Meet the Faculty Candidates
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Elaine Fuchs
Women in Cell Science 4877 Elaine Fuchs FMW: How has your research career impacted on your personal life and vice Elaine Fuchs was born in the United versa? States and raised just outside Chicago. In 1972 she graduated with EF: My father was a geochemist who a B.S. and highest distinction in specialized in meteorites at Argonne the Chemical Sciences from the National Laboratories. My aunt, who University of Illinois. Her lived in the house next door, was a undergraduate thesis research in biologist at Argonne, and an ardent physical chemistry focused on the feminist. My sister, four years my senior, electrodiffusion of nickel through is now a neuroscientist. My mother is a quartz. She moved from Illinois to housewife, who loves gardening and Princeton University to study for her cooking and used to play piano and paint PhD in Biochemistry, investigating in oils. Growing up in such a family, and changes in bacterial cell walls during with farm fields, creeks and ponds in the sporulation in Bacillus megaterium. near vicinity, I developed a deep interest Elaine Fuchs in her lab in 1980. In 1977, she joined Howard Green, in science that has carried me through then at Massachusetts Institute my professional life. of Technology (MIT), for her If I think back to the family influences during Vietnam War protests. Although postdoctoral studies. There, she that shaped my choice of career, I my near perfect performances on tough focused on elucidating the remember that my Dad strongly physics and chemistry exams may have mechanisms underlying the balance advocated my being an elementary turned a few heads, I don’t feel that it between growth and differentiation in school teacher. -
USI2019 Usievents.Com
2019 24 25 usievents.com #USI2019 line-up Robert PLOMIN MRC Research Professor of Behavioural Genetics, Institute of Psychiatry, Psychology and Neuroscience KING’S COLLEGE LONDON THE IMPLICATIONS OF THE DNA REVOLUTION Prof. Plomin is one of the world’s top behavioral geneticists who offers a unique, insider’s view of the exciting synergies that came from combining genetics and psychology. His research shows that inherited DNA differences are the major systematic force that make us who we are as individuals. The DNA Revolution, namely using DNA to predict our psychological problems and promise from birth, calls for a radical rethink about what makes us who we are, with sweeping—and no doubt controversial—implications for the way we think about parenting, education and the events that shape our lives. A pioneer of what’s sometimes called “hereditarian” science. - The Guardian - Read Blueprint: How DNA makes us who we are Sylvia EARLE Robert Oceanographer PLOMIN © Todd Richard_ synergy productions synergy Richard_ © Todd NO WATER, NO LIFE. NO BLUE, NO GREEN Dr. Sylvia Earle is a living legend. If the celebrated oceanographer, marine biologist, explorer, author, and lecturer isn’t already your hero, allow us to enlighten you. ‘Her Deepness’ has spent nearly a year of her life underwater, logging more than 7,000 hours beneath the surface. She has led countless deep-sea expeditions, was the first female chief scientist of the National Oceanic and Atmospheric Administration, and the first human—male or female—to complete an untethered walk across the seafloor at a depth of 1,250 feet. Sylvia has been a National Geographic explorer-in-residence since 1998, and continues to share her knowledge and experiences on stage, through film, in writing, and beyond. -
Control of a Powered Ankle-Foot Prosthesis Based on a Neuromuscular Model
TNSRE – 2009-00034 1 Control of a Powered Ankle-Foot Prosthesis Based on a Neuromuscular Model Michael F. Eilenberg, Hartmut Geyer, and Hugh Herr, Member, IEEE devices permit some energy storage during controlled Abstract— Control schemes for powered ankle-foot prostheses dorsiflexion and plantar flexion, and subsequent energy rely upon fixed torque-ankle state relationships obtained from release during powered plantar flexion, much like the Achilles measurements of intact humans walking at target speeds and tendon in the intact human [3], [4]. Although this passive- across known terrains. Although effective at their intended gait elastic behavior is a good approximation to the ankle's speed and terrain, these controllers do not allow for adaptation to environmental disturbances such as speed transients and terrain function during slow walking, normal and fast walking speeds variation. Here we present an adaptive muscle-reflex controller, require the addition of external energy, and thus cannot be based on simulation studies, that utilizes an ankle plantar flexor implemented by any passive ankle-foot device [5]-[7]. This comprising a Hill-type muscle with a positive force feedback deficiency is reflected in the gait of transtibial amputees using reflex. The model's parameters were fitted to match the human passive ankle-foot prostheses. Their self-selected walking ankle’s torque-angle profile as obtained from level-ground speed is slower, and stride length shorter, than normal [8]. In walking measurements of a weight and height-matched intact subject walking at 1 m/sec. Using this single parameter set, addition, their gait is distinctly asymmetric: the range of ankle clinical trials were conducted with a transtibial amputee walking movement on the unaffected side is smaller [9], [10], while, on on level ground, ramp ascent, and ramp descent conditions. -
Schedule of C Ourses
2017–2018 Schedule of Courses Schedule The David Rockefeller Graduate Program offers a Required reading: Molecular Biology of the Cell by Bruce Alberts et al.; Molecular Cell Biology by James E. Darnell et al. selection of courses, many of which students can Recommended reading: Basic Histology by Luiz Carlos Junqueira choose based on their interests and area of thesis et al. research. Organized by Rockefeller faculty, and taught Method of evaluation: Attendance, participation in the discussions, by scientists at the top of their fields, both from within student presentations, and a final oral exam and outside of the university, these courses are designed to provide a stimulating and dynamic curriculum that Cell Cycle Control students can tailor to fit their personal goals, in FREDERICK R. CROSS and HIRONORI FUNABIKI consultation with the dean of graduate studies. This seminar explores the current understanding of eukaryotic cell cycle control. Topics include the construction of a biochemical oscillator and overall structure of cell cycle control; positive and Biochemical and Biophysical Methods negative control of DNA replication; spindle morphogenesis and function; chromosome cohesion control; surveillance mechanisms SETH A. DARST and MICHAEL P. ROUT (checkpoints) monitoring spindle and DNA integrity; and control of This course presents the fundamental principles of biochemistry proliferation (start/restriction point control). The seminar relies heavily and biophysics, with an emphasis on methodologies. It addresses on studies in model organisms, but the emphasis throughout will be issues of protein and nucleic acid structure and the forces that on aspects of cell cycle control conserved among eukaryotes. underlie stability and govern the formation of specific three- Class length and frequency: 2.5-hour lecture and discussion, dimensional structures. -
Human Enhancement Technologies and Our Merger with Machines
Human Enhancement and Technologies Our Merger with Machines Human • Woodrow Barfield and Blodgett-Ford Sayoko Enhancement Technologies and Our Merger with Machines Edited by Woodrow Barfield and Sayoko Blodgett-Ford Printed Edition of the Special Issue Published in Philosophies www.mdpi.com/journal/philosophies Human Enhancement Technologies and Our Merger with Machines Human Enhancement Technologies and Our Merger with Machines Editors Woodrow Barfield Sayoko Blodgett-Ford MDPI • Basel • Beijing • Wuhan • Barcelona • Belgrade • Manchester • Tokyo • Cluj • Tianjin Editors Woodrow Barfield Sayoko Blodgett-Ford Visiting Professor, University of Turin Boston College Law School Affiliate, Whitaker Institute, NUI, Galway USA Editorial Office MDPI St. Alban-Anlage 66 4052 Basel, Switzerland This is a reprint of articles from the Special Issue published online in the open access journal Philosophies (ISSN 2409-9287) (available at: https://www.mdpi.com/journal/philosophies/special issues/human enhancement technologies). For citation purposes, cite each article independently as indicated on the article page online and as indicated below: LastName, A.A.; LastName, B.B.; LastName, C.C. Article Title. Journal Name Year, Volume Number, Page Range. ISBN 978-3-0365-0904-4 (Hbk) ISBN 978-3-0365-0905-1 (PDF) Cover image courtesy of N. M. Ford. © 2021 by the authors. Articles in this book are Open Access and distributed under the Creative Commons Attribution (CC BY) license, which allows users to download, copy and build upon published articles, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. The book as a whole is distributed by MDPI under the terms and conditions of the Creative Commons license CC BY-NC-ND. -
Hugh Herr Wants to Build a More Perfect Human
strategy+business ISSUE 85 WINTER 2016 Hugh Herr Wants to Build a More Perfect Human At MIT’s Media Lab, an engineer and biophysicist — and double amputee — is designing prosthetics that connect body and brain. BY SALLY HELGESEN REPRINT 16410 feature innovation 1 AT MIT’S MEDIA LAB, AN ENGINEER AND BIOPHYSICIST — AND HUGHDOUBLE AMPUTEE — IS DESIGNING PROSTHETICS THAT CONNECT BODY AND HERR BRAIN BY SALLY HELGESEN feature WANTS innovation TO BUILD A MORE 2 PERFECT HUMAN Sally Helgesen [email protected] is an author, speaker, and leadership development consultant whose most recent book is The Female Vision: Women’s Real Power at Work (with Julie Johnson; Berrett- Koehler, 2010). Hugh Herr sits at a table in his austere glass office we have to ask ourselves now is: What would be more in the famous Media Lab at the Massachusetts Institute useful here, skin or polymer? Fit, function, comfort, and feature of Technology, scrolling through images of a striking aesthetics will dictate our decisions.” fashion model born without a right forearm. As head of A computer scientist, mechanical engineer, and biomechatronics research at MIT and one of the world’s biophysicist, Herr is himself a double amputee. And innovation leading developers of wearable robotics, Herr is making his immersion in robotics was initially driven by a per- a point about how disability is becoming obsolete as the sonal quest to develop superior prosthetics. By analyz- boundary between humans and robots vanishes. ing human motion, studying how electronic devices The model, Rebekah Marine, strikes a pose on the interface with the nervous system, and using live mus- runway. -
Hhmi Bulletin 3 4 Hhmi Club
HHMI BULLETIN 4000 Jones Bridge Road • Chevy Chase, Maryland 20815-6789 Howard Hughes Medical Institute www.hhmi.org One Lump or Two? in this issue Once again, those fast-growing yeast find a way to turn a The Silicon Marvel long-held theory on its head. This time, it’s about prions, • Prions for Good which aren’t as universally nasty as once suspected. Some may actually help organisms evolve. The yeast colony shown here www.hhmi.org A Kaleidoscopic View contains a protein in its prion form. Because the prion, known as PSI+, is self-replicating and forms fibrous amyloids, the yeast look lumpy and bumpy—strikingly different from normally smooth yeast. Susan Lindquist’s group has found 19 yeast proteins that can switch back and forth between a normal and a prion version. The prions are thought to help the yeast adapt to changing conditions (see “A Silver Lining,” page 22). LIGHT MOVES v ol. 23 Heather True / Lindquist lab /no. 02 O b s e r v a t i O n s 16 Secret Agent MAn Skin cells do more than just cover our bodies. As a neurology resident, Stanley Prusiner saw Creutzfeldt–Jakob agent began to emerge. These data established, for the first time, that Keratinocytes, for example, anchor immune cells disease kill a patient in a matter of months. Researchers knew the rare a particular macromolecule was required for infectivity and that this within the epidermis, move and proliferate during neurodegenerative disease and scrapie, a similar disease in sheep, macromolecule was a protein …. wound healing, and even secrete inhibitory molecules were infectious but not as a result of a typical virus. -
ÉDITION Unexpected Sourcesusievents.Com of Inspiration François HISQUIN Président & Curateur D'usi
ÉDITION Unexpected Sourcesusievents.com of Inspiration François HISQUIN Président & Curateur d'USI VERS UNE SOCIÉTÉ INCLUSIVE, RÉSILIENTE ET ÉCORESPONSABLE Il y a 12 ans, en lançant la première conférence USI, nous avions la conviction que l’IT jouerait un rôle fondamental dans la transformation de nos Sociétés. Nos convictions n’ont pas changé. Résolument visionnaires, nous souhaitons offrir à tous une conférence novatrice et singulière, pour explorer, challenger et questionner les grands enjeux de notre avenir. Au service, dans un premier temps, d’un développement purement économique, les technologies sont aujourd’hui présentes dans toutes les strates de la société et nous poussent à redéfinir nos pratiques, nos valeurs et notre responsabilité. Face à l’immensité des enjeux, le seul objectif qui vaille, celui d’une société inclusive, résiliente, écoresponsable et offrant à tous une meilleure qualité de vie, ne pourra être atteint qu’en mobilisant toutes les ressources possibles. Les technologies sont souvent tenues comme grandes responsables de nos maux, mais ne renferment-elles pas une partie de la solution ? USI décrypte les transformations sociétales au sens large en conviant des visionnaires engagés. Philosophes, chercheurs, experts en cybersécurité, économistes, sociologues, scientifiques, éthologues, ou encore astrophysiciens... Tous ont choisi USI pour nous aider à donner du sens à nos transformations. Donner du sens, mais aussi du temps. Laisser la part belle à la créativité et à la réflexion, avant de passer à l’action. Car agir, -
The Age of Living Machines
THE AGE OF LIVING MACHINES HOW BIOLOGY WILL BUILD THE NEXT TECHNOLOGY REVOLUTION SUSAN HOCKFIELD W. W. NORTON & COMPANY Independent Publishers Since 1923 New York | London TO TOM AND ELIZABETH, FOR THEIR CONSTANT PATIENCE, WISDOM, AND LOVE. CONTENTS Prologue 1 WHERE THE FUTURE COMES FROM 2 CAN BIOLOGY BUILD A BETTER BATTERY? 3 WATER, WATER EVERYWHERE 4 CANCER-FIGHTING NANOPARTICLES 5 AMPLIFYING THE BRAIN 6 FEEDING THE WORLD 7 CHEATING MALTHUS, ONCE AGAIN: Making Convergence Happen Faster Acknowledgments Notes Index PROLOGUE For the last couple of decades, as a dean and then provost at Yale, and then as president and now president emerita of the Massachusetts Institute of Technology (MIT), I’ve had the privilege of looking over the scientific horizon, and what I’ve seen is breathtaking. Ingenious and powerful biologically based tools are coming our way: viruses that can self-assemble into batteries, proteins that can clean water, nanoparticles that can detect and knock out cancer, prosthetic limbs that can read minds, computer systems that can increase crop yield. These new technologies may sound like science fiction, but they are not. Many of them are already well along in their development, and each of them has emerged from the same source: a revolutionary convergence of biology and engineering. This book tells the story of that convergence—of remarkable scientific discoveries that bring two largely divergent paths together and of the pathbreaking researchers who are using this convergence to invent tools and technologies that will transform how we will live in the coming century. We need new tools and technologies. -
Phi Beta Kappa Visiting Scholars 1956-57- 2016-2017 (61 Years)
Phi Beta Kappa Visiting Scholars 1956-57- 2016-2017 (61 years) 2016-2017 (112 visits) Adorno, Rolena Spanish/Latin American literatur Yale Bialek, William physics Princeton Ehrman, Bart D. religion, New Testament UNC-Chapel Hill Grosz, Barbara J. computer science Harvard Hochschild, Jennifer L. political science Harvard Kitcher, Philip philosophy Columbia Lester, Marsha I. chemistry Penn Morse, Nora Naranjo fine arts, poetry, sculpture Espanola, NM Rodgers, Daniel T. American history & culture Princeton Sabloff, Jeremy A. anthropology, Maya Penn Weiman, David F. economic history Barnard Wexler, Laura American studies Yale Witt, John Fabian law, American history Yale Wright, Patricia anthropology/primatology SUNY, Stony Brook Xiao, Shuhai geobiology/paleobiology Virginia Tech 2015-2016 (100 visits) Michael Bérubé English, disability studies Penn State Caroline Bruzelius art, art history Duke David K. Campbell physics, engineering Boston U. Hazel V. Carby African American studies Yale Carol Greenhouse anthropology, sociocultural Princeton David B. Grusky sociology, inequality, poverty Stanford Rigoberto Hernandez biochemistry, diversity studies Georgia Tech Mae Ngai history, Asian American studies Columbia Judith Resnik law Yale Timothy Rowe paleontology, geology UTAustin Larry A. Silver art history, Renaissance Penn Harold W. Stanley political science, elections Southern Methodist Richard Sylla American economic history NYU Blaire Van Valkenburgh vertebrate paleonbiology UCLA Vincent L. Wimbush religion Inst.SignifyingScriptures 2014-2015 (96 visits) Jeffrey C. Alexander sociology Yale William Y. Arms computer science Cornell Wendy Brown political science UCBerkeley Caroline Bruzelius art, art history Duke Philip J. Deloria history, American Indian Michigan Gerald Graff English, education Illinois at Chicago Kathleen McGarry economics, aging UCLA Gregory A. Petsko neurology, neuroscience Cornell Med. -
Engineering Photocrosslinkable Bicomponent Hydrogel Constructs
www.advancedsciencenews.com www.advhealthmat.de FULL PAPER Engineering Photocrosslinkable Bicomponent Hydrogel Constructs for Creating 3D Vascularized Bone Mehdi Kazemzadeh-Narbat, Jeroen Rouwkema, Nasim Annabi,* Hao Cheng, Masoumeh Ghaderi, Byung-Hyun Cha, Mansi Aparnathi, Akbar Khalilpour, Batzaya Byambaa, Esmaiel Jabbari, Ali Tamayol,* and Ali Khademhosseini* 1. Introduction Engineering bone tissue requires the generation of a highly organized vasculature. Cellular behavior is affected by the respective niche. Directing Even though bone tissue has a remarkable cellular behavior and differentiation for creating mineralized regions sur- regenerative capacity, large bone defects are often unable to fully heal on their rounded by vasculature can be achieved by controlling the pattern of own partially due to the destruction of osteogenic and angiogenic niches. This manuscript reports on engineering the local vascular network.[1,2] Traditional vascularized bone tissues by incorporating osteogenic and angiogenic approaches for treatment of large bone cell-laden niches in a photocrosslinkable hydrogel construct. Two-step defects include autologous bone transplan- photolithography process is used to control the stiffness of the hydrogel and tation and cancellous bone allografts.[3] distribution of cells in the patterned hydrogel. In addittion, osteoinductive Allografts carry the risk of immune rejec- tion.[4–7] Autologous bone grafts, particu- nanoparticles are utilized to induce osteogenesis. The size of microfabricated larly vascularized grafts of the fibula and constructs has a pronounced effect on cellular organization and function. iliac crest, are effective in the treatment It is shown that the simultaneous presence of both osteogenic and of large bone defects since they provide angiogenic niches in one construct results in formation of mineralized both an osteogenic environment and a [8] regions surrounded by organized vasculature. -
Elaine Fuchs
Elaine Fuchs Date of Birth 5 May 1950 Place Illinois, USA Nomination 27 March 2018 Field Stem cell and cancer biology Title Investigator of the Howard Hughes Medical Institute and Rebecca C. Lancefield Professor of the Rockefeller University Professional address Howard Hughes Medical Institute The Rockefeller University 1230 York Avenue, Box 300 New York, NY 10065 USA Most important awards, prizes and academies Academic qualifications: University of Illinois, B.S. Chemistry, 1972, Highest distinction in the curriculum; Princeton University, Ph.D., Biochemistry, 1977; Massachusetts Inst. Technology, Postdoctoral Fellow, 1977-80. Academies: American Academy of Arts and Sciences (‘94); National Academy of Medicine (‘94); National Academy of Sciences (‘96); American Philosophical Society (‘05); EMBO Foreign Member (’10); Academy of the American Association for Cancer Research ('13); Academy of the American Society for Cell Biology (’16). Major Elected Posts in National/International Societies: President, American Society for Cell Biology, '01; National Academy of Sciences, Council '01-'04; President, Harvey Society, '07; President, International Society for Stem Cell Research (ISSCR), '10; New York Academy of Sciences Board of Governors ('11-); National Academy of Medicine, Council ('14-). Honours: University of Illinois 1968-1972: Phi Beta Kappa; Agnes Sloan Larson Award; Iota Sigma Pi Award; Reynold Clayton Fuson Award; James Scholar; Bronze Tablet (top 3% Graduating Class). Massachusetts Institute of Technology 1977-1979: Damon Runyon Postdoctoral Fellow. University of Chicago 1980-2002: Searle Scholar ('81-'83); Presidential Young Investigator Award ('84-'89); Montagna Award (Society for Investigative Dermatology, '95); Senior Women's Career Achievement Award (American Society for Cell Biology '97); Richard Lounsbery Award (National Academy of Sciences, '01).