Anti-CTH (Aa 250-350) Polyclonal Antibody (DPABH-26846) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-CTH (aa 250-350) polyclonal antibody (DPABH-26846) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.

Immunogen Synthetic peptide conjugated to KLH derived from within residues 250 - 350 of Human Cystathionase.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB, ICC/IF

Format Liquid

Size 100 μg

Buffer pH: 7.40; Constituent: PBS

Preservative 0.02% Sodium Azide

Storage Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

GENE INFORMATION

Gene Name CTH cystathionase (cystathionine gamma-lyase) [ Homo sapiens ]

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Synonyms CTH; cystathionase (cystathionine gamma-lyase); cystathionine gamma-lyase; gamma- cystathionase; homoserine deaminase; cysteine desulfhydrase; homoserine dehydratase; cysteine-protein sulfhydrase;

Entrez Gene ID 1491

Protein Refseq NP_001177392.1

UniProt ID P32929

Pathway Biosynthesis of amino acids; Cysteine and methionine metabolism; Cysteine biosynthesis, homocysteine + serine => cysteine; Cysteine formation from homocysteine

Function L-cysteine desulfhydrase activity; L-cystine L-cysteine-lyase (deaminating); calmodulin binding; carbon-sulfur lyase activity

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]