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CUA Guideline: the Workup and Management of Azoospermic Males
Originalcua guideline research CUA Guideline: The workup and management of azoospermic males Keith Jarvi, MD, FRCSC;* Kirk Lo, MD, FRCSC;* Ethan Grober, MD;* Victor Mak, MD, FRCSC;* Anthony Fischer, MD, FRCSC;¥ John Grantmyre, MD, FRCSC;± Armand Zini, MD, FRCSC;+ Peter Chan, MD, FRCSC;+ Genevieve Patry, MD, FRCSC;£ Victor Chow, MD, FRCSC;§ Trustin Domes, MD, FRCSC# *Department of Urology, Mount Sinai Hospital, University of Toronto, Toronto, ON; ¥Division of Urology, McMaster University, Hamilton, ON; ±Department of Urology, Dalhousie University, Halifax, NS; +Division of Urology, McGill University Health Centre, Montreal, QC; £Hôtel-Dieu De Lévis, Lévis, QC; §Department of Urologic Sciences, University of British Columbia, Vancouver, BC; #Saskatoon Health Region, Saskatoon, SK Cite as: Can Urol Assoc J 2015;9(7-8):229-35. http://dx.doi.org/10.5489/cuaj.3209 A further group of men have a failure to ejaculate. These Published online August 10, 2015. may be men with spinal cord injury, psychogenic failure to ejaculate, or neurological damage (sympathetic nerve committee was established at the request of the damage from, for example, a retroperitoneal lymph node Canadian Urological Association to develop guide- dissection). A lines for the investigation and management of azo- To understand the management of azoospermia, it is ospermia. Members of the committee, all of whom have important to also understand the role of assisted reproduc- special expertise in the investigation and management of tive technologies (ARTs) (i.e., in-vitro fertilization) in the male infertility, were chosen from different communities treatment of azoospermia. Since the 1970s, breakthroughs across Canada. The members represent different practices in the ARTs have allowed us to offer potentially successful in different communities. -
Chronic Pelvic Pain Syndrome in Men
Chronic Pelvic Pain Syndrome in Men Diagram of the male genital tract showing the pelvic floor anatomy and how it is linked to the urinary tract with the urethra passing through it (external urethral sphincter). The pelvic floor therefore helps control how we pass water (urinate). (See resources at end for links to images of pelvic floor muscles and prostate.) SUMMARY Chronic pelvic pain syndrome (CPPS) and chronic prostatitis (CP) in men are often terms used to describe a condition which causes pain in the lower pelvic region of men. Symptoms are thought to come from the prostate gland or increased muscle tension around the pelvic floor. Our experience at Unity indicates that ¾ (75%) of men will have a significant improvement in their symptoms, with best results achieved by: 1) Ruling out underlying infection and excluding cancer in those who are worried about these being the cause 2) Having a detailed discussion so that you understand the complex mechanisms which can cause pelvic pain 3) Some treatments including alpha blockers, antibiotics, and sometimes painkillers 4) Pelvic floor muscle relaxation techniques 5) Psychological support/therapy in order to reduce pelvic floor muscle tension and improve strategies for coping with the pain, help you address your underlying worries and concerns and identify and reduce possible sources of stress. Vs3 31/03/2020 1 What is Chronic Pelvic Pain Syndrome? Chronic pelvic pain syndrome (CPPS) can occur in both men and women. It is sometimes also called chronic prostatitis (CP) in men. This leaflet deals with CPPS in men. CPPS/CP is an ongoing (persistent or recurrent > 3 of the last 6 months) discomfort or pain that you feel in your lower pelvic region - mainly at the base or tip of your penis, and/or your testicles and/or around your back passage (anus) for which no cause has been found. -
World Journal of Pharmaceutical and Life Sciences
wjpls, 2017, Vol. 3, Issue 8, 66-68 Review Article ISSN 2454-2229 Farman . World Journal of Pharmaceutical World Journal and Lifeof Pharmaceutical Sciences and Life Sciences WJPLS www.wjpls.org SJIF Impact Factor: 4.223 ONE TOO MANY- POLYORCHIDISM A RARE CASE REPORT AND REVIEW OF LITERATURE Dr. Farman Ali* India. *Corresponding Author: Dr. Farman Ali India. Email ID: [email protected], Article Received on 12/08/2017 Article Revised on 03/09/2017 Article Accepted on 24/09/2017 ABSTRACT Polyorchidism is the incidence of more than two testicles in a male. It is a rare congenital anomaly involving the abnormal division of the genital ridge longitudinally or transversely, mainly occurring in the scrotum. Triorchidism(presence of 3 testes) is the most common occurrence of this condition. They mostly occur on the left side. There have been only 140-200 pathological cases that are published in world journal literature, out of which only a few cases have been reported in India. A rare case was reported of a 20 year old man with polyorchidism presenting with an inguinal hernia, describing the clinical features, it's surgical findings and a review of the literature. The most common sites are: Scrotal(66%), inguinal(25%), and abdominal(9%). This condition is mostly asymptomatic but may commonly present with features like maldescent(40%), hernia(30%), torsion(15%), hydrocoele(9%) and malignancy(6%). Spermatogenesis may be normal only in 50% of cases. If symptoms present, they may be scrotal pain, swelling and infertility. High accuracy of pre-operative ultrasound evaluation of scrotal mass differentiates this benign entity from ominous abnormalities and prevents unnecessary surgical exploration of sonographically normal, uncomplicated and orthotopic supernumerary testes. -
5Α-Reductase Deficiency, 173, 175 Acrosomal Response to Ionophore
Cambridge University Press 978-0-521-88109-8 - Surgical and Medical Management of Male Infertility Marc Goldstein and Peter N. Schlegel Index More information Index 5α-reductase deficiency,173 , 175 antioxidant therapy, 187–9 genetic testing, 20–2, children, 271–2 acrosomal response to ionophore carnitine, 188 162 experimental methods, 272 challenge (ARIC) score, carotenoids, 188 preoperative preparation, gonadal protection with 15 folate, 188 162–3 hormonal suppression, 271 acrosome, 4–5 lycopene, 188 treatment considerations, gonadal shielding with acrosome reaction assays, N-acetylcysteine (NAC), 188 163 radiotherapy, 271 14–15 selenium, 189 obstructive, 19, 61–2, nursing issues, 326–7 acupuncture, 190 vitamin C, 187–8 See also epididymal sperm sperm banking, 271, 281–4 adenohypophysis, 1 vitamin E, 188 aspiration fertility treatment after cancer adolescents. See also pediatric anti-retroviral drugs, 289 evaluation, 100 therapy, 272–3 issues antisperm antibodies, 234, sperm retrieval, 101–3 pediatric, 264 fertility preservation issues, See also autoimmunity to testicular biopsy, 61 treatment effects on 271 spermatozoa 27–8 azoospermic factor (AZF) region, fertility, 269–70, 285, varicocele, 262–3 cystic fibrosis and,29–30 5, 21 See also chemotherapy; agenesis, seminal vesicles, 48–50 effects on fertility,28–9 AZFa, 20 radiotherapy aging, 2 routine testing for, 33, 234 AZFb, 20 anatomical obstruction, 269 AIDS, 197–8 antral follicle count, 222 AZFc, 20, 22 hormonal and gonadotoxic alcohol abuse, 9, 189 anxiety, sexual dysfunction and, -
How to Investigate Azoospermia in Stallions
NON-PREGNANT MARE AND STALLION How to Investigate Azoospermia in Stallions Terry L. Blanchard, DVM, MS, Diplomate ACT; Steven P. Brinsko, DVM, MS, PhD, Diplomate ACT; Dickson D. Varner, DVM, MS, Diplomate ACT; and Charles C. Love, DVM, PhD, Diplomate ACT Authors’ address: Department of Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station, Texas 77843-4475; e-mail: stalliondoc@ gmail.com. © 2009 AAEP. 1. Introduction did not ejaculate.3 A number of reports describe In a review of ejaculatory dysfunction, McDonnell1 therapy indicated for ejaculation failure, but they reported that ϳ25% of stallions referred to a fertility are not the subject of this report. Briefly, they in- clinic had evidence of ejaculatory problems. The clude breeding and/or pharmacological management vast majority of cases were anejaculatory (failure to to increase sexual stimulation before and during the ejaculate). Less than 1% of horses in that survey breeding process, treatment and/or breeding man- were truly azoospermic (i.e., ejaculated seminal flu- agement to minimize potential musculoskeletal pain ids devoid of sperm). Failure to ejaculate sperm that could interrupt the emission and ejaculatory can be a troublesome problem that requires accurate process, and pharmacologic manipulation to lower diagnosis, determination of prognosis for correction the threshold to emission and ejaculation.1–3 Tech- (sometimes necessitating retirement as a breeding niques used to manage repeated ejaculatory failure stallion), and arduous treatment and/or breeding can be arduous and time consuming, and they are management to correct.2,3 Figure 1 represents an reviewed by Varner et al.3 attempt at a schematic overview of an approach to When breeding behavior and apparent ejaculation diagnosis of lack of sperm in ejaculates. -
Massachusetts Birth Defects 2002-2003
Massachusetts Birth Defects 2002-2003 Massachusetts Birth Defects Monitoring Program Bureau of Family Health and Nutrition Massachusetts Department of Public Health January 2008 Massachusetts Birth Defects 2002-2003 Deval L. Patrick, Governor Timothy P. Murray, Lieutenant Governor JudyAnn Bigby, MD, Secretary, Executive Office of Health and Human Services John Auerbach, Commissioner, Massachusetts Department of Public Health Sally Fogerty, Director, Bureau of Family Health and Nutrition Marlene Anderka, Director, Massachusetts Center for Birth Defects Research and Prevention Linda Casey, Administrative Director, Massachusetts Center for Birth Defects Research and Prevention Cathleen Higgins, Birth Defects Surveillance Coordinator Massachusetts Department of Public Health 617-624-5510 January 2008 Acknowledgements This report was prepared by the staff of the Massachusetts Center for Birth Defects Research and Prevention (MCBDRP) including: Marlene Anderka, Linda Baptiste, Elizabeth Bingay, Joe Burgio, Linda Casey, Xiangmei Gu, Cathleen Higgins, Angela Lin, Rebecca Lovering, and Na Wang. Data in this report have been collected through the efforts of the field staff of the MCBDRP including: Roberta Aucoin, Dorothy Cichonski, Daniel Sexton, Marie-Noel Westgate and Susan Winship. We would like to acknowledge the following individuals for their time and commitment to supporting our efforts in improving the MCBDRP. Lewis Holmes, MD, Massachusetts General Hospital Carol Louik, ScD, Slone Epidemiology Center, Boston University Allen Mitchell, -
Ejaculation Problems3 9
1 6 Fact Sheet 7 12 2 8 11 Ejaculation Problems3 9 4 10 5 What is ejaculation? 1 Bladder 2 Vas deferens Ejaculation is the release of semen from the penis 3 Urethra at orgasm (sexual climax). When a man is sexually 1 stimulated, the brain sends signals to the genital 6 4 Penis area through nerves in the spinal cord to make the 5 Scrotum 7 12 pelvic muscles contract. 2 8 6 Seminal vesicle 11 7 Rectum At orgasm, waves of muscle contractions transport 3 the sperm, with a small amount of fluid, from the 8 Prostate gland testes through to the vas deferens. The seminal 9 9 Epididymis vesicles and prostate contribute extra fluid to 4 10 Testicle protect the sperm. 10 11 Cowper’s gland 5 This mixture of sperm and fluid (semen) travels 12 Ejaculatory duct along the urethra to the tip of the penis where it is ejaculated (released). What are ejaculation problems? More details about premature ejaculation can be found in a separate1 Bladder Andrology Australia fact Men can experience different kinds of ejaculation sheet. 2 Vas deferens problems, including: 3 Urethra The other ejaculation4 Penis problems are less common • premature ejaculation than premature ejaculation5 Scrotum but can also cause distress for the man and his partner. • retrograde ejaculation 6 Seminal vesicle 7 Rectum • delayed ejaculation (or no ejaculation) What causes ejaculation problems? 8 Prostate gland • painful ejaculation. Ejaculation problems9 Epididymis can have a variety of 10 Testicle How common are ejaculation causes, both physical and psychological. Physical causes include11 Cowper’s some gland illnesses such problems? as diabetes, some 12typesEjaculatory of surgery duct or trauma, some types of inflammation or infection, certain Premature ejaculation is the most common male medicines, and chemical imbalances in the brain sexual problem and affects men of all ages. -
Aspermia: a Review of Etiology and Treatment Donghua Xie1,2, Boris Klopukh1,2, Guy M Nehrenz1 and Edward Gheiler1,2*
ISSN: 2469-5742 Xie et al. Int Arch Urol Complic 2017, 3:023 DOI: 10.23937/2469-5742/1510023 Volume 3 | Issue 1 International Archives of Open Access Urology and Complications REVIEW ARTICLE Aspermia: A Review of Etiology and Treatment Donghua Xie1,2, Boris Klopukh1,2, Guy M Nehrenz1 and Edward Gheiler1,2* 1Nova Southeastern University, Fort Lauderdale, USA 2Urological Research Network, Hialeah, USA *Corresponding author: Edward Gheiler, MD, FACS, Urological Research Network, 2140 W. 68th Street, 200 Hialeah, FL 33016, Tel: 305-822-7227, Fax: 305-827-6333, USA, E-mail: [email protected] and obstructive aspermia. Hormonal levels may be Abstract impaired in case of spermatogenesis alteration, which is Aspermia is the complete lack of semen with ejaculation, not necessary for some cases of aspermia. In a study of which is associated with infertility. Many different causes were reported such as infection, congenital disorder, medication, 126 males with aspermia who underwent genitography retrograde ejaculation, iatrogenic aspemia, and so on. The and biopsy of the testes, a correlation was revealed main treatments based on these etiologies include anti-in- between the blood follitropine content and the degree fection, discontinuing medication, artificial inseminization, in- of spermatogenesis inhibition in testicular aspermia. tracytoplasmic sperm injection (ICSI), in vitro fertilization, and reconstructive surgery. Some outcomes were promising even Testosterone excreted in the urine and circulating in though the case number was limited in most studies. For men blood plasma is reduced by more than three times in whose infertility is linked to genetic conditions, it is very difficult cases of testicular aspermia, while the plasma estradiol to predict the potential effects on their offspring. -
Ultrasound of the Scrotum
Ultrasound of scrotum 21.06.2011 12:42 1 EFSUMB – European Course Book Editor: Christoph F. Dietrich Ultrasound of the scrotum Paul S. Sidhu, Boris Brkljacic2, Lorenzo E. Derchi3 2Medical School, University of Zagreb, 3Department of Radiology, University of Genoa Corresponding author: Paul S. Sidhu BSc MBBS MRCP FRCR DTM&H Consultant Radiologist and Senior Lecturer King‟s College London Department of Radiology King‟s College Hospital Denmark Hill London SE5 9RS United Kingdom Tel: ++44 (0) 20 3299 3063 Fax: ++44 (0) 20 3299 3157 E-mail: [email protected] Ultrasound of scrotum 21.06.2011 12:42 2 Content Content ................................................................................................................................................. 2 Introduction .......................................................................................................................................... 3 Sonographic examination technique .................................................................................................... 3 Gross Anatomy..................................................................................................................................... 4 Embryology ...................................................................................................................................... 4 Scrotal sac and testicular anatomy ................................................................................................... 4 Vascular anatomy ............................................................................................................................ -
Male Sexual Dysfunction and Infertility Associated with Neurological Disorders Mikkel Fode University of Copenhagen
Florida International University FIU Digital Commons Department of Psychology College of Arts, Sciences & Education 1-2012 Male sexual dysfunction and infertility associated with neurological disorders Mikkel Fode University of Copenhagen Sheila Krogh-Jespersen Department of Psychology, Florida International University Nancy L. Beckett University of Miami Dana A. Ohl University of Michigan Charles M. Lynn University of Miami See next page for additional authors Follow this and additional works at: https://digitalcommons.fiu.edu/psychology_fac Part of the Psychology Commons Recommended Citation Asian Journal of Andrology (2012) 14, 61–68; doi:10.1038/aja.2011.70; This work is brought to you for free and open access by the College of Arts, Sciences & Education at FIU Digital Commons. It has been accepted for inclusion in Department of Psychology by an authorized administrator of FIU Digital Commons. For more information, please contact [email protected]. Authors Mikkel Fode, Sheila Krogh-Jespersen, Nancy L. Beckett, Dana A. Ohl, Charles M. Lynn, and Jens Sønksen This article is available at FIU Digital Commons: https://digitalcommons.fiu.edu/psychology_fac/5 Asian Journal of Andrology (2012) 14, 61–68 ß 2012 AJA, SIMM & SJTU. All rights reserved 1008-682X/12 $32.00 www.nature.com/aja REVIEW Male sexual dysfunction and infertility associated with neurological disorders Mikkel Fode1, Sheila Krogh-Jespersen2, Nancy L Brackett3, Dana A Ohl4, Charles M Lynne5 and Jens Sønksen1 Normal sexual and reproductive functions depend largely on neurological mechanisms. Neurological defects in men can cause infertility through erectile dysfunction, ejaculatory dysfunction and semen abnormalities. Among the major conditions contributing to these symptoms are pelvic and retroperitoneal surgery, diabetes, congenital spinal abnormalities, multiple sclerosis and spinal cord injury. -
Syndromic Aspects of Testicular Carcinoma
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by University of Groningen University of Groningen Syndromic aspects of testicular carcinoma Lutke-Holzik, MF; Sijmons, RH; Sleijfer, DT; Sonneveld, DJA; Hoekstra-Weebers, JEHM; van Echten-Arends, J; Hoekstra, HJ Published in: Cancer DOI: 10.1002/cncr.11155 IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2003 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Lutke-Holzik, MF., Sijmons, RH., Sleijfer, DT., Sonneveld, DJA., Hoekstra-Weebers, JEHM., van Echten- Arends, J., & Hoekstra, HJ. (2003). Syndromic aspects of testicular carcinoma. Cancer, 97(4), 984-992. https://doi.org/10.1002/cncr.11155 Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date: 12-11-2019 984 Syndromic Aspects of Testicular Carcinoma 1 Martijn F. -
Sex and the Prostate
Sex and the Prostate Seek Help! Erection problems aren’t ‘all in the mind’. One quarter of men treated for localised prostate cancer with radiotherapy can experience erection problems. If you suffer from prostate disease and are concerned about how this could affect your relationship with your partner, seek help. Don’t worry about talking to your doctor or nurse about your sex life – they want to help and they understand that it is important to you – it’s natural. This leaflet is for men with prostate disease and their partners, who may want to find out more about sexual problems so that they can continue to enjoy or, indeed, return to an intimate and fulfilling sex life. Sex and the prostate – two ‘intimate’ subjects At whatever stage in life, sex is an Prostate Bladder important part of an intimate and happy relationship for most couples. A disappointing or unfulfilling sex life can often damage a relationship, leaving either partner with a feeling of loneliness, insecurity and often too embarrassed to seek help and/or to start a new relationship. Although not typically described as a sexual problem, prostate disease and particularly its treatment, can be linked to, or be the cause of sexual problems in men. This booklet aims to explain some of the main reasons for this. The prostate gland is part of the male genito-urinary system. It is a small organ that lies just below a man's bladder. It surrounds the urethra, the tube that carries urine from the bladder out of the body through the penis.