The Neuroeconomics of Nicotine Dependence: a Preliminary Functional Magnetic Resonance Imaging Study of Delay Discounting of Monetary and Cigarette Rewards in Smokers
PSYN-09876; No of Pages 10 Psychiatry Research: Neuroimaging xxx (2012) xxx–xxx Contents lists available at SciVerse ScienceDirect Psychiatry Research: Neuroimaging journal homepage: www.elsevier.com/locate/psychresns The neuroeconomics of nicotine dependence: A preliminary functional magnetic resonance imaging study of delay discounting of monetary and cigarette rewards in smokers James MacKillop a,b,⁎, Michael T. Amlung a, Lauren M. Wier c, Sean P. David d,e, Lara A. Ray f, Warren K. Bickel g, Lawrence H. Sweet h a Department of Psychology, University of Georgia, Athens, GA, United States b Center for Alcohol and Addiction Studies, Brown University, Providence, RI, United States c Boston University School of Public Health, Boston, MA, United States d Department of Community Medicine, Stanford University School of Medicine, Palo Alto, CA, United States e SRI International, Menlo Park, CA, United States f Department of Psychology, University of California, Los Angeles, CA, United States g Center for Substance Abuse Research, Virginia Tech Carilion Research Institute, Roanoke, VA, United States h Translational Research Group, Department of Psychiatry and Human Behavior, Brown University, Providence, RI, United States article info abstract Article history: Neuroeconomics integrates behavioral economics and cognitive neuroscience to understand the neurobio- Received 18 March 2011 logical basis for normative and maladaptive decision making. Delay discounting is a behavioral economic Received in revised form 22 August 2011 index of impulsivity that reflects capacity to delay gratification and has been consistently associated with Accepted 7 October 2011 nicotine dependence. This preliminary study used functional magnetic resonance imaging to examine Available online xxxx delay discounting for money and cigarette rewards in 13 nicotine dependent adults.
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