US 20130209.617A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2013/0209617 A1 Lobisser et al. (43) Pub. Date: Aug. 15, 2013 (54) COMPOSITIONS AND METHODS FOR USE Publication Classification IN PROMOTING PRODUCE HEALTH (51) Int. Cl. (75) Inventors: George Lobisser, Bainbridge Island, A23B 7/16 (2006.01) WA (US); Jason Alexander, Yakima, (52) U.S. Cl. WA (US); Matt Weaver, Selah, WA CPC ........................................ A23B 7/16 (2013.01) (US) USPC ........... 426/102: 426/654; 426/573; 426/601; 426/321 (73) Assignee: PACE INTERNATIONAL, LLC, Seattle, WA (US) (57) ABSTRACT (21) Appl. No.: 13/571,513 Provided herein are compositions comprising one or more of (22) Filed: Aug. 10, 2012 a stilbenoid, stilbenoid derivative, stilbene, or stilbene deriva tive and a produce coating. The resulting compositions are Related U.S. Application Data coatings which promote the health of fruit, vegetables, and/or (60) Provisional application No. 61/522,061, filed on Aug. other plant parts, and/or mitigate decay of post-harvest fruit, 10, 2011. Vegetables, and/or other plant parts. Patent Application Publication Aug. 15, 2013 Sheet 1 of 10 US 2013/0209.617 A1 | s N i has() 3 S s c e (9) SSouffley Patent Application Publication Aug. 15, 2013 Sheet 2 of 10 US 2013/0209.617 A1 so in a N s H N S N N. sr N re C c g o c (saulu) dae. Patent Application Publication Aug. 15, 2013 Sheet 3 of 10 US 2013/0209.617 A1 N Y & | N Y m N 8 Š 8 S. s 3 8 8 S. & Patent Application Publication Aug. 15, 2013 Sheet 4 of 10 US 2013/0209.617 A1 N I NN 3 8 r (Sc) E-Aufisyu alo Patent Application Publication Aug. 15, 2013 Sheet 5 of 10 US 2013/0209.617 A1 : | N S S s Patent Application Publication Aug. 15, 2013 Sheet 6 of 10 US 2013/0209.617 A1 | N H Patent Application Publication Aug. 15, 2013 Sheet 7 of 10 US 2013/0209.617 A1 : i | N | N Patent Application Publication Aug. 15, 2013 Sheet 8 of 10 US 2013/0209.617 A1 Patent Application Publication Aug. 15, 2013 Sheet 9 of 10 US 2013/0209.617 A1 I N N (SCI) Hyo Patent Application Publication Aug. 15, 2013 Sheet 10 of 10 US 2013/0209.617 A1 (SCI) HNO US 2013/0209.617 A1 Aug. 15, 2013 COMPOSITIONS AND METHODS FOR USE 0017 FIG. 5 shows Average firmness in region 1 (A1) IN PROMOTING PRODUCE HEALTH values in lbs for Gala apples. 0018 FIG. 6 shows Average Firmness in region 2 (A2) RELATED APPLICATIONS values in lbs for Gala apples. “Initial indicates value at day 0001. This application claims priority under 35 U.S.C. Zero before coatings were applied. 119 (e) to U.S. Provisional Patent Application Ser. No. (0019 FIG. 7 shows Maximum firmness in region 1 (M1) 61/522,061, entitled “COMPOSITIONS AND METHODS values in lbs for Gala apples. FOR USE IN PROMOTING PRODUCE HEALTH', filed 0020 FIG. 8 shows Maximum firmness in region 2 (M2) Aug. 10, 2011, the disclosure of which is hereby incorporated values in lbs for Gala apples. “Initial indicates value at day by reference in its entirety. Zero before coatings were applied. (0021 FIG.9 shows Overall average hardness (OAH) val FIELD ues in lbs for Gala apples. 0002 This disclosure relates to produce coatings, and in (0022 FIG. 10 shows Overall maximum hardness (OMH) particular, produce coatings which promote the health of values in lbs for Gala apples. fruit, vegetables, and/or other plant parts, and/or mitigate decay of post-harvest fruit, vegetables, and/or other plant SUMMARY parts. 0023 Provided herein are compositions useful in the food industry as coatings for fruits, vegetables, and other plants BACKGROUND and plant parts. In some embodiments, the compositions 0003. The statements in this section merely provide back comprise a produce coating, e.g. a coating containing shellac ground information related to the present disclosure and may or a carnauba wax, and one or more stilbenoid compounds. In not constitute prior art. Some aspects, the stilbenoid compound is a stilbene deriva 0004 Most fruit and vegetable products are harvested in a tive, a stilbene oligomer, stilbene, a stilbenoid derivative, or a fairly narrow time period or season. However, consumer stilbenoid oligomer. demand remains high for fresh produce out of season. Often, 0024. Also provided herein are food products comprising fresh produce is transported hundreds of miles from the initial a fruit, vegetable, or other edible plant part having a compo site of harvest and stored for many months after harvest. For sition applied to the Surface. Useful compositions are dis these reasons, it is desirable to extend produce shelf-life. closed herein, for example, compositions comprising: i) a 0005. The typical shelf-life of a fruit or vegetable (fresh wax, oil, resin, protein, carbohydrate, phospholipid, gum, produce) depends on several factors including ripeness at silicone, or polydimethysiloxane; and ii) one or more com time of harvest, handling conditions, and storage conditions. pounds selected from the group consisting of resveratrol, 0006. A common method for extending the post-harvest stilbene, pterostilbene, piceid, e-Viniferin, piceatannol, dip storage of fruit and vegetables is the use of edible coatings. toindonesin A, pinosylvin, astringin, Vaticanol B, trans-dip Most fruits are susceptible to post-harvest deterioration toindonesin B, hopeaphenol, hemsleyanol D. gnetin H, brought about by water loss, gas exchange, bruising, ampelopsin A, ampelopsin E, and alpha-Viniferein. mechanical injury, and microbial growth. 0025. Further provided are methods of maintaining health 0007 U.S. Pat. No. 3,847,641 to Cushman et al. purport of a fruit, vegetable, or other edible plant part. The methods edly mentions wax emulsion compositions for controlling comprise contacting the Surface of the fruit, vegetable, or transpiration in plants. other edible plant part with a composition comprising a pro 0008 U.S. Pat. No. 5,019,403 to Krochta purportedly duce coating and one or more stilbenoid compounds. Exem mentions coating compositions for Substrates such as edible plary compositions are described herein, for example, pro agricultural products. duce coating compositions comprising one or more stilbenoid 0009 U.S. Pat. No. 6,482,455 to Freire et al. purportedly compounds such as a stilbene derivative, a stilbene oligomer, mentions compositions for the control of post-harvest stilbene, a stilbenoid derivative, or a stilbenoid oligomer. pathologies of fruits and vegetables. 0026. Still further methods provided herein include meth 0010 Further effort is needed to find coatings which ods of mitigating decay of post-harvest produce and methods improve produce health or mitigate decay of post-harvest of maintaining firmness of post-harvest produce. Composi fruits, vegetables, and other plant parts, leading to a longer tions described hereinareuseful in these and other methods as storage life while maintaining quality sensory traits. will be understood by one skilled in the art. 0011. The present invention is directed toward overcom 0027. Further areas of applicability of the present teach ing one or more of the problems discussed above. ings will become apparent from the description provided herein. It should be understood that the description and spe BRIEF DESCRIPTION OF THE DRAWINGS cific examples are intended for purposes of illustration only and are not intended to limit the scope of the present teach 0012. The drawings described herein are for illustration 1ngS. purposes only and are not intended to limit the scope of the present disclosure in any way. DETAILED DESCRIPTION 0013 FIG. 1 shows Percent weight loss for Gala apples. UTC is the untreated control (no coating applied). 0028. The following description is merely exemplary in 0014 FIG. 2 shows Creep (CO) values in inches for Gala nature and is not intended to limit the present disclosure, apples. application, claims, compositions, or uses. 0015 FIG.3 shows Crispness (Cn) values for Gala apples. 0029 Disclosed herein are compositions comprising phy 0016 FIG. 4 shows Core integrity (E2) values in lbs for toalexins and methods of using those compositions to pro Gala apples. mote fruit health and/or mitigate decay of post-harvest fruit. US 2013/0209.617 A1 Aug. 15, 2013 In some embodiments, the compositions comprise stilbenes, 0033 Stilbenoid-2-carboxylic acid derivatives have been stilbene derivatives, and/or stilbene oligomers. In some isolated from various plants. Hydrangeic acid (3,4'-dihydrox embodiments, the compositions comprise stilbenoids, stil yStilbene-2-carboxylic acid) was reported isolated from the benoid derivatives, and/or stilbenoid oligomers. In some common garden hydrangea (Hydrangeqa macrophylla) embodiments, the compositions comprise resveratrol, res Pryce, R. J., Phytochemistry 10, 2679 (1971). A glycoside, Veratrol derivatives, and resveratrol oligomers. gaylussacin, reported isolated from Gaylussacia frondosa, 0030 Stilbenoids, including for example, stilbene, res and G. vassata (Ericaceae), produced a 3.5-dihydroxyStill Veratrol, pterostilbene, piceid, e-Viniferin, piceatannol, and bene-2-carboxylic acid derivative (gaylussacin aglycone). diptoindonesin A, are isomeric hydrocarbon compounds con Askari, A., et al., Lloydia 35.49 (1972). taining an ethene double bond substituted with an unsubsti 0034) Four isoprenylated stilbene 2-carboxylic acid phy tuted or substituted phenyl group on both carbonatoms of the toalexins (3-hydroxy-5-methoxy-6-(3-methyl-2-butenyl) double bond. The term stilbenoid refers to stilbenes, biben stilbene-2-carboxylic acid, 3-hydroxy-5-methoxy-4-(3-me Zyls (7,8-dihydrostilbenes), and phenyldihydroisocoumarins thyl-2-butenyl)stilbene-2-carboxylic acid, 3,5-dimethoxy-6- together with a number of nitrogen free phenatlirenols, which (3- methyl-2-butenyl)stilbene-2-carboxylic acid, and 3.5- are thought to be products of the same metabolic pathway that dimethoxy-4-(3-methyl-2-butenyl)stilbene-2-carboxylic leads to stilbenes.