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64th Annual Scientific Meeting SOCIETYFINAL FOR REPRODUCTIVE PROGRAM INVESTIGATION D2D: DATA TO DISCOVERY MARCH 15-18, 2017 HILTON ORLANDO BONNET CREEK 14100 BONNET CREEK RESORT LANE – ORLANDO, FL 32821 Continuing Medical Education credit is provided through joint providership with The American College of Obstetricians and Gynecologists. Table of Contents Message from SRI President ................................................................................................................ 3 2017 Program Committee ................................................................................................................... 4 Schedule-at-a-Glance ......................................................................................................................... 5 SRI Underrepresented Minority Program ............................................................................................. 6 About Orlando..................................................................................................................................... 7 Social Events ...................................................................................................................................... 8 Exhibitors ............................................................................................................................................ 9 Hilton Orlando Bonnet Creek Floor Plan ............................................................................................ 10 Continuing Medical Education Information ....................................................................................... 11 Scientific Program ............................................................................................................................. 12 Poster Guide ...................................................................................................................................... 51 Thank You to Our 2017 Poster Judges ................................................................................................ 87 SRI Grants Program ........................................................................................................................... 88 Save the Date: SRI-University of Edinburgh Symposium .................................................................... 89 SRI Awards ........................................................................................................................................ 90 About SRI .......................................................................................................................................... 92 SRI Council & Staff ............................................................................................................................. 94 SRI Thanks 2017 Supporters .............................................................................................................. 95 Save the Date: SRI 2018 Annual Meeting ............................................................................. Back Cover 64th SRI Annual Scientific Meeting Venue Hilton Orlando Bonnet Creek 14100 Bonnet Creek Resort Lane Orlando, FL 32821 Phone: +1-407-597-3600 Future SRI Meetings SRI 65th Annual Scientific Meeting • San Diego, CA • March 7-10, 2018 SRI 66th Annual Scientific Meeting • Paris, France • March 13-16, 2019 SRI 67th Annual Scientific Meeting • Vancouver, Canada • March 11-14, 2020 Society for Reproductive Investigation 555 East Wells Street, Suite 1100, Milwaukee, WI 53202-3823 Phone: +1-414-918-9888 • Fax: +1-414-276-3349 Email: [email protected] •Website: www.sri-online.org © Society for Reproductive Investigation. All rights reserved. SRI-0117-228 2 FINAL PROGRAM Society for Reproductive Investigation 64th Annual Scientific Meeting MARCH 15-18, 2017 ORLANDO, FL Message from SRI President Welcome Dear Colleagues: Welcome to the 64th Annual Meeting of the Society for Reproductive Investigation, March 15 - 18, 2017 in Orlando, FL. The theme of the 2017 meeting, “D2D: Data to Discovery,” was chosen to highlight new basic, translational and clinical approaches and opportunities for harnessing the power of scientific data to promote knowledge in reproductive health and medicine. Sam Mesiano, PhD, as Program Director, has created an excellent program, which includes three Presidential Distinguished Lecturers, one trainee plenary session, 24 concurrent oral sessions, 12 mini-symposia and two special symposia. In addition to the scientific sessions, we have also planned complementary events that advance the mission of SRI. The first is Connection Corners, an annual event that engages trainees with the more experienced members of the Society. We will also hold three lunch sessions – on Wednesday, we will hold a Diversity Career Development Forum; on Thursday, the topic will be Systems Biology in Pregnancy Health and Research; on Friday, the focus will be Precision Medicine and Women’s Health. Each of our three Presidential Distinguished Lectures represents a different aspect of our D2D theme. The Thursday Presidential lecturer is Suchi Saria, PhD, from the Department of Computational Sciences at Johns Hopkins University. Dr Saria is an expert in computational biology and machine learning. She applies her unique knowledge to computational health informatics and predictive modeling in healthcare. The Friday Presidential lecturer is Stephen Quake, PhD, Lee Otterson Professor in the School of Engineering and Professor of Bioengineering, Applied Physics and Physics at Stanford University. Dr Quake’s recent inventions in the area of prenatal genomics have transformed the field. He will share his innovative research and provide visionary comments about the future of blood based-genomic testing. David Haig, PhD, George Putnam Professor of Organismic and Evolutionary Biology at Harvard University, will give the Saturday Presidential lecture. Dr. Haig will talk about his novel and provocative data synthesis approaches to understanding maternal-fetal conflict. The 2017 annual meeting will be held in Orlando, FL, at the Hilton Orlando Bonnet Creek. The science will be stimulating, the camaraderie will be engaging, and the warm sun of Florida will be shining. On behalf of the SRI Council, officers and staff, I invite you to attend the exciting meeting we have planned and connect with our colleagues and friends in SRI! Yours, Yoel Sadovsky, MD, SRI President 2016-2017 FINAL PROGRAM Society for Reproductive Investigation 64th Annual Scientific Meeting MARCH 15-18, 2017 ORLANDO, FL 3 2017 Program Committee 2017 Program Committee Program Committee Chair Program Committee Co-Chair Stephen Matthews, PhD Emre Seli, MD University of Toronto Yale University 2017 Program Director Sam Mesiano, PhD Case Western Reserve University Elizabeth A. Bonney, MD, MPH Sarah England, PhD University of Vermont Washington University William H. Catherino, MD, PhD Leslie Myatt, PhD Uniformed Services University Oregon Health & Science University Marilyn Cipolla, PhD Bo Rueda, PhD University of Vermont Harvard Medical School Sandra T. Davidge, PhD Emiel Post Uiterweer, MD, PhD University of Alberta UMC Utrecht Charles Ducsay, PhD Stacy Zamudio, PhD Loma Linda University Hakensack University Yoel Sadovsky, MD Magee-Women’s Research Institute 4 FINAL PROGRAM Society for Reproductive Investigation 64th Annual Scientific Meeting MARCH 15-18, 2017 ORLANDO, FL Schedule-at-a-Glance Schedule-at-a-Glance TUESDAY, WEDNESDAY, THURSDAY, FRIDAY, SATURDAY, MARCH 14 MARCH 15 MARCH 16 MARCH 17 MARCH 18 7:00 a.m. – 7:00 p.m. 7:00 a.m. – 6:00 p.m. 7:00 a.m. – 6:30 p.m. 7:00 a.m. – 1:00 p.m. Registration Registration Registration Registration 7:30 a.m. – 8:30 a.m. 8:00 a.m. – 10:00 a.m. 7:15 a.m. – 8:00 a.m. 8:00 a.m. – 9:00 a.m. Career Development President’s Welcome SRI Business President’s Session – Mid- Address, President’s Meeting (Members Distinguished Career Researcher Distinguished only) (Breakfast Lecture III Breakfast Lecture I, New provided) 9:00 a.m. – 10:30 a.m. Investigator Plenary 8:30 a.m. – 5:00 p.m. 8:00 a.m. – 9:00 a.m. Poster Session III Satellite Meetings 10:00 a.m. – 11:30 a.m. President’s Morning 10:30 a.m. – 12:00 p.m. Poster Session I Distinguished Concurrent Oral Lecture II Presentations IV 9:15 a.m. – 10:45 a.m. Concurrent Oral Presentations II 10:45 a.m. – 12:15 p.m. Poster Session II 2:00 p.m. – 7:00 p.m. 8:30 a.m. – 5:00 p.m. 12:00 p.m. – 1:30 p.m. 12:30 p.m. – 2:00 p.m. 12:15 p.m. – 1:45 p.m. Registration Satellite Meetings Special Symposia I Special Symposia II Hot Topics & Awards Ceremony 2:00 p.m. – 6:00 p.m. 12:00 p.m. – 1:00 p.m. 12:00 p.m. – 1:30 p.m. 12:30 p.m. – 2:00 p.m. SRI Council Career Development Past President’s Pfizer – SRI (Lunch Included) Meeting Session - Diversity Lunch (Invitation President’s Awards 2:00 p.m. – 4:00 p.m. Symposium Only) Lunch (By Invitation SRI Council Meeting 12:00 p.m. – 1:00 p.m. 1:45 p.m. – 3:45 p.m. Only) Reproductive Mini Symposia I 2:15 p.m. – 3:45 p.m. Afternoon Sciences Editorial 3:45 p.m. – 4:00 p.m. Concurrent Oral Board Meeting Coffee Break Presentations III 4:00 p.m. – 6:00 p.m. 3:45 p.m. – 4:00 p.m. Concurrent Oral Coffee Break Presentations I 4:00 p.m. – 6:00 p.m. Mini Symposia II 5:15 p.m. – 6:45 p.m. 6:15 p.m. – 7:45 p.m. 6:15 p.m. – 7:45 p.m. Career Development Connection Corners Presidential Session – In – Address, Awards and Training and Early Wine and Cheese Career Researcher Reception Evening 6:45 p.m. – 8:00 p.m. Welcome Reception FINAL PROGRAM Society for Reproductive Investigation 64th Annual