For research use only For research

-10,-11,-12,-13,-14 & Active Caspases Bcl-x, Bim/Bod,Bcl-x, Mcl-1, Cytochrome c ,-5,-6,-7,-8,-9,-10 & Procaspase-3

www.mblintl.com Caspase-3 & Kits -7 Immunoassay ATP Determination Kit & ADP/ATP Ratio Assay Kit ATP Determination Kit & ADP/ATP Ratio Assay Mitochondrial Apoptosis Detection Kit TM TM TM PRODUCTS: RELATED 1. MitoCapture 3. Annexin -Cy5, V-FITC, -Cy3, -EGFP, -PE, -Biotin Kits and Bulk Reagent 4. CaspSELECT 10. Anti-Apaf-1, Bcl-2, Bad, Bax, Bid, 11. Other Apoptosis Many Related Antibodies 12. Quick Apoptotic DNA Ladder Detection Kit 13. Ready-to-use Apoptosis Inducers and Set 14. Quick Cell Proliferation Assay Kit 15. Live-Dead Cell Staining Kit 16. Tag Anti-GFP and Other Antibodies 17. Antibodies for Neuroscience 2. ApoSENSOR 5. Caspase-1,-2,-3,-5,-6,-8,-9,-10 Assay Activity Kits 6. Active Human Caspase-1,-2,-3,-4 7. Ready-to-use Caspase Inhibitors and Sets 8. Ready-to-use Caspase Substrates and Sets 9. Anti-Caspase-1,-2,-3,-4,-5,-6,-7,-8,-9, C. Avoid repeated repeated Avoid C. o g/ml). However, the the However, g/ml). μ

receptor family was recently identified was recently identified receptor family ripheral blood leukocytes (PBLs), small

111-113. aliquot and freeze at -70 :831-836. g g : 7 μ 4 H Constitution Way · Woburn, MA 01801 · Phone: 1.800.200.5459 · Fax: 781-939-6963 · 276:

Western blot analysis (1-2 (1-2 analysis blot Western human, mouse, rat rat mouse, human, Immunity Science

(199) (1997) BV-3061-3

et al. et al. C. For long term storage, C. For long term 100 100 o g affinity-purified (0.5mg/ml) rabbitpolyclonal anti-DR4 antibody in μ Pan, G., G., Pan,

FORMULATION: 100 BSA, 1% glycerol, 50% containing 7.2, pH (PBS), saline buffered phosphate azide. sodium 0.02% REACTIVITY: SPECIES STORAGE CONDITIONS: Store at -20 Death Receptor 4 (DR4) Polyclonal Antibody #: CATALOG AMOUNT: freeze/defrost cycles. DESCRIPTION BACKGROUND of Ligand Fas and TNF including cytokines certain by be induced can Apoptosis receptors, containing (DD) domain death their through TNF super-family the of the TNF and Fas. A member TNFR1 novel this for ligand The TRAIL-R1. and 4) receptor (death DR4 designated and most in expressed is DR4 TRAIL. termed and identified been has receptor death pe spleen, including tissues human the of and apoptosis mediates DR4 DR3, Fas and TNFR1, Like and thymus. intestine NFkB tissues activation and cells. in many SPECIFICITY: molecular apparent the to corresponding protein, kDa 57 a detects The antibody immunoblots. SDS-PAGE on DR4 of weight AND USAGE: APPLICATION The antibody can be used for individually. determined be should conditions optimal REFERENCES: 1. P., Schneider,