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G2 Phase Cell Cycle Regulation by E2F4 Following Genotoxic Stress
G2 Phase Cell Cycle Regulation by E2F4 Following Genotoxic Stress by MEREDITH ELLEN CROSBY Submitted in partial fulfillment of the requirements for the Degree of Doctor of Philosophy Thesis Advisor: Dr. Alex Almasan Department of Environmental Health Sciences CASE WESTERN RESERVE UNIVERSITY May, 2006 CASE WESTERN RESERVE UNIVERSITY SCHOOL OF GRADUATE STUDIES We hereby approve the dissertation of ______________________________________________________ candidate for the Ph.D. degree *. (signed)_______________________________________________ (chair of the committee) ________________________________________________ ________________________________________________ ________________________________________________ ________________________________________________ ________________________________________________ (date) _______________________ *We also certify that written approval has been obtained for any proprietary material contained therein. TABLE OF CONTENTS TABLE OF CONTENTS………………………………………………………………….1 LIST OF FIGURES……………………………………………………………………….5 LIST OF TABLES………………………………………………………………………...7 ACKNOWLEDGEMENTS……………………………………………………………….8 LIST OF ABBREVIATIONS……………………………………………………………10 ABSTRACT……………………………………………………………………………...15 CHAPTER 1. INTRODUCTION 1.1. CELL CYCLE REGULATION: HISTORICAL OVERVIEW………………...17 1.2. THE E2F FAMILY OF TRANSCRIPTION FACTORS……………………….22 1.3. E2F AND CELL CYCLE CONTROL 1.3.1. G0/G1 Phase Transition………………………………………………….28 1.3.2. S Phase…………………………………………………………………...28 1.3.3. G2/M Phase Transition…………………………………………………..30 1.4. -
Individual Index
INDIVIDUAL INDEX Bl Page Page A Cooremans-Cruz, Eugenio Juan 3825 Cortes, Eugenia 2474 Abbott, Charles P 3807 Crowley, Daniel 3820 Abrams, Samuel S 3825 Cruz, Marinelle Khristy 3836 Abshire, Arthur J 3812 Cuervo, Ester 3825 Ah Kwang Chang 3827 Cuffy, Jackson Ormiston Edwards and Ah Sing Ying 3826 Merle Cleopatra Edwards 38J54 Ah Young Cho Kwak 3803 Alcala-Salcedo, Apolinario 3825 D Alvarado, Irma Victoria Bolarte 3853 Araujo,Lilia 3828 D'Souza, Eustace John 3824 Araujo, Maria Freitas 3825 Datronics Engineers, Inc 3857 Arellano, Santos Marquez 3830 Daves, Gary 3862 Armstrong, Anne L 235 Davies, Mrs. Olive M.V.T., Samira Arriola, Rodolfo N 3851 D.K., Ola-Tomi K., Ola-Yinka K., Asencio-Placencio, Pedro 3825 Ilesha E.K., and Baba-Tunji K 3803 Atherley, Juana Todd 3829 Davis, Jefferson F 1304 Austin, John P 234 Day, Craig 3824 DeBravo, Cenovia Mesa 3825 B DeLuna-Segovia, Jose 3825 Dibben, James William 3823 Bader, Louis William 3825 Din, Ruben P 3831 Baglieri, George 3825 Do Sook Park 3841 Bakierowska, Kazimiera 3827 Dom Min Lee 3826 Bally, George Ally 3827 Dowd, Kazuko Nishioka 3820 Barengo, Bernardino 2485 Barrera-Cabrera, Jesus 3825 Batavia Turf Farms, Inc 3818 • ^- • E Benney, Donna Marainne 3836 Eaker, Lt. Gen. IraC 1060 Berger, Harry 3825 Eha,Elmar 3825 Binabise, Juanita 3840 Ehard,Karin 3858 Birely, Victor M 1643 Elder, William J 3814 Blakeley, Hildegard G 3845 Emde, Noel Abueg 3837 Blanquicett, Carmen Cecilia 3859 Encomienda, Rogelio M 3853 Bonderenko, Edward J 2485 Espenueva, Edmundo Alfredo Boone, Master Sgt. William E 3813 Oreiro -
Obituaries Buffalo News 2010 by Name
Obituaries as found in the Buffalo News: 2010 Date of Place of Date, Page of Last Name/Maiden First Name M.I. Age Death Death/Birth/Residence Date, Page detailed obit Abbarno Vincent "Lolly" A. 9/26/2010 Kenmore, NY 9-30-2010: C4 Abbatte/Saunders Murielle A. 87 1/11/2010 1-13-2010: B4 Abbo Joseph D. 57 5/31/2010 Lewiston, NY 6-3-2010: B4 Brooksville, FL; formerly of Abbott Casimer "Casey" 12/19/22009 Cheektowaga, NY 4-18-2010: C6 Abbott Phillip C. 3/31/2010 4-3-2010: B4 Abbott Stephen E. 7/6/2010 7-8-2010: B4 Abbott/Pfoetsch Barbara J. 4/20/2010 5-2-2010: B4 Abeles Esther 95 1/31/2010 2-4-2010: C4 Abelson Gerald A. 82 2/1/2010 Buffalo, NY 2-3-2010: B4 Abraham Frank J. 94 3/21/2010 3-23-2010: B4 Abrahams/Gichtin Sonia 2/10/2010 died in California 2-14-2010: C4 Abramo Rafeala 93 12/16/2010 12-19-2010: C4 Abrams Charlotte 4/6/2010 4-8-2010: B4 Abrams S. "Michelle" M. 37 5/21/2010 Salamanca, NY 5-23-2010: B4 Abrams Walter I. 5/15/2010 Basom, NY 5-19-2010: B4 Abrosette/Aksterowicz Sister Mary 6/18/2010 6-19-2010: C4 Refer to BEN 2-21-2010: B6/7/8 for more possible Abshagen Charles, Jr. L. 73 2/19/2010 North Tonawanda, NY 2-22-2010: B8 information Acevedo Miguel A. 10/6/2010 Buffalo, NY 10-27-2010: B4 Achkar John E. -
Men Final Entries
Final Entries - Athletes List by event European Athletics Indoor Championships 2021, Torun/POL Tot. Number of countries Tot. Number of athletes Tot. Number of Men Tot. Number of Women 47 733 405 328 FINAL ENTRIES - Men 60m Senior Men Num. of countries: 33 Num. of athletes: 71 Member Federation Surname First Name DoB PB SB ARM Donigian Alexander 20/10/1993 6.64i 6.79i ART Keletela Dorian Celeste 06/02/1999 6.79i 6.85i AUT Fuchs Markus 14/11/1995 6.62i 6.69i BEL Kuba Di-Vita Gaylord 17/11/1995 6.73i 6.75i BEL Vleminckx Kobe 31/05/1998 6.65i 6.65i BLR Bliznets Dzianis 12/03/1995 6.75i 6.75i BLR Bohdan Maksim 19/03/1997 6.77i 6.77i BLR Zabalotny Yury 24/02/1997 6.72i 6.72i BUL Dimitrov Denis 10/02/1994 6.65i 6.73i BUL Jivkov Vesselin 26/01/2001 6.76i 6.80i CZE Hampl Štěpán 10/11/1999 6.70i 6.70i CZE Stromšík Zdeněk 25/11/1994 6.60i 6.68i CZE Veleba Jan 06/12/1986 6.65i 6.65i DEN Hansen Simon 30/06/1998 6.75i 6.75i DEN Kjær Emil Mader 20/12/1999 6.77i 6.77i DEN Musah Kojo 15/04/1996 6.61i 6.61i ESP López Sergio 05/07/1999 6.67i 6.74i ESP Rodríguez Daniel 26/01/1995 6.67i 6.67i ESP Sanchez Ricardo 10/08/1999 6.75i 6.75i EST Nazarov Karl Erik 17/03/1999 6.63i 6.63i FIN Illukka Riku 21/09/1999 6.73i 6.73i FIN Purola Samuel 19/05/2000 6.67i 6.67i FIN Samuelsson Samuli 23/06/1995 6.66i 6.66i FRA Fall Mouhamadou 25/02/1992 6.62i 6.62i FRA Golitin Amaury 28/01/1997 6.62i 6.62i GBR Aikines-Aryeetey Harry 29/08/1988 6.55i 6.67i GBR Bromby Oliver 30/03/1998 6.63i 6.65i GBR Robertson Andrew 17/12/1990 6.54i 6.61i GER Corucle Philipp 18/07/1997 6.62i -
THE NAMES LIST Version 7.2 -.:: GEOCITIES.Ws
List of Names, Vers. 7.2 THE NAMES LIST Version 7.2 We apologize if any names are misspelled, misplaced or in any other way misused – we can’t know everything! Shorter versions and/or nicknames are listed as Name (Short version) Some names are listed with their meaning in English as Name=english word All firstnames marked with an * are rather old-fashioned and not common among younger people any more. The surnames marked with an ** are names of prominent persons which are actually very rare. CONTEMPORARY NAMES (Bear in mind that several countries, China to name one, list surnames/family names before firstnames/personal names!) Song Abdullah African Surnames Songo’O Achmed Tchami Ahmet Adepoju Tchango Akif Amokachi Tchoutang Ali Amunike Tinkler Arif Andem Tovey Aykut Angibeaud Bahri Ardense Bekir Babayaro Arabian Female Firstnames Bülent Baruwa Aynur Durmus Billong Ayse Dursun Dosu Aysel Erdal Ekoku Belkis Erkan Etamé Berna Erol Finidi Cigdem Fahri Foe Damla Gazi Ikpeba Demet Halifi Ipoua Derya Halil Issa Dilek Hamza Kalla Elif Hassan Kanu Elo Hüsein Khumaleo Fahrie Iskender Kipketer Fatima Ismail Lobé Fatma Ismet M’butu Fehime Khalib Mapela Gulizar Khaled Masinga Gülcan Leyla Mboma Hacer Mehmet Mimboe Hatice Yusuf Moeti Hazel Zeki Moshoeu Hediye Ziya Motaung Hüeyla Moukoko Makbule Obafemi Medine Arabian Surnames Ohenen Mürüret Al - Okechukwu Nazli Okocha Shahrzad Abedzadeh Okpara Tanzu Al Awad Olembé Al Daeya Oliseh Arabian Male Firstnames Al Dokhy Opakuru Al Dossari Abdul Redebe Al Dossary Compiled By Krikkit Gamblers Page 1 List of Names, -
Durham E-Theses
Durham E-Theses Elemental Fluorine for the Greener Synthesis of Life-Science Building Blocks HARSANYI, ANTAL How to cite: HARSANYI, ANTAL (2016) Elemental Fluorine for the Greener Synthesis of Life-Science Building Blocks, Durham theses, Durham University. Available at Durham E-Theses Online: http://etheses.dur.ac.uk/11705/ Use policy The full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that: • a full bibliographic reference is made to the original source • a link is made to the metadata record in Durham E-Theses • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders. Please consult the full Durham E-Theses policy for further details. Academic Support Oce, Durham University, University Oce, Old Elvet, Durham DH1 3HP e-mail: [email protected] Tel: +44 0191 334 6107 http://etheses.dur.ac.uk 2 Durham University A thesis entitled Elemental Fluorine for the Greener Synthesis of Life-Science Building Blocks by Antal Harsanyi (College of St. Hild and St. Bede) A candidate for the degree of Doctor of Philosophy Department of Chemistry, Durham University 2016 Antal Harsanyi: Elemental fluorine for the greener synthesis of life-science building blocks Abstract Fluorinated organic compounds are increasingly important in many areas of our modern lives, especially in pharmaceutical and agrochemical applications where the incorporation of this element can have a major influence on biochemical properties. -
2013 Kaiser Permanente-Authored Publications Alphabetical by Author
2013 Kaiser Permanente-Authored Publications Alphabetical by Author 1. Abbas MA, Cannom RR, Chiu VY, Burchette RJ, Radner GW, Haigh PI, Etzioni DA Triage of patients with acute diverticulitis: are some inpatients candidates for outpatient treatment? Colorectal Dis. 2013 Apr;15(4):451-7. Southern California 23061533 KP author(s): Abbas, Maher A; Chiu, Vicki Y; Burchette, Raoul J; Radner, Gary W; Haigh, Philip I 2. Abbass MA, Slezak JM, DiFronzo LA Predictors of Early Postoperative Outcomes in 375 Consecutive Hepatectomies: A Single- institution Experience Am Surg. 2013 Oct;79(10):961-7. Southern California 24160779 KP author(s): Abbass, Mohammad Ali; Slezak, Jeffrey M; DiFronzo, Andrew L 3. Abbenhardt C, Poole EM, Kulmacz RJ, Xiao L, Curtin K, Galbraith RL, Duggan D, Hsu L, Makar KW, Caan BJ, Koepl L, Owen RW, Scherer D, Carlson CS, Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO) and CCFR, Potter JD, Slattery ML, Ulrich CM Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia Int J Mol Epidemiol Genet. 2013 Sep 12;4(3):140-9. Northern California 24046806 KP author(s): Caan, Bette 4. Aberg JA, Gallant JE, Ghanem KG, Emmanuel P, Zingman BS, Horberg MA Primary Care Guidelines for the Management of Persons Infected With HIV: 2013 Update by the HIV Medicine Association of the Infectious Diseases Society of America Clin Infect Dis. 2013 Nov 13. Mid-Atlantic 24235263 KP author(s): Horberg, Michael 5. Abraham AG, D'Souza G, Jing Y, Gange SJ, Sterling TR, Silverberg MJ, Saag MS, Rourke SB, Rachlis A, Napravnik S, Moore RD, Klein MB, Kitahata MM, Kirk GD, Hogg RS, Hessol NA, Goedert JJ, Gill MJ, Gebo KA, Eron JJ, Engels EA, Dubrow R, Crane HM, Brooks JT, Bosch RJ, Strickler HD, North American AIDS Cohort Collaboration on Research and Design of IeDEA Invasive cervical cancer risk among HIV-infected women: A North American multi-cohort collaboration prospective study J Acquir Immune Defic Syndr. -
World Ratings Draughts
FMJD Rating No 83 January/March 2015 FMJD rating Nr 83 January 2015 email: [email protected] 1 FMJD Rating No 83 January/March 2015 With any question concerning this issue You can contact me directly via email: [email protected] 2 FMJD Rating No 83 January/March 2015 1. Rating - open Name Nationality Title Rating +/- 1 = shvartsman alexander Russia gmi 2425 -19 2 = georgiev alexander Russia gmi 2421 -15 3 +5 chizhov alexey Russia gmi 2409 +18 4 = getmanski alexander Russia gmi 2404 +4 5 +1 boomstra roel Netherlands gmi 2399 +4 6 -3 baliakin alexander Netherlands gmi 2396 -11 7 = gantvarg anatoli Belarus gmi 2393 +1 8 -3 valneris guntis Latvia gmi 2388 -9 9 +2 prosman erno Netherlands gmi 2378 +2 10 +2 dolfing martin Netherlands gmi 2377 +3 11 +3 shaibakov ainur Russia gmi 2373 +6 12 -2 virny vadim Germany gmi 2370 -7 13 +3 amrillaev murodullo Russia gmi 2367 +3 14 -5 meurs pim Netherlands gmi 2364 -16 15 = clerc rob Netherlands gmi 2363 -3 16 -3 ivanov artem Ukraine mi 2361 -11 17 +2 cordier arnaud France gmi 2358 +7 18 -1 ndjofang jean marc Cameroon gmi 2357 +4 19 +3 heusdens ron Netherlands gmi 2351 +3 20 +4 jansen gerard Netherlands gmi 2348 +3 21 +7 kalmakov andrej Russia gmi 2346 +5 22 +1 vermin hans Switzerland gmi 2346 = 23 -2 n'diaye macodou Senegal gmi 2344 -5 24 +5 anikeev yuriy Ukraine gmi 2343 +5 25 -7 krajenbrink johan Netherlands gmi 2341 -11 26 +1 van den akker jeroen Netherlands gmi 2339 -3 27 +3 leesmann kaido Estonia gmi 2337 = 28 +3 misans roberts Latvia mi 2336 = 29 +3 kolesov gawril Russia mi 2334 = 30 -4 vatutin evgeni -
Merck Announces U.S. FDA Approval of VERQUVO® (Vericiguat)
NEWS RELEASE Merck Announces U.S. FDA Approval of VERQUVO® (vericiguat) 1/20/2021 VERQUVO Approved for Reduction of Risk of Cardiovascular Death and Heart Failure (HF) Hospitalization Following a Hospitalization for HF or Need for Outpatient Intravenous (IV) Diuretics in Adults with Symptomatic Chronic Heart Failure and Ejection Fraction Less than 45% VERQUVO is the First Soluble Guanylate Cyclase Stimulator, Approved to Treat Heart Failure KENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved VERQUVO, a soluble guanylate cyclase (sGC) stimulator, to reduce the risk of cardiovascular death and heart failure hospitalization following a hospitalization for heart failure or need for outpatient intravenous (IV) diuretics in adults with symptomatic chronic heart failure and ejection fraction less than 45%. The approval of VERQUVO by the FDA, which is the rst treatment for chronic heart failure approved specically for patients following a hospitalization for heart failure or need for outpatient IV diuretics, is based on the results of the pivotal Phase 3 VICTORIA trial and follows a priority regulatory review. VERQUVO (vericiguat) 2.5 mg, 5 mg, and 10 mg tablets is being jointly developed with Bayer AG. The VERQUVO label contains a boxed warning that indicates that VERQUVO should not be administered to pregnant females because it may cause fetal harm. For more information, see “Selected Safety Information” below. “Patients with symptomatic chronic heart failure and reduced ejection fraction have a high risk for hospitalization after experiencing symptoms of heart failure requiring outpatient IV diuretic treatment or hospitalization. -
Treatment of Children with Pulmonary Hypertension. Expert Consensus Statement on the Diagnosis and Treatment of Paediatric Pulmonary Hypertension
Pulmonary vascular disease ORIGINAL ARTICLE Heart: first published as 10.1136/heartjnl-2015-309103 on 6 April 2016. Downloaded from Treatment of children with pulmonary hypertension. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK Georg Hansmann,1 Christian Apitz2 For numbered affiliations see ABSTRACT administration (oral, inhaled, subcutaneous and end of article. Treatment of children and adults with pulmonary intravenous). Additional drugs are expected in the Correspondence to hypertension (PH) with or without cardiac dysfunction near future. Modern drug therapy improves the Prof. Dr. Georg Hansmann, has improved in the last two decades. The so-called symptoms of PAH patients and slows down the FESC, FAHA, Department of pulmonary arterial hypertension (PAH)-specific rates of clinical deterioration. However, emerging Paediatric Cardiology and medications currently approved for therapy of adults with therapeutic strategies for adult PAH, such as Critical Care, Hannover PAH target three major pathways (endothelin, nitric upfront oral combination therapy, have not been Medical School, Carl-Neuberg- fi Str. 1, Hannover 30625, oxide, prostacyclin). Moreover, some PH centres may use suf ciently studied in children. Moreover, the com- Germany; off-label drugs for compassionate use. Pulmonary plexity of pulmonary hypertensive vascular disease [email protected] hypertensive vascular disease (PHVD) in children is (PHVD) in children makes the selection of appro- complex, and selection of appropriate therapies remains priate therapies a great challenge far away from a This paper is a product of the fi writing group of the European dif cult. In addition, paediatric PAH/PHVD therapy is mere prescription of drugs. -
World Scientists' Warning of a Climate Emergency
Supplemental File S1 for the article “World Scientists’ Warning of a Climate Emergency” published in BioScience by William J. Ripple, Christopher Wolf, Thomas M. Newsome, Phoebe Barnard, and William R. Moomaw. Contents: List of countries with scientist signatories (page 1); List of scientist signatories (pages 1-319). List of 153 countries with scientist signatories: Albania; Algeria; American Samoa; Andorra; Argentina; Australia; Austria; Bahamas (the); Bangladesh; Barbados; Belarus; Belgium; Belize; Benin; Bolivia (Plurinational State of); Botswana; Brazil; Brunei Darussalam; Bulgaria; Burkina Faso; Cambodia; Cameroon; Canada; Cayman Islands (the); Chad; Chile; China; Colombia; Congo (the Democratic Republic of the); Congo (the); Costa Rica; Côte d’Ivoire; Croatia; Cuba; Curaçao; Cyprus; Czech Republic (the); Denmark; Dominican Republic (the); Ecuador; Egypt; El Salvador; Estonia; Ethiopia; Faroe Islands (the); Fiji; Finland; France; French Guiana; French Polynesia; Georgia; Germany; Ghana; Greece; Guam; Guatemala; Guyana; Honduras; Hong Kong; Hungary; Iceland; India; Indonesia; Iran (Islamic Republic of); Iraq; Ireland; Israel; Italy; Jamaica; Japan; Jersey; Kazakhstan; Kenya; Kiribati; Korea (the Republic of); Lao People’s Democratic Republic (the); Latvia; Lebanon; Lesotho; Liberia; Liechtenstein; Lithuania; Luxembourg; Macedonia, Republic of (the former Yugoslavia); Madagascar; Malawi; Malaysia; Mali; Malta; Martinique; Mauritius; Mexico; Micronesia (Federated States of); Moldova (the Republic of); Morocco; Mozambique; Namibia; Nepal; -
Journal Officiel De La République Française
o er Quarante-troisième année. – N 231 A ISSN 0298-296X Mardi 1 décembre 2009 BODACCBULLETIN OFFICIEL DES ANNONCES CIVILES ET COMMERCIALES ANNEXÉ AU JOURNAL OFFICIEL DE LA RÉPUBLIQUE FRANÇAISE Standard......................................... 01-40-58-75-00 DIRECTION DES JOURNAUX OFFICIELS Annonces....................................... 01-40-58-77-56 Renseignements documentaires 01-40-58-79-79 26, rue Desaix, 75727 PARIS CEDEX 15 Abonnements................................. 01-40-15-67-77 www.journal-officiel.gouv.fr (8h30à 12h30) www.bodacc.fr Télécopie........................................ 01-40-15-72-75 BODACC “A” Ventes et cessions - Créations d’établissements Procédures collectives Procédures de rétablissement personnel Avis relatifs aux successions Avis aux lecteurs Les autres catégories d’insertions sont publiées dans deux autres éditions séparées selon la répartition suivante Modifications diverses..................................... $ BODACC “B” Radiations ......................................................... # Avis de dépôt des comptes des sociétés .... BODACC “C” Banque de données BODACC servie par les sociétés : Altares-D&B, EDD, Extelia, Questel, Tessi Informatique, Jurismedia, Pouey International, Scores et Décisions, Les Echos, Creditsafe, Coface services, Cartegie, La Base Marketing, Infolegale, France Telecom Orange, Telino et Maxisoft. Conformément à l’article 4 de l’arrêté du 17 mai 1984 relatif à la constitution et à la commercialisation d’une banque de données télématique des informations contenues dans le BODACC, le droit d’accès prévu par la loi no 78-17 du 6 janvier 1978 s’exerce auprès de la Direction des Journaux officiels. Le numéro : 2,50 € Abonnement. − Un an (arrêté du 21 novembre 2008 publié au Journal officiel du 27 novembre 2008) : France : 386,20 €. Pour l’expédition par voie aérienne (outre-mer) ou pour l’étranger : paiement d’un supplément modulé selon la zone de destination ; tarif sur demande Paiement à réception de facture.