Intended as original research paper for Forensic Science International: Genetics The HIrisPlex-S system for eye, hair and skin colour prediction from DNA: Introduction and forensic developmental validation Lakshmi Chaitanya1, Krystal Breslin2, Sofia Zuñiga3, Laura Wirken4, Ewelina Pośpiech5, Magdalena Kukla-Bartoszek6, Titia Sijen3, Peter de Knijff4, Fan Liu1,7,8, Wojciech Branicki5,9, Manfred Kayser1*,#, Susan Walsh2*,# 1 Department of Genetic Identification, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands 2 Department of Biology, Indiana University Purdue University Indianapolis (IUPUI), Indiana, USA 3 Division Biological Traces, Netherlands Forensic Institute, The Hague, The Netherlands 4 Forensic Laboratory for DNA Research, Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands 5 Malopolska Centre of Biotechnology, Jagiellonian University, Kraków, Poland 6 Faculty of Biochemistry, Biophysics and Biotechnology of the Jagiellonian University, Kraków, Poland 7 Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China 8 University of Chinese Academy of Sciences, Beijing, China 9 Central Forensic Laboratory of the Police, Warsaw, Poland # these authors contributed equally to this work * Corresponding authors SW: phone +1-317-274-0593, e-mail
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