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25.3 Joana Final Draft Mike Format 19 January 2016 ISAR News Vol. 25 No. 3 Editor Anthony Vere Hodge Guest editor, Joana Rocha-Pereira ©International Society for Antiviral Research La Jolla, CA, USA welcomes the 29th ICAR, 17-21 April 2016 at IN THIS ISSUE ISAR PRESIDENT’S MESSAGE ISAR President’s Message I would like to offer a warm welcome to all of our ICAR 2016 members to the 29th International Conference on Update on the 29th ICAR Antiviral Research which will be held in La Jolla, CA Invitation to La Jolla in April 2016. Our meeting this year will commence Women in Science on the afternoon of Sunday April 17th with Drug th Discovery 101 and conclude midday on Thursday 29 ICAR: Useful information April 21st. In between, Mark Prichard and the ISAR elections - Our new officers Program Committee have put together a top notch Current research scientific program which includes two Keynote New infection models for human norovirus Addresses, two mini-symposia, our annual Prusoff, drug development Elion and Holy award lectures, and a variety of Antivirals on the horizon podium presentations and posters based on submissions from our delegates. Mark has worked MERS-coronavirus: a moving target? diligently this year to also incorporate a novel session ICAR through the years on diagnostic technologies which will feature Erik De Clercq’s ISAR/ICAR memories presentations from a variety of companies that ISAR member profile provide us with the technologies necessary to more Erik De Clercq efficiently and quantitatively perform our research. News items As always the meeting will prominently feature Ebola update: So near, yet so far networking opportunities which is the hallmark of ICAR 2015 Financial summary ICAR. From our sessions for Women in Science, our Young Investigator Reception, to all of the extended Calendar of future conferences coffee and lunch breaks, the ICAR provide numerous Job Opportunities opportunities to maintain long term friendships and The ISAR publications committee meet new scientists. I look forward to personally welcoming you to La Jolla and ICAR in just a couple of short and very busy months. 28th ICAR Corporate and Educational Sponsors. PLATINUM: Gilead Sciences. GOLD: Chimerix, GlaxoSmithKline. SILVER: Alios BioPharma, Biota Pharmaceuticals, Elsevier B.V., JCR Pharmaceutical Co. Ltd., Southern Research Institute. BRONZE: ACS Infectious Diseases, Bristol-Myers Squibb, ImQuest BioSciences, Medivir AB, Novira Therapeutics, PTC Therapeutics, Toyama Chemical Co. Ltd, University of Minnesota Center for Drug Design, Institute for Antiviral Research Utah State University, and XpressBio. Antiviral Research 1 January 2016 ISAR News Vol. 25 No. 3 Our meeting will commence this year with two when you are doing something you love and I must Keynote addresses. Heinz Feldmann will present on admit that I have truly enjoyed being able to regularly his work with Ebola and present important work and interact with such a fine group of scientists information about the recent outbreak in West Africa. from around the world to do good things (and avoid Richard Scheuermann from the J. Craig Venter bad things) for our Society and the annual conference. Institute will then speak on viral genomics and the I expect our recently established efforts on behalf predictive ability of genomic analysis. This year’s of Women in Science, Young Investigators, Career program also features two minisymposia which have Forum and the Ambassador Program will continue to been organized by Andrea Brancale, Bruno Canard, grow and flourish in the future. Much has been Erica Olmann Saphire, Rhonda Cardin and Graciela accomplished over the past couple of years and we Andrei. The first symposium will cover topics in still have much to do to assure that the Society structural biology while the second will focus on remains as strong and interactive as it is and that we DNA viruses. This year’s educational DD101 session continue to find ways to bring young investigators will highlight a cooperative program involving into leadership positions within the Society. So I academic institutions, not-for-profit organizations and especially hope that you will join us in La Jolla so we commercial partners in antiviral drug discovery to can celebrate the end of my Presidency and the facilitate the development of antiviral products. continued growth and evolution of the Society. As per my last message I also encourage you to See you in La Jolla! Bob Buckheit become involved in our Ambassador Program and introduce our Society and the Conference to someone UPDATE ON THE 29TH ICAR new. The Society and meeting are warm and open Program Committee (Mark Prichard) places for new scientists to present their research as well as initiate or continue to build important The International Society for Antiviral Research networks of colleagues to advance the development (ISAR) will host the 29th International Conference on of antiviral agents. Everyone that is a member Antiviral Research (29th ICAR) in La Jolla, certainly knows someone that would enjoy and California on Sunday April 17th through Thursday contribute greatly to the meeting, so why not reach April 21st 2016. This venue lies within the vibrant out and invite them to attend and relate to them your research community in the San Diego area and will experiences with ICAR. be held at the Hilton La Jolla Torrey Pines, 10950 I am excited to announce the results of our recent North Torrey Pines Road, La Jolla, California 92037. election. This year we had an excellent slate of Speakers at the meeting will present the latest candidates and all will certainly play roles in the scientific developments in antiviral research and will future of the Society and I’d like to than Phil Furman emphasize the interdisciplinary nature of this field. and the Nominations Committee for drafting such a The conference is designed specifically to provide great group of nominees. I am also pleased to say that opportunities for all participants to establish and we had a record voter turnout this year and the final maintain the close collaborative relationships among results confirmed how well respected all of the chemists, pharmacologists, and biologists that are candidates were viewed within the Society. Johan required for the discovery and development of Neyts was elected President Elect, Graciela Andrei effective antiviral therapies. It also serves to was re-elected as Secretary and Mike Bray, Andea stimulate innovative thinking on the drug Brancale and Kathie Seley-Radtke were elected to development process and provides specific events to seats on the Board of Directors. I look forward to welcome new scientists to our ranks to help them to working with all of the newly elected individuals as I establish successful careers. Attending this annual step into the role of Past-President and wish all of the meeting is important for all ISAR members as it new electees the best of luck in leading the Society serves to strengthen existing contacts and provides an over the next two years. th opportunity to add new contacts to their network by The 29 ICAR in La Jolla will be a very special meeting new scientists working in the field. one for me as I end my term as President of the The formal commencement of the 29th ICAR will Society. I am now two-thirds of the way through my start on April 17th 2016 at 4:00 PM and will be role as President-Elect, President and Past-President marked by two Keynote Speakers: (Please see below and in La Jolla I will hand over the reins of the for their photographs and biographies). Society to my highly capable successor José Esté of Barcelona. It’s hard to believe how fast time flies Antiviral Research 2 January 2016 ISAR News Vol. 25 No. 3 Heinz Feldmann, (NIH) will present his work on profit research organizations and commercial Ebola virus, starting with his research in Marburg, partners can drive the rapid develop of therapies Germany, where the first filovirus outbreak occurred for emerging infections. This interactive session in 1967, through the recent West African Ebola will highlight presentations by the following epidemic. He will also provide a look ahead: what's speakers: needed, what should be the goals of Ebola research, o Maaike Everts (University of Alabama at where do we go from here? Birmingham) Richard H. Scheuermann, (J. Craig Venter o David Cowfer (Gilead Sciences) Institute) will provide an address entitled: “Decoding o Bob Bostwick (Southern Research) Viral Genomics in the Next Generation Era”. The o Mark Denison (Vanderbilt University) availability of whole genome sequence data • Plenary presentations will also be provided by: combined with standard representations of virus o Pei-Yong Shi (University of Texas at phenotypic characteristics from large numbers of Galveston) viral isolates is allowing for extensive genotype- o Rob Jordan (Gilead Sciences) phenotype association studies that go well beyond traditional phylogenetic lineage tracing. In this The 29th ICAR will host a Diagnostic presentation he will demonstrate the use of statistical Technologies Workshop on the afternoon of genomics analysis to predict influenza virus evolution Tuesday April 19th. This special workshop will in the face of adaptive immunity and to identify novel present new technologies to help drive the genetic determinants of disease severity in development of effective new therapies for virus enterovirus D68. infections. Specifically, it will showcase rapid This year the meeting will feature the following diagnostic technologies that can be used to identify scientific sessions: viral infections in a timely manner to ensure that • The first short symposium will highlight recent patients can benefit from effective antiviral therapies. developments on the use of structural biology in More importantly, these technologies can maximize the discovery and development of antiviral drugs. the power of clinical trials by identifying subjects that The session is being organized by a trio of ISAR are infected with the virus of interest, yet remain free Prusoff Award winners: Andrea Brancale, from other common viral infections that could mask a Bruno Canard, and Erica Ollman Saphire and significant clinical response.
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