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Ongoing Research Project Overview Ongoing Research Project Overview Ongoing Research Project Overview Ongoing Research Project Overview Department for Maternal, Newborn, Child & Adolescent Health An innovative approach to jump start simplified management of sick young infants with PSBI where referral is not possible for potential scale-up Background WHO developed a guideline ‘managing possible serious bacterial infection (PSBI) in young /Rationale infants when referral is not feasible’ in 2015. This guideline will make treatment more accessible and acceptable to families, as well as easier and less costly for the system to implement, when referral is not feasible. Study We used an innovative approach using implementation research to spearhead facilitated Questions & policy adoption and readiness for scale up for simplified management of sick young infants Design with possible serious bacterial infection (PSBI) where referral is not feasible through the following: - Policy dialogue and orientation meetings held at national and subnational level. - Demonstration sites established in 11 sites in six countries to demonstrate feasibility of delivering simplified antibiotic regimens to young infants with PSBI where referral is not feasible. Programme objective: To have at least 80% coverage of appropriate treatment of all young infants up to 59 days of age with possible serious bacterial infection (PSBI) Research question: What needed to be done to reach the achieved coverage? Programmatic The purpose of this work is to implement the WHO guidelines in a programme setting to Implications inform and accelerate the use of simplified management of sick young infants up to two months of age with PSBI in selected countries in Africa and Asia for eventual scale up at country level. Data collection phase has been completed at all study sites. Findings of this implementation research will be used to up scale the WHO PSBI guidelines at national and subnational level. Locations & Democratic Collaborators Republic of Kinshasa School of Public Health (Prof. Antoinette Tshefu) Congo Jimma University (Prof Tsinuel Girma, Dr Workineh Tesfaye) Ethiopia Mekelle University (Prof Leul Abadi and Dr Loko Abrham) The INCLEN Trust International, New Delhi (Haryana site: Prof Narendra Arora) Centre for Health Research and Development, Society for Applied Studies (CHRD-SAS) New Delhi (Himachal Pradesh site: Dr Temsunaro Rongsen India Chandola) K.E.M. Hospital Research Centre, Pune (Maharashtra site: Dr Ashish Bavdekar) Department of Paediatrics, King George’s Medical University, Lucknow (Uttar Pradesh site: Dr Shally Awasthi) Save the Children International, Malawi (Mr Gomeszgani Jenda). College of Malawi Medicince, Blantyre (Dr Don P. Mathanga), Save the Children International, USA (Eric Starbuck). College of Medicine, University College Hospital, Ibadan (Ibadan: Dr. Nigeria Adejumoke Idowu Ayede and Professor Adegoke Gbadegesin Falade) For further information, please contact: Yasir Bin NISAR [email protected] Ahmadu Bello University, Zaria (Prof Robinson Wammanda and Prof William Ogala) Aga Khan University, Karachi (Dr Sajid Soofi and Dr Shabina Ariff) Pakistan PPHI, Sindh Pakistan (Dr Riaz Memon). Data Collection October 2014 – April 2019 Funders Bill & Melinda Gates Foundation (BMGF), Alliance for Health Policy and Systems Research (AHPSR), Save the Children (SC), Canada Web https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=373300&isReview=true For further information, please contact: Shamim QAZI Yasir Bin NISAR [email protected] [email protected] .
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