Compendial Approvals for USP36-NF31, Second Supplement
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“Polyols: a Primer for Dietetic Professionals” Is a Self-Study
1 “Polyols: A primer for dietetic professionals” is a self-study module produced by the Calorie Control Council, an accredited provider of continuing professional education (CPE) for dietetic professionals by the Commission on Dietetic Registration. It provides one hour of level 1 CPE credit for dietetic professionals. The full text of the module is in the notes section of each page, and is accompanied by summary points and/or visuals in the box at the top of the page. Directions for obtaining CPE are provided at the end of the module. 2 After completing this module, dietetic professionals will be able to: • Define polyols. • Identify the various types of polyols found in foods. • Understand the uses and health effects of polyols in foods. • Counsel clients on how to incorporate polyols into an overall healthful eating pattern. 3 4 Polyols are carbohydrates that are hydrogenated, meaning that a hydroxyl group replaces the aldehyde or ketone group found on sugars. Hydrogenated monosaccharides include erythritol, xylitol, sorbitol, and mannitol. Hydrogenated disaccharides include lactitol, isomalt, and maltitol. And hydrogenated starch hydrolysates (HSH), or polyglycitols (a wide range of corn syrups and maltodextrins), are formed from polysaccharides (Grabitske and Slavin 2008). 5 Nearly 54 percent of Americans are trying to lose weight, more than ever before. Increasingly, they are turning toward no- and low-sugar, and reduced calorie, foods and beverages to help them achieve their weight loss goals (78% of Americans who are trying to lose weight) (CCC 2010). Polyols, found in many of these foods, are becoming a subject of more interest. 6 They are incompletely digested , therefore are sometimes referred to as “low- digestible carbohydrates.” Polyols are not calorie free, as there is some degree of digestion and absorption of the carbohydrate. -
![United States Patent 1191 Lll] 3,983,266 Bahls [451 Sept](https://docslib.b-cdn.net/cover/8181/united-states-patent-1191-lll-3-983-266-bahls-451-sept-158181.webp)
United States Patent 1191 Lll] 3,983,266 Bahls [451 Sept
United States Patent 1191 lll] 3,983,266 Bahls [451 Sept. 28, 1976 [54] METHOD FOR APPLYING METALLIC 3.776.740 [2/1973 Sivcrz ct al. .......................... .. l06/l SILVER TO A SUBSTRATE OTHER PUBLICATIONS [75] Inventor: Harry Bahls, Wayne, Pa. lvanov et al., Chem. Abs. 43:2548c, I949, [73] Assignee: Peacock Laboratories, Inc., Philadelphia, Pa. Primary Examiner-Ralph S. Kendall [22] Filed: Oct. 9, I974 I 57] ABSTRACT [2!] ,Appl. No.: 513,417 High efficiency deposition of silver on the surface of a substrate is obtained by providing a solution contain [52] [1.8. CI ............................... .. 427/164; 427/165; ing reducible dissolved silver in the presence of an al 427/168; 427/424; 427/426; l06/l kali metal hydroxide and ammonia, all of which are [51] Int. CLZ. ......................................... .. C23C 3/02 applied to the substrate in the presence of an aqueous [58] Field of Search .............. .. l06/l; 427/l68. I69, solution of a moderating reducer containing :1 poly 427/165, I64, 426, 304, 125, 425 hydric alcohol of the formula CH2OH(CHOH),,C H,OH, where n is an integer from 1 to 6. Preferably [56] References Cited the polyhydric alcohol is sorbitol, and in a preferred UNITED STATES PATENTS embodiment a moderator is the form of a thio glycerol is present. 2,996,406 8/l96l Weinrich ........... ............ .. 427/168 3,772,078 ll/l973 Polichcttc ct al ................. .. l06/l X l5 Claims, No Drawings 3,983,266 1 Other objects and advantages of this invention, in METHOD FOR APPLYING METALLIC SILVER TO cluding the economy of the same, and the case with A SUBSTRATE which it may be applied to existing silver coating equip ment and apparatus, will further become apparent BRIEF SUMMARY OF THE INVENTION 5 hereinafter. -
US EPA Inert (Other) Pesticide Ingredients
U.S. Environmental Protection Agency Office of Pesticide Programs List of Inert Pesticide Ingredients List 3 - Inerts of unknown toxicity - By Chemical Name UpdatedAugust 2004 Inert Ingredients Ordered Alphabetically by Chemical Name - List 3 Updated August 2004 CAS PREFIX NAME List No. 6798-76-1 Abietic acid, zinc salt 3 14351-66-7 Abietic acids, sodium salts 3 123-86-4 Acetic acid, butyl ester 3 108419-35-8 Acetic acid, C11-14 branched, alkyl ester 3 90438-79-2 Acetic acid, C6-8-branched alkyl esters 3 108419-32-5 Acetic acid, C7-9 branched, alkyl ester C8-rich 3 2016-56-0 Acetic acid, dodecylamine salt 3 110-19-0 Acetic acid, isobutyl ester 3 141-97-9 Acetoacetic acid, ethyl ester 3 93-08-3 2'- Acetonaphthone 3 67-64-1 Acetone 3 828-00-2 6- Acetoxy-2,4-dimethyl-m-dioxane 3 32388-55-9 Acetyl cedrene 3 1506-02-1 6- Acetyl-1,1,2,4,4,7-hexamethyl tetralin 3 21145-77-7 Acetyl-1,1,3,4,4,6-hexamethyltetralin 3 61788-48-5 Acetylated lanolin 3 74-86-2 Acetylene 3 141754-64-5 Acrylic acid, isopropanol telomer, ammonium salt 3 25136-75-8 Acrylic acid, polymer with acrylamide and diallyldimethylam 3 25084-90-6 Acrylic acid, t-butyl ester, polymer with ethylene 3 25036-25-3 Acrylonitrile-methyl methacrylate-vinylidene chloride copoly 3 1406-16-2 Activated ergosterol 3 124-04-9 Adipic acid 3 9010-89-3 Adipic acid, polymer with diethylene glycol 3 9002-18-0 Agar 3 61791-56-8 beta- Alanine, N-(2-carboxyethyl)-, N-tallow alkyl derivs., disodium3 14960-06-6 beta- Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt 3 Alanine, N-coco alkyl derivs. -
Biochemistry Lab (BT35L) Lab Manual
Department of Biotechnology Sri Jayachamarajendra College of Engineering Mysuru-570006 Biochemistry Lab (BT35L) Lab Manual (Prepared by Dr. S. Nanjunda Swamy and Dr. M. N. Nagendra Prasad) INDEX 1. PREPARATION OF SODIUM ACETATE BUFFER 2. ESTIMATION OF GLUCOSE BY DNS METHOD 3. ESTIMATION OF SAPONIFICATION VALUE OF FATS/OILS 4. ESTIMATION OF ACID VALUE OF FATS/OILS 5. PREPARATION OF PHOSPHOTIDYL CHOLINE FROM EGG YOLK 6. LOWRY METHOD FOR PROTEIN ESTIMATION 7. ESTIMATION OF AMINO ACID BY FORMAL TITRATION 8. DETERMINATION OF ISOELECTRIC POINT OF GLYCINE (PI) 9. SEPARATION OF AMINO ACIDS BY CIRCLULAR PAPER CHROMATOGRAPHY 10. ESTIMATION OF IRON BY WONG’S METHOD Experiment No 1: PREPARATION OF SODIUM ACETATE BUFFER Aim: Preparation of sodium acetate buffer of 0.1M and 4.7 pH (25ml) Principle: Buffer is a solution used to maintain the pH of any biochemical reaction. Procedure: 1. Weigh about 0.205g of sodium acetate. Dissolve it in 15ml distilled water. 2. Dip the electrode of the pre calibrated pH meter in the above solution. 3. Add acetic acid of 0.5M drop by drop till the pH reaches 4.7. 4. Make up the solution to 25ml with distilled water. 5. Store the buffer in a sealed container. Experiment No 2: ESTIMATION OF GLUCOSE BY DNS METHOD Aim: To estimate the amount of glucose in the given ample by DNS method. Principle: This method tests for the presence of free carbonyl group (C=O), of the reducing sugars. The reaction involves the oxidation of this of free carbonyl group (aldehyde functional group present in, glucose and the ketone functional group in fructose) and simultaneous reduction of , 3,5-dinitrosalicylic acid to 3-amino,5- nitrosalicylic acid (a coloured molecule) under alkaline conditions. -
Dental and Metabolic Effects of Lactitol in the Diet of Laboratory Rats
Downloaded from British Journal of Nutrition (1989), 61, 17-24 17 https://www.cambridge.org/core Dental and metabolic effects of lactitol in the diet of labolratory rats BY T. H. GRENBY AND A. PHILLIPS Department of Oral Medicine and Pathology, United Medical and Dental Schools, Guy’s Hospital, London SEI 9RT . IP address: (Received 17 May 1988 - Accepted 30 August 1988) 170.106.35.93 I. Because so little is known about the properties of lactitol as a possible alternative bulk sweetener to sucrose, it was tested in two large-scale experiments in laboratory rats. Matched groups of caries-active Osborne-Mendel rats were fed.on uniform diets containing lactitol and compared with a sucrose control in both experiments, plus a xylitol control in the first experiment. , on 2. In the early stages of the experiments weight gains and food utilization were better on the Sucrose than on 26 Sep 2021 at 05:12:03 the lactitol regimens. Body-fat storage was higher on the sucrose than on the polyol regimens. 3. At the end of 8 weeks the mandibular molars were examined for dental plaque accumulation and dental caries. The dental caries scores when 160 g sucrose/kg in the diet was replaced by lactitol were lower by a highly significant margin, bringing them down to the same low level as those on a 160 g xylitol/kg regimen. 4. Testing lactitol in a manufactured food product, shortbread biscuits, in comparison with ordinary sucrose biscuits, showed differences in plaque scores (significant) and caries levels (highly significant), with 60 % fewer lesions on the lactitol regimen. -
Polyols Have a Variety of Functional Properties That Make Them Useful Alternatives to Sugars in Applications Including Baked Goods
Polyols have a variety of functional properties that make them useful alternatives to sugars in applications including baked goods. Photo © iStockphoto.com/Synergee pg 22 09.12 • www.ift.org BY LYN NABORS and THERESA HEDRICK SUGAR REDUCTION WITH Polyols Polyols are in a unique position to assist with reduced-sugar or sugar-free reformulations since they can reduce calories and complement sugar’s functionality. ugar reduction will be an important goal over the of the product’s original characteristics may still be main- next few years as consumers, government, and in- tained with the replacement of those sugars by polyols. Sdustry alike have expressed interest in lower-calorie In addition, excellent, good-tasting sugar-free products and lower-sugar foods. The 2010 Dietary Guidelines for can be developed by using polyols. Polyols are in a unique Americans put a strong emphasis on consuming fewer position to assist with reduced-sugar or sugar-free refor- calories and reducing intake of added sugars. The In- mulations; since they are only partially digested and ab- stitute of Medicine (IOM) held a public workshop in sorbed, they can reduce calories and complement sugar’s November 2010 to discuss ways the food industry can functionality. Polyols provide the same bulk as sugars and use contemporary and innovative food processing tech- other carbohydrates. Additionally, polyols have a clean, nologies to reduce calorie intake in an effort to reduce sweet taste, which is important since consumers are not and prevent obesity, and in October 2011 recommended likely to sacrifice taste for perceived health benefits. Poly- front-of-package labeling that includes rating the product ols have a host of other functional properties that make based on added sugars content. -
S. 1110, the Engine Coolant and Antifreeze Bittering Agent Act of 2005
S. HRG. 109–377 S. 1110, THE ENGINE COOLANT AND ANTIFREEZE BITTERING AGENT ACT OF 2005 HEARING BEFORE THE SUBCOMMITTEE ON CONSUMER AFFAIRS, PRODUCT SAFETY, AND INSURANCE OF THE COMMITTEE ON COMMERCE, SCIENCE, AND TRANSPORTATION UNITED STATES SENATE ONE HUNDRED NINTH CONGRESS FIRST SESSION JULY 18, 2005 Printed for the use of the Committee on Commerce, Science, and Transportation ( U.S. GOVERNMENT PRINTING OFFICE 27–356 PDF WASHINGTON : 2006 For sale by the Superintendent of Documents, U.S. Government Printing Office Internet: bookstore.gpo.gov Phone: toll free (866) 512–1800; DC area (202) 512–1800 Fax: (202) 512–2250 Mail: Stop SSOP, Washington, DC 20402–0001 VerDate 0ct 09 2002 12:59 May 08, 2006 Jkt 027356 PO 00000 Frm 00001 Fmt 5011 Sfmt 5011 S:\WPSHR\GPO\DOCS\27356.TXT JACKF PsN: JACKF SENATE COMMITTEE ON COMMERCE, SCIENCE, AND TRANSPORTATION ONE HUNDRED NINTH CONGRESS FIRST SESSION TED STEVENS, Alaska, Chairman JOHN MCCAIN, Arizona DANIEL K. INOUYE, Hawaii, Co-Chairman CONRAD BURNS, Montana JOHN D. ROCKEFELLER IV, West Virginia TRENT LOTT, Mississippi JOHN F. KERRY, Massachusetts KAY BAILEY HUTCHISON, Texas BYRON L. DORGAN, North Dakota OLYMPIA J. SNOWE, Maine BARBARA BOXER, California GORDON H. SMITH, Oregon BILL NELSON, Florida JOHN ENSIGN, Nevada MARIA CANTWELL, Washington GEORGE ALLEN, Virginia FRANK R. LAUTENBERG, New Jersey JOHN E. SUNUNU, New Hampshire E. BENJAMIN NELSON, Nebraska JIM DEMINT, South Carolina MARK PRYOR, Arkansas DAVID VITTER, Louisiana LISA J. SUTHERLAND, Republican Staff Director CHRISTINE DRAGER KURTH, Republican Deputy Staff Director DAVID RUSSELL, Republican Chief Counsel MARGARET L. CUMMISKY, Democratic Staff Director and Chief Counsel SAMUEL E. -
Sweet Sensations by Judie Bizzozero | Senior Editor
[Confections] July 2015 Sweet Sensations By Judie Bizzozero | Senior Editor By R.J. Foster, Contributing Editor For many, terms like “reduced-sugar” or “sugar-free” do not go with the word “candy.” And yet, the confectionery industry is facing growing demand for treats that offer the taste people have grown to love without the adverse health effects they’re looking to avoid. Thankfully, there is a growing palette of ingredients from which candy makers can paint a new picture of sweetness that will be appreciated by the even most discerning of confectionery critics. SUGAR ALCOHOLS Also referred to as polyols, sugar alcohols are a common ingredient in reduced-sugar and sugar-free applications, especially confections. Funny thing, they’re not sugars or alcohols. Carbohydrate chains composed of monomeric, dimeric and polymeric units, polyols resemble both sugars and alcohols, but do not contain an ethanol molecule. All but two sugar alcohols are less sweet than sugar. Being only partially digestible, though, replacing a portion of a formulation’s sugar with a sugar alcohol reduces total calories without losing bulk (which can occur when replacing sugar with high-intensity sweeteners). Unique flavoring, texturizing and moisture-controlling effects also make polyols well-suited for confectionery products. Two very common and very similar monomeric polyols are sorbitol and mannitol. Present in a variety of fruits and vegetables, both are derived from products of cornstarch hydrolysis. Sorbitol is made via hydrogenation of glucose, which is why sorbitol is sometimes referred to as glucitol. Mannitol is created when fructose hydrogenation converts fructose into mannose, for which the final product, mannitol, is named. -
Denatonium Capsaicinate and Methods of Producing the Same
Europäisches Patentamt *EP001015418B1* (19) European Patent Office Office européen des brevets (11) EP 1 015 418 B1 (12) EUROPEAN PATENT SPECIFICATION (45) Date of publication and mention (51) Int Cl.7: C07C 237/04, A01N 37/44, of the grant of the patent: A61K 31/165, C09D 7/12 26.05.2004 Bulletin 2004/22 (86) International application number: (21) Application number: 98937289.1 PCT/US1998/015836 (22) Date of filing: 31.07.1998 (87) International publication number: WO 1999/015495 (01.04.1999 Gazette 1999/13) (54) DENATONIUM CAPSAICINATE AND METHODS OF PRODUCING THE SAME DENATONIUM CAPSAICINAT UND VERFAHREN ZU IHRER HERSTELLUNG DENATONIUM CAPSAICINATE ET SES METHODES DE PRODUCTION (84) Designated Contracting States: • ROITBERG, Michael AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU Highland Park, NJ 08904 (US) MC NL PT SE (74) Representative: Guerre, Dominique et al (30) Priority: 19.09.1997 US 929621 Cabinet Germain et Maureau, 12, rue Boileau, (43) Date of publication of application: BP 6153 05.07.2000 Bulletin 2000/27 69466 Lyon Cedex 06 (FR) (73) Proprietor: Burlington Bio-Medical & Scientific (56) References cited: Corp. EP-A- 0 458 177 WO-A-94/02558 Farmingdale, NY 11735-1718 (US) GB-A- 2 097 791 US-A- 4 005 038 US-A- 4 661 504 US-A- 4 997 853 (72) Inventors: US-A- 5 008 289 • BLUM, Melvin Wantagh, NY 11794 (US) Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. -
Lactitol, Bulk Sweetener for Sugar Free and Reduced Calories Hard
Sugar Free Dental Properties Lactitol is noncariogenic. It is not fermented by the oral micro flora, so its consumption does not lead to Lactitol, Bulk Sweetener for the formation of acids that deminer- alize the tooth enamel. Also, the building up of tooth plaque is much less for lactitol-containing hard can- dies when compared to sugar. Its Sugar Free and Reduced noncariogenic properties have been shown in various clinical trials (Grenby and Desai, 1988; Grenby, 1989; Grenby and Phillips, 1989; Grenby et al., 1989; van der Calories Hard Candy Hoeven, 1986). REGULATORY ASPECTS A self-affirmation petition for the Generally Recognized as Safe status of lactitol, submitted by Purac, was his paper will discuss the prop- intense sweetener like aspartame or accepted for filing by the Food and Terties, regulatory aspects, and acesulfame-K. The taste, sweetening power, and Drug Administration in September applications of lactitol in hard can- 1993. The safety of lactitol has been dies. Lactitol is a disaccharide sugar profile of such sweetener combina- tions are very close to those of substantiated by numerous animal alcohol made from lactose by cat- and human studies. This safety alytic hydrogenation. sucrose. Its clean sweet taste allows a superb flavor release. research has been reviewed by sev- eral international authoritative bod- BENEFITS OF LACTITOL Reduced Calories ies (JEFCA, 1983; EEC, 1984). The Taste The FDA allows the use of a self- joint FAO/WHO Committee on Lactitol has a clean, sweet, sugar- determined value of 2.0 kilocalorie Food Additives has approved lacti- like taste without an aftertaste. The per gram for lactitol. -
Disposal of Solid Chemicals in the Normal Trash
Disposal of Solid Chemicals in the Normal Trash Many solid chemicals can be safety discarded into the normal trash, provided they are in containers that are not broken or cracked and have tightly fitting caps. These chemicals are considered acceptable for ordinary disposal because they display none of the properties of hazardous waste, are of low acute toxicity, and have not been identified as having any chronic toxic effects as summarized in the National Institute of Occupational Safety and Health (NIOSH) “Registry of Toxic Effects of Chemical Substances”. Examples of chemicals acceptable for disposal as regular trash are listed below. To dispose of these chemicals, place the containers in a box lined with a plastic bag, tape the top of the box shut, write “Normal Trash” on the box and then place the box next to the lab trash container. Only solid forms of these chemicals can be disposed in this manner. Any questions about these chemicals or other chemicals that may be disposed of in the normal trash should be directed to the Hazardous Materials Technician (610) 330-5225. Chemicals Generally Acceptable for Disposal as Regular Trash Acacia powder, gum Detergent (most) Methyl salicylate Sodium carbonate arabic Cation exchange resins Methylene blue Sodium chloride Acid, Ascorbic Chromatographic Methyl stearate Sodium citrate Acid, Benzoic absorbents Nutrient agar Sodium dodecyl sulfate Acid, Boric Crystal violet Octacosane (SDS) Acid, Casamind Dextrin Parafin Sodium formate Acid, Citric Dextrose Pepsin Sodium iodide Acid, Lactic Diatomaceous -
Dietary Supplements Compendium Volume 1
2015 Dietary Supplements Compendium DSC Volume 1 General Notices and Requirements USP–NF General Chapters USP–NF Dietary Supplement Monographs USP–NF Excipient Monographs FCC General Provisions FCC Monographs FCC Identity Standards FCC Appendices Reagents, Indicators, and Solutions Reference Tables DSC217M_DSCVol1_Title_2015-01_V3.indd 1 2/2/15 12:18 PM 2 Notice and Warning Concerning U.S. Patent or Trademark Rights The inclusion in the USP Dietary Supplements Compendium of a monograph on any dietary supplement in respect to which patent or trademark rights may exist shall not be deemed, and is not intended as, a grant of, or authority to exercise, any right or privilege protected by such patent or trademark. All such rights and privileges are vested in the patent or trademark owner, and no other person may exercise the same without express permission, authority, or license secured from such patent or trademark owner. Concerning Use of the USP Dietary Supplements Compendium Attention is called to the fact that USP Dietary Supplements Compendium text is fully copyrighted. Authors and others wishing to use portions of the text should request permission to do so from the Legal Department of the United States Pharmacopeial Convention. Copyright © 2015 The United States Pharmacopeial Convention ISBN: 978-1-936424-41-2 12601 Twinbrook Parkway, Rockville, MD 20852 All rights reserved. DSC Contents iii Contents USP Dietary Supplements Compendium Volume 1 Volume 2 Members . v. Preface . v Mission and Preface . 1 Dietary Supplements Admission Evaluations . 1. General Notices and Requirements . 9 USP Dietary Supplement Verification Program . .205 USP–NF General Chapters . 25 Dietary Supplements Regulatory USP–NF Dietary Supplement Monographs .