AN ANALYSIS of the MINAMATA CONVENTION on MERCURY and ITS IMPLICATIONS for the REGULATION of MERCURY in SOUTH AFRICA by James Co
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Ethnic Differences in Risk from Mercury Among Savannah River Fishermen
Risk Analysis, Vol. 21, No. 3, 2001 Ethnic Differences in Risk from Mercury among Savannah River Fishermen Joanna Burger,1,2* Karen F. Gaines,3 and Michael Gochfeld2,4 Fishing plays an important role in people’s lives and contaminant levels in fish are a public health concern. Many states have issued consumption advisories; South Carolina and Geor- gia have issued them for the Savannah River based on mercury and radionuclide levels. This study examined ethnic differences in risk from mercury exposure among people consuming fish from the Savannah River, based on site-specific consumption patterns and analysis of mercury in fish. Among fish, there were significant interspecies differences in mercury levels, and there were ethnic differences in consumption patterns. Two methods of examining risk are presented: (1) Hazard Index (HI), and (2) estimates of how much and how often people of different body mass can consume different species of fish. Blacks consumed more fish and had higher HIs than Whites. Even at the median consumption, the HI for Blacks exceeded 1.0 for bass and bowfin, and, at the 75th percentile of consumption, the HI exceeded 1.0 for almost all species. At the White male median consumption, noHI exceeded 1, but for the 95th percentile consumer, the HI exceeded 1.0 almost regardless of which species were eaten. Although females consumed about two thirds the quantity of males, HIs exceeded 1 for most Black females and for White females at or above the 75th percentile of consump- tion. Thus, close to half of the Black fishermen were eating enough Savannah River fish to exceed HI 5 1. -
Food Safety Risk Assessment Related to Methylmercury in Seafood August 4
※ This report is translated by Food Safety Commission Secretariat, The Cabinet Office, Japan. Food Safety Risk Assessment Related to Methylmercury in Seafood August 4,2005 The Food Safety Commission, Japan The Contaminant Expert Committee Methylmercury in Seafood 1. Introduction To assure safety against methylmercury in seafood, the Ministry of Health, Labour and Welfare collected opinions of Joint Sub-Committees on Animal Origin Foods and Toxicology under the Food Sanitation Committee (Pharmaceutical Affairs and Food Sanitation Council(1))and published “Advice for Pregnant Women on Fish Consumption concerning Mercury Contamination” for pregnant and potentially pregnant women. Subsequently, after the application of the conventional assessment to a general population was reconfirmed, methylmercury was reassessed in the 61st Joint FAO/WHO Expert Committee on Food Additives (JECFA) in mid-June 2003 with a concern that fetuses and infants might have greater risks, based upon the results of epidemiological studies conducted in the Seychelles and Faroe Islands on effects of prenatal exposure to methylmercury via seafood on child neurodevelopment(the 61st JECFA (2), WHO (3)). To reassess the above Advice, the Ministry of Health, Labour and Welfare recently requested a food safety risk assessment of “methylmercury in seafood” to the Food Safety Committee in the document No. 07230001 from the Department of Food Safety, Pharmaceutical and Food Safety Bureau, Ministry of Health, Labour and Welfare under the date of July 23, 2004, in accordance with Article 24, Paragraph 3, Food Safety Basic Law (Law No. 48 2003). The concrete contents of the document requested for not only setting a tolerable intake of methylmercury to reassess the Advice for pregnant women and others concerning intake of methylmercury in seafood, but also discussing a high-risk group that might be subject to the Advice, since the high-risk group is not necessarily the same as those in foreign countries. -
Point Mutation Detection in the Cotton Rat. Christine H
Louisiana State University LSU Digital Commons LSU Historical Dissertations and Theses Graduate School 2000 Indices of Exposure to Polycyclic Aromatic Hydrocarbons in a Bioindicator Species: Point Mutation Detection in the Cotton Rat. Christine H. Lemarchand-carpentier Louisiana State University and Agricultural & Mechanical College Follow this and additional works at: https://digitalcommons.lsu.edu/gradschool_disstheses Recommended Citation Lemarchand-carpentier, Christine H., "Indices of Exposure to Polycyclic Aromatic Hydrocarbons in a Bioindicator Species: Point Mutation Detection in the Cotton Rat." (2000). LSU Historical Dissertations and Theses. 7277. https://digitalcommons.lsu.edu/gradschool_disstheses/7277 This Dissertation is brought to you for free and open access by the Graduate School at LSU Digital Commons. It has been accepted for inclusion in LSU Historical Dissertations and Theses by an authorized administrator of LSU Digital Commons. For more information, please contact [email protected]. INFORMATION TO USERS This manuscript has been reproduced from the microfilm master. UMI films the text directly from the original or copy submitted. Thus, some thesis and dissertation copies are in typewriter face, while others may be from any type of computer printer. The quality of this reproduction is dependent upon the quality of the copy submitted. Broken or indistinct print, colored or poor quality illustrations and photographs, print bleedthrough, substandard margins, and improper alignment can adversely affect reproduction. In the unlikely event that the author did not send UMI a complete manuscript and there are missing pages, these will be noted. Also, if unauthorized copyright material had to be removed, a note will indicate the deletion. Oversize materials (e.g., maps, drawings, charts) are reproduced by sectioning the original, beginning at the upper left-hand comer and continuing from left to right in equal sections with small overlaps. -
Lessons from an Early-Stage Epidemiological Study of Minamata Disease Takashi Yorifuji
Journal of Epidemiology Special Article J Epidemiol 2020;30(1):12-14 Lessons From an Early-stage Epidemiological Study of Minamata Disease Takashi Yorifuji Department of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan Received May 7, 2019; accepted September 17, 2019; released online November 2, 2019 Key words: environment and public health; epidemiology; food contamination; methylmercury compounds; Minamata disease Copyright © 2019 Takashi Yorifuji. This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Prefectures,5 but it is reported that several tens of thousands of INTRODUCTION residents have neurological signs related with methylmercury The Revisit series in this issue introduced the article by Kitamura poisoning in the exposed area.2,6 The causative factory, located in and colleagues.1 Dr. Shoji Kitamura, born in 1915, was a medical Minamata City, released effluent, which included methylmercury doctor and a professor of Department of Public Health in the as a byproduct of acetaldehyde production and contaminated local Medical School at Kumamoto University when Minamata disease seafood. The acetaldehyde production started in 1932, and it happened. The article summarized findings from a very-early- increased after the World War II, with a peak in 1960, and stopped phase epidemiological study conducted by researchers from in 1968. Along with the increase in production from around 1950, Kumamoto University immediately after the Minamata disease local residents witnessed strange phenomena.7 For example, large incident was officially recognized on May 1, 1956. -
D. Health and Environmental Sciences D1. Health Sciences (1
D. Health and Environmental Sciences D1. Health Sciences GIO: To acquire the basic knowledge, skills, and behavior about prevention of diseases and nutrition in contemporary society and to contribute to the people's health promotion and improvement of public health. (1) Public Health GIO: To acquire basic knowledge and skills on health statistics and epidemiology to learn current status and influential factors of public health. ① Definition of Health and Disease 1. To describe histories of the concepts of health and disease. ② Health Statistics 1. To describe the significance of population statistics in the current situation of public health. 2. To describe the technical terms in population and disease statistics. 3. To describe chronological changes in the demographic statistics (cause-specific mortality, etc.). ③ Epidemiology 1. To describe the role of epidemiology in disease prevention. 2. To describe the three major factors of epidemiology (agent, environment, host, etc.). 3. To describe the types of epidemiology (descriptive epidemiology, analytic epidemiology, etc.) and their methodologies. 4. To describe and calculate odds ratio, relative risk, attributable risk, and confidence interval for risk evaluation. (2) Disease Prevention GIO: To acquire the basic knowledge, skills, and behavior in the current situation and prevention of infectious disease, life-style related diseases, and occupational diseases, etc. ① Disease Prevention in Japan 1. To describe disease prevention in terms of three clinical stages such as health care, early diagnosis, and rehabilitation. 2. To describe Japanese health promotion policies (Health Japan 21, etc.). ② Infectious Diseases and Their Prevention 1. To describe contemporary infectious diseases (opportunistic infectious, hospital-acquired infectious, emerging infectious, and reemerging infectious diseases). -
Mercury in the Human Food Chain
Mercury in the Human Food Chain Food Toxicology Instructor: Gregory Möller, Ph.D. University of Idaho Learning Objectives • Explore the background and history of mercury. • Understand the environmental biogeochemistry of Hg. • Differentiate the toxicity profile of methylmercury. • Review the Minamata incident and it role in understanding the risk of mercury. • Review the results of the Seychelles and Faeroe Islands child development studies. • Understand the current regulatory findings and approach to managing mercury in the food chain. Mercury in History • HgS: Cinnabar, Vermillion • Native mercury • Ancient mining in Spain, Italy, China • Found in 1500 BC Egyptian tombs An Element of Mystery • Native mercury: argentum vivum • Mercury from condensing heated vapor of cinnabar: hydrargyrum (water silver, Gk) Turba Philosophorum • One of the earliest Latin alchemical texts, the Turba Philosophorum or assembly of the alchemical philosophers, dates from the 12th century. • "In the estimation of all Sages, Mercury is the first principle of all metals.” • "As flesh is generated from coagulated blood, so gold is generated out of coagulated Mercury.” Global Cycle of Mercury Aquatic Mercury Cycle 1 • In soil, mercury is relatively harmless in its elemental, divalent or particulate 2+ forms. It is only when Hg is converted to methylmercury (CH3Hg+) that it becomes a hazard. • Methylmercury is produced as a by- product of the metabolic processes of sulfate reducing bacteria in anaerobic environments. • It is not exactly known how inorganic mercury is converted to organic mercury during this process, but one hypothesis is that Hg2+ combines with S to form the salt HgS which is absorbed by the bacteria. HgS → CH3Hg(II)X + H Mercury in the Modern Environment • 70% of mercury in the environment comes from anthropogenic sources: metal mining and smelting, municipal & medical waste incineration, sewage, coal-fired power plants and cement manufacturing. -
Global Burden of Disease Attributable to Chemicals: Information Provided by the World Health Organization
SAICM/ICCM.3/INF/13 Distr.: General 20 June 2012 English only International Conference on Chemicals Management Third session Nairobi, 17–21 September 2012 Item 4 (d) of the provisional agenda* Implementation of the Strategic Approach to International Chemicals Management: Financial and technical resources for implementation Global burden of disease attributable to chemicals: information provided by the World Health Organization Note by the secretariat 1. The secretariat has the honour to circulate, in the annex to the present note, information provided by the World Health Organization (WHO) pursuant to resolution II/3 of the International Conference on Chemicals Management which encourages additional research on the economic and social costs of unsound chemicals management, including the cost of inaction and the implications for the health sector. 2. The annex contains the published WHO study "Known and unknowns on burden of disease due to chemicals: a systematic review"1. This study systematically reviews all available information on the global burden of disease involving chemicals through various media, including air, water, occupational exposures and direct ingestion. The study finds that globally, 4.9 million deaths (8.3% of total) and 86 million Disability- Adjusted Life Years (DALYs) (5.7% of total) were attributable to environmental exposure and management of selected chemicals in 2004 for which data were available. This figure includes indoor smoke from solid fuel use, outdoor air pollution and second-hand smoke, with 2.0, 1.2 and 0.6 million deaths annually. These are followed by occupational particulates, chemicals involved in acute poisonings, and pesticides involved in self- poisonings, with 375,000, 240,000 and 186,000 annual deaths respectively. -
Diseases Tiunsmitted by Foods
DISEASES TIUNSMITTED BY FOODS ( A CLASSIFICATION AND SUMMARY) SECOND EDITION U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES PUBLIC HEALTH SERVICE CENTERS FOR DISEASE CONTROL CENTER FOR PROFESSIONAL DEVELOPMENT AND TRAINING ATLANTA. GEORGIA 30333 DISEASES TIUNSMITTED BY FOODS ( A CIJiSSIFICATION AND SUMMARY) SECOND EDITION Frank L. Bryan, Ph.D., M.P.H. — U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES PUBLIC HEALTH SERVICE CENTERS FOR DISEASE CONTROL CENTER FOR PROFESSIONAL DEVE~PMENR AN_QTRAtNING ATLANTA, GEORGIA 30333 1982 DISEASES TRANSMITTED BY FOODS CONTENTS Page 1 INTRODUCTION 2 BACTERIAL DISEASES 2 Diseases of Contemporary Importance 7 Usually Transmitted by Other Means but Sometimes Foodborne Diseases in Which Proof of Transmission by Foods Is Inconclusive Unknown Role in Foodborne Transmission (Pathogenic and 16 Isolated from Foods) 17 VIRAL AND RICKETTSIW DISEASES 17 Epidemiological Evidence of Foodborne Transmission Viral Diseases which Could Possible be Transmitted by Foods but Proof Is Lacking 18 -I.-I PAMSITIC DISEASES LL 22 Always or Usually Transmitted by Foods 29 Usually Transmitted by Other Means but Sometimes Foodborne 33 FUNGAL DISEASES ‘- 33 Mycotoxicoses 37 Mushrooms 42 Mycotic Infections 43 PLANT TOXICANTS AND TOXINS 43 Alkaloids 47 Glycosides 4.9 Toxalbumins Resins 50 50 Other Toxicants, Toxins, and Allergens 54 TOXIC ANIM4LS 54 Fish Shellfish 53 60 Other Marine Animals 62 Non-Marine Animals 64 POISONOUS CHEMICALS 64 Metallic’Containers 65 Intentional Additives 68 Incidental and Accidental Food Additives 75 Allergens -
Food Safety with Special Reference to Public Health - G.A
INTERACTIONS: FOOD, AGRICULTURE AND ENVIRONMENT – Vol. I - Food Safety With Special Reference to Public Health - G.A. Talanov FOOD SAFETY WITH SPECIAL REFERENCE TO PUBLIC HEALTH G.A. Talanov All-Russian Research Institute for Veterinary Sanitation, Hygiene and Ecology, Russian Academy of Agricultural Sciences, Russia Keywords: Food products, food safety, food-borne diseases, pesticides, mycotoxins, radionuclides, helminthes, heavy metals Contents 1. Introduction 2. Occurrence of the food-borne diseases 3. Control of the food safety 4. Conclusion Glossary Bibliography Biographical Sketch Summary In parallel with such important things as an air for breathing and water for drinking, food is one of the most important factors in the life support systems. It is known that a human- being can not survive a few minutes without breathing the air, several days without drinking the water, and slightly longer, however not very long, i.e. 25-30 days without a food. At the same time, the food products can be infected with pathogenic microorganisms, or contain toxic chemicals and radionuclides. The most dangerous are the agents of zoonoses, i.e. diseases, which are common for humans and animals (anthrax, tubercullosis, brucellosis) as well as toxic microorganisms, such as Salmonella, Clostridium, Streptococcus and Staphyloccocus causing the food- borne diseases. Through meat and meat products humans can be infected by trichinelliasis, taeniidosis, onchocerciasis, and diphyllobothriasis. Food products can be contaminated by heavy metals (mercury, cadmium, lead), dioxins, polychlorinated biphenyls, mycotoxins, phytotoxins,UNESCO radionuclides in quantities exceedin– EOLSSg admissible levels. To provide safety of the food products a complex of measures has been developed to prevent any contaminationSAMPLE of them with dangerous CHAPTERS biological, chemical and radioactive contaminants, and ways and methods for utilization of contaminated products have been proposed. -
Characterization of Human Health and Wildlife Risks from Mercury Exposure in the United States
United States EPA-452/R-97-009 Environmental Protection December 1997 Agency Air Mercury Study Report to Congress Volume VII: Characterization of Human Health and Wildlife Risks from Mercury Exposure in the United States Office of Air Quality Planning & Standards and Office of Research and Development c7o032-1-1 MERCURY STUDY REPORT TO CONGRESS VOLUME VII: CHARACTERIZATION OF HUMAN HEALTH AND WILDLIFE RISKS FROM MERCURY EXPOSURE IN THE UNITED STATES December 1997 Office of Air Quality Planning and Standards and Office of Research and Development U.S. Environmental Protection Agency TABLE OF CONTENTS Page U.S. EPA AUTHORS ................................................................iii SCIENTIFIC PEER REVIEWERS ......................................................iv WORK GROUP AND U.S. EPA/ORD REVIEWERS ...................................... vii LIST OF TABLES .................................................................. viii LIST OF FIGURES ..................................................................ix LIST OF SYMBOLS, UNITS AND ACRONYMS ......................................... x 1. INTRODUCTION ...........................................................1-1 2. HUMAN HEALTH EFFECTS: HAZARD IDENTIFICATION AND DOSE- RESPONSE ................................................................2-1 2.1 Health Hazards Associated with Mercury Exposure ...........................2-1 2.2 Dose-Response to Methylmercury ........................................2-3 2.2.1 Calculation of Methylmercury RfD .................................2-3 -
Pahs: Comparative Biotransformation and Trophic Transfer of Their Metabolites in the Aquatic Environment
dissertations Victor Carrasco Navarro PAHs: Comparative bio- | Victor 106 | No Carrasco Navarro | transformation and trophic transfer of their metabolites in the aquatic environment Polycyclic aromatic hydrocarbons (PAH) are a group of widespread contaminants in the aquatic environ- Victor Carrasco Navarro ment. They may biotransform once they enter an animal’s tissue and the products of biotransformation PAHs: Comparative may be more toxic than the parent biotransformation and trophic compounds. In the present thesis, a ComparativePAHs: biotransformation and trophic transfer their metabolites... of comparison of the biotransformation transfer of their metabolites of a model PAH among several taxa of invertebrates and fish is presented. in the aquatic environment The trophic transfer of some of the Fate of Polycyclic Aromatic Hydrocarbons metabolites produced by black worms and nonbiting mosquito larvae to fish in aquatic experiments and shrimp is also covered and dem- onstrated. Publications of the University of Eastern Finland Publications of the University of Eastern Finland Dissertations in Forestry and Natural Sciences No 106 Dissertations in Forestry and Natural Sciences isbn: 978-952-61-1137-7 (nid.) issnl: 1798-5668 issn: 1798-5668 isbn: 978-952-61-1138-4 (pdf) issn: 1798-5676 (pdf) VICTOR CARRASCO NAVARRO PAHs: Comparative biotransformation and trophic transfer of their metabolites in the aquatic environment Fate of Polycyclic Aromatic Hydrocarbons in aquatic experiments Publications of the University of Eastern Finland Dissertations in Forestry and Natural Sciences No 106 Academic Dissertation To be presented by permission of the Faculty of Science and Forestry for public examination in the Auditorium N100 in Natura Building at the University of Eastern Finland, Joensuu, on June, 14, 2013, at 12 o’clock noon. -
Hisashi Yokoyama
SPRINGER BRIEFS IN ENVIRONMENTAL SCIENCE Hisashi Yokoyama Mercury Pollution in Minamata SpringerBriefs in Environmental Science SpringerBriefs in Environmental Science present concise summaries of cutting- edge research and practical applications across a wide spectrum of environmental fields, with fast turnaround time to publication. Featuring compact volumes of 50 to 125 pages, the series covers a range of content from professional to academic. Monographs of new material are considered for the SpringerBriefs in Environmental Science series. Typical topics might include: a timely report of state-of-the-art analytical techniques, a bridge between new research results, as published in journal articles and a contextual literature review, a snapshot of a hot or emerging topic, an in-depth case study or technical example, a presentation of core concepts that students must understand in order to make independent contributions, best practices or protocols to be followed, a series of short case studies/debates highlighting a specific angle. SpringerBriefs in Environmental Science allow authors to present their ideas and readers to absorb them with minimal time investment. Both solicited and unsolicited manuscripts are considered for publication. More information about this series at http://www.springernature.com/series/8868 Hisashi Yokoyama Mercury Pollution in Minamata Hisashi Yokoyama Educational Unit for Studies of Hills, Humans and Oceans Kyoto University Kyoto, Japan ISSN 2191-5547 ISSN 2191-5555 (electronic) SpringerBriefs in Environmental Science ISBN 978-981-10-7391-5 ISBN 978-981-10-7392-2 (eBook) https://doi.org/10.1007/978-981-10-7392-2 Library of Congress Control Number: 2017960830 © The Author(s) 2018. This book is an open access publication.