US 20090104295A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2009/0104295 A1 Kohno (43) Pub. Date: Apr. 23, 2009

(54) AGENT FOR HAIR GROWTH Publication Classification (76) Inventor: Kenji Kohno, Kanagawa (JP) (51) A6IRInt. Cl. 36/48 (2006.01) Correspondence Address: (52) U.S. Cl...... 424/757 THE WEBB LAW FIRM, P.C. (57) ABSTRACT 700 KOPPERS BUILDING, 436 SEVENTH AVENUE Thegrowth, whichA. SN, has excellents 1S lhair offer growth a IN effects E.but notfor S1de PITTSBURGH, PA 15219 (US) effects. The agent for hair growth of the present invention is (21) Appl. No.: 12AO63611 characterized by comprising a processed semi-mature Soy ppl. No.: 9 bean and/or a processed semi-mature soybean extracts and at 1-1. least one Substance selected from the group consisting of a (22)22) PCT Fled:1. Jun.un. 30,5U, 2006 processed Polygoni Multiflori Radix, processed Polygoni (86) PCT NO.: PCT/UP2006/31314.6 Multiflori Radix eXtracts, a processed Cynanchum bungei Decne or processed Cynanchum bungei Decne extracts, pref S371 (c)(1), erably further comprising Longan seed and/or Longan seed (2), (4) Date: Feb. 12, 2008 extracts as active ingredients. This agent for hair growth has no side effects when used externally or internally, it can (30) Foreign Application Priority Data notably improve hair growth within a short period of time; ranging from 6 to 12 weeks, can return hair to its normal hair Aug. 12, 2005 (JP) ...... 2005-261312 colour (for example from white to black) and can improve the Feb. 1, 2006 (JP) ...... 2006-024532 gloss of hair. Patent Application Publication Apr. 23, 2009 Sheet 1 of 5 US 2009/0104295 A1

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AGENT FOR HAR GROWTH 0008. It is therefore understandable, that I am consulted by a lot of patients with hair trouble who claim, that they have FIELD OF THE INVENTION never found a useful tonic. 0009 Patent document 1: JP 2001-238637 A 0001. This invention relates to a hair growth. More spe 0010 Patent document 2: JP 2002-053434 A cifically, this invention relates to a Substance which has an O011 Patent document 3: JP H08-127517 A excellent hair growth effect and is very safety. 0012 Patent document 4: JP H03-206019A 0013 Patent document 5: JP HO6-227.946A 0014 Patent document 6: JP HO6-100421 A BACKGROUND ART 0.015 Patent document 7:JP 2002-145732A 0002 Alopecia and thin hair are some of the most com DISCLOSURE OF THE INVENTION mon problems for mankind in the world. It is considered that various factors, for example, excessive activation of male Problem to be Solved by the Invention hormones, decrease of blood flow to the hair follicle and excessive secretion of sebum etc. may cause alopecia and thin 0016. The aim of this invention is to offer a novel agent for hair. These factors may be cause by aging, stress or/and life hair growth, which has excellent hair growth effects but not styles etc. side effects. 0003 Hair restorers, that are being suggested or put on the market today can, for example, consist of various herbal Means for Solving the Problem extracts, food extracts and vasodilator chemical compounds, 0017. The inventor of this invention found that the pro which can eliminate the cause of allopecia and thin hair. cessed semi-mature Soybean has significantly enhanced 0004 Up to now, it was suggested that isoflavone etc. effects on hair growth compared to the raw or fully matured contents in Soybean, had an effects on hair growth, therefore form. The processed semi-mature Soybean was obtained by Soybean was used as a component of a hair restorer. For removing the typical taste of the raw soybeans without pull example, in the patent document 1 (JP 2001-238637A), it was Verizing them by excessive heating. On completion of this disclosed that food components which contained extracts of invention, the inventor established that the processed semi millet and ginkgo leaf and isoflavones extracted from Soy mature Soybean plays an important role as a ingredient in the bean etc. have a positive effect on hair growth. In the patent agent for hair growth. document 2 (JP 2002-053434 A), it was disclosed that a hair 0018. In the agent for hair growth of the invention, the tonic contained isoflavone extracted from soybean and/or inventor combined the processed semi-mature Soybean and kudzu. And, in the patent document 3 (JPH08-127517A), it the processed Polygoni Multiflori Radix or the processed was disclosed that black soybean broth was included into an Cynanchum bungei Decne to increase synergy effect on hair external hair growth tonic and an external anti hair loss agent growth. In here, the processed Polygoni Multiflori Radix and as a compound. And, it was also suggested to apply herbal processed Cynanchum bungei Decne were made from raw medicines, such as Polygoni multiflori Radix etc. to a hair Polygoni Multiflori Radix and raw Cynanchum bungei growth tonic. Decne, obtained by soaking them in dark soybean extracts 0005. In the patent document 4 (JPH03-206019A), it was and alcohol. Further, the color and gloss of hair can be also described that dark soybean, Polygoni multiflori Radix improved by increasing the content of Longan seed. In addi etc. were used as external components for restoring lost hair. tion, in the agent for hair growth of the invention, the extracts And, in the patent document 5 (JP H06-227946 A), it was of the processed semi-mature soybean, the processed described that herbal medicine extracts, such as extracts of Polygoni Multiflori Radix, the processed Cynanchum bungei ginseng etc. which were extracted with alcohol Such as “Hua Decne and the Longan seed can be combined. ngjiu (yellow rice or millet wine; a type of Chinese alcohol) 0019. The agent for hair growth of the invention can be etc. were used for promoting hair growth. taken orally or can be added to foods or drinks. On the other 0006 Further, in regard to the Sapindaceous plant Longan hand, it also can be prepared as an external product. (Euphoria Longana (Lour.) Steud.), it is common knowledge that components extracted from the flesh of the Longan fruit EFFECT OF THE INVENTION with water and/or organic solvents had positive effects on hair 0020. In this invention the positive results of the agent for growth and restoring hair (patent documentó: JPH06-100421 hair growth is based on the use processed semi-mature Soy A). And, it was described that The Longan seed extracts have bean, processed Polygoni Multiflori Radix, processed Cyn a moisturizing effect and can be mixed into an external skin anchum bungei Decne, and Longan seed etc. as active ingre preventive (patent document 7:JP 2002-145732A). dients. Especially, this agent for hair growth has no side 0007. However, as mentioned above, the conventional hair effects when used externally or internally, it can notably tonics (in Japan are classified into the quasi-drug tonics (a improve hair growth within a short period of time; ranging term of Japanese Pharmaceutical Affairs Law)), which have from 6 to 12 weeks, can return hair to its normal hair colour components extracted from herbal medicines and foods. (for example from white to black) and can improve the gloss These tonics are easily obtainable, but the hair growth effect of hair. is insufficient. On the other hand, hair tonics, which are clas 0021 Moreover, existing hair tonics usually are offered as sified as drugs (a term of Japanese Pharmaceutical Affairs capsules or tablets types and therefore not convenient to take, Law) and are used as antihypertensive and male hormone because they resemble drugS/medication. The agent for hair inhibitor, have some hair growth effect, but their side effects growth of the invention has not only an excellent hair growth are severe. Further, in order to be able to purchase drug hair effect, but also can be regarded as a delicious food, for tonics it is necessary to see a doctor and obtain a prescription. example in form of a cookie, a rice cracker, an Okaki (a US 2009/01 04295 A1 Apr. 23, 2009

Japanese cake), an Arare (a Japanese cake), Japanese cakes color of the seed coat. Yellow soybeans are usually called and cracker etc. . . . . which might, in the opinion of the “soybean (Daizu), and are generally used as raw material for inventor enhance the use. In this sense, the agent for hair boiled soybean, natto, bean curd and miso etc. Blue Soybeans growth of the invention is an important chapter in the hair are used as raw material for soybean flour and Japanese-style tonic history. confectionery. Black soybeans are usually called “black soy bean (Kuromame)' and are used as food. BRIEF DESCRIPTION OF THE DRAWING 0031. Any kind of soybean can be used as raw material for 0022 FIG. 1 shows changes in the degree of allopecia and the processed semi-mature Soybean in this invention. The thin hair before and after taking the agents of hair growth of yellow soybean however is especially suitable for the pro this invention. There are significant results of hair growth in cessed semi-mature Soybean. Further, soybeans are Subdi the following groups; the compound ingredients 1 group, the vided into large-grained, kmiddle-grained and Small-grained compound ingredients 2 group and the compound ingredients Soybeans, according to the size of the seeds. Any sizes of 3 group. soybean can be used for this invention. Furthermore, any 0023 FIG. 2 shows a subject's hair condition before and Soybean Strain can be used for this invention, too. after taking the agent of hair growth (A: Before taking, B: 0032 For this invention soybeans with its seed coat or seed after taking). These data support the results shown in FIG.1. bud removed, or soybeans with its seed coat and seed bud The hair growth effect of the compound ingredients 1 was removed can be used as well as soybeans irradiated with confirmed in this figure. gamma rayS. 0024 FIG. 3 shows a subject's hair condition before and 0033. It was reported that sitosterols, lipids, peptides, after taking the agent of hair growth (C. Before taking, D: isoflavones, Saponins and polysaccharides extracted from after taking). These data support the results in FIG.1. The hair Soybeans or soybean ferment extract etc. have hair growth growth effect of the compound ingredients 2 was confirmed effect. However, raw soybean has a stimulating effect on the in this figure. stomach and according to JP 2004-182687 A, reactants of the 0025 FIG. 4 shows a subject's hair condition before and enzyme hydrolysis of Soybean proteins have a "hair growth after taking the agent of hair growth (E: Before taking, F: after inhibitor effect” instead of a hairgrowth effect. For this inven taking). These data support the results FIG.1. The hair growth tion, raw soybeans were processed to the processed semi effect of the compound ingredients 3 was confirmed in this mature Soybeans. These processed semi-mature Soybeans are figure. save, have high hair growth effects and thus can be used for 0026 FIG. 5 shows changes in the pain pattern at the hair the invention. root before and after taking the agent of hair growth in this 0034. In this invention, “the processed semi-mature soy invention. The sensation of pain was increased in the groups bean” refers to soybeans that were prepared with heat in order of the compound ingredients 1, the compound ingredients 2 to remove their typical taste found in their raw form without and the compound ingredients 3. pulverizing them by excessive heating. 0035. For the heating process any kind of heater can be use THE BEST MODE OF THE INVENTION for this invention, for example, gas stove, oven, microwave oven, toaster etc. In laboratories and factories hot plates, a 0027. What is hair growth? “Keeping the current hair mantle heater, an electric furnace, a mule heater, a Maki bill health, preventing hair loss and increasing the strength of type heater, a throw type heater, a lab heater, an electric stove hair, is the definition by the Japan Hair Science Association. The effects of hair growth in this invention basically support and etc. Moreover, any Small cooking tool can be used. this definition. To be more specific, it can improve hair thick 0036. The methods for making processed semi-mature ness, hair color and hair gloss. New hair grew on the scalp soybeans are not restricted to the following methods. More where hair had already been lost, in other words, it enhances over, heating conditions may vary due to the following fac hair-growth (in Japanese pronunciation is "Hatsumou”). The tors; modality of the heat instrument, volume of the soybeans meaning of the hair growth effects in this invention includes and whether the Soybean was soaked in water or not, etc. this "Hatsumou’ effect, the meaning has a wide sense. 0037 (1) Preheat a frying-pan on a gas stove, then put the 0028 Now, I want to explain the manufacturing methods Soybeans into the frying-pan, stir the Soybeans from thirty of each component within the invention Such as the processed seconds up to ten minutes (desirably one to five minutes) semi-mature soybean, the processed Polygoni Multiflori while keeping the temperature a the same, medium level. Radix, the processed Cynanchum bungei Decne and Longan 0038 (2) Put the soybeans in boiling water (90° C. to 100° seed and the composition ratio of the invention. I also want to C.) for three seconds up to sixty minutes (preferably ten explain how to use the invention as follows. seconds to ten minutes, more preferably thirty seconds to three minutes) to heat the beans. Instead of the hot water, any The Components in the Invention kind of food oil (for examples, salad oil, Sesame oil, frying oil, safflower oil, olive oil and processed element oil, and its kinds “The Processed Semi-Mature Soybean” are not restricted especially) can be used. The oil temperature 0029. The raw material of the processed semi-mature soy was between 60° C. to 480°C., preferably 100° C. to 300°C., bean in this invention is soybean (Binomial name; Glycine more preferably 180° C. to 250° C. Other than boiling water max (L.) Merr.), it belongs to Glycine, Fabaceae and the color and food oil all edible liquids can be used. of its seeds is yellow. This kind of soybean originates in 0039 (3) Soak soybeans in warm water (within the range China. It was brought to Japan during the Yayoi period and of 30° C. to 90°C., preferably 60° C. to 80°C.) forten minutes was permeated during the Kamakura period. to three days. 0030. In Japan, soybeans are mainly classified as yellow 0040 (4) Put the soybeans into a steamer etc. and heat the Soybeans, blue Soybeans, black Soybeans according to the beans by using steam of 100° C. to 380° C. (preferably 150° US 2009/01 04295 A1 Apr. 23, 2009

C. to 300° C.) for three seconds up to sixty minutes (prefer an alcohol that ripens for a fair amount of time (from 1 year to ably ten seconds to ten minutes, more preferably thirty sec several decades), and its raw material is chiefly glutinous rice onds to three minutes.) and wheat malt. It's name huang jiu-Chinese-yellow 0041 (5) Heat soybeans by using an oven at the range of wine is derived from its yellow colour, with a brown or 200° C. to 220° C. for 20 minutes, then at 170° C. for 30 amberglow. Since it is ripened for an extended period of time, minutes, and then at 150° C. for 40 minutes. it is also known as laojiumeaning "aged liquor in Chinese. It was introduced to Japan by Nakagawa Tadahide in the Edo “Processed Polygoni Multiflori Radix” period (Nakagawa Tadahide: “SinZokuKiMon”, year 1799 A. 0042. The processed Polygoni Multiflori Radix in the D. “Shao Xingjiu is one kind of Huangjiu well-known in agent for hair growth of this invention was obtained by Soak Japan. The alcohol content of Huangjiu is roughly 14-20%. ing black soybean extracts and liquors to raw Polygoni Mul Depending on the time it is given to ripen, there are a few tiflori Radix. Polygoni Multiflori Radix (Heshouwu) is the differences in the percentages. Huangjiu is commonly used dry root of Polygonum Multiflorum (binomial name: for cooking in China, its country of origin. Polygonum multiflorum Thunb.). It was recorded in the book "Kai Yuan Ben Cao” during the Song Dynasty in China. The 0048 For the purpose of deriving a sufficient hair growth dry root is referred to as "raw Polygoni Multiflori Radix', and stimulating effect of the Polygoni Multiflori Radix used in that treated with heat as “mature Polygoni Multiflori Radix'. this invention, Isoaked the Polygoni Multiflori Radix in black 0043 Polygoni Multiflori Radix includes components of Soybean extract and liquor (Huangjiu), to then use the result various kinds of dianthrones such as emodin, rhein, aloe ing product as the “processed Polygoni Multiflori Radix'. In emodin, chrysophanol, physcion, etc. as well as components this case, the above-mentioned “Black soybean extracts are of 2, 3, 5, 4-tetrahydroxy stilbene-2-O-beta-D-glucoside, hot-water extracts which are obtained by boiling black soy 3-methyl-1, 6, 8-tri-hydroxyanthraquinone, 2,6-dihydroxy beans. benzoic acid, 1,2-propanediol-1-(4-hydroxy-phenyl), emo 0049. For this invention, the processed Polygoni Multi din-8-O-beta-D-glucoside, 8-O-beta-D-glucopyranoside, flori Radix was obtained by drying the compound ingredients chrysophanol 8-O-beta-D-glucopyranoside, torachrysone which were then soaked together with the black soybean 8-O-beta-D-glucopyranoside, aloe-emodin 8-O-beta-D-glu extract and the liquor. It is desirable that these processes were copyranoside, chrysophanol 8-O-beta-D-(6'-O-malonyl)glu condensed with a cooker whilst heating. There are other pro copyranoside, (+)-lyoniresinol-3-alpha-O-beta-D-glucopy cessing methods one can use for obtaining processed ranoside, 2.3.4",5-tetrahydroxy-trans-Stilbene-2-O-beta-D- glucopyranosid, 2,3,4, 5-tetrahydroxy-trans-Stilbene-2,3-di Polygoni Multiflori Radix, therefore, one is not restricted to O-beta-D-glucop yranoside.Me indole-3-(L-alpha-amino the method mentioned above. alpha-hydroxypropionate), citreorosein, Me gallate, “Processed Cynanchum bungei Decne' anthraquinones, Sennoside A, Sennoside B, etc. 0050 For this invention, the processed Cynanchum bungei 0044) Further characteristics of Polygoni Multiflori Radix Decne was used as the raw material to obtain the processed include containing a large amount of Ca, Fe, Cu, K, Mn, Zn, Cynanchum bungei Decne, which is the name of an herbal and P for the average content of the plant. medicine (brand name). Usually, Cynanchum bungei Decne. 0045 Polygoni Multiflori Radix contains a kind of (binomial name) is readily available in herbal medicine mar Antorakinon component. Therefore, if taking Polygoni Mul kets. However, Cynanchum auriculatum Royle (Asclepia tiflori Radix in its raw form, an individual will either develop daceae), Asclepias hastata Bunge. Enum. Cynanchum loose stool, light diarrhoea or diarrhoea. For this reason hastatum Lamarck, Symphyoglossum hastatum (Bunge) Polygoni Multiflori Radix is usually taken in its mature form. Turczaminow, Vincetoxicum hastatum (Bunge) Kuntze are all Mature Polygoni Multiflori Radix has the effects of nourish marketed as raw Cynanchum bungei Decne though is a small ing and strengthening and is used to treat tinnitus, gray hair, amount, too. In other words, the compounds contained within sleeplessness, defective sperm growth, decline of the lower Cynanchum bungei Decne occur in several kinds of plants. body, hyperlipemia, chronic hepatitis, neurasthenia, etc. This is to be admitted in China. Recently, based on its effect of decreasing serum cholesterol, it has been added to various hair tonics to control the sebum 0051. The chief area of production of Cynanchum bungei secretion of the skin on the scalp (for example, JPH02-48514 Decne is Shandong province, China. Its natural growth in A, etc.). However, when used on its own mature Polygoni Japan has not been confirmed. Multiflori Radix is insufficient in stimulating hairgrowth, and 0.052 The compounds contained within Cynanchum so is often used in combination with other medicinals. bungei Decne include Bungeiside A, Bungeiside B, Bungei 0046. On the other hand, black soybean belongs to Gly side C. Bungeiside D, Blumenol, (-)Leucanthemitol, beta cine, Fabaceae as previously stated, and the colour of the Sitosterol glucoside, 4-Hydroxyacetophenone, Cynanchol, coating of its seed is black. Within Japan, Hokkaido and etc. Okayama Hyogo Prefecture are its chief districts of produc 0053 All the parts of Cynanchum bungei Decne. have tion. It is thought to be effective in the treatment of thrombo pharmacologic effects. Usually, the parts used include the sis, hypertension, liver complaints, diabetes, common Stone root, stalk, and wisteria. The dried parts are referred to “raw diseases, arthritis, weight loss, and cancer prevention. Black Cynanchum bungei Decne'. It is used as an antias thenic drug Soybean is prepared in a variety of ways, including as a tea, due to its effect of improving the function of the liver, kidneys milk, bean cake, cake, Okaki, miso, and stew. and blood. 0047 Moreover, liquors that are in general use such as 0054 For this invention, the processed Cynanchum bungei those used for drinking or cooking can be used to process the Decne was obtained by using the same method that was processed Polygoni Multiflori Radix. The liquor “Huangjiu employed in the processing of the Polygoni Multiflori Radix, is especially Suitable in stimulating hair growth. Huangjiu is i.e. soaking the raw Cynanchum bungei Decne in black Soy US 2009/01 04295 A1 Apr. 23, 2009 bean extract and liquor (Huangjiu) and heating, then drying it 0063. When preparing extracts of each active ingredient to obtain the processed Cynanchum bungei Decne. contained within the agent for hair growth, it is desirable that processing is done after either cutting, drying, or crushing “Longan Seed' each of the raw materials to enhance extraction efficiency, it is 0055 For this invention, “Longan seed' is the seed of the possible to extract the active ingredients by using a Supercriti Longan plant (Binomial name: Euphoria Longana (Lour.) cal fluid and a Sub-critical fluid, or by soaking in a solvent. To Steud.). It is the fruit of an evergreen tree and belongs to the increase the extraction efficiency when using the extraction Sapindaceae family, growing from South Asia to Southeast solvent, it is better to stir the solvents or to homogenize the Asia and China. In China, the flower of Longan usually extraction in the solvents. Regarding the temperature for blooms from March until April, and its fruits are ripe from extraction, it is desirable that it be within a range of around 5° July until October. Longan contains components such as Uri C. to 10 degrees lower than the boiling point of the solvent dine, 5-(Hydroxymethyl)-2-furfuraldehyde, 1,1-dimethyl-2- used. As far as the extraction time is concerned, although it propenyl 1-O-B-D-glucopyranoside, Et beta-D-glucopyrano differs depending on the kind of solvents along with the side, 5-(hydroxymethyl)-2-furfuraldehyde, alpha- and beta temperature used for extraction, it is desirable to be from amyrin, lupeol, 24-methylenelanost-8-en-3beta-ol. about 1 minute to roughly 14 days. 24-methyleneparkeol, 24-methylenecycloartanol. 4 4-me 0064 One is not especially restricted in regard to the kind thy Longan SeedteroLongan seed, 6 4-desmethyllongan seed of extraction solvents used. Water and the org-solvents are terolongan seed, etc. enumerated, for instance, the following materials may be 0056 Longan fruit is composed of the husk (testapart), the used as an org-Solvent: alcohols and butanols such as metha flesh (provisory testa) and the nucleus (seed). Among these nol, ethanol. 1-propanol, 2-propanol, n-butanol, S-butanol, parts, the meat of has a peculiar Sweetness with thin Smelland t-butanol, ethyleneglycol, 1,3-butyleneglycol, propylenegly is consumed as a food. In China, the dried meat is known as col, dipropyleneglycol and glycerin etc., ethers such as "Longan meat' and is recognized as having a “blood tonify diethyl ether and dipropyl ether; esters such as butyl acetate ing effect. In other words, it improves the circulation of the and ethyl acetate etc., ketones Such as acetone and ethyl blood as well as its function and therefore has been used since methyl ketone etc.; organic acids such as formic acid and antiquity within the herbal medicine pharmacopeia. More acetic acid etc., dimethylsulfoxide, acetonitrile, tetrahydrof over, in Japan the blood-tonifying effect of Longan meat is ran, dioxane, and phenols, and other parents oily org-solvents recognized, contributing to the Japanese Pharmacopeia as a (such as chloroform, pentane, hexane, cyclohexane, benzene, traditional herbal medicinal, and is used as an insurance drug. toluene, xylene and vegetable lipids such as colza oil). It is 0057. Until today, Longan seed is considered worthless as possible to use these solvents by selecting one or several a food or medicinal substance and therefore its value aban among these. From a safety stand point, water or ethanol is doned. desirable. Moreover, physiologicalsaline, phosphoric acid 0058 As far as the application of the hair growthtonic is buffer and phosphate buffer saline etc. may be used. In addi concerned, Longan seed can be used for either damp or dry tion, one may also selecta Supercritical fluid and a Sub-critical conditions. It is thought that the hair growth effect is further fluid Such as water, carbon dioxide, ethylene, propylene, etha increased when Longan seed is processed in a similar way to nol, methanol, and ammonia, etc. the Polygoni Multiflori Radix. “Other Ingredients' “Extract of Each Ingredient' 0065 Aside from the active ingredients mentioned above, 0059 Extracts obtained from processed semi-mature soy the agent for hair growth in this invention can also be used by bean, Polygoni Multiflori Radix, Cynanchum bungei Decne combining foods and beverages, raw food Substances or and Longan seed with solvents, as well as dried powders of medicines, etc. For example, mixing raw materials that these extracts, can be used for the agent for hair growth. The improve health, natural medicinal materials (such as curative extracts obtained from a prepared mixture comprising the plants, or curative animal products or minerals), traditional powders of the processed semi-mature Soybean, Polygoni Japanese drugs, traditional Chinese drugs, Western medi Multiflori Radix, Longan seed and Cynanchum bungei Decne cines or other compounds with the extract material. Some can be used. In addition, it is possible to use a combination of examples are enumerated below. non-extract and extract Substances. 0.066 Tacasabrou is enumerated as one of the natural 0060. The above extracts can be used for the agent for hair medicinal materials. Tacasabrou (Eclipta prostrata L.) growth after one of the following procedures have been com belongs to the Asteraceae family. Its Japanese name is Tacasa pleted: concentrating the above extracts, dissolving the dry brou, is known as Hanliancao, Mohanlian, Lichang or extracts into water or a polarized solvent, or refining (Such as Lichangcao in Chinese and is referred to Eclipta in English. It through bleaching, deodorization, desalination, etc.), or frag has the effect of blackening hair (which is enhanced when menting those extracts that are within the range in which their used together with ginger). Tacasabrou is an annual herb functionality is not compromised, with the use of a chromato widely distributed from the temperate Zones to the tropics. In graph. Japan, it grows in Honshu and the Southern regions, however 0061 The above mentioned unprocessed as well as pro not in Hokkaido. It grows in rice fields, in proximity to levees, cessed (fragmented) extracts may be frozen or dried after and waterway walls, etc. and is also referred to as a rice field being processed (or fragmented). The resulting matter can be weed. It has white flowers that blossom from Summer to dissolved into a solvent or can be wrapped to beshicl and the autumn and seems to have become a naturalized plant origi micro capsule etc. Such as riposorm prior to use. nally brought from China with the introduction of rice farm 0062 Next, I would like to explain the methods of pro ing. After World War II, America introduced Tacasabrou to cessing for the above mentioned extracts. Japan and became a naturalized plant. US 2009/01 04295 A1 Apr. 23, 2009

0067 For this invention, the Tacasabrou from any region cuanke, cuangu, cuanxi, Xicaogen, cantui, Sennna, cuanbei, may be used. Tacasabrou has an antibacterial, anti-viral and Xuanfuhua, Sennburi, Xianmao, Chuanglianzi, caoguo, Zha anti-inflammatory effect and has been used as a curative plant ojiaochi, Zhaojiaozi, Zhaojia, ZhuyaZhaojia, shangshenzi, in China for 1000 years or more. From a traditional Chinese Shangdeshi, cangerzi, cangshu, gulicangshu, caodou, Samg medicine perspective, Tacasabrou is used to tonify the Kid baipi, Sangqiao, Sangye, Sangdeye, chebuye, Shumu, shuye, neys (referred to in Japanese as “Holin') as well as treat dahuixiang, dahuang, jinwendahuang, dahaizi, dagencao, various hemorrhagic conditions. dagendezhongzi, luopuzi, daizheshi, daqingye, Dazhao, naZ 0068. As other natural plants or animals or minerals ime, dafupi., gaoyuancao, Zhexie, Zhelan, Ta-merikku, yujin, though it is not restricted especially, for instance, the follow kuragenpu, danshen, danZhuye, Zhuye, tannpopodegen, ing can be enumerated; pugongyinggen, Zhuru, Zhuru, Zhujierenshen, Zhuye, Zhimu, Mutongzi, Akebi's Manxingjing, Mutong Ashitaba, Asunaro chaye, diyu, dixiang, dizi, diaotenggou, Zhuling, chenpi, tsu leaf Gancha, Ganchaduru, Amadokoro, Yamaren, Araragi, chiakebi, tutongchao, luchao, Tsurudokudami's root, Tsu Awabirui's gara, Shijueming, Ikarikusai, Yuliren, IZui, Yiwei, runa, bingqianshe, Tinglizhi, Tioanzhuhuang, tianzhuhuang, Itijiku’s mi, Itiku’s leaf. Ityou, Dao miao, Weillngxian, Yan tiannanxing, tianma, tianmushi, tianmuman, Tianmu, tian qianshe, Yanlu, Yinchenhao, Mianyinchen, Yinyanghuo, mendong, Donggua, danggui, dahedanggui, dongkuizi, tina Uikyou, Ukonn, wutou, Wuji, Wuzheigu, Wumei, Wuyao, ghuma, dengxin, dengXinchao, dangshen, daodou, Utubogusa's huashui, Tuyuliang, Guobaijian, Uwaurusi, dongchongxiachao, tangduhuo, tao ren, chenpi, dangyao, eijitu, eZoukogi, yanhuSuo, yan ming cao, huangqi, Ougonn, Senburi, tuguagen, tuguagen, tuguashi, duhuo, tangduhuo, jianhuang, huangjing, huangtu, huangbo, yingpi, Wangbuli yuxingchao, Dokudami, Jyuyaku, tusizi, Tochi fruits, uXing, huanglian, ootudirahuji, fangji, oobako's Zhongzi, duZhong, tutongchao, tufulin, Shanguilai, tubieia, bieia, cheqianzi, Oobako's quancao, cheqiancao didiecao, yuanzhi, Liaobuzhi (Toritomarazu), mumu, Tonburi, Difuzhi, NaZuna, Xiagucao, kaika, haijinsha, huailiuqi, gositu, liuqi, jiezi, hai Natamame, baidaodou, roudou, roudoukou, Natsumeru, Songzi, haitongpi, hairencao, makuri, jiubai, aiye, yomogi, Narukoyuri roots, huangjing, nantianshi, nantianye, nanman kaoosi, kaki's leaf, kaki's heta, Xiagucao, kezi. Gajyutu, mao, Nigaki, Rouchongrong, roudou, jinmu, ruXiang, Niwa Kakkou, Gegen, huashi, kanokonnu, kamiture, kayaturikusa, toko, Niwatoko leaf, Ninjin, Gosyuninjin, shengganrenshen, kayanomi, garana, Kariraku, kezi, hualinomi, mugua, lougen, shensairenshen, baishen, qushen, maorenshen, rendong, karokonn, kalousji, kalouren, chuanliu, kawaratake, jixing NeZu fruits, duSongzi, Nezumimochi, nVZhenzi, beinu, chua Zhu, kawarayomogi, yinchehao, ganjiang, guanzong, guan nbeimu, chuanbei, maiya, baijiezi, boZiren, baidou, baix Zhong, gancao, dongbeigancao, Xibeigancao, kannZou, Zhi ianpi, baitouweng, baitaohua, baidaodou, bainantian, nan gancao, guanzhong, kuandonghua, kuandonggen, tianshi, baibiandoui, biandou, manmendong, Hanliancao, kikyou, jigen, juhua, hangjuhua, Zhizi, Zhishi, kaibianmaimendong, bagetian, pohuzhi, Hakobe, biajiaoshi, Zhike, kisasage, jixing, jixingZhu, beishashen, jicaogen, jipi. LianZhi, bajiao, dahuixiang, bohe, Juemingzhi, Paozhi-Juem kihada, huangbo, guiban, gimunemasirubeSuta, huguama, ingzhi, Hanamotsu, Habu-kusa, Houji-Habucya, bindianshe, qianghuo, Xingren, yuzhu, kirannkusa, jinyingZijingan, jiny binfangfeng, panguo, banxia, Banzakuro leaf banzhilian, inhua, yinchaihu, jinzhencai, jinqiancao, Mizuhik, Xianhe panshiliuye, pangdahai, dahaizi, bannagen, Hikai, bianhua, cao, fruit of Guaba, Panguo, Guaba, Goujizi, kukonomi. bianhuadege, Hikiokosi, yanmingchao, maorenshen, mao Kukonogenpi, digupi, goujiye, kushen, kuZunonemodo, renshen, lindeshi, ganye, mazi, tanghuma, baihe, baizhi, gegen, gouji, kutinasi, Juma, Kumassa, Xiongliu, kurumi, baishu, baitan, baiwen, baibugen, baihuasheshechao, kuchenpi, heiwenzi, Sangca, Sangye, Sangdeshi, keigai, Baijiangchan, baijiangchan, hiru, Shuizhi, pipaye, bing jingjie, jixueteng, guizhi, guipi, guitongguipi, guangnan langzi, fupenzi, fuling, fuzi, paofuzi, Bieia, tubieia, Hongy guipi, dongXingguipi, yueguishiye, ketumeixi, maorenshen, inghua, bianxu, fangyt, maogen, mangchong, fangfei, qianniuzi, kennjitu, quanshen, Xuanshen, gennnosyouko, puhuang, Bokusou, pugongyinggen, bugu Zhi, pohuzhi, miaoyi, maiyatanghuayi, honghua, hehuanpi, hangjuhua, mudanpi, muli, kuihua, mahuang, quiemahuang, mahua jiangxiang, kousi, XiangXu, hongshen, Xiangfuzi, genmi, nggen, Makuri, hairenchao, maziren, Matatabi, tianmuman, houpi, houpishi, haoben, niuhuang, Wujiashen, niuXi, huaini Matatabi fruits, tianmushi, chongliu, Songdeshi, haisongzi, uxi, cuanxi, Wuzhuyu, gushuibu, hutaorou, Wubeizi, hupo, Songye, Songteng, Matsuyani, Songzhi, manjinzi, mimeng niupangzi, huma, Wuweizi, huyuba, caihu, caihumu, Xixin, hua, Mitsurou, Sarasimituryou, Mirobaran, kezi, Wuhuaguo, Zakuroguopi, Shiliuguopi, Sahurann, shuoyang, Shanguilai. Wuhuanguo, Wuhuaguoye, Wuhuanguo leaf, mumu, shanzhazi, Shanzharou, Shancigu, Shanjizi, chansha, Shan Mugunoki, mianyinchen, muzhe, mutong, mutianmiao, Zhuyu, Shanjiao, Shandougen, Shaunzhaoren, shanbiandou, Matataminoryu, mugua, muXiang, toadeye, menjin, shegan, Shanyao, Sanlin, dihuang, shudihuang, Ziyan, Zihuadiding, yizhi, yizhiren, yimuchao, yeliaoteng, shicheshi, Yatsumeran, Sigualou, chiwujia, digupi, Zigen, yingZigen, ruanzigen, Xiaongdan, Yukinosita, Yuzuri leaf, Baihe root, baihe. chishi, Zishiyan, Zishuzi, lizi, Jilizhi, siturisi. Difuzhi, Jiugan Yuyiren, Aiye, aiye, leiwan, laizhi, luopuzi, luohanguo, cao, chishizhi, Shaoyao, daheshaoyao, daoxieshaoyao, luopuzi, ligenpi, longyanrou, liujinu, longgu, Magnesium chishao, shechuangzi, shashen, beishashen, cheqianzi, che Sulfate, longdan, liangjiang, gaoliangjiang, lvdou, lingzhi, qiancao, Syamusi, chongweizi, Xiu Zhifuzi, shudihuang, liandiao, lianqianchao, Kakitoosi, lianrou, LianZhi, lurong, Shusha, Zonglushi, Shengjiao, Syouga, Songzi, Xiaomai, lufengfang, lulutong, heqianghuo, honghua, liulonghuang, cangpu, cang.pugen, shengma, jiaomu, Xiaoliangiao, lurongdabiwan, Zhiyungao, Herbal medicine plaster of Utida, diqiecao, nuZenzi, dilong, dilonggan, Xinyi, Jinqi. Shenju. Bath preparation of Utida, yunnanhuangjin, yunnanpi liushenju, qinjiu, SuikaZuradejingye, rendong, SuikaZurano anyujin, yunnantianqi, tianqirenshen, lingzhi, lingZhifeng, hana, jinyinhua, shuizhi, Sugina, dougu, Xianggu, Seisousi, New Caihor ionizing calcium of Kichitosan and Tida of qingdai, qingpi, Xiyangrenshen, chishao, Shicanggen, agaricus processed food and Utida, ASreb, fengmi, and adlay shisongzi, Shiliuguopi, Shijieming, Shigao, Shidou, jiegupu, processed food, Pual tea, Caki No leaf, Nacacha, and Meg Zeratinn, Xianhecao, quanxie, cuanxiong, cuanyujin, qianhu. Srinoki tea, etc. US 2009/01 04295 A1 Apr. 23, 2009

Moreover, the following herbal medicines can be enumer Ribes tenue Jancz. Var. viridi. Florum Cheng, Scopolia acu ated, too. Prunella vulgaris L., Prunella hispida Benth. tangula C. Y. Wu et C. Chen, Saururus chinensis (Lour.) Ophioglossum pedunculosum DesV., Ophioglossum thermale Baill. Viola tricolor L., Oxalis griffithii Edgew. Et Hook.f., Kom. Ophioglossum reticulatun L. O. petiolatum Hook. Parthenocissus heterophylla (Bl.) Merr., Chlorophytum Cirrhopetalum henryi Rolfe, Stephania graciliflora Yama laxum R. Br. Pachysandra Stylosa Dunn, Cinnamomum moto, Securinega suffruticosa (Pall.) Rehad., Lepisorus con tamala (Ham.) Nees et Eberm. Lysimachia insignis Hemsl., tortus (Christ) Ching, Senecio dianthus Franch. Erigeron Anaphalis bicolor (Franch.) Diels, Neocinnamomum dela annuus (L.) Pers. Tetrastigma delavayi Gagn. Veronica spu vayi H. Liou, Cimicifiiga acerina (Sieb. Et Zucc.) Tanaka. ria L., Achillea alpina L. Achillea wilsoniana (Heim.) Heim. Lindera obtusiloba B1. Vicia unijuga A. Br., Trifolium repens Indigofera pseudotinctoria Matsun., Indigofera parkesii L., Cyperus iria L., Berberis Sargentiana Schneid. Berberis Craib, Anotisingrata (wall.) Hook. f. Begonia wilsonii brachypoda Maxim. Berberis dictyophylla Franch. Var. Gagn. Ligularia melumbifolia (Bur. et Franch.) Hand.-MaZZ. epruinosa Schneid., Berberis diaphana Maxim. Tilophora Parochetus communis Ham... Kyllinga monocephala Rotth. ovata (Lindl.) Hook. etSteud., Tilophora crebriflora, Evodia Pittosporum glabratun Lindl., Solidago virga-aurea L. var. tepta (Spr.) Merr., Evodia lepta (Spr.) Merr., Saururus chin leiocarpa (Benth.) A. Gray, Indigofera pseudotinctoria Mat ensis (Lour.) Baill. Clerodendron serratum (L.) Spr., Clero sum. Maianthemum bifolium F. W. Schm., Schisandra dendron serratum (L.) Spr. Var. amplexifolium Moldenke, bicolor Cheng, Limonium bicolor (Bge.) O. Ktze. Piper boe Potentilla freyniana Bornm. Potentilla freyniana Bornm. Var. himeriaefolium wall. var. tomkinense C. D.C., Rosa multiflora sinica Migo, Scleria elata Thw. Potentilla freyniana Bornm. (Thunb.) var. platyphylla Thory, Mahonia bealer (Fort.) Enteromorpha clathratai (Roth) Grev. Enteromorpha prolif Carr., Mahonia fortunei (Lindl.) Fedde Mahonia japonica era (Mull) J. Ag., E. cinoressa (L.) Grev., E. intestinalis (L.) (Thunb.) DC., Syzygium Cromaticum (L.) Merr. Et perry, Link. Zingiber officinale Rose. Rhus verniciflua. Stokes, Erycibe obtusifolia Benth., Syzygium aromaticum (L.) Merr. Brassica chinensis L., Rehmannia glutinosa (Gaertn.) et Perry, Zornia diphylla Pers. Cornus macrophylla wall. Libosch. Rehmannia glutinosa Libosch., F. hueichingensis Syzygium aromaticum (L.) Merr. Et Perry, Zornia diphylla (Chao et Schih) Hsiao, Corydalis tomentella Franch. Ipo Pers. Gynostemma pentaphyllum (Thunb.) Mak. Schefflera moea hungaiensis Lingelsh. Et Borza. Odontobutis obscura arboricolai Hayata, Schefflera venulosa (wighti et Arm.) (T. et S.), Discolia vittifrons Sch. Evolvulus alsinoides L., Harms, Buddleia lindleyana Fort. Macropanax rosthornii Illicium henryi Diels, Illicium yunnanensis Franch. Talinum (Harms) C. Y. wu ex Hoo, Mosla cavaleriei Levl. Actin paniculatum (Jacq.) Gaertn., Senecio Chrysanthemoides Odaphne Obovata Bl. A locasia cucullata (Lour.) Schott. DC., Rumex madaio Mak. Sinula helenium L., Equisetum Akebia quinata (Thunb.) Decne. Akebia trifoliate (Thunb.) debile Roxb., Roscoea intermedia Gagn. Bolbostemma pan Koidz., Akebia trifoliate (Thunb.) Koidz. var. australis (Di iculatum (Maxim.) Franquet, Achyranthes bidentata B1. els) Rehd. Holboelia latifolia wall. H. angustifolia wall. Acyranthes longifolia Mak. Achyranthes aspera L., Stan Lampetra japonica (Martens), Hydrangea macrophylla lianthus thorelii gagn. Platanthera chlorantha Cust. EX (Thunb.) Ser. Galium aparine L. Galium asperifolium wall. Rehb., Melothria indica Lour., Melothria heterophylla Cacalia ainsliaeflora (Franch.) Hand.-MaZZ., Dysosma ple (Lour.) Cogn. Arisaema intermedium Bl. Asparagus filici iantha (Hance) woods. Dysosma veitchii (Hemsl. et wils.) nus Ham. ex D. Don, Asparagus meioclados Levl. Aralia Fu, Alangium chinense (Lour.) Harms, Alangium platanifo cordata Thunb., Angelica gigas Nakai, Lysimachia insignis lium, Harms Alangium lamarckii, Illicium verum Hook. f. Hemsl., Hypericum bellum L., Hymenodictyon excelsum Illicium lanceolatum A. C. Smith, Panax ginseng C. A. Mey. (Roxb.) wall. Unio sp., Hedychium coronarium Koen. Hedy Herminium monorchis (L.) R.Br. Panax ginseny C. A. Mey. chium spicatum Ham. Clerodendron trichotomum Thunb. Dracontomelon dao (Blanco) Merr. et. Rol, Dracontomelon Odontobutis obscura (T. et S.), Pseudolarix kaempferi Gord., dao (Blanco) Merr. et. Rolf, Zanthoxylum nitidum (Roxb.) D Chenopodium ambrosioides L., Smilax glabra Roxb., Smilax C., Helminthostachys zeylanica (L.) Hook. Euphorbia lanceaefolia Foxb. var. opaca A. D. C. S. mairel Levl., S. hylonoma Hand.-MaZZ., Cayratia corniculata (Benth.) menispermoiden DC., Alpinia japonica Miq., Cephalotaxus Gagn. Sarcandra glabra (Thunb.) Nakai, Bauhinia cham sinesis (Rehd. et wils.), Cephalotaxus harringtonia (Forkes) pioni (Benth.) Benth. Thesium longifolium Turcz. Thesium K. Koch var. harringtonia C. V. Fastigiata, Origanum vulgare himalensei Royke, Silene tenuis willd. Silene tenuis willd. L., Canpanumoea javanica Bl., Berberis julianae Schneid. var. rubescens Franch. Murraya paniculata (L.) Jack. Berberis gagnepaini Schneid, Hudrangea strigosa Rehd., Polygonum rude Meissn., Aspongopus chinensis Dallas, Hydrangea umbellate Rehd., Hydrangea paniculata Sieb., Asplenium varians wall. Anemone altaica Fisch. Cyperus Discolia vittifrons Sch. Apios fortunei Maxim. Wikstroemia alternifolius L. subsp. flabelliformis (Rottb. Kukenth.), Bau dolichantha Diels, Collocalia inopina Thayer et Bangs. hinia championi (Benth.) Benth. Murraya paniculata (L.) Achilea wilsoniana (Heim.) Heim. Talinum paniculatum Jack. Calanthe discolor Lindl., Calanthe tricarinata Lindl., (Jacq.) Gaertn., Rumex madaio Mak. Vaccinium fragile Euphorbia hylonoma Hand.-MaZZ. Peristrophe japonica Franch. Euphorbia prolifera buch.-Ham. Hymenodictyon (Thunb.) Brem. Canavalia gladiata (Jacq.) DC., Ainsliaea excelsum (Roxb.) wall. Lonicera confusa D.C., Vaccinium triflora (Buch.-Ham.), Canavalia gladiata (Jacq.) DC., wik fragile Franch. Gouania leptostachya DC., Hordeum vul stroemia indica (L.) C. A. Mey. Panax pseudo-ginseng wall. gare L. Ziziphus jujuba Mill. Var. inermis (Bge.) Rehd., var. notoginseny (Burkill) Hoo&Tseng, Panax pseudo-gin Rheum palmatum L., Rheum tanguticum Maxim. ex Reg., seng wall. Var. elegantior (Burkill) Hoo&Tseng, Panax Rheum officuinale Baill. Euphorbia pekinensis Rupr., pseudo-ginseng wall. Var. Wangianus (Sun) Hoo&Tseng, Knoxia valerianoides Thorel, Euphorbia Soongarica Boiss., Panax pseudo-ginseng wall. Var. bipinnatifidus (Seem.) Li, Euphorbia pekinensis Rupr. Var. japonensis Mak. Euphorbia Sparganium stoloniferum Buch.-Ham, Sparganium simplex pontica Prokh, Allium sativum L. Allium scorodoprasum L., Huds. Sparganium stoloniferum Maxim. Gynura Segetum Cirsium japonicum D C., Alisma canaliculatum A. Br. et (Lour.) Merr., Campylotropis cavaleriei (Levl.) C. Y. wu, Bouche, Leibnitzia anandria (L.) Nakai, Bauhinia faberi US 2009/01 04295 A1 Apr. 23, 2009

Oliv., Rubus multibracteatus Levl. & Vant. Hydnocarpus nopodium megalanthum (Diels) C. Y. Wu et Hsuan, Ampelop anthelmintica Pier. Colysis henryi (Bak.) Ching. Marsdenia sis bodinieri (Levl. et Vant.) Rehd., Lepidogrammitis rostrata griffithii Hook.f., Adenosma indanum (Lour.) Merr., Gryllus (Bedd.) Ching, Lilium concolor Salisb., Gallus gallus testaceus walker... wisteria venusta Rehd. et wils. Sargento jabouillei Delacour et Kinnear, Dioscorea opposita Thunb. doxa cuneata (Oliv.) Rehd. et wils. Myrsine africana L., Dioscorea japonica Thunb., D. deltoidea wall. Kaempferia Hordeum vulgare L., Schisandra micrantha A. C. Smith, galanga L., Allium japonicum Reg., Alpinia japonica Miq., Alpinia galanga (L.) Swartz, Heliotropium indicum L., Crataegus pinnatifida Bge., Crataegus cuneata Sieb. et Adhatoda vasica Nees, Clerodendron Cyrtophyllum Turcz. Zucc., Crataegus pinnatifida Bge., C. hupensis Sarg., C. San Polygonum tinctorium Ait., Isatis tinctoria L., I. indigotica guinea Pall. C. scabrifolia (Franch.) Rehd., Crataegus Oxya Fort. Baphicacanthus cusia (Nees) Bremek., Hygrophila cantha, C. curvisepalaz, C. monogyna, Allium nipponicum salicifolia (Vahl) Nees, Clerodendron cyrtophyllum Turcz. Fr. et Sav., Piper hancei Maxim. Melodinus suaveolens Neolepisorus ovatus (Bedd.) Ching, Schefflera delavayi champ. ex Benth., Geastrum hygrometricum Pers. Psychot (Franch.) Harms. Ulmus tonkinensis Gagn. Alpinia speciosa ria rubra (Lour.) Poir. Papaver nudicaule L. Subsp. Amu K. Schum. Girardinia palmate (Forsk.) Gaud. Mussaenda rense N. A. Busch, Rheum franzenbachii Mint., Glycosmis erosa Champ., Euphorbia nematocypha Hand.-MaZZ., Pistia citrifolia (wild.) Lindl., Desmodium racemosum (Thunb.) D stratiotes L., Rheum palmatum L. R. tanguticum Maxim. ex C., Clematis finetiana Levl. et Vant., Lilium concolor Salisb. Reg., R. officinale Baill. Heteropanax fragrams (Roxb.) Mussaenda pubescens Ait. f. Mussaenda parviflora Miq., Seem. Dolichos falcatus Klein, Pouzolzia sanguinea (Bi.) Aster ageratoides Turcz., Indigofera Szechuenensis Craib., Merr., Parthenocissus laetevirens Rehd., Vicia sativa L., Helicteres angustifolia L., Asparagus lycopodineus wall. ex Inula pterocaula Franch. Blumea densiflora (Heyne) DC., Beker, Cinnamomum obtusifolium (Roxb.) Nees, Garcinia Areca catechu L., Musa paradisiacal L. var. sapientum o. multiflora Champ. Naenorhedus goral Hardwicke, Salix tet Ktze. Indigofera tinctoria L., Lycoris aurea Herb., Didissan radenia Hand.-MaZZ., Sophora subprostrata Chun et T. dra sesquifolia C. B. Clarke, Lippia modiflora Rich. var. Sar Chen, Menispermum daurteum D C., Indigofera fortunei mentosa Schou. Stylophorum lasiocarpum (Oliv.) Fedde, Craib, I. amblyantha Craib, I. ichangensis Craib, I. carlesii Ampelocissus artemisiaefolia Planch. Dobinea delavayi Craib, I. potaninii Craib, I. Kirilowii Maxim. et Palib., Dun (Baill.) Engl., Euphorbia hirta L., Pterospermum grande baria circinalis (Benth.) Bak. Beesia calthaefolia (Maxim.) Craib, Rubus setchuenensis Bur. et Franch. Anemone tomen Ulbr., Osyris wightiana wall. ex wight, Pyrus pashia Buch tosa (Maxim.) Pei, Caesalpinia magnifoliolata Metcalf. Ham. ex D. Don, Argyreia seguinii (Levl.) Vaniot, Michelia Pteris nervosa Thunb., Zanthoxylum dissitum Hemsl., vunnanensis Franch. Codonopsis convolvulacea Kurz. var. Uncaria macrophylla wall. Mosla dianthera (Ham.) Maxim, typical Anthony, Capricornis Sumatraensis Bechstein, Eucalyptus robusta Sm., Callicarpa macrophylla Vahl. Pittosporum glabratum Lindl., Ilex franchetiana Loes., Juni Machilus leptophylla Hand.-MaZZ. Senecio Orgzetorum perus taiwaniana Hayata, Rosa sericea Lindl., Ixeris chinen Diels, Senecio vulgaris L., Hypericum przewalski Maxim. sis (Thunb.) Nakai, Lactuca elata Hemsl., Symplocos cau Cayratia Oligocarpa (Levl. et Vant.) Gagn. Cruculigo date wall. Symplocos racemosa Roxb., Celastrus Stylosus capitulata (Lour.) O. Ktze. Lysimachia phullocephala wall. ssp. glaber D. Hou, Trema dielsiana Hand.-MaZZ. Hand.-Mazz., Cirsium eriophoroideum (Hook. f.) Petrak. Trema angustifolia Bl. Hieracium krameri Fr. et Sav., Lin Solanum spirale Roxb., Chrysosplenium hydrocotylifolium dera glauca (Sieb. et Zucc.) Bl. Carlesia sinensis Dunn, Levl. et Van. Polygala chinensis L., Polytrichum commune Cornus officinalis Sieb. et Zucc., Camelia japonica L., Hedw. Melastoma normale D. Don, Lysimachia Christinae Dioscorea opposita Thunb., Allium bulleyanum Diels, Isodon Hance, Lonicera similes Hemsl. Var. delavayi (Franch.) pubescens (Hemsl.) C. Y. Wu et Hsuan, Alpinia japonica Rehd., Setaria faberii Herrm. Sanicula lamellijera Hance, Miq., Cassia minosoides L., Polygala wattersii Hance, Mal Sanicula Staptiana wolff, Hosta Sieboldiana Engl. Bauhinia lotus nepalensis Muell.-Arg., Carya cathayensis Sarg., Mil pernervosa L. Chen, Schefflera delavayi (Franch.) Harms. lettia speciosa Champ. Lactuca indica L., Begonia yunnan Endospermum chinense Benth., Gelsemium elegans Benth. ensis Levl., Codonopsis lanceolata Benth. et Hook. Lobelia Mariscus umbellatus Vahl, Polia acilisia Hassk. Ligularia sessilifolia Lamb., Tricyrtis pilosa wall. Clausena excavata lapathifolia (Franch.) Hand.-MaZZ. Vaccinium dunalianum Burm. f. Dianella ensifolia (L.) DC., Alchornea davidi wight. Var, urophyllum Rehd. et wils. Gaultheria forrestii Franch. Psilopeganum sinense Hemsl., Zingiber mioga Diels, Polistes mandarinus Sauss., Torricellia angulata Oliv. Rose. Pellionia minima Mak. Zanthoxylum dissitum Hemsl., var. intermedia (Harms) Hu, Hydrocotyle javanica Thunb. Clitoria hanceana Hemsl., Crataegus pinnatifida Bge. Var. var. Chinensis Dunn ex Shanet Liou, Rhynchoglossum obliq major N. E. Br. C. cuneata Sieb. et Zucc., Crataegus Oxya uum Bl. Elsholtzia penduliflora w.w. Smith, Stellaria pani cantha, C. monoguna, Carex baccans Nees, Rhodomyrtus culigera Mak. Mallotus barbatus (wall.) Muell.-Arg. Thal tomentosa (Ait.) Hassk. Cremastra variabilis (Bl.) Nakai, ictrum faberi Ulbr., Anaphalis margaritacea (L.) Benth. et Pleione yunnanensis (Rolfe) Rolte, Oreorchis patens (Lindl.) Hook.f., Stenolomachusanum (L.) Ching, Ophiopogon dra Lindl., O. foliosa Lindl., Orthosiphon wulfenioides (Diels) caenoides (Bak.) Hook. f. Uncaria macrophylla wall. Hand.-MaZZ., Rhus delavayi Franch. Prunus tomentosa Indigofera teysmannii Miq., Isodon nervosus (Hemsl.) Kudo, Thunb., Fortunella hindsi (Champ.) Swingle, Dracoceph Euonymus grandiflorus wall. Bauhinia pernervosa L. Chen, alum moldavicum L., Lindera reflexia Hemsl., Teucrium vis Chone morpha megacalyx Pier. Clematis argentilucida cidum Bl. Teucrium scorodonia, Gutzlafia aprica Hance, (Levl. et Vant.) w.T. wang, Moghania macrophylla (wild.) O. Psychotria rubra (Lour.) Poir. Vigna vexillata (L.) Benth. Ktze. Zanthoxylum dissitum Hemsl., Indigofera teysmannii var. yunnanensis Franch., Vigna vexillata Benth., Viburnum Miq., Moghania bracteata (Roxb.) Li, Crepis lignea (Van.) foetidum wall. var. Ceanothoides (C.H. wright) Hand.-MaZZ. Babc., Lycopodium pulcherrimum wall. Tagetes erecta L., Fimbristylis fisca (Nees) Benth., Sapium discolor (Champ.) Tagetes minuta (T. glanduliflora), Rohdea japonica Roth, Muell.-Arg. Mussaenda pubescens Ait. f. Musa paradisia Crepis lignea (Van.) Babc., Viola diamantiaca Nakai, Cli cal L. Subsp. Seminifera (Lour.) K. Schum. Evodia tri US 2009/01 04295 A1 Apr. 23, 2009

chotoma (Lour.) Pier. Ilex franchetiana Loes. Acronychia Szemoensis Gagn. Stachyurus himalaicus Hook. f. et pedunculata (L.) Miq., Lindera glauce (Sieb. et Zucc.) Bl. Thoms. Stachyurus chinensis Franch. S. yunnanensis Cudrania cochinchinensis (Lour.) Kudo et Masam., Cassia Franch. S. obovatus (Rehd.) Li, S. retusus Yang, S. Szechua minosoides L., Pleomele Cambodiana (Gagn.) Merr. et Chun, mense Fang, S. Salicifolius Franch. Spilanthes callimorpha Cardiocrinum giganteum (wall.) Mak. Rhynchosia dielsii A. H. Moore, Vicia hirsute (L.) S. F. Gray, Polygonum ple Harms, Vicia amoena Fisch., Vicia Cracca L. V. pseudo beium R. Br., Cladonia verticillata Hoffm., Sanicula astran Orobus Fisch. et Mey. Artemisia cina Berg., Cremastra vari tifolic wolff ex Kreschmer, Aleuritopteris kuhni (Milde) abilis (Bl.) Nakai, Pleione bulbocodioides (Franch.) Rolfe, Ching, Sedum bulbiferum Mak., Haloragis micrantha R.Br. Prunus tomentosa Thunb., Swertia punicea Hemsl., Vitis Tetrastigma Obtectum (wall.) Pl. Var. glabrum Gagn. Berb amurensis Rupr., Acronychia pedunculata (L.) Miq., Phila eris wilsonae Homsl., Sinocrassula sp., Euphorbia thymifolia delphus sericanthus Koehne, Gomphrena globosa L., L., Arenaria serpyllifolia L., Rubus parkeri Hance, Asple Moghania philippinensis (Merr. et Rolfe) Li, Lindera chunii nium pekinense Hance, Gentiana rhodantha Franch. Pho Merr., Homalomena occulta (Lour.) Schott, Senecio scan tinia parvifolia (Pritz.) Schneid, Rhododendron capitatum dens Buch.-Ham..., Lycopodium serratum Thunb., Lycopo Maxim. Rhododendron anthopogonoides Maxim. Agapetes dium serratum Thunb. Var, thunbergii, Euphorbia lathyris L., mannii Hemsl., Morus australis Poir. Ziziphora clinopodio E. amygdaloides, Eupatorium fortunei Turcz., Stephania ides Lam., Striga masuria (Buch.-Ham.) Benth. Selaginella japonica (Thunb.) Miers, Lythrum salicaria L., Lythrum davidii Franch. Lysimachia congestifloa Hemsl., Gardneria anceps Mak. Tinospora crispa (L.) Miers, Stellaria yunnan angustifolia wall. Boehmeria spicata (Thunb.) Thunb. ensis Franch. Semiaquilegia adoxoides (DC.) Mak. Ligus Sopubia trifida buch.-Ham. Cyclea racemosa Oliv., Eragros ticum wallichii Franch. Cnidium officinala mak. Clematis tis Poaeoides Beauv., Veronica javanica Bl., Oreocharis fla armandi Franch. Clematis Montana Buch.-Ham... Clematis vida Merr., Dichondra repens Forst. Rosa cymosa Tratt. apiifolia D. C., C. henryi Oliv., C. pavoliniana Pamp., C. Aletris spicata (Thunb.) Franch. Aletris glabra Bureau et lesehenaultiana D. C., C. armandi Franch. var. biondiana Franch. Breynia patens (Roxb.) Benth. Cucubalus baccifer (Paval.) Rehd., C. gouriana Roxb. Var. finetii Rehd. et wils. L., Lespedeza tomentosa (Thunb.) Sieb., Lespedeza capitata, Fritillaria cirrhosa D. Don, Fritillaria cirrhosa D. Don var. Ampelopsis humulifolia Bge, Lycopodium selago L., Iris col ecirrhosa Franch. Fritillaria delavayi Franch. Fritillaria lettii Hook.f., Tripterospermum coeruleum (Hand.-MaZZ. ex przewalskii Maxim, Fritillaria ussuriensis Maxim. Fritill H. Sm.) H.Sm. Clematis gouriama Roxb. var. finetii Rehd. et laria pallidiflora Schreb., Fritillaria maximowiczii Freyn, wils. Croton lachnocarpus Benth. Dasiphora parvifolia Fritillaria roylei Hook. Cyathula officinalis Kuan, Cyathula (Fisch.) Juz., Onychium japonicum (Thunb.) Kunze, Isodon capitata (wall.) Moq., Aconitum carmichaeli DebX., Aconi amethystoides (Benth.) C.Y. wu et Hsuen, Carpinus cordata tum japonicum Nakai, Ligusticum brachylobum Franch. B1. Var. Chinensis Franch. Cardiospermum halicacabum L. Cheilanthes chusana Hook. Melia toosendan Sieb. et Zucc., var. microcarpum (Kunth) Bl. Dryoathyrium Okuboanum Melia azedarach L., Chloranthus serratus (Thunb.) Roem. et (Mak.) Ching, Carduus crispus L., Carduus acanthoides L., Schult. Serratula chinensis S. Moore, Eupatorium chinense Eupatorium odoratum L., Cynanchum auriculatum Royle ex L., Desmodium Styracifolium (Osbeck) Merr., Clematis apii wight, Consolida ajacis (L.) Schur, Delphinium elatum, folia D.C., Aster fastigiatus Fisch. Rhamnus heterophylla Pothos repens (Lour.) Merr., Cyathea spinulosa wall. Tod Oliv., Ligustrum lucidum Ait. Melandrium apricum (Turcz.) dalia asiatica (L.) Lam., Stellaria dichotoma L., Equus Rohrb., Berchemia yunnanensis Franch. Triticum aestivum cabalus (L.), Kalimeris indica (L.) Schulz-Bip. Equus L., Lysimachia deltoidea wight var. cinerascens Franch. cabalus (L.), Prospirobolus ioannsi (Brolemann), Equus Polygala tenuifolia wild. Allium scorodoprasum L., Ceph cabalus (L.), Lasiosphaera fenzli Reich., Calvatia alanoplos segetum (Bge.) Kitam. Cephalanoplos setosum gigantean (Batsch ex Pers.) Lloyd, Calvatia lilacina (Mont. (Bieb.) Kitam. Berberis amurensis Rupr., Berberis poiretii &Berk.) Lloyd, Lycoperdon gemmatum Batsch. Setaria pli Schneid., Berberis thunbergii DC., Berberis wilsonae cata (Lamk.) T Cooke, Equus cabalus (L.), Digitaria San Hemsl., B. Sibirica Pall., B. anhweiensis Ahrendt., B. Sub guinalis (L.) Scop., Equus cabalus (L.), Solen gouldii acuminata C. K. Schneid., B. vulgaris L., Polygala Sibirica L. Conrad, Nothapodytes pittosporoides (Oliv.) Sleum. Calan var. megalopha Fr. Codonopsis cardiophylla Diels, Veratrum the fimbriata Franch. Pedicularis resupinata L., Thalictrum mengtzeanum Loesen. f. Clematis lasiandra Maxim. Millet foliolosum DC., Thalictrum baicalense Turcz, Thalictrum tia pulchra Kurz var. typical flaxior Dunn., Leontopodium foetidum L., T. cultratum wall. T. chaotungensis W.T. Wang et japonicum Miq., Pyrrosia assimilis (Bak.) Ching, Salix hypo S. H. Wang, T. baicalense Turcz. Var. megalostigma Boivin, leuca Seem. Morus australis Poir. Aconitum bullatifolium Hydrocharis asiatica Miq., Sambucus buergeriana Bl. Levl. Aconitum pulchellum Hand.-MaZZ. Tilophora yun Portulaca oleracea L., Embelia oblongifolia Hemsl., Strych manensis Schltr., Lindernia munularifolia (D. Don) wettst. nos nux-vOmica L., Strychnos pierriana A. W. Hill, Coriaria Asparagus officinalis L., Pittosporum floribundum wight et sinica Maxim. Aristolochia contorta Bge., Melothria indica Arm. Schisandra propinqua (wall.) Baill. Var. Sinensis Oliv., Lour. Butea suberecta (Dunn) Blatter. Butea suberba, B. Actinidia purpurea Rehd., Euphrasia regelii wettst. Lyonia frondosa, Nephrolepis cordifolia (L.) Presl, Capparis ptero ovalifolia (wall.) Drude, Polygonum chinense L. var. hispi carpa Chun, Capparis masaikai Levl., Capparis versicolor dum Hook. f. Salvia coccinea L., Rubia yunnanensis Griff, Iris pallasii Fisch. var. chinensis Fisch. Iris halophila (Franch.) Diels, Parthenocissus himalayanaa (Royle) Pall. Rhododendron delavayi Franch. Ipomoea pes-Caprae Planch. Triticum aestuvum L., Micromelum integerrimum (L.) Sweet, Cotoneaster amoena wils., Caltha palustris L., (Ham.) Roem. Hypericum erectum Thunb., Ardisia punctata Caltha Scaposa Hook. f. et Thoms. Equus cabalus (L.), Lindl., Populus pseudo-Simonii Kitag., Inula Cappa D. C., Caltha palustris L. var. membranacea Turcz., Angiopteris Rosa cymosa Tratt. Jasminum floridum Bge. Breynia patens fokiensis Rieron. Verbena officinalis L., Camptosorus Sibiri (Roxb.) Benth., Leptadina retticulata, Delphinium yunnan cus Rupr., Equus Cabalus (L.), Sedum emarginatum Migo, ense Franch. Delphinium delavayi Franch. Crotalaria Sedum makinoi Maxim. Hydrangea davidii Franch. Smilax US 2009/01 04295 A1 Apr. 23, 2009

nipponica Miq., Portulaca oleracea L., Coriaria sinica fordiana (Hemsl.) Oliv., Akebia quinata (Thunb.) Decne. A. Maxim. Ipomoea pes-Caprae (L.) Sweet, Saussurea cordifo trifoliata (Thunb.) Koidz., A. trifoliata (Thunb.) Koidz. var. lia Hemsl., Lycopodium sieboldii Miq., Trichosanthes australis (Diels) Rehd., Mahonia Shenii Chun, Mahonia cucumeroides (Ser.) Maxim. Trichosanthes cucumeroides Schochii Schneid. ex Hand.-MaZZ., M. Subimbricata Chun et Maxim. Thladiantha dubia Bge. Paris tetraphylla A. Gray, F. Chun, M. taronensis Hand.-MaZZ., Litsea pungens Hemsl., Trichosanthes cucumeroides (Ser.) Maxim. Vacaria segetalis GomphoStemma microdon Dunn, Gossampinus malabarica (Neck.) Garcke, Melandrium apricum (Turcz.) Rohrb. Vac (D.C.) Merr., Ficus pumila L., Hibiscus Syriacus L., Oroxy caria Segetalis (Neck.) Garcke. Pteris laeta (wall.) Ching, lum indicum (L.) Vent. Momordica Cochinchinensis (Lour.) Anoplophora chinensis (Frster), Apriona germari (Hope), Spr., Actinidia polygama (Sieb. et Zucc.) Miq., Elaeagnus Allium finckiaefolium Hand.-MaZZ. Gastrodia etata B1. multiflora Thunb., Garcinia oblongifolia Champ. Hibiscus Semiaquilegia adoxoides (D C.) Mak. Asparagus mutabilis L., Litsea pungens Hemsl., Viburnum macroceph cochinchinensis (Lour.) Merr., Asparagus filicinus ex D. Don alum Fort. Viburnum opulus, V. prunifolium, Oroxylum indi Ham..., A. meioclados Levl. A. spinasissimus wang et S. C. cum (L.) Vent. Lespedeza buergeri Miq., Pseudostellaria Chen, Asparagus racemosus, Triosteum pinnatifidum heterophylla (Miq.) Pax ex Pax et Hoffm., Pseudostellaria Maxim. Spilanthes acmella (L.) Murr., Diuranthera minor Maximowicziana (Franch. et Savat.) Pax ex Pax et Hoffm. (C. H. Wright) Hemsl., Hyoscyamus niger L., Hygrophila Rubus pacificus Hance, Tanacetum variifolium (Chang) Ling, salicifolia (Vahl) Nees, Aristolochia debilis Sieb. et Zucc. Cladonia alpestris (L.) Rabht. Pedicularis davidii Franch. Aristolochia contorta Bge., Carpesium abrotanoides L., Tri Pedicularis rudis Maxim., Pedicularis dunniana Bonati, chosanthes kirilowii Maxim. Solanum indicum L., Physalis Peicularis decora Franch. Aster flaccidus Bge. Plagiopus minima L., Hydrocotyle Sibthorpioides Lam., Arisaema con oederi (Brid.) Limpr., Tetraplodon bryoides (Zoeg.) Lindb. sanguineum Schott, Arisaema amurense Maxim. Arisaema Tongoloa dunnii (Boiss.) wolff, Fritillaria taipaiensis P.Y. Li, Heterophyllum Bl. Arisaema ambiguum Engl. Arisaema Cladonia gracilis (L.) willd. Cremanthodium hookerii peninsulae Nakai, Arisaema thunbergii Bl., Arisaema verru Clarke, Rubus blinii Levl., Ipomoea cairica (L.) Sweet, Anti cosum Schott, Arisaema lobatum Engl. Var. rosthornianum desma bunius (L.) Spr., Anaphalis hancockii Maxim. Ficus Engl. Arisaema elephas S. Buchet, Osbeckia chinensis L., simplicissima Lour. var. hirta (Vahl.) Migo, Rubus Metaplexis japonica (Thunb.) Mak. Lufa cylindrical (L.) cochinchinensis Tratt. Acanthopanax gracilistylus W. W. Roem. Aucuba chinensis Benth., Gastrodia elata Bl. Semi Smith, A. sessiliflorus (Rupr. et Maxim.) Seem. A. senticosus aquilegia adoxoides (D.C.) Mak. Stellaria alsine Grimm. (Rupr. et Maxim.) Harms. Acanthopanax henryi (Oliv.) Sorbus tianschanica Rupr., Triosteum pinnatifidum Maxim. Harms, Acanthopanax verticillatus Hoo, Acanthopanax Gnaphalium hypoleucum DC., Magnolia amoena Cheng, giraldi Harms, A. trifoliatus (L.) Merr., A. evodiaefolium Magnolia cylindrical wils., Gnaphalium japonicum Thunb. Franch. var. ferrugineus W. W. Smith, A. Setchuenensis Harms, Fagopyrum cynosum Meisn., Aucuba chinensis Benth., Gas A. leucorrhizus (Oliv.) Harms, Periploca sepium Bge. Lan trodia elata Bl. Triosteum pinnatifidum Maxim. Litsea tana camara L., Chrysomyia megacephala (Fab.), Tro auriculata Chien et Cheng, Cassytha filiformis L., Pistacia gopterus xanthipes Milne-Edwards, Triosteum fargesii vera L., Pyrolusite, Ficus carica L., Ampelopsis cantoniensis Franch. Schisandra chinensis (Turcz.) Baill. Schisandra (Hook. et Arm.) Planch. Sapindus mukorossi Gaertn., Phoe sphenanthera Rehd. et wils. Corydalis Stenantha Franch. nix dactylifera L., Pistacia vera L., Ficus carica L., Sapindus Echinopsilon divaricatum Kar. et Kir. Mosla Soochouensis mukorossi Gaertn., Prunus brachypoda Batal. Var. eglandu Matsuda, Schisandra propinqua (wall.) Bail. Var. intermedia losa Cheng, Scutellaria indica. L. var. humilis Mak., Hyperi A. C. Smith, Evodia trichotoma (Lour.) Pier. Rhus chinensis cum Sampsonii Hance, MuSXovitei, Caesalpinia sepiaria Mill., R. potaninii Maxim. R. punjabensis Stew. Var. Sinica Roxb., Caesalpinia bonducella, Achyranthes aspera L. var. (Diels) Rehd. et wils., Melaphis chinensis (Bell), Melaphis rubrafisca (wight) Hook. Caesalpinia sepiaria Roxb. paitan Tsai et Tang, Tetrastigma hypoglaucum Planch. Lan elphinium giraldi Diels, Caesalpinia sepiaria Roxb., Rubia tana camara L., Acer Sinense Pax, Acer Sinopurpurascens yunnanensis (Franch.) Diels, Asbestus, Chaenomeles lage Cheng, A. henryi Pax, A. palmatum Thunb., Abelmoschus naria (Loisel.) Koidz., Chaenomeles sinensis (Thouin) Koe Sagittifolius (Kurz) Merr., Kadsura longipedunculata Finet, hne, C. lagenaria (Loisel.) Koidz. var. Cathayensis Rehd., C. Schisandra sphenanthera Rehd. et wils. Kadsura coccinea lagenaria (Loisel.) Koidz. var. wilsonii Rehd., C. thibetica (Lem.) A. C. Smith, Schisandra propinqua (wall.) Hook fet Yw, Auricularia auricula (L. ex Hook.) Underw. Cajanus Thoms, Rhus chinensis Mill. Loranthus pentapetalus Roxb. cajan (L.) Millsp., Saussurea lappa Clarke, Vladimiria den Geum aleppicum Jacq., Ipomoea cairica (L.) Sweet, Pedicu ticulata Ling, Vladimiria Souliei (Franch.) Ling, Vladimiria laris rex C. B. Clarke ex Maxim. Vitis quinquangularis muliensis (Hand.-MaZZ.) Ling, V. edulis (Franch.) Ling, Rehd., Ficus simplicissima Lour., Melaphis chinensis (Bell), Schima superba Gardn. et Champ. Equisetum Hiemale L., E. M. paitan Tsai et Tang, Choerospondias axillaries (Roxb.) arvense L., Akebia trifoliata (Thunb.) Koidz. var. custralis Burtt et Hill, Meconopsis quintuplinervia Reg., Lepisorus (Diels) Rehd., Akebia trifoliata (Thunb.) Koidz., Akebia thunbergianus (Kaulf.) Ching, Orostachys fimbriatus quinata (Thunb.) Decne. Aristolochia manshuriensis Kom. (Turcz.) Berger, Orostachys erudescens (Maxim.) Ohwi, Clematis armandi Franch., C. montana Buch.-Ham. Aris Orostachys spinosus (L.) C. A. Mey. Melandryun viscidulum tolochia kaempferi willd.; A. moupinensis Franch. Akebia (Franch.) Hand.-Mazz. var. Szechuanense (wills.) Hand.- quinata (Thunb.) Decne. Akebia longeracemosa Matsum, MaZZ., Arca inflata Reeve, A. granosa L., A. subcrenala Lis Indigotera tinctoria L., Actinidia polygama (Sieb. et Zucc.) chke, Plantago asiatica L., Plantago depressa willd. Plan Miq., Chaenomeles lagenaria (Loisel.) Koidz. Magnolia lili tago major L., Plantago Ovata, Dodonaea viscose (L.) Jacq., flora DeSr., Elaeagnus multiflora Thunb., Garcinia Oblongi Oldenlandia uncinella (Hook. et Arn.) O. Ktze. Var. scabrida folia Champ., Cajanus Cajan (L.) Millsp., Litsea pungens (Franch.) Chun, Cynoglossum lanceolatum Forsk. Gynura Hemsl., Litsea cubeba (Lour.) Pers., L. euosma W. W. Smith, Sagittata D.C., Hollarrhena antidysenterica wall. Fimbristy Elsholtzia cypriani (Pamp.) C.Y. wu et S. Chow. Manglietia lis miliacea (L.) Vahl, Monetaria moneta (L.), Monetaria US 2009/01 04295 A1 Apr. 23, 2009

annulus (L.), Coelogyne corymbosa Lindl., Zanthoxylum nifolia (Sieb. et Zucc.) Villar, Clerodendron vunnanense Hu dimorphophyllum Hensl. var. spinifolium Rehd. et wils. ex Hand.-MaZZ., Corvus macrorhynchus wagler, Gallus gal Liparis nervosa (Thunb.) Lindl., Anaphalis bulleyana (J. F. lus domesticus Brisson, Fissistigma glaucescens (Hance) Jaffr.) Hand.-Mazz., Bos taurus domesticus Gmelin, Bubalus Merr., Sapium sebiferum (L.) Roxb., Periploca calophylla bubalis L., Aconitum ochranthum Mey., Achyranthes biden (wight) Falc., Canarium pimela Koenig, Cayratia japonica tata Bl. Mucuna sempervirens Hemsl., Oreas martiana (Thunb.) Gagn. Cayratia japonica (Thunb.) Gagn. Var. pubi (Hopp. et Hornsch.) Brid. Heleocharis yokoscensis (Franch. folia Merr. et Chun, Viola vaginata Maxim. Rubus tephrodes et Savat.) Tang et wang, Oldenlandia hedyotidea (D C.) Hance, Gentiana urnula H. Sm. Corvus macrorhynchus Hand.-MaZZ., Elaeagnus umbellate Thunb., Ficus hispida L. wagler, Sepiella maindronide Rochebrune, Sepia Esculenta f. Ficus beecheyana Hook. et Arm. Rumex patientia L., Hoyle, Oenothera erythrosepala borb., Rosa Chinensis Jacq., Didymocarpus eburneus (Hance) Levl. Boea hygrometrica Laurus nobilis L., Salvia militiorrhiza Bge. Salvia przewal (Bge.) R. Br. Sonchus arvensis L., Rumex dentatus L., Sida skii Maxim. S. przewalski Maxim. Var. mandarinorum (Di retusa L., Lygodium flexuosum (L.) Sw., Dodartia Orientalis els) Stilb., S. yunnanensis C. H. wight, Ficus martini Levi. et L., Rubus ichangensis Hemsl. et O. Ktze. Smilax riparia A. Vant. Dioscorea japonica Thunb., Hiptage benghalensis (L.) DC., Circaea cordata Royle, Alnus lanata Duthie, Eleusine Kurz, Adenostemma lavenia (L.) O. Ktze., Rorippa palustris indica (L.) Gaertn., Arctium lappa L., Fortunearia sinensis (Leyss.) Bess., Clinopodium chinense (Benth.) O. Ktze. Rehd. et wils. Cerbera manghas L., Oldenlandia hedyotidea Cephalanthus Occidentalis L., Clematis chrysocoma Franch. (D.C.) Hand.-Mazz., Ficus hispida L.f., Ficus beecheyana Impatiens balsamina L., Rhodiola dumulosa (Franch.), Hook. et Arm. Rumex crispus L. Rumex nepalensis Spr., Pedicularis henryi Maxim. Pedicularis longicaulis Franch. Daphniphyllum calycinum Benth. Arctium lappa L., Sau et Maxim. Pteris multifida Poir. Elsholtzia bodinieri Vant, rauia lantsangensis Hu, Saurauia napaulensis D.C., Achy Pteris ensiformis Burm. Sterculia nobilis Smith, Ailanthus ranthes bidentata B1. Rumex Crispus L., Aleurites fordii altissima (Mill.) Swingle, Gallus gallus domesticus Brisson, Hemsl., Gymnadenia Conopsea R.Br., Gymnadenia crassin Polystichum acanthophyllum (Fr.) Bedd. Cycas revolute ervis Finet, Coeloglossum viride (L.) Hartm. Var. bracteatum Thunb., Sterculia nobilis Smith. Asplenium yunnanense (wild.) Richter, Ranunculus japonicus Thunb., Lycianthes Franch. Arthromeris mairei (Brause) Ching, Caryopteris biflora (Lour.) Bitter, Phyllostachys pubescens Mazel ex H. terniflora Maxim. Viburnum propinquium Hemsl., Rhodo de Lehaie, Melastoma sanguineum Sims, Polygonum barba dendrom mole (Bl) G. Don, Iris speculatrix Hance, Eupato tum L., Dioscorea alata L., Clematis argentilucida (Levl. et rium chinense L., Asparagus plumosus Bak. Meretrix mer Vant.) W. T. Wang, Populus tomentosa Carr. Actinidia erian etrix L., Xanthoceras Sorbifolia Bge. Cypsilurus agoo tha Benth. Ilex pubescens Hook. et Arm. Ilex pubescens (Temm. et Schl.), Crinum asiaticum L. var. Sinicum Bak, Hook. et Arm. Var. glabra Chang, Picris hieracioides L. Calcite, Sus scrofa domestica Brisson, Helicteres isora L., Subsp. fiscipilosa Hand.-MaZZ. Ardisia pusilla D/C., Dry Euphorbia antiquorum L., Cannabis sativa L., Aconitum opteris championi (Benth.) C. Chr. ex Ching, Adonis Sze sungpanense Hand.-MaZZ., Polygonum chinense L., P chin chuenensis Franch. Verbascum thapsus L., Adenosma gluti ense var. thunbergianum, Streptocaulon griffithii Hook. f. nosum (L.) Druce, Dysosma hispida (Hao) Chun, Gerbera Euphorbia antiquorum L., Tupistra pachymena wang et piloselloides Cass., Philadelphus henryi Koehne, Croton Tang, Epilobium pyrricholophum Franch. et Sav., Viburnum caudatus Geisel. Var. tomentosus Hook. Nanocnide pilosa cordifolium wall. et D. C., Croton tiglium L., Solanum indi Migo, Cornus walteri wanger. Desmodium elegans (Lour.) cum L., Miscanthus floridulus (Labill.) warb. Morinda offi Benth., Gerbera piloselloides Cass., Lindera caudate (wall.) cinalis How, Morinda citrifolia, M. tictoria, Morinda lucida, Benth., Photinia villosa (Thunb.) DC., Meconopsis quintu Prunus amygdalus Batsch. Prunus amygdalus Batsch var. plinervia Reg., Leptodermis pilosa (Franch.) Diels, Gera dulcis Schneider, Pamygdalus Batsch var.amara Schneider, nium eriostemon Fisch. Cimicifuga foetida L., Cimicifiiga Triplostegia grandiflora Gagn. Habenaria dentate (Sw.) dahurica (Turcz.) Maxim. Cimicifiiga heracleifolia Kom. Schltr., Microtis taiwaniana Schltr., Bauhinia hupehana Serratula chinensis S. Moore, Aruncus Sylvester Kostel. Craib, Aubskuaea carduiophylla Franch. Elsholtzia fruticosa Anhydrite, Lepisorus psedonudus Ching, Arundina chinensis (D. Don) Rehd., Ceropegia dolichophylla Schltr., Christia B1. Seseligiraldii Diels. Catharanthus roseus (L.) G. Don. vespertilionin (L. f.) Bahn. F., Asplenium sarelii Hook. Tag Catharanthus roseus (L.) G. Don var. albus (Sweet) G. Don, etes patula L., Oenanthe javanica (Bl.) DC., Stachys C. roseus (L.) G. Don var. flavus (Tsiang) Metcalf, Vinca baicalensis Fisch. Stachys recta L., Stachy's neglecta Klok. minor L., Vinca erecta Rgl. et Schmach, Platanthera Stachys betonicaeflora, Codium fragile (Sur.) Har., Solanum japonica (Thunb.) Lindl., Callicarpa loureiri Hook. et Arm. torvum Sw., Hydrotrechus remigator Hor. Gardenia jasmi Helicteres elongata wall. Pedicularis longiflora Rudolph. noides Ellis var. grandiflora Nakai, Gardenia jasminoides var. tubiformis (Klotz.) Tsoong, Clerodendron indicum (L.) Ellis var. radicans Mak. Enhydris chinensis (Gray), Cinna O. Ktze. Cymbidium faberi Rolfe, Melasma arvense (Benth.) bar, Mercury, Scirpus validus Vahl, Hirudo nipponia whit Hand.-MaZZ., Crotalaria tetragona Roxb., Citrus grandis man, whitmania Pigra (whitman), whitmania acranulata (L.) Osbeck var. tomentosa Hort. Citrus grandis (L.) Osbeck, (whitman), whitmania edentula (whitman), Polygonum Platycarya Strobilacea Sieb. et Zucc., Platycarya longipes hydropiper L., Ceratopteris thalictroides (L.) Brongn. Lud wu, Schizothorax yunnanensis Norman, Juglans regia L., wigia prostrata Roxb. Begonia pedatifida Levl., Mnium cus Lindera Strychnifolia (Sieb. et Zucc.) Villar, Corvus macro pidatum Hedw. Bubalus bubalis L., Polypodium niponicum rhynchus wagler, Prunus mume (Sieb.) Sieb. et Zucc., Zaocys Mett. Polypodium vulgare L., P. pseudoamoenum Ching, dhumnades (Cantor), Canariumpinela Koenig, Tarenna mol Tacca plantaginea (Hance) Prenth. Tacca chantrieri Andre, lissima (Hook. et Arn.) Robins. Diospyros ebenum Koen. Boehmeria grandifolia wedd., Narcissus tazetta L. var. chin Sophora mairei Pamp. Vaccinium fragile Franch. Swertia ensis Roem. Jussiaea suffruticosa L., Narcissus papy raceus heterantha Ling, Sepiella maindroni de Rochebrune, Sepia Ker-Gaw, Ligustrum quihoui Carr., Ligustrum sinense Lour. esculenta Hoyle, Salix microstachya Turcz., Lindera Strych var. Initidum Rehd., Cardiocrinum cathayanum (wils.) Mak., US 2009/01 04295 A1 Apr. 23, 2009

Adina pilulifera (Lam.) Franch. Murdannia triguetra (wall.) rum sinensis Roxb., Dioscorea esculenta (Lour.) Burkill, Brcckn. Lysimachia Stenosepala Hemsl., Lysimachia circae Glycyrrhiza uralensis Fisch. Musa paradisiaca L. var. sapi Oides Hemsl., Homonoia riparia Lour. Salix purpurea L., entum (L.) O. Ktze. Oxytropis kansuensis Bge., Atractylodes Geum japonicum Thunb., Adina rubella (Sieb. et Zucc.) macrocephala Koidz., Arachniodes amabilis (Blume) Tin Hance, Limnophila aromatica (Lam.) Merr., Rotala rotundi daler Pyrrosia lingua (Thunb.) Farw. Pyrrosia sheareri folia (Buch.-Ham.) Koehne, Ammannia baccifera L., Oenan (Bak.) Ching, Pyrrosia drakeana (Franch.) Ching, Pyrrosia the benghalensis (Roxb.) Kurz, Stachys baicalensis Fisch. petiolosa (Christ) Ching, Pyrrosia davidii (Gies.) Ching, Pyr Gymontheca involucrata Pei, Cassia nomame (Sieb.) Kita rosia gralla (Gies.) Ching, Umbilicaria esculenta (Miyoshi) gawa, Saurauia tristyla DC., Glyptostrobus pensilis (Lamb.) Minks, Limestone, Gorgonia flabellum L., Parmelia saxatilis K. Koch, Veronica anagallis-aquatica L., Impatiens uligi Ach. Parmelia saxatilis var. Omphalodes, Bulbophyllum nosa Franch., Penthorum chinense Pursh, Oldenlandia radiatum Lindl., Phryganea japonica Ml., Ulva lactuca L., corymbosa L., Myricaria germanica (L.) DesV. Cleroden Ulva pertusa Kjellm., endrobium nobile Lindl., Dendrobium dron inerme (L.) Gaertn., Limnophila rugosa (Roth) Merr., linawianum Reichb.f., Dendrobium officinale K. Kimura et Nitella expansa Allen, Cotoneaster horizontalis Decne. Migo, Dendrobium moniliforme (L.) Sw., Dendrobium her Cyperus glomeratus L., Cleistocalyx operculatus (Roxb.) coglossum Reichb.f. Dendrobium aduncum wall. et Lindl., Merr. et Perry, Pongamia pinnata (L.) Merr., Potamogeton Dendrobium wilsonii Rolfe, Dendrobium hancockii Rolfe, natans L., Gardenia jasminoides Ellis var. grandiflora Nakai, Dendrobium lohohense Tang et wang, Dendrobium loddige Actinidia callosa Lindl. Var. henryi Maxim. Polygonum thun sii Rolfe, Dendrobium bellatulum Rolfe, P590, Lycoris bergii Sieb. et Zucc., Pilea notata C. H. wright, Oreocnide radiata (LHer.) Herb., Lycoris squamigera Maxim. Mitella frutescens (Thunb.) Mig. Anemone hupehenis Lem.f.albaw. mitella (L.), Cypsum, Cladonia rangiferina web., Sarco T. Wang, Inula helianthus-aquatilis C. Y. Wu ex Ling, Eich cheilichthys sinensis Bleeker, CyrtioSpirifer sinensis (Gra hornia Crassipes Solms, Lactuca raddeana Maxim. Var. elata ban.), Mycoblastus alpinus (Fr.) Kernst., Telphusa sp., Chiton (Hemsl.) Kitam. Monotropa uniflora L., Chloranthus fortu sp., Ludisia discolor (Ker-Gawl.) A. Rich., Pyrrosia lingua nei (A. Gray) Solms, Neosalanx tankankei taihuensis Chen, (Thunb.) Farw. Salvia chinensis Benth., Goodvera procera Sorbus alnifolia (Sieb. et Zucc.) K. Koch, Kyllinga brevifolia (Ker-Gawl.) Hook. Eumeces chinensis (Gray), Eumeces Rottb., wendlandia uvariifolia Hance, Sagittaria aginashi elegans Boulenger, Sphenomorphus indicus (Gray), Juncus Mak. Apluda mutica L., Polygonum hydropiper L., Ficus efuses L. var. decipiens Buchen. f. utilis Mak. Ranunculus Stenophylla Hemsl., Ligularia sp., Isodon adenanthus (Diels) sceleratus L., Gontiana squarrosa Ledeb., Pholidota chinen Kudo, Tacca plantaginea (Hance) Prenth. Polygonum Orien sis Lindl., Lysionotus pauciflora Maxim. Haliotis diversi tate L., P. lapathifolium L., P. lapathifolium L. var. Salicifo color Reeve, Haliotis gigantea discus Reeve, Elatostema lae lium Sibth., Salix purpurea L., Geum japonicum Thunb. vigatum (Bl.) Hassk. Peucedanum terebinthaceum (Fisch.) Adina rubella (Sieb. et Zucc.) Hance, Phragmites karka Fisch. ex Turcz., Eucheuma gelatinae (Esp.) J. Ag., Chlamy (Retz.) Trin. Adina pilulifera (Lam.) Franch. Cassia doboea sinensis (Oliv.) Stapf, Lycopodium clavatum L., nomame (Sieb.) Kitagawa, Saurauia tristyla DC., Veronica Lycopodium obscurum L., L. complanatum L., L. alpinum L., anagallis-aquatica Li. Clerodendron inerme (L.) Gaertn., L. annotinum L., Pilea cavaleriei Levl., Psilotum nudum (L.) Lindernia antipoda (L.) Alston, Hymenocallis americana Griseb., Pothos chinensis (Raf.) Merr., Photinia serrulata Roem. Hymenocallis speciosa, Polygala caudate Rehd. et Lindl., Rhododendron metternichii S. et Z., Hoya lyi Levl. wils., Epilobium hirsutum L., Torenia glabra Osbeck, Inula Mosla scabra (Thunb.) C.Y. wu. et H. W. Li, Sedum sarmen helianthus-aquatilis C. Y. Wu ex Ling, Cacalia tangutica tosum Bge. Mosla chinensis Maxim. Corallodiscus flabel (Maxim.) Hand.-MaZZ., Halerpestes Sarmentosa (Adams) lata (Franch.) B. L. Burtt, Pseudosciaena crocea (Rich.), Kom. Cardamine lyrata Bge. Ligustrum quihoui Carr. Salix Pseudosciaena polyactis Bleeker, Lepisorus eilophyllus (Di purpurea L., Veronica anagallis-aquatica L., Impatiens uligi els) Ching, Polygonum capitatum Ham. ex D. Don, Aleurites nosa Franch. Epilobium palustre L. Vittaria flexuosa Fee, moluccana (L.) willd. Petroleum, Acorus gramineus Polygonatum odoratum (Mill.) Druce var. pluriflorum (Miq.) Soland. Acorus gramineus Soland. Var. pusillus Engl. Ohwi, Polygonatum macropodium Turcz., Polygonatum Anemone altaica Fisch. Berchemia hypochrysa Schneid. involucratum Maxim. Polygonatum inflatum Komar. Lyco Dendrobium nobile Lindl., Stereocaulon paschale Hoffm. podium obscurum L., Nepherite, Stachytarpheta jamaicensis Boenninghausenia sessilicarpa Levl., Ficus sarmentosa (L.) Vahl, Magnolia denudata desr. Zea mays L., Opuntia Buch-Ham. ex J. E. Sm. var. henryi (King) Corner, Sulphur, dillenii Haw, Pedilanthus tithymaloides (L.) Poit., Hosta Pilea plataniflora C. H. wright, Pelargonium hortorum plantaginea (Lam.) Aschers. Solanum pseudo-capsicum L., Bailey, Zacco platypus (Schl.), Punica granatum L., Pepero Mahonia bealei (Fort.) Carr., M. fortunei (Lindl.) Fedde, M. mia dindigulensis Miq., Sedum minginianum Fu, Sedum tet japonica (Thunb.) DC., Blumea balsamifera D.C., Artemisia ractinum Frd. Sinocrassula indica (Decne.) Berger, Juncus argvi Levl. et Vant. Artemisia vulgaris L., Artemisia tauricai, efuses L. var. decipiens Buchen. f. utilis Mak. Ranunculus Blumea balsamifera D.C., Benincasa hispida (Thunb.) Cogn. sceleratus L., Vaccinium saxicolumn Chun ex Sleumer, Pseu var. chichpua How, Alternanthera sessilis (L.) DC., Arcan dosciaena crocea (Rich.), P polyactis Bleeker, Lindera gelisia loureiri (Pier.) Diels, Streptocaulon griffithii Hook.f., setchuenensis Gamble, Acorus gramineus Soland. Vitex Cryptolepis buchanani Roem. et Schult. Cryptolepis san quinata (Lour.) F. N. williams, Uraria crimita DesV. Var. mac guinolenta Schlechter, Solanum nigrum L. var. pauciflorum rostachya wall. Olystichum braunii (Spenn.) Fe, P624-2, Liou, Montmorillonite, Fullers earth, Nardostachys chinen Cybister tripunctatus orientalis Gschew. P625, Gentiana sis Batal. Nardostachys jatamanse D.C., Clycyrrhiza uralen scabra Bge. Gentiana triflora Pall. Gentiana manshurica sis Fisch. Glycyrrhiza glabra L., Glycyrrhiza kansuensis Kitag., Gentiana rigescens Franch. G. rigescens Franch. var. Chang et Peng, Glycyrrhiza inflata Batal., Euphorbia kansui Stictantha Marquand, Gentianopsis paludosa (Munro) Ma, Liou, Euphorbia sieboldiana, E. sieboldiana Morr. et Decne. G. lutea L., Gipunctata L., Tubocapsicum anomalum (Franch. Brassica oleracea L. var. Capiata L., B. Oleracea L., Saccha et Sav.) Mak. Solanum nigrum L., Solanum auriculatum, S. US 2009/01 04295 A1 Apr. 23, 2009

xanthocarpum, Ottelia alismoides (L.) Pers. Cypripedium Mak. Ampelopsis meliaefolia, Cynanchum atratum Bge. henryi Rolfe, Sauropus rostratus Miq., Nupharbornetii Levl. Cynanchum versicolor Bge. Millettia bonatiana Pamp., et Vant., Physaliastrum heterophyllum (Hemsl.) Mak., Jun Passer montanus Saturatus Stejneger, Passer rutilans rutilians cus setchuensis Buchen. Var. effusoides Buchen., Poa (Temminck), Rhodiola henryi (Diels) Fu, Ledum palustre L. sphondylodes Trin. Gracilaria verrucosa (Huds.) Papenf. var. angustum E. Busch, Melaleuca leucadendra L., Serissa Physeter Catodon L., Tubocapsicum anomalum (Franch et serissoides (D.C.) Druce, Serissa foetida Comm., Tremella Sav.) Mak. Passiflora foetida L., Euphoria longan (Lour.) ficiformis Berk. Quercus acutissima Carr. O. aliena Bl. Stend. Ixora chinensis Lam., Solanum nigrum L., Agrimonia Inula Cappa D.C., Cucubalus baccifer L., Arnebia saxatilis pilosa Ledeb. Var. japonica (Miq.) Nakai, Sauropus rostratus Benth. et Hook. Solanum lyratum Thunb., Solanum dulca Miq., Dryobalanops aromatica Gaertn. f. Rubus sieboldi mara L., Delphinium pogonanthum Hand.-MaZZ., Quartz, Blume. Potamogeton pectinatus L., Anaphalis nepalensis P702, Lactuca indica L., Michelia alba D.C., Pulsatilla chin (Spr.) Hand-MaZZ., Porana racemosa Roxb., Anemone hupe ensis (Bge.) Reg., OykSatukka dagyrruca (Fisch.) Spr., Pul hensis Lem. Aster dubius (Thunb.) Onno, Aster scaber satilla koreana Nakai, Pulsatilla turczaminovii Krylov et Thunb., Scopolia japonica Maxim. Agriophyllum arenarium Serg., Pulsatilla ambigua Turcz. ex Pritz. Potentilla chinen Bieb., Aster scaber Thunb., Atalantia buxifolia (Poir.) Oliv., sis Ser. P. discolor Bge. Anemone vitifolia Buch-Ham..., A. woodwardia Orientalis Sm. Artemisia finita Kitag., Blech hupehensis Lem. A. tomentosa (Maxim.) Pei, Pulsatilla nig num Orientale L., Glehnia littoralis F. Schmidt ex Miq., ricans, Anemone Cernua, Pulsatilla nigricans, Paeonia lacti Nitraria Sibirica Pall. Ainsliaea pertyoides Franch. var. flora Pall. Populus davidiana Dode, Populus bonatii Levl. albotomentosa Beauverd, Helwingia japonica (Thunb.) Amomum cardamomum L., Elettaria cardamomum white et Dietr., Helwingia himalaica Clarke, Helwingia chinensis Maton, Angelica dahurica (Fisch. ex Hoffm.) Benth. et Batal. Bougainvillea glabra Choisy, Bougainvillea glabra Hook. f. ex Franch. et Sav., A. anomala Lallem. A. taiwani var. Sandericna, Euphorbia heterophylla L., Tilia tuan ana Boiss., Plumbago zeylanica L., Termstroemia gymnan SzySZ., Helwingia japonica (Thunb.) Dietr., H. himalaica thera (wight et Arm.) Sprague, Cleome gynandra L., Agki Clarke, H. Chinensis Batal., Pleonomus canaliculatus Falder strodon acutus (Ginther), Bungarus multicinctus Blyth, mann, Agriotes fiascicollis Miwa, Melanotus caudex Lewis. Elaphe moellendorffii (Boettger), Clematis maximowicziana Mecopoda elongata L., Philydrum lanuginosum Banks, Franch. Brassica alba (L.) Boiss., Perilla frutescens (L.) Cipangopaludina chinensis (Gray), Convolvulus arvensis L., Britt., Phaseolus vulgaris L., Saccharum Sinensis Roxb. Smithia sensitiva Ait., Turbo cornutus Solander, Arisaema Salvia scapiformis Hance, Pinus bungeana Zucc., Pinus mas ringens (Thunb.) Schott, Veronicastrum cauloptera (Hance) Soniana Lamb., Fraxinus malacophylla Hemsl., Sophora Yamazaki, Cissus pteroclada Hayata, Galium bungei Stend. viciifolia Hance, Imperata cylindrica (L.) P. Beauv. Var. Galium gracilens (A. Gray) Mak. Chloranthus henryi major (Nees) C. F. Hubb., Ginkgo biloba L., Acanthopanax Hemsl., Lysimachia paridiformis Franch. Lysimachia trien trifoliatus (L.) Merr., Parnassia foliosa Hook. ft. et Thoms. taloides Hemsl., Caesalpinia sepiaria Roxb., Anagallis var. nummularia Nakai, P. wightiana wall. Buddleia asiatica arvensis L., Japalura flaviceps Barbour et Dunn, Chloran Lour. Tilia Omeiensis Fang, Chelidonium maius L., Chelido thus multistachys Pei. Schnabelia Oligophylla Hand.-MaZZ. nium maius L. var. grandiflorum DC., P727, Coluber spinalis Liriodendron chinensis (Hemsl.) Sarg., Cucumis melo L. var. (Peters), Beesia calthaefolia (Maxim.) Ulbr., Quercus fabri flexuosus Naud., C. melo L. var. conomon Mak. Zingiber Hance, Fragaria nilgerrensis Schlocht. Stephania cepharan officinale Rosc. Rhus verniciflua. Stokcs, Stelmatocrypton tha Hayata, Dioscorea panthaica Prain et Burkill, Pteroxy Khasianum (Benth.) H. Baill. Twlorrhynchus heterochaeta gonum giraldi Dammer et Diels, Mallotus apelta (Lour.) Quatrefages, Eria graminifolia Lindl., Hematite, Curculigo Muell.-Arg. Lindera gambleana Allen, Populus alba L., orchioides Gaertn., Phyllostachys nigra (Lodd.) Munro var. Cynanchum bungei Decne. Cynanchum auriculatum Royle henonis (Mitf.) Stapfex Rendle, Pleioblastus amarus (Keng) ex wight, C. wilfordi (Maxim.) Hemsl., Betula pendula Roth, Kengf. Echinopsis multiplex Zucc., Opuntia dillenii Haw. Anas domestica L., Sesamum indicum D C., Liquidambar Opuntia monacantha Haw. P664, Scorzonera albicaulis taiwaniana Hance, Prunus mume (Sieb.) Sieb. et Zucc., Smi Bge. Pyrus hondoensis Nakai et Kikuchi, Opuntia dillenii lax lunglingensis wang et Tang, Asystasiella neesiana (wall.) Haw. Agrimonia pilosa Ledeb. Var. japonica (Miq.) Nakai, Lindau, Mussaenda parviflora Mig. Mussaenda divaricata Agrimonia pilosa Ledeb. Var. viscidula Kom., A. pilosa Hutch. Elaeagnus viridus Serv. Var. delavayi Lecte. Anser Ledeb. Var. nepalensis (D. Don) Nakai, A. pilosa Ledeb., A. domestica Geese, Canarium album (Lour.) Raeusch. Setaria pilosa Ledeb. Var. Coreana (Nakai) Liou et Cheng, A. pilosa italica (L.) Beauv., Ampelopsis japonica (Thunb.) Mak., Ledeb. f. davurica Nakai, A. asiatica JuZ., Agrimonia pilosa Fraxinus Chinensis Roxb., Dictamnus dasyCarpus Turcz. Ledeb. Var. japonica (Miq.) Nakai, Bletilla striata (Thunb.) Dictamnus angustifolius G. Don, D. albus var. Caucasicus, Reichb.f., Micromelum falcatum (Lour.) Tanaka, Atracty Bombyx mori L., Beauveria bassiana (Bals.) Vuill. Argyreia lodes macrocephala Koidz., Euonymus tengyuehensis W. W. acuta Lour., Argyreia liliflora C. Y. Wu, Dioscorea hispida Smith, Vigna cylindrica (L.) Skeels, Lactuca sativa L., Dennist. SymplocoSpaniculata (Thunb.) Miq., Rhodiola hen Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex rvi (Diels) Fu, Viola arcuata Bl, Melaleuca leucadendra L., Franch. et Sav., Angelica anomala Lalem. Angelica taiwa Equus cabalus (L.), Serissa serissoides (D.C.) Druce, S. niana Boiss., Heracleum scabridum Franch. Amaranthus foetida Comm., Heracleum rapula Franch. Solanum lyratum viridis L., Brassica alba (L.) Boiss., Alunite, Ginkgo biloba Thunb., Punica granatum L. var. albescens D C., Punica L., Erythroculterilishaeformis (Bleeker), Chalk, P686, Cyn granatum L. Var. multiplex Sw., Senecio magensium C. B. anchum Stauntoni (Decne.) Schltr. ex Levl., Cynanchum Clarke, Elaeagnus Oldhami Maxim. Pulsatilla chinensis glaucescens (Decne.) Hand.-MaZZ., Prunus mume (Sieb.) (Bge.) Reg., Gerbera delavayi Franch. Populus davidiana Sieb. et Zucc., Acorus calamus L., Acorus calamus L. Var. Dode. Amomum cardamomum L., Styrax dasyantha Perk. angustatus, Lophura nycthemera nycthemera (L.), Artemisia Gentiana algida Pall. G. algida Pall. Var. przewalski sieversiana Ehrh. ex willd.; Ampelopsis japonica (Thunb.) (Maxim.) Kusnez., Iris dichotoma Pall. Cleome gynandra L., US 2009/01 04295 A1 Apr. 23, 2009

Agkistrodon acutus (Gwnther), Fluggea virosa (wild.) Baill. Link, S. grandiflora (Maxim.) Mak. S. longifolia Bertol., Isodon sculponieatus (Vant.) Kudo, Paederia scandens Parthenocissus tricuspidata (Sieb. et Zucc.) Planch. (Lour.) Merr. var. tomentosa (Bl.) Hand.-Mazz., Sophora Astragalus bhotanensis Bak. Stephania delavayl Diels, viciifolia Hance, Ginkgo biloba L., Aristolochia championii Lithospermum Zollingeri DC., Lithospermum arvense L., Merr. et Chun, Buddleia asiatica Lour. Chelidonium maius Viola diffiusa Ging. Pachyrhizus erosus (L.) Urban, Ficus L., Gynura divaricata (L.) DC., Mallotus apelta (Lour.) tikoua Bur., Ruellia drymophila (Deils) Hand-Mazz., Hyperi Muell.-Arg., Nelumbo nucifera Gaertn., Chrysanthemum cum japonicum Thunb., Kadsura heteroclita (Roxb.) Craib, morifolium Ramat., Fraxinus chinensis Roxb., Rhinacanthus Lotus corniculatus L., Luzula capitata (Miq.) Miq., L. mul nasuta (L.) Kurz, Argyreia acuta Lour., Bellamya quadrata tiflora (Ehrh.) Lei. Polygala crotalarioides Buch-Ham.. (Benson), Ajuga decumbens Thunb., Pulsatilla chinensis Abacopteris penangiana (Hook.) Ching, Pratia begonifolia (Bge.) Reg., Populus davidiana Dode, Rhododendron mucr (wall.) Lindl., Kochia scoparia (L.) Schrad. Kochia scoparia Onatum G. Don, Dracocephalum heterophyllum Benth. (L.) Schrad. f. trichophila Schinz et Thell. K. sieversiana Agkistrodon acutus (Gwnther), Oldenlandia diffusa (wild.) (Pall.) C. A. Mey. Chenopodium album L., Asplenium Roxb., Oldenlandia corymbosa L., O. tenellifora (Bl.) O. incisum Thunb., Selaginella moellendorfii Hieron. Viola Ktze., O. pinifolia (wall.) K. Schum. Sophora glauca Lesch. philippica Cav. Subsp. malesica W. Beck. Lycium chinense var. albescens Rehd. et wils. Gynura divaricata (L.) DC., Mill. Myrmeleon micans Mac Lachlan, Drosera spathulata Cucumis melo L., Polygala japonica Houtt. Fissistigma Old Labill., Urena lobata L., Viola collina Bess., Rubus xantho hamii (Hemsl.) Merr, Polygonum caespitosum Bl. Ficus carpus Bur. et Franch. Veronica serpyllifolia L., Cynanchum comata Hand.-MaZZ., Ficus religiosa L., Benincasa hispida thesioides (Freyn) K. Schum. Marchantia polymorpha L., (Thunb.) Cogn. Debregeasia edulis (Sieb. et Zucc.) wedd. Melastoma dodecandrum tour., Rehmannia glutinosa Ilex chinensis Sims, Malva verticillata L., Abutilon theo (Gaertn.) Libosch. Viola grypoceras A. Gray, Munronia hen phrasti Medic. Malva verticillata L., Hepialus armoricanus rvi Harms, Rehmannia glutinosa (Gaertn.) Libosch. Mollugo Oberthwr, Cordyceps sinensis (Berk.) Sacc., Kalopanax sep pentaphylla L., Euphorbia humifiusa wild. Euphorbia pilu temlobus (Thunb.) Koidz., Aralia chinensis L., P769, Scro lifera, Chamaerhodos erecta (L.) Bge. Raphanus sativus L., phularia ningpoensis Hemsl., S. grossheimi, S. nodosa, P771, Snaphalium adnatum wall. ex DC., Stellaria saxatilis Buch.- P772, Lancea tibetica Hook.f. et Thoms., wahlenbergia mar Ham. Rubus iremaeus Focke, Ficus tikoua Bur., Kadsura ginata (Thunb.) A. D.C., Caryopteris incana (Thunb.) Miq., heteroclita (Roxb.) Craib, Cotoneaster horizontalis Decne. Lancea thibetica Hook.f. et Thoms. Cypripedium margari var. perpusilla Schneid. Ophiorrhiza succirubra King eX taceum Franch. Pinelia ternate (Thunb.) Breit., Pinellia Hook.f., Musela lasiocarpa (Franch.) C.Y. wu, P831, Abies pedatisecta Schott, Portulaca grandiflora Hook. Elsholtzia Sutchuenensis (Franch.) Rehd. et wils. Celtis sinensis Pers. ciliata (Thunb.) Hyland, Lobelia chinensis Lour., Christia Colocasia esculenta (L.) Schott, Trillium tschonoskii Obcordata (Poir.) Bahn. f... Pteris semipinnata L., Scutellaria Maxim. Trillium camtschaticum Pall. Achnatherum splen barbata D. Don, Perularia ussuriensis (Reg.) Schltr., P784, dens (Trin.) Nevski, Miscanthus sinensis Anderss., Mirabi Passiflora wilsonii Hemsl., Pterospermum heterophyllum lite, Hypericum patulum thunb., Dicranopteris dichotoma Hance, Semiliquidambar cathayensis H. Y. Chang, Dendro (Thunb.) Bernh., Euphrasia maximowiczii wettst. Sesamum panax proteus (Champ.) Benth., Sassafras tsumu Hemsl., indicum DC., Reineckea Carnea Kunth, Lobaria pulmonaria Artocarpus hypargyraea Hance, Alectoria asiatica Du Rietz, (L.) Hoffm., Bauhinia variegata L., Leontopodium leontop Deutzia ningpoensis Rehd., Glycyrrhiza pallidiflora Maxim. dioides (wils.) Beauv. Cynanchum inamoenum (Maxim.) Ficus taiwanicola Maxim. Var. angustifolia (Cheng) Migo, Loes., Rubus pinfaensis Levl. et Vant. Polygonatum cirrhi Ficus heteromorpha Hemsl., Crepis phoenix Dunn, Cudrania folium (wall.) Royle, Diospyros rhombifolia Hemsl., Calli cochinchinensis (Lour.) Kudo et Masam., Sapindus delavayi carpa bodinieri Levl. var. giraldii (Rehd.) Rehd., Thladian (Franch.) Radlk. Vernonia andersonii Clarke, Pteracanthus tha verrucosa Cogn. ex Oliv., Medicago lupulina L., alatus (wall. et Nees) Brem. Cassia alata L., Ceropegia Capparis spinosa L., Berchemia lineata (L.) DC., Ilex pernyi pubescens wall. Cynanchum hancockianum (Maxim.) Al. Franch. Acanthus ilicifolius L., Erodium Stephanianum Iljinski, Satyrium nepalense D. Don, Passiflora cupiformis willd. Geranium wilfordii Maxim. Geranium nepalense Mast. Polystichum tsus-simense (Hook.) J. Sm., Callicarpa Sweet, Geranium Sibiricum L., Geranium Carolinianum L., rubella Lindl., Viburnum ichangensis Rehd., Chloranthus G. dahuricum D.C., G. dahuricum D C. var. alpinum Bar. et serratus (Thunb.) Roem. et Schult., Nanocnide japonica B1. SkV., Amaranthus caudatus L., Mucuna wangii Hu, Mucuna Quercus liaotungensis Koidz., Lutfa cylindrica (L.) Roem. macrocarpa wall. Brucea javanica (L.) Merr., Sabia yunnan Lufa acutangula roxb., P792, Drymotaenium miyoshianum ensis Franch. Epalites australis Less. Bauhinia variegata L., (Mak.) Mak., Euonymus bungeanus Maxim. Lindernia crus Phryma leptostachya L., Citrullus vulgaris Schrad., P850, tacea (L.) F. Mucl., Matricaria chamomilla L., Syzygium Mactra antiquata Spengler, Panax quinque folium L., Passi aromaticum (L.) Merr. et Perry, Cayratia carnosa Gagn. flora caerulea L., Nasturtium officinale R.Br., Linum usitatis Arisaema purpureo-galeatum Engl., Halite, Viola yedoensis Simum L., Oryza sativa L., Oroburea (L.) Pers. Chenopodium Mak. Viola japonica Langsd., Gueldenstaedtia multiflora serotinum L., Polystichum deltodon (Bak.) Diels, Cotoneas Bge. Gueldenstaedtia pauciflora (Pall.) Fisch. Gentiana ter acutifolius Turcz., Lilium brownii F. E. Browm var. loureiri (D. Don) Griseb., Viola inconspicua Bl. V patrinii D colchesteri wils. Lilium pumilum D.C., Lilium longiflorum C. V. Oxycentra JuZ., Corydalis bungeana Turcz., Anemone Thunb., Lilium dahuricum Ker-Gawl., L. Concolor Salisb., L. flaccida Fr. Schmidt, Pachyrhizus erosus (L.) Urban, Bur Cernuum Kom., L. concolor Salisb. Var. buschianum Bak. L. mannia coelestis D. Don, Melo coarctatus Motsch. Lycopus distichum Nakai, L. davidii Duch., L. martagon L., Stemona lucidus Turcz., P803, Melastoma dodecandrum Lour., Thy japonica (Bl.) Miq., Stemona sessilifolia (Miq.) Franch. et mus serpyllum L., Thymus mongolicus Ronn., Heteropogon Sav. Stemona tuberosa Lour. Stemona parviflora Wright, S. contortus (L.) Beauv. Sanguisorba officinalis L., San vagula W. W. Smith. Asparagus filicinus Ham. ex D. Don, A. guisorba parviflora (Maxim.) Takeda, S. tenuifolia Fisch. et officinalis L., Turdus merula mandarinus Bonaparte, Ardisia US 2009/01 04295 A1 Apr. 23, 2009

crispa (Thunb.) A. D.C., Aridisia brevicaulis Diels, Marsde laris Kuang, Impatiens chinensis L., Combreturn alfredii nia longipes W. T. Wang, Disporum sessile (Thunb.) D. Don Hance, Chrysosplenium sinicum Maxim. Corydalis van var. flavens (Kitag.) Y. C. Tang, Disporum cantoniense husuo W.T. Wang, Corydalis ambigua Cham. Et Schlecht. Var. (Lour.) Merr., Aletris lanuginosa Bur. et Franch., P864, P865, amurensis Maxim. C. ambigua Cham. et Schlecht., C. Lotus corniculatus L., Morinda parvifolia Bartl. Thesium remota Fisch. ex Maxim. Corydalis hamosa Migo, Corydalis chinense Turcz., Ardisia crispa (Thunb.) A. D.C., Gymnoth remota Fisch var. lineariloba Maxim, Corydalis remota Fisch eca chinensis Decne. Neottianthe cucullata (L.) Schltr., var. pectinata Kom, Ranunculus cantoniensis D.C., Crota Nerium indicum Mill. Cyclemy's sp., Cyclemy's trifasciata laria assamica Benth., Pyrite, P925, wedelia wallichii Less. Bell, Polygonum perfoliatum L., Cynanchum officinale Taxus mairei (Lemee et Levi.) S.Y. Hu, Daemonorops draco (Hemsl.) Tsiang et Zhang, Seseliseseloides (Fisch. et Mey. ex B1. Pleomele Cambodiana (Pier. ex Gagn.) Merr. et Chun, Turcz.) Hiroe, Ampelopsis aconitifolia Bge. Reinwardtia tri Schisandra henryi Clarke, Schisandra sphenanthera Rehd. et gyna (Roxb.) Planch. Lycopodium complanatum L., Lycopo wils., Lespedeza buergeri Miq., Chenopodium hybridum L., dium casuarinoides Spring, Adiantum flabellulatum L., Jus Ventilago leiocarpa Benth., Sambucus adnata wall. Galin siaea repens L., Embelia pauciflora var. blinii (Levl.) walker, Soga parviflora Cav., Sesbania cannabina (Retz.) Pers. Bauhinia championi (Benth.) Benth., Callicarpa longissima Helianthus annuus L., Pheropsophus jessoensis Mor. Buthus (Hemsl.) Merr., Cyrtomium caryotideum (wall.) Presl, martensi Karsch, Androctonus australis, Dracocephalum Angelica sinensis (Oliv.) Diels, Angelica acutiloba (Sieb. et integrifolium Bge., Rubus amphidasys Focke, Aeschy Zucc.) Kitag. Ligusticum glaucescens Franch. Levisticum momene indica L., Actinostemma lobatum (Maxim.) Maxim. officinale Koch, Angelica acutiloba var. Sugiyama Hikino, Albizzia julibrissin Durazz., Albizzia chinensis, Albizzia Embelia parviflora wall. Pyrrosia clavata (Bak.) Ching, Kalkora (Roxb.) Prain, A. gummifera, Albizzia julibrissin P880, Tulipaedulis Bak. Tulipailiensis Reg., Croton laeviga DuraZZ., Aeschynomene indica L., Polygala lateriflora Y. K. tus Vahl, Stachyspalustris L., Trema cannabina Lour. Sedum Yang et al., Cynanchum amplexicaule Hemsl., Polygonum dry marioides Hance, Bullacta exarata (Philippi), Pellionia polystachyun wall. Zanthoxylum multijugum Franch. Bal repens (lour.) Merr., Strychnos ignati Berg., Mallotus phil anophora polyandra Griff. Clinopodium polycephalum ippinensis (Lam.) Muell.-Arg., Celastrus angulata Maxim. (Van.) C. Y. Wu et Hsuan, Dysosma auranticocaulis (Hand.- Viburnum cylindricum Buch.-Ham. ex D. Don, Zebrina pen MaZZ.) Hu, Melastoma polyanthum Bl. Meconopsis hor dulla Schnizl., Ceropegia christenseniana Hand.-MaZZ. ridula Hook. f. et Thoms., Vicia multicaulis Ledeb., Litho Rubus innominatus S. Moore var. Kuntzeanus (Hemsl.) carpus polystachyius Rehd., Alnus tinctoria Sarg., Anas Bailey, Rhodobryum roseum Limpr., Cicer arietinum L., platyrhynchos L., Artemisia anomala S. Moore, Siphonoste Ranunculus chinensis Bge. Atylosia mollis (wild.) Benth. gia chinensis Benth. Artemisia selengensis Turcz., Lepisma Sanguisorba filiformis (Hook. f.) Hand.-Mazz., Phyl saccharina L., Equisetum arvense L., Arctia Caja L., Juncus lostachys nigra (todd.) Munro var. henonis (Mitf.) Stapf ex efusus L. var. decipiens Buchen. Juncus leschenaulti Gay. Rendle, Isodon termifolius (D. Don) Kudo, Fraxinus chinen J. Setchuensis Buchen. Var effusoides Buchen. Ribes mand sis Roxb., Ligustrum lucidum Ait., Exicerus pela (Cha Schuricum (Maxim.) Kom. Physalis peruviana L., Juncus Vannes), Cinnamomum cassia Presl, Myristica fragrams efusus L. var. decipiens Buchen., Erigeron breviscapus Houtt., Cistanche salsa (C. A. Mey.) G. Beck, Cistanche (Vant.) Hand.-MaZZ. Erigeron bonariensis, Cassia tora L., ambigua (Bge.) G. Beck, Impatiens microcentra Hand.- P951, Dryobalanops aromatica Gaertn. f. Blumea balsam MaZZ., Cinnamomum cassia Presl, Myristica fragrams Houtt. ifera D.C., P953, Aneurolepidium dasystachys (Trin.) Nevski, Phyllostachys migra (Lodd.) Munro var. henonis (Mitf.) Stapf Pinna pectinata L., Hydrocotyle Sibthorpioides Lam. Var. ex Rendle, Phyllostachys sulphurea (Carr.) A. et C. Riv., batrachium (Hance) Hand.-Mazz., Hydrocotyle Sibthorpio Bambusicola thoraica thoraciac (Temm.). Labeo decorus ides Lam., Stephania hermandifolia walp., Campylotropis Peters, P900, Bambusa textiles McClure, Shiraia bambusi macrocarpa (Bge.) Rehd., Styrax benzoin Dryand. Styrax cola Henn., Xvlocopa dissimilis (Lep.), P903, Tupistra ensi tonkinensis (Pier.) Craib, Styrax hypoglauca Perk. S. mac folia wanget Tang, Commelina diffusa Burm. f. Homalocla rothyrsus Perk. S. subnivea Merr. et Chun, Aristolochia man dium platycladium (F. Muell.) Bailey, Murdannia divergens Shuriensis Kom. Aconitum Coreanum (Levl.) Raipaics, (C. B. Clarke) Brcckn. Disporum cantoniense (Lour.) Merr., Capra hircus L., Ovis aries L., Rumex japonicus Houtt. Polia japonica Thunb., Commelina benghalensis L., Zan Rumex nepalensiSpr., Rumex confertus wild. Rumex japoni thoxylum planispinum Sieb. et Zucc., Conax Cannaeformis cus Houtt. Rumex nepalensis Spr., Zanthoxylum dimorpho (Forst.) Schum. Tecomaria capensis (Thunb.) Spach, Strep phyllum Hemsl., Liparis japonica (Miq.) Maxim. Strophan topus simplex D. Don, Lingnania chungi McClure, Sinocala thus divaricatus (Lour.) Hook. et Arm. Polygonatum mus affinis (Rendle) McClure, Tupistra chinensis Bak. Rhi verticillatum (L.) All. Polygonatum roseum (Ledeb.) Kunth, zomys sinensis Gray, Lyctus brunneus Steph., Panax pseudo Lindernia angustifolia (Benth.) wettst. Morinda umbellata ginseng wall. Var. japonicus (C. A. Mey.) Hoo & Tseng, L., Osmanthus matsumuranus Hayata, Rumex japonicus Panax pseudo-ginseng wall. Var. bipinnatifidus (Seem.) Li, P Houtt., R. nepalensis Spr., Emilia sonchifolia (L.) DC., pseudo-ginseng wall. Var. angustifolius (Burkill) Li, Laggera alata (Buch.-Ham.) Sch.-Bip., Buddleia officinalis Anemone raddeana Reg., Lathyrus palustris L. var. lineari Maxim. Strophanthus divaricantus (Lour.) Hook. et Arm. folius Ser. Lathyrus sativus, Seseli mairei Wolff, Seseli yun Carex lanceolata Boott, Viburnum utile Hemsl., Rhododen manense Franch. Zanthoxylum planispinum Sieb. et Zucc., dron mole (Bl.) G. Don, Passiflora altebilobata Hemsl., Rhizomys sinensis Gray, Lyctus brunneus Steph., Claoxylon P973, P974, Aglaia odorata Lour., Oryza sativa L., P975, polot (Burm. f.) Merr., Erythrina arborescens Roxb., Calli Eurya chinensis R. Br. Vaccinium sprengelii (C. Don) carpa arborea Roxb., Cinnabar, Salvia cavaleriei Levl. Ardi Sleumer, Erigeron Canadensis L., Allophylus viridis radlk. sia crenata Sims, Aristolochia kaempferi willd. Damnacan Cyperus diformis L., Aristolochia mollissima Hance, Aver thus indicus Gaertn. f., P915, Vernonia cinerea (L.) Less. rhoa carambola L., Actinolite, Actinolite asbestus, Actinoli Symplocos chinensis (Lour.) Druce, Physochlaina infundibu tum brevi?ibrium, Caragana franchetiana Kom. Platysternon US 2009/01 04295 A1 Apr. 23, 2009 megacephalum Gray, Botrychium ternatum (Thunb.) Sw., microcephala Ce-3, Bulbophyllum inconspicuum Maxim. Cinnamomum burmannii (Nees) Bl. Stephania tetrandra S. Ophiopogon japonicus Ker-Gawl. Ophiopogon intermedius Moore, Aristolochiafangchi wu, Cocculus trilobus (Thunb.) D. Don, Liriope spicata Lour., L. minor (Maxim.) Mak. L. D.C., Aristolochia heterophylla Hemsl., Sinomenium acutum kansuensis (Batal.) C. H. Wright, Ophiopogon japonicus Ker (Thunb.) Rehd. et wils. Menispermum dauricum DC., Aris Gawl. Var. genuinus Maxim. Silene Conoidea L., Boehmeria tolochia moupinensis Franch. A. kaempferi willd. Saposh gracilis C. H. Wright, Dalbergia minosoides Franch. Map nikovia divaricata (Turcz.) Schischk. Ligusticum brachy pianthus iodoides Hand.-MaZZ., Polygala tenuifolia willd. lobum Franch. Seseli mairei wolff, Seseli yunnanense Indigofera neopolygaloides Hu, Phlomis tuberosa L., Ouer Franch. Seseli iliense (Reg. Et Sclmalh.) Lipsky, Saposhni cus liaotungensis Koidz. Mallotus repandus (wild.) Muell.- kovia divaricala (Turcz.) Schischk. Anisomeles indica (L.) Arg., Eucommia ulmoides Oliv., Cuculus poliocephalus O. Ktze. Gynura bicolor D. C., Microsorium dilatatum Latham, Asarum forbesii Maxim. Juniperus rigida Sieb. et (Bedd.) Sledge, Syringa pinnatifolia Hemsl., Panax pseudo Zucc., Maesa japonica (Thunb.) Moritzi, Rhododendron sim ginseng wall. Var. bipinnatifidus (Seem.) Li, Gnetum parvi sii Planch. Cunninghamia lanceolata (Lamb.) Hook. Hip folium (warb.) C. Y. Cheng, Styrax suberifolia Hook. et Arn. puris vulgaris L., Mangifera indica L., Myrica rubra Sieb. et Remusatia vivipara (lodd.) Schott. Monascus purpureus Zucc., weigela japonica Thunb. Myrica esculenta Buch.- went, Ormosia hosiei Hemsl. et wils., Carthamus tinctorius Ham... Myrica rubra Sieb. et Zucc., Glycine max (L.) Merr., L., Arisaema balansae Engl. Solanum Septemlobum Bge. Campylotropis delavayi (Franch.) Schindl., Iris sanguinea Polygonum Sufiultum Maxim. Desmodium Szechuenense Hornem. Litsea cubeba (Lour.) Pers., L. pungens Hemsl., L. (Craib) Schindl., Orchis salina Turcz., Pyracantha fortu euosma W. W. Smith, Amomum cardamomum L., Peperonia neana (Maxim.) Li, Begonia fimbristipulata Hance, Begonia reflexia (L. f.) A. Dietr., P1045-1046, Helicia erratica Hook. membranifera Chun et F. Chun, Carrierea calycina Franch. f, Papaver rhoeas L., Polycarpaea corymbosa (L.) Lam., Iresine herbstii Hook. f. Kadsura longipedunculata Finet et Crossostephium chinense (L.) Mak. ex Cham. et Schltr., Gagn. Tetrastigma Obovatum (Laws.) Gagn. Leontice robus Daphne genkwa Sieb. et Zucc., wikstroemia chamaedaphne tum (Maxim.) Diels, Centropus sinensis (Stephens), C. ben Meissn., Ulmus macrocarpa Hance, Brassica rapa L., Bras galensis (Smelin), Murdannia malabaricum (L.) Brckn. sica campestris L. var. Oleifera D.C., Cymbopogon distans Eupatorium heterophyllum DC., Umbilicaria hypococcina (Nees) A. Camus, Sonchus brachyotus D. C., Amaranthus (Jatta) Llano, Gyrophora tornata Ach. Dermatocarpon min mangostanus L., Percocypris pingi (Tchang), Polemonium iatum (L.) Mann., Blumea lacera (Burm. f.) DC., Peristrophe liniflorum V. Vassil. Polemonium coeruleum L., Zanthoxy roxburghiana (Schult.) Brem. Larix potaninii Batal. Alpinia lum bungeanum Maxim. Zanthoxylum schinifolium Sieb. et galanga (L.) Swartz, Carthamus tinctorius L., Astragalus Zucc., Zanthoxylum simulans Hance, Z. planispinum Sieb. et sinicus L., Hypericum ascyron L., Actinodaphne cupularis Zucc., Z. avicennac (Lam.) DC., Z. simulans Hance var. (Hemsl.) Gamble, Strobilanthes japonicus (Thunb.) Mid. podocarpum (Hemsl.) Huang, Z. piperitum D C., Sorbus Laportea macrostachya (Maxim.) Ohwi, Polygonum ciliin pohuashanensis (Hance) Hedl., Halenia corniculata (L.) erve (Nakai) Ohwi, Alchornea trewioides (Benth.) Muell.- CornaZ., Clematis pseudopogonandra Finet et Gagn. Malus Arg., Salvia plectranthoides Griff, Anneslea fragrams wall. asiatica Nakai, Trigonella ruthenica L., Paederus densipen Dalbergia hancei Benth. Begonia laciniata Roxb., Huechy's nis Bernh. Lysimachia lobelioides wall. Cissus discolor Bi. sanguinea DeGeer. Rhus punjabensis Stew. Var. Sinica (Di Zanthoxylum bungeanum Maxim. Zanthoxylum schinifolium els) Rehd. et wils. Smilax glabra RobX., S. glauco-china Sieb. et Zucc., Begonia cathayana Hemsl., Ophicalcite, Pott warb., Smilax mairei Levl. Rubus rufo-lanatus H. T. Chang, sia laxiflora (Bl.) O. Ktze. Asarum maximum Hemsl., Ulmus pumila L. var. pilosa Rehd., Callicarpa rubella Lindl., Polygonum runcinatum Buch-Ham..., P. runcinatum Buch Mallotus barbatus (wall.) Muell-arg., Rhodiola sacra (Prain Ham. Var. Sinense Hemsl., Dryopteris laeta (Kom.) C. Chr. ex Hamet) Fu, Machilus thunbergii Sieb. et Zucc., Aralia Barleria lupulina Lindl., Barleria prionitis L., Munronia echinocaulis Hand.-MaZZ., Cyathocline purpurea (Ham.) O. sinica Diels, Oenanthe javanica (Bl.) DC., Brassica juncea Ktze. Chamaenerion angustifolium (L.) Scop., Polygonum (L.) Czern. et Coss., Atractylodes lancea (Thunb.) DC., flaccidum Meissn., Polygonum blunei Meissn., Persicaria Atractylodes chinensis Koidz., Atractylodes japonica Koidz. longiseta, Desmodium Szechuenense (Craib) Schindl., ex Kitam. A. Chinensis Koidz. var. Simplicifolia Kitag., A. Oxyria sinensis Hemsl., Hydrocotyle nepalensis Hook. Tri chinensis var. quinqueloba, A. chinensis var. liaotungensis, folium pratense L., Eupatorium heterophyllum DC. Alter Xanthium sibiricum Patr. ex widd., Indigofera hancockii nanthera versicolor Reg., Begonia crassirostris Irmsch. Craib, Saxiglossum angustissimum (Gies.) Ching, Diplocli Blumea mollis (D. Don) Merr., Viburnum ovatifolium Rehd., sia glaucescens (Bl.) Diels, Euryale ferox Salisb., Phragmites Desmodium gangeticum (L.) DC., Rhododendron arboreum communis Trin. Aloe vera L., Aloe ferox Mill. Aloe vera L. Smith f. roseum Sweet, R. campy locarpum Hook.f., Clematis var. Chinensis (Haw.) Berger, Piper boehmeriaefolium wall. brevicaudata D.C., Elaeagnus henryl warb., Swertia eryth Arundo donax L., Ruellia repens L., Musa basjoo Sieb. et rosticta Maxim. Ipomoea batatas Lam., Ilex sp., Illicium Zucc., Caesalpinia Sappan L., Perilla frutescens (L.) Britt. lanceolatum A. C. Smith, Ecdysanthera rosea Hook. et Arm. Var. Crispa (Thunb.) Hand.-Mazz., P. frutescens (L.) Britt. Rubus mallodes Focke, Begonia sinensis A. D.C., Castanop Var. acuta (Thunb.) Kudo, P. frutescens (L.) Britt., Indiogof sis hickelii A. Camus, Erigeron elongatus Ledeb. Alstonia era carlesii Carib, Liquidambar Orientalis Mill. Malva yunnanensis Diels, Acanthopanax giraldi Harms, Ardisia neglecta wallr. Blumea laciniata (Roxb.) DC., Ardisia manillata Hance, Meconopsis punicea Maxim. Caragana gigantifolia Stapft, Viola acuminata Ledeb., Tetrastigma rosea Turcz., Chamaenerion angustifolium (L.) Scop., obtectum (wall.) Planch. Salvia substolonifera Stilb., Pel Veronica ciliata Fisch. Agate, Ustilago nuda (Jens.) Rostr., lionia radicans (Sieb. et Zucc.) wedd. Alnus japonica Sieb. et Ustilago hordei (Pers.) Lagerh., Hordeum dislichon, Clavi Zucc., Thladiantha dubia Bge., Syzygium buxifolium Hook. ceps purpurea (Fr.) Tulasne, Secale cereale L., Claviceps et Arn., Phaseolus calcaratus Roxb., Phaseolus angularis microcephala Tulasne, C. purpurea (Fr.) Tulasne, Claviceps wight, Halloysite, Geranium strictipes R. Kunth, Paeonia US 2009/01 04295 A1 Apr. 23, 2009

lactiflora Pall. Paeonia obovata Maxim. Paeonia veitchii tata Hook. f. Incarvillea sinensis Lam., Incarvillea young Lynch, Paeonia anomala L., P mairel Levl., P. Obovata husbandii Sprague, Hypecoum erectum L., Chinemy's reevesii Maxim. Var. willmottiae (Stapf) Stern, P hybrida Pall. Pyra (Gray), Rhododendron mucronulatum Turcz., Jasminum cantha fortuneana (Maxim.) Li, Saccharum sinensis Roxb. nudiflorum Lindl., Magnolia liliflora DeSr., Magnolia denu Poria cocos (Schw.) wolf, Polygonum runcinatum Buch data DeSr., Magnolia fargesii Cheng, M. Campbellii Hook.f. Ham. Polygonum runcinatum Buch.-Ham. Var. Sinense et Thoms. Rubus Sachalinensis Levl., Viola dissecta Ledeb., Hemsl., Vespa simillima Smith. Dinodon rufozonatum (Can Machilus yunnanensis Lec. Var. duclouxii Lec. Rhamnus glo tor), Elatostema umbellatum Bl. Var. majus Maxim. Calys bosus Bge., Saruma henryi Oliv., Abies delavayi Franch. tegia Soldanella R.Br. Prunus armeniaca L., Parmeniaca L. Viburnum foetidum wall. Viola serpens wall. Pugionium var. ansu Maxim. Prunus Sibirica L., P. mandshurica Koe cornutum (L.) Gaertn., Elaeagnus angustifolia L., Salix hne, Pimpinella candoleana wight et Arm. Pimpinella cheilophila Schneid. Ammopiptanthus mongolicus (Maxim.) anisum, Prunus Salicina Lindl., Maesa indica wall. Cheng f. Astragalus complanatus R. Br., Astragalus chinen Polygonum amphibium L., Crepis elongata babc., Rhodiola sis L., Astragalus adsurgens Pall., Calligonum mongolicum yunnanensis (Franch.) Fu, Delphinium anthriscifolium Turcz., Ferula borealis Kuan, Oxytropis psammocharis Hance, Sedum verticillatum L., Pedicularis rex C. B. Clarke Hance, Acronychia pedunculata (L.) Mig. Artemisia halo ex Maxim., Euonymus fortunei (Turcz.) Hand.-Mazz., Hibis dendron Turcz., Echinops gmelinii Turcz. Oldenlandia capi cus rosa-simensis L., Amelanchier sinica (Schneid.) Chun, tellata (wall.) O. Ktze., Ferula borealis Kuan, Inula Salso Amelanchierasiatica Engl., Cyperus michelianus (L.) Link, loides (Trucz.) Ostenf. Commiphora myrrha Engl. Corydalis suaveolens Hance, Heterocodon brevipes (Hemsl.) Balsamodendron ehrenbergianum Berg., Ouercus infectoria Hand.-MaZZ. et Nannf., Jasminum amplexicaule Buch.- Olivier, Cynips gallae-tinctoriae Olivier, Aquilaria agal Ham..., Oxalis stricta L., Primula vittata Bur. et Franch., P. locha Roxb., Aquilaria sinensis (Lour.) Gilg. P1 172, Sikkimensis Hook. Forsythia suspense (Thunb.) Vahl, For Notopterygium incisum Ting, Notopterygium forbesii Boiss., Sythia koreana, F intermedia, Cercidiphyllum japonicum Notopterygium franchetii Boiss., Batrachuperus pinchonii Sieb. et Zucc. var. Sinense Rehd. et wils., P1114, wedelia (David), Terminalia chebula Retz., Terminalia chebula Retz. prostrata (Hook. et Arm.) Hemsl., W. prostrata (Hook. et var. gangetica Roxb., Limonium gmelinii (wild.) O. Ktze. Arm.) Hemsl. Var. robusta Mak. Salomonia cantoniensis Psoralea corylifolia L., Nothopanax delavayi (Franch.) Lour. Kadsura Oblongifolia Merr., Spiraea japonica L.f. Var. Harms, Channa asiaticus (L.), Ganoderma japonicum (Fr.) acuminata Franch. Evodia rutaecarpa (JuSS.) Benth. Evodia Lloyd, Ganoderma lucidum (Ley.S.S. ex Fr.) Karst. Meliosma rutaecarpa (Juss.) Benth. var. officinalis (Dode) Huang, E. cuneifolia Franch., Viverra zibetha L., Viverricula indica rutaecarpa (Juss.) Benth. var. bodinieri (Dode) Huang, Evo Desmarest, Swainsonia salsula Taub. Pithecellobium luci dia xanthoxyloides F. Muell. E. xanthoxyloides, Baeckea dum Benth., Pithecellobium saman, Pithecellobine, Diospy frutescens L, Ilex aspirella (Hook. et Arn.) Champ. ex Benth. ros lotus L., Sambucus javanica Reinw. Equus asinus L., Apium graveolens L. var. dulce D.C., Salix matsudana Koidz. Ferula assafoetida L., Ferula caspica Marsh.-Bieb., Ferula Tropaeolum majus L., Zephyranthes grandiflora Lindl., conocaula Eug., Fomes officinalis (Vill. et Fr.) Ames, Alyxia Ostrea rivularis Gould, Ostrea gigas Thunb., Ostrea talien Sinensis Champ. ex Benth. Trachyspermum ammi (L.) Spra whanensis Crosse, Artemisia japonica Thunb., A. japonica gue, Heteropappus altaicus (wild.) Novopokr. 21189, Thunb. f. resedifolia Takeda, Paeonia suffruticosa Andr. P1190, Lagenaria Siceraria (Molina) Standl. var. depressa Paeonia suffruticosa Andr. var. spontanea Rehd., P. papay Ser. L. Siceraria (Molina) Standl. Var. gourda Ser. Aconitum eracea Andr., P. lutea Franch., P. delavayi Franch. P. pota carmichaeli DebX., Trigonotis peduncularis (Trev.) Benth. nini Kom. P. Szechuanica Fang, P thalictrumifolia C. Ho etS. Millingtonia hortensis L.f., Lonicera japonica Thunb., Gal Y. Chen, P. lutea Franch., P. yunnanensis Fang, Paeonia lus gallus domesticus Brisson, Collybia albuminosa (Berk.) emodi, P. officinalis, Clematis heracleifolia D. C., Vitex Petch, Rhodotypos scandens (Thunb.) Mak., Jurinea non negundo L. var. cannabifolia (Sieb. et Zucc.) Hand.-MaZZ. golica Maxim. Randia sinensis (Lour.) Roem. et Schult. Ostrea rivularis Gould, Artemisia japonica Thunb., Rattus Calathodes Oxycarpa Sprague, Viburnum setigerum Hance, norvegicus Berkenhout, Laportea sinensis C. H. Wright, Incarvillea delavayi Bur. et Franch. Polygonum amplexi Canis familiaris L., P1134, Dicranostigma leptopodum caule D. Don var. Sinense Forb. et Hemsl., Prunus Simonii (Maxim.) Fedde, Bredia amoena Diels, Polygonum multiflo Carr., Spatholobus suberectus Dunn, Mucuna birdwoodiana rum Thunb., Cynanchum bungei Decne. C. auriculatum Tutcher, Millettia dielsiana Harms, Millettia initida Benth., Royle ex wight, Lycopodium obscurum L., L. Cernnum L., Sargentodoxa cuneata (Oliv.) Rehd. et wils. Mucuna semi Tixospora sinensis (Lour.) Merr., Bretschneidera sinensis pervirens Hemsl., Millettia reticulata Benth., Chrysopogon Hemsl., Polygonum Coriaceum Samuels., Lycianthes lysima aciculatus (Retz.) Trin. Elsholtzia blanda (Benth.) Benth. chioides (wall.) Bitt., Citrus medica L. var. sarcodactylis Habenariadelavayi Finet, Habenaria densa wall. Parnassia (Noot.) Swingle, Sedum lineare Thunb., Briggsia chingii wightiana wall. Viburnum Sargentii Koehne, Abrus fruticu (Merr.) Chun, Sedum multicaule wall. Aquilaria agallocha losus wall. ex wight et Arm. Groton crassifolius Geisel. Roxb., A. Sinensis (Lour.) Gilg, Kalanchoe laciniata (L.) D Dipelta ventricosa Hemsl., Celosia Cristata L., Potentilla C., Gleditsia sinensis Lam., Salix wallichiana Anderss. bifurca L., Gallus gallus domesticus Brisson, Paederia scan Gleditsia horrida Mak. Mimosa pudica L., Oryza sativa L., dens (Lour.) Merr., Dioscorea cirrhosa Lour., Tripterygium Setaria italica (L.) Beauv. Circaea quadrisulcata (Maxim.) wilfordii Hook.f., Boehmeria nivea (L.) Gaud. Plumbagella Franch. et Sav. Eriocaulon buergerianum Koern., Eriocau micrantha (Ledeb.) Spach, Kummerowia striata (Thunb.) lon Sieboldtianum Sieb. et Zucc. ex Stend. E. nudicuspe Schindl., Kummerowia stipulacea (Maxim.) Mak. Oxytropis Maxim., E. Sexangulare L., E. australe R. Br. Kadsura coc myriophylla (Pall.) DC., Berberis chingii Cheng, Plumeria cinea (Lem.) A. C. Smith, Zephyranthes candida Herb., rubra L. var. acutifolia (Poir.) Bailey, Codonopsis convolvu Triplostegia glandulifera wall. Ligularia laesicotal Kitam. lacea Kurz, Cornus capitata wall. Desmos cochinchinensis L. tsangchanensis (Franch.) Hand.-MaZZ., Coelogyne occul Lour., Stellaria neglecta weihe, Euphorbia esula L., Vibur US 2009/01 04295 A1 Apr. 23, 2009

num Sargentii Koehne, Pogostemon glaber Benth. Paederia Mahonia ganpinensis (Levl.) Fedde, Mahonia fortunei scandens (Lour.) Merr., Epipactis papillosa Franch. Gen (Lindl.) Fedde, Berberis anhweiensis Ahrendt, Cirsium bel darussa vulgaris Nees, Psychotria siamica (Craib) Hutch. ingschanicum Petr., Erinaceus europaeus L., Robinia Equus asinus L., Crepis turczaminowi C. A. Mey. Dendro pseudoacacia L., Tribulus terrestris L., Smilax nana wang, bium moniliforme (L.) Sw., Rosa rugosa Thunb., Citrus tan Euonymus wilsonii Sprague, Caesalpinia Crista L., Celastrus gerina Hort. et Tanaka, C. erythrosa Tanaka, Citrus sinensis flagellaris Rupr., Kalopanax Septemlobus (Thunb.) Koidz., (L.) Osbeck, C. wilsonii Tanaka, C. chachiensis Hort. Mylo Morina Coulteriana Royle, Eragrostis pilosa (L.) Beauv., pharyngodon piceus (Richardson), Aster faberi Franch. Scutellaria Orthocalyx Hand.-MaZZ. Jasminum Sambac (L.) Celosia argentea L., Rana nigromaculata Hallowell, Rana Ait. Lactuca taiwaniana Maxim. Momordica charantia L., plancyi Lataste, Allium sativum L., Artemisia apiacea Hance, Lactuca versicolor (Fisch.) Sch.-Bip., Cirsium chinense Artemisia annua L., Artemisia capillaris Thunb., A. scoparia Gardn. et Champ. Solanum dulcamara L., Sophora flave waldst. et Kitaib., Artemisia japonica Thunb., Avena nuda L., scens Ait., Vallisneria spiralis L., Synedrella modiflora (L.) Clinacanthus nutans (Burm. f.) Lindau, Baphicacanthus Gaertn., Sonchus oleraceus L., Centaurea picris Pall. Physa cusia (Nees) Brem. Indigofera tinctoria L., Isatis tinctoria lis pubescens L., Ilex cornuta Lindl., Ilex latifolia Thunb. L. I. indigotica Fort. Polygonum tinctorium Ait., Nervilia Ligustrum pedunculare Rehd., L. japonicum Thunb. Var. fordii (Hance) Schltr., Aristolochia debilis Sieb. et Zucc., pubescens Koidz., Sophora alopecuroides L., Caesalpinia Aristolochia contorta Bge., Aristolochia kaempferi willd.; A. minax Hance, Corydalis bungeana Turcz., Elephantopus chui C. Y. wu, Vladimiria berardioides (Franch.) Ling, scaber L., Elephantopus tomentosus L., Pleioblastus amarus Viadimiria forrestii (Diels) Ling, Vladimiria edulis (Franch.) (Keng) Keng L., Sophora alopecuroides L., Astragalus Ling, Sinomenium acutum (Thunb.) Rehd. et wils. Diplocli melilotoides Pall. Picrasma quassioides (D. Don) Benn., sia chinensis Merr., Sabia japonica Maxim. Cocculus trilo Fagopyrum tataricum Gaertn., Ligustrum japonicum thunb. bus (Thunb.) DC., Paederia scandens (Lour.) Merr., Hedera var. pubescens Koidz., Ixeris denticulata (Houtt.) Stebb. nepalensis K. Koch var. Sinensis(Tobl.) Rehd., Swertia vac Lagenaria Siceraria (Molina) Standl. Var. gourda Ser. Puer illans (Hance) Maxim. Swertia pulchella (D. Don) Buch.- aria Omeiensis wang et Tang, Melia azedarach L., Melia Ham... S. nervosa wall. Lycopodium hamiltonii Spr., toosendan Sieb. et Zucc., Ixeris Sonchifolia (Bge.) Hance, I. Hypoestes purpurea (L.) Soland. Rhaphidophora hongkon Sonchifolia (Bge.) Hance var. serotina (Maxim.) Kitag., Mil gensis Schott, Trimeresurus Stejnegeri Schmidt, Cynanchum lettia pachycarpa Benth., Scorzonera divaricata turcZ. Otophyllum Schneid., Ouercus variabilis Bl. Quercus semi Loranthus chinensis D.C., Brassica caulorapa Pasq., Mar carpifolia Smith, Prinsepia utilis Royle, Mylopharyngodon silea quadrifolia L., Malus pumila Mill. Medicago sativa L., piceus (Richardson), Aristolochia calcicola C. Y. Wu, Des Medicago hispida Gaertn., Medicago hispida Gaertn. Var. modium caudatun (Thunb.) DC., Lytta caraganae Pallas, denticulata, M. hispida Gaertn. Var. denticulata, Clematis Celosia argentea L., Rana nigromaculata Hallowell, R. plan glauva willd.; Abutilon theophrasti Medic. Rosa bracteato cvi Lataste, Artemisia apiacea Hance, A. annua L., Setaria wendl., Boehmeria nivea (L.) Gaud. Asarum insigne Diels, italica (L.) Beauv., Cocculus trilobus (Thunb.) DC., Lysiono Solanum melongena L., P1311, Castanea Seguinii Dode, tus serratus D. Don, Ainsliaea rubrinervis Chang, Roegneria serotina Keng, Hierochlo Odoranta (L.) Beauv., Tripterospermum japonicum (Sieb. et Zucc.) Maxim. Cordia Castanea henryi (Skan) Rehd. et wils. Drosera peltata Smith dichotoma Forst. F., P1244. Desmodium caudatum (Thunb.) var. lunata (Buch.-Ham.) C. B. Clarke, Monochoria korsa D.C., Rhus potanini Maxim. Rhus chinensis Mill., P1244, kowii Reg. Et Maack, Curcuma aromatica Salisb., Curcuna Aster lasiocladus Hayata, Pileostegia viburnoides Hook.f. et Zedoaria (Berg.) Rosc., Prunus japonica Thunb., Prunus Thoms. Saxifraga przewalski Engl. Gymnema Sylvestre humilis Bge. Prunus japonica Thunb. Var. nakai (Levl.) (Retz.) Schult. Malus asiatica Nakai, Rhus succedanea L., Rehd., Tulipa gesneriana L., Delphinium monanthum Hand.- Lespedeza davurica (Laxm.) Schindl., Cyathula prostrata MaZZ., Pittosporum Oligocarpum Hayata, Sida Szechuensis (L.) Bl, Eriobotrya japonica (Thunb.) Lindl., Xvlanche Matsuda, Lagerstroemia subcostata Koehne, Drymoglossum himalaica G. Beck, Isatistinctoria L., Isatis indigotica Fort. piloselloides (L.) Presl, Clematis Clarkeana Levl. et Vant. Baphicacanthus clusia (Nees) Brem. Pinus tabulaeformis Veratrum taliense Loes. F., Ainsliaea lancifolia Franch. Carr., Pinus massoniana Lamb., Pinus yunnanensis Franch. Senecio argumensis Turcz., Veronicastrum Sibirica (L.) Pen Usnea longissima Ach. Usnea diffracta Vain., Phtheirosper nell, Veronicastrum Sibirica (L.) Pennell. Var. japonicum, mum japonicum (Thunb.) Kanitz, Sciurus vulgaris L., Armill Oxytropis chilliophylla Royle, Actinidia arguta (Sieb. et aria matsutake Itoet Imai, Picris hieracioides L. Subsp. Zucc.) Planch. Atriplex sibirica L., Thalictrum ramosum japonica Krylov, Pterocarya Stenoptera D.C., Dendropanax Boivin, Arsenopyrite, Iris tectorum Maxim. Milvus korschun chevalieri (Vig.) Merr., Liquidambar taiwaniana Hance, Vis lineatus (Gray), Odontites serotina Reich. Eritrichium cum articulatum Burm. f. Broussonetia kazinoki Sieb. et rupestre (Pall.) Bge. Lindernia ciliata (Colsm.) Pennell, Zucc. Lindera umbellata Thunb., Ribes alpestre wall. ex Schizophragma integrifolium Oliv. f. denticulatum (Rehd.) Decne. Morina delavayi Franch. Trapa incisa Sieb. et Zucc. Chun, Polygonum cuspidatum Sieb. et Zucc., Damnacanthus var quadricaudata Gluck, Rubus hirsutus Thunb., Rosa rox indicus Gaertn. f. Panthera tigris L., Anectochilus taiwanen burghii Tratt. F. normalis Rehd. et wils., Hemiptelea davidii sis Hayata, Chrysosplenium macrophyllum Oliv. Saxifraga (Hance) Planch, Alhagi pseudalhagi DesV., Chenopodium stolonifera (L.) Meerb., Sansevieria trifasciata Prain, aristatum L., Oplopanax elatus Nakai, Acanthopanax trifo Sansevieria trifasciata Prain var. laurentii N. E. Br. Uraria liatus (L.) Merr., Solanum khasianum C. B. Clarke, Rosa crimita DeSV, Delphinium tatsienense Franch. aff, Anemone Omeiensis Rolfe, Aralia elata (Miq.) Seem. Bambusa sinos rivularis Buch-Ham. Corallodiscus cordatulus (Craib) B. L. pinosa McClure, Salsola ruthenica Iljin, Rosa davurica Pall. Burtt, Nephrolepis cordifolia (L.) Presi, Veronica persica Erythrina variegata L. var. Orientalis (L.) Merr., Rosa gra Poir. Ainsliaea spicata Vant. Var. Obovata (Franch.) C.Y. wu, ciliflora Rehd. et wils. Smilax ferox wall. ex Kunth, Berberis Pandanus furcatus Roxb., Patrinia villosa Juss. Patrinia sca soulieana Schneid. Mahonia gracilipes (Oliv.) Fedde, biosaefolia Fisch. Sonchus brachyotus D.C., Thlaspi arvense US 2009/01 04295 A1 Apr. 23, 2009

L., Changium Smyrnioides Wolff, Moghania fluminalis (C. B. longepedunculatum O. C. Schmidt, Coleus pumilus Blanco, Clarke) Li, Rodgersia Sambucifolia Hemsl., Rodgersia pin Smilax Scobinicaulis c. H. Wright, Smilax glauco-china nata Franch. Sedum leucocarpum Franch. Sinocrassula warb., Ampelopsis delavayana (Franch.) Planch. Smilax indica (Decne.) Berger, Thunia alba (Lindl.) Reichb.f., Zan bockii warb., Lotus tenuis Kitag., Pteris dactylina Hook. thoxylum acanthopodium D C. Var, villosum Huang, Obero Cinchona succirubra Pav., Cinchona ledgeriana Moens., C. nia myosurus (Forst.) Lindl., Artemisia brachyloba Franch. calisaya wedd., C. officinalis L., Triunfetta pilosa Roth, Kyl Codonopsis purpurea wall. Melodinus henryi Craib, linga triceps Rottb., Bungarus fasciatus (Schneider), Tino Dichocarpum dalzielii (Drumm. et Hutch.) w. T. wang et spora capillipes gagn. Tinospora imbricata S.Y. Hu, Poten Hsiao, Bergenia purpurascens (Hook. f. et Thoms.) Engl. tilla reptans L. var. sericophylla Franch. Inula britannica L. Bergenia crassifolia (L.) Fritsch, Boea crassifolia Hemsl. var. Chinensis (Rupr.) Reg., I. linariaefolia Turcz. I. britan Thalictrum ichangense Lecoy. ex Oliv., Rhodobryum gigan nica L., Cladonia fallax Abbayes, Percocypris grahami teum (Hook.) Par. Dracocephalum rupestre Hance, Patrinia (Regan), Antenoron filiforme (Thunb.) Robertvet Vautier, rupestris Juss. Ophiorrhiza japonica Bl. Var. leiocalyx Antenoron neofiliforme (Nakai) Hara, Carpesium divarica Hand.-MaZZ. Lysionotus carnosa Hemsl., Briggsia fritschii tum Sieb. et Zucc., Phymatopsis griffithiana (Hook.) J. Sm. (Levl. et Vant.) Craitb, Bergenia purpurascens (Hook. f. et Calendula arvensis L., Calendula officinalis L., Trollius chin Thoms.) Engl. Corydalis thalictrifolia Franch. Boenning ensis Bge. Trollius asiaticus L., Glechoma longituba (Nakai) hausenia albiflora (Hook.) Meissn., B. sessilicarpa Levl. Kupr., Lysimachia Christinae Hance, Psammosilene tuni Boeninghausenia albiflora Meissn. var. japonica S. Suzuki, coides w. C. Wu et C.Y. wu, Clematis huchouensis Tamura, Berneuxia thibetica Decne. Vaccinium delavayi Franch. Caragana sinica (BuchoZ) Rehd., L. dasystyla Rehd., L. Campanula colorata wall. Millettia kweichowensis Hu, similis Hemsl., L.fitchsioides Hemsl., L. henryi Hemsl., L. Impatiens davidii Franch. Epiphyllum oxypetalum Haw. lanceolata wall. Hyla chinensis Ginther, Hyla regilla, wik Laminaria japonica Aresch. Ecklonia kurome Okam. stroemia mutans Champ., Vermiculite, Rosa laevigata Undaria pinnatifida (Harv.) Sur., Aconitum villmorinianum Michx., Rosa bella Rehd. et wils., R. Odorata Sweet var. Kom. Millettia reticulata Benth., Berberis kunmingensis C. gigantea Rehd. et wils., R. macrophylla Lindl., Ainsliaea Y. wu, Berberis pruinosa Franch., Ocimum basilicum L., fragrams Champ., Clematis loureiriana DC. var. Subpeltata Apocynum venetum L., Momordica grosvenori Swingle, (wall.) Hand.-MaZZ., Euonymus yunnanensis Franch. Hemsleya macrosperma C. Y. Wu, Hemsleya amabilis Diets, Parameria laevigata (Juss.) Moldenke, Pittosporum glabra Hemsleya chinensis Cogn. Thladiantha hookeri C. B. tum Lindl. Var. neriifolium Rehd. et wils. Smilax glauco Clarke, Crinum asiaticum L. var. Sinicum Bak. Podocarpus china warb., Amphicome arguta (Royle) Lindl., Bidens pilosa macrophyllus (Thunb.) D. Don var. maki (Sieb.) Endi., P. L., Bidens biternata (Lour.) Merr. et Sherff, Limonium macrophyllus (Thunb.) D. Don, Podocarpus forrestii Craib et aureum (L.) Hill, Paliurus hemsleyanus Rehd., Lonicera w. W. Smith, Bulbophyllum odoratissimum (J. E. Smith) japonica Thunb., Agave americana L. var. marginata Hort. Lindl., Bos grunniens L., Thermopsis lanceolata R. Br. Agave americana L., Agave schottii, Rhododendron przew Chlorophytum capense (L.) Ktze. Neillia sinensis Oliv., alski Maxim. Chrysosplenium grayanum Maxim. Mac Veronicastrum axillare (Sieb. et Zucc.) Yamazaki subsp. rothelypteris Oligophlebia (Bak.) Ching, Macrothelypteris venosum (Hemsl.) Hong, Veronicastrum axillare (Sieb. et Oligophlebia (Bak.) Ching var. elegans (KoidZ.) Ching, Phe Zucc.) Yamazaki Subsp. latifolium (Hemsl.) Hong, Veronicas gopteris decursive-pinnata Fe, Vulpes vulpes L., Uraria trum axillare (Sieb. et Zucc.) Yamazaki Subsp. Stenostachyum lagopodioides (L.) DesV., Canis familiaris L., Cibotium (Hemsl.) Hong, Lindera umbellate Thunb., Luisia morsei baromets (L.) J. Sm., woodwardia japonica (L. f.) Sm. Huo Rolfe, waltheria americana L., Lespedeza davidii Franch. lirion montana (Dammer) wang et Tang, Stizolobium Cucubalus baccifer L. var. japonicus Miq., Hordeum vulgare cochinchinensis (Lour.) Tang et wang, Machilus bracteata L. var. nudum Hook. f. Anemarrhena asphodeloides Bge. Lecomte, Senecio integrifolius (L.) Clairvill var. fauriei Excoecaria acerifolia F. Didr., Potentilla chinensis Ser. (Levl. et Vant.) Kitam. Dicliptera chinensis (L.) Nees. Des Amaranthus spinosus L., Lasia spinosa (L.) Thw., Euonymus modium heterocarpum (L.) DC., Setaria viridis (L.) Beauv., Oxyphylla Miq., Malus halliana Koehne, Arabis pendula L., Setaria glauca (L.) Beauv., Calystegia japonica Choisy, Seri Quisqualis indica L., Biota Orientalis (L.) Endl., Cupressus cocalyx chinensis (Nees) Brem. Cynoglossum amabile Stapf torulosa D. Don, Sabina recurva (Buch-Ham.) Antoine, et Drumm., Phyllanthus cochinchinensis Spr., Disporum cal Eupatorium fortunei Turcz., Eupatorium cannabinum L., caratum D. Don. Craibiodendron stellatum (Pier.) w. w. Begonia cavalerei Levl., Rhaphidophora decursiva (Roxb.) Smith, Vaccinium laetum Diels, P1429, Parnassia delavayi Schott, Campylotropis trigonoclada (Franch.) Schindl., Franch. Crawfurdia fasciculate wall. Crawfurdia chinensis Boswellia carterii Birdw. Boswellia bhaw-daiiana Birdw. Migo, Gymnocladus chinensis Baill. Senecio Oldhamianus B. neglecta M. Moore, P1381, Anaphalis lactea Maxim. Maxim. Lepus tolai Pallas, Lepus mandschuricus Radde, Anaphalis lacteal Maxim. f. rosa Lang, Viola philippica Cav., Lepus Oiostolus Hodgson, Lepus sinensis Gray, Oryctolagus Carassius auratus (L.), Paraphlomis rugosa (Benth.) Prain cuniculus domesticus (Gmelin), Ainsliaea glabra Hemsl., var. coronata (Vant.) C.Y. wu, Native gold, Fortunella mar Syneilesis aconitifolia Maxim. Tanacetum Sibiricum L., garita (Lour.) Swingle, Fortunella Crassifolia Swingle, For Pecteilis Susannae (L.) Raf. Alcedo atthis bengalensis Gime tunella japonica (Thunb.) Swingle, Callicarpa kwangtun lin, Chara fragilis DesV, Derris trifoliata Lour. Ichthyoxenus gensis Chun, Stephania sinica Diels, Aconitum taipeicium tchangi Yu, Mentha rotundifolia (L.) Huds. Swertia davidi Hand.-Mazz., Polygala telephioides willd.; Astilbe myrian Franch. Dichrocephala benthamii C. B. Clarke, Dichro tha Diels, Lysimachia grammica Hance, Ouamoclit pennata cephala chrysanthemifolia (Bl.) DC., Houttuynia cordata (Lam.) Boi. Craibiodendron yunnanense W. W. Smith, Dis Thunb., Lepidogrammitis drymoglossoides (Bak.) Ching, chidia chinensis Champ. ex Benth. Dischidia australis Tsi Cyrtonium fortunel J. Sm., Ajuga lupulina Maxim. Magno ang, Alectoria virens Tayl. Melica scabrosa Trin. Hyperi lia coco (Lour.) DC., Lespedeza cuneata (Dum. Cours.) G. cum chinense L., Trichosanthes obtusiloba C. Y. Wu, Asarum Don, Hypserpa initida Miers, Selaginella involvens (Sw.) US 2009/01 04295 A1 Apr. 23, 2009

Spring, P1447, Rhododendron molle (Bl.) G. Don, Rhodo naka, Citrus Suhoiensis Tanaka, C. poonensis Tanaka, C. dendron hunnewellianum, R. japonicum Suringer, Alstonia tankan Hayata, Lithocarpus glaber (Thunb.) Nakai, Kopsia mairei Levl., Smithsonite, Fugu Ocellatus (Osbeck), Fugu officinalis Tsianget P. T. Li, Cudrania tricuspidata (Carr.) vermicularis (Temminck & Schlegel), Fugu Obscurus (Abe), Bur, Abrus precatorius L., Citrus grandis (L.) Osbeck, Cit Pseudogyrinocheilus procheilus (Sauvage et Dabry), Lep rus grandis (L.) Osbeck var. wentanyu Hort., C. grandis (L.) tochloa chinensis (L.) Nees, Aleurites fordii Hemsl., Aleu Osbeck var. Shatinyu Hort., C. grandis (L.) Oseck var. Pins rites montana, P1455, Symplocos laurina (Retz.) wall. Oxyt hanyu Hort., C. grandis (L.) Osbeck var. Szechipow Hort., C. ropis Oxyphylla D. C., Leycesteria virescens Lindl., C. grandis (L.) Osbeck var. tahungpow, Hort. Viscum Orientale pumilum Rolfe, P1474, Hemiboea subcapitat c. B. Clarke, willd. Citrus aurantium L., Citrus sinensis (L.) Osbeck, C. Dalbergia Odorifera T. Chen, Acronychia pedunculata (L.) medica L. anche caerulescens Steph., Orobanche pyc Mid, Pulicaria insignis Drumm. Cirsium lineare (Thunb.) nostachya Hance, Orobanche asiatica Kirschl. O. rapun Sch.-Bip. Var. pallidum (Kitam.) Ling, Cirsium lineare Sch.- genistae Thuill. Tephrosia purp Bip., Coreopsis lanceolata L., Asarum heterotropoides F. Though it is not restricted especially, Traditional Chinese Schm. Var. mandshuricum (Maxim.) Kitag., Asarum sieboldi medicine or/and its extracts, granulated powdered medicines Miq., Asarum forbesii Maxim. A. maximum Hemsl., A. geo manufactured from natural plants, animal parts, or mineral philum Hemsl., A. Caudigerum Hance, A. himalaicum Hook. Substances, for instance, the following can be enumerated f. et Thoms. A. Caulescens Maxim. A. longiflorum C. Y. (the traditional medicine names are represented in their Japa Cheng et C. S. Yang, A. insigne Diels, A. longipedunculatum nese pronunciation); Tsumuratou, Tsumuratou kasenky O. C. Schmidt, A. Sieboldlii var. Seoulensis Nakai, A. Sieboldii ushini, Oji-tou, Ancyluusan, Jyuumihandokusan, Hachim var. cineoliferum, Asarum europaeum, Ceratophyllum dem ijiogan, Daisaikotou, Syousaikotou, Saikokeishitou, ersum L., Allium Schoenoprasum L., Euphorbia esula L. var. Saikokeishikankyoutou, Saikokaryukotsuboreitou, Hanges cyparissoides Boiss., Eucalyptus tereticornis Smith, Mur yashintou, ourengeddokutou, Hangekoubokutou, Goreisan, dannia simplex (Vahl) Brenan, Teucrium pernyi Franch. Jus Keishikajyutsufutou, Syouseiryuutou, Boujiougitou, Syou ticia leptostachya Hemsl., Lespedeza chinensis G. Don, hangekabukuryoutou, Syoufuusan, Toukisyakuyakusan, Hypecoum leptocarpum Hook.f. et Thoms. Dryopteris cras Kamisyouyousan, Keishibukuryougan, Keishikaryukotsub Sirhizoma Nakai, Lunathyrium acrostichoides (Sw.) Ching, oreitou, Maoutou, Ebbikajyutsutou, Makumontou, shinb Matteuccia struthiopteris (L.) Todaro, Osmunda japonica utou, Gosyuyutou, Ninjintou, Daioubotanpitou, Byakkou Thunb., Blechnum Orientale L. Brainia insignis (Hook.) J. kaninjintou, Shigyakusan, Mobougitou, Sm., woodwardia japonica (L. f.) Sm. Dryopteris peninsulae Hangebyakujyutsutenmatou, Toukishigyakukagosyuyusy Kitag., woodwardia unigemmata (Mak.) Nakai, Polystichum oukyoutou, Ryoukeijyutsukantou, Cyoreitou, Hocyuuekitou, squarrosum Fe, Dryopteris filixmas (L.) Schott, Cyrtonium Rikkushitou, Keishitou, Shichimotsukoukatou, Koutousan, fortunei J. Smith, Hypericum perforatum L., Mactra sul Jyuzendaihotou, Keigairengyoutou, Juncyoutou, Yokuinin cataria Deshayes, Corallium japonicum Kishinouye, tou, Sokeikakketsutou, Yokkansan, Mashinkansekitou, Gor Spatholirion longifolium (Gagn.) Dunn, Eretnochelys imbri insan, Onselin, Seiyouboufuutou, Chitousouichihou, Keish cata (L.), Citrus aurantium L. var.amara Engl. Pteria mar ikasyakuyakutou, Toukakusyoukitou, Boufuutsuusyousan, garitifera (L.), Pteria martensii (Dunker), Callicarapa bodi Gosekisan, Syakukanzoutou. Kihitou, Jinsouin, Nyojinsan, nieri LV1. Ardisia maculosa Mez, Phyllanthus urinaria L., Syakuyakukanzoutou, Bukuryousan, Shimotsutou, Kan Thalictrum trichopus Franch. Sorbaria arborea Schneid., makutaisoutou, Saikantou, Cyouisyoukitou, Shikushitou, Sorbaria sorbifolia (L.) A. Br. Lysimachia clethroides Duby, Ryutansyakantou, Toukikyouaitou, Mashinsekikantou, Hei Cyanotis arachnoidea C. B. Clarke, Cicuta virosa L., Millet isan, Saikoseikantou, Nichintou, Keishininjintou, Yokkan tia lasiopetala (Hayata) Merr. Botrychium virginianum (L.) sankachipihange, Daioukanzoutou, Shinpitou, Toukuinshi, Sw., Rhaphiolepis indica (L.) Lindl., Lespedeza dunnii Rokumigan, Nijyutsutou, Chidabokuichihou, Seihaitou, Schindl., Citrus chachiensis Hort., Citrus Suavissima Tatai Ondantou, Jinchihoutou, Jionkoukatou, Gokoutou, Sai wanensis wall. Var. glandulosissima Airy-Shaw, Physoch pokutou, Daiboufuutou, Ougikencyuutou, Syoukencyuutou, lana physaloides (L.) G. Don, Catalpa fargesii Bur., Misgur Daikencyuutou, Syoumatou, Toukitou, Sansounintou, Shin nus anguillicaudatus (Cantor), Hemistepta Carthamoides iseihaitou, Tsuutousan, Onkeitou, Gosyajinkigan, Ninjin (Buch.-Ham.) O. Ktze. Misgurnus anguillicaudatus (Can youeitou, Syousaikotoukakikkyo Sekkou, Rikkousan, Seish tor), Artocarpus heterophyllus Lam., Herpetospermum cau in renshiin, Cyoreitougoushimotsutou, Sanousyashintou, digerum wall. Lycopus lucidus Turcz., Lycopus lucidus Saireitou, Ireitou, Bukuryouingouhangekoubokutou, Gore Turcz. var. hiritus Reg., L. lucidus Turcz. var. taiwanensis isan, Ryoukyoujyutsukantou, Ryoukankyoumishingenintou, Hayata, L. parviflorus Maxim. L. maackianus (Maxim.) Ourentou, SanmotSuougontou, Hainousan, Hainoutou, Mak. L. Coreanus Levl., L. europaeus L., Alisma plantago Toukikencyuutou, Sencyacyousan, Keishibukuryouganka aquatica L. var. Orientale Samuels, Euphorbia helioscopia mashiningan, mashiningan, Maoubushisaishintou, Keihitou, L., Lysidice rhodostegia Hance, Lysimachia candida Lindl., Daisyoukitou, Keishikadaioutout, Inchinkoutou, Seisyoeki Ervatamia hainaensis Tsiang, Aster turbinatus S. Moore, tou, Kamikihitou, Kikkyotou, Shiyunkou, Syouyakukoujin, Salvia cavaleriei Levl. Var. Simplicifolia Stilb., Lamium Shouyakushuuzibushi, Meta light, Astattocrem, Astat liquid, amplexicaule L., Angiopteris officinalis Ching, Lindernia Astat ointment, Shinfaz, and Toconshiropp, Heisanryou, anagallis (Burm. f.) Pennell, Trichosanthes himalensis C. B. Atsushikiyoshiin, Goreisanryou, Kobushiseihaitou, Clarke, AZurite. Alternanthera philoxeroides (Mart.) Griseb. Boukiougitou, Saikokaryukotsuboreitou, Shinpitou, Boufuut Maesa perlarius (Lour.) Merr., Spiraea salicifolia L., Crepis SuSeisanryou, Ourentou, Saikokeishikankyoutou, hookeriana C. B. Clarke, Selaginella tamariscina (Beauv.) Sokeikakketsutou, Saikokeishitou, Daisaikotou, Mashin Spring, Selaginella pulvinata (Hook. et Grev.) Maxim. Cor kansekitou, Kakkontou, Saikoseikantou, Koutousanryou, allodiscus kinginus (Craib) B. L. Burtt, Epilobiumhim alay Mashinkantout, Kakontoukasenshini, Sanousyashintou, ense Hausskin. Cymbidium ensifolium (L.) Sw., Cymbidium Cyoreitou, Mokuboukitou, Toukishigyakukagosyuyusyou US 2009/01 04295 A1 Apr. 23, 2009 20 kyoutou, Yokukansankachinpihange, Toukisyakuyakusan 0074. In this mode of the agent for hair growth, it is pref ryou, Rikkunshitou, Keishikaryuukotsuboreitou, Jyuumihan erable to obtain enough of a synergetic effects in hair growth dokutou, Hangekoupukutou, Ryuutansyakantou, by mixing the ingredients under the following conditions; Oncyushitsuutou, Onselin, Ourentou, Sofuuteitsuutou, Yok blend “a parts by weight of the processed semi-mature soy kansankachinpihangetou, Junketsuonhotou, Ryuudansya bean and “b’ parts by weight of the processed semi-mature kantou, taiyousoubitou, Shiyakuonketsutou, Kaikinshits soybean extracts (wherein “a” and “b' are numbers that are uutou, Oncyuushitsuutou, keishitou, Syousyouyoujyou, not less than 0, and fill a relation of a+b=100) with Hyoushitsuseicyoujyou, Onselin, Keireianjunjyou, (0075 “c” parts by weight of the processed Polygoni Mul Syouseiryuutou, Kouhiseikenyou, Ourentou, Gomir tiflori Radix, “d parts by weight of the processed Polygoni isuiyou, Hocyuukaikiyou, Seinetsu Syahiyou, Ourenged Multiflori Radix extracts, “e' parts by weight of the processed dokutou, Ryuukajunselyou, Soukoujunkiyou, Kougy Cynanchum bungei Decne and “f parts by weight of the akusuikiyou, Tenchitsuucyoujyou, Hanrikaiyoujyou, processed Cynanchum bungei Decne extracts (wherein 'c'. ShimosyoutsuuSuiyou, Kaihyousoukinyou, Sansounintou, 'd', 'e', and “fare numbers that are not less than 0, and fill Futokuanjunjyou, Kakkontoukasenshini, Shiyakuonket a relation of 3 sc--d--e--fs 100, preferably 20s.c+d+e+fs60, Sutou, Shimotsutou, Makumontou, Hangekoupokutou, for example, c--d--e--f=40). Keigairengyoutou, Hyoukaireiyoujyou, Cyuusyoukenwa 0076 Moreover, a more desirable mode of the agent for you, Hangesyashintou, Ougegankadaiou, Ourengedokugan, hairgrowth of the invention is achieved by containing Longan Kankyouninjinhangegan, Kuketsugan, Keishibukuryougan, seed and/or Longan seed extracts as active ingredients into the Keiryoukadaiougan, Sanougan, Daikangan, Toukakusyouki above-mentioned ingredients. gan, Mashiningan, Ricyuugan, Rokumigan, Hachimigan, 0077. In this mode of the agent for hair growth, it is pref Ancyluusanr Kamisyouyousan, Syoufuusan, tsuudousan, erable to obtain enough of a synergetic effects in hair growth Toukisyakuyakusan, Hainosan, Heisan, Ninjinyoueitou, (especially improving the color and luster of hair) by mixing Daioukanzoutou, Kamikihitou, Toukisyakuyakusan, Hocy the ingredients at the rates under the following conditions; uuekitou, Sairyoutou, Saikokeishitou, Goryousan, Keishi blend “a parts by weight of the processed semi-mature soy bukuryougan, keishikajyutsufutou, Kamisyouyousan, Kakk bean and “b’ parts by weight of the processed semi-mature ontou, Ourengedokutou, etc. soybean extracts (wherein “a” and “b' are numbers that are 0069 All the drugs authorized by the Japan Ministry of not less than 0, and fill a relation of a+b=100) and Health and Welfare can be enumerated. 0078 “c' parts by weight of the processed Polygoni Mul tiflori Radix, “d parts by weight of the processed Polygoni “Compositions of the Active Ingredients of the Agent for Hair Multiflori Radix extracts, “e' parts by weight of the processed Growth Cynanchum bungei Decne and “f parts by weight of the 0070 The processed semi-mature soybean, the processed processed Cynanchum bungei Decne extracts (wherein 'c'. semi-mature Soybean extracts, the processed Polygoni Mul 'd', 'e', and “fare numbers that are not less than 0, and fill tiflori Radix, the processed Polygoni Multiflori Radix a relation of 3 sc--d--e--fs 100, preferably 20s.c+d+e+fs60, extracts, the processed Cynanchum bungei Decne, the pro for example, c--d--e--f=40) with cessed Cynanchum bungei Decne extracts and the Longan 0079 “g parts by weight of the Longan seed and “h” parts seed have the hair growth effects respectively. by weight of the Longan seed extracts (wherein 'g' and “f 0071. However, this invention obtained synergistic effects are numbers that are not less than 0, and fill a relation of of hair growth by blending the processed semi-mature Soy 2sg+hs30, preferably 4sgishs 12, for example, g-h 8). bean and/or its extracts and at least one substance selected from the group consisting of the processed Polygoni Multi “The Mode of the Agent for Hair Growth” flori Radix, its extracts, the processed Cynanchum bungei 0080. As far as efficacy is concerned, in the agent for hair Decne and its extracts. growth of this invention, oral administration is suitable. For 0072. In this invention, notable effects of hair growth can instance, the powder or liquid (extracts) form of the agent can be obtained with the addition of only small amounts of each of be taken by adding an additive such as Sweeteners if neces the processed Polygoni Multiflori Radix, the processed Cyn sary. As an example, Various forms of oral administration of anchum bungei Decne and Longan seed to the processed the agent for hair growth are enumerated semi-mature soybean. The ratio of the mixture of the pro I0081. These may include the liquid type such as syrup, an cessed semi-mature Soybean with the processed Polygoni ampuled liquid (beverages), and then tablet, capsule, powder, Multiflori Radix, the processed Cynanchum bungei Decne, fine granule and granulated powder form. In the case of oral and Longan seed is not especially restricted. It is possible to administration, a variety of well-known Substances such as adjust the amounts appropriately according to how the ingre bonding agents, forming agents, explosive puff agents, lubri dients are combined as well as the mode of the agent for hair cants, brightening agents, Sweeteners, and Zests, etc. can be growth, etc. The following ranges are one mode of this inven used for the agent for hair growth of this invention. Here, the tion and although they are desirable, one is not restricted tablets can be covered with shieracc or sugar. Moreover, the within them especially. capsule preparations may contain a liquid catalytic Support 0073. The agent for hair growth in this invention usually ing Substance such as oils and lipids amongst the materials contains a processed semi-mature soybean and/or a processed mentioned above. The syrup and ampuled liquid preparations semi-mature Soybean extracts, along with at least one Sub (beverages) may contain Sweeteners, preservatives, and col stance selected from the group consisting of a processed oring and flavoring Substances. Polygoni Multiflori Radix, processed Polygoni Multiflori I0082. Additionally, it is possible to take the agent for hair Radix extract, processed Cynanchum bungei Decne or pro growth of this invention together with the following foods: cessed Cynanchum bungei Decne extract as active ingredi Western-style cakes Such as cookies; Rice crackers, Sweet entS. jelly made from bean jam, Japanese-style confections such as US 2009/01 04295 A1 Apr. 23, 2009

Taiyaki, Chinese cakes such as Geppei, boiled dumplings 0090. In the processed semi-mature soybean, the typical etc.; or Chinese-style raw food substances; Foods in daily life taste of the raw soybeans was removed without pulverizing Such as breads, noodles, and rice balls etc.; various kind of the Soybeans by excessive heating. raw materials of food; Eating and drinking Substances such as candies and juices. One is not restricted by these additional “Making of the Processed Polygoni Multiflori Radix' methods. Various methods can be used when combining with 0091 Material: 1.0 kilogram of black soybean. 2.5 liters of conventional foods and beverages. In Such cases, the amount the Huangjiu (brandname: “Fuzhou Laojiu, Fuzhou Zhaojiu of the agent for hair growth of this invention used can be Chang, Fuzhou China). 10 kilograms of raw Polygoni Mul appropriately adjusted according to an individual’s eating and tiflori Radix. (cultivated in Shandong province, China, and drinking habits. obtained from Pinghe prefectural hospital, China.) 0083. When the agent for hair growth of this invention is 0092 Procedure 1: 1.0 kilogram of black soybeans is used orally, the frequency and the amount of intake can be added to 5 liters of water and brought to a boil by using a low properly adjusted to the relative conditions, it is not restricted flame for 3 hours to obtain 1.0 liter of hot water extract. 1.5 especially. liters of hot water extract is obtained with the second extrac 0084. For instance, intake of the agent twice a day at the tion. following times; when hungry in the early morning and 0093. Procedure 2: Mix 2.5 liters of the hot water extract before going to sleep at night. Also, the agent can be taken obtained in procedure 1 and 2.5 liters of Huangjiu. Then, add orally at a frequency ranging from once to several times a day. this mixed solution into 10 kilogram of raw Polygoni Multi To achieve the hair growth effects, ingesting 0.08g to 0.5 g/kg flori Radix, heat for about 10 hours by using hot water, soak body weight/day of the processed semi-mature Soybean is all of the black Soybean extracts and Huangjiu into the sufficient. The Japanese Ministry of Health, Labour and Wel Polygoni Multiflori Radix. fare recommends that the amount of the soybean intake is 76 (0094) Procedure 3: Dry the Polygoni Multiflori Radix g to 100g per day. “National health care movement of the 21st obtained in procedure 2 by using a natural drying method. century (health Japan 21)T(Ministry of Health and Welfare: “Making of the Processed Cynanchum bungei Decne' (0095 Material: 1.0 kilogram of black soybean, 2.5 liters of 2000). The agent for hair growth of this invention can achieve Huangjiu (brandname: “Fuzhou Laojiu, Fuzhou Zhaojiu noticeable results of hair growth even if it is ingested for only Chang, Fuzhou China). 10 kilograms of raw Cynanchum a short period of time, such as 6-12 weeks. bungei Decne. (cultivated in Shandong province, China, and 0085. In addition, the agent for hair growth of this inven obtained from Pinghe prefectural hospital, China.) tion can be used as an external hair tonic. In this way, it is 0096 Procedure 1: Add the 1.0 kilogram of black soy possible to apply it with various well-known hair treatment beans to 5 liters of water and boil by using a low flame for 3 methods, such as hair tonics, shampoos, rinses, hair condi hours, obtaining 1.0 liter of hot water extract. 1.5 liters of hot tioners, hair treatments, and Hearorshorn, hair creams, hair water extract is obtained with second extraction. oils, hair gels, ointments, powders, and granulated powders, 0097. Procedure 2: Mix 2.5 liters of the hot water extract etc. obtained in procedure 1 and 2.5 liters of Huangjiu. Then, add I0086. In hair tonic such externally, aside from the active this mixed solution into 10 kilograms of raw Cynanchum ingredients of this invention, materials such as drugs, quasi bungei Decne, heat for about 10 hours by using hot water, drugs, skin cosmetic, the cosmetic raw materials and various Soak all of the black soybean extracts and Huangjiu into the elements mixed with conventional hair tonics (for example, Cynanchum bungei Decne. materials for moisture preservation, Surface-active agents, (0098. Procedure 3: Dry the Cynanchum bungei Decne emulsifying agents, powders, coloring matters, solubilizers, obtained in procedure 2 by using a natural drying method. cleaning agents, ultraviolet ray absorbents, thickening agents, medicines, spices, pH adjustment materials, resins, anti-bac “Making of the Processed Longan Seed' terials, viral and mold materials, alcohols, esters, hydrocar bons, rows, and oils, lipids, fatty acids, etc.) can be properly (0099 Material: 1.0 kilogram of black soybeans, 2.5 liters mixed. Moreover, other compounds and other plant extracts of the Huangjiu (brandname: “Fuzhou Laojiu, Fuzhou Zha which have hair growth effects may be used together within a ojiu Chang, Fuzhou China). 10 kilograms of raw Longan certain range so as not to impair the effects of this invention. seeds (cultivated in Shandong province, China, and obtained 0087. It is desirable to apply the agent of this invention from Pinghe prefectural hospital, China.) externally from once to several times per day directly onto the 0100 Procedure 1: Add 1.0 kilogram of the black soy affected area. beans to 5 liters of water and boil by using a low flame for 3 hours, obtaining 1.0 liter of hot water extract. 1.5 liters of hot water extract is obtained with the second extraction. EXAMPLES 0101 Procedure 2: Mix 2.5 liters of the hot water extract obtained in procedure 1 and 2.5 liters of Huangjiu. Then, add 0088. The inventor explains this invention more con 10 kilograms of Longan seed to this mixed solution, heat for cretely in the following examples, but is not restricted by about 10hours by using hot water, soaking the Longan seed in them. all of the black Soybean extract and Huangjiu. 0102 Procedure 3: Dry the Longan seed obtained in pro “Making of the Processed Semi-Mature Soybean' cedure 2 by using a natural drying method. 0089. After a frying-pan was preheated in a gas stove, one kilogram of dry yellow soybeans was put into the frying-pan, Subject which were stirred with medium heat for three minutes; after 0103) In this invention, the subjects were 70 healthy indi which the semi-mature Soybean was obtained. viduals (59 males and 11 females) ranging in age from 29 to US 2009/01 04295 A1 Apr. 23, 2009 22

53 years old (the average age is 40.1+/-5.8 years old.) The 0.120. The raw Polygoni Multiflori Radix, the processed merits and risks of participating in this research experiment Polygoni Multiflori Radix powder, the raw Cynanchum were explained by myself to all the subjects and subsequently bungei Decne powder, the processed Cynanchum bungei received their approval. All subjects involved suffer from Decne powder, the Longan seed powder and the processed alopecia and/or thinning hair. Longan seed powder were taken twice per day—once before breakfast and again before retiring at night-time, with a dos The Groups and the Hair Restoration Ingredients age of 4 g each time, ingesting 8 g in total per day. 0104. The subjects were divided into 14 groups with each I0121 The Huangjiu was taken once per day before retiring group consisting of 5 individuals and received the following at night-time with a dosage of 200 ml each time. respective hair restoration powder Substances for oral con 0.122 The “compound ingredients 1’, the “compound Sumption. ingredients 2', the “compound ingredients 3 were taken 0105 1. The raw soybean group: the subjects ingested raw twice a day—once before breakfast and once before retiring yellow soybean powder (100%). at night-time, with a dosage of 12 g each time, ingesting 24g 0106 2. The processed semi-mature soybean group: the in total per day. Subjects ingested processed semi-mature Soybean powder Evaluation of State of Hair (100%). 0107 3. The mature yellow soybean group: the subjects I0123 Regarding the method of evaluating the extent of ingested mature yellow soybean powder (100%). This was alopecia and area of thinning hair, a well-known method was obtained by steaming the beans for two or more hours until adopted which includes dividing the area of thinning hair into having completely matured. six stages representing the following conditions: 0108 4. The boiled black soybean group: the subjects 0.124. A condition of normal health is termed “stage O'; no ingested boiled black soybean powder (100%). hair growing in the area of the forehead and the rest of the 0109) 5, The raw Polygoni Multiflori Radix group: the head as “stage 5': and stages between 0 and 5 are divided into subjects ingested dry raw Polygoni Multiflori Radix powder stages 1, 2, 3, and 4. When difficult to differentiate clearly, it (100%). was acceptable to use decimal values such as "0.5”. 0110 6, The processed Polygoni Multiflori Radix group: 0.125 Moreover, the degree of pain experienced when hair the subjects ingested processed Polygoni Multiflori Radix was pulled was divided into three stages as an index to evalu powder (100%). ate the effects of hair growth. That is, “degree 11 indicated 0111 7. The raw Cynanchum bungei Decne group: the mild-, "degree 2 moderate-, and “degree 3' strong pain Subjects ingested dry raw Cynanchum bungei Decne powder sensation. (100%). 0.126 This data was calculated by using the Student’s “t' 0112 8, The processed Cynanchum bungei Decne group: test with Microsoft Excel 2003 and was significant when p the Subjects ingested processed Cynanchum bungei Decne equated to less than 5%. powder (100%). I0127. Moreover, when a subject gave consent, pictures 0113 9. The Huangjiu group: the subjects ingested Hua were taken using a camera (MZ50) under same lighting con ngjiu. ditions. 0114 10, The Longan seed group: the Subjects ingested I0128. Furthermore, some subject's hair was cut at a length dry Longan seed powder (100%). of 20 mm. (However, out of respect for the dignity of the 0115 11. The processed Longan seed group: the subjects individual subjects, the hair of those individuals who wished ingested processed Longan seed powder (100%). for their hair not to be cut was compared to their usual hair 011 6 12, The “compound ingredients 1” group: the sub style to monitor any changes in hair growth.) jects ingested the "compound ingredients 2' powder which consisted of the processed semi-mature Soybean and the pro Time Points of Evaluation cessed Polygoni Multiflori Radix at a ratio of 2.5:1.0 (w:w) I0129. Data was collected and evaluated at the following respectively. times: before the test, at the end of the 6th week and again at 0117 13, The “compound ingredients 2 group: the sub the end of the 12th week. However, in the following descrip jects ingested the "compound ingredients 2' powder which tion, the data gathered before the test and that gathered at the consisted of powders of the processed semi-mature soybean end of the 12th week was used. and the processed Cynanchum bungei Decne with a ratio of 2.5:1.0 (w:w) respectively. Results 0118 14, The “compound ingredients 3 group: the sub 0.130 FIG. 1 shows the results for the alopecia and areas of jects ingested the "compound ingredients 3' which consisted thinning hair. In the cases when the raw yellow soybeans, the of powders of processed semi-mature Soybeans, processed mature yellow soybeans, the Huangjiu, the raw Polygoni Polygoni Multiflori Radix and Longan seeds with a ratio of Multiflori Radix and the raw Cynanchum bungei Decne were 12.5:5:1 (w:w:w) respectively. taken respectively, no improvement of the alopecia and/or areas of thinning hair was observed. These results show that Dosage and Frequency there was no hair restorative effect when these materials were 0119 The raw yellow soybean powder, the processed taken respectively. semi-mature soybean powder, the mature yellow soybean I0131. In addition, in those cases when the processed semi powder and the boiled black soybean powder were taken mature Soybean, the boiled black Soybean, the processed twice a day—once before breakfast and again once before Polygoni Multiflori Radix, the processed Cynanchum bungei retiring at night-time, with a dosage of 8 g each time, ingest Decne, Longan seeds or the processed Longan seeds were ing a total of 16 g per day. taken respectively, little improvement in the alopecia and/or US 2009/01 04295 A1 Apr. 23, 2009

areas of thinning hair was found. However, there were no Huangjiu also has a history of 3000 years or more as a kind of significant changes in the statistics (each pa0.05, FIG. 1). On beverage in China, and in Japan a history of over 200 years. It the other hand, these results showed that these ingredients do has been proven that drinking Huangjiu in appropriate quan have some effect of hair restoration when taken respectively. tities positively influences one's health. The processed 0132 Also, in those cases when the “compound ingredi Polygoni Multiflori Radix and the processed Cynanchum ents 1’, the “compound ingredients 2 and the “compound bungei Decne have 1000 years or more history and were used ingredients 3' were taken respectively, significant improve as "Buyiyao' (meaning herbal tonics, a term of traditional ments in the alopecia and/or areas of thinning hair were Chinese Medicine), without any documented side effects. In found. This could not be verified when taking the ingredients recent years, the effect of processed Polygoni Multiflori independently as was the case with groups 2, 4, 6, 8, 9 and 10. Radix in decreasing serum cholesterol was found, and it is 0.133 Demonstrating the synergistic effects of ingredients also widely used for the treatment and prevention of geriatric used in combination to promote hair restoration, adding to diseases. The Ministry of Health and Welfare in Japan has significant changes in the statistics (each p-0.05, FIG. 1). also acknowledged the medicinal of the plant and has 0134 FIG. 2 is photographic data of a subject who took included it in the “Japanese Pharmacopeia’, authorizing it as “compound ingredients 1’, proving that this set of ingredients an oriental medicine in Japan. 1 had an excellent effect on hair growth (the Hatsumou). 0144. Data is not shown in this description, however in 0135 FIG. 3 is photographic data of a subject who regards to Some of the Subjects who ingested the "compound ingested “compound ingredients 2', proving that this particu ingredients 1’, the “compound ingredients 2' or the “com lar combination also had an excellent effect on hair growth pound ingredients 3', their blood-, hepatic- and kidney func (the Hatsumou). tion were examined. The results concluded that there were no 0.136 FIG. 4 is photographic data of a subject who took side effects at all. In one group of the Subjects, the values in “compound ingredients 3”. This individual participated in their data became more normal. Therefore, it has been proven this test for the sake of improving his thinning and greying that the compound ingredients are safe for ingestion. hair. After taking “compound ingredients 3' for 12 weeks, his (0145 Based on the above results, it became clear that the thinning hair improved in density and more than half of his “compound ingredients 1’, the "compound ingredients 2 gray hair turned black. These effects were based on mixing and the “compound ingredients 3' have excellent effects on Longan seeds with the “compound ingredients 1' or "com hair growth, can notably stimulate hair growth in a short pound ingredients 2. period of time, and that each compound is safe for consump 0137 Moreover, Area 1 and Area 2 had already experi tion. In addition, it can be said that the compounds of this enced hair loss about 25 years ago. The Hatsumou could be invention have the added value that is not inherent in conven confirmed even in these two areas thereby proving that “com tional hair tonics, namely that it can be processed into the pound ingredients 3” had an excellent effect on hair growth. form of delicious foods whilst having excellent hair growth 0138 FIG. 5 shows the changes in pain sensation at the effects. hair root. In those cases where the hair restoration ingredients were taken independently, no changes in pain at the hair root INDUSTRIAL APPLICABILITY were found when the hair was pulled. Additionally, in those 0146 The agent for hair growth of this invention can be cases where "compound ingredients 1', 'compound ingredi used as a medicine by an untouched mode as well as a food ents 2' or “compound ingredients 3' were taken respectively, and beverage additive. Furthermore, the agent can be pre the pain in the hair root became more perceptible. served under room temperature for a moderate to long period 0.139. In alopecia and the thinning of hair, it is well-known of time (from half a year to 2 years). The raw materials can be to be accompanied by shrinkage of the hair root. Current hair procured from regular markets, thereby ensuring its industrial tonics aim to mainly promote the circulation of blood and applicability. replenish nourishment however no reports have been found 1. An agent for hair growth characterized by comprising: documenting pain in the hair root. a processed semi-mature Soybean and/or a processed semi 0140. This inventor found that a person with alopecia or mature soybean extracts and thinning of hair either does not feel pain/or experiences only at least one Substance selected from the group consisting of slight pain when his/her hair is pulled. The inventor thought a processed Polygoni Multiflori Radix, processed that this phenomenon can be used as an evaluation index of Polygoni Multiflori Radix extracts, a processed Cynan hair growth. By taking the agent for hair growth of this inven chum bungei Decne and processed Cynanchum bungei tion, the pain at the hair root became perceptible. The reasons Decne extracts as active ingredients, for this are thought to be that the agent for hair growth of this wherein the processed semi-mature Soybean is obtained by invention either improved the health of the hair and its root, or heating soybeans within the temperature range that that the nervous function of the hair root was improved. removes the typical of raw soybean taste without pull 0141 Additionally, though it does not present in this Verizing the Soybeans by excessive heating and description as data, all the Subjects of groups 12, 13 and 14 the processed Polygoni Multiflori Radix or the processed experienced notable improvement in the sheen of hair. Cynanchum bungei Decne are each obtained by soaking 0142 Moreover, in this description, the results at the time black Soybean extracts and liquors into raw Polygoni of the 12th week were used. It is thought that further effects of Multiflori Radix or raw Cynanchum bungei Decne. hair restoration will appearby continuing this test. 2. The agent for hair growth according to claim 1, which 0143 Furthermore, at no time during which the com comprises pounds were taken were any side effects observed. Come to 'a' parts by weight of the processed semi-mature Soybean think of it, soybeans (yellow soybeans and black soybeans) and “b’ parts by weight of the processed semi-mature have a long history in their use as food—such as Natto and soybean extracts (wherein “a” and “bare numbers that bean curd in Japan—thereby clearly proving their safety. are not less than 0, and fill a relation of a+b=100) with US 2009/01 04295 A1 Apr. 23, 2009 24

& G.c' parts by weight of the processed Polygoni Multiflori Multiflori Radix extracts, “e' parts by weight of the Radix, “d parts by weight of the processed Polygoni processed Cynanchum bungei Decne and “f parts by Multiflori Radix extracts, “e' parts by weight of the weight of the processed Cynanchum bungei Decne processed Cynanchum bungei Decne and “f parts by extracts (wherein “c”, “d”, “e', and “fare numbers that weight of the processed Cynanchum bungei Decne are not less than 0, and fill a relation of 3sc+d+e+ extracts (wherein “c”, “d”, “e', and “fare numbers that fa100) with are not less than 0, and fill a relation of 3sc+d+e+ “g parts by weight of the Longan seed and “h” parts by fs 100). weight of the Longan seed extracts (wherein'g' and “f are numbers that are not less than 0, and fill a relation of 3. The agent for hair growth according to claim 1, which 22g+he30). further comprises Longan seed and/or Longan seed extracts 5. The agent for hair growth according to claim 1, which is as active ingredients. prepared as an oral type. 4. The agent for hair growth according to claim 3, which 6. The agent for hair growth according to claim 2, which is comprises prepared as an oral type. a parts by weight of the processed semi-mature soybean 7. The agent for hair growth according to claim3, which is and “b’ parts by weight of the processed semi-mature prepared as an oral type. soybean extracts (wherein “a” and “b' are numbers that 8. The agent for hair growth according to claim 4, which is are not less than 0, and fill a relation of a+b=100) and prepared as an oral type. & G.c' parts by weight of the processed Polygoni Multiflori Radix, “d parts by weight of the processed Polygoni c c c c c