TRANSFER the Steinbeis Magazine

TRANSFER The Steinbeis Magazine Life Through a Magnifying Glass Feature Topic: Life Science Experts at Steinbeis play a pivotal role in a variety of projects Cross-border Enthusiasm for Science Steinbeis Romania acts as project partner to European initiative Well Welded, Whatever the Position Steinbeis experts develop orbital micro-plasma powder welding torch Creating a Map for Corrosion Steinbeis experts map global corrosion conditions for metal components 02 | 2018 2 CONTENT Editorial 03 “The diversity of people is an enrichment” 04 A TRANSFER interview with PRISMA CEO Stefan Nachbaur Feature Topic: Life Science 05 Insights from Steinbeis experts into recent projects Can Nanoparticles Make People Sick? 06 A team of Steinbeis experts draws on the findings of stem cell research into environmental toxicology “At the end of the day, the key consideration has to be what is best for the patient“ 08 An interview with Professor Dr. Tobias Preckel, director of the Steinbeis Transfer Center Medical Engineering & Life Sciences, and Professor Dr. Sascha Seifert, director of the Steinbeis Transfer Center E-Health-Systems and Medical Informatics WeSeniMuS: Wearable Technology in MS Research 10 The use of mobile technology and wearables in clinical studies “It’s not just the medical experts who have challenges to face, but the entire healthcare system” 12 Innovation in the Craft Industry – Locally and Internationally 34 An interview with Professor Dr. Hans-Peter Deigner, director of the S2i provides advice on going international and innovation Steinbeis Transfer Center for Personalized Medicine management Minimizing Risk with IMMODGEL and PANBioRA 14 Creating a Map of Corrosion 36 New research findings on the prevention of immune responses after Steinbeis experts map global corrosion conditions for the fitting of implants and assessing the risk posed by biomaterials metal components „Combining ultrastructural and molecular biology analysis Social Entrepreneurship – A Corporate Mission to would be ideal for gaining new insights“ 16 Solve Social Issues 38 An interview with Professor Dr. Ulrich Schraermeyer, director of the Steinbeis University alumnus sets up web-based platform for Steinbeis Transfer Center OcuTox acquiring competencies Innovation Knows No Borders 18 Welcome to the Steinbeis Network 39 Steinbeis Innovation Center coordinates cross-sector business network Current 40 for medical technology New releases from Steinbeis-Edition 42 „A technology isn’t an end in itself – it’s an engine of innovation“ 20 An interview with Professor Dr. Ralf Kindervater, director of BIOPRO Baden-Württemberg GmbH An Impressive Treatment: Enzyme Therapy 22 Steinbeis experts conduct research into diagnostic and treatment processes for lysosomal storage diseases Leveraging the Full Potential of Digital Solutions 24 EU-backed training on digital solutions in the healthcare industry Spotlight 26 Cross-border Enthusiasm for Science 28 Steinbeis Romania acts as project partner to European initiative Everyone on Board? 30 Steinbeis experts use digital onboarding to introduce new employees to a company Find an overview of all Steinbeis Enterprises Well Welded, Whatever the Position 32 and their services on www.steinbeis.de → network Steinbeis experts develop orbital micro-plasma powder welding torch Technology.Transfer.Application. TRANSFER 02|2018 EDITORIAL 3 Dear Readers, The feature topic of this issue of TRANSFER is life science and its important influence as a key area of inter- disciplinary research and development. The German economy would be inconceivable without the work going on in the fields of health care, food and beverage development, food safety, environmental chemistry, and environmental medicine. So this topic represents an important area of transdisciplinary collaboration between companies, academic institutions, and research centers in the Steinbeis Network, also reflecting key areas of interest within the Steinbeis organization: innovation, the sharing of competence, and know-how transfer. The articles in this magazine provide some good examples of the know-how offered by Steinbeis Enterprises. They look at environmental toxicology using stem cell research, there is an outline of the latest results derived from patho-immunology in transplantation medicine (certainly an area of research that was neglected in the past), and we provide insights into the development and application of new technologies and digital methods in clinical medicine. In terms of new pharmaceutical developments, especially new techniques used in immune therapy, the characterization of antibodies is of central importance. The analysis of antibody epitopes de- Professor Dr. Dr. h. c. Michael scribed in this issue (the molecular recognition structures of antibodies) revolves around mass spectrometry, Przybylski is director of the and this not only offers an essential starting point for new therapeutic antibodies (for example, in cancer Rüsselsheim-based Steinbeis therapy). These processes are gaining in importance when it comes to the characterization of pathophysiolo- Transfer Center for Biopolymer gical antibodies during treatment, especially when it involves genetic engineering and synthetic proteins. One Analysis and Biomedical Mass major problem, which often acts as a limitation in the treatment of lysosymal spinal disease based on enzyme Spectrometry. The work carried replacement therapy, is the formation of antibodies. By identifying antibody epitopes, it becomes possible to out at the center includes the develop new methods for molecular diagnostics and treatment. structure identification of mem- brane proteins, the synthesis and I hope this issue of TRANSFER stimulates plenty of exchange and discussion, that it encourages closer colla- structural analysis of modified boration on new technology – even supposedly unconnected technologies – and that this brings us nearer to proteins, and the identification the future goal of developing personalized medicine and health research. of structures in autoimmune diseases. With kind regards, In 2010, Przybylski, his center, Michael Przybylski and its industrial partner Genzy- me CEE won the Steinbeis Foun- dation Transfer Award – the Löhn Award. The project partners jointly developed methods used in the clinical diagnosis of lysosomal storage diseases in Central and Eastern Europe. To contact Michael Przybylski, write to [email protected]. Steinbeisverbund SteinbeisGlobal Channel: Steinbeis Steinbeis Technology.Transfer.Application. TRANSFER 02|2018 4 a building called kup. Ravensburg. It’s a working environment of- fering an integrated co-working space brimming with ideas and energy. At the same time, the building has integrated support facilities for people with disabilities. What was your motivation for working on this highly diverse and inclusive project? The worlds of work and everyday life are changing continuously, as is society’s approach to living together. This is a process that’s enriching, not only for the innovative power of companies, but also for the diversity of all people, with or without disabilities. kup. Ravensburg is the answer to a ques- tion: How do we want to live and work together in the future? But at the same time, this is the motivation for everything we do. It’s what drives us. PRISMA works with a number of partners as part of an initiative called Start (k)up, focusing on the main thrusts of your projects. So you develop reliable partnerships that allow value to be added “The diversity of people is on a number of fronts. Just some of the things this involves are shared projects, providing support to established companies and an enrichment” business founders, and networking events. What other plans does the initiative have? A TRANSFER interview with PRISMA CEO Stefan Nachbaur Completing kup. Ravensburg essentially provided the Start (k)up. initiative with a physical springboard, so it makes it possible to actually go Stefan Nachbaur is passionate about networking. As CEO of the about implementing things and making things happen. We’re taking PRISMA group of companies in Vorarlberg and Germany, he plays topics like innovation management, intercultural issues, and startups to an active cross-border role in economic and regional development. kick-start a series of networking events and a whole variety of consul- It would be mistaken to think that this is just about overseeing real ting services. The collaboration partners are playing an active role in estate development. In addition to developing urban districts, city this area and are part of the process. centers, innovation hubs, technology centers, business zones, and industrial areas, his work also involves establishing networked col- laboratives to come up with new ideas, sponsoring institutions that Start (k)up. Ravensburg operate care homes and supervised accommodation, and working with business startup models. When you meet the energetic net- Steinbeis is a member of a network called Start (k)up. Ravensburg, worker, it immediately strikes you that for him, the success of a which provides support to business founders, spinoffs, and estab- development project is inseparably connected with a constructive lished companies in the economic zones of Lake Constance, Upper exchange of ideas and collaboration between companies, communi- Swabia, Allgäu, and Vorarlberg. The network’s aim is to establish a ties, and regional initiatives and associations. TRANSFER met up startup-friendly environment in the local economy by providing

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