לרגל חגיגות שנת ה־Celebrating the 70th birthday 70 למדינת ישראל of the State of Israel Session 3 | Chemistry and the Science of Materials 19:30–15:30 האקדמיה הלאומית הישראלית למדעים The Israel Academy of Sciences and Humanities 03 מתכבדת להזמינכם לכינוס בנושא cordially invites you to a conference on Chair: Helmut Schwarz, Alexander von Humboldt Foundation Dan Shechtman, 2011 Nobel Laureate in Chemistry; IASH member; Technion – Israel Institute of Technology June 3–7 Quasi-periodic materials discovery – The role of TEM The Grand Challenges in Gabor Somorjai, University of California, Berkeley Interface materials on the nanoscale. Dominant media of chemical change and evolution the Chemical Sciences Chair: David Milstein, IASH member; Weizmann Institute of Science 2018 Omar Yaghi, University of California, Berkeley בימים ראשון—חמישי, כ׳—כ"ד בסיוון תשע"ח Sunday–Thursday, June 3–7, 2018 Reticular chemistry 3—7 ביוני 2018 בבית האקדמיה ,At the Academy, Albert Einstein Square Makoto Fujita, The University of Tokyo כיכר אלברט איינשטיין רח' ז'בוטינסקי 43, ירושלים Jabotinsky Street, Jerusalem 43

Self-assembly goes far beyond ועדה מארגנת: פרופ' רפאל לוין )יו"ר(, פרופ' איתמר וילנר, ,(Organizing Committee: Prof. Raphael Levine (Chair Ira Weinstock, Ben-Gurion University of the Negev פרופ' יהושע יורטנר ופרופ' דן שכטמן Prof. Joshua Jortner, Prof. Dan Shechtman, Prof. Itamar Willner Structure and reactivity at the interface between molecules and solid-state materials Sunday, June 3, 2018 18:00–21:00 Reception and Opening Lecture Tuesday, June 5, 2018 Chair: Zehev Tadmor, IASH member; Technion – Israel Institute of Technology 10:00–12:15 Session 4 | Nano – Science and Molecular Machines Opening remarks Nili Cohen, President, The Israel Academy of Sciences and Humanities (IASH) 04 Raphael Levine, IASH member; The Hebrew University of Jerusalem Chair: Reshef Tenne, IASH member; Weizmann Institute of Science Evening Lecture Joshua Jortner, IASH member; University Rudy Marcus, 1992 Nobel Laureate in Chemistry; California Institute of Technology Chemistry in Israel A shot of theory at a biomolecular machine A short film: A Journey - Unfinished Sir Fraser Stoddart, 2016 Nobel Laureate in Chemistry; Northwestern University The rise and promise of artificial molecular machines based on the Monday, June 4, 2018 mechanical bond Takuzo Aida, Riken Center for Emergent Science ; The University of Tokyo 9:45–10:00 Greetings: Semibiological robotic nanocarriers responsive to endogenous signals 01 Nili Cohen, President, The Israel Academy of Sciences and Humanities (IASH) Coffee break 10:00–11:45 Session 1 | Drug Discovery 05 12:30–13:45 Session 5 | Soft Matter Chair: Michael Sela, IASH member; Weizmann Institute of Science Chair: Avinoam Ben Shaul, The Hebrew University of Jerusalem , The Scripps Research Institute Oleg Gang, Columbia University; Brookhaven National Laboratory The chemistry of large numbers Programmable nano-systems: form designed architectures to controllable processes

Ruth Arnon, IASH member; Weizmann Institute of Science Jacob Klein, IASH member; Weizmann Institute of Science Copaxone: From laboratory polymer to clinical use Hydration forces, biolubrication and gene regulation: The challenge of osteoarthritis Coffee break Lunch 02 12:00–14:15 Session 2 | Chemical & Biochemical Design 06 14:45–16:45 Session 6 | Chemistry of the Extremes Chair: Raphael Mechoulam, IASH member; The Hebrew University of Jerusalem Chair: Nir Davidson, Weizmann Institute of Science

George Whitesides, Harvard University Ferenc Krausz, Ludwig Maximilian University, Munich; Max Planck Institute of Quantum Optics, Garching Molecular recognition in water is different. The hydrophobic effect, and enthalpy/entropy Attosecond physics: from basic research to real-world applications

compensation Albert Stolow, University of Ottawa; National Research Council Canada Frances Arnold, California Institute of Technology Transition states in the excited state: Dynamics at conical intersections Engineering by evolution: Bringing new chemistry to life Edvardas Narevicius, Weizmann Institute of Science Arieh Warshel, 2013 Nobel Laureate in Chemistry; University of Southern California Cold chemistry with cold molecules Progress and challenges in rational computer – aided enzyme design Coffee break Lunch 11 16:00–18:15 Session 11 | Photosynthesis and Energy Storage Chair: Yaron Silberberg, IASH member; Weizmann Institute of Science Shaul Mukamel, University of California, Irvine 07 17:00–19:30 Session 7 | Chemistry on Large Scales Novel spectroscopic probes of photosynthetic charge and energy transfer with Chemistry of our environment quantum and x-ray light Chair: Ronnie Ellenblum, IASH member; The Hebrew University of Jerusalem Paul Brumer, University of Toronto Seeking quantum effects in biological light-harvesting systems Geraldine Richmond, University of Oregon Understanding complex liquid interfaces of environmental importance Nathan Nelson, Photosynthetic reaction centers: The engine of life Mark Thiemens, University of California, San Diego Greg Engel, The use of isotope effects to understand atmospheres and climates present and past and Design principles of photosynthetic light harvesting track the origin of life Coffee break Chemistry of the cosmos 18:30 Evening Lecture Chair: Hagai Netzer, Tel Aviv University Chair: Moti Segev, IASH member; Technion – Israel Institute of Technology

Amiel Sternberg, Tel Aviv University; Max Planck Institute for Extraterrestrial Physics Munich; Center for Dan Shechtman, 2011 Nobel Laureate in Chemistry; IASH member; Technion – Israel Institute of Technology Computational Astrophysics Flatiron Institute Simons Foundation, New York City Scientific blunders Cosmic chemistry: From simplicity to complexity Thursday, June 7, 2018 Wednesday, June 6, 2018 12 10:00–11:45 Session 12 | System Chemistry 10:00–11:45 Session 8 | Quantum Technologies Chair: Yitzhak Apeloig, Technion – Israel Institute of Technology 08 Xiaoliang Sunney Xie, Harvard University Chair: Paul Weiss, University of California, Los Angeles Single cell genomics: When stochasticity meets precision Dorit Aharonov, The Hebrew University of Jerusalem James Heath, Institute for Systems Biology in Seattle Quantum Physics through the computational lens A molecular view of immuno-oncology Moti Segev, IASH member; Technion – Israel Institute of Technology Coffee break Topological photonics 12:00–14:00 Session 13 | Imaging on the Molecular and Atomic Scale , IASH member; Tel Aviv University 13 Molecular electronics and plasmonics: Electrons, light and heat transport at the nanoscale Chair: Dan Shechtman, 2011 Nobel Laureate in Chemistry; IASH member; Technion – Israel Institute of Lunch Technology 13:00–14:15 Session 9 | Big Data / Machine Learning and Deep Learning Knut Urban, Helmholtz Research Center, Juelich 09 Aberration-corrected electron microscopy: Probing physics and chemistry of Chair: David Harel, Vice President, IASH; Weizmann Institute of Science matter in atomic dimensions Naftali Tishby, The Hebrew University of Jerusalem Wah Chiu, Stanford University The machine & deep learning revolution: How does it change our understating of Cryo-EM, an imaging tool beyond crystallography chemical sciences? Shimon Weiss, Bar-Ilan University Todd Martinez, Stanford University Dynamic structural biology: Two decades of smFRET applied to transcription initiation How much chemistry can we learn with machine learning? Lunch Coffee break 14 14:45–17:30 Session 14 | Chemistry of Life 14:15–16:00 Session 10 | Computational & Theoretical 10 Chair: Raphael Levine, IASH member; The Hebrew University of Jerusalem Chair: Rudy Marcus, 1992 Nobel Laureate in Chemistry; California Institute of Technology William Schopf, University of California, Los Angeles EKU Gross, Max Planck Institute of Microstructure Physics; The Hebrew University of Jerusalem Earth's oldest fossils: Primordial life evolved early, far and fast TDDFT: Simulating, analyzing and controlling many-electron dynamics, from photovoltaics Roger Kornberg, 2006 Nobel Laureate in Chemistry; Stanford University to laser-driven spin switching The end of disease? Leeor Kronik, Weizmann Institute of Science , 2009 Nobel Laureate in Chemistry; IASH member; Weizmann Institute of Science Progress and challenges in the formalism and application of density functional theory The origin of life, or: What came first the genetic code or its products? Leticia González, University of Vienna Closing: Nili Cohen, President, IASH Molecular photochemistry Please confirm participation to Ms. Aviva Levy נא לאשר השתתפות לגב' אביבה לוי [email protected] [email protected] On-street parking is generally available in the vicinity מספר המקומות באולם מוגבל. הכניסה על בסיס מקום פנוי. חניה ציבורית .of the Academy ברחובות הסמוכים לאקדמיה.