June 16, 2015 u vol. 112 u no. 24 u 7333–7616

Cover image: Pictured is a person carrying a basket up the steep slopes of the Longji rice terraces in Guangxi province, China. The as Capital PNAS 100th Anniversary Special Feature, appearing in this issue, suggests that despite high awareness of the interdependence between ecosystems, economic systems, and human health and numerous examples of trans- lation of conceptual understanding into management practices, adoption of these ideas by corporations and governments is not yet widespread. See the Introduction to the Special Feature by Anne D. Guerry et al. on pages 7348–7355. Image courtesy of Stacie Wolny (Natural Capital Project). From the Cover

7348 Nature as capital 7426 Identifying scientific Sleeping Beauties 7472 Tropical tree species richness 7530 Ruggedness of fitness landscapes

Contents SCIENCE AND CULTURE—How science intersects with culture 7335 Science and Culture: Oppenheimer goes center stage Amber Dance THIS WEEK IN PNAS

7333 In This Issue CORE CONCEPTS—A brief introduction to emerging topics in science

7337 Core Concept: Ecosystem services Amy West LETTERS (ONLINE ONLY)

E3090 Questioning the biogenicity of titanite mineral trace fossils in Archean QNAS pillow lavas Eugene G. Grosch and Nicola McLoughlin 7339 QnAs with Jane Lubchenco E3092 Reply to Grosch and McLoughlin: Glass bioalteration Paul Gabrielsen trace fossils can be preserved by titanite in 7341 QnAs with Paleoarchean greenstones Prashant Nair Hubert Staudigel, Harald Furnes, and Maarten DeWit E3093 Optimal foraging theory and niche-construction theory do not stand in opposition Kathryn A. Mohlenhoff, Joan Brenner Coltrain, COMMENTARIES and Brian F. Codding E3094 Reply to Mohlenhoff et al.: Human behavioral 7343 Estimating the global number of tropical tree species, needs a rethink that niche-construction theory and Fisher’s paradox can provide Stephen P. Hubbell Melinda A. Zeder See companion article on page 7472 7345 Measuring ruggedness in fitness landscapes Jeremy Van Cleve and Daniel B. Weissman Free online through the PNAS open access option. See companion article on page 7530

PNAS u June 16, 2015 u vol. 112 u no. 24 u iii–vii Downloaded by guest on September 28, 2021 7402 Spatial patterns of agricultural expansion determine PNAS PLUS impacts on and carbon storage Rebecca Chaplin-Kramer, Richard P. Sharp, Lisa Mandle, 7347 Significance Statements Sarah Sim, Justin Johnson, Isabela Butnar, Llorenç Brief statements written by the authors about the significance Milà i Canals, Bradley A. Eichelberger, Ivan Ramler, Carina of their papers. Mueller, Nikolaus McLachlan, Anahita Yousefi, Henry King, and Peter M. Kareiva 7408 Conserving tropical biodiversity via market forces and spatial targeting Ian J. Bateman, Emma Coombes, Emily Fitzherbert, Amy NATURE AS CAPITAL PNAS 100th ANNIVERSARY Binner, Tomás Bad’ura, Chris Carbone, Brendan Fisher, SPECIAL FEATURE Robin Naidoo, and Andrew R. Watkinson 7414 Public health impacts of ecosystem change in the INTRODUCTION Brazilian Amazon 7348 Natural capital and ecosystem services informing Simone C. Bauch, Anna M. Birkenbach, Subhrendu K. decisions: From promise to practice Pattanayak, and Erin O. Sills Anne D. Guerry, Stephen Polasky, Jane Lubchenco, Rebecca 7420 Estimating the impacts of conservation on ecosystem Chaplin-Kramer, Gretchen C. Daily, Robert Griffin, Mary Ruckelshaus, Ian J. Bateman, Anantha Duraiappah, Thomas services and poverty by integrating modeling and evaluation Elmqvist, Marcus W. Feldman, Carl Folke, Jon Hoekstra, Peter M. Kareiva, Bonnie L. Keeler, Shuzhuo Li, Emily Paul J. Ferraro, Merlin M. Hanauer, Daniela A. Miteva, McKenzie, Zhiyun Ouyang, Belinda Reyers, Taylor H. Joanna L. Nelson, Subhrendu K. Pattanayak, Christoph Nolte, Ricketts, Johan Rockström, Heather Tallis, and Katharine R. E. Sims and Bhaskar Vira

PERSPECTIVES PHYSICAL SCIENCES 7356 Setting the bar: Standards for ecosystem services Stephen Polasky, Heather Tallis, and Belinda Reyers APPLIED PHYSICAL SCIENCES 7426 Defining and identifying Sleeping Beauties in science 7362 Navigating complexity through knowledge Qing Ke, Emilio Ferrara, Filippo Radicchi, coproduction: Mainstreaming ecosystem and Alessandro Flammini services into disaster risk reduction Belinda Reyers, Jeanne L. Nel, Patrick J. O’Farrell, 7563 Type IV pili mechanochemically regulate virulence Nadia Sitas, and Deon C. Nel factors in Pseudomonas aeruginosa Alexandre Persat, Yuki F. Inclan, Joanne N. Engel, 7375 Improving global environmental management with Howard A. Stone, and Zemer Gitai standard corporate reporting Peter M. Kareiva, Brynn W. McNally, Steve McCormick, Tom Miller, and Mary Ruckelshaus CHEMISTRY 7383 Nature as capital: Advancing and incorporating 7432 Long-range electrostatic screening in ionic liquids ecosystem services in United States federal Matthew A. Gebbie, Howard A. Dobbs, Markus Valtiner, policies and programs and Jacob N. Israelachvili Mark Schaefer, Erica Goldman, Ann M. Bartuska, 7438 Quantum tunneling observed without its characteristic Ariana Sutton-Grier, and Jane Lubchenco large kinetic isotope effects Tetsuya Hama, Hirokazu Ueta, Akira Kouchi, and Naoki Watanabe RESEARCH ARTICLES 7369 Adaptive governance, ecosystem management, and 7484 Temperature dependence of amino natural capital acid hydrophobicities Lisen Schultz, Carl Folke, Henrik Österblom, Richard Wolfenden, Charles A. Lewis Jr., Yang Yuan, and Per Olsson and Charles W. Carter Jr. 7390 Embedding ecosystem services in coastal planning leads 7489 tRNA acceptor stem and anticodon bases to better outcomes for people and nature form independent codes related to Katie K. Arkema, Gregory M. Verutes, Spencer A. Wood, protein folding Chantalle Clarke-Samuels, Samir Rosado, Maritza Canto, Charles W. Carter Jr. and Richard Wolfenden Amy Rosenthal, Mary Ruckelshaus, Gregory Guannel, Jodie Toft, Joe Faries, Jessica M. Silver, Robert Griffin, PHYSICS and Anne D. Guerry 7444 Imaging transient melting of a nanocrystal using an 7396 Impacts of conservation and human development policy X-ray laser across stakeholders and scales Jesse N. Clark, Loren Beitra, Gang Xiong, David M. Fritz, Cong Li, Hua Zheng, Shuzhuo Li, Xiaoshu Chen, Jie Li, Henrik T. Lemke, Diling Zhu, Matthieu Chollet, Garth J. Weihong Zeng, Yicheng Liang, Stephen Polasky, Marcus W. Williams, Marc M. Messerschmidt, Brian Abbey, Ross J. Feldman, Mary Ruckelshaus, Zhiyun Ouyang, Harder, Alexander M. Korsunsky, Justin S. Wark, and Gretchen C. Daily David A. Reis, and Ian K. Robinson

iv u www.pnas.org Downloaded by guest on September 28, 2021 7449 Algorithmic lattice kirigami: A route to APPLIED BIOLOGICAL SCIENCES pluripotent materials 7472 An estimate of the number of tropical Daniel M. Sussman, Yigil Cho, Toen Castle, Xingting Gong, tree species Euiyeon Jung, Shu Yang, and Randall D. Kamien J. W. Ferry Slik, Víctor Arroyo-Rodríguez, Shin-Ichiro Aiba, Patricia Alvarez-Loayza, Luciana F. Alves, STATISTICS Peter Ashton, Patricia Balvanera, Meredith L. 7454 Identifying localized changes in large systems: Change- Bastian, Peter J. Bellingham, Eduardo van den Berg, point detection for biomolecular simulations Luis Bernacci, Polyanna da Conceição Bispo, Zhou Fan, Ron O. Dror, Thomas J. Mildorf, Stefano Piana, Lilian Blanc, Katrin Böhning-Gaese, Pascal Boeckx, and David E. Shaw Frans Bongers, Brad Boyle, Matt Bradford, Francis Q. Brearley, Mireille Breuer-Ndoundou Hockemba, Sarayudh Bunyavejchewin, Darley Calderado Leal Matos, SOCIAL SCIENCES Miguel Castillo-, Eduardo L. M. Catharino, Shauna-Lee Chai, Yukai Chen, Robert K. Colwell, PSYCHOLOGICAL AND COGNITIVE SCIENCES Chazdon L. Robin, Connie Clark, David B. Clark, Deborah A. Clark, Heike Culmsee, Kipiro Damas, E3123 Oxytocin modulates fMRI responses to facial expression Handanakere S. Dattaraja, Gilles Dauby, Priya Davidar, in macaques Saara J. DeWalt, Jean-Louis Doucet, Alvaro Duque, Ning Liu, Fadila Hadj-Bouziane, Katherine B. Jones, Janita N. Giselda Durigan, Karl A. O. Eichhorn, Pedro V. Turchi, Bruno B. Averbeck, and Leslie G. Ungerleider Eisenlohr, Eduardo Eler, Corneille Ewango, Nina 7460 Group discussion improves lie detection Farwig, Kenneth J. Feeley, Leandro Ferreira, Richard Nadav Klein and Nicholas Epley Field, Ary T. de Oliveira Filho, Christine Fletcher, Olle Forshed, Geraldo Franco, Gabriella Fredriksson, SOCIAL SCIENCES Thomas Gillespie, Jean-François Gillet, Giriraj Amarnath, Daniel M. Griffith, James Grogan, Nimal 7426 Defining and identifying Sleeping Beauties in science Gunatilleke, David Harris, Rhett Harrison, Andy Hector, Qing Ke, Emilio Ferrara, Filippo Radicchi, Jürgen Homeier, Nobuo Imai, Akira Itoh, Patrick A. and Alessandro Flammini Jansen, Carlos A. Joly, Bernardus H. J. de Jong, Kuswata Kartawinata, Elizabeth Kearsley, Daniel L. SUSTAINABILITY SCIENCE Kelly, David Kenfack, Michael Kessler, Kanehiro 7369 Adaptive governance, ecosystem management, and Kitayama, Robert Kooyman, Eileen Larney, Yves natural capital Laumonier, Susan Laurance, William F. Laurance, Lisen Schultz, Carl Folke, Henrik Österblom, Michael J. Lawes, Ieda Leao do Amaral, Susan G. and Per Olsson Letcher, Jeremy Lindsell, Xinghui Lu, Asyraf Mansor, 7390 Embedding ecosystem services in coastal planning leads Antti Marjokorpi, Emanuel H. Martin, Henrik Meilby, to better outcomes for people and nature Felipe P. L. Melo, Daniel J. Metcalfe, Vincent P. Katie K. Arkema, Gregory M. Verutes, Spencer A. Wood, Medjibe, Jean Paul Metzger, Jerome Millet, Chantalle Clarke-Samuels, Samir Rosado, Maritza Canto, D. Mohandass, Juan C. Montero, Márcio de Morisson Amy Rosenthal, Mary Ruckelshaus, Gregory Guannel, Valeriano, Badru Mugerwa, Hidetoshi Nagamasu, Jodie Toft, Joe Faries, Jessica M. Silver, Robert Griffin, Reuben Nilus, Susana Ochoa-Gaona, Onrizal, Navendu and Anne D. Guerry Page, Pia Parolin, Marc Parren, Narayanaswamy Parthasarathy, Ekananda Paudel, Andrea Permana, 7408 Conserving tropical biodiversity via market forces and Maria T. F. Piedade, Nigel C. A. Pitman, Lourens spatial targeting Poorter, Axel D. Poulsen, John Poulsen, Jennifer Ian J. Bateman, Emma Coombes, Emily Fitzherbert, Amy Powers, Rama C. Prasad, Jean-Philippe Puyravaud,  ’ Binner, Tomás Bad ura, Chris Carbone, Brendan Fisher, Jean-Claude Razafimahaimodison, Jan Reitsma, João Robin Naidoo, and Andrew R. Watkinson Roberto dos Santos, Wilson Roberto Spironello, Hugo 7414 Public health impacts of ecosystem change in the Romero-Saltos, Francesco Rovero, Andes Hamuraby Brazilian Amazon Rozak, Kalle Ruokolainen, Ervan Rutishauser, Felipe Simone C. Bauch, Anna M. Birkenbach, Subhrendu K. Saiter, Philippe Saner, Braulio A. Santos, Fernanda Pattanayak, and Erin O. Sills Santos, Swapan K. Sarker, Manichanh Satdichanh, Christine B. Schmitt, Jochen Schöngart, Mark Schulze, 7420 Estimating the impacts of conservation on ecosystem Marcio S. Suganuma, Douglas Sheil, Eduardo da Silva services and poverty by integrating modeling Pinheiro, Plinio Sist, Tariq Stevart, Raman Sukumar, and evaluation I.-Fang Sun, Terry Sunderand, H. S. Suresh, Eizi Suzuki, Paul J. Ferraro, Merlin M. Hanauer, Daniela A. Miteva, Marcelo Tabarelli, Jangwei Tang, Natália Targhetta, Ida Joanna L. Nelson, Subhrendu K. Pattanayak, Christoph Nolte, Theilade, Duncan W. Thomas, Peguy Tchouto, Johanna and Katharine R. E. Sims Hurtado, Renato Valencia, Johan L. C. H. van Valkenburg, Tran Van Do, Rodolfo Vasquez, Hans Verbeeck, BIOLOGICAL SCIENCES Victor Adekunle, Simone A. Vieira, Campbell O. Webb, Timothy Whitfeld, Serge A. Wich, John Williams, Florian Wittmann, Hannsjoerg Wöll, Xiaobo Yang, ANTHROPOLOGY C. Yves Adou Yao, Sandra L. Yap, Tsuyoshi Yoneda, 7466 Body composition in Pan paniscus compared with Homo Rakan A. Zahawi, Rahmad Zakaria, Runguo Zang, sapiens has implications for changes during Rafael L. de Assis, Bruno Garcia Luize, human evolution and Eduardo M. Venticinque Adrienne L. Zihlman and Debra R. Bolter See Commentary on page 7343

PNAS u June 16, 2015 u vol. 112 u no. 24 u v Downloaded by guest on September 28, 2021 BIOCHEMISTRY EVOLUTION 7478 Destructin-1 is a collagen-degrading endopeptidase 7524 Gain of cis-regulatory activities underlies novel secreted by Pseudogymnoascus destructans, the domains of wingless gene expression causative agent of white-nose syndrome in Drosophila Anthony J. O’Donoghue, Giselle M. Knudsen, Chapman Shigeyuki Koshikawa, Matt W. Giorgianni, Kathy Vaccaro, Beekman, Jenna A. Perry, Alexander D. Johnson, Victoria A. Kassner, John H. Yoder, Thomas Werner, Joseph L. DeRisi, Charles S. Craik, and Sean B. Carroll and Richard J. Bennett 7530 A tortoise–hare pattern seen in adapting structured and unstructured populations suggests a rugged fitness BIOPHYSICS AND COMPUTATIONAL landscape in bacteria Joshua R. Nahum, Peter Godfrey-Smith, Brittany N. Harding, E3095 Accurate secondary structure prediction Joseph H. Marcus, Jared Carlson-Stevermer, and fold recognition for circular and Benjamin Kerr dichroism spectroscopy See Commentary on page 7345 András Micsonai, Frank Wien, Linda Kernya, Young-Ho Lee, Yuji Goto, Matthieu Réfrégiers, 7536 Evolutionary and phenotypic analysis of live virus and József Kardos isolates suggests arthropod origin of a pathogenic RNA virus family 7454 Identifying localized changes in large systems: Change- Marco Marklewitz, Florian Zirkel, Andreas Kurth, point detection for biomolecular simulations Christian Drosten, and Sandra Junglen Zhou Fan, Ron O. Dror, Thomas J. Mildorf, Stefano Piana, and David E. Shaw 7542 Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological 7484 Temperature dependence of amino associating domains borders acid hydrophobicities Carlos Gómez-Marín, Juan J. Tena, Rafael D. Acemel, Richard Wolfenden, Charles A. Lewis Jr., Yang Yuan, Macarena López-Mayorga, Silvia Naranjo, Elisa and Charles W. Carter Jr. de la Calle-Mustienes, Ignacio Maeso, Leonardo Beccari, 7489 tRNA acceptor stem and anticodon bases Ivy Aneas, Erika Vielmas, Paola Bovolenta, Marcelo A. form independent codes related to Nobrega, Jaime Carvajal, and José Luis Gómez-Skarmeta protein folding Charles W. Carter Jr. and Richard Wolfenden GENETICS 7495 Direct observation of DNA overwinding by E3114 Extrachromosomal circular DNA is common reverse gyrase in yeast Taisaku Ogawa, Katsunori Yogo, Shou Furuike, Kazuo Sutoh, Henrik D. Møller, Lance Parsons, Tue S. Jørgensen, Akihiko Kikuchi, and Kazuhiko Kinosita Jr. David Botstein, and Birgitte Regenberg 7501 Tau stabilizes microtubules by binding at the interface 7548 Porcupine inhibitor suppresses paracrine Wnt-driven between tubulin heterodimers growth of Rnf43;Znrf3-mutant neoplasia Harindranath Kadavath, Romina V. Hofele, Jacek Bon-Kyoung Koo, Johan H. van Es, Maaike van den Born, Biernat, Satish Kumar, Katharina Tepper, and Hans Clevers Henning Urlaub, Eckhard Mandelkow, and Markus Zweckstetter IMMUNOLOGY AND INFLAMMATION 7551 Focusing and sustaining the antitumor CTL effector killer CELL BIOLOGY response by agonist anti-CD137 mAb E3104 Ionic imbalance, in addition to molecular crowding, Bettina Weigelin, Elixabet Bolaños, Alvaro Teijeira, Ivan abates cytoskeletal dynamics and vesicle motility Martinez-Forero, Sara Labiano, Arantza Azpilikueta, Aizea during hypertonic stress Morales-Kastresana, José I. Quetglas, Esther Wagena, Paula Nunes, Isabelle Roth, Paolo Meda, Eric Féraille, Alfonso Rodríguez Sánchez-Paulete, Lieping Chen, Dennis Brown, and Udo Hasler Peter Friedl, and Ignacio Melero 7507 Histone chaperone Anp32e removes H2A.Z from DNA 7557 IL-1R signaling enables bystander cells to overcome double-strand breaks and promotes nucleosome bacterial blockade of host protein synthesis reorganization and DNA repair Alan M. Copenhaver, Cierra N. Casson, Hieu T. Nguyen, Ozge Gursoy-Yuzugullu, Marina K. Ayrapetov, Matthew M. Duda, and Sunny Shin and Brendan D. Price

MICROBIOLOGY ECOLOGY 7563 Type IV pili mechanochemically regulate virulence 7513 Microbial invasion of the Caribbean by an Indo-Pacific factors in Pseudomonas aeruginosa coral zooxanthella Alexandre Persat, Yuki F. Inclan, Joanne N. Engel, D. Tye Pettay, Drew C. Wham, Robin T. Smith, Roberto Howard A. Stone, and Zemer Gitai Iglesias-Prieto, and Todd C. LaJeunesse 7569 Precision-guided antimicrobial peptide as a targeted 7519 New approaches narrow global species estimates for modulator of human microbial ecology beetles, insects, and terrestrial arthropods Lihong Guo, Jeffrey S. McLean, Youngik Yang, Randal Nigel E. Stork, James McBroom, Claire Gely, Eckert, Christopher W. Kaplan, Pierre Kyme, Omid Sheikh, and Andrew J. Hamilton Brian Varnum, Renate Lux, Wenyuan Shi, and Xuesong He

vi u www.pnas.org Downloaded by guest on September 28, 2021 7575 A tyrosine-based motif in the HIV-1 envelope 7390 Embedding ecosystem services in coastal planning leads glycoprotein tail mediates cell-type– and to better outcomes for people and nature Rab11-FIP1C–dependent incorporation Katie K. Arkema, Gregory M. Verutes, Spencer A. Wood, into virions Chantalle Clarke-Samuels, Samir Rosado, Maritza Canto, Mingli Qi, Hin Chu, Xuemin Chen, Junghwa Choi, Xiaoyun Amy Rosenthal, Mary Ruckelshaus, Gregory Guannel, Wen, Jason Hammonds, Lingmei Ding, Eric Hunter, Jodie Toft, Joe Faries, Jessica M. Silver, Robert Griffin, and Paul Spearman and Anne D. Guerry 7581 Two-level inhibition of galK expression by Spot 42: 7396 Impacts of conservation and human development policy Degradation of mRNA mK2 and enhanced transcription across stakeholders and scales termination before the galK gene Cong Li, Hua Zheng, Shuzhuo Li, Xiaoshu Chen, Jie Li, Xun Wang, Sang Chun Ji, Heung Jin Jeon, Yonho Lee, Weihong Zeng, Yicheng Liang, Stephen Polasky, Marcus W. and Heon M. Lim Feldman, Mary Ruckelshaus, Zhiyun Ouyang, and Gretchen C. Daily NEUROSCIENCE 7402 Spatial patterns of agricultural expansion determine E3123 Oxytocin modulates fMRI responses to facial expression impacts on biodiversity and carbon storage in macaques Rebecca Chaplin-Kramer, Richard P. Sharp, Lisa Mandle, Ning Liu, Fadila Hadj-Bouziane, Katherine B. Jones, Janita N. Sarah Sim, Justin Johnson, Isabela Butnar, Llorenç Turchi, Bruno B. Averbeck, and Leslie G. Ungerleider Milà i Canals, Bradley A. Eichelberger, Ivan Ramler, Carina Mueller, Nikolaus McLachlan, Anahita Yousefi, Henry King, E3131 Progressive maturation of silent synapses governs the and Peter M. Kareiva duration of a critical period Xiaojie Huang, Sophia K. Stodieck, Bianka Goetze, Lei Cui, 7420 Estimating the impacts of conservation on ecosystem Man Ho Wong, Colin Wenzel, Leon Hosang, Yan Dong, services and poverty by integrating modeling Siegrid Löwel, and Oliver M. Schlüter and evaluation Paul J. Ferraro, Merlin M. Hanauer, Daniela A. Miteva, E3141 Rab3-interacting molecules 2α and 2β promote the + Joanna L. Nelson, Subhrendu K. Pattanayak, Christoph Nolte, abundance of voltage-gated Ca 1.3 Ca2 channels V and Katharine R. E. Sims at hair cell active zones Sangyong Jung, Tomoko Oshima-Takago, Rituparna 7611 Financial competitiveness of organic agriculture on Chakrabarti, Aaron B. Wong (黃沛燊), Zhizi Jing, Gulnara a global scale Yamanbaeva, Maria Magdalena Picher, Sonja M. Wojcik, David W. Crowder and John P. Reganold Fabian Göttfert, Friederike Predoehl, Katrin Michel, Stefan W. Hell, Susanne Schoch, Nicola Strenzke, Carolin Wichmann, and Tobias Moser CORRECTIONS (ONLINE ONLY) 7587 Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum NEWS FEATURE ’ Delphine Meffre, Ghjuvan Ghjacumu Shackleford, Mehdi E3150 News Feature: Microplastics present pollution puzzle Hichor, Victor Gorgievski, Eleni T. Tzavara, Amalia Alla Katsnelson Trousson, Abdel M. Ghoumari, Cyrille Deboux, Brahim Nait Oumesmar, Philippe Liere, Michael Schumacher, Etienne-Emile Baulieu, Frédéric Charbonnier, Julien APPLIED BIOLOGICAL SCIENCES Grenier, and Charbel Massaad E3151 Design and formulation of functional pluripotent stem cell-derived cardiac microtissues 7593 Amphetamine modulates brain signal variability and Nimalan Thavandiran, Nicole Dubois, Alexander Mikryukov, working memory in younger and older adults Stéphane Massé, Bogdan Beca, Craig A. Simmons, Vikram S. Douglas D. Garrett, Irene E. Nagel, Claudia Preuschhof, Deshpande, J. Patrick McGarry, Christopher S. Chen, Agnieszka Z. Burzynska, Janina Marchner, Steffen Wiegert, Kumaraswamy Nanthakumar, Gordon M. Keller, Milica Gerhard J. Jungehülsing, Lars Nyberg, Arno Villringer, Radisic, and Peter W. Zandstra Shu-Chen Li, Hauke R. Heekeren, Lars Bäckman, and Ulman Lindenberger BIOCHEMISTRY 7599 Transgenic songbirds with suppressed or enhanced E3152 Destructin-1 is a collagen-degrading endopeptidase activity of CREB transcription factor secreted by Pseudogymnoascus destructans, the Kentaro Abe, Sumiko Matsui, and Dai Watanabe causative agent of white-nose syndrome Anthony J. O’Donoghue, Giselle M. Knudsen, Chapman PLANT BIOLOGY Beekman, Jenna A. Perry, Alexander D. Johnson, Joseph L. 7605 Asymptomatic spread of huanglongbing and DeRisi, Charles S. Craik, and Richard J. Bennett implications for disease control Jo Ann Lee, Susan E. Halbert, William O. Dawson, Cecile J. EVOLUTION Robertson, James E. Keesling, and Burton H. Singer E3153 Biological evidence supports an early and complex emergence of the Isthmus of Panama SUSTAINABILITY SCIENCE Christine D. Bacon, Daniele Silvestro, Carlos Jaramillo, Brian Tilston Smith, Prosanta Chakrabarty, 7369 Adaptive governance, ecosystem management, and and Alexandre Antonelli natural capital Lisen Schultz, Carl Folke, Henrik Österblom, and Per Olsson ix Subscription Form

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