ANTIOXIDANT AUTHORITY High Potency Formulas to Improve Skin Health and Combat Aging 1.OUR FOUNDATIONS

ANTIOXIDANT AUTHORITY High potency formulas to improve skin health and combat aging 1.OUR FOUNDATIONS

4 GENERATIONS OF ANTIOXIDANT BREAKTHROUGHS 10 ANTIOXIDANT PATENTS AND 20+ PEER-REVIEWED STUDIES ANTIOXIDANT PIONEER Created in 1997 thanks to the work of Dr Sheldon Pinnell – a renowned American dermatologist, who was the first to stabilise pure Vitamin C at a high concentration and a low pH into a cosmetic solution – SkinCeuticals provides advanced anti-aging skincare breakthroughs at the forefront of antioxidant technology and helped pioneer the advent of cosmeceuticals* in the USA.

ANTI-AGING EXPERT SkinCeuticals’ mission is to improve skin health. Dedicated to this purpose, we make one simple promise - provide advanced skincare backed by science.Born from decades of skin cancer research, our high potency formulas are concentrated in pure actives and proven to penetrate optimally into skin. Made in the USA, we are used and recommended by dermatologists and plastic surgeons, select pharmacies and premium spas to both correct the signs of aging and prevent future damage.

THE MEDISPA REFERENCE SkinCeuticals is used in cabin treatments together with professional skincare protocols and clinical procedures. The brand is recommended by the best dermatologists and plastic surgeons and SkinCeuticals is now distributed by close to 4,000 dispensing clinics and medispas around the world.

*Cosmeceuticals are products that are at the frontier between cosmetics and drugs. 2. OUR PHILOSOPHY A 3-STEP ANTI-AGING ROUTINE

There are three fundamental steps to prevent and to correct signs of aging caused by environmental assaults and UV exposure.

ANTIOXIDANT SERUMS Neutralize free radicals generated as a reaction to environmental attacks (UV rays, pollution, stress, smoke). 1 Act to reinforce the skin’s natural antioxidant defences against free

PREVENT radicals.

SUNSCREENS (Broad-spectrum filters) Form a barrier against damaging UVA/UVB rays, responsible for the acceleration of natural aging. 2 Act on the surface of the skin, to protect skin from free radical

PROTECT attacks, in order to complement the action of antioxidants.

SPECIFIC CORRECTIVE TREATMENTS Repair the skin thanks to powerful formulas enriched with reparative, brightening and exfoliating active ingredients, derived from 3 dermatological practices and formulated in optimal concentrations, proven to penetrate optimally into skin. CORRECT 3. OUR MODEL INTEGRATED SKINCARE At SkinCeuticals we believe the best way to improve skin health is to protect skin, prevent future damage, and correct existing aging through cosmetic procedures, professional treatments, and home care products that support the skincare goals of physicians and patients.

PROFESSIONAL USE HOME CARE

2 ways of using SkinCeuticals products 3 ways of using SkinCeuticals products by professionals: as home care: PROFESSIONAL SKINCARE PROTOCOLS/FACIALS PRE-CONDITION Preparation for cosmetic procedures Protocols with SkinCeuticals products only POST-PROCEDURE To enhance results and/or soothe skin CLINICAL PROCEDURES DAILY-USE Procedures in combination with SkinCeuticals products Example: laser, peel, botox, filler, medical needling HOME CARE PRE-CONDITION

PROFESSIONAL COSMETIC SKINCARE PROCEDURES PROTOCOLS

HOME CARE HOME CARE DAILY-USE POST-PROCEDURE PREVENT PHLORETIN CF & C E FERULIC REVERSE EXISTING DAMAGE, STOP THE AGING RELAPSE

AN ANTIOXIDANT A DAY KEEPS SKIN AGING AWAY Excessive exposure to ultraviolet light as well as the natural aging process depletes the body of its internal supply of antioxidants. SkinCeuticals’ topical antioxidants prevent oxidative damage.

SkinCeuticals’ 30 years of academic research have demonstrated that, for a topical antioxidant to be efficient: Penetration needs to be proven Specific antioxidant combinations provide superior results to single AOX formulations Biological effects in skin have to be demonstrated – by analysing key biomarkers

C E Ferulic and Phloretin CF increase the body’s antioxidant natural reservoir to provide unmatched protection from the sun. The additional benefit: improved radiance and texture, reduced lines and wrinkles. Each combination has its own specificities.

PHLORETIN CF C E FERULIC 2% Phloretin, 10% L-Ascorbic Acid, 0,5% Ferulic Acid 15% L-Ascorbic Acid, 1% a-Tocopherol, 0,5% Ferulic Acid Boosts skin’s structure Protects the lipidic film Diminishes age and brown spots Stimulates collagen synthesis to improve firmness and elasticity Ideal for combination to normal skin Ideal for normal to dry skin Controlled delivery for enhanced tolerance

P53, an essential protective tumor protection suppression protein in skin, C E Ferulic yields 8x the skin’s natural protection from the sun. is increased when skin is damaged. In vivo, skin protected with Phloretin CF shows significantly lower levels of P53 compared to placebo. PROTECT ULTRA FACIAL DEFENSE SPF 50 & SHEER MINERAL UV DEFENSE SPF 50 BROAD SPECTRUM PROTECTION

DAILY UVA/UVB EXPOSURE ACCELERATES SKIN AGING UVB rays are responsible for sunburn UVA rays represent 95% of the UV that reaches our skin all year round and generate free radicals Oxidation of skin’s pigment: skin darkening and more visible brown spots Damage to fibroblasts (cells that produce collagen and elastin) inducing wrinkles and loss of firmness

ULTRA FACIAL DEFENSE SPF 50 SHEER MINERAL UV DEFENSE SPF 50

Mexoryl® SX/XL, Tinosorb® S,Titanium Dioxide 100% mineral filters Designed for all skin types, even very sensitive, Designed for all skin types, hypoallergenic and oily or acne-prone skin non-comedogenic formula Ultra-fluid, matifying texture Ultra-light texture with long-lasting hydration (12 hours) Transparent finish, water and sweat resistant Good make-up base: no whitish effect Paraben-free, chemical-filter free: ideal for compromised Fragrance free skin after cosmetic procedures SkinCeuticals also provides a complete corrective product line that combines powerful formulas enriched with reparative, brightening and exfoliating ingredients to help improve your patients’ skin. CORRECT BLEMISH & AGE DEFENSE SO EFFICIENT ON IMPERFECTIONS, IT GOES BEYOND TO TREAT SIGNS OF AGING

THE INTERSECTION BETWEEN BLEMISHES AND AGING After years of effective but dehydrating and sensitizing drug therapies, many adults suffering from blemishes are ready to transition to a more tolerable yet efficient solution to treat breakouts while improving overall complexion.

2% ANTI-IMPERFECTIONS DIOIC ANTI-AGING ACID 1,5% Salicylic Acid 3,5% Glycolic Acid 0,3% LHA 0,5% Citric Acid

AS EFFECTIVE AS TRETINOIN* WITH SIGNIFICANTLY BETTER RESULTS IN 3 KEY ATTRIBUTES: Blemish + Age Defense is shown to be statistically better than Tretinoin in improving skin tone (weeks 1,4 and 8) and blotchiness (weeks 4 and 8) and in reducing total lesions (weeks 1 and 8).

*Study carried out on 18-40 year old males and females with mild to moderate acne (at least 4 inflammatory lesions and seven non-inflammatory lesions, no cysts), mild to moderate fine lines and wrinkles, 8 weeks of treatment. INTERNATIONAL PRODUCT LINE RETAIL A COMPLETE AND HIGH POTENCY ANTI-AGING SKINCARE LINE

C E FERULIC PHLORETIN CF PHLORETIN CF GEL AOX+ EYE GEL PREVENT

High potency antioxidant formulas designed to prevent skin damage from the inside

BRIGHTENING UV ULTRA FACIAL SHEER MINERAL UV DEFENSE SPF 30 DEFENSE SPF 50 DEFENSE SPF 50 PROTECT

Broad-spectrum protection from damaging UVA and UVB rays

FACE FACE EYE RETINOL RETEXTURING A.G.E A.G.E EYE PHYTO PIGMENT CLARIFYING BLEMISH & AGE CORRECT CREAM BALM BALM 0.3 ACTIVATOR INTERRUPTER COMPLEX CORRECTIVE REGULATOR CLAY DEFENSE MASQUE Formulas enriched with reparative, exfoliating and brightening ingredients for advanced correction

DAILY MOISTURE EMOLLIENCE HYDRATING B5 HYDRATING B5 MASQUE MOISTURIZE

Formulas enriched with multifunctional ingredients to hydrate and nourish

GENTLE CLEANSER SIMPLY CLEAN EQUALIZING BLEMISH & AGE BLEMISH & AGE TONER CLEANSING GEL SOLUTION CLEANSE & TONE

Formulas containing a variety of active ingredients to lift impurities and gently exfoliate dead skin cells INTERNATIONAL PRODUCT LINE PRO A COMPLETE AND HIGH POTENCY ANTI-AGING SKINCARE LINE SkinCeuticals provides professional-size products and protocols that have been developed to achieve the highest standards in cosmetic treatments.

C E FERULIC PHLORETIN CF PREVENT

High potency antioxidant formulas designed to prevent skin damage from the inside

BRIGHTENING UV DEFENSE SPF 30 PROTECT

Broad-spectrum protection from damaging UVA and UVB rays

FACE FACE EYE RETEXTURING A.G.E PHYTO CLARIFYING BLEMISH & VITAMIN C PIGMENT BALANCING PEEL CORRECT CREAM BALM BALM ACTIVATOR INTERRUPTER CORRECTIVE CLAY AGE FIRMING PEEL NEUTRALIZER MASQUE DEFENSE MASQUE (Booster, Solution, Powder) Formulas enriched with reparative, exfoliating and brightening ingredients for advanced correction

DAILY MOISTURE EMOLLIENCE HYDRATING B5 HYDRATING B5 MASQUE MOISTURIZE

Formulas enriched with multifunctional ingredients to hydrate and nourish

GENTLE CLEANSER SIMPLY CLEAN EQUALIZING TONER BLEMISH & AGE BLEMISH & AGE MICRO GEL SOUTION POLISH CLEANSE & TONE

Formulas containing a variety of active ingredients to lift impurities and gently exfoliate dead skin cells A PROFESSIONAL MEDICAL NETWORK EXPANDING WORLDWIDE SkinCeuticals is present in the following countries: Austria, Brazil, Canada, China, Colombia (2012),United Arab Emirates, France, Germany, Hong Kong, Italy, Japan, Korea, Lebanon, Mexico (2012), Poland, Portugal, Russia, Singapore, Saudi Arabia, South Africa