by Human Immune Cells. P L o S One. 2016;11(4):e0154621. 311. Montagna G, Imperiali M, Agazzi P, D'Aurizio F, Tozzoli R, U Feldt-Rasmussen o.a. Hashimoto's encephalopathy: A rare proteiform disorder. Journal of Autoimmunity. 2016 maj;15(5):466-76. 312. Rasmussen SL, Rejnmark L, Ebbehøj E, U Feldt-Rasmussen, Rasmussen ÅK, Bjorner JB o.a. High Level of Agreement between Electronic and Paper Mode of Administration of a Thyroid- Specific Patient-Reported Outcome, ThyPRO. European Thyroid Journal. 2016 mar;5(1):65-72. 313. Frohnert Hansen J, Brorson MM, Boas M, Frederiksen H, Nielsen CH, Lindström ES, Hofman- Bang J, Hartoft-Nielsen ML, Frisch T, Main KM, Bendtzen K, Rasmussen ÅK, U Feldt-

37 Rasmussen: Phthalates Are Metabolised by Primary Thyroid Cell Cultures but Have Limited Influence on Selected Thyroid Cell Functions In Vitro. P L o S One. 2016;11(3):e0151192. 314. Cramon P, Winther KH, Watt T, Bonnema SJ, Bjorner JB, Ekholm O, U Feldt-Rasmussen o.a. Quality-of-Life Impairments Persist Six Months After Treatment of Graves' Hyperthyroidism and Toxic Nodular Goiter: A Prospective Cohort Study. Thyroid 2016;26(8):1010-1018. 315. Madsen CV, Bundgaard H, Rasmussen ÅK, Sørensen SS, Petersen JH, Køber L, U Feldt- Rasmussen, Petri H. Echocardiographic and clinical findings in patients with Fabry disease during long-term enzyme replacement therapy: a nationwide Danish cohort study. Scandinavian cardiovascular journal 2017;51(4):207-216. 316. Berglund A, Olsen M, Andersen M, Nielsen EH, U Feldt-Rasmussen, Kistorp C, Gravholt CH, Stochhholm K. Evaluation of ICD-10 algorithms to identify hypopituitary patients in the Danish National Patient Registry. Clinical Epidemiology. 2017;9:75-82. 317. Adalsteinsdottir B, Palsson R, Desnick RJ, Gardarsdottir M, Teekakirikul P, Maron M, Appelbaum E, Neisius U, Maron BJ, Burke MA, Chen B, Pagant S, Madsen CV, Danielsen R, Arngrimsson R, U Feldt-Rasmussen, Seidman JG, Seidman CE, Gunnarsson GT. Fabry Disease in Families With Hypertrophic Cardiomyopathy: Clinical Manifestations in the Classic and Later-Onset Phenotypes. Circ Cardiovascular Genetics.2017;10(4):e001639. 318. Mathiesen JS, Kroustrup JP, Vestergaard P, Stochholm K, Poulsen PL, Rasmussen ÅK, U Feldt- Rasmussen, Gaustadnes M, Ørntoft TF, Rossing M, Nielsen FC, Albrechtsen A, Brixen K, Godballe C, Frederiksen AL. Founder Effect of the RETC611Y Mutation in Multiple Endocrine Neoplasia 2A in Denmark: A Nationwide Study. Thyroid. 2017;27(12):1505-1510. 319. Mathiesen JS, Kroustrup JP, Vestergaard P, Stochholm K, Poulsen PL, Rasmussen ÅK, U Feldt- Rasmussen, Gaustadnes M, Ørntoft TF, van Overeem Hansen T, Nielsen FC, Brixen K, Godballe C, Frederiksen AL. Distribution of RET Mutations in Multiple Endocrine Neoplasia 2 in Denmark 1994-2014: A Nationwide Study. Thyroid 2017;27(2):215-23. 320. Borresen SW, Klose M, Baslund B, Rasmussen ÅK, Hilsted L, Friis-Hansen L, Hansen A, Hetland ML, Lydolph MC, U Feldt-Rasmussen: Adrenal insufficiency is seen in more than one-third of patients during ongoing low-dose prednisolone treatment for rheumatoid arthritis. European Journal of Endocrinology 2017;177(4):287-295. 321. Resende de Paiva C, Grønhøj C, U Feldt-Rasmussen, von Buchwald C. Association between Hashimoto's Thyroiditis and Thyroid Cancer in 64,628 Patients. Frontiers in Oncology. 2017; 7:e53. 322. Astradsson A, Munck Af Rosenschöld P, U Feldt-Rasmussen, Poulsgaard L, Wiencke AK, Ohlhues L, Engelholm SA, Broholm H, Hansen Møller E, Klose M, Roed H, Juhler M. Visual outcome, endocrine function and tumor control after fractionated stereotactic radiation therapy of craniopharyngiomas in adults: findings in a prospective cohort. Acta Oncologica (Stockholm, Sweden). 2017;56(3):415-421. 323. Hasholt L, Ballegaard M, Bundgaard H, Christiansen M, Law I, Lund AM, Norremolle A, Krogh Rasmussen A, Ravn K, Tumer Z, Wibrand F, U Feldt-Rasmussen: The D313Y variant in the GLA gene - no evidence of a pathogenic role in Fabry disease. Scandinavian Journal of Clinical and Laboratory Investigation. 2017;77(8):617-621 324. Kronborg TM, Hansen JF, Rasmussen ÅK, Vorkamp K, Nielsen CH, Frederiksen M, Hofman-Bang J, Hahn CH, Ramhøj L, U Feldt-Rasmussen: The flame retardant DE-71 (a mixture of polybrominated diphenyl ethers) inhibits human differentiated thyroid cell function in vitro. P L o S One. 2017;12(6):e0179858. 325. Hughes DA, Nicholls K, Shankar SP, Sunder-Plassmann G, Koeller D, Nedd K, Vockley G, Hamazaki T, Lachmann R, Ohashi T, Olivotto I, Sakai N, Deegan P, Dimmock D, Eyskens F, Germain DP, Goker-Alpan O, Hachulla E, Jovanovic A, Lourenco CM, Narita I, Thomas M,

38 Wilcox WR, Bichet DG, Schiffmann R, Ludington E, Viereck C, Kirk J, Yu J, Johnson F, Boudes P, Benjamin ER, Lockhart DJ, Barlow C, Skuban N, Castelli JP, Barth J, U Feldt-Rasmussen: Oral pharmacological chaperone migalastat compared with enzyme replacement therapy in Fabry disease: 18-month results from the randomised phase III ATTRACT study. Journal of medical genetics. 2017;54(4):288-96. 326. Pickering L, Klose M, U Feldt-Rasmussen, Jennum P. Polysomnographic findings in craniopharyngioma patients. Sleep and Breathing. 2017;21(4):975-982. 327. Hadjigeorgiou GF, Lund EL, Poulsgaard L, U Feldt-Rasmussen, Rasmussen ÅK, Wegener M, Fugleholm K. Intrachiasmatic abscess caused by IgG4-related hypophysitis. Acta Neurochirurgica. 2017;159(11):2229-2233. 328. Barington M, Brorson MM, Hofman-Bang J, Rasmussen ÅK, Holst B, U Feldt-Rasmussen: Ghrelin-mediated inhibition of the TSH-stimulated function of differentiated human thyrocytes ex vivo PLoS One. 2017;12(9):e0184992. 329. Prahm KP, U Feldt-Rasmussen, Vissing J. Human growth hormone stabilizes walking and improves strength in a patient with dominantly inherited calpainopathy. Neuromuscular disorders. 2017;27(4):358-362. 330. Mathiesen JS, Kroustrup JP, Vestergaard P, Madsen M, Stochholm K, Poulsen PL, Rasmussen AK, U Feldt-Rasmussen: Schytte S, Pedersen HB, Hahn CH, Bentzen J, Gaustadnes M, Ørntoft TF, Hansen TVO, Nielsen FC, Brixen K, Frederiksen AL, Godballe C. Incidence and prevalence of multiple endocrine neoplasia 2B in Denmark: a nationwide study. Endocrine-Related Cancer. 2017;24(7):L39-L42. 331. Bliddal S, Boas M, Hilsted L, Friis-Hansen L, Juul A, Larsen T, Tabor A, Faber J, Precht DH, U Feldt-Rasmussen: Increase in thyroglobulin antibody and thyroid peroxidase antibody levels, but not preterm birth-rate, in pregnant Danish women upon iodine fortification. European Journal of Endocrinology. 2017;176(5):603-612. 332. Johannsson G, U Feldt-Rasmussen, Håkonsson IH, Biering H, Rodien P, Tahara S, Toogood A, Rasmussen MH; REAL 2 Study Group. Safety and convenience of once-weekly somapacitan in adult GH deficiency: a 26-week randomized, controlled trial. European Journal of Endocrinology. 2018;178(5):491-499. 333. Andreassen M, Juul A, U Feldt-Rasmussen, Jørgensen N. Semen quality in patients with pituitary disease and adult-onset hypogonadotropic hypogonadism. Endocrine Connections. 2018;7(4):523- 533. 334. Dal J, Klose M, Heck A, Andersen M, Kistorp C, Nielsen EH, Bollerslev J, U Feldt-Rasmussen, Jørgensen JOL. Targeting either GH or IGF-I during somatostatin analogue treatment in patients with acromegaly: a randomized multicentre study. European Journal of Endocrinology. 2018 jan;178(1):67-76. 335. Mintziori G, Watt T, Veneti S, Panagiotou A, Pournaras DJ, U Feldt-Rasmussen, Rasmussen ÅK, Hegedüs L, Bonnema SJ, Bjorner JB, Kita M, Goulis DG. ThyPROgr: the Greek edition of the ThyPRO questionnaires for patients with benign thyroid diseases. Hormones. 2018;17(1):107-112. 336. Harsløf M, Knudsen AD, Benfield T, Nordestgaard BG, U Feldt-Rasmussen, Nielsen SD. No evidence of increased risk of thyroid dysfunction in well-treated people living with HIV. AIDS (London, England). 2018;32(15):2195-2199. 337. Sawicka-Gutaj N, Ruchala M, U Feldt-Rasmussen, Rasmussen ÅK, Hegedüs L, Bonnema SJ, Groenvold M, Bjorner JB, Watt T. Patients with Benign Thyroid Diseases Experience and Impaired Sex Life. Thyroid 2018;28(10):1261-1269. 338. Ebbehoj A, Jacobsen SF, Trolle C, Robaczyk MG, Rasmussen ÅK, U Feldt-Rasmussen, Thomsen RW, Poulsen PL, Stochholm K, Søndergaard E. Pheochromocytoma in Denmark during 1977-2016:

39 validating diagnosis codes and creating a national cohort using patterns of health registrations. Clinical Epidemiology. 2018;10:683-695. 339. Boesen VB, Christoffersen T, Watt T, Borresen SW, Klose M, U Feldt-Rasmussen: PlenadrEMA: effect of dual-release versus conventional hydrocortisone on fatigue, measured by ecological momentary assessments: a study protocol for an open-label switch pilot study. BMJ Paediatrics Open 2018;8(1):e019487. 340. Krause M, Frederiksen H, Sundberg K, Jørgensen FS, Jensen LN, Nørgaard P, Jørgensen C, Ertberg P, Petersen JH, U Feldt-Rasmussen, Juul A, Drzewiecki KT, Skakkebaek NE, Andersson AM. Maternal exposure to UV filters and associations to maternal thyroid hormones and IGF-I/IGFBP3 and birth outcomes. Endocrine Connections. 2018;7(2):334-346. 341. Petersen TG, Andersen A-MN, Uldall P, Paneth N, U Feldt-Rasmussen, Tollånes MC, Strandberg- Larsen K. Maternal thyroid disorder in pregnancy and risk of cerebral palsy in the child: a population-based cohort study. BMC Pediatrics. 2018;18(1):181. 342. Schiffmann R, Bichet DG, Jovanovic A, Hughes DA, Giugliani R, U Feldt-Rasmussen, Shankar SP, Barisoni L, Colvin RB, Jennette JC, Holdbrook F, Mulberg A, Castelli JP, Skuban N, Barth JA, Nicholls K. Migalastat improves diarrhea in patients with Fabry disease: clinical-biomarker correlations from the phase 3 FACETS trial. Orphanet Journal of Rare Diseases. 2018;13(1):68. 343. Krzyzanowska-Mittermayer K, Mattsson AF, Maiter D, U Feldt-Rasmussen, Camacho-Hübner C, Luger A, Abs R. New neoplasm during GH replacement in adults with pituitary deficiency following malignancy- a KIMS analysis. The Journal of clinical endocrinology and metabolism. 2018;103(2):523-31. 344. Boesen VB, U Feldt-Rasmussen, Bjorner JB, Cramon P, Groenvold M, Nygaard B, Rasmussen ÅK, Vilsbøll T, Watt T. How should thyroid-related quality of life be assessed? Recalled patient- reported outcomes compared with here-and-now measures. Thyroid 2018;28(12):1561-1570. 345. Wilcox WR, U Feldt-Rasmussen, Martins AM, Ortiz A, Lemay RM, Jovanovic A, Germain DP, Varas C, Nicholls K, Weidemann F, Hopkin RJ. Improvement of Fabry Disease-Related Gastrointestinal Symptoms in a Significant Proportion of Female Patients Treated with Agalsidase Beta: Data from the Fabry Registry. JIMD reports. 2018;38:45-51. 346. Mathiesen JS, Kroustrup JP, Vestergaard P, Stochholm K, Poulsen PL, Rasmussen ÅK, U Feldt- Rasmussen, Schytte S, Pedersen HB, Hahn CH, Bentzen J, Möller S, Gaustadnes M, Rossing M, Nielsen FC, Brixen K, Frederiksen AL, Godballe C. Incidence and prevalence of multiple endocrine neoplasia 2A in Denmark 1901-2014: a nationwide study. Clinical Epidemiology. 2018; 10:1479- 1487. 347. Mathiesen JS, Kroustrup JP, Vestergaard P, Stochholm K, Poulsen PL, U Feldt-Rasmussen, Danish Thyroid Cancer Group (DATHYRCA). Incidence and prevalence of sporadic and hereditary MTC in Denmark 1960-2014: a nationwide study. Endocrine Connections. 2018;7(6):829-839. 348. Loeb J, U Feldt-Rasmussen, Madsen CV, Vogel A. Cognitive Impairments and Subjective Cognitive Complaints in Fabry Disease: A Nationwide Study and Review of the Literature. JIMD reports. 2018;41:73-80. 349. Li Z-M, Hernandez-Moreno D, Main KM, Skakkebæk NE, Kiviranta H, Toppari J, U Feldt- Rasmussen, Shen H, Schramm KW, De Angelis M. Association of In Utero Persistent Organic Pollutant Exposure with Placental Thyroid Hormones. Endocrinology. 2018;159(10):3473-3481. 350. Dal J, Leisner MZ, Hermansen K, Farkas DK, Bengtsen M, Kistorp C, Nielsen EH, Andersen M, U Feldt-Rasmussen, Dekkers OM, Sørensen HT, Jørgensen JOL. Cancer Incidence in Patients With Acromegaly: A Cohort Study and Meta-Analysis of the Literature. The Journal of clinical endocrinology and metabolism. 2018;103(6):2182-2188. 351. Boesen VB, Nissen SB, Groenvold M, Bjorner JB, Hegedüs L, Bonnema SJ, Rasmussen ÅK, U Feldt-Rasmussen, Watt T. Conversion of standard retrospective patient-reported outcomes to

40 momentary versions: cognitive interviewing reveals varying degrees of momentary compatibility. Quality of life research 2018;27(4):1065-1076. 352. Joustra SD, Gu C, Rohling JHT, Pickering L, Klose M, Hu K, Scheer FA, U Feldt-Rasmussen, Jennum PJ, Pereira AM, Biermasz NR, Meijer JH. Decrease in scale invariance of activity fluctuations with aging and in patients with suprasellar tumors. Chronobiology International. 2018;35(3):368-377 353. Li Z-M, Giesert F, Vogt-Weisenhorn D, Main KM, Skakkebæk NE, Kiviranta H, Toppari J, U Feldt-Rasmussen, Shen H, Schramm KW, De Angelis M. Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry. Journal of Chromatography. 2018; 1534:85-92 354. Boronat M, González-Lleó A, Rodríguez-Pérez C, U Feldt-Rasmussen, López-Plasencia Y, Rasmussen ÅK Alberiche-Ruano MP, Hegedüs L, Alvarado-Martel D, Bonnema SJ, Marrero- Arencibia D, Groenvold M, Bjorner JB, Watt T. Adaptation and cross-cultural validation of the Spanish version of the Thyroid-Related Quality-of-Life Patient-Reported Outcome questionnaire. Endocrinologia, Diabetes y Nutricion. 2018;65(9):500-507. 355. Madsen CV, Christensen EI, Nielsen R, Mogensen H, Rasmussen ÅK, U Feldt-Rasmussen: Enzyme Replacement Therapy During Pregnancy in Fabry Patients: Review of Published Cases of Live Births and a New Case of a Severely Affected Female with Fabry Disease and Pre-eclampsia Complicating Pregnancy. JIMD reports. 2019;44:93-101. 356. Mathiesen JS, Kroustrup JP, Vestergaard P, Poulsen PL, Rasmussen ÅK, U Feldt-Rasmussen, Schytte S, Londero SC, Pedersen HB, Hahn CH, Bentzen J, Möller S, Gaustadnes M, Rossing M, Nielsen FC, Brixen K, Godballe C. Replication of newly proposed TNM staging system for medullary thyroid carcinoma: a nationwide study. Endocrine Connections. 2019;8(1):1-7. 357. Madsen CV, Granqvist H, Petersen JH, Rasmussen ÅK, Lund AM, Oturai P, Sørensen SS U Feldt- Rasmussen: Age-related renal function decline in Fabry disease patients on enzyme replacement therapy: a longitudinal cohort study. Nephrology, dialysis, transplantation. 2019; 34(9):1525-1533 358. Mathiesen JS, Kroustrup JP, Vestergaard P, Poulsen PL, Stochholm K, Rasmussen ÅK, U Feldt- Rasmussen, Schytte S, Londero SC, Pedersen HB, Hahn CH, Bentzen J, Möller S, Gaustadnes M, Rossing M, Nielsen FC, Brixen K, Frederiksen AL, Godballe C. Survival and long-term biochemical cure in medullary thyroid carcinoma in Denmark 1997-2014: A nationwide study. Thyroid 2019; 29(3):368-377 359. Hughes DA, Nicholls K, Sunder-Plassmann G, Jovanovic A, U Feldt-Rasmussen, Schiffmann R, Giugliani R, Jain V, Viereck C, Castelli JP, Skuban N, Barth JA, Bichet DG.Safety of switching to Migalastat from enzyme replacement therapy in Fabry disease: Experience from the Phase 3 ATTRACT study. Am J Med Genet A. 2019;179(6):1069-1073. 360. Astradsson A, Munck Af Rosenschöld P, Poulsgaard L, Ohlhues L, Engelholm SA, U Feldt- Rasmussen, Marsh R, Roed H, Juhler M. Cerebral infarction after fractionated stereotactic radiation therapy of benign anterior skull base tumors. Clin Transl Radiat Oncol. 2019;15:93-98. 361. Mathiesen JS, Kroustrup JP, Vestergaard P, Stochholm K, Poulsen PL, Rasmussen ÅK, U Feldt- Rasmussen, Schytte S, Londero SC, Pedersen HB, Hahn CH, Bentzen J, Möller S, Gaustadnes M, Rossing M, Nielsen FC, Brixen K, Frederiksen AL, Godballe C; Danish Thyroid Cancer Group (DATHYRCA). Completeness of RET testing in patients with medullary thyroid carcinoma in Denmark 1997-2013: a nationwide study. Clin Epidemiol 2019; 11: 93-99. 362. Frimodt-Møller KE, Møllegaard Jepsen JR, U Feldt-Rasmussen, Krogh J. Hippocampal volume, cognitive functions, depression, anxiety, and quality of life in patients with Cushing's syndrome. J Clin Endocrinol Metab. 2019 pii: jc.2019-00749. [Epub ahead of print]

41 363. Valentin A, Borresen SW, Rix M, Elung-Jensen T, Sørensen SS, U Feldt-Rasmussen: Adrenal insufficiency in kidney transplant patients during low-dose prednisolone therapy: a cross-sectional case-control study. Nephrol Dial Transplant. 2019 [Epub ahead of print] 364. *Consortium on thyroid and pregnancy-Study Group on Preterm birth, Korevaar TIM, Derakhshan A, Taylor PN, Meima M, Chen L, Bliddal S, Carty DM, Meems M, Vaidya B, Shields B, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan C, Boucai L, Vafeiadi M, Grineva EN, Tkachuck AS, Pop VJM, Vrijkotte TG, Guxens M, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Murcia M, Lu X, Mukhtar S, Delles C, U Feldt-Rasmussen, Nelson SM, Alexander EK, Chaker L, Männistö T, Walsh JP, Pearce EN, Steegers EAP, Peeters RP. Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta- analysis. JAMA. 2019 Aug 20;322(7):632-641.* Impact factor 47.46 365. *Bliddal S, U Feldt-Rasmussen, Rasmussen ÅK, Kolte AM, Hilsted LM, Christiansen OB, Nielsen CH, Nielsen HS Thyroid Peroxidase Antibodies and Prospective Live Birth Rate: A Cohort Study of Women with Recurrent Pregnancy Loss. Thyroid. 2019 [Epub ahead of print]* Impact factor 7.78 366. Dal J, Nielsen EH, Feldt- Rasmussen U, Andersen M, Feltoft CL, Vestergaard P o.a. Disease Control and Gender Predict the Socioeconomic Effects of Acromegaly: A Nationwide Cohort Study. The Journal of clinical endocrinology and metabolism. 2020; 105(9). https://doi.org/10.1210/clinem/dgaa405 367. Boesen VB, Bjorner JB, Groenvold M, Cramon PK, Rasmussen AK, Watt T, Feldt-Rasmussen U. Ecological momentary assessments (EMAs) did not improve responsiveness of patient-reported outcomes on quality of life. Journal of Clinical Epidemiology. 2020; 125: 138-147. 368. Main AM, Rossing M, Borgwardt L, Grønkær Toft B, Rasmussen ÅK, Feldt-Rasmussen U. Genotype-phenotype associations in PPGLs in 59 patients with variants in SDHX genes. Endocrine Connections. 2020; 9: 793-803. 369. Derakhshan A, Peeters RP, Taylor PN, Bliddal S, Carty DM, Meems M, Feldt-Rasmussen U o.a. Association of maternal thyroid function with birthweight: a systematic review and individual- participant data meta-analysis. The Lancet Diabetes and Endocrinology. 2020; 8: 501-510. 370. Wanner C, Feldt-Rasmussen U, Jovanovic A, Linhart A, Yang M, Ponce E o.a. Cardiomyopathy and kidney function in agalsidase beta-treated female Fabry patients: a pre-treatment vs. post- treatment analysis. ESC Heart Failure. 2020; 7: 825-834. 371. Martino G, Catalano A, Agostino RM, Bellone F, Morabito N, Lasco CG, Feldt-Rasmussen U o.a. Quality of life and psychological functioning in postmenopausal women undergoing aromatase inhibitor treatment for early breast cancer. PLoS One. 2020 apr 26;15(3):e0230681. https://doi.org/10.1371/journal.pone.0230681 372. Effraimidis G, Rasmussen ÅK, Bundgaard H, Sørensen SS, Feldt-Rasmussen U. Is the alpha- galactosidase A variant p.Asp313Tyr (p.D313Y) pathogenic for Fabry disease? A systematic review. Journal of Inherited Metabolic Disease. 2020 apr 4;e-pub. https://doi.org/10.1002/jimd.12240 373. Andreassen M, Juul A, Feldt-Rasmussen U, Jørgensen N. Semen quality in hypogonadal acromegalic patients. Pituitary. 2020; 23: 160-166. 374. Borresen SW, Thorgrimsen TB, Jensen B, Hilsted L, Bartels EM, Feldt-Rasmussen U o.a. Adrenal insufficiency in prednisolone-treated patients with polymyalgia rheumatica or giant cell arteritis- prevalence and clinical approach. Rheumatology (Oxford, England). 2020 feb 7. https://doi.org/10.1093/rheumatology/keaa011 375. Boesen VB, Feldt-Rasmussen U, Bjorner JB, Cramon PK, Groenvold M, Rasmussen ÅK o.a. Shorter recall period for the thyroid-related patient-reported outcome measure ThyPRO did not

42 change the accuracy as evaluated by repeated momentary measurements. Thyroid 2020; 30:185- 191. 376. Adhikari KB, Rohde M, Velschow S, Feldt-Rasmussen U, Johannesen J, Johnsen AH. Fluispotter, a novel automated and wearable device for accurate volume serial dried blood spot sampling. Bioanalysis. 2020; 12: 665-681. 377. Buschard K, Holm LJ, Feldt-Rasmussen U. Insulin Independence in Newly Diagnosed Type 1 Diabetes Patient following Fenofibrate Treatment. Case reports in medicine. 2020;2020:6865190. https://doi.org/10.1155/2020/6865190 378. Dal J, Nielsen EH, Klose M, Feldt-Rasmussen U, Andersen M, Vang S o.a. Phenotypic and genotypic features of a large kindred with a germline AIP variant. Clinical Endocrinology. 2020; 93: 146-153. 379. Hoybye C, Burman P, Feldt-Rasmussen U, Hey-Hadavi J, Aydin F, Camacho-Hubner C o.a. Change in baseline characteristics over 20 years of adults with growth hormone (GH) deficiency on GH replacement therapy. European Journal of Endocrinology. 2020; 181: 629-638.

Review Articles

1. U Feldt-Rasmussen: Serum thyroglobulin and thyroglobulin autoantibodies in thyroid diseases. Pathogenic and diagnostic aspects. Allergy 1983; 38(6):369-387 (DISPUTATS) 2. K Bech, H Bliddal, U Feldt-Rasmussen, E Kappelgaard, H Nielsen Heterogeneity of autoimmune thyroiditis. Allergy 1984; 39(4):239-247 3. H Bliddal, K Bech, U Feldt-Rasmussen, M Høier-Madsen, B Thomsen, H Nielsen Humoral autoimmune manifestation in subacute thyroiditis. Allergy 1985; 40(8):599-604 4. U Feldt-Rasmussen, A K Rasmussen Serum thyroglobulin (Tg) in presence of thyroglobulin autoantibodies (TgAb). Clinical and methodological relevance of the interaction between Tg and TgAb in vitro and in vivo. J Endocrinol Invest 1985; 8(6):571-576 5. U Feldt-Rasmussen, M Høier-Madsen Tyreoglobulin-autoantistoffer. Nyere metodologiske og prognostiske aspekter. Ugeskr Laeger 1985; 147(12):1030-1034 6. U Feldt-Rasmussen, D Glinoer, J Orgiazzi Reassessment of antithyroid drug therapy of Graves' disease. Annu Rev Med 1993; 44 323-334 7. A K Rasmussen, U Feldt-Rasmussen, K Bendtzen The effect of interleukin-1 on the thyroid gland. Autoimmunity 1993; 16(2):141-148 8. M Blichert-Toft, C L Mollerup, U Feldt-Rasmussen, H Daugaard, U H Engel Primaer hyperparatyreoidisme. En underdiagnosticeret sygdom i Danmark? Ugeskr Laeger 1993; 155(11):765-769 9. U Feldt-Rasmussen, D Glinoer, J Orgiazzi Revurdering af antityreoid medicinsk behandling af Graves' sygdom. Ugeskr Laeger 1995; 157(1):25-29 10. U Feldt-Rasmussen, A K Rasmussen Mutationer i tyreotropinreceptoren som årsag til thyreoideadysfunktion. Ugeskr Laeger 1996; 158(1):64-66 11. U Feldt-Rasmussen: Analytical and clinical performance goals for testing autoantibodies to thyroperoxidase, thyroglobulin, and thyrotropin receptor. Clin Chem 1996; 42(1):160-163 12. U Feldt-Rasmussen, A K Rasmussen, T Zimmermann-Belsing, M L Hartoft-Nielsen Pathogenic and clinical aspects of Graves' disease. Exp Clin Endocrinol Diabetes 1999; 107 S71-74 13. U Feldt-Rasmussen: Antithyroid drug therapy: predictive parameters. 1999; 93 53-55 14. A K Rasmussen, M L Hartoft-Nielsen, U Feldt-Rasmussen: Models to study the pathogenesis of thyroid autoimmunity. Biochimie 1999; 81(5):511-515 15. M Lange, A K Rasmussen, U Feldt-Rasmussen: Behandling af langvarig kritisk sygdom med hypothalamushormoner? Ugeskr Laeger 2001; 163(32):0-4210

43 16. A K Rasmussen, U Feldt-Rasmussen: Autoimmun thyroiditis--en infektionssygdom? Ugeskr Laeger 2002; 164(50):5911-5915 17. U Feldt-Rasmussen, A K Rasmussen, H Mersebach, K M Rosenberg, L Hasholt, S A Sorensen Fabry disease--a metabolic disorder with a challenge for endocrinologists? Hormone Research 2002; 58(6):259-265 18. M Boas, U Feldt-Rasmussen, N E Skakkebaek, K M Main Environmental chemicals and thyroid function. European Journal of Endocrinology 2006; 154(5):599-611 19. T Watt, M Groenvold, A K Rasmussen, S J Bonnema, L Hegedüs, J B Bjorner, U Feldt- Rasmussen: Quality of life in patients with benign thyroid disorders. A review. European Journal of Endocrinology 2006; 154(4):501-510 20. M C Klose, A Juul, L Poulsgaard, M Kosteljanetz, J Brennum, U Feldt-Rasmussen Hypofyseinsufficiens efter hovedtraumer. Ugeskr Laeger 2007; 169(3):211-213 21. U Feldt-Rasmussen: Treatment of hypothyroidism in elderly patients and in patients with cardiac disease. Thyroid 2007; 17(7):619-624 22. U Feldt-Rasmussen: Thyroid and leptin. Thyroid 2007; 17(5):413-419 23. J O L Jørgensen, U Feldt-Rasmussen, J Frystyk, J-W Chen, L Ø Kristensen, C Hagen, H Ørskov Medicinsk kombinationsbehandling af akromegali med somatostatinanalog og en vaeksthormon- receptorantagonist. Ugeskr Laeger 2007; 169(10):911-913 24. U Feldt-Rasmussen: Bridging provocative tests and clinical manifestations of growth hormone deficiency in adults. Hormone Research 2007; 68 57-58 25. J O L Jørgensen, U Friis Feldt-Rasmussen, M Andersen, L Ø Kristensen, P Laurberg, J Weeke Akromegali: nye behandlingsprincipper. Ugeskr Laeger 2007; 169(10):904-906 26. U Feldt-Rasmussen: Interactions between growth hormone and the thyroid gland - with special reference to biochemical diagnosis. Curr Med Chem 2007; 14(26):2783-2788 27. T Watt, U Feldt-Rasmussen, A K Rasmussen, L Hegedüs, S J Bonnema, M Grønvold, J B Bjørner Måling af helbredsrelateret livskvalitet hos patienter med thyroideasygdomme. Ugeskr Laeger 2008; 170(10):850-852 28. M Klose, U Feldt-Rasmussen: Does the type and severity of brain injury predict hypothalamo- pituitary dysfunction? Does post-traumatic hypopituitarism predict worse outcome? Pituitary 2008; 11(3):255-261 29. Oliver Klefter, U Feldt-Rasmussen: Is increase in bone mineral content caused by increase in skeletal muscle mass/strength in adult patients with growth hormone (GH) treated GH deficiency? A systematic literature analysis. European Journal of Endocrinology 2009; 0 0 30. U Feldt-Rasmussen: Is the treatment of subclinical hypothyroidism beneficial? Nat Clin Pract Endocrinol Metab 2009; 5(2):86-87 31. Boas M, Main KM, U Feldt-Rasmussen: Environmental chemicals and thyroid function: an update. Curr Opin Endocrinol Diabetes Obes. 2009; 16:385-91. 32. U Feldt-Rasmussen & A K Rasmussen. Autoimmunity in differentiated thyroid cancer: significance and related clinical problems. Hormones. 2010; 9:109-17. 33. U Feldt-Rasmussen, S Bliddal, Å K Rasmussen, M Boas, L Hilsted & K Main. Challenges in interpretation of thyroid function tests in pregnant women with autoimmune thyroid disease. Journal of thyroid research. 2011; 598712. 34. Hartoft-Nielsen, M-L., Boas, M., Bliddal, S., Rasmussen, A. K., Main, K. & U Feldt-Rasmussen: Do Thyroid Disrupting Chemicals influence Foetal Development during Pregnancy? Journal of Thyroid Research. 2011; 342189. 35. U Feldt-Rasmussen: Fabry disease and early stroke. Stroke Research and Treatment. 2011; 615218.

44 36. S Bliddal, Å K Rasmussen, K Sundberg, V Brocks, U Feldt-Rasmussen & Medscape. Antithyroid drug-induced fetal goitrous hypothyroidism. Nature reviews. Endocrinology. 2011; 7:396-406. 37. M Boas, U Feldt-Rasmussen, & K M Main. Thyroid effects of endocrine disrupting chemicals. Molecular and Cellular Endocrinology. 2012; 355:240-8. 38. S Dinsen, B Baslund, M Klose, Å K Rasmussen, L Friis-Hansen, L Hilsted & U Feldt-Rasmussen: Why glucocoriticoid withdrawal may sometimes be as dangerous as the treatment itself. European Journal of Internal Medicine. 2013; 24:714-20. 39. F A Verburg, M Luster, C Cupini, L Chiovato, L Duntas, R Elisei, U Feldt-Rasmussen, H Rimmele, E Seregni, J W A Smit, C Theimer, & L Giovanella. Implications of thyrogilobulin antibody positivity in pationts with differentiated thyroid cancer: a clinical position statement. Thyroid. 2013; 23:1211-25. 40. Frohnert, J., Bendtzen, K., Boas, M., Frederiksen, H., Nielsen, C. H., Rasmussen, Å. K. & U Feldt- Rasmussen: Influence of phthalates on cytokine production in monocytes and macrophages: a systematic review of experimental trials. P L o S One. 2015. E0120083. 41. Biegstraaten, Marieke; Arngrímsson, Reynir; Barbey, Frederic; Boks, Lut; Cecchi, Franco; Deegan, Patrick B; U Feldt-Rasmussen; Geberhiwot, Tarekegn; Germain, Dominique P; Hendriksz, Chris; Hughes, Derralynn A; Kantola, Ilkka; Karabul, Nesrin; Lavery, Christine; Linthorst, Gabor E; Mehta, Atul; van de Mheen, Erica; Oliveira, João P; Parini, Rossella; Ramaswami, Uma; Rudnicki, Michael; Serra, Andreas; Sommer, Claudia; Sunder-Plassmann, Gere; Svarstad, Einar; Sweeb, Annelies; Terryn, Wim; Tylki-Szymanska, Anna; Tøndel, Camilla; Vujkovac, Bojan; Weidemann, Frank; Wijburg, Frits A; Woolfson, Peter; Hollak, Carla E M. Recommendations for initiation and cessation of enzyme replacement therapy in patients with Fabry disease : the European Fabry Working Group consensus document. I: Orphanet Journal of Rare Diseases, Vol. 10, 2015, s. 36. 42. Dinsen, Stina; Klose, Marianne; Rasmussen, Åse Krogh; U Feldt-Rasmussen: Adrenal Insufficiency Caused by Locally Applied Glucocorticoids-Myth or Fact?. Current Medicinal Chemistry, Vol. 22, Nr. 23, 2015, s. 2801-9. 43. Svensson, Camilla Kara; U Feldt-Rasmussen; Backer, Vibeke. Fabry disease, respiratory symptoms, and airway limitation - a systematic review. European Clinical Respiratory Journal, Vol. 2, 2015, s. e2. 44. Klose, Marianne; U Feldt-Rasmussen: Hypopituitarism in Traumatic Brain Injury-A Critical Note. Vol. 4, Nr. 7, 14.07.2015, s. 1480-9 45. U Feldt-Rasmussen, Klose M. Central hypothyroidism and its role for cardiovascular risk factors in hypopituitary patients. Endocrine. 2016 okt;54(1):15-23. 46. Bliddal S, Nielsen CH, U Feldt-Rasmussen: Recent advances in understanding autoimmune thyroid disease: the tallest tree in the forest of polyautoimmunity. F1000Research. 2017;6:e1776. Tilgængelig fra, DOI: 10.12688/f1000research.11535.1 47. Bliddal S, Dinsen S, U Feldt-Rasmussen: Thyroid Autoimmunity and Function after Treatment with Biological Antirheumatic Agents in Rheumatoid Arthritis. Frontiers in Endocrinology. 2017;8:e179. Tilgængelig fra, DOI: 10.3389/fendo.2017.00179 48. U Feldt-Rasmussen, Bliddal S, Rasmussen ÅK, Boas M, Hilsted L, Main K. Corrigendum to "Challenges in Interpretation of Thyroid Function Tests in Pregnant Women with Autoimmune Thyroid Disease". Journal of thyroid research. 2017;2017:e4324130. 49. U Feldt-Rasmussen, Klose M, Benvenga S. Interactions between hypothalamic pituitary thyroid axis and other pituitary dysfunctions. Endocrine. 2018 sep 6. 50. Benvenga S, Klose M, Vita R, U Feldt-Rasmussen: Less known aspects of central hypothyroidism: Part 1 - Acquired etiologies. Journal of Clinical and Translational Endocrinology. 2018;14:25-33.

45 51. Benvenga S, Klose M, Vita R, U Feldt-Rasmussen: Less known aspects of central hypo- thyroidism: Part 2 - Congenital etiologies. Journal of Clinical and Translational Endocrinology. 2018;14:5-11. 52. Persani L, Brabant G, Dattani M, Bonomi M, U Feldt-Rasmussen, Fliers E o.a. 2018 European Thyroid Association (ETA) Guidelines on the Diagnosis and Management of Central Hypothyroidism. European Thyroid Journal. 2018 okt;7(5):225-237. 53. *Klose M, U Feldt-Rasmussen: Chronic endocrine consequences of traumatic brain injury - what is the evidence? Nature reviews. Endocrinology. 2018 jan;14(1):57-62*. Impact factor 24.64 54. Wanner C, Arad M, Baron R, Burlina A, Elliott PM, U Feldt-Rasmussen o.a. European expert consensus statement on therapeutic goals in Fabry disease. Molecular Genetics and Metabolism. 2018 jul;124(3):189-203. 55. Germain DP, Arad M, Burlina A, Elliott PM, Falissard B, U Feldt-Rasmussen o.a. The effect of enzyme replacement therapy on clinical outcomes in female patients with Fabry disease - A systematic literature review by a European panel of experts. Molecular Genetics and Metabolism. 2019. 56. Benvenga S, U Feldt-Rasmussen, Bonofiglio D, Asamoah E.Nutraceutical Supplements in the Thyroid Setting: Health Benefits beyond Basic Nutrition. Nutrients. 2019 Sep 13;11(9). pii: E2214. doi: 10.3390/nu11092214. Review. 57. Feldt-Rasmussen U. Hashimoto's thyroiditis as a risk factor for thyroid cancer. Current Opinion in Endocrinology, Diabetes and Obesity. 2020 aug 6. ttps://doi.org/10.1097/MED.0000000000000570

Book Chapters

1. U Feldt-Rasmussen: Serum thyroglobulin and thyroglobulin antibodies in thyroid disorders. Thyroid Diseases. Ed. Christian Beckers. 1982, Pergamon Press France , Paris, France 2. U Feldt-Rasmussen, L Hegedüs, JM Hansen & H Perrild: Beziehung zwischen Schildrüsenvolumen und serum thyreoglobulin bei langzeitssuppression durch L-trijodthyronin bei patienten mit diffuser struma. In: Schilddrüse 1983. Eds: C.R. Pickardt, H. Schleusener, B Weunheimer 1985, Thieme, Stuttgart, Germany 3. U Feldt-Rasmussen, L Hegedüs, H Perrild, JM Hansen, M Blichert-Toft & J Date: Serum thyroglobulin in non-toxic goitre and response to therapy. In: Current Topics in Thyroid Autoimmunity Eds: D. Doniach, Horst Schleusener, Balthasar Weinheimer. 1984, Georg Thieme Verlag, Stuttgart, Germany. 4. L Hegedüs, S Karstrup, D Veiergang B Jacobsen, L Skovsted & U Feldt-Rasmussen: Is cigarette smoking goitrogenic? In: Current Topics in Thyroid Autoimmunity Eds: D. Doniach, Horst Schleusener, Balthasar Weinheimer. 1984, Georg Thieme Verlag, Stuttgart, Germany 5. JP Kampmann, JM Hansen, L Hegedüs, K Lühdorf, H Perrild & U Feldt-Rasmussen: Increased thyroid volume during phenytoin and carbamazepine treatment. In: Current Topics in Thyroid Autoimmunity. Eds: D. Doniach, Horst Schleusener, Balthasar Weinheimer. 1984, Georg Thieme Verlag, Stuttgart, Germany 6. J Petersen & U Feldt-Rasmussen: Impact of T helper and T suppressor cells on the production of anti-thyroglobulin antibodies in autoimmune thyroiditis. In: The Thyroid and Autoimmunity. Eds: H.A. Drexhage, W.M. Wiersinga. 1986, Excerpta Medica, Amsterdam, Netherlands 7. K Bech, U Feldt-Rasmussen, Å Krogh Rasmussen, M Blichert-Toft, H Bliddal, S Faurschou & D Marushak: Thyroid antibodies in endocrine ophtalmopathy. In: The Thyroid and Autoimmunity. Eds: H.A. Drexhage, W.M. Wiersinga. 1986, Excerpta Medica, Amsterdam, Netherlands 8. Å Krogh Rasmussen, U Feldt-Rasmussen, HS Hansen, J Witten & P Winkel: Thyroglobulin determinations in follow-up of patients with differentiated thyroid carcinoma. In: Thyroglobulin and

46 Thyroglobulin Antibodies in the Follow-up of Thyroid Cancer and Endemic Goitre. Eds Michael Hüfner, Christoph Reiners. 1987, Georg Thieme Verlag, Stuttgart, Germany 9. U Feldt-Rasmussen & M Schlumberger: European collaborative study evaluating serum thyroglobulin standards. In: Thyroglobulin and Thyroglobulin Antibodies in the Follow-up of Thyroid Cancer and Endemic Goitre. Eds Michael Hüfner, Christoph Reiners. 1987, Georg Thieme Verlag, Stuttgart, Germany 10. U Feldt-Rasmussen, M Blichert-Toft, J Date, JM Hansen, L Hegedüs, H Perrild & P Hyltoft: Serum thyroglobulin in non-toxic goitre. Relation to thyroid volume determination, drugs and non- thyroid diseases. In: Thyroglobulin and Thyroglobulin Antibodies in the Follow-up of Thyroid Cancer and Endemic Goitre. Eds Michael Hüfner, Christoph Reiners. 1987, Georg Thieme Verlag, Stuttgart, Germany 11. K Bech, U Feldt-Rasmussen, H Bliddal, M H¢ier-Madsen, B Thomsen & H Nielsen: Persistence of autoimmune reactions during recovery of subacute thyroiditis. In: Thyroid Autoimmunity. Eds: A Pinchera, S.H. Ingbar, J.M. McKenzie, G.F. Fenzi. 1987, Plenum Press, New York, USA 12. BK Pedersen, U Feldt-Rasmussen, H Perrild, J Mølholm Hansen & T Christensen: Natural killer cell activity in Hashimoto, Graves disease and euthyroid exophtalmos. In: Thyroid Autoimmunity. Eds: A Pinchera, S.H. Ingbar, J.M. McKenzie, G.F. Fenzi. 1987, Plenum Press, New York, USA 13. Å Krogh Rasmussen, U Feldt-Rasmussen, K Bech, S Poulsen & K Bendtzen: The influence of interleukin-1 on the function of human thyroid cells. In: Thyroid Autoimmunity. Eds: A Pinchera, S.H. Ingbar, J.M. McKenzie, G.F. Fenzi. 1987, Plenum Press, New York, USA. 14. U Feldt-Rasmussen, B Rasmusson, K Bech, L Hegedüs, M Høier-Madsen & H Perrild: Serum thyroid autoantibodies in patients with brest cancer. In: Thyroid Autoimmunity. Eds: A Pinchera, S.H. Ingbar, J.M. McKenzie, G.F. Fenzi. 1987, Plenum Press, New York, USA 15. K Bech, H Bliddal, U Andersen, Å Krogh Rasmussen, H Sand Hansen, U Feldt-Rasmussen & J Witten: Thyroid autoantibodies in thyroid cancer. In: Thyroid Autoimmunity. Eds: A Pinchera, S.H. Ingbar, J.M. McKenzie, G.F. Fenzi. 1987, Plenum Press, New York, USA 16. K Bech, U Feldt-Rasmussen, H Bliddal, C Bregengaard, B Danneskiold-Sams¢e, S Husby, K Johansen, C Kierkegaard, T Friis, K Siersbæk-Nielsen & H Nielsen: Thyroid stimulating immunoglobulins without evidence of in vivo thyroid stimulation in some non-thyroid autoimmune diseases. In: Thyroid Autoimmunity. Eds: A Pinchera, S.H. Ingbar, J.M. McKenzie, G.F. Fenzi. 1987, Plenum Press, New York, USA 17. Å Krogh Rasmussen, L Kayser, K Bech, K Bendtzen, U Feldt-Rasmussen & H Perrild: Differential effect of interleukin-1 on cultured rat and human thyroid cells. In: FRTL-5 Today. Eds: F.S. Ambesi-Impiombato, H. Perrild. 1989, Elsevier Science Publisher B.V., Amsterdam, Netherlands 18. L Kayser, K Bech, Å Krogh-Rasmussen, U Feldt-Rasmussen & H Perrild: DNA determination in the evaluation of FRTL-5 cell growth. In: FRTL-5 Today. Eds: F.S. Ambesi-Impiombato, H. Perrild. 1989, Elsevier Science Publisher B.V., Amsterdam, Netherlands 19. Å Krogh Rasmussen, L Kayser, K Bech, U Feldt-Rasmussen, H Perrild, K Bendtzen: Interleukin 6: A pathogenic factor in autoimmune thyroid disease. In: Autoimmune Thyroiditis. Eds: W.A. Scherbaum, U. Bogner, B. Weinheimer, G.F. Botazzo 1991, Springer Verlag, Berlin, Germany 20. L Kayser, Å Krogh Rasmussen, K Bech, U Feldt-Rasmussen, H Perrild, K Bendtzen: Endotoxins do not mimick the effect of interleukin-1 in secondary culture of human thyroid cells. In: Autoimmune Thyroiditis. Eds: W.A. Scherbaum, U. Bogner, B. Weinheimer, G.F. Botazzo. 1991, Springer Verlag, Berlin, Germany 21. U Feldt-Rasmussen, M Høier-Madsen, NG Rasmussen, L Hegedüs, PJ Hornnes, H Perrild: Comparison between microsomal antibodies by immune fluorescence and anti-TPO antibodies in

47 healthy individuals and thyroid autoimmune disease. In: Autoimmune Thyroiditis. Eds: W.A. Scherbaum, U. Bogner, B. Weinheimer, G.F. Botazzo 1991, Springer Verlag, Berlin, Germany 22. U Feldt-Rasmussen, H Schleusener, P Carayon: Do thyrotropin receptor antibodies predict relapse after antithyroid drug treatment of Graves disease hyperthyroidism? In: 80 years of Hashimoto disease. Eds: S Nagataki, T Mori, K Torizuka 1993, Excerpta medica, Elsevier Science Publishers, Amsterdam, Netherlands 23. U Feldt-Rasmussen, Å Krogh Rasmussen, L Kayser, M Svenson, M Diamant, K Bech, K Bendtzen: A role of interleukin-1 and interleukin-6 in thyroiditis? In: 80 years of Hashimoto disease. Eds: S Nagataki, T Mori, K Torizuka. 1993, Excerpta medica, Elsevier Science Publishers, Amsterdam, Netherlands 24. U Feldt-Rasmussen: Iodine intake and prevalence and types of thyroid carcinoma. In: The thyroid and iodine: In: The Thyroid and Iodine Eds J Nauman, D Glinoer, LE Bravermann. 1996, Schattauer Verlag, Stuttgart, Germany 25. U Feldt-Rasmussen: Thyroid. In: Clinical Pharmacology. Eds: Cesare Sirtori, Jochen Kuhlmann, Bosidar Vrhovac, Marcus M Reidenberg. 2000, McGraw-Hill International Ltd, Maidenhead, United Kingdom 26. U Feldt-Rasmussen: Prevalence and types of thyroid cancer as a function of iodine intake. In: The Thyroid and Environment. Eds: F Peter, W Wiersinga. 2000, Schattauer, Stuttgart, Germany 27. U Feldt-Rasmussen, Zimmermann-Belsing T, Rasmussen ÅK, Nygaard B, Carayon P. The development and clinical use of TRAb assays. Bronchocele Goiter 2000. In: Goitrogenesis upon the advent of the New Millenium. Ed Leonidas H Duntas. 2001, Beta Medical Publishers Ltd, Athens, Greece 28. U Feldt-Rasmussen: Thyroiditis. In: Conn. Eds: Robert E Rakel, Edward T Bope. 2004, Saunders, Philadelphia, USA 29. Henriette Mersebach, Aase Krogh Rasmussen, U Feldt-Rasmussen: Body composition - methods and effect of growth hormone. In: Growth Hormone Deficiency in Adults. Eds: Roger Abs, U Feldt-Rasmussen. 2004, Oxford PharmaGenesis, Oxford, United Kingdom 30. Medical Dictionary, Gyldendals Røde Ordbøger, Ed: Bengt I. Lindskog , Specialist advisor and writer in Endocrinology, 1. edition Gyldendags Boghandel, Nordisk Forlag A/S, Copenhagen, Denmark, 2004 31. U Feldt-Rasmussen: Treatment of hypothyroidism in patients with cardiac disease. In: The thyroid and cardiovascular risk.Eds: M Derwahl, L Duntas, S Butz. 2005, Georg Thieme Verlag, New York, Germany 32. Rasmussen ÅK, U Feldt-Rasmussen: Growth hormone replacement therapy in adults - responsiveness related to life quality. The somatotrophic axis in brain function. Ed: Fred Nyberg. 2006, Elsevier Academic press, London, United Kingdom 33. U Feldt-Rasmussen Rasmussen ÅK. Thyroid Hormone Transport and action. Diseases of the Thyroid in Childhood and Adolescence. Eds: GE Krassas, SA Rivkees, W Kiss. 2007, Karger, Basel, Switzerland 34. U Feldt-Rasmussen: Which Thyroid Function Tests Should We be Measuring during Gestation. In: The Thyroid and Reproduction. Eds: John Lazarus, Valdis Pirags. 2009, Thieme, Stuttgart - New York, Germany 35. U Feldt-Rasmussen & Mathiesen E R. Endocrine disorders in pregnancy: physiological and hormonal aspects of pregnancy. 2011. Best Practice & Research: Clinical Endocrinology & Metabolism.

48 36. U Feldt-Rasmussen & Sørensen P S. Akut medicin og neurologi. Medicin. Lærebog i medicin. Baslund B, Feldt-Rasmussen U, Kastrup J & Soelberg Sørensen P. (red.). 1. udg. 2012 FADL's Forlag, Kap. 13. 37. Baslund B & U Feldt-Rasmussen: Patient-læge forholdet. Medicin. Lærebog i medicin. Baslund B, Feldt-Rasmussen U, Kastrup J & Soelberg Sørensen P. (red.). 1. udg. FADL's Forlag, 2012; Kap. 1. 38. U Feldt-Rasmussen & Klose M C. Principper for endokrinologiske fundtionsundersøgelser. Medicin. Lærebog i medicin. Baslund B, Feldt-Rasmussen U, Kastrup J & Soelberg Sørensen P. (red.). 1. udg. FADL's Forlag, Vol. 1. 2012; Kap. 7.1. 39. U Feldt-Rasmussen & Klose M C. Sygdomme I Hypothalamus hypofyse. Medicin. Lærebog i medicin. Baslund B, Feldt-Rasmussen U, Kastrup J & Soelberg Sørensen P. (red.). 1. udg. FADL's Forlag, Vol. 1. 2012; Kap. 7.2. 40. U Feldt-Rasmussen & Tønnesen P. Søvnforstyrrelser hos patienter med medicinske sygdomme. Søvn. Selberg N. (red.). Munksgård Danmark. 2013; Kap. 13. 41. Dieperink H, Thiesson H, Egfjord M & U Feldt-Rasmussen: Arteriel hypertension. Medicin. Lærebog i medicin. Baslund, B., Feldt-Rasmussen, U., Kastrup, J. & Soelberg Sørensen, P. (red.). 1. udg. FADL's Forlag, Vol. 1. 2012; Kap. 6.6. 42. Klose M C & U Feldt-Rasmussen: Binyrernes sygdomme. Medicin. Lærebog i medicin. Baslund, B., Feldt-Rasmussen, U., Kastrup, J. & Soelberg Sørensen, P. (red.). 1. udg. FADL's Forlag, Vol. 1. 2012; Kap. 7.3. 43. Nielsen CH, Helweg-Larsen J, U Feldt-Rasmussen, Baslund B. Immunsystemet og den medicinske patient. I Baslund B, Feldt-Rasmussen U, Kastrup J, Sørensen PS, red., Medicin. København: FADL's Forlag. 2016. s. 748-765. 44. Baslund B, U Feldt-Rasmussen. Patient-Læge-Forholdet. I Baslund B, Feldt-Rasmussen U, Kastrup J, Soelberg Sørensen P, red., Medicin. Lærebog i medicin. 2 udg. Bind 1. FADL's Forlag. 2016. s. 18-22. 45. Klose MC, U Feldt-Rasmussen. Binyrernes Sygdomme. I Baslund B, Feldt-Rasmussen U, Kastrup J, Soelberg Sørensen P, red., Medicin. Lærebog i medicin. 2 udg. Bind 1. FADL'S FORLAG. 2017. s. 554-566. 46. U Feldt-Rasmussen, Mathiesen ER. Akut endokrinologi. I Akutbogen - for læger og sygeplejersker. 1 udg. Bind 1. Forfatterne og Munksgaard, København. 2017. s. 122-138. 47. U Feldt-Rasmussen, Klose MC, Andersen M. Principper for endokrinologiske funktionsundersøgelser. I Baslund B, Feldt-Rasmussen U, Kastrup J, Soelberg Sørensen P, red., Medicin. Lærebog i medicin. 2 udg. Bind 1. FADL'S FORLAG. 2017. s. 532-535. 48. U Feldt-Rasmussen, Klose M & Rasmussen ÅK. Diagnosis of Hypothyroidism. . In: Ilpo Huhtaniemi and Luciano Martini (Eds.), Encyclopedia of Endocrine Diseases, 2nd edition, vol. 4, pp. 604-607. Oxford: Academic Press. (2019) Tilgængelig fra doi:10.1016/B978-0-12-801238- 3.96008-2 49. U Feldt-Rasmussen, Klose M & Rasmussen ÅK. Causes of Hypothyroidism. In: Ilpo Huhtaniemi and Luciano Martini (Eds.), Encyclopedia of Endocrine Diseases, 2nd edition, vol. 4, pp. 600-603. Oxford: Academic Press. (2017) Tilgængelig fra doi:10.1016/B978-0-12-801238-3.96006-9 50. Effraimidis G & U Feldt-Rasmussen. Thyroiditis, Infectious and Subacute. In: Ilpo Huhtaniemi and Luciano Martini (Eds.), Encyclopedia of Endocrine Diseases, 2nd edition, vol. 4, pp. 737-746. Oxford: Academic Press. (2017) Tilgængelig fra doi:10.1016/B978-0-12-801238-3.96028-8 51. U Feldt-Rasmussen & Rasmussen ÅK. Drug Effects and Thyroid Function. In: Ilpo Huhtaniemi and Luciano Martini (Eds.), Encyclopedia of Endocrine Diseases, 2nd edition, vol.4, pp. 772-779. Oxford: Academic Press. (2018) Tilgængelig fra doi:10.1016/B978-0-12-801238-3.96002-1

49 52. Effraimidis G & U Feldt-Rasmussen. Hashimoto’s Thyroiditis. In: Ilpo Huhtaniemi and Luciano Martini (Eds.), Encyclopedia of Endocrine Diseases, 2nd edition, vol. 4, pp. 613-615. Oxford: Academic Press.e (2018) Tilgængelig fra doi:10.1016/B978-0-12-801238-3.96004-5 53. U Feldt-Rasmussen, Bliddal S & Nielsen CH. Thyroid Autoimmunity. In: Ilpo Huhtaniemi and Luciano Martini (Eds.), Encyclopedia of Endocrine Diseases, 2nd edition, vol. 4, pp. 636-650. Oxford: Academic Press. (2018) Tilgængelig fra doi:10.1016/B978-0-12-801238-3.96017-3 54. Jørgensen M B & U Feldt-Rasmussen. Thyroid Function and Depression. In: Ilpo Huhtaniemi and Luciano Martini (Eds.), Encyclopedia of Endocrine Diseases, 2nd edition, vol. 4, pp. 792-801. Oxford: Academic Press. (2018) Tilgængelig fra Doi:10.1016/B978-0-12-801238-3.96001-X 55. Bliddal, S., Nielsen, H.S & U Feldt-Rasmussen: Thyroid and Infertility. In: Ilpo Huhtaniemi and Luciano Martini (Eds.), Encyclopedia of Endocrine Diseases, 2nd edition, vol. 4, pp. 752-761. Oxford: Academic Press. (2019) Tilgængelig fra doi:10.1016/B978-0-12-801238-3.65222-4 56. U Feldt-Rasmussen and Giovanella L. Thyroglobulin and Tg antibodies. In: Luster M et al (Eds): The thyroid and its diseases. A comprehensive guide for the clinician. Springer AG: 2019; pp.655- 672. 57. U Feldt-Rasmussen: Laboratory measurement of thyroid related hormones, proteins and autoantibodies in serum. In: Werner and Ingbar’s The Thyroid: A fundamental and clinical text. 11th Edition. Eds. David Cooper & Peter Kopp 2019. In press

Other Publications

• Borresen SW, Thorgrimsen TB, Jensen B, Hilsted L, Bartels EM, Feldt-Rasmussen U o.a. Comment on: Adrenal insufficiency in prednisolone-treated patients with polymyalgia rheumatica or giant cell arteritis-prevalence and clinical approach: reply. Rheumatology (Oxford, England). 2020 aug 5. https://doi.org/10.1093/rheumatology/keaa239 • Körver S, U Feldt-Rasmussen, Svarstad E, Kantola I, Langeveld M. Oral Chaperone Therapy Migalastat for the Treatment of Fabry Disease: Potentials and Pitfalls of Real- World Data. Clin Pharmacol Ther. 2019 Jul 12. doi: 10.1002/cpt.1536. [Epub ahead of print] • U Feldt-Rasmussen, Emerson CH, Ross DS, Kopp PA, Pearce N. Thoughts on the Japanese and American Perspectives on Thyroid Storm. Thyroid. 2019 Jul 1. doi: 10.1089/thy.2019.0010. [Epub ahead of print] • Borresen SW, Laursen T, Jensen B, Hilsted L, Bartels EM, U Feldt-Rasmussen o.a. Adrenal insufficiency during prednisolone treatment in patients with polymyalgia rheumatica or giant cell arteritis - Prevalence and clinical approach. Endocrine Abstracts. 2018;56. P19. • U Feldt-Rasmussen. Growth Hormone Deficiency—Controversies in the Clinical Management in Adults. Journal of the Endocrine Society. 2016 apr 1;206-209. • U Feldt-Rasmussen, Borresen SW, Klose M. Er en behandling uden tilstrækkelig evidens altid sikrest at undlade? Ugeskrift for laeger. 2018 nov 26;180(48). • U Feldt-Rasmussen. Behandles danske kvinder med lavt stofskifte korrekt under graviditet? Vol. 177, Nr. 32, 03.08.2015, s. V66933. • U Feldt-Rasmussen. Increased risk of thyroid autoimmunity in rheumatoid arthritis. I: Endocrine, Vol. 50, Nr. 1, 09.2015, s. 4-5. • Bliddal S, Rasmussen Å K, Sundberg K & U Feldt-Rasmussen. Careful assessment of maternal thyroid function can prevent cases of fetal goitrous hypothyroidism. Fetal Diagnosis and Therapy. 2013; 34:66-7.

50 • Jarzab B & U Feldt-Rasmussen. Introduction to European comments on “Medullary Thyroid Cancer: management guidelines of the American Thyroid Association”. Thyroid Research. 2013; 6:1. • U Feldt-Rasmussen. Subclinical hypothyroidism in pregnancy: to treat or nor to treat. Endocrine. 2013; 44: 455-456. • U Feldt-Rasmussen & Emerson C H. Further thoughts on the diagnosis and diagnostic criteria for thyroid storm. Thyroid. 2012; 22:1094-5. • Bliddal S, Rasmussen Å K, Sundberg K, Brocks V & U Feldt-Rasmussen. Comment on "Intrauterine diagnosis and management of fetal goiter: a case report". Journal of Clinical Ultrasound. 2011; 39:276-8. • Luger A, U Feldt-Rasmussen, Abs R, Gaillard R C, Buchfelder M, Trainer P & Brue T. Lessons learned from 15 years of KIMS and 5 years of ACROSTUDY. Hormone Research in Paediatrics. 2011; 76; 33-8. • Stochholm K, Sunde L, Lisbeth Frederiksen A, Lihn A, Marie Vestergaard E, Løgstrup Poulsen P, Vestergaard P, Brixen K, Claes Eskildsen P, Rasmussen Å K, U Feldt- Rasmussen & Friis-Hansen L J. Multipel Endokrin Neoplasi. Klaringsrapport – 2011. Ugeskrift for Læger. 2011; 1-50 50. • U Feldt-Rasmussen: How to manage treatment of hypothyroidism in patients with cardiac disease. European Endocrine Disease 2007; 2: 83-84 • U Feldt-Rasmussen. Management of patients with differentiated thyroid cancer. European Endocrine Disease, 2007; 1: 70-72 • U Feldt-Rasmussen. What is the optimal follow-up strategy for patients with papillary thyroid microcarcinoma? Commentary. Nature Clinical Practice. Endocrinol and Metab 2006; 2:426-427. • U Feldt-Rasmussen. Characteristics of acromegaly from a single country registry in Spain. International Growth Monitor 2005; 15:23-4. • Michael B Ranke & U Feldt-Rasmussen (EDS): 6th KIGS/KIMS expert meeting on growth hormone and growth disorders. GHD during critical phases of life. Hormone Research 2003; 60: suppl 1:1 • U Feldt-Rasmussen, ÅK Rasmussen: Thyreoideacancer. Diagnostik og behandling. Månedsskrift for Praktisk Lægegerning 78: 2000; 1261-1266. • Rasmussen, ÅK, U Feldt-Rasmussen: Thyreoiditis. Diagnostik og behandling. Månedsskrift for Praktisk Lægegerning 78: 2000; 1395-1400 • U Feldt-Rasmussen, R Abs, KIMS Study Group. Characteristics of hypopituitary GHD patients previously treated for acromegaly and Cushing’s syndrome. In: GH replacement in adults. The first 5 years of KIMS. Eds: B-Å Bengtsson and JP Monson. Oxford PharmaGenesis (Oxford, UK) 2000; 156-164. • U Feldt-Rasmussen: Diagnose der Wachtumshormondefizienz bei Erwachsenen - Erfahrungen aus KIMS. In: Wachstumshormontherapie bei Erwachsenen mit Wachtumshormonmangel. Eds. C Wüster & P Kann. Ed J & J, Palatium Verlag, Mannheim, pp 17-25 • U Feldt-Rasmussen: The influence of growth hormone defiency on cardiac function during transition. Review. KIGS Biannual Report. Oxford 1999. 1999-02-26 • U Feldt-Rasmussen: Autoimmune thyreoideasygdomme ved graviditet og fødsel. Ugeskrift for Læger, Editorial, 1997;159, 1063 • U Feldt-Rasmussen: At være autoimmun. Morbus Addison foreningens medlemsblad. April 1997.

51 • JOL Jørgensen, JS Christensen, U Feldt-Rasmussen, C Hagen, LØ Kristensen, P Laurberg: Væksthormonmangel hos voksne. En klaringsrapport Ugeskrift for Læger nr 7 1997:1-3. • U Feldt-Rasmussen, ÅK Rasmussen: Mutationer i thyreotropinreceptoren som årsag til thyreoideadysfunktion. Ugeskrift for Læger, International research, 1996; 158: 64-65. • U Feldt-Rasmussen: Management of thyroid carcinoma. Thyroid International. Monografi. eds. G Hennemann & EP Krenning, Merck Pupl, Darmstadt. 1996: 1; 1-11. • M Blichert-Toft, U Feldt-Rasmussen: Thyroideakirurgi - hvem skal operere? Ugeskrift for Læger. Editorial, 1995; 157: 5969 • U Feldt-Rasmussen, M Høier-Madsen, K Bech, L Hegedüs, H Perrild, H Bliddal, B Danneskiold-Samsøe, B Rasmusson, NJ Kriegbaum, K Müller, A Schouboe, E Hippe: Anti- TPO antibodies in non-thyroid autoimmune disease. In: Thyroperoxidase and Thyroid Autoimmunity. Eds P Carayon & J Ruf. Colloque INSERM/John Libbey Eurotext 207:1990;297-301. • H Perrild, L Hegedüs, PC Båstrup, S Kastberg, U Feldt-Rasmussen, K Bech, M Høier- Madsen, L Kayser, A Møller, B Langvad Hansen: Thyroid autoimmunity in untreated and lithium treated patients with manic disease. In: The Thyroid Gland, Environment and Autoimmunity. Eds. HA Drexhage, JJM DeVijlder & WM Wiersinga. Elsevier Science Publ 1990;331-332. • H Perrild, L Kayser, J Mølholm Hansen, L Skovsted, U Feldt-Rasmussen, P Hyltoft Petersen. Serum sucro-sep-TSH, freies T4, tyreoglobulin und TBG nach 1 und 3 wochen behandlung mit betablokierenden medikamenten. In: Schilddrüse 1987. Ed. B Weinheimer. Georg Thieme Verlag, Stuttgart, New York 1989; 285-287. • U Feldt-Rasmussen, L Hegedüs, H Perrild, N Rasmussen, J M Hansen. Relationship between serum thyroglobulin, thyroid volume and serum TSH in healthy non-goitrous subjects and the relationship to seasonal variations in iodine intake. Thyroidology, 1989, Vol 1(No 3) 115-118 • S Bækkeskov & U Feldt-Rasmussen: Disease specificity of antibodies to the Mr 64000 human islet cell membrane autoantigen. Diabetes 37:1988;31A • H Perrild, U Feldt-Rasmussen, L Hegedüs & PC Baastrup: Serum thyroglobulin and thyroid volume during administration of lithium carbonate to healthy young subjects. In: Lithium: Inorganic Pharmacology and Psychiatric use. Ed. NJ Birch, IRL Press Ltd. 1988;183-184. • Book Review: U Feldt-Rasmussen: "PA Dahlberg, R Jansson, A Karlsson, K Westermark: Thyreoideasjukdomar i primärvården" Ugeskr for læger 149:1987;351-352 • K Bendtzen, Å Krogh Rasmussen, K Bech, U Feldt-Rasmussen & J Egeberg: Cytokines in autoimmunity. Immunology Today 8:1987;203 • K Bendtzen, Å Krogh Rasmussen, K Bech & U Feldt-Rasmussen: IL-1 and thyrocytes. N Engl J Med 317:1987; 247-248. Letter • AP Lange, U Feldt-Rasmussen, J Date, M Kern-Hansen. Thyroid function during Clomiphene treatment in anovulatory women. In: Per Aspera Ad Astra. Ed. SA Birkeland et al. Odense 1987;273-278. • U Feldt-Rasmussen, C Bregengaard, C Kierkegaard, H Bliddal, K Bech, B Danneskiold- Sams¢e, K Johansen, T Friis & K Siersbæk-Nielsen: Serum thyroglobulin and ultrasensitive TSH in normal persons and non-toxic goitre. In: Thyroid Function and Dysfunction. Modern Concepts. Ed A Carpi. ETS Editrice, Pisa 1987

52 • U Feldt-Rasmussen, Å Krogh-Rasmussen, H Sand Hansen, J Witten & M Schlumberger: Technical aspects of serum thyroglobulin measurements. In: Il Cancro Della Tiroide. Ed B Busnardo. Stampa "La Garangola" Padova 1987;75-78. • Å Krogh Rasmussen, K Bech, U Feldt-Rasmussen, S Poulsen, K Siersbæk-Nielsen, T Friis & K Bendtzen: The influence of interleukin-1 on the function of in vitro cultured human thyroid cells in monolayers. In: Advances in Thyroidology. Eds B Wenzel & P Scriba. Acta Endocrinol suppl 281:1987; 93-95. • SM McLachlan, R Jansson, P Thomson, M Blichert-Toft, U Feldt-Rasmussen, E Young & B Rees Smith: Distribution of thyroid autoantibodies among the IgG subclasses during fluctuations in total serum level. In: New Frontiers in Thyroidology. Ed G. Medeiros-Neto, Plenum Press, New York 1987; • J Date, M Blichert-Toft, U Feldt-Rasmussen & V Haas: Thyroid hormone changes in the 18 days following thyroidectomy for thyrotoxicosis. Scand J Clin Lab Invest 46:1986;133. • U Feldt-Rasmussen, HS Hansen, L Hegedüs, H Perrild, Å Krogh Rasmussen, M Schlumberger & J Witten: Serum thyroglobulin in thyroid carcinoma. Why the need for a standardization? In: Thyroid Cancer. Eds C Jaffiol & G Milhaud, Elsevier Science Publishers (Biomedical division) 1986;267-272. • Å Krogh Rasmussen, U Feldt-Rasmussen, J Date, J Witten, HS Hansen & H Funch- Rosenberg: Comparison of two assays for serum thyroglobulin and relation to thyroglobulin autoantibodies. In: Thyroid Cancer. Eds. C Jaffiol & G Milhaud. Elsevier Science Publishers (Biomedical Division) 1986;379-380. • C Kierkegaard, C Bregengaard, U Feldt-Rasmussen, K Bech & J Faber: Thyroid function testing. The Lancet i:1985;1455 • U Feldt-Rasmussen: Serum thyreoglobulin and thyroglobulin autoantibodies in thyroid diseases. Pathogenic and diagnostic aspects. Ugeskr for læger 1983 • U Feldt-Rasmussen: Ændringer i skjoldbruskkirtel proteiner ved stofskifte-sygdomme. Nyt fra Odense universitet 18:1983; 319-120 • U Feldt-Rasmussen, K Emmertsen & T Munkner: Differentiated thyroid carcinoma. Helsinki, 2-3.IX, 1983, Ugeskr for læger 146:1984;890-891 • U Feldt-Rasmussen, M H¢ier-Madsen, A Cambon de Mouzon, H Nielsen, M Thomsen, A Wiik & B Aasted: 5th European Immunology Meeting, Istanbul 1-4.VI.1982. Ugeskr for læger 144: 1982; 3173-3175. • U Feldt-Rasmussen & H Nielsen: Radioisotopic and reagent micro-analytical methods used in medical research and clinical diagnosis. Ugeskr for læger 139-1977;2684.

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