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Improving Outcomes for Noncommunicable Diseases In
FOR NONCOMMUNICABLE DISEASES IN LOW AND MIDDLEINCOME COUNTRIES KENNETH A. LABRESH, MD, EDITOR RTI Press ©2016 RTI International. All rights reserved. The RTI Press mission is to disseminate Credit must be provided to the author and information about RTI research, analytic tools, source of the publication when the content and technical expertise to a national and is quoted. No part of this publication may international audience. RTI Press publications be reproduced in any form by any electronic are peer-reviewed by at least two independent or mechanical means without permission in substantive experts and one or more Press writing from the publisher. RTI International editors. is a registered trademark and a trade name of RTI International is an independent, nonprofit Research Triangle Institute. research organization dedicated to improving the human condition by turning knowledge into practice. RTI offers innovative research and technical services to governments and businesses worldwide in the areas of health and pharmaceuticals, education and training, surveys and statistics, advanced technology, international development, economic and social policy, energy and the environment, and laboratory testing and chemistry services. Library of Congress Control Number: 2016949680 ISBN 978-1-934831-17-5 (refers to print version) RTI Press publication No. BK-0017-1608 http://dx.doi.org/10.3768/rtipress.2016.bk.007.1608 www.rti.org/rtipress Cover design: Dayle Johnson This publication is part of the RTI Press Book series. RTI International 3040 East Cornwallis Road, PO Box 12194 Research Triangle Park, NC 27709-2194, USA [email protected] www.rti.org Contents Foreword v Preface ix Introduction xi 1. -
An^ Fluxes Were Rifest
Special Articles AN ACCOUNT OF INDIAN MEDICINE other places on the west coast. After return- ing to England in 1682 he published a BY ' learned and delightful book on India, A new JOHN FRYER, m.d., f.r.s. account of East India and Persia,' which is (1650-1733 A.D.) the basis for this article. By D. V. S. EEDDY Vizagapatam Medical topography : of John Fryer, m.d. (Cantab.), f.r.s., may be Bombay Writing Bombay, Fryer says rightly described as the most observant and that the president has his chaplains, physicians, and domestics. He also learned of all the physicians and surgeons of chyrurgeons refers to the East India Company in the 17th century. the sickly progeny of English women. in He came out to India 1673 and served at 'This may be attributed to their living at large not various settlements in this country and Persia debarring themselves wine and strong drink which, till 1682. During his journey to his immoderately used, influence the blood and spoils the station, milk in these hot as Aristotle he visited Fort St. and Masuli- countries, long ago Surat, George declared. The natives abhor all heady liquours for on patam the Coromandel coast, and Goa and which reason they approve better nurses.' -I Jan., 1940] JOHN FRYER'S ACCOUNT OF INDIAN MEDICINE : REDDY 35 a of the Dust and the of the Air: 'The have only Eyes by fiery Temper Fryer also adds English In the Rains, Fluxes, Apoplexies, and all. Distempers church or burying place but neither ^ ^hospital of the Brain, as well as Stomach.' both which are mightily to be desired.' some diseases Fryer notes the unhealthiness of Bombay. -
2020 Annual Report Our Mission
2020 ANNUAL REPORT OUR MISSION Cure Alzheimer’s Fund is a nonprofit organization dedicated to funding research with the highest probability of preventing, slowing or reversing Alzheimer’s disease. Annual Report 2020 MESSAGE FROM THE CHAIRMEN 2 THE MAIN ELEMENTS OF THE PATHOLOGY OF ALZHEIMER’S DISEASE 9 RESEARCH AREAS OF FOCUS 10 PUBLISHED PAPERS 12 CURE ALZHEIMER’S FUND CONSORTIA 20 OUR RESEARCHERS 22 2020 FUNDED RESEARCH 32 2020 EVENTS TO FACILITATE RESEARCH COLLABORATION 68 MESSAGE FROM THE PRESIDENT 70 2020 FUNDRAISING 72 2020 FINANCIALS 73 OUR PEOPLE 74 OUR HEROES 75 AWARENESS 78 IN MEMORY AND IN HONOR 80 SUPPORT OUR RESEARCH 81 Message From The Chairmen Dear Friends, 2020 was a truly remarkable year: • Despite the COVID-19 pandemic, we were fully functional with all of our wonderful staff working from their homes. We were able to pay and retain all of our employees, thanks to the generosity of our directors. • And, amazingly, we were able to increase our fundraising by 2%, in this very tough year, to $25.9 million provided by 21,000 donors. • The above enabled us to fund 59 research grants totaling $16.5 million. We have, since inception, financed 525 grants, representing $125 million in cumulative funding through March 2021. • We have one therapy well on its way through clinical trials, and another expected to enter clinical trials in late 2021 or 2022. Our Scientists Approximately 175 scientists affiliated with 75 institutions around the world are working on our projects. They are profiled in the pages that follow. Many labs faced funding challenges during COVID-19, and our consistent support was very beneficial for ensuring that vital staff could be retained and scientific progress was preserved. -
Models of Federal Research & Development
1 Growing from a handful of scientists in central North Carolina in 1959 to a staff of more than 3,700 in more than 75 countries today, RTI is one of the world’s leading independent, nonprofit research and development organizations. Our activities both mirror and support national priorities and policies, as well as diverse commercial, industrial, and academic endeavors. For instance, as public and government interest in environmental protection grew in the 1960s, so did related programs at RTI, building on our expertise in statistical, physical, and life sciences. 2 Today, all of RTI’s research activities are guided by our mission to improve the human condition. Researchers hold advanced degrees in more than 125 disciplines; their collaborative expertise is recruited to better understand, analyze, measure, and solve many of the most complex challenges to the planet and humankind. Health research, RTI’s largest field of study, spans a range of specialties from the human genome to local health education. Researchers across the institute are studying substance abuse among teenagers, the relationship between children’s television viewing habits and obesity, and the health implications of the dietary supplement ephedra. Others are evaluating the prevalence of sexual assault among prison inmates and the relationship between hypothermia and infants with encephalopathy. While one multidisciplinary team of researchers recently forged a unique private‐public partnership to bring an affordable new tuberculosis drug—PA‐824—to clinical trials, another group developed a data‐mining and predictive analytics software program to help police forces optimize their resources to improve public safety. RTI’s medicinal chemistry researchers discovered two successful cancer drugs, Camptothecin and Taxol. -
Mayo Clinic Alumni Magazine, 2020, Issue 1
MAYOALUMNI CLINIC ISSUE 1 2020 WHOLE-PERSON CARDIO-ONCOLOGY STETHOSCOPE CARE EMERGES GIFTS LETTER FROM THE SECRETARY-TREASURER I’m delighted to address you for the first time as secretary-treasurer of the Alumni Association. In succeeding Peter Amadio, M.D. (OR ’83), I have big shoes to fill and benefited from his mentorship in the past few months. I look forward to being formally involved in the Alumni Association. I have been fortunate to spend my entire career at Mayo Clinic, where I gained my professional footing and chose to dedicate myself to patient care, education and research. This issue of Mayo Clinic Alumni illustrates diagnostic expertise for patients with medical mysteries. As a specialist who sees patients M. MOLLY MCMAHON, M.D. (ENDO ’87) receiving parenteral or enteral nutrition, I’m • Secretary-Treasurer, Mayo Clinic Alumni Association often impressed by how we collaborate to find • Division of Endocrinology, Diabetes, Metabolism, the answers that have eluded patients for so long. and Nutrition And, importantly, Mayo Clinic does this in such a • Mayo Clinic in Rochester timely, efficient way that patients and their referring physicians often are astounded. Putting the needs of patients first involves not only accurate diagnosis but also respect for their time and resources. Please I encourage you to register for the September take the time to read the profiles of the four out- Alumni Association International Meeting in Lisbon, standing practice areas featured in this issue. Portugal. It’s an opportunity to renew your Mayo Also included in this issue is a Women’s History Clinic connections and learn and relax in a beautiful Month story featuring six of Mayo Clinic’s early setting. -
Volume Xlv(3) • August 2019 2
AGLP In this issue . The Association of LGBTQ Psychiatrists VOLUME XLV(3) • AUGUST 2 0 1 9 IPS NewYork 2019 1 Editor’s Column 2 Erick Meléndez, M.D. President’s Column Howard Rubin, M.D. 3 President-Elect’s Column Amir Ahuja, M.D. 4 Vice-President’s Column 4 Pratik Bahekar, M.D. JGLMH Update 4 Chris McIntosh, M.D., Co-Editor Queer Cultural Events of Interest 6 Gene Nakajima, M.D., and Howard Rubin, M.D. New York City AGLP Sponsors 7 AGLP Organizing for the APA-IPS Meeting in New York Subspeciality Meetings 8 Eric Yarbrough, M.D. October 3-6, 2019 lease join AGLP: The Association of LGBTQ Psychiatrists (www.aglp.org) at this year's IPS, Denial of Care Rule Delayed 8 Roy Harker, C.A.E., Executive Director the APA’s Fall meeting in New York City. We will be organizing a plethora of LGBTQ events! Forward this newletter to colleagues who might be interested in attending, to listserves, or Fryer Award Contributors 9 P other social media outlets. Registration: Register now to get the lowest rate. Welcome to our New Members 9 https://www.psychiatry.org/psychiatrists/meetings/ips-the-mental-health-services-conference/regis- tration/registration-rates AGLP Annual Meeting Minutes Sarah Noble, D.O., Secretary 10 Preliminary schedule: LGBTQ Sessions Thursday, October 3 Membership Application Forms 14 10:00am - 11:30am In the Shadow of History: The LGBTQ (Lesbian, Gay, Bisexual, Transgender, Queer) Psychiatric Experience. HOWARD RUBIN, MD, ADRIANA DE JULIO, MD, HARSHIT SHARMA, AMILCAR TIRADO, MD, SAUL LEVIN, MD Friday, October 4 1:00pm - 2:30pm The -
David H. Schanzer
DAVID H. SCHANZER 166 Rubenstein Hall 505 Lakeshore Lane Box 90316 Chapel Hill, NC 27514 Durham, NC 27708 (919) 933 5330 (919) 613-9279 [email protected] EDUCATION Harvard Law School, J.D., cum laude (1989) Editor, Harvard Law Review (1987-89) Harvard College, A.B., cum laude in Government (1985) PROFESSIONAL EXPERIENCE Associate Professor of the Practice, Sanford School of Public Policy, Duke University (July, 2005 – present) Appointed to rank of Associate Professor, September 2009. Visiting Professor of the Practice, 2005-09. Courses: 9/11 & Its Aftermath (Fall 2005, Fall 2006, Fall 2008) Counterterrorism Law & Public Policy (Fall 2007, Fall 2009) Guest lecturers: Duke Law School, National Security Law (every semester); Duke University, Global Health; Sanford School of Public Policy – SAFEA Program for Chinese Government Officials; Duke University – Natural Disasters Course (2008, 2010). Co-Director, Institute for Homeland Security Solutions (September, 2008 – present) • Co-directing and managing complex, inter-institutional research organization funded through grant funds from the U.S. Department of Homeland Security. Primarily responsible for strategy and outreach. Work with prime contractor, RTI International; manage and oversee subcontracts between RTI and both Duke University and University of North Carolina Chapel Hill. • Research activities focus on how human behavior impacts the homeland security mission. • Institute has been awarded about $11.5 million in funding since 2008. • Institute received RTI President’s Award – 2009 • Led subject matter panel evaluating privacy aspects of a large scale DHS intelligence analysis program – The Violent Intent Modeling & Simulation project. Director, Triangle Center on Terrorism and Homeland Security (July, 2005 - present) • Founded the Triangle Center on Terrorism and Homeland Security, a multi-disciplinary research initiative on counterterrorism and domestic security issues jointly sponsored by Duke University, University of North Carolina Chapel Hill, and Research Triangle Institute, International. -
European Doctors in Pre-Colonial India
Perspectives The truth behind the legend: European doctors in pre-colonial India RAJESH KOCHHAR Indian Institute of Astrophysics, Koramangala, Bangalore 560 034, India (Fax, 91-80-5534043; Email, rkk@ iiap.ernet.in) The aim of this article is to point out that the medical history of India in the seventeenth century needs to be studied for its bearing on the history of medical science in this country. During the period 1644-1717, European physicians in India were sought and pampered by the Indian ruling class. English doctors were able to translate this professional goodwill into concrete commercial concessions for the British East India Company. The concessions gave the Company an edge over its rivals, and, more importantly, gave it a cause to fight for. In consequence, the Company was transformed from a vaishya (trading) organization into a kshatriya (territorial) one. These conclusions warrant a more rigorous professional study of European doctors vis-a-vis their Indian counterparts in the pre-colonial period. 1. Introduction 2. Knowledge of Indian medicine in Europe: the story of Garcia d'Orta We live in an age of cultural Copernicanism (Kochhar 1999). In cosmology the Copernican principle states that The Europeans brought not only syphilis from their ocean the universe has no preferred location or direction. In a voyages but also new remedies. There was a concerted similar fashion, cultural Copernicanism asserts that no attempt to incorporate the traditional knowledge of the cultural, geographical or ethnic area can be deemed to be Americas and the East Indies into the European a benchmark to be used to evaluate and judge others. -
The Role of Neurotensin Receptors on Visceral Pain and Activity Levels in Mice
UNF Digital Commons UNF Graduate Theses and Dissertations Student Scholarship 2015 The Role of Neurotensin Receptors on Visceral Pain and Activity Levels in Mice. Christopher J. Walker University of North Florida Suggested Citation Walker, Christopher J., "The Role of Neurotensin Receptors on Visceral Pain and Activity Levels in Mice." (2015). UNF Graduate Theses and Dissertations. 588. https://digitalcommons.unf.edu/etd/588 This Master's Thesis is brought to you for free and open access by the Student Scholarship at UNF Digital Commons. It has been accepted for inclusion in UNF Graduate Theses and Dissertations by an authorized administrator of UNF Digital Commons. For more information, please contact Digital Projects. © 2015 All Rights Reserved The Role of Neurotensin Receptors on Visceral Pain and Activity Levels in Mice. By Christopher James Walker A Thesis Submitted to the Department of Psychology in partial fulfillment of the requirements for the degree of Master of Arts in General Psychology UNIVERSITY OF NORTH FLORIDA July, 2015 Unpublished work © Christopher James Walker This Thesis titled The Role of Neurotensin Receptors on Visceral Pain and Activity Levels in Mice is approved: Dr. Lori Lange Committee Chair ______________________________ __________________ Dr. John Fryer Committee Member Accepted for the Psychology Department: Dr. Micheal Toglia Department Chair Accepted for the College of Arts and Sciences: Dr. Barbara A. Hetrick Dean of the College of Arts and Sciences Accepted for the University: Dr. John Kantner Dean of the Graduate School iii DEDICATION To my loving wife Stephanie. Without her I would have never been able to accomplish so much. She is my love and my life. -
RTI International
RTI International About Us • RTI International is an independent, nonprofit research • RTI scientists have published seminal studies and institute dedicated to improving the human condition. are experts in the top issues of the day, including the • Established in 1958, RTI provides government and opioid epidemic, marijuana, e-cigarettes, campus sexual private-sector clients with independent, objective, assault, Zika virus, data for development, drones, and and scientifically rigorous research, development, and policing research. technical services in more than 50 countries. • RTI experts hold degrees in scientific, technical, • RTI researchers have expertise across a range of subject and professional disciplines across the social and areas, including health, education and workforce laboratory sciences, engineering, and international development, international development, energy development fields. research, environmental sciences, social and justice • RTI has close ties with some of the world’s leading policy, and food security and agriculture. research universities—including Columbia, Harvard, Johns Hopkins, and the University of Michigan—and top Institute Fast Facts universities in North Carolina, including North Carolina State University, Duke University, North Carolina • Established in 1958 Central University, and the University of North Carolina • Mission: To improve the human condition by turning at Chapel Hill. knowledge into practice • Headquartered on a 180-acre campus in Research More Information Triangle Park, North Carolina 919.541.6000 • Twelve U.S. regional offices, twelve international offices, [email protected] and three subsidiaries www.rti.org • Nearly 5,000 employees worldwide RTI International 3040 E. Cornwallis Road, PO Box 12194 • Ongoing projects in more than 50 countries Research Triangle Park, NC 27709-2194 USA • Fiscal year 2018 revenue: $960 million RTI 11434 R1 1219 RTI International is an independent, nonprofit research institute dedicated to improving the human condition. -
NHDES Department of Environmental Services Robert R
„ , ,N0W5'20Phl2!5GRCUD The State of New Hampshire NHDES Department of Environmental Services Robert R. Scott, Commissioner November 2, 2020 His Excellency, Governor Christopher T. Sununu and the Honorable Council State House Concord, New Hampshire 03301 REQUESTED ACTION Authorize the Department of Environmental Services (NHDES) to enter into a SOLE SOURCE agreement with Research Triangle Institute (RTI),(VC# 171105-B001), Research Triangle Park, NC In the amount of $198,908 for the modernization of the RIverTrak* Forecast System used to track water flows, effective upon Governor and Council approval through December 31, 2022. 100% Capital (General) Funds. Funding Is available m the account as follows: FY 2021 03-44-442030-12670000-034-500161 $198,908 Dept. Environmental Services, 19-146:1-VI:A Dam Repair & Reconstruction, Capital Projects EXPLANATION Under RSA 483-D:l, NHDES was directed to develop a computer model to assist In managing flows In the WInnlpesaukee River Basin. To fulfill this requirement, In 2001, NHDES procured the services of Riverside Technology Incorporated (now doing business as Research Triangle Institute), a qualified engineering consultant, in accordance with the procedures specified In RSA 21-1:22, to provide and support the RIverTrak* Forecast System. This agreement to modernize the RIverTrak* Forecast System Is SOLE SOURCE because the forecasting and reservoir operations modeling systems produced by RTI are custom applications of software modules that can only upgraded by RTI. A complete ground-up redevelopment of the underlying hydrologic models and Information, developed in the original contract with RTI, by another vendor would not be cost effective and would unnecessarily risk Interruption and/or degradation of modeling and publicly available data functions of the existing models. -
Convocation of Distinguished Fellows
th 64 Convocation of Distinguished Fellows 2020 Annual Meeting Advancing Quality: Challenges & Opportunities TING April 27, 2020 CELEBRA 64th Convocation of Distinguished Fellows 1 64th Convocation of Distinguished Fellows 2 64th Convocation of Distinguished Fellows Contents Page # Honorees ............................................................................................................ 4-18 50-Year Distinguished Life Fellows, Life Fellows and Life Members 1970-2020 .................................................................... 4-7 2020 Distinguished Life Fellows .......................................................... 8-9 2020 Life Fellows ....................................................................................... 10-11 2020 Distinguished Fellows ................................................................... 12-13 2020 Fellows ................................................................................................ 14-16 2020 International Distinguished Fellows ........................................ 17 2020 International Fellows ..................................................................... 18 Special Presidential Commendation ................................................... 19-20 Distinguished Service Award ................................................................. 21-22 Organizational Distinguished Service Award .................................. 22 Award Lectures .............................................................................................. 23-34 Administrative