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2 OUR PROMISE

4 ANTIOXIDANT AUTHORITY

6 PRODUCT LINE

7 SKIN TYPES AND CONDITIONS

9 CLEANSE & TONE

19 PREVENT

29 CORRECT

43 MOISTURIZE

51 PROTECT

59 SKIN SYSTEMS

65 BODY CORRECT THE SKINCEUTICALS PROMISE

INNOVATION & ANTIOXIDANTS 1997 SkinCeuticals is founded based on academic research by Dr. Sheldon Our mission is to improve skin health. Pinnell. Dr. Pinnell established and patented the first formulation parameters required for vitamin C absorption and efficacy in skin. Dedicated to this purpose, we make one simple promise — He and the SkinCeuticals research team helped pioneer the advent of cosmeceuticals with the original topical vitamin C formula. These provide advanced skincare backed by science. parameters came to be known as the Duke parameters, guiding new antioxidant development.

ADVANCED SKINCARE — PREVENTION, PROTECTION, AND CORRECTION PRODUCT DEVELOPMENT C E FERULIC® 2005 SkinCeuticals adds ferulic acid to vitamins C and E, resulting in To maintain and improve skin health, an effective skincare At SkinCeuticals the products start with the science. unmatched environmental protection and becoming the new standard in regimen must contain three fundamental elements — SkinCeuticals helped pioneer the advent of cosmeceuticals antioxidant technology. prevention, protection, and correction. Our line of advanced and has continued to lead the industry as one of the skincare products is designed to prevent future damage, protect first companies to provide scientific evidence to support healthy skin, and correct previous damage. At SkinCeuticals, product benefits. achieving results means not only restoring youthful, radiant 2008 PHLORETIN CF® skin — it means preventing serious skin conditions. Today, SkinCeuticals has formed networks with top scientists After extensive research, SkinCeuticals identifies a powerful molecule, from the fields of cellular and molecular biology, chemistry, phloretin, which works synergistically with vitamin C and ferulic acid to Founded in 1997, SkinCeuticals discovers, develops, and biophysics, and medicine to further our understanding of provide broad-range antioxidant protection. delivers innovative dermatology products that improve the the processes of skin aging, photoaging, and other individual overall health and appearance of the skin. We use pure, skin conditions. Over the years, our research team has earned pharmaceutical-grade ingredients at optimal concentrations numerous federal and state grants to help further the pursuit with proven scientific results to elegantly craft functional of technologies to deepen our knowledge of the skin and PHLORETIN CF® GEL & AOX+® EYE GEL products. Our integrated skincare program works as a skin health. 2011 SkinCeuticals develops a serum-in-a-gel technology, revolutionizing complete system for long-lasting comprehensive results. the texture of SkinCeuticals topical antioxidants while maintaining the Through research, innovation, education, and media integrity and efficacy of the original serum formula. Our dedication to developing advanced skincare backed by relations, SkinCeuticals constantly strives to promote and science has earned us a strong reputation with the medical improve skin health. community worldwide. Dermatologists, plastic surgeons, medi-spas, and other skincare professionals trust SkinCeuticals RESVERATROL B E to promote skin health — not trends. 2014 SkinCeuticals introduces its first antioxidant night concentrate to help repair and prevent accumulated damage by boosting skin's own antioxidant defense system. 2 3 The patented Duke parameters ensure effective delivery of vitamin C in skin: 1 Pure I-ascorbic acid. 3 Vitamin C derivatives do ANTIOXIDANT not increase vitamin C A concentration between levels in skin. 10-20%. A concentration outside AUTHORITY this range does not provide 2 meaningful levels of vitamin C. One of the most essential and well studied Formulated at an antioxidants is vitamin C. acidic pH. At a pH above 3.5, vitamin Not all vitamin C is the same. C does not penetrate skin effectively.

Antioxidants neutralize environmental assaults that can cause fine lines, wrinkles, discolorations, and serious skin conditions.

Synergistic antioxidant combinations can provide up to 8x skin’s natural environmental protection.

4 5 SKINCEUTICALS PRODUCT LINE SKIN TYPES SKIN CONDITIONS

Normal Skin Aging Normal skin has an ideal balance of oil and hydration levels. Skin aging is a degenerative process caused by intrinsic, Therefore skin is neither greasy nor dry. Most SkinCeuticals chronological aging, and extrinsic, environmental aging. products are appropriate for use on this skin type. Both intrinsic and extrinsic aging contribute to problems in the dermis and the epidermis leading to slower cell turnover Oily Skin and breakdown of collagen and elastin fibers. Visible signs of Includes conditions associated with excess oils and congested aging include a loss of skin’s radiance and firmness, as well as pores. Products recommended for this skin type help minimize wrinkles, laxity, and uneven pigmentation. oiliness and congestion as they protect skin and help prevent further damage. Acne Acne is caused by excess sebum production and inefficient Dry Skin desquamation. Typical acne-related lesions include com- Includes conditions associated with scaling, itching, flaking, edones, papules, pustules, and nodes or cysts. While the and burning, and is often an inherited skin condition. Products cause of acne is unknown, hormones and stress are contrib- recommended for this skin type help counter moisture loss, uting factors. improve elasticity, and rejuvenate dull skin. Hyperpigmentation Combination Skin Excess and uneven distribution of melanin, the natural Includes combinations of oily and dry skin; product pigment that gives color to skin, can be exacerbated due to recommendations may vary depending on where skin fits UV exposure, hormonal fluctuations, or trauma to the skin, within this range. causing uneven skin tone and brown spots. Sensitive Skin Rosacea Includes conditions such as rosacea, seborrheic dermatitis, Rosacea is a common skin disorder characterized by flare- and atopy; sensitivity can be inherited or acquired. Sensitive ups of redness and flushing. Over time redness can become skin exhibits inflammatory responses to various triggers such more constant and bumps and pimples may develop. This as allergens, preservatives, or fragrances. Suggested products condition transcends skin types. will help soothe skin. Dehydrated Dehydration occurs due to a lack of moisture in the skin. Indications of dehydrated skin can include itching, tight, and dull-looking skin. Once the skin becomes dehydrated it can no longer carry out its barrier role.

Sensitized Sensitivity is common after procedures such as micro- dermabrasion, laser resurfacing, or peels, as well as in peri- menopausal or mature skin. Skin sensitivity can be associated

6 with dehydrated, traumatized, aging, or delicate skin. 7 CLEANSE & TONE

Formulated to meet the exacting standards of skincare professionals, SkinCeuticals and toners include a variety of active ingredients such as hydroxy acids, botanical extracts, and cleansing agents to lift impurities and oils, gently exfoliate dead skin cells, and balance pH levels. Our cleansing and toning products leave the skin feeling fresh and clean without increased dryness or oiliness.

9 AGING ACNE HYPER- ROSACEA DEHYDRATED SENSITIZED DESCRIPTION AGING ACNE HYPER- ROSACEA DEHYDRATED SENSITIZED DESCRIPTION Roughness| Dullness PIGMENTATION Roughness| Dullness PIGMENTATION

LHA Cleansing Gel Exfoliating gel to decongest pores, Foaming Cleanser Lightweight cleanser with smooth skin texture, and brighten skin gentle foaming agents to remove O C N O D C S LHA, glycolic, and salicylic acids surface debris Page 12 Page 14 Soap-free cleanser and botanical extracts

Clarifying Cleanser Salicylic acid exfoliating cream Gentle Cleanser Removes impurities and excess oil, cleanser for skin prone to breakouts while soothing and calming dry O C N O D C S Microbeads and salicylic, glycolic, and or sensitive skin Page 12 mandelic acids Page 15 Orange oil and gentle skin conditioners

Micro-Exfoliating Scrub Gel scrub with microbeads to smooth LHA Solution Exfoliating removes excess residue and polish skin and surface cells to decongest pores N O D C O C Physical-exfoliation microbeads and LHA, glycolic, and salicylic acids Page 13 aloe barbadensis Page 15

Simply Clean Pore-refining gel to cleanse, exfoliate, and Conditioning Solution Exfoliating and conditioning toner with soothe normal, combination, or oily skin hydroxy acids to remove impurities N O D C N D C Fruit acid blend and botanicals of chamomile Glycolic and salicylic acids and Page 13 and aloe barbadensis Page 16 eucalyptus oil

Purifying Cleanser Conditioning gel with glycolic acid to Equalizing Toner Fragrance-free and alcohol-free toner remove impurities to gently remove excess residue N O C N O D C S Glycolic acid and glycerin Glycolic acid, glycerin, and botanical extracts Page 14 Page 16

SKIN TYPES: N = Normal O = Oily D = Dry C = Combination S = Sensitive SKIN TYPES: N = Normal O = Oily D = Dry C = Combination S = Sensitive For optimal results, please consult with your physician. For optimal results, please consult with your physician. LHA CLEANSING GEL MICRO-EXFOLIATING SCRUB

Designed for aging skin, LHA Cleansing Gel combines potent cleansing agents with LHA, Designed for congested and rough skin, this mild exfoliating gel combines natural microbeads glycolic acid, and salicylic acid to decongest pores, smooth irregularities, and brighten skin. with gentle cleansing and hydrating agents to thoroughly cleanse pores and promote healthy Additionally, the triple combination of exfoliating agents works in concert with LHA Solution cell renewal without damaging or drying skin. Physical-exfoliation earth microbeads are and Blemish + Age Defense to prime skin for clinical procedures and professional treatments by formulated at optimized density to provide intense and even exfoliation without causing initiating the exfoliation process to enhance penetration of peeling agents. lacerations. Additionally, a high purity of aloe softens polished skin. Designed for all skin types, this scrub is safe for use on face and body. BENEFITS • LHA provides precise and even exfoliation to unclog pores while diminishing surface indicators BENEFITS of age including discolorations, fine lines, wrinkles, and rough texture • Natural microbeads gently exfoliate and polish away dead surface cells • Glycolic acid accelerates the natural cell renewal process to improve skin tone and texture • Glycerin and aloe soften, moisturize, and smooth skin • Salicylic acid unclogs pores and removes dirt, oil, and other debris that lead to breakouts • Ideal for all skin types • Gentle cleansing agents remove excess oils and makeup • Ideal for oily and combination skin types

CLARIFYING CLEANSER SIMPLY CLEAN

Specifically formulated for acne-prone skin, SkinCeuticals Clarifying Cleanser combines Ideal for combination or oily skin, this skin-refining gel cleanser combines an exfoliating salicylic acid, an FDA approved acne treatment, with the exfoliating powers of glycolic and hydroxy acid blend with botanical extracts to gently remove impurities, excess oils, and mandelic acids to unclog pores and help improve the appearance of damaged skin. Along with makeup, and prepare skin for epidermal peeling. Also contains botanical extracts of chamomile these powerful alpha and beta hydroxy acid ingredients, the cleanser also includes smoothly and aloe to help soothe skin. rounded microbeads to gently slough off dead skin cells and cellular debris. Used in conjunction with SkinCeuticals Blemish + Age Defense, this cleanser treats existing whiteheads, blackheads, BENEFITS and other acne-related blemishes while helping to prevent future acne breakouts. • Gently exfoliates dead skin cells • Clarifies the skin and smoothes out rough texture BENEFITS • Removes excess surface oils and makeup • 2% salicylic acid clears acne blemishes • Ideal for all skin types • Smooth polyethylene beads remove loosened skin cells without lacerating skin • Mild soaps in a creamy base ensure effective cleansing without over drying or irritating the skin • Helps break up the cohesion of keratinized skin cells to speed up the natural exfoliation process and allow fresh, new skin to appear • Ideal for oily and acneic skin types

12 13 PURIFYING CLEANSER GENTLE CLEANSER

Suitable for most skin types, Purifying Cleanser removes resistant surface debris and impurities This mild cream cleanser removes impurities and excess oils without drying the skin. Gentle to leave skin fresh and conditioned. The addition of glycolic acid provides gentle exfoliation to enough to be used several times daily, this non-irritating cleanser conditions, soothes, and calms improve skin tone and texture and prepare skin for epidermal peeling, while glycerin provides sensitive or traumatized skin. added moisturization to condition skin. This light gel is designed with a pH close to that of skin

to thoroughly cleanse without stripping the barrier. BENEFITS • Non-irritating BENEFITS • Contains emollients and skin conditioning ingredients • Mild foaming and cleansing action dissolves dirt and oil particles on skin’s surface • Soothing and calming for sensitive or traumatized skin • Glycolic acid gently exfoliates to improve skin tone and texture • Ideal following skin rejuvenating procedures • Glycerin softens and smoothes skin • Ideal for normal, oily, and combination skin types

FOAMING CLEANSER LHA SOLUTION

This lightweight cleanser for all skin types deeply cleanses pores, removes excess surface Designed for aging skin, LHA Solution is formulated with a triple combination of exfoliating oils, and clears surface impurities, leaving the skin feeling completely refreshed. Mild and agents to efficiently remove excess residue and surface cells to decongest pores. This low pH non-drying, this fragrance-free cleanser contains gentle, non-allergenic ingredients to prevent combination of LHA, glycolic acid, and salicylic acid also works in concert with LHA Cleansing irritation. Perfect for removing makeup and preparing the skin for SkinCeuticals treatments. Gel and Blemish + Age Defense to prime skin for clinical procedures and professional treatments by initiating the exfoliation process to enhance penetration of peeling agents. BENEFITS • Non-irritating BENEFITS • Removes excess surface oils without causing dryness • LHA provides precise and even exfoliation to unclog pores while diminishing surface indicators • Perfect for removing makeup of age including discolorations, fine lines, wrinkles, and rough texture • Ideal for all skin types • Glycolic acid accelerates the natural cell renewal process to improve skin tone and texture • Salicylic acid unclogs pores and removes dirt, oil, and other cellular debris • Ideal for oily and combination skin types

14 15 CONDITIONING SOLUTION

Designed for normal or combination skin, this exfoliating toner removes excess residue while improving skin tone and texture. Conditioning Solution combines alpha and beta hydroxy acids with denatured alcohol to prime skin and minimize the appearance of pores, while eucalyptus oil leaves skin fresh and purified. Formulated at a low pH, this hydroxy acid toner is ideal for preparing skin for clinical procedures and professional treatments.

BENEFITS • Freshens and decongests skin while minimizing the appearance of pores • Optimized delivery system for targeted exfoliation • Mild formulation with a pH lower than the skin’s natural acid mantle safely prepares skin for professional treatments • Ideal for normal, dry, and combination skin types

EQUALIZING TONER

Optimal for all skin types, Equalizing Toner helps balance, refresh, and restore the skin’s protective pH mantle while removing residue. Mixed hydroxy acids in this fragrance-free and alchohol-free toner help gently exfoliate dead skin cells while botanical extracts such as witch hazel, rosemary, aloe, and chamomile soften, soothe, and tone the skin.

BENEFITS

• Gently exfoliates dead skin cells • Helps restore the skin’s protective pH mantle • Soothes and tones skin • Ideal for all skin types

16 17 PREVENT

Research shows that aging skin is the result of more than just years on the calendar. Exposure to environmental elements like sunlight, smoke, and air pollution causes premature aging in skin. Not only does this lead to the formation of lines, wrinkles, and discoloration – it can lead to more serious skin conditions. Sunscreens, an essential first line of defense, only block up to 55% of damaging free radicals that cause chemical reactions in skin.* Studies prove antioxidants effectively neutralize chemical reactions generated when skin is exposed to environmental assaults.

A comprehensive skincare program can help prevent environmental damage as well as the onset of more serious skin conditions. When used together, a topical vitamin C antioxidant serum and broad-spectrum sunscreen provide advanced protection against UV-, Infrared Radiation A-, and pollution-induced aging and skin damage. Working in synergy, topical vitamin C serums (using pure l-ascorbic acid) help prevent environmental aggressors, while Resveratrol B E boosts skin’s own antioxidant defense system to repair and prevent accumulated damage. These antioxidants help protect from environmental aggressors and promote natural repair from the inside for comprehensive environmental protection and outside correction.

*Haywood, R. et al (2006). J Invest Dermatol 121:862-868

19 AGING ACNE HYPER- ROSACEA DEHYDRATED SENSITIZED Wrinkles | Laxity PIGMENTATION DESCRIPTION C E Ferulic® Delivers advanced environmental ® protection while reducing fine lines C E FERULIC N D S and wrinkles 15% vitamin C, 1% vitamin E, C E Ferulic is a revolutionary antioxidant combination that delivers advanced environmental Page 21 and 0.5% ferulic acid protection against UVA, UVB, IRA, and pollution by neutralizing free radicals that cause Phloretin CF® Delivers advanced environmental accelerated skin aging. By providing powerful antioxidant protection, C E Ferulic helps prevent protection while diminishing N C O premature collagen breakdown and replenish lipids for a diminished appearance of fine lines and discoloration 2% phloretin, 10% vitamin C, wrinkles. Containing 15% pure vitamin C (l-ascorbic acid), 1% vitamin E (alpha-tocopherol), Page 22 and 0.5% ferulic acid and ferulic acid, this super-antioxidant combination offers 8x skin’s natural environmental protection. Phloretin CF® Gel Delivers advanced environmental protection while diminishing N O C BENEFITS discoloration 2% phloretin, 10% vitamin C, • Provides advanced environmental protection against damaging free radicals induced by UV, Page 23 and 0.5% ferulic acid IRA, and pollution Resveratrol B E Helps repair and prevent accumulated • Increases firmness and reduces the appearance of wrinkles damage for improved radiance and N D C density 1% pure resveratrol, 0.5% baicalin, • Lipid serum texture ideal for dry, cold climates Page 24 1% vitamin E • Excellent complement to sunscreen for enhanced protection

® • Tested suitable for post-laser skin (non-ablative and ablative fractional). Always consult with AOX+ Eye Gel Protects against environmental damage, reduces puffiness and signs of fatigue a physician for individual post-procedure care N O D C 1% phloretin, 5% vitamin C, 0.5% • Ideal for normal, dry, and sensitized skin types Page 25 ferulic acid, ruscus aculeatus, and caffeine

C + AHA Two-in-one treatment for environmental protection N O C and exfoliation

Page 26 15% vitamin C and 10% hydroxy acids 10

Serum 20 AOX+ Delivers the maximum amount 8 of pure vitamin C to the skin N O C This graph shows enhanced levels of antioxidant for environmental protection 6 protection provided when combining ferulic acid Page 26 20% vitamin C, 0.2% ferulic acid with vitamins C and E. The combination provides 8x 4 protection compared to 4x protection provided by Serum 15 AOX+ Environmental protection for all vitamins C and E together and 2x protection provided ® skin types 2 by vitamin C or E alone. Phloretin CF and N O D C ® 15% vitamin C, 0.2% ferulic acid PROTECTION ANTIOXIANT Phloretin CF Gel provide equally powerful environmental protection. Page 27 0 Vehicle Vitamin C Vitamin E C+E+ Ferulic Acid Serum 10 AOX+ Introductory treatment for environmental protection N O D C S 10% vitamin C, 0.2% ferulic acid Page 27 All SkinCeuticals antioxidants neutralize free radicals, defend against environmental damage, and help prevent premature signs of aging SKIN TYPES: N = Normal O = Oily D = Dry C = Combination S = Sensitive For optimal results, please consult with your physician. 21 PHLORETIN CF® PHLORETIN CF® GEL

Phloretin CF is a powerful antioxidant that combines a patented combination of 2% phloretin, This revolutionary serum-in-a-gel offers the same broad-range environmental protection and 10% pure vitamin C, and 0.5% ferulic acid. Phloretin CF shields skin from damaging free proven correction as the original Phloretin CF serum in a state-of-the-art gel texture that radicals as it restores a more radiant, even complexion. In addition to broad-range environmental complies with the strict standards of the Duke antioxidant parameters for vitamin C serums. protection, this antioxidant is proven to help correct signs of existing damage by accelerating This synergistic antioxidant combines a patented blend of 2% phloretin, 10% pure vitamin C, cellular renewal to diminish discolorations and fine lines while improving skin tone and texture. and 0.5% ferulic acid for broad-range environmental protection. It is also proven to correct signs of existing damage by accelerating cellular renewal to diminish discolorations and fine BENEFITS lines while improving skin tone and texture. • Provides advanced environmental protection against damaging free radicals induced by UVA, UVB, and pollution BENEFITS • Retextures skin and evens skin tone for a firmer, brighter complexion • Provides advanced environmental protection against damaging free radicals • Diminishes dullness and discolorations induced by UVA, UVB, and pollution • Light serum texture ideal for humid, hot climates • Retextures skin and evens skin tone for a firmer, brighter complexion • Excellent complement to sunscreen for enhanced protection • Diminishes dullness and discolorations • Ideal for normal, oily, and combination skin types • Proven to be well-tolerated by men post- • Excellent complement to sunscreen for enhanced protection • Comforting light texture ideal for normal, oily, and combination skin types

100 9

90 8

80 7

70 6 60 REDUCES THYMINE DIMERS CAUSED BY UVA RADIATION 5 PROTECTS AGAINST UV-INDUCED ERYTHEMA 50 Thymine dimers are damaging mutations in skin that impair 4 UV-induced erythema is an inflammatory response 40 essential skin processes. to UV irradiation indicated by redness. PROTECTION 3 30 ® ® In vivo punch biopsy shows that Phloretin CF significantly 2 In vivo, Phloretin CF Gel provides a high level of 20 reduces thymine dimer count vs. placebo when exposed to protection against UV-induced erythema compared to MEAN NO. THYMINE DIMERS MEAN NO. 10 1 solar-simulated light. placebo when exposed to solar-simulated light. 0 0 Placebo Phloretin CF Unexposed Placebo Phloretin CF Gel (Control)

22 23 NEW

RESVERATROL B E AOX+® EYE GEL

Created especially for the delicate eye area, AOX+ Eye Gel is an innovative serum-in-a-gel A first-of-its-kind nighttime antioxidant treatment, Resveratrol B E boosts skin’s own formulation that shields skin from environmental damage while correcting the appearance of antioxidant defense system to help repair and prevent accumulated damage by neutralizing existing environmental damage and reducing the appearance of puffiness and fatigue. This triple- age-accelerating free radicals, promoting skin’s natural repair to diminish the signs of antioxidant blend featuring phloretin, pure vitamin C, and ferulic acid combats environmental accumulated damage, and strengthening functionality to resist new damage. This triple US damage and signs of fatigue around the delicate eye area, while ruscus aculeatus increases patent–pending formulation features a maximized concentration of 1% pure resveratrol, 0.5% microcirculation to reduce swelling, and caffeine helps to facilitate the drainage of excess fluid. baicalin, an antioxidant that reduces intracellular inflammation, and 1% vitamin E. This Together, this synergistic combination protects the delicate eye area from free radical damage synergistic combination provides enhanced efficacy and statistically significant improvement in radiance and density. and repairs visible signs of aging.

BENEFITS BENEFITS

• Boosts skin’s own antioxidant defense system to repair and prevent damage • Prevents premature signs of aging and corrects existing signs of environmental damage • Renews skin’s radiance and elasticity • Helps reduce the appearance of puffiness and under-eye bags • Rebuilds skin firmness and density by 18.9% • Combats signs of fatigue to restore a vibrant, rested appearance • Night serum concentrate • Ideal for all but sensitive skin types • Ideal for most skin types, including mature skin and retinoid users

COLLAGEN III

2 30

25

20

1 15 EFFECT OF AOX+ ® EYE GEL ON UNDER EYE CIRCULATION

PROMOTES ANTI-AGING CORRECTION % INCREASE 10 The Laser Doppler Perfusion Imaging System uses Collagen III is a key constituent of the extracellular matrix a low power laser to scan the surface of skin, to

FOLD CHANGE VS. BASELINE 5 and considered a structural protein responsible for density determine microcirculation by the rate of blood and firmness. flow through capillaries. 0 0 Baseline Week 12 Week 8 Week 12

24 25 C + AHA SERUMSERUM 2015 AOX

This two-in-one antioxidant treatment offers environmental protection and exfoliation in one Serum 15 neutralizes free radicals, defends against environmental damage, and helps prevent product to improve visible signs of aging skin inside and out. C + AHA combines the antioxidant signs of premature aging to restore healthy-looking skin. This lightweight, fast-absorbing serum power of 15% pure vitamin C to neutralize free radicals with the exfoliating benefits of 10% combines 15% pure vitamin C with ferulic acid to enhance antioxidant performance. Serum 15 hydroxy acids to exfoliate and smooth the skin. The dual action reduces the appearance of fine reduces the appearance of fine lines and wrinkles and restores healthy-looking skin. lines and wrinkles as it restores a smoother, more radiant complexion. BENEFITS BENEFITS • Provides advanced environmental protection • Protects against environmental damage • Helps prevent and diminish signs of premature skin aging • Reduces the appearance of fine lines and wrinkles • Reduces the appearance of fine lines and wrinkles • Removes dull, dry surface cells to reveal radiant, younger-looking skin • Ideal for all skin types, except very sensitive • Ideal for normal, oily, and combination skin types

SERUMSERUM 2020 AOX SERUMSERUM 2010 AOX

Offering the maximum concentration of pure vitamin C that can be absorbed by the skin Specifically designed for sensitive skin types or conditions, Serum 10 neutralizes free according to the Duke parameters, Serum 20 restores and protects healthy-looking skin by radicals, defends against environmental damage, and helps prevent signs of premature aging. defending against environmental damage and preventing signs of premature aging. This This lightweight, fast-absorbing serum combines 10% pure vitamin C with ferulic acid to lightweight, fast-absorbing serum combines 20% pure vitamin C with ferulic acid to enhance enhance antioxidant performance. Serum 10 reduces the appearance of fine lines and wrinkles antioxidant performance. Serum 20 reduces the appearance of fine lines and wrinkles and and restores healthy-looking skin. restores healthy-looking skin. BENEFITS BENEFITS • Provides advanced environmental protection • Provides advanced environmental protection • Helps prevent and diminish signs of premature skin aging • Helps prevent and diminish signs of premature skin aging • Reduces the appearance of fine lines and wrinkles • Reduces the appearance of fine lines and wrinkles • Ideal for all skin types, including sensitive skin • Ideal for normal, oily, and combination skin types

26 27 CORRECT

Over time, regardless of lifestyle, skin begins to change, and signs of aging may appear. Fine lines, wrinkles, discoloration, and loss of elasticity become more visible. These signs can be the result of collagen breakdown, slower cell turnover, and loss of moisture. Damage is intensified by sun exposure, environmental elements, and smoking. A strong preventive program is critical to prevent further damage from these assaults and to help slow down the aging process. SkinCeuticals corrective products combine reparative, brightening, and exfoliating ingredients to help rehabilitate damaged skin, restoring a healthier and more youthful appearance. This category also includes products formulated specifically for delicate areas such as the eyes and lips.

28 2929 AGING ACNE HYPER- ROSACEA DEHYDRATED SENSITIZED AGING ACNE HYPER- ROSACEA DEHYDRATED SENSITIZED Wrinkles | Laxity PIGMENTATION DESCRIPTION Wrinkles | Laxity PIGMENTATION DESCRIPTION A.G.E. Interrupter Visibly diminishes the effects of glycation Blemish + Age Defense Prevents the formation of acne, minimizes including creping, thinning skin blemishes, and reduces signs of aging N D C S O C Blueberry extract, proxylane, and Dioic, LHA, salicylic, glycolic, and citric acids Page 32 phytosphingosine Page 36

A.G.E. Eye Complex Reduces the appearance of dark circles, Retexturing Activator Simultaneously exfoliates and replenishes puffiness, and crow’s feet moisture for smooth, radiant skin N D C S N O D C S Blueberry extract, proxylane, complex of 25% hydroxyethyl urea/aminosulfonic acid Page 32 flavonoids and peptides, and optical diffusers Page 37 compound, kombuchka, and hyaluronic acid

Face Cream Lightweight cream to combat the visible Redness Neutralizer Reduces redness and flushing, while effects of collagen breakdown and soothing irritation and discomfort N D S N O D C S moisture loss Soy isoflavones, alpha Palmitoyl tripeptide-8, eperua falcata Page 33 tocopherol, and silymarin Page 37 bark extract, bisabolol, and glycerin

Eye Balm Rich emollient cream to rehabilitate Phyto + Hydrating botanical serum to aging skin and reduce puffiness diminish discoloration N D S N O D C S Soy isoflavones, alpha tocopherol, silymarin, Arbutin glycoside, kojic acid, and Page 33 and marine extract Page 38 thyme and cucumber extracts

Skin Firming Cream Firming repair cream to correct early Phyto Corrective Gel Soothes, calms, and hydrates sensitive, signs of environmental damage compromised, or problematic skin N O C N O D C S Centella asiatica and ectoin Thyme and cucumber extracts, botanical Page 34 Page 38 glycosides, uva ursi, and hyaluronic acid

Eye Cream Firming eye cream to help correct Clarifying Clay Masque Purifying treatment to decongest pores dark circles and early signs of aging and remove excess oil N O C N O D C S Centella asiatica, ectoin, eye-specific 5% mixed hydroxy acids, bentonite and Page 34 peptides Page 39 kaolin clays, and titanium dioxide

Retinol 0.5 Refines skin to diminish age spots, uneven Antioxidant Lip Repair Helps prevent environmental damage, tone, fine lines, and wrinkles while smoothing and refining lip surface N O D C N O D C S 0.5% retinol and bisabolol Silymarin, vitamin E, glycerin, and Page 35 Page 39 hyaluronic acid

Retinol 1.0 Refines skin to diminish age spots, Epidermal Repair Relieves redness and soothes uneven tone, fine lines, and wrinkles inflammation for sensitive and post- N O D C N O D C S procedure skin 1.0% retinol and bisabolol Beta glucan, titrated extract of centella Page 40 Page 35 asiatiaca, sodium palmitoyl proline and nymphea alba flower extract Advanced Reduces stubborn discolorations and Pigment Corrector prevents reoccurrence Biocellulose Restorative Replenishing treatment for Ellagic acid, hydroxyphenoxy propionic acid, Masque compromised skin N O D C Biocellulose fibers and sterilized water and yeast extract N O D C S Page 36 SKIN TYPES: N = Normal O = Oily D = Dry C = Combination S = Sensitive Page 40 For optimal results, please consult with your physician. For optimal results, please consult with your physician. A.G.E. INTERRUPTER FACE CREAM

A.G.E. Interrupter is a multi-action formulation for mature skin that delivers three powerful ingredients Specifically formulated to combat the visible effects of collagen breakdown and moisture loss in proven to correct visible signs of aging including wrinkles, loss of elasticity, and a crepey, thinning mature skin. This light, rehabilitative cream provides powerful firming benefits and replenishes appearance. One main cause of internal aging is glycation, which occurs when excess glucose molecules moisture with emollients – perfect for skin depleted by the ravages of time. Addresses signs of bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.) aging that result from three factors: moisture loss, collagen breakdown, and free radical damage. that lead to severe skin wrinkling. A.G.E. Interrupter helps improve elasticity and firmness caused by Face Cream contains targeted botanical ingredients and powerful antioxidants specifically advanced glycation end-products. This unique treatment is formulated with an unprecedented 30% formulated to counter these advanced skincare concerns. concentration of Proxylane™ to help support skin's own GAG synthesis, and restore water and nutrients

to skin; blueberry extract to help prevent future wrinkles and laxity; and phytosphingosine to help protect BENEFITS the skin’s barrier to alleviate discomfort associated with dry, aging skin. • Helps correct visible signs of age-related skin damage • Supports replacement of lipids in dry skin BENEFITS • Soy isoflavones support natural collagen and hyaluronate production to firm skin • Improves skin creping and thinning • Soy, vitamin E, silymarin, and green tea extract help protect against free-radical damage • Corrects the appearance of fine lines, wrinkles, and rough texture • Formulated for dry, aging skin • Restores water and nutrients to improve skin elasticity • Restores comfort to dry, aging skin

A.G.E. EYE COMPLEX EYE BALM

A three-dimensional treatment designed exclusively for the delicate eye area, A.G.E. Eye A synergistic combination of highly effective, yet gentle, phytochemicals rehabilitates aging skin Complex significantly improves the appearance of dark circles, wrinkles, puffiness, and severe around the delicate eye area. This rich, corrective emollient treatment is specifically formulated signs of aging caused by internal factors such as glycation. This remedy for mature skin contains to counter three prime signs of aging: moisture loss, collagen breakdown, and free radical ProxylaneTM to reduce the appearance of wrinkles and crow’s feet while increasing skin elasticity damage. A marine extract relieves the appearance of under-eye puffiness, while a soothing agent and thickness; a complex of flavonoids and synergistic peptides to strengthen skin and diminish derived from the chamomile plant calms skin. the appearance of dark circles, puffiness, and under-eye bags; blueberry extract to help prevent

future wrinkles and crow’s feet; and optical diffusers to immediately boost the radiance of tired, BENEFITS dull eyes. • Helps correct age-related damage around the eye area • Improves the appearance of puffiness and wrinkles around the delicate eye area BENEFITS • Soy isoflavones support natural collagen and hyaluronate production to firm skin • Optical diffusers immediately boost radiance • Soy, vitamin E, and silymarin help protect against free-radical damage • Improves dark circles and puffiness • Formulated for dry, aging skin • Reduces the appearance of wrinkles and crow’s feet • Increases skin elasticity and thickness around the eyes • Restores comfort to dry, aging skin

32 33 SKIN FIRMING CREAM RETINOL 0.5

This powerful treatment is designed to correct early signs of environmental skin damage. Skin Retinol 0.5 contains 0.5% pure retinol and is enhanced with the latest stabilization and delivery Firming Cream contains ingredients that target environmental aggressors, repairing environmental technologies to provide maximum efficacy. Studies show retinol stimulates cellular turnover damage while firming the skin. This first line of defense supports skin’s natural ability to repair and supports skin’s own regeneration to diminish the appearance of fine lines, wrinkles, and damage caused by environmental elements. age spots from both environmental and intrinsic aging. Additionally, retinols help minimize the appearance of pore size, while reducing blemishes associated with problematic skin. Retinol 0.5

BENEFITS is ideal for continued use or for conditioning skin as a prerequisite to SkinCeuticals Retinol 1.0. • Centella asiatica helps firm and accelerate repair • Ectoin protects against stress factors and environmental aggressors BENEFITS • Supports skin's natural repair • Helps reduce the appearance of fine lines, age spots, blemishes, and blotchiness • Enhances hydration • Bisabolol calms skin and minimizes irritation commonly associated with the use of retinols • Suitable for normal, combination, and oily aging skin • Specialized packaging preserves optimal retinol stability • Delivery system ensures maximum amount of retinol reaches the target site • Will not clog pores • Ideal for most skin types

EYE CREAM RETINOL 1.0

Powerful ingredients work synergistically in this firming eye treatment to help correct early Ideal for problematic and photo-damaged skin, Retinol 1.0 contains 1% pure retinol, and should signs of aging. Eye Cream is formulated with a special complex to combat symptoms such as be used for advanced treatment of pre-conditioned skin. Designed for maximum efficacy and puffiness, sagging skin, and dark circles — all specific to the delicate eye area. This first line of stability, SkinCeuticals Retinol 1.0 is formulated with the highest concentration of pure retinol defense against environmentally-induced skin damage supports skin’s natural ability to repair available and enhanced with the latest stabilization and delivery technologies. Studies show retinol damage caused by environmental elements. stimulates cellular turnover and supports skin’s own regeneration to diminish the appearance of fine lines, wrinkles, and age spots from both environmental and intrinsic aging. Additionally,

BENEFITS it helps minimize the appearance of pore size, while reducing blemishes often associated with • Centella asiatica helps firm and accelerate repair problematic skin. • Ectoin protects against stress factors and environmental aggressors • Combats puffiness, sagging skin, and dark circles around the delicate eye area BENEFITS • Supports skin's natural repair • Helps reduce the appearance of fine lines, age spots, blemishes, and blotchiness • Enhances hydration • Bisabolol calms skin and minimizes erythema commonly associated with the use of retinols • Suitable for normal, combination and oily aging skin • Specialized packaging preserves optimal retinol stability • Delivery system ensures maximum amount of retinol reaches the target site • Will not clog pores • Ideal for most skin types exhibiting signs of photo-damage 34 35 ADVANCED PIGMENT CORRECTOR RETEXTURING ACTIVATOR®

Advanced Pigment Corrector is a daily multi-layer treatment to reduce stubborn discolorations and This revolutionary resurfacing and replenishing serum surpasses the results of a 20% daily gly- prevent reoccurrence. Featuring high-potency proven ingredients, ellagic acid and hydroxyphenoxy colic treatment while simultaneously reinforcing the skin’s barrier for healthier, more radiant propionic acid, this comprehensive approach exfoliates existing spots, inhibits unwanted widespread skin. Retexturing Activator harnesses two polar mechanisms — exfoliation and hydration — and localized pigmentation, and boosts skin's own resistance. Advanced Pigment Corrector is a to activate skin’s natural regenerative desquamation response, visibly diminishing surface lines and trans- highly effective and safe approach to address hyperpigmentation by boosting skin tone evenness forming skin’s fabric into a smoother, softer texture. Using patented technology, this unique treatment and radiance. It can also be used following cosmetic brightening procedures and prescriptions is highly effective at promoting cell turnover while optimizing the skin’s amino acid supply to to help maintain results. reinforce the barrier, resulting in the most efficient epidermal renewal. Potent without harsh side effects, Retexturing Activator is formulated in an efficient, oil-free delivery system. BENEFITS BENEFITS • Fades stubborn discolorations and enhances resistance to new pigment • Improves luminosity and skin tone evenness • Creates a noticeably smoother, softer surface texture • Clinically-tested on a multi-ethnic panel • Visibly diminishes surface lines and wrinkles • Paraben-free and fragrance-free • Dramatically improves skin’s radiance • Alternative to hydroquinone • Suitable for all skin types • Suitable for all skin types, except very sensitive

BLEMISH + AGE DEFENSE REDNESS NEUTRALIZER

Blemish + Age Defense is a targeted, oil-free serum uniquely designed to treat adult acne and signs Designed for sensitive and rosacea skin types, Redness Neutralizer is a lightweight gel cream that of aging. This first-to-market acid complex combines 2% dioic acid with LHA, salicylic, glycolic, strengthens the skin’s protective barrier, reduces redness and flushing by 30%, and alleviates signs and citric acids to reduce excess sebum production, prevent the formation of acne, minimize of irritation. Formulated with NeuroMed Complex, an innovative combination of biomimetic hyperpigmentation, and reduce the appearance of fine lines and wrinkles. neuropeptides and natural actives, Redness Neutralizer combats environmental triggers and the key steps of the inflammation cascade responsible for redness and flushing while reducing skin's BENEFITS temperature. Bisabolol, zinc gluconate, and shea butter further soothe and comfort skin. Also • Minimizes excess sebum production and reduces acne causing bacteria, P acnes suitable for treatment of age-related redness and blotchiness. • Improves inflammatory and non-inflammatory acne, while displaying exceptional tolerance • Helps prevent pigmentation caused by inflammation or UV exposure BENEFITS • Decongests clogged pores • Strengthens the skin’s protective barrier • Diminishes surface indicators of age • Slows the inflammation cascade that causes redness • Ideal for oily, combination, and aging skin types • Cools skin temperature • Paraben-free, fragrance-free, silicone-free, dye-free, alcohol-free and non-comedogenic • Formulated for all rosacea skin types

36 37 PHYTO + CLARIFYING CLAY MASQUE This botanical gel for discolorations and unwanted pigmentation combines four active ingredients to diminish discolorations and improve the overall health of the skin. Kojic acid and arbutin, This non-drying masque combines kaolin and bentonite, the highest-quality natural earth clays, natural alternatives to hydroquinone, work synergistically to help break up pigmentation to decongest pores and lift stubbornly-rooted impurities. Botanicals and minerals are added to clusters. Cucumber and thyme are known for their anti-inflammatory and purifying properties help calm the skin, while a 5% hydroxy acid blend gently exfoliates. Weekly use leaves skin to soothe red, irritated skin. Active ingredients are delivered in a hyaluronic acid base as it helps feeling healthy and purified. calm and improve the appearance of the skin. BENEFITS

BENEFITS • Natural earth clays, kaolin and bentonite, decongest pores, lift impurities, and help • Contains kojic acid and arbutin to help reduce and prevent discoloration remove excess oils • Contains anti-inflammatory cucumber and anti-bacterial thyme to soothe and calm irritated skin • 5% hydroxy acid blend gently exfoliates dead skin cells • Natural ingredient alternative to hydroquinone • Titanium dioxide, chamomile, and aloe soothes and calms skin • Ideal for all skin types • Ideal for all skin types

PHYTO CORRECTIVE GEL ANTIOXIDANT LIP REPAIR

Optimal for sensitive or problematic skin, this light, oil-free gel contains botanical extracts Designed specifically for damaged and aging lips, two powerful antioxidants, vitamin E and with anti-inflammatory and detoxifying properties to help soothe and calm irritated skin. silymarin, form a unique combination antioxidant emollient therapy to help protect against Phyto Corrective Gel contains natural alternatives to hydroquinone and other chemical environmental damage. This potent treatment smoothes and rehydrates the lip surface. A skin lighteners to help diminish the appearance of discolorations and promote a clear, complex of humectants and emollients rejuvenate and refine lip tissue, while replenishing fresh-looking complexion. Can be used to soothe redness after superficial chemical peels and actives restore moisture to hydrate and soften dry lips. Can be used daily, nightly, or as needed. similar rejuvenation treatments. BENEFITS BENEFITS • Helps protect against environmental damage • Contains anti-inflammatory cucumber and detoxifying thyme to soothe and calm irritated skin • Smoothes and rehydrates lip surface • Helps reduce post-treatment redness • Replenishes and refines lip tissue • Plant glycosides help minimize discolorations • Ideal complement for lip-drying side effects from prescription therapies • Excellent oil-free hydrator for blemish-prone skin • Paraben-free, fragrance-free, hygienic dispensing pump • Optimal for sensitive and problematic skin types • Suitable for all aging lip skin

38 39 EPIDERMAL REPAIR

Epidermal Repair is specifically formulated for skin compromised by cosmetic procedures ranging from microdermabrasion to laser resurfacing, as well as skin sensitized by retinoid therapy or harsh environmental aggressors. This therapeutic treatment combines beta glucan and centella asiatica to provide a protective veil for traumatized skin while facilitating the accelerated restoration of the skin’s barrier. Epidermal Repair greatly diminishes redness and soothes sensitized skin while the cosmetically elegant texture encourages daily use, especially during the critical healing period following rejuvenating procedures.

BENEFITS • Accelerates cell renewal and restoration of the skin’s barrier • Soothes skin and helps reduce signs of inflammation • Encourages barrier repair without occluding the skin • Ideal for post-procedure skin

BIOCELLULOSE RESTORATIVE MASQUE

Optimal for sensitive or compromised post-procedure skin, this highly efficient, supple, sterilized masque creates a protective barrier that helps facilitate the recovery process. The unique fibers distribute heat-absorbing water to the barrier, alleviating discomfort and providing immediate relief to heat-related side effects of clinical procedures. Clinically tested on compromised skin after laser procedures and chemical peels, this masque can also be used as a bi-weekly replenishing treatment.

BENEFITS • Acts as an artificial barrier to alleviate discomfort while allowing for breathability • Functions as a “heat absorber” to continuously cool and soothe • Replenishes and provides immediate relief to compromised skin • Suitable for all skin types

40 41 MOISTURIZE

SkinCeuticals are carefully formulated with multi-functional ingredients that nourish, protect, and exfoliate as they hydrate and restore elasticity. Our moisturizers are designed to maximize ingredient synergies and provide optimal benefits to the skin.

43 HYDRATING B5 GEL AGING ACNE HYPER- ROSACEA DEHYDRATED SENSITIZED DESCRIPTION Wrinkles | Laxity PIGMENTATION Enriched with vitamin B5 and hyaluronic acid, the body’s natural hydrator capable of absorbing Hydrating B Gel Replenishes moisture and restores 5 1,000 times its weight in water, Hydrating B5 Gel replenishes nutrients the skin needs to feel radiance for a smoother complexion N O D C S smooth and appear younger. Hydrating B5 Gel is recommended for use with vitamin C treatments Hyaluronic acid and vitamin B5 and will help maximize the benefits of a daily . Page 45

Hydrating B Masque Intensely hydrating weekly gel masque 5 BENEFITS to replenish moisture levels N O D C • Contains vitamin B to replenish nutrients Hyaluronic acid, vitamin B5, and advanced 5 Page 45 moisture complex • Binds moisture to the skin with hyaluronic acid, a natural humectant • Leaves skin feeling supple and smooth Emollience Restores and maintains moisture for dry or sensitive skin • Oil-free N D S Rich botanical extracts and nourishing • Ideal for all skin types Page 46 essential oils

Daily Moisture Provides normal or oily skin with lightweight hydration, while minimizing pores N O C Glycerin and purifying botanical extracts Page 46

Renew Overnight Dry Nighttime skin-refining moisturizer with fruit acid blend to hydrate and HYDRATING B5 MASQUE N D smooth skin Inspired by the award-winning Hydrating B5 Gel, this highly concentrated masque infuses Page 47 Fruit acid blend and rich botanical extracts dehydrated and stressed skin with high amounts of hyaluronic acid and vitamin B5 to replenish Renew Overnight Oily Nighttime skin-refining moisturizer depleted moisture levels. Enhanced with a unique complex containing constituents of the with fruit acid blend to hydrate and N O C skin’s natural moisturizing factor (NMF), skin’s system for maintaining hydration, this weekly decongest skin hydration treatment re-establishes the water balance critical for maintaining skin’s health. Page 47 Fruit acid blend and purifying botanical extracts Hydrating B5 Masque plumps moisture-deprived skin to restore a healthy, youthful appearance. Hydra Balm Hydrating occlusive ointment for traumatized or severely dry skin D S BENEFITS Pharmaceutical-grade petrolatum, emollient oils, • Contains a high concentration of hyaluronic acid to optimize moisture infusion in targeted areas Page 48 and aloe barbadensis • Contains two forms of vitamin B5 to help support skin's natural repair SKIN TYPES: N = Normal O = Oily D = Dry C = Combination S = Sensitive • Leaves skin feeling supple and smooth For optimal results, please consult with your physician. • Ideal complement to Hydrating B5 Gel for optimal hydration level maintenance • Suitable for all but sensitive skin types

45 EMOLLIENCE RENEW OVERNIGHT DRY

Formulated with an exclusive selection of rich botanical extracts and oils, this emollient This rich nighttime skin-refining moisturizer contains a fruit acid blend to gently exfoliate moisturizer is perfect for use on dry or sensitive skin. Three nutrient-rich sea algae nourish the skin for a healthier appearance. Formulated with extracts of aloe, chamomile, evening and hydrate the skin, while oils of grape seed, rose hip, and macadamia restore and maintain primrose oil, and comfrey, Renew Overnight Dry helps to restore a radiant complexion and moisture. Emollience is ideal for high altitudes and cold or dry climates. diminish the appearance of fine lines, wrinkles, and other signs of premature aging.

BENEFITS BENEFITS • Nourishes and hydrates the skin • 10% fruit acid blend works synergistically to gently exfoliate dead skin cells • Restores and maintains moisture • Nourishes and protects skin from dryness • Absorbs evenly and quickly • Helps restore a healthy radiant complexion • Ideal for high altitudes and cold or dry climates • Diminishes the appearance of fine lines, wrinkles, and other signs of premature aging • Optimal for dry and sensitive skin types • Formulated for normal and dry skin types

DAILY MOISTURE RENEW OVERNIGHT OILY

This lightweight pore-minimizing moisturizer hydrates, nourishes, and helps reduce the This purifying nighttime skin-refining moisturizer diminishes the appearance of fine lines and appearance of pore size with an exclusive combination of natural extracts. Glycerin draws water wrinkles by hydrating and exfoliating the skin. Special extracts help replenish moisture, while to the skin for non-greasy moisture, while sea algae deliver proteins, amino acids, and essential a fruit acid blend gently exfoliates to help restore a healthy, radiant complexion. Added orange minerals to the skin. Daily Moisture contains witch hazel, burnet, cinnamon, and ginger to help oil helps clear congested skin. tighten and reduce the appearance of pores.

BENEFITS BENEFITS • 10% fruit acid blend works synergistically to gently exfoliate dead skin cells • Nourishes and hydrates skin • Helps restore a healthy radiant complexion • Contains botanical extracts to help reduce visible pore size • Diminishes the appearance of fine lines, wrinkles, and other signs of premature aging • Restores and maintains moisture • Helps clear congested skin • Ideal for normal and oily skin types • Ideal for oily and combination skin types

46 47 HYDRA BALM

A multi-functional ointment ideal for treating symptoms associated with severely dry skin while improving overall hydration. This soothing balm forms a protective barrier on the skin while providing relief from itching and other irritations. Uniquely formulated to help lock in moisture, this balm maintains skin’s hydration levels longer than normal moisturizers. Proven safe to use post-laser (fractional ablative) treatments. Always consult with a physician for individual recommendations.

BENEFITS • Proven emollients deeply hydrate skin • Pharmaceutical-grade petrolatum provides an occlusive barrier over vulnerable skin • Squalene, rose hip oil, and aloe soothe skin, providing relief to dry and itchy skin • Ideal for extremely dry and sensitized skin types

48 49 PROTECT

SkinCeuticals sunscreens are formulated with combinations of highly effective physical or chemical sunscreens to provide true broad spectrum UVA/ UVB protection. By reflecting and absorbing UV rays, SkinCeuticals broad spectrum sunscreens are the skin’s first line of defense against photoaging. This advanced suncare line features Z-COTE®, transparent mineral zinc oxide, to physically protect skin from damaging UVA rays proven to be responsible for signs of premature aging.

SkinCeuticals offers a variety of cosmetically elegant sunscreen formulations for various skin types and lifestyles. This includes a full range of 100% mineral sunscreens ideal for daily use and very sensitive, post-procedure skin, as well as chemical sunscreens ideal for sport or extreme conditions.

® 50 Z-COTE is a registered trademark of BASF. 51 PHYSICAL FUSION UV DEFENSE SPF 50 AGING ACNE HYPER- ROSACEA DEHYDRATED SENSITIZED DESCRIPTION Wrinkles | Laxity PIGMENTATION Physical Fusion UV Defense SPF 50 provides broad spectrum UVA/UVB protection with all- Physical Fusion All mineral UVA/UVB fluid that provides physical filters, mineral zinc oxide (Z-COTE®), and titanium dioxide. Providing substantial UV Defense SPF 50 broad spectrum protection and enhances power in an ultra-sheer, mattifying fluid, this sunscreen is also infused with translucent color natural skin tone to boost radiance N D C S Translucent color spheres, zinc oxide (Z-COTE®), spheres to enhance natural skin tone. Tested on all ethnicities, this adaptable fluid provides Page 53 titanium dioxide, and artemia salina discreet coverage while restoring radiance. Paraben-free and safe for even very sensitive skin, this formula is boosted with artemia salina, a plankton extract which helps build skin’s natural Sheer Physical All mineral UVA/UVB fluid that provides defense and resistance to UV and heat stress. UV Defense SPF 50 broad spectrum protection with a transparent,

® N O C S weightless finish Zinc oxide (Z-COTE ), Page 53 titanium dioxide, and artemia salina BENEFITS

Physical Eye All mineral UVA/UVB eye base to enhance • Sheer, weightless texture that enhances natural skin tone and boosts radiance UV Defense SPF 50 skin tone • Discreet, diffusing coverage that adapts to all complexions

® N O D C S Zinc oxide (Z-COTE ), titanium dioxide, and • All-physical, broad spectrum UVA/UVB protection translucent color spheres Page 54 • Water-resistant (40 minutes), paraben-free, non-comedogenic Physical UV Defense All mineral UVA/UVB fluid that provides • ‘Shake then apply’ action evenly distributes active ingredients for enhanced effectiveness SPF 30 broad spectrum protection for sensitive, • Ideal for all skin types, even very sensitive very dry, and post-procedure skin N O D C S Zinc oxide (Z-COTE®), titanium dioxide, glycerin, Page 54 and artemia salina SHEER PHYSICAL UV DEFENSE SPF 50 Ultimate UV Defense Nourishing UVA/UVB cream SPF 30 Zinc oxide (Z-COTE®) and octinoxate Sheer Physical UV Defense provides an ultra-sheer, mattifying effect using all-physical broad N O D C spectrum filters. Through an optimized preservation system, minimized chemicals, and an Page 55 SPF 50 protection level, this paraben-free fluid with a transparent finish provides increased Sport UV Defense Broad spectrum, oxybenzone-free, protection in a well-tolerated formula. In addition to trusted broad spectrum, physical filters, SPF 50 UVA/UVB for active use transparent mineral zinc oxide (Z-COTE®) and titanium dioxide, this fluid is enhanced with N O D C Broad spectrum sunscreen and artemia salina artemia salina, a plankton extract that increases skin defenses and resistance to UV and heat Page 55 stress. This silky sheer fluid spreads evenly and dries quickly, leaving no residue. Daily Sun Defense Moisturizing UVA/UVB cream

® SPF 20 Zinc oxide (Z-COTE ) and octinoxate BENEFITS N O D C • Sheer, mattifying texture with a transparent finish Page 56 • All-physical, broad spectrum UVA/UVB protection SKIN TYPES: N = Normal O = Oily D = Dry C = Combination S = Sensitive • ‘Shake then apply’ action evenly distributes active ingredients for enhanced effectiveness For optimal results, please consult with your physician. • Paraben-free, non-comedogenic • Ideal for all skin types, even very sensitive

Z-COTE® is a registered trademark of BASF. Z-COTE® is a registered trademark of BASF. 53 NEW

PHYSICAL EYE UV DEFENSE SPF 50 ULTIMATE UV DEFENSE SPF 30

Physical Eye UV Defense SPF 50 is a daily non-migrating protective base to protect, even, and This broad spectrum sunscreen contains transparent mineral zinc oxide (Z-COTE®) and enhance the delicate skin around the eyes, including the eyelids. While skin around the eye is a chemical filter to help protect against the damaging effects of UVA and UVB rays. Cosmetically thinner and more susceptible to UV damage, this area goes largely unprotected and is a first area elegant and moisturizing, Ultimate UV Defense is ideal for daily use and perfect for high to exhibit signs of premature aging. Physical Eye UV Defense SPF 50 contains all-physical filters, altitudes, where climates can be drying to skin. featuring mineral zinc oxide (Z-COTE®) and titanium dioxide. A sheer coloration enhances radiance and uniformity around the eye, while the non-migrating base acts as a protective BENEFITS canvas for eye makeup. • Broad spectrum UVA/UVB protection with increased UVA protection • PABA-free and fragrance-free BENEFITS • Ideal for use in high altitudes • 100% mineral filters, broad spectrum UVA/UVB protection • Optimal for daily use on all skin types • Unifies skin tone around the eye • Enriched with ceramide to nourish the delicate eye area • Non-migrative base to avoid irritation to the eyes • Helps to offset discoloration post-injection • Creates a smooth canvas for optimal eye makeup application • Ophthalmologist-tested, contact lens compatible

PHYSICAL UV DEFENSE SPF 30 SPORT UV DEFENSE SPF 50

Formulated specifically for post-procedure, sensitive, and very dry skin, Physical UV Defense Tested under extreme athletic conditions, including full marathons, this broad spectrum, SPF 30 combines barrier repair and broad spectrum UVA/UVB protection. More advanced than lightweight, and 80 minute water-resistant sunscreen is proven not to interfere with vigorous traditional sunscreens, Physical UV Defense is proven to enhance the natural expression of workouts, resisting wear-off. This oxybenzone-free formulation is boosted with artemia salina, essential proteins responsible for skin’s barrier integrity. This all-physical sunscreen, featuring a plankton extract which helps build skin’s natural defense and resistance to UV damage and transparent mineral zinc oxide (Z-COTE®) and titanium dioxide, provides all-day hydration, heat stress. making it ideal for daily use. Artemia salina, a plankton extract, enhances this formulation by stimulating skin’s defenses and resistance to UV and heat stress. BENEFITS • Water-resistant (80 minutes) BENEFITS • Resists wear off from water, wiping, and rubbing • 100% mineral filters, broad spectrum UVA/UVB protection • Oxybenzone-free broad spectrum protection • Repairs and improves skin’s barrier function • Non-drying, alcohol-free, paraben-free, fragrance-free, and non-comedogenic • Supports skin’s natural production of key proteins responsible for skin barrier integrity • Suitable for most skin types • Provides all-day hydration in a nourishing, comforting texture • Paraben-free and fragrance-free • Ideal for post-procedure use, skin sensitive to traditional sunscreens, or for daily use

® ® 54 Z-COTE is a registered trademark of BASF. Z-COTE is a registered trademark of BASF. 55 DAILY SUN DEFENSE SPF 20

Optimal for daily use, this broad spectrum sunscreen contains transparent mineral zinc oxide (Z-COTE®) and a chemical filter to help protect against the damaging effects of UVA and UVB rays. This cosmetically elegant and moisturizing sunscreen is ideal for all skin types and can be applied under makeup. Daily Sun Defense does not contain PABA or fragrance.

BENEFITS • Broad spectrum UVA/UVB protection • Cosmetically elegant • PABA-free and fragrance-free • Recommended for daily use and suitable under makeup • Ideal for most skin types

® 56 Z-COTE is a registered trademark of BASF. 57 SKIN SYSTEMS

SkinCeuticals Skin Systems provide patients with high performance, clinical regimens designed to address special needs such as pre- and post-rejuvenation procedures, hyperpigmentation, acne, and environmental damage.

59 ADVANCED ANTI-AGING SYSTEM

This clinical regimen is proven to combat and prevent accumulated signs of damage by providing advanced daytime environmental protection and promoting skin’s nightly repair. This regimen counters the effects of glycation and accumulated damage to minimize the appearance of wrinkles, restore skin’s luminosity, and redensify skin.

INCLUDES

• C E FERULIC® AGING ACNE HYPER- ROSACEA DEHYDRATED SENSITIZED DESCRIPTION Delivers advanced environmental protection, while reducing fine lines and wrinkles Wrinkles | Laxity PIGMENTATION • A.G.E. INTERRUPTER Advanced Anti-Aging Clinical regimen to prevent and Diminishes the visible effects of glycation including creping, thinning skin System correct advanced signs of aging ® • RESVERATROL B E N D C S Includes C E Ferulic , Resveratrol B E, Page 61 and A.G.E. Interrupter Helps repair and prevent accumulated damage for improved radiance and elasticity

Adult Anti-Acne Clinical regimen to fight acne System and aging

O C Includes LHA Cleansing Gel, LHA Page 61 Solution, and Blemish + Age Defense

Advanced Brightening Clinical regimen to diminish dark ADULT ANTI-ACNE SYSTEM System spots and boost radiance ® This clinical regimen is proven to correct the signs of skin damage resulting from acne blemishes N O D C Includes Phloretin CF , Retexturing and aging, including enlarged pores, rough texture, and fine lines. The combination of these Page 62 Activator, Advanced Pigment Corrector, Retinol 0.5, and Physical Fusion UV products prevents the formation of acne, minimizes unwanted discolorations, and improves fine lines Defense SPF 50 and wrinkles. SKIN TYPES: N = Normal O = Oily D = Dry C = Combination S = Sensitive For optimal results, please consult with your physician. INCLUDES

• LHA CLEANSING GEL Exfoliating gel cleanser decongests pores, smoothes skin texture, and brightens skin • LHA SOLUTION Exfoliating toner removes excess residue and surface cells to decongest pores • BLEmISH + AgE DEfEnSE Prevents and reduces the formation of acne, minimizes blemishes, and reduces signs of aging

61 ADVANCED BRIGHTENING SYSTEM

This five-product regimen is clinically proven to significantly fade dark spots, dramatically brighten and even-out skin tone, minimize the appearance of fine lines and wrinkles, and help improve overall skin health.

INCLUDES

• PHLORETIN CF® Delivers advanced environmental protection, while diminishing discoloration • RETExTURIng ACTIVATOR Simultaneously exfoliates and replenishes moisture for smooth, radiant skin • ADVAnCED PIgmEnT CORRECTOR Reduces stubborn discolorations and prevents reoccurrence • RETINOL 0.5 Refines skin to diminish age spots, uneven tone, fine lines, and wrinkles • PHySICAL fUSIOn UV DEfEnSE SPf 50 Provides broad spectrum protection and enhances natural skin tone to boost radiance

62 63 NEW

BODY CORRECT

TRANSFORMATION ACTIVATING, PROCEDURE ENHANCING

Specifically created to complement leading in-office body procedures to smooth, tighten, rejuvenate, and brighten, SkinCeuticals Body Correct is a new generation of cutting-edge treatments targeted for high-demand body zones.

Efficient alone, these targeted topical technologies have been clinically tested to complement in-office body procedures, providing incremental benefits through different modalities at different time points for comprehensive results.

65 BODY TIGHTENING CONCENTRATE

Formulated for gravity-fighting body zones including the abdomen, buttocks, thighs, knees and upper arms, this cooling fluid reinflates and supports skin’s structure resulting in a smooth, taut surface. A combination of tripeptide, yeast extract, and hydrolyzed rice protein helps fill skin with volume while firming skin from within to tighten and lift loose, sagging areas. Proven safe and complementary to radiofrequency procedures.

BENEFITS

AGING ACNE HYPER- ROSACEA DEHYDRATED SENSITIZED • Tightens and lifts loose, sagging skin PIGMENTATION DESCRIPTION Laxity | Roughness • Firms and smoothes skin Body Tightening Tightens, firms, and lifts loose, sagging skin • Improves appearance and resilience of gravity-fighting zones Concentrate Tripeptide, yeast extract, hydrolyzed rice protein • Tested safe for use with radiofrequency tightening procedures N O D C S

Page 67

Body Retexturing Exfoliates and hydrates simultaneously Treatment to resurface dull, rough skin Hydroxyethyl urea/aminosulfonic acid, N O D C S niacinamide, hyaluronic acid Page 67 BODY RETEXTURING TREATMENT

Neck, Chest & Brightens age spots and redensifies skin Formulated for dull, rough body skin, especially arms, legs, knees, and elbows, Body Retexturing Hand Repair to minimize crepiness Treatment harnesses two polar mechanisms – exfoliation and hydration – to transform skin Hydroxyphenoxy propionic acid, sodium N O D C S into a smoother, softer texture. Hydroxyethyl urea/aminosulfonic acid compound normalizes tetrahydrojasmonate, vigna aconitifolia cell turnover and restores skin’s barrier, resulting in the most efficient epidermal renewal. Page 68 seed extract Hyaluronic acid increases skin’s natural moisturizing factor (NMF) for additional hydration,

SKIN TYPES: N = Normal O = Oily D = Dry C = Combination S = Sensitive while niacinamide enhances skin’s anti-inflammatory response. This powerful resurfacing and

For optimal results, please consult with your physician. replenishing gel formulation is ideal for all skin types, including extremely dry, flaking skin. Safe to use after laser treatments, and can be used between these treatments to encourage follicular exfoliation.

BENEFITS • Resurfaces rough body zones • Provides simultaneous hydration and exfoliation • Significantly improves radiance and softness • Tested safe for use with procedures

67 NECK, CHEST & HAND REPAIR

Specifically designed for neglected body areas frequently exposed to the sun, Neck, Chest & Hand Repair delivers dual brightening and restoration action. Hydroxyphenoxy propionic acid helps remove surface pigmentation and inhibits unwanted pigmentation, while sodium tetrahydrojasmonate and vigna aconitifolia seed extract promote cellular renewal and support skin's structure to alleviate crepiness. Proven safe after laser treatments and can be used to help maintain laser results long-term.

BENEFITS • Brightens and evens skin tone on areas with accumulated damage • Fades age spots • Redensifies skin to minimize crepiness • Tested safe for use with laser rejuvenation procedures

68