Rotavirus - Adenovirus Astrovirus - Norovirus

Rotavirus, Adenovirus and Astrovirus are the agents most frequently responsible for gas- troenteritis in infant and youth populations, as well as occasionally in adults. They are trans- mitted faeco-orally and their main symptoms are watery diarrhoea and vomiting.

The concern for global public health cau- sed by Noroviruses has increased in recent years due to sporadic outbreaNs of signiÀcant morbidity and mortality. There are frequent outbreaks in schools, hospitals, cruise ships and other semi-closed institutions.

Noroviruses are the main cause of gastroenteritis epidemics in the United States (approximately 90% of outbreaks of non-bacterial gastroenteritis). The symptoms associated with Novovirus infections are typical of gastroenteritis: vomiting, watery diarrhoea and abdominal cramps.

Enteric viruses have been recognised as the most important aetiological agents behind acute diarrhoea, the principal cause of mortality in many countries. SpeciÀcally, the four categories of viruses considered to be the most clinically relevant are the Group A Rotavirus, Adenovirus, Astrovirus and Norovirus. They give rise to co-infections in 46% of children with acute diarrhoea.

The new CERTEST combined test for Rotavirus, Adenovirus, Astrovirus and Norovirus means the four main enteric vi- ruses causing non-bacterial gastroenteritis can be simultaneously detected in stool samples using just a single test which is both rapid and accurate.

folleto ingles rotavirus -adenovirus- astrovirus.indd 1 14/07/2014 20:50:55 Test procedure

Cut the end of the cap and

 dispense exactly 4 drops into the “A” circular window marked with an arrow.

Unscrew the cap Close the tube with the diluent step and use the stick step and stool sample. Shake the step 1 to pick up 2 tube in order to assure good 3 the sample. sample dispersion. 

Wait for coloured bands to Dispense exactly 4 drops into appear. step 7 the “D” circular window step Read the result at 10 minutes marked with an arrow. 4

step Dispense exactly 4 drops into 6 the “B” circular window marked with an arrow.

10 min.

step

 5 

Dispense exactly 4 drops into the “C” circular window marked with an arrow.

Interpretation of the results

                                   

                                   

SENSITIVITY SPECIFICITY PPV NPV Rotavirus >99% 98% >94% >99% Adenovirus >99% >99% >99% >99% Astrovirus >94% >99% >99% >92% Norovirus >99% >99% >99% >99% FRG86EN

Pol. Ind. Río Gállego II oCalle J o Nº 1 50840 o San Mateo de Gállego o Zaragoza o Spain Tel.: +34 976 520 354 www.certest.es

folleto ingles rotavirus -adenovirus- astrovirus.indd 2 14/07/2014 20:51:08