Safety data sheet Issue Date 14-Nov-2019 Revision Date 14-Nov-2019 Version 3
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1. Product identifier Product Name Propionaldehyde
Chemical Name CAS No EC No REACH Registration Number Propionaldehyde 123-38-6 204-623-0 01-2119456625-33-0001
Pure substance/mixture Substance
1.2. Relevant identified uses of the substance or mixture and uses advised against
Application Use: as an intermediate, strictly controlled conditions applies (exposure scenarios not required)
Uses advised against Not identified.
1.3. Details of the supplier of the safety data sheet Manufacturer
Perstorp Oxo AB SE-444 84 Stenungsund Sweden Tel. +46 303 728600 Fax. +46 303 728607 www.perstorp.com
E-mail address [email protected]
1.4. Emergency telephone number Europe (+)1 760 476 3961 (contract no: 334101)
United Kingdom (+)44 8 08 189 0979 (contract no: 334101)
SECTION 2: Hazards identification
2.1. Classification of the substance or mixture Classification according to Regulation (EC) No. 1272/2008 [CLP] Acute toxicity - Oral Category 4 - (H302) Acute toxicity - Inhalation (Vapours) Category 4 - (H332) Skin corrosion/irritation Category 2 - (H315) Serious eye damage/eye irritation Category 2 - (H319)* Specific target organ toxicity (single exposure) Category 3 - (H335) Flammable liquids Category 2 - (H225)
2.2. Label elements Symbols/Pictograms
Signal word
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Danger
Hazard statements H225 - Highly flammable liquid and vapour H332 - Harmful if inhaled H302 - Harmful if swallowed H319 - Causes serious eye irritation H315 - Causes skin irritation H335 - May cause respiratory irritation
Precautionary Statements P210 - Keep away from heat/sparks/open flames/hot surfaces. - No smoking P241 - Use explosion-proof electrical/ ventilating/ lighting/ equipment P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P312 - Call a POISON CENTER or doctor if you feel unwell P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P337 + P313 - If eye irritation persists: Get medical advice/attention
Contains: Propionaldehyde
2.3. Other hazards * The substance has a harmonised EU classification with Eye Irritation Cat 2. Test data have however shown that the damages were not reversible within 21 days which means that the substance should be regarded as a substance classified with Eye Irritation Cat 1.
SECTION 3: Composition/information on ingredients
3.1 Substances Chemical Name EC No CAS No REACH Registration Weight-% Classification according to Number Regulation (EC) No. 1272/2008 [CLP] Propionaldehyde 204-623-0 123-38-6 01-2119456625-33-0001 100 Flam. Liq. 2 (H225) Acute Tox. 4 (H302) Acute Tox. 4 (H332) Skin Irrit. 2 (H315) Eye Irrit. 2 (H319) STOT SE 3 (H335)
Full text of H- and EUH-phrases: see section 16
SECTION 4: First aid measures
4.1. Description of first aid measures
General advice Remove contaminated clothing and shoes. First aid personnel should pay attention to their own safety.
Inhalation Remove to fresh air. If breathing is irregular or stopped, administer artificial respiration. Keep victim warm and quiet. Seek immediate medical attention/advice.
Skin contact Immediately flush skin with water and rinse skin with soap and water for at least 5-10 minutes. Use lukewarm water if possible. Remove contaminated clothing and shoes. Get medical attention if redness does not disappear.
Eye contact Important! Immediately rinse cautiously with tempered water for at least 15 minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical attention.
Ingestion Clean mouth with water and drink plenty of water afterwards. Do NOT induce vomiting. Seek immediate medical attention/advice.
4.2. Most important symptoms and effects, both acute and delayed Inhalation: May cause irritation of the upper respiratory tract. Excessive inhalation of high concentrations may cause nausea,
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Page 2 / 10 EUGB - BE Propionaldehyde Revision Date 14-Nov-2019 ______vomiting, headache, and dizziness. Skin contact: May cause redness and swelling of the skin. Absorption of harmful amounts is not likely. Eye contact: Causes severe irritation with flood of tears and pain and strong redness and swelling of the eye. Risk of damage to the conjunctiva and cornea. Ingestion: May cause irritation of the mouth, throat, esophagus, and stomach including severe pain. Nausea, vomiting, diarrhea, dizziness or drowsiness, and headache may as well occur.
4.3. Indication of any immediate medical attention and special treatment needed Treat symptomatically.
SECTION 5: Firefighting measures
5.1. Extinguishing media Suitable extinguishing media Alcohol resistant foam. Carbon dioxide (CO2). Extinguishing powder.
Unsuitable extinguishing media High volume water jet. Do not use a solid water stream as it may scatter and spread fire.
5.2. Special hazards arising from the substance or mixture The substance is a flammable liquid and may form explosive air/vapour mixtures. Vapour is heavier than air and may accumulate in low areas and travel a considerable distance up to the source of ignition. When flames are extinguished, explosive re-ignition may occur.
Hazardous combustion products Carbon dioxide (CO2), Carbon monoxide (CO).
5.3. Advice for firefighters Wear self-contained breathing apparatus and protective suit.
Additional information Prevent fire extinguishing water from contaminating surface water or the ground water system. Cool containers with flooding quantities of water until well after fire is out.
SECTION 6: Accidental release measures
6.1. Personal precautions, protective equipment and emergency procedures The substance/product is registered with strictly controlled conditions as defined in Article 18(4) of Regulation (EC) No. 1907/2006 (REACH Regulation) and must therefore be handled as such. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Keep unprotected persons away. In case of major spill contact the rescue services. For emergency responders: Wear fully protective suit. Wear full face mask with filter for organic substances.
6.2. Environmental precautions Do not allow into any sewer, on the ground or into any body of water. Local authorities should be advised if significant spillages cannot be contained. See Section 12 for additional ecological information.
6.3. Methods and material for containment and cleaning up Methods for containment Prevent further leakage or spillage if safe to do so. Small spill Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Large spill Pump up the product into a spare container suitably labelled. Ground container and fittings.
Methods for cleaning up Clean contaminated surface thoroughly. Use clean non-sparking tools to collect absorbed material.
6.4. Reference to other sections See Section 7,8,13 for more information.
SECTION 7: Handling and storage
7.1. Precautions for safe handling Handle only under strictly controlled conditions in accordance with Regulation (EC) No. 1907/2006, Art. 18 (4). Comply with
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2014/34/EU concerning equipment and protective systems intended for use in potentially explosive atmospheres and, Directive 1999/92/EC regarding minimum requirements for improving the safety and health protection of workers potentially at risk from explosive atmospheres. Keep away from sources of ignition - No smoking. Take action to prevent static discharges.
General Hygiene Considerations Not applicable. No exposure expected.
7.2. Conditions for safe storage, including any incompatibilities Store under inert atmosphere, e.g. nitrogen pad. Keep in a cool place.
7.3. Specific end use(s) Not applicable.
SECTION 8: Exposure controls/personal protection
8.1. Control parameters Exposure Limits Keep personal exposure levels below Derived No Effect Level (DNEL) and national exposure limit values (if existing).
Derived No Effect Level (DNEL) - worker No DNEL values have been calculated since the product is an intermediate which must be handled according to strictly controlled conditions.
Derived No Effect Level (DNEL) - Consumer No DNEL values have been calculated since the product is an intermediate which must be handled according to strictly controlled conditions.
Predicted No Effect Concentration (PNEC) No PNEC values have been calculated since the product is an intermediate which must be handled according to strictly controlled conditions.
8.2. Exposure controls
Appropriate engineering controls Comply with 2014/34/EU concerning equipment and protective systems intended for use in potentially explosive atmospheres and, Directive 1999/92/EC regarding minimum requirements for improving the safety and health protection of workers potentially at risk from explosive atmospheres.
Individual protection measures, such as personal protective equipment Eye/face protection Tight sealing safety goggles. Hand Protection Wear protective butyl rubber gloves. Glove thickness. >0.7 mm. Ensure that the breakthrough time of the glove material is not exceeded. Refer to glove supplier for information on breakthrough time for specific gloves.
Skin and body protection Body protection must be chosen depending on activity and possible exposure, e.g. apron, chemical resistant boots, chemical-protection suit. Respiratory protection Suitable respiratory protection for lower concentrations or short-term exposure: Gas filter for gases/vapours of organic compounds (boiling point <65°C, e.g. EN 14387 Type AX) Suitable respiratory protection for higher concentrations or long-term exposure: Self-contained breathing apparatus.
Environmental exposure controls Not applicable. No exposure expected.
SECTION 9: Physical and chemical properties
9.1. Information on basic physical and chemical properties Appearance
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liquid colourless Odour Pungent Odour threshold 1 ppm
Property Value Remarks • Method pH ~6 Melting point / freezing point OPERATOR < 20 °C / 68 °F Boiling point / boiling range 47 °C / 117 °F OECD Test No. 103: Boiling Point Flash point < -20 °C / < -4 °F CC (closed cup) Evaporation rate No information available Flammability (solid, gas) Not applicable Explosive limits Upper explosive limits 21 % No information available Lower explosive limits 2.3 % No information available Vapour pressure 42 kPa (@25°C; SPARC)
Vapour density 2.0 @ Air = 1 Relative density 0.8 @20°C; ISO 2811-2 Water solubility 250 g/L OECD Test No. 105: Water Solubility Solubility(ies) No information available Partition coefficient 0.7 log PoW (@20°C; OECD 107) Partition Coefficient (n-octanol/water) Autoignition temperature 190 °C / 374 °F (ASTM E 659-78) Decomposition temperature Not applicable Kinematic viscosity No information available Dynamic viscosity No information available Explosive properties Not explosive. May form explosive mixtures with air Oxidising properties Not oxidising. Density No information available Bulk density No information available
9.2. Other information No information available.
SECTION 10: Stability and reactivity
10.1. Reactivity The substance is an aldehyde and may undergo reversible addition reactions such as hydration and hemiacetal formation, acetal formation, enamine formation and cyanohydrin formation, and irreversible addition reactions such as reduction by complex metal hydrides and addition of organometallic reagents. The substance may as well undergo other carbonyl group reactions such as reduction and oxidation.
10.2. Chemical stability In contact with air/oxygen the product will slowly form peroxides. The reaction is activated by light or catalyzed by salts of transition metals. Reacts with water or with the moisture in the air to form propionic acid.
10.3. Possibility of hazardous reactions Reacts with many compounds; Alcohols, Amines. Polymerisation may occur in presence of acids or caustics, leading to pressure build-up in closed systems. Contaminated organic fibrous materials may catch fire in contact with air.
10.4. Conditions to avoid Avoid contact with heat, sparks, open flame, static discharge or any other sources of ignition. When finely distributed, self-ignition is possible.
10.5. Incompatible materials Strong acids, Strong bases, Strong reducing agents
10.6. Hazardous decomposition products None known.
SECTION 11: Toxicological information
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11.1. Information on toxicological effects
Information on likely routes of exposure Inhalation, Dermal.
Symptoms related to the physical, chemical and toxicological characteristics See Section 4 for more information.
Numerical measures of toxicity
Acute toxicity Harmful if swallowed or if inhaled.
Propionaldehyde (123-38-6) Method Species Exposure route Effective dose Remarks OECD Test No. 401: Acute Rat Oral 1690 LD50 (lethal dose) Oral Toxicity mg/kg OECD Test No. 402: Acute rabbit Dermal 2460 LD50 (lethal dose) Dermal Toxicity mg/kg OECD Test No. 403: Acute Rat Inhalation >4.6 Inhalation LC50 - 4 Inhalation Toxicity hour - vapour - mg/L
Skin corrosion/irritation May cause irritation.
Propionaldehyde (123-38-6) Method Species Exposure route Results: OECD Test No. 404: Acute Dermal rabbit Dermal Non-irritating to the skin Irritation/Corrosion
Serious eye damage/eye irritation Risk of serious damage to eyes.
Propionaldehyde (123-38-6) Method Species Exposure route Results: OECD Test No. 405: Acute Eye rabbit Eye Causes serious eye damage Irritation/Corrosion
Respiratory or skin sensitisation Not a skin sensitiser.
Propionaldehyde (123-38-6) Method Species Exposure route Results: OECD Test No. 429: Skin Mouse Skin Not a skin sensitiser Sensitisation: Local Lymph Node Assay
Germ cell mutagenicity Not mutagenic.
Propionaldehyde (123-38-6) Method Species Results: OECD Test No. 471: Bacterial Reverse in vitro Negative Mutation Test OECD Test No. 476: In vitro Mammalian Cell in vitro Positive Gene Mutation Test OECD Test No. 479: Genetic Toxicology: In in vitro Negative vitro Sister Chromatid Exchange Assay in
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Mammalian Cells In vitro Mammalian Chromosome Aberration in vitro Negative Test OECD Test No. 482: Genetic Toxicology: DNA in vitro Negative Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells in vitro OECD Test No. 474: Mammalian Erythrocyte in vivo Negative Micronucleus Test
Carcinogenicity No information available.
Reproductive toxicity No indication of reproductive toxicity according to OECD guideline 422 screening test.
Propionaldehyde (123-38-6) Method Species Exposure route Effective dose Remarks OECD Test No. 422: Rat Inhalation >=1500 P, ppm NOEC No Combined Repeated Dose indication of Toxicity Study with the reproductive toxicity Reproduction/Developmental according to OECD Toxicity Screening Test guideline 422 screening test.
STOT - single exposure Irritating to respiratory system.
STOT - repeated exposure
Propionaldehyde (123-38-6) Method Species Exposure route Effective dose Remarks OECD Test No. 422: Rat Inhalation 362 NOAEC mg/m3 Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test
Aspiration hazard No hazard identified.
SECTION 12: Ecological information
12.1. Toxicity Harmful to aquatic life.
Propionaldehyde (123-38-6) Method Species Exposure route Effective dose Exposure time Remarks Not defined Pimephales Freshwater 14 96h LC50 (lethal promelas concentration) mg/l Regulation (EC) No. Daphnia magna Freshwater 89 48h LC50 (lethal 440/2008, Annex, C.2 concentration) mg/l DIN 38412 Scenedesmus Freshwater 260 72h EC50 (effective subspicatus concentration) mg/l OECD Test No. 204: Fish, Poecilia reticulata Freshwater 15 14d LC50 (lethal Prolonged Toxicity Test: concentration) mg/l 14-Day Study
12.2. Persistence and degradability Readily biodegradable.
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Propionaldehyde (123-38-6) Method Value Exposure time Results: OECD Test No. 301C: Ready >91% 28d Readily biodegradable Biodegradability: Modified MITI Test (I) (TG 301 C)
12.3. Bioaccumulative potential No bioaccumulation potential.
Chemical Name Partition coefficient Bioconcentration factor (BCF) Propionaldehyde 0.7
12.4. Mobility in soil The product is not expected to adsorb to a high degree to suspended solids and sediment based upon the log Koc which indicates a moderate to high mobility in soil.
Chemical Name Log Koc Propionaldehyde -0.007
12.5. Results of PBT and vPvB assessment This substance does not meet the criteria for classification as PBT or vPvB
12.6. Other adverse effects The substance may contribute the formation of ground level ozone.
SECTION 13: Disposal considerations
13.1. Waste treatment methods Waste from residues/unused products This material and its container must be disposed of as hazardous waste. Incinerate at a licensed installation.
Contaminated packaging Contaminated packaging materials must be disposed of in the same manner as the product.
Waste codes / waste designations according to EWC / AVV Waste from residues/unused products: 16 03 05*.
Other Information Waste codes should be assigned by the user based on the application for which the product was used.
SECTION 14: Transport information
ADR Road transport 14.1 UN number UN1275 14.2 UN proper shipping name Propionaldehyde Proper Shipping Description UN1275, Propionaldehyde, 3, II, (D/E) 14.3 Transport hazard class(es) 3 Subsidiary class - 14.4 Packing Group II 14.5 Environmental hazard Not applicable 14.6 Special precautions for user None Tunnel restriction code (D/E) Limited quantity (LQ) 1 L ADR Hazard Id (Kemmler 33 Number)
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RID Rail transport 14.1 UN number UN1275 14.2 UN proper shipping name Propionaldehyde Proper Shipping Description UN1275, Propionaldehyde, 3, II 14.3 Transport hazard class(es) 3 Subsidiary hazard class - 14.4 Packing Group II 14.5 Environmental hazard Not applicable 14.6 Special precautions for user None
IMDG Sea transport 14.1 UN number UN1275 14.2 UN proper shipping name Propionaldehyde Proper Shipping Description UN1275, Propionaldehyde, 3, II, (-20°C c.c.) 14.3 Transport hazard class(es) 3 14.4 Packing Group II 14.5 Marine pollutant Not applicable 14.6 Special precautions for user None EmS-No F-E, S-D Limited quantity (LQ) 1 L 14.7 Transport in bulk according Y, S/P,3,2,G,T4,N to Annex II of MARPOL 73/78 and the IBC Code
IATA Air transport 14.1 UN number UN1275 14.2 UN proper shipping name Propionaldehyde 14.3 Transport hazard class(es) 3 14.4 Packing Group II Proper Shipping Description UN1275, Propionaldehyde, 3, II 14.5 Environmental hazard Not applicable 14.6 Special precautions for user None Limited quantity (LQ) 1 L ERG Code 3H
SECTION 15: Regulatory information
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture International Regulations Not applicable.
European Union
Council Directive 2012/18/EU on the control of major-accident hazards involving dangerous substances. Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work Comply with 2014/34/EU concerning equipment and protective systems intended for use in potentially explosive atmospheres and, Directive 1999/92/EC regarding minimum requirements for improving the safety and health protection of workers potentially at risk from explosive atmospheres.
France
Occupational Illnesses (R-463-3, France) ; Aldehydes
Germany Water hazard class (WGK) slightly hazardous to water (WGK 1)
15.2. Chemical safety assessment No assessment required (industrial use as intermediate under strictly controlled conditions).
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SECTION 16: Other information
Key or legend to abbreviations and acronyms used in the safety data sheet
Full text of H-Statements referred to under section 3 H225 - Highly flammable liquid and vapour H302 - Harmful if swallowed H315 - Causes skin irritation H319 - Causes serious eye irritation H332 - Harmful if inhaled H335 - May cause respiratory irritation
Issue Date 14-Nov-2019
Revision Date 14-Nov-2019
Revision Note The SDS has been reviewed but no relevant changes found
This safety data sheet complies with the requirements of: Regulation (EC) No. 1907/2006, COMMISSION REGULATION (EU) No. 830/2015 of 20 May 2015.
Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.
End of Safety Data Sheet
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