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NIDA Drug Supply Program Catalog, 25Th Edition

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NIDA Drug Supply Program Catalog, 25Th Edition RESEARCH RESOURCES DRUG SUPPLY PROGRAM CATALOG 25TH EDITION MAY 2016 CHEMISTRY AND PHARMACEUTICS BRANCH DIVISION OF THERAPEUTICS AND MEDICAL CONSEQUENCES NATIONAL INSTITUTE ON DRUG ABUSE NATIONAL INSTITUTES OF HEALTH DEPARTMENT OF HEALTH AND HUMAN SERVICES 6001 EXECUTIVE BOULEVARD ROCKVILLE, MARYLAND 20852 160524 On the cover: CPK rendering of nalfurafine. TABLE OF CONTENTS A. Introduction ................................................................................................1 B. NIDA Drug Supply Program (DSP) Ordering Guidelines ..........................3 C. Drug Request Checklist .............................................................................8 D. Sample DEA Order Form 222 ....................................................................9 E. Supply & Analysis of Standard Solutions of Δ9-THC ..............................10 F. Alternate Sources for Peptides ...............................................................11 G. Instructions for Analytical Services .........................................................12 H. X-Ray Diffraction Analysis of Compounds .............................................13 I. Nicotine Research Cigarettes Drug Supply Program .............................16 J. Ordering Guidelines for Nicotine Research Cigarettes (NRCs)..............18 K. Ordering Guidelines for Marijuana and Marijuana Cigarettes ................21 L. Important Addresses, Telephone & Fax Numbers ..................................24 M. Available Drugs, Compounds, and Dosage Forms ..............................25 1. New Compounds.................................................................................27 2. Cannabinoids.......................................................................................29 • Allosteric Modulators .....................................................................29 • Cannabichromene Class ................................................................29 • Cannabicyclohexanol Class ...........................................................29 • Cannabidiol Class ...........................................................................30 • Cannabigerol Class ........................................................................30 • Cannabinol Class ............................................................................30 • Enzyme Inhibitors ...........................................................................31 • Fatty Acid Derivatives (Anandamides) ...........................................31 • Fatty Acid Derivatives (Arachidonyl amides) .................................32 • Fatty Acid Derivatives (Arachidonyl esters)...................................32 • Fatty Acid Derivatives (Palmitoyl amides) .....................................33 • Indole Analogs & Related Compounds..........................................33 NIDA Research Resources Drug Supply Program i • Indole, Alkylnaphthoyl Class ..........................................................34 • Precursors, Biosynthetic ................................................................36 • Precursors, Synthetic .....................................................................37 • Pyrazole Class ................................................................................37 • Tetrahydrocannabinol Class...........................................................38 • Dosage Form: Stock Solutions ......................................................46 3. Dissociatives .......................................................................................47 • Dexoxadrol Class ............................................................................47 • Phencyclidine Class .......................................................................47 4. Hallucinogens......................................................................................57 • Amphetamine Class........................................................................57 • Ergot Alkaloids................................................................................62 • Ibogaine Class ................................................................................63 • Methamphetamine Class ...............................................................64 • Miscellaneous .................................................................................66 • Phenethylamine Class ....................................................................66 • Tryptamine Class ............................................................................67 5. Nicotinics .............................................................................................71 • Anabaseine Class ...........................................................................71 • Epibatidine Class ............................................................................71 • Mecamylamine Class .....................................................................72 • Miscellaneous .................................................................................72 • Nicotine Class .................................................................................74 6. Opioids .................................................................................................77 • Benzodiazole Class ........................................................................77 • Caged (photoactivatable) ..............................................................77 • Cyclohexyldiamine Class ...............................................................78 • Dihydromorphine Class ..................................................................78 ii NIDA Research Resources Drug Supply Program • Fentanyl Class ................................................................................78 • Hydrocodone Class ........................................................................83 • Meperidine Class ............................................................................83 • Metazocine Class ...........................................................................84 • Methadone Class ............................................................................87 • Miscellaneous .................................................................................96 • Morphinan Class .............................................................................97 • Morphine Class ...............................................................................97 • Orvinol Class .................................................................................101 • Oxymorphone Class .....................................................................102 • Phenylpiperidine Class .................................................................109 • Propoxyphene Class ....................................................................109 • Thebaine Class .............................................................................110 • Dosage Form: Implantable ...........................................................110 7. Peptides.............................................................................................111 • Caged (photoactivatable) ............................................................111 • Cannabinoid-related .....................................................................111 • Nicotinic Class ..............................................................................115 • Opioid Class..................................................................................116 • Orexin Class ..................................................................................138 8. Sedatives & Hypnotics......................................................................141 • Barbiturate Class ..........................................................................141 • Benzodiazepine Class ..................................................................143 • Butyrolactam Class ......................................................................143 • Methaqualone Class .....................................................................144 • Miscellaneous ...............................................................................146 9. Stimulants..........................................................................................147 • Aminorex Class .............................................................................147 NIDA Research Resources Drug Supply Program iii • Amphetamine Class......................................................................148 • Benzhydrol Class ..........................................................................150 • Cathinone Class............................................................................150 • Ephedrine Class ............................................................................152 • Methamphetamine Class .............................................................152 • Methylphenidate Class .................................................................155 • Miscellaneous ...............................................................................155 • Piperazine Class ...........................................................................155 • Tropane Class ...............................................................................156 • Dosage form: Stock Solutions .....................................................163 10. Miscellaneous Compounds..............................................................165 • Dopaminergic ................................................................................165 • Enzyme Inhibitors
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